metoprolol has been researched along with Postural Orthostatic Tachycardia Syndrome in 11 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Postural Orthostatic Tachycardia Syndrome: A syndrome of ORTHOSTATIC INTOLERANCE combined with excessive upright TACHYCARDIA, and usually without associated ORTHOSTATIC HYPOTENSION. All variants have in common an excessively reduced venous return to the heart (central HYPOVOLEMIA) while upright.
| Excerpt | Relevance | Reference |
|---|---|---|
| " β-adrenergic blockade metoprolol in the treatment of children with postural orthostatic tachycardia syndrome (POTS)." | 9.15 | Midodrine hydrochloride is effective in the treatment of children with postural orthostatic tachycardia syndrome. ( Chen, L; Du, J; Jin, H; Qin, J; Sun, J; Tang, C; Wang, L, 2011) |
| " β-adrenergic blockade metoprolol in the treatment of children with postural orthostatic tachycardia syndrome (POTS)." | 5.15 | Midodrine hydrochloride is effective in the treatment of children with postural orthostatic tachycardia syndrome. ( Chen, L; Du, J; Jin, H; Qin, J; Sun, J; Tang, C; Wang, L, 2011) |
| "There are differences in postural tachycardia syndrome (POTS) incidence and manifestations in children between the sexes." | 1.91 | The influence of sex on the treatment of postural tachycardia syndrome in children. ( Cai, H; Peng, Y; Wang, C; Wang, S; Wang, Y; Zhang, J; Zou, R, 2023) |
| "In the OI spectrum, postural tachycardia syndrome (POTS) accounted for 826 cases (39." | 1.72 | [A 10-year retrospective analysis of spectrums and treatment options of orthostatic intolerance and sitting intolerance in children]. ( Chen, YH; Cui, YX; DU, JB; Jin, HF; Liao, Y; Liu, P; Liu, XQ; Qi, JG; Sun, CF; Sun, Y; Wang, YL; Xu, WR; Yan, H; Zhang, CY; Zhang, QY, 2022) |
| "Metoprolol was used to treat children with POTS." | 1.42 | Plasma C-type natriuretic peptide as a predictor for therapeutic response to metoprolol in children with postural tachycardia syndrome. ( Chen, SY; Du, J; Han, Z; Jin, H; Li, H; Li, X; Lin, J; Liu, P; Tang, C; Wang, Y, 2015) |
| "Metoprolol is clinically used to treat postural tachycardia syndrome (POTS) in children, but its effectiveness is unsatisfactory." | 1.40 | Usefulness of plasma copeptin as a biomarker to predict the therapeutic effectiveness of metoprolol for postural tachycardia syndrome in children. ( Du, J; Du, S; Jin, H; Lin, J; Tang, C; Yang, J; Zhao, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 5 (45.45) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, YX | 1 |
| DU, JB | 4 |
| Zhang, QY | 2 |
| Liao, Y | 3 |
| Liu, P | 3 |
| Wang, YL | 2 |
| Qi, JG | 1 |
| Yan, H | 1 |
| Xu, WR | 1 |
| Liu, XQ | 2 |
| Sun, Y | 1 |
| Sun, CF | 1 |
| Zhang, CY | 2 |
| Chen, YH | 1 |
| Jin, HF | 4 |
| Xu, BW | 1 |
| Li, XY | 2 |
| Tang, CS | 2 |
| Peng, Y | 1 |
| Wang, S | 2 |
| Zou, R | 2 |
| Cai, H | 2 |
| Zhang, J | 1 |
| Wang, Y | 3 |
| Wang, C | 2 |
| Ding, Y | 1 |
| Tan, C | 1 |
| Yang, M | 1 |
| Li, F | 1 |
| Wang, YY | 1 |
| Han, ZH | 1 |
| Huang, YQ | 1 |
| Zhao, J | 1 |
| Du, S | 1 |
| Yang, J | 1 |
| Lin, J | 2 |
| Tang, C | 3 |
| Du, J | 4 |
| Jin, H | 3 |
| Zhang, Q | 1 |
| Chen, X | 1 |
| Li, J | 1 |
| Han, Z | 1 |
| Li, H | 1 |
| Chen, SY | 1 |
| Li, X | 1 |
| Chen, L | 2 |
| Wang, L | 1 |
| Sun, J | 1 |
| Qin, J | 1 |
| Zhang, FW | 1 |
| Kimpinski, K | 1 |
| Figueroa, JJ | 1 |
| Singer, W | 1 |
| Sletten, DM | 1 |
| Iodice, V | 1 |
| Sandroni, P | 1 |
| Fischer, PR | 1 |
| Opfer-Gehrking, TL | 1 |
| Gehrking, JA | 1 |
| Low, PA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety and Efficacy of Midodrine Hydrochloride in the Management of Refractory Ascites Due to Cirrhosis in Children: a Pilot Study[NCT04043858] | 20 participants (Anticipated) | Interventional | 2020-06-05 | Recruiting | |||
| Comparison of Effect of Propranolol, Bisoprolol, Pyridosgitmine in Postural Orthostatic Tachycardia Syndrome (POTS) and Prognosis After Medical Treatment[NCT02171988] | Phase 4 | 150 participants (Actual) | Interventional | 2014-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for metoprolol and Postural Orthostatic Tachycardia Syndrome
| Article | Year |
|---|---|
Midodrine hydrochloride is effective in the treatment of children with postural orthostatic tachycardia syndrome.
Topics: Adolescent; Adrenergic alpha-1 Receptor Agonists; Child; Disease-Free Survival; Female; Follow-Up St | 2011 |
[Therapies for postural tachycardia syndrome in children].
Topics: Adolescent; Child; Female; Humans; Male; Metoprolol; Midodrine; Postural Orthostatic Tachycardia Syn | 2011 |
9 other studies available for metoprolol and Postural Orthostatic Tachycardia Syndrome
| Article | Year |
|---|---|
[A 10-year retrospective analysis of spectrums and treatment options of orthostatic intolerance and sitting intolerance in children].
Topics: Child; Electrolytes; Female; Humans; Male; Metoprolol; Midodrine; Orthostatic Intolerance; Postural | 2022 |
A predictive model of response to metoprolol in children and adolescents with postural tachycardia syndrome.
Topics: Adolescent; Child; Heart Rate; Humans; Metoprolol; Postural Orthostatic Tachycardia Syndrome; ROC Cu | 2023 |
The influence of sex on the treatment of postural tachycardia syndrome in children.
Topics: Child; Female; Heart Rate; Humans; Male; Metoprolol; Postural Orthostatic Tachycardia Syndrome; Retr | 2023 |
Heart Rate and Heart Rate Difference Predicted the Efficacy of Metoprolol on Postural Tachycardia Syndrome in Children and Adolescents.
Topics: Adrenergic beta-1 Receptor Antagonists; Case-Control Studies; Child; Female; Heart Rate; Humans; Mal | 2020 |
Baseline left ventricular ejection fraction associated with symptom improvements in both children and adolescents with postural tachycardia syndrome under metoprolol therapy.
Topics: Adolescent; Child; Humans; Metoprolol; Postural Orthostatic Tachycardia Syndrome; Retrospective Stud | 2021 |
Usefulness of plasma copeptin as a biomarker to predict the therapeutic effectiveness of metoprolol for postural tachycardia syndrome in children.
Topics: Adolescent; Anti-Arrhythmia Agents; Biomarkers; Child; Dose-Response Relationship, Drug; Electrocard | 2014 |
Orthostatic plasma norepinephrine level as a predictor for therapeutic response to metoprolol in children with postural tachycardia syndrome.
Topics: Adolescent; Child; Female; Heart Rate; Humans; Male; Metoprolol; Norepinephrine; Postural Orthostati | 2014 |
Plasma C-type natriuretic peptide as a predictor for therapeutic response to metoprolol in children with postural tachycardia syndrome.
Topics: Adolescent; Case-Control Studies; Child; Female; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; | 2015 |
A prospective, 1-year follow-up study of postural tachycardia syndrome.
Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adult; Anti-Inflammato | 2012 |