Compounds > metoprolol
Page last updated: 2024-10-31

metoprolol and Necrosis

metoprolol has been researched along with Necrosis in 9 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Patients with Killip class II or less anterior ST-segment-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention within 6 hours of symptoms onset were randomized to receive intravenous metoprolol (n=131) or not (control, n=139) before reperfusion."9.17Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri ( Acebal, C; Albarrán, A; Arias, M; Bastante, T; Cabrera, JA; Casado, I; Cuellas, C; de la Torre-Hernández, JM; Escalera, N; Fernández-Campos, MJ; Fernández-Friera, L; Fernández-Jiménez, R; Fernández-Ortiz, A; Fernández-Vázquez, F; Fuster, V; García-Álvarez, A; García-Prieto, J; García-Rubira, JC; García-Ruiz, JM; Goicolea, J; Hernández-Antolín, R; Ibanez, B; Iglesias-Vázquez, JA; Iñiguez, A; Jiménez-Borreguero, J; López-Romero, P; Macaya, C; Mateos, A; Pérez de Prado, A; Pizarro, G; Pocock, S; Rodriguez, MD; Ruiz-Mateos, B; Sánchez-Brunete, V; Sanz, G; Sanz-Rosa, D; Valenciano, J, 2013)
"Patients with Killip class II or less anterior ST-segment-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention within 6 hours of symptoms onset were randomized to receive intravenous metoprolol (n=131) or not (control, n=139) before reperfusion."5.17Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri ( Acebal, C; Albarrán, A; Arias, M; Bastante, T; Cabrera, JA; Casado, I; Cuellas, C; de la Torre-Hernández, JM; Escalera, N; Fernández-Campos, MJ; Fernández-Friera, L; Fernández-Jiménez, R; Fernández-Ortiz, A; Fernández-Vázquez, F; Fuster, V; García-Álvarez, A; García-Prieto, J; García-Rubira, JC; García-Ruiz, JM; Goicolea, J; Hernández-Antolín, R; Ibanez, B; Iglesias-Vázquez, JA; Iñiguez, A; Jiménez-Borreguero, J; López-Romero, P; Macaya, C; Mateos, A; Pérez de Prado, A; Pizarro, G; Pocock, S; Rodriguez, MD; Ruiz-Mateos, B; Sánchez-Brunete, V; Sanz, G; Sanz-Rosa, D; Valenciano, J, 2013)
"Pretreatment with propranolol and metoprolol improved survival to 90% and 100% respectively, compared with 60% in the ISO group, but did not reduce the incidence and extent of akinesis or the structural damage."1.40Functional and histological assessment of an experimental model of Takotsubo's cardiomyopathy. ( Dai, W; Kloner, RA; Sachdeva, J, 2014)
" Hepatic pharmacokinetic modelling was performed with a two-phase physiologically-based organ pharmacokinetic model with the vascular space and dispersion evaluated with the MID technique."1.38Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage. ( Crawford, DH; Fletcher, LM; Li, P; Roberts, MS; Robertson, TA; Weiss, M; Zhang, Q, 2012)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khwaja, S1
Mahmood, T1
Siddiqui, HH1
Ibanez, B3
Macaya, C1
Sánchez-Brunete, V2
Pizarro, G1
Fernández-Friera, L1
Mateos, A1
Fernández-Ortiz, A1
García-Ruiz, JM1
García-Álvarez, A1
Iñiguez, A1
Jiménez-Borreguero, J1
López-Romero, P1
Fernández-Jiménez, R1
Goicolea, J1
Ruiz-Mateos, B1
Bastante, T1
Arias, M1
Iglesias-Vázquez, JA1
Rodriguez, MD1
Escalera, N1
Acebal, C1
Cabrera, JA1
Valenciano, J1
Pérez de Prado, A1
Fernández-Campos, MJ1
Casado, I1
García-Rubira, JC1
García-Prieto, J1
Sanz-Rosa, D1
Cuellas, C1
Hernández-Antolín, R1
Albarrán, A1
Fernández-Vázquez, F1
de la Torre-Hernández, JM1
Pocock, S1
Sanz, G1
Fuster, V3
Sachdeva, J1
Dai, W1
Kloner, RA1
Roolvink, V1
Rasoul, S1
Ottervanger, JP1
Dambrink, JH1
Lipsic, E1
van der Horst, IC1
de Smet, B1
Kedhi, E1
Marcel Gosselink, AT1
Piek, JJ1
Van't Hof, AW1
Li, P1
Robertson, TA1
Zhang, Q1
Fletcher, LM1
Crawford, DH1
Weiss, M1
Roberts, MS1
Prat-González, S1
Speidl, WS1
Vilahur, G1
Pinero, A1
Cimmino, G1
García, MJ1
Sanz, J1
Badimon, JJ1
Kanda, T1
Inoue, M1
Suzuki, T1
Murata, K1
Vassanelli, C1
Menegatti, G1
Nidasio, GP1
Franceschini, L1
Cocco, C1
Rizzotti, P1
Gaba, DM1
Metz, S1
Maze, M1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial Infarction: a Double-Blind, Multicenter, Randomized, Placebo-Controlled Clinical Trial[NCT04912518]250 participants (Anticipated)Interventional2021-05-27Recruiting
ASSessing the Effect of Anti-IL-6 Treatment in Myocardial Infarction: The ASSAIL-MI Trial[NCT03004703]Phase 2200 participants (Actual)Interventional2017-03-16Completed
"Effect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion. The MEEffect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion (METOCARD-CNIC): A Randomized, Controlled Parallel-group, Observer-blinded Clinical Trial[NCT01311700]Phase 4221 participants (Actual)Interventional2010-11-30Completed
Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After ST-elevation Myocardial Infarction[NCT03516903]Phase 2/Phase 335 participants (Actual)Interventional2018-04-17Terminated (stopped due to Due to the COVID-19 pandemic. With a second wave just beginning, and considering that we are testing an immunosuppressant in patients with high risk for COVID-19 complications, we would not be able to re-start recruitment safely in the near future.)
Pharmacogenetic Study of Bisoprolol in Egyptian Patients With Acute Coronary Syndrome[NCT05536271]Phase 2127 participants (Actual)Interventional2021-09-01Completed
Potential Drug Interactions With Bisoprolol in Egyptian Patients With Acute Coronary Syndrome[NCT05536284]Phase 2128 participants (Actual)Interventional2021-09-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for metoprolol and Necrosis

ArticleYear
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
    Circulation, 2013, Oct-01, Volume: 128, Issue:14

    Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin

2013
Rationale and design of a double-blind, multicenter, randomized, placebo-controlled clinical trial of early administration of intravenous β-blockers in patients with ST-elevation myocardial infarction before primary percutaneous coronary intervention: EAR
    American heart journal, 2014, Volume: 168, Issue:5

    Topics: Administration, Intravenous; Adrenergic beta-Antagonists; Combined Modality Therapy; Double-Blind Me

2014

Other Studies

7 other studies available for metoprolol and Necrosis

ArticleYear
Effect of ethanolic extract of Cyperus rotundus L. against isoprenaline induced cardiotoxicity.
    Indian journal of experimental biology, 2016, Volume: 54, Issue:10

    Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarker

2016
Functional and histological assessment of an experimental model of Takotsubo's cardiomyopathy.
    Journal of the American Heart Association, 2014, Jun-23, Volume: 3, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Echo

2014
Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage.
    Pharmaceutical research, 2012, Volume: 29, Issue:6

    Topics: Adrenergic Antagonists; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti

2012
Early metoprolol administration before coronary reperfusion results in increased myocardial salvage: analysis of ischemic myocardium at risk using cardiac magnetic resonance.
    Circulation, 2007, Jun-12, Volume: 115, Issue:23

    Topics: Animals; Magnetic Resonance Imaging; Metoprolol; Myocardial Infarction; Myocardial Ischemia; Myocard

2007
Low-dose combination therapy with metoprolol and captopril for congestive heart failure in mice.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:5

    Topics: Animals; Captopril; Drug Therapy, Combination; Female; Heart Failure; Heart Ventricles; Metoprolol;

1993
Comparison of different pharmacological interventions on enzymatic parameters during acute myocardial infarction.
    Clinical biochemistry, 1987, Volume: 20, Issue:6

    Topics: Adult; Aged; Clinical Enzyme Tests; Creatine Kinase; Dipyridamole; Female; Heart; Heparin; Humans; I

1987
Postcountershock myocardial damage after pretreatment with adrenergic and calcium channel antagonists in halothane-anesthetized dogs.
    Anesthesiology, 1985, Volume: 62, Issue:5

    Topics: Anesthesia, Inhalation; Animals; Calcium Channel Blockers; Dogs; Electric Countershock; Female; Halo

1985