metoprolol has been researched along with Myocardial Ischemia in 89 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| " We compared the effect of metoprolol with placebo on mortality and cardiovascular morbidity rates in patients with diabetes mellitus who were beta-blocker naive, >or=40 years old, and undergoing noncardiac surgery." | 9.11 | The Diabetic Postoperative Mortality and Morbidity (DIPOM) trial: rationale and design of a multicenter, randomized, placebo-controlled, clinical trial of metoprolol for patients with diabetes mellitus who are undergoing major noncardiac surgery. ( Callesen, T; Gluud, C; Jensen, G; Juul, AB; Kofoed-Enevoldsen, A; Wetterslev, J, 2004) |
| "During dobutamine stress testing, metoprolol attenuates or eliminates evidence of myocardial ischemia." | 9.09 | Effect of intravenous metoprolol or intravenous metoprolol plus glucagon on dobutamine-induced myocardial ischemia. ( Ahlberg, AW; Heller, GV; Katten, D; Murthy, DR; Salloum, A; White, CM, 2000) |
| "Metoprolol (Met) is widely applied in the treatment of myocardial infarction and coronary heart disease in clinic." | 7.96 | Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia. ( Kou, J; Lai, Q; Li, F; Liu, Z; Wang, H; Yu, B; Yuan, G, 2020) |
| "Relative effectiveness of carvedilol and metoprolol succinate has never been compared in patients with heart failure (HF)." | 7.78 | Carvedilol or sustained-release metoprolol for congestive heart failure: a comparative effectiveness analysis. ( Aggarwal, V; Shore, S; Zolty, R, 2012) |
| "To compare efficacy and safety of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease (IHD) combined with type 2 diabetes." | 7.72 | [Clinical and metabolic effects of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease associated with type 2 diabetes]. ( Akhmedova, OO; Buval'tsev, VI; Gavrilov, IuV; Makolkin, VI; Petriĭ, VV, 2003) |
| "To describe a case of milrinone-associated tachycardia that was successfully treated with two beta-blockers." | 7.70 | Treatment of milrinone-associated tachycardia with beta-blockers. ( Alhashemi, JA; Hooper, J, 1998) |
| " Carvedilol low dose/high dose was shown to be at least as safe and well tolerated as metoprolol low dose/high dose both in younger and elderly patients." | 6.69 | Comparison of safety and efficacy of carvedilol and metoprolol in stable angina pectoris. ( Griffiths, M; Hauf-Zachariou, U; Holtbrügge, W; König, S; Lahiri, A; Pfarr, E; van der Does, R, 1999) |
| " The study medication was titrated over 6 weeks, the mean final dosage was 135 mg/day." | 6.69 | MIC trial: metoprolol in patients with mild to moderate heart failure: effects on ventricular function and cardiopulmonary exercise testing. ( Böhm, M; Darius, H; Genth-Zotz, S; Hanrath, P; Hartmann, D; Meyer, J; Sigmund, M; Treese, N; Waagstein, F; Zotz, RJ, 2000) |
| "Metoprolol is a widely used anti-ischemic drug with a relatively short half-life." | 6.68 | Comparison between metoprolol orally osmotic once daily and metoprolol two or three times daily in suppressing exercise-induced and daily myocardial ischemia. ( Barzilai, Y; Brunel, P; David, D; Gavish, A; Keren, A; Medina, A; Shatboon, D; Tzivoni, D, 1996) |
| "Nifedipine was administered to 20 patients (8 in group 1, and 12 in group 2)." | 6.67 | Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol. ( Andersen, PE; Egstrup, K, 1993) |
| "Whereas prior experiments in juvenile pigs had reported infarct size reduction by intravenous metoprolol early during myocardial ischaemia, two major clinical trials in patients with reperfused acute myocardial infarction were equivocal." | 5.69 | No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs. ( Heusch, G; Kleinbongard, P; Lieder, HR; Skyschally, A, 2023) |
| "Metoprolol can reduce the occurrence of perioperative cardiac events and postoperative tachycardia in the elderly esophageal cancer patients undergoing esophagectomy, and restrain the effects of tracheal intubation or extubation on heart rate and blood pressure." | 5.12 | [Beneficial effects of metoprolol on perioperative cardiac function of elderly esophageal cancer patients]. ( Huang, WQ; Lai, RC; Lin, WQ; Wang, XD; Xu, MX; Zeng, WA, 2006) |
| " We compared the effect of metoprolol with placebo on mortality and cardiovascular morbidity rates in patients with diabetes mellitus who were beta-blocker naive, >or=40 years old, and undergoing noncardiac surgery." | 5.11 | The Diabetic Postoperative Mortality and Morbidity (DIPOM) trial: rationale and design of a multicenter, randomized, placebo-controlled, clinical trial of metoprolol for patients with diabetes mellitus who are undergoing major noncardiac surgery. ( Callesen, T; Gluud, C; Jensen, G; Juul, AB; Kofoed-Enevoldsen, A; Wetterslev, J, 2004) |
| "The prognostic significance of ambulatory ischemia, alone and in relation to ischemia during exercise was assessed in 686 patients (475 men) with chronic stable angina pectoris taking part in the Angina Prognosis Study In Stockholm (APSIS), who had 24-hour ambulatory electrocardiographic registrations and exercise tests at baseline (n = 678) and after 1 month (n = 607) of double-blind treatment with metoprolol or verapamil." | 5.09 | Prognostic implications of ambulatory myocardial ischemia and arrhythmias and relations to ischemia on exercise in chronic stable angina pectoris (the Angina Prognosis Study in Stockholm [APSIS]). ( Björkander, I; Eriksson, SV; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N, 1999) |
| "During dobutamine stress testing, metoprolol attenuates or eliminates evidence of myocardial ischemia." | 5.09 | Effect of intravenous metoprolol or intravenous metoprolol plus glucagon on dobutamine-induced myocardial ischemia. ( Ahlberg, AW; Heller, GV; Katten, D; Murthy, DR; Salloum, A; White, CM, 2000) |
| "A randomized study was performed on 70 patients undergoing elective coronary bypass grafting to examine whether the combined infusion of the calcium channel blocker nifedipine (10 micrograms/kg per hour) and the beta 1-blocker metopropol (12 micrograms/kg per hour, n = 34) reduces the prevalence of perioperative myocardial ischemia and arrhythmias." | 5.08 | Comparison of perioperative myocardial protection with nifedipine versus nifedipine and metoprolol in patients undergoing elective coronary artery bypass grafting. ( Binder, TM; Podesser, BK; Schwarzacher, S; Seitelberger, R; Wolner, E; Zwoelfer, W, 1995) |
| "In a study of 48 patients with coronary artery disease and evidence of ischemia during exercise and daily life, metoprolol reduced the threshold of myocardial ischemia in a dose-dependent manner." | 5.08 | Effect of metoprolol in reducing myocardial ischemic threshold during exercise and during daily activity. ( Barzilai, Y; Brunel, P; David, D; Medina, A; Tzivoni, D, 1998) |
| "This study was conducted to determine whether rebound ischemia occurs during nitrate-free periods with intermittent cutaneous nitroglycerin therapy in patients with angina pectoris who are receiving background antianginal therapy." | 5.08 | Intermittent transdermal nitrates do not improve ischemia in patients taking beta-blockers or calcium antagonists: potential role of rebound ischemia during the nitrate-free period. ( Daxini, BV; Freedman, SB; Kelly, DT; Noyce, D, 1995) |
| "We conducted a randomised controlled trial to study the effects of metoprolol and diltiazem on the total ischaemic burden--sum of symptomatic and silent myocardial ischaemia, in 146 patients with stable angina pectoris." | 5.07 | Effect of metoprolol and diltiazem on the total ischaemic burden in patients with chronic stable angina: a randomized controlled trial. ( Ahuja, RC; Kumar, RR; Saran, RK; Sinha, N, 1993) |
| "A randomised study was performed on 70 patients undergoing elective coronary by-pass procedure to examine whether the combined, perioperative, 24-hour infusion of nifedipine and metoprolol reduces the incidence of perioperative myocardial ischemia and arrhythmias." | 5.07 | Perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary by-pass surgery. ( Binder, T; Huber, S; Peschl, F; Podesser, B; Schwarzacher, S; Seitelberger, R; Spatt, J; Wolner, E; Zwölfer, W, 1994) |
| "A randomized study was performed on 70 patients undergoing elective coronary bypass surgery to examine whether the combined, perioperative, 24-hour infusion of the calcium-channel blocker nifedipine (10 micrograms/kg/h) and the beta 1-blocker metoprolol (12 micrograms/kg/h) reduces the incidence of perioperative myocardial ischemia and arrhythmias (group NM, n = 34)." | 5.07 | Combined perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary bypass surgery. ( Binder, TM; Huber, S; Peschl, F; Podesser, B; Schwarzacher, S; Seitelberger, R; Spatt, J; Zwölfer, W, 1993) |
| "Metoprolol (Met) is widely applied in the treatment of myocardial infarction and coronary heart disease in clinic." | 3.96 | Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia. ( Kou, J; Lai, Q; Li, F; Liu, Z; Wang, H; Yu, B; Yuan, G, 2020) |
| "Relative effectiveness of carvedilol and metoprolol succinate has never been compared in patients with heart failure (HF)." | 3.78 | Carvedilol or sustained-release metoprolol for congestive heart failure: a comparative effectiveness analysis. ( Aggarwal, V; Shore, S; Zolty, R, 2012) |
| "To assess efficacy and safety of selective beta-adrenoblockers (BAB) metoprolol succinate and nebivolol in patients with arterial hypertension (AH) and/or IHD associated with bronchoobstructive syndrome (BOS)." | 3.74 | [Administration of cardioselective beta-adrenoblockers in patients with arterial hypertension and/or ischemic heart disease associated with bronchoobstructive syndrome]. ( Litvinova, IV; Mikolkin, VI; Ovcharenko, SI, 2007) |
| "To compare efficacy and safety of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease (IHD) combined with type 2 diabetes." | 3.72 | [Clinical and metabolic effects of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease associated with type 2 diabetes]. ( Akhmedova, OO; Buval'tsev, VI; Gavrilov, IuV; Makolkin, VI; Petriĭ, VV, 2003) |
| "To describe a case of milrinone-associated tachycardia that was successfully treated with two beta-blockers." | 3.70 | Treatment of milrinone-associated tachycardia with beta-blockers. ( Alhashemi, JA; Hooper, J, 1998) |
| "Carvedilol, a selective alpha1 and non-selective beta-adrenoceptor antagonist and antioxidant, has been shown to provide significant cardiac protection in animal models of myocardial ischemia." | 3.70 | Comparison of metoprolol and carvedilol pharmacology and cardioprotection in rabbit ischemia and reperfusion model. ( Arch, JR; Cheng, HY; Feuerstein, G; Hieble, JP; Liu, GL; Ma, XL; Ruffolo, RR; Yue, TL, 1998) |
| "Metoprolol treatment was initiated in 27 patients (group 1), meanwhile 19 patients could not take metoprolol due to diverse contraindications (group 2)." | 2.72 | Coronary angioplasty induced oxidative stress and its relation with metoprolol use and plasma homocysteine levels. ( Ciçek, D; Cin, VG; Kara, AA; Pekdemir, H; Tamer, L; Yildirim, H; Yurtdaş, M, 2006) |
| " Beta-blocker use at the 2 dosage levels was associated with significant improvement in survival compared with the nonuse of beta blockers (hazard ratios 0." | 2.71 | Effects of beta-blockers on implantable cardioverter defibrillator therapy and survival in the patients with ischemic cardiomyopathy (from the Multicenter Automatic Defibrillator Implantation Trial-II). ( Andrews, M; Brodine, WN; Daubert, JP; Hall, WJ; Hockstad, ES; Lee, JK; McNitt, S; Moss, AJ; Tung, RT; Zareba, W, 2005) |
| "Patients were divided into two groups: ischemic heart disease (IHD) and idiopathic dilated cardiomyopathy (DCM)." | 2.71 | Increased exercise ejection fraction and reversed remodeling after long-term treatment with metoprolol in congestive heart failure: a randomized, stratified, double-blind, placebo-controlled trial in mild to moderate heart failure due to ischemic or idiop ( Andersson, B; Böhm, M; Darius, M; Delius, W; Goss, F; Osterziel, KJ; Sigmund, M; Strömblad, O; Trenkwalder, SP; Waagstein, F; Wahlqvist, I, 2003) |
| "Myocardial ischemia was quantified with adenosine 201Tl tomography (SPECT) performed 4." | 2.69 | Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study. ( Dakik, HA; Farmer, JA; He, ZX; Kleiman, NS; Mahmarian, JJ; Pratt, CM; Verani, MS; Wendt, JA, 1998) |
| " Carvedilol low dose/high dose was shown to be at least as safe and well tolerated as metoprolol low dose/high dose both in younger and elderly patients." | 2.69 | Comparison of safety and efficacy of carvedilol and metoprolol in stable angina pectoris. ( Griffiths, M; Hauf-Zachariou, U; Holtbrügge, W; König, S; Lahiri, A; Pfarr, E; van der Does, R, 1999) |
| "Forty-five patients with congestive heart failure were studied with Holter recordings." | 2.69 | Potential risk of beta-blockade withdrawal in congestive heart failure due to abrupt autonomic changes. ( Andersson, B; Di Lenarda, A; Hjalmarson, A; Rundqvist, B; Sinagra, G; Tygesen, H; Waagstein, F; Wennerblom, B, 1999) |
| " The study medication was titrated over 6 weeks, the mean final dosage was 135 mg/day." | 2.69 | MIC trial: metoprolol in patients with mild to moderate heart failure: effects on ventricular function and cardiopulmonary exercise testing. ( Böhm, M; Darius, H; Genth-Zotz, S; Hanrath, P; Hartmann, D; Meyer, J; Sigmund, M; Treese, N; Waagstein, F; Zotz, RJ, 2000) |
| "Metoprolol is a widely used anti-ischemic drug with a relatively short half-life." | 2.68 | Comparison between metoprolol orally osmotic once daily and metoprolol two or three times daily in suppressing exercise-induced and daily myocardial ischemia. ( Barzilai, Y; Brunel, P; David, D; Gavish, A; Keren, A; Medina, A; Shatboon, D; Tzivoni, D, 1996) |
| "Treatment with metoprolol for two years after coronary artery bypass grafting did not significantly change exercise capacity or electrocardiographic signs of myocardial ischaemia." | 2.68 | Metoprolol treatment for two years after coronary bypass grafting: effects on exercise capacity and signs of myocardial ischaemia. ( Caidahl, K; Herlitz, J; Hjalmarson, A; Lurje, L; Sjöland, H, 1995) |
| "Nifedipine was administered to 20 patients (8 in group 1, and 12 in group 2)." | 2.67 | Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol. ( Andersen, PE; Egstrup, K, 1993) |
| "Atropine was given to patients on beta-blockers more often [(22/26) vs (6/26)] than to those off beta-blockers (P < 0." | 2.67 | Atropine increases the accuracy of dobutamine stress echocardiography in patients taking beta-blockers. ( Bellotti, P; Boersma, E; el-Said, ES; Fioretti, PM; Forster, T; McNeill, AJ; Poldermans, D; Roelandt, JR; Salustri, A, 1994) |
| "Metoprolol has proven its efficacy in reducing cardiovascular events and mortality in patients with hypertension and coronary heart disease in large clinical trials." | 2.42 | [Metoprolol CR/XL: advanced formulation of a classical beta-blocker]. ( Gudkov, KM; Kobalava, ZhD, 2003) |
| "Metoprolol can increase the VFT and decrease the excitation threshold of the ischemic myocardium in diabetic rats." | 1.37 | [Effects of metoprolol on electrophysiology of ischemic and anoxic myocardium in diabetic rats]. ( Chen, JM; He, L; Jin, HF; Shen, FR; Sun, GJ; Wang, ZJ; Zeng, WP; Zhong, C, 2011) |
| "Metoprolol treatment (60 mg/kg/day via gastric gavage) was started on the second day after surgery and continued until sacrifice at 6 weeks after myocardial infarction." | 1.31 | Metoprolol attenuates postischemic depressed myocardial function in papillary muscles isolated from normal and postinfarction rat hearts. ( Ding, B; Min, JY; Morgan, JP; Sullivan, MF; Wang, JF, 2001) |
| "In patients with ischemic heart disease, recurrences of VT or VF peaked in the morning." | 1.31 | Absence of a morning peak in ventricular tachycardia and fibrillation events in nonischemic heart disease: analysis of therapies by implantable cardioverter defibrillators. ( Aizawa, Y; Taneda, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 36 (40.45) | 18.2507 |
| 2000's | 35 (39.33) | 29.6817 |
| 2010's | 14 (15.73) | 24.3611 |
| 2020's | 4 (4.49) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C | 1 |
| Tian, J | 1 |
| He, Z | 1 |
| Xiong, W | 1 |
| He, Y | 1 |
| Liu, S | 1 |
| Kleinbongard, P | 1 |
| Lieder, HR | 1 |
| Skyschally, A | 1 |
| Heusch, G | 1 |
| Lai, Q | 1 |
| Yuan, G | 1 |
| Wang, H | 1 |
| Liu, Z | 1 |
| Kou, J | 1 |
| Yu, B | 1 |
| Li, F | 1 |
| Wade, C | 1 |
| Wells, JM | 1 |
| Le, DE | 1 |
| Pascotto, M | 1 |
| Leong-Poi, H | 1 |
| Sari, I | 1 |
| Micari, A | 1 |
| Kaul, S | 1 |
| Furuichi, Y | 1 |
| Sakamoto, A | 1 |
| Wojtczak, A | 1 |
| Wojtczak, M | 1 |
| Skrętkowicz, J | 1 |
| Galeeva, ZM | 1 |
| Galiavich, AS | 1 |
| Metzsch, C | 1 |
| Linnér, R | 1 |
| Steen, S | 1 |
| Liao, Q | 1 |
| Algotsson, L | 1 |
| Unuma, K | 1 |
| Shintani-Ishida, K | 1 |
| Yahagi, N | 1 |
| Tsushima, K | 1 |
| Shimosawa, T | 1 |
| Ueyama, T | 1 |
| Yoshida, K | 1 |
| Hayashi, H | 1 |
| McMurray, JJ | 1 |
| Ozova, EM | 1 |
| Kiiakbaev, GK | 1 |
| Kobalava, ZhD | 2 |
| Moiseev, VS | 1 |
| Fedorets, VN | 1 |
| Jin, HF | 1 |
| Zeng, WP | 1 |
| Shen, FR | 1 |
| Wang, ZJ | 1 |
| He, L | 1 |
| Sun, GJ | 1 |
| Chen, JM | 1 |
| Zhong, C | 1 |
| Sengul, C | 1 |
| Fotbolcu, H | 1 |
| Ozde, K | 1 |
| Duman, D | 1 |
| Kumar, S | 1 |
| Kaushik, S | 1 |
| Vaval, A | 1 |
| Zhao, Q | 1 |
| Lazar, JM | 1 |
| Grodman, R | 1 |
| Shore, S | 1 |
| Aggarwal, V | 1 |
| Zolty, R | 1 |
| Svistov, AS | 1 |
| Sukhov, VIu | 1 |
| Makiev, RG | 1 |
| Alanichev, AE | 1 |
| Makolkin, VI | 1 |
| Akhmedova, OO | 1 |
| Buval'tsev, VI | 1 |
| Gavrilov, IuV | 1 |
| Petriĭ, VV | 1 |
| Gudkov, KM | 1 |
| Waagstein, F | 4 |
| Strömblad, O | 1 |
| Andersson, B | 3 |
| Böhm, M | 2 |
| Darius, M | 1 |
| Delius, W | 1 |
| Goss, F | 1 |
| Osterziel, KJ | 1 |
| Sigmund, M | 2 |
| Trenkwalder, SP | 1 |
| Wahlqvist, I | 1 |
| Li, X | 1 |
| Jones, M | 1 |
| Wang, HF | 1 |
| Davies, CH | 1 |
| Swanson, JC | 1 |
| Hashimoto, I | 1 |
| Rusk, RA | 1 |
| Schindera, ST | 1 |
| Barber, BJ | 1 |
| Sahn, DJ | 1 |
| Juul, AB | 1 |
| Wetterslev, J | 1 |
| Kofoed-Enevoldsen, A | 1 |
| Callesen, T | 1 |
| Jensen, G | 1 |
| Gluud, C | 1 |
| Quintana, M | 1 |
| Gustafsson, T | 1 |
| Sundblad, P | 1 |
| Langanger, J | 1 |
| Cinquegrana, G | 1 |
| D'Aniello, L | 1 |
| Landi, M | 1 |
| Spinelli, L | 1 |
| Grande, G | 1 |
| De Prisco, F | 1 |
| Petretta, M | 1 |
| Green, P | 1 |
| Anshelevich, M | 1 |
| Talreja, A | 1 |
| Burcham, JL | 1 |
| Ravi, SM | 1 |
| Shirani, J | 1 |
| Le Jemtel, TH | 1 |
| Tereshchenko, SN | 1 |
| Kositsyna, IV | 1 |
| Dzhaiani, NA | 1 |
| Brodine, WN | 1 |
| Tung, RT | 1 |
| Lee, JK | 1 |
| Hockstad, ES | 1 |
| Moss, AJ | 1 |
| Zareba, W | 1 |
| Hall, WJ | 1 |
| Andrews, M | 1 |
| McNitt, S | 1 |
| Daubert, JP | 1 |
| Yilmaz, R | 1 |
| Demirbag, R | 1 |
| Ahmet, I | 1 |
| Lakatta, EG | 1 |
| Talan, MI | 1 |
| Cocco, G | 1 |
| Chu, D | 1 |
| Lai, RC | 1 |
| Xu, MX | 1 |
| Huang, WQ | 1 |
| Wang, XD | 1 |
| Zeng, WA | 1 |
| Lin, WQ | 1 |
| Liu, Y | 1 |
| Huang, CL | 1 |
| He, M | 1 |
| Zhang, LN | 1 |
| Cai, HW | 1 |
| Guo, QL | 1 |
| Ritchie, RH | 2 |
| Zeitz, CJ | 1 |
| Wuttke, RD | 1 |
| Hii, JT | 1 |
| Horowitz, JD | 2 |
| Ciçek, D | 1 |
| Tamer, L | 1 |
| Pekdemir, H | 1 |
| Cin, VG | 1 |
| Yildirim, H | 1 |
| Kara, AA | 1 |
| Yurtdaş, M | 1 |
| Baxter, AD | 1 |
| Kanji, S | 1 |
| Ibanez, B | 1 |
| Prat-González, S | 1 |
| Speidl, WS | 1 |
| Vilahur, G | 1 |
| Pinero, A | 1 |
| Cimmino, G | 1 |
| García, MJ | 1 |
| Fuster, V | 1 |
| Sanz, J | 1 |
| Badimon, JJ | 1 |
| Kiselev, AR | 1 |
| Gridnev, VI | 1 |
| Posnenkova, OM | 1 |
| Bespiatov, AB | 1 |
| Dovgalevskiĭ, PIa | 1 |
| Ponomarenko, VI | 1 |
| Prokhorov, MD | 1 |
| Kotel'nikova, EV | 1 |
| Ablad, B | 1 |
| Bjurö, T | 1 |
| Björkman, JA | 1 |
| Edström, T | 1 |
| Fox, K | 1 |
| Borer, JS | 1 |
| Camm, AJ | 1 |
| Danchin, N | 1 |
| Ferrari, R | 1 |
| Lopez Sendon, JL | 1 |
| Steg, PG | 1 |
| Tardif, JC | 1 |
| Tavazzi, L | 1 |
| Tendera, M | 1 |
| Ovcharenko, SI | 1 |
| Litvinova, IV | 1 |
| Mikolkin, VI | 1 |
| Lujan, HL | 1 |
| Dicarlo, SE | 1 |
| Podesser, BK | 1 |
| Schwarzacher, S | 3 |
| Zwoelfer, W | 1 |
| Binder, TM | 2 |
| Wolner, E | 2 |
| Seitelberger, R | 3 |
| Sjöland, H | 1 |
| Caidahl, K | 2 |
| Lurje, L | 1 |
| Hjalmarson, A | 2 |
| Herlitz, J | 1 |
| V'iuchnova, ES | 1 |
| Maev, IV | 1 |
| Merzlikin, LA | 1 |
| Podesser, B | 2 |
| Zwölfer, W | 2 |
| Binder, T | 1 |
| Spatt, J | 2 |
| Peschl, F | 2 |
| Huber, S | 2 |
| Freedman, SB | 1 |
| Daxini, BV | 1 |
| Noyce, D | 1 |
| Kelly, DT | 1 |
| Fioretti, PM | 1 |
| Poldermans, D | 1 |
| Salustri, A | 1 |
| Forster, T | 1 |
| Bellotti, P | 1 |
| Boersma, E | 1 |
| McNeill, AJ | 1 |
| el-Said, ES | 1 |
| Roelandt, JR | 1 |
| Kobayashi, S | 1 |
| Tadokoro, H | 1 |
| Rydén, L | 1 |
| Sjöquist, PO | 1 |
| Haendchen, RV | 1 |
| Corday, E | 1 |
| Peters, RW | 1 |
| Kim, HJ | 1 |
| Buser, GA | 1 |
| Gold, MR | 1 |
| Ahuja, RC | 1 |
| Sinha, N | 1 |
| Kumar, RR | 1 |
| Saran, RK | 2 |
| Egstrup, K | 1 |
| Andersen, PE | 1 |
| Zhang, YI | 1 |
| Singh, N | 1 |
| Mironov, D | 1 |
| Goodman, S | 1 |
| Morgan, CD | 1 |
| Langer, A | 1 |
| Rosenberg, J | 2 |
| Overgaard, H | 2 |
| Andersen, M | 1 |
| Rasmussen, V | 2 |
| Schulze, S | 2 |
| Cheng, DC | 1 |
| Jiang, MT | 1 |
| Asokumar, B | 1 |
| Boylen, P | 1 |
| Sandler, A | 1 |
| Bech, J | 1 |
| Madsen, JK | 1 |
| Kelbaek, H | 1 |
| Hvid-Jacobsen, K | 1 |
| Skagen, K | 1 |
| Tzivoni, D | 2 |
| Medina, A | 2 |
| David, D | 2 |
| Barzilai, Y | 2 |
| Gavish, A | 1 |
| Shatboon, D | 1 |
| Keren, A | 1 |
| Brunel, P | 2 |
| Gonsorcík, J | 1 |
| Szakács, M | 1 |
| Palko, S | 1 |
| Mydlík, M | 1 |
| Bristow, MR | 1 |
| Abraham, WT | 1 |
| Yoshikawa, T | 1 |
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| Felix, SB | 2 |
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| Baumann, G | 2 |
| Anderson, MM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Effect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion. The MEEffect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion (METOCARD-CNIC): A Randomized, Controlled Parallel-group, Observer-blinded Clinical Trial[NCT01311700] | Phase 4 | 221 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
| A Single Centre, Retrospective Cohort Study on Post Analysis on the Link Between the Clinical Heart Rate and Outcomes During PCI[NCT02351674] | 15,000 participants (Anticipated) | Observational | 2015-01-31 | Not yet recruiting | |||
| Heart Rate Lowering Efficacy and Respiratory Safety of Ivabradine in Patients With Obstructive Airway Disease[NCT01365286] | Phase 4 | 40 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| "PGDT With the Hypotension Prediction Index to Reduce the Number and Duration of Intraoperative Hypotension and the Incidence of Renal Failure in Patients Undergoing Lung Surgery"[NCT04149314] | 142 participants (Actual) | Interventional | 2019-11-20 | Completed | |||
| Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension[NCT05593055] | Phase 4 | 75 participants (Anticipated) | Interventional | 2023-08-25 | Recruiting | ||
| Effects of Long Term Adaptive Servo Ventilation Therapy on Myocardial Energetics and Sympathetic Nerve Function in Heart Failure and Sleep Apnea. The AMEND Sub-study[NCT02116140] | 60 participants (Anticipated) | Interventional | 2012-07-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for metoprolol and Myocardial Ischemia
| Article | Year |
|---|---|
Practical recommendations for the use of beta-blockers in chronic obstructive pulmonary disease.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Heart Failure; Humans; Metoprolol; Myocardial Isc | 2020 |
[Perioperative cardiovascular evaluation and management for noncardiac surgery].
Topics: Adrenergic beta-Antagonists; Anesthesia; Atenolol; Bisoprolol; Fatty Acids, Monounsaturated; Fluvast | 2014 |
[Metoprolol CR/XL: advanced formulation of a classical beta-blocker].
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Contraindications; Heart Failure; Humans; Hyperte | 2003 |
[The place of metoprolol in the treatment of ischemic heart disease].
Topics: Adrenergic beta-Antagonists; Humans; Metoprolol; Myocardial Ischemia; Randomized Controlled Trials a | 2005 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Thyrotoxicosis, unstable angina and normal coronary angiogram.
Topics: Angina, Unstable; Anti-Arrhythmia Agents; Chest Pain; Combined Modality Therapy; Coronary Angiograph | 1999 |
39 trials available for metoprolol and Myocardial Ischemia
| Article | Year |
|---|---|
No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs.
Topics: Animals; Metoprolol; Myocardial Infarction; Myocardial Ischemia; Myocardium; Swine; Swine, Miniature | 2023 |
[Efficacy and tolerability of metoprolol retard in the treatment of patients with arterial hypertension and ischemic heart disease combined with type 2 diabetes mellitus].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Diabetes Mellitus, Type 2; Female; Humans; Hyp | 2009 |
[Effect of carvedilol and metoprolol R administered with or without atorvastatin on elastic properties of vascular wall and parameters of inflammation in patients with chronic heart failure of ischemic origin].
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Aged; Anticholesteremic Agents; Arterioles; Atorvasta | 2011 |
Increased exercise ejection fraction and reversed remodeling after long-term treatment with metoprolol in congestive heart failure: a randomized, stratified, double-blind, placebo-controlled trial in mild to moderate heart failure due to ischemic or idiop
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Double-Blind Method; Exercise; Exercise Test; | 2003 |
The Diabetic Postoperative Mortality and Morbidity (DIPOM) trial: rationale and design of a multicenter, randomized, placebo-controlled, clinical trial of metoprolol for patients with diabetes mellitus who are undergoing major noncardiac surgery.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Diabetes Complications; Diabetes Mellit | 2004 |
Effects of different degrees of sympathetic antagonism on cytokine network in patients with ischemic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Echocardiography; Fema | 2005 |
Effects of beta-blockers on implantable cardioverter defibrillator therapy and survival in the patients with ischemic cardiomyopathy (from the Multicenter Automatic Defibrillator Implantation Trial-II).
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Carbazoles; Carvedilol; Defibrillators, Implantable; Fe | 2005 |
[Beneficial effects of metoprolol on perioperative cardiac function of elderly esophageal cancer patients].
Topics: Aged; Atrial Fibrillation; Blood Pressure; Cardiotonic Agents; Esophageal Neoplasms; Esophagectomy; | 2006 |
[Influences of perioperative metoprolol on hemodynamics and myocardial ischaemia in elderly patients undergoing noncardiac surgery].
Topics: Adrenergic beta-Antagonists; Aged; Anesthesia, Intravenous; Electrocardiography; Esophagectomy; Fema | 2006 |
Coronary angioplasty induced oxidative stress and its relation with metoprolol use and plasma homocysteine levels.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angioplasty, Balloon, Coronary; Female; Homocysteine; Huma | 2006 |
[Assessment of dynamics of the autonomic cardiovascular system regulation based on low-frequency rhythm synchronization in patients with ischemic heart diseases complicated by myocardial infarction treated with metoprolol].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Autonomic Nervous System; Coronary Circulation; Electrocar | 2007 |
Prevention of ventricular fibrillation requires central beta-adrenoceptor blockade in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Baroreflex; Blood Pressure; Central Nervous System; | 2007 |
Comparison of perioperative myocardial protection with nifedipine versus nifedipine and metoprolol in patients undergoing elective coronary artery bypass grafting.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Artery Bypass; | 1995 |
Metoprolol treatment for two years after coronary bypass grafting: effects on exercise capacity and signs of myocardial ischaemia.
Topics: Adrenergic beta-Antagonists; Aged; Coronary Artery Bypass; Double-Blind Method; Electrocardiography; | 1995 |
Perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary by-pass surgery.
Topics: Arrhythmias, Cardiac; Coronary Artery Bypass; Creatine Kinase; Electrocardiography, Ambulatory; Enda | 1994 |
Intermittent transdermal nitrates do not improve ischemia in patients taking beta-blockers or calcium antagonists: potential role of rebound ischemia during the nitrate-free period.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel B | 1995 |
Recovery from left ventricular asynergy in ischemic cardiomyopathy following long-term beta blockade treatment.
Topics: Aged; Echocardiography; Heart Failure; Humans; Male; Metoprolol; Middle Aged; Myocardial Contraction | 1994 |
Atropine increases the accuracy of dobutamine stress echocardiography in patients taking beta-blockers.
Topics: Aged; Angina Pectoris; Atropine; Dobutamine; Drug Synergism; Echocardiography; Electrocardiography; | 1994 |
Effect of metoprolol and diltiazem on the total ischaemic burden in patients with chronic stable angina: a randomized controlled trial.
Topics: Angina Pectoris; Diltiazem; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Huma | 1993 |
Combined perioperative infusion of nifedipine and metoprolol provides antiischemic and antiarrhythmic protection in patients undergoing elective aortocoronary bypass surgery.
Topics: Aged; Arrhythmias, Cardiac; Coronary Artery Bypass; Drug Therapy, Combination; Electrocardiography, | 1993 |
Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol.
Topics: Angina Pectoris; Collateral Circulation; Coronary Angiography; Coronary Circulation; Double-Blind Me | 1993 |
Postextrasystolic potentiation in patients with ischaemic heart disease: influence of inotropic agents.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiac Complexes, Premature; Cardiotonic Agents; Female; | 1995 |
Treatment of silent ischemia in unstable angina: a randomized comparison of sustained-release verapamil versus metoprolol.
Topics: Adrenergic beta-Antagonists; Aged; Angina, Unstable; Calcium Channel Blockers; Delayed-Action Prepar | 1995 |
Double blind randomised controlled trial of effect of metoprolol on myocardial ischaemia during endoscopic cholangiopancreatography.
Topics: Adrenergic beta-Agonists; Cholangiopancreatography, Endoscopic Retrograde; Double-Blind Method; Elec | 1996 |
Metoprolol abolishes exercise-induced left ventricular dysfunction in patients with silent ischemia.
Topics: Adrenergic beta-Antagonists; Cross-Over Studies; Double-Blind Method; Electrocardiography; Exercise; | 1996 |
Comparison between metoprolol orally osmotic once daily and metoprolol two or three times daily in suppressing exercise-induced and daily myocardial ischemia.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Dose-Response Relationship, Drug; Do | 1996 |
Second- and third-generation beta-blocking drugs in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiac Output, Low; Cardiomyopathy, Dilated; | 1997 |
[Metoprolol prevents myocardial ischemia during endoscopic retrograde cholangiopancreatography].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Cholangiopancreatography, Endoscop | 1997 |
Effect of race in the response to metoprolol in patients with congestive heart failure secondary to idiopathic dilated or ischemic cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathy, Dilated; Female; Heart Failure; Hemodynami | 1997 |
Effect of metoprolol in reducing myocardial ischemic threshold during exercise and during daily activity.
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Blood Pressure; Dose-Response Relationship, | 1998 |
Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study.
Topics: Adrenergic beta-Antagonists; Adult; Angioplasty, Balloon, Coronary; Diltiazem; Female; Humans; Isoso | 1998 |
Comparison of safety and efficacy of carvedilol and metoprolol in stable angina pectoris.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Age Factors; Aged; Angina Pectoris; Antio | 1999 |
Potential risk of beta-blockade withdrawal in congestive heart failure due to abrupt autonomic changes.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Electrocardiography, Ambulatory; Female; Follo | 1999 |
Prognostic implications of ambulatory myocardial ischemia and arrhythmias and relations to ischemia on exercise in chronic stable angina pectoris (the Angina Prognosis Study in Stockholm [APSIS]).
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Elect | 1999 |
Effects of metoprolol CR in patients with ischemic and dilated cardiomyopathy : the randomized evaluation of strategies for left ventricular dysfunction pilot study.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Delayed-Action Preparations; Dopamine; Double- | 2000 |
MIC trial: metoprolol in patients with mild to moderate heart failure: effects on ventricular function and cardiopulmonary exercise testing.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiac Volume; Cardiomyopathy, Dilated; Double-Blind Meth | 2000 |
The effects of beta(1)-blockade on oxidative metabolism and the metabolic cost of ventricular work in patients with left ventricular dysfunction: A double-blind, placebo-controlled, positron-emission tomography study.
Topics: Acetates; Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbon Radioisotopes; Cardiomyopathies; | 2000 |
The effects of beta(1)-blockade on oxidative metabolism and the metabolic cost of ventricular work in patients with left ventricular dysfunction: A double-blind, placebo-controlled, positron-emission tomography study.
Topics: Acetates; Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbon Radioisotopes; Cardiomyopathies; | 2000 |
The effects of beta(1)-blockade on oxidative metabolism and the metabolic cost of ventricular work in patients with left ventricular dysfunction: A double-blind, placebo-controlled, positron-emission tomography study.
Topics: Acetates; Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbon Radioisotopes; Cardiomyopathies; | 2000 |
The effects of beta(1)-blockade on oxidative metabolism and the metabolic cost of ventricular work in patients with left ventricular dysfunction: A double-blind, placebo-controlled, positron-emission tomography study.
Topics: Acetates; Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbon Radioisotopes; Cardiomyopathies; | 2000 |
Effect of intravenous metoprolol or intravenous metoprolol plus glucagon on dobutamine-induced myocardial ischemia.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Dobutamine; Drug Therap | 2000 |
Silent ischemic interval on exercise test is a predictor of response to drug therapy: a randomized crossover trial of metoprolol versus diltiazem in stable angina.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Cross-Over Stud | 2001 |
44 other studies available for metoprolol and Myocardial Ischemia
| Article | Year |
|---|---|
Identified Three Interferon Induced Proteins as Novel Biomarkers of Human Ischemic Cardiomyopathy.
Topics: Animals; Apoptosis Regulatory Proteins; Biomarkers; Cardiomyopathies; Disease Models, Animal; Gene R | 2021 |
Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Male; Metabolomics; Metoprolol; Mice; Mice, Inb | 2020 |
Anti-inflammatory and pro-angiogenic effects of beta blockers in a canine model of chronic ischemic cardiomyopathy: comparison between carvedilol and metoprolol.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Dogs; Echocardiography; Heart; Immunoh | 2013 |
The relationship between plasma concentration of metoprolol and CYP2D6 genotype in patients with ischemic heart disease.
Topics: Adult; Aged; Aged, 80 and over; Alleles; Cytochrome P-450 CYP2D6; Female; Genotype; Humans; Male; Me | 2014 |
Levosimendan cardioprotection in acutely beta-1 adrenergic receptor blocked open chest pigs.
Topics: Adrenergic beta-Antagonists; Animals; Cardiotonic Agents; Clinical Protocols; Female; Glucose; Glyce | 2010 |
Restraint stress induces connexin-43 translocation via α-adrenoceptors in rat heart.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Connexin 4 | 2010 |
Does remodeling of gap junctions and connexin expression contribute to arrhythmogenesis? Study in an immobilization rat model.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Animals; Arrhythmia | 2010 |
Heart failure: acute ischemic events in HF--should we include sudden death?
Topics: Adrenergic beta-1 Receptor Antagonists; Antihypertensive Agents; Benzopyrans; Death, Sudden, Cardiac | 2011 |
[Ischemic heart disease in elderly patients of behavioral type A (psychosocial and clinic functional changes, possibilities for correction)].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Anti-Anxiety Agents; Behavioral Symptoms; Benzodiaz | 2011 |
[Effects of metoprolol on electrophysiology of ischemic and anoxic myocardium in diabetic rats].
Topics: Animals; Diabetes Mellitus, Experimental; Heart; Male; Metoprolol; Myocardial Ischemia; Nerve Growth | 2011 |
Multiple coronary cameral fistulae: a rare anomaly and cause of ischaemia.
Topics: Aged, 80 and over; Angina Pectoris; Antihypertensive Agents; Coronary Angiography; Coronary Vessel A | 2012 |
Resolution of ischemia with β-blocker in a patient with anomalous right coronary artery.
Topics: Adrenergic beta-1 Receptor Antagonists; Chest Pain; Coronary Vessel Anomalies; Humans; Male; Metopro | 2011 |
Carvedilol or sustained-release metoprolol for congestive heart failure: a comparative effectiveness analysis.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathies; Carvedilol; Cohort Studies; Delayed-Actio | 2012 |
[Use of SPECT-scanning of the heart in estimating of influence of drugs of the background therapy of ischemic heart disease on myocardial perfusion].
Topics: Amlodipine; Antihypertensive Agents; Blood Flow Velocity; Cardiac-Gated Single-Photon Emission Compu | 2012 |
[Clinical and metabolic effects of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease associated with type 2 diabetes].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Benzopyrans; Carbohydrate Met | 2003 |
Strain rate acceleration yields a better index for evaluating left ventricular contractile function as compared with tissue velocity acceleration during isovolumic contraction time: an in vivo study.
Topics: Animals; Cardiac Output; Cardiotonic Agents; Dobutamine; Echocardiography, Doppler; Heart Ventricles | 2003 |
The effects of heart rate on myocardial velocity and atrio-ventricular displacement during exercise with and without beta-blockade: a tissue Doppler echocardiographic study.
Topics: Adrenergic beta-Antagonists; Adult; Atrial Function, Left; Echocardiography, Doppler, Color; Echocar | 2005 |
Long-term effects of carvedilol or metoprolol on left ventricular function in ischemic and nonischemic cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; Cardiomyopathy, Dilated; Ca | 2005 |
Systolic compression of anomalous large septal branch: an unusual cause of myocardial ischemia.
Topics: Adrenergic beta-Antagonists; Adult; Coronary Angiography; Coronary Stenosis; Exercise Test; Heart Se | 2005 |
Pharmacological stimulation of beta2-adrenergic receptors (beta2AR) enhances therapeutic effectiveness of beta1AR blockade in rodent dilated ischemic cardiomyopathy.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 2005 |
The anti-ischemic effect of metoprolol in patients with chronic angina pectoris is gender-specific.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Blood Pressure; Chronic Disease; Exercise Test; | 2006 |
Attenuation of the negative inotropic effects of metoprolol at short cycle lengths in humans: comparison with sotalol and verapamil.
Topics: Aged; Anti-Arrhythmia Agents; Cardiac Catheterization; Cardiac Pacing, Artificial; Female; Hemodynam | 2006 |
Protocol implementation in anesthesia: beta-blockade in non-cardiac surgery patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Clinical Protocols; Humans; Intensive C | 2007 |
Early metoprolol administration before coronary reperfusion results in increased myocardial salvage: analysis of ischemic myocardium at risk using cardiac magnetic resonance.
Topics: Animals; Magnetic Resonance Imaging; Metoprolol; Myocardial Infarction; Myocardial Ischemia; Myocard | 2007 |
[Administration of cardioselective beta-adrenoblockers in patients with arterial hypertension and/or ischemic heart disease associated with bronchoobstructive syndrome].
Topics: Adrenergic beta-Antagonists; Asthma; Benzopyrans; Comorbidity; Drug Administration Schedule; Ethanol | 2007 |
Sex differences to myocardial ischemia and beta-adrenergic receptor blockade in conscious rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cardia | 2008 |
[The correction of the hemodynamic disorders in patients with IHD complicated by intraventricular blocks by using beta-adrenergic agents].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Bundle-Branch Block; Drug Evaluation; | 1995 |
Local beta-adrenergic blockade does not reduce infarct size after coronary occlusion and reperfusion: a study of coronary venous retroinfusion of metoprolol.
Topics: Adrenergic beta-Antagonists; Animals; Coronary Vessels; Female; Hemodynamics; Infusions, Intravenous | 1993 |
Ischemically mediated sustained monomorphic ventricular tachycardia. Resolution with anti-ischemic therapy.
Topics: Coronary Angiography; Diltiazem; Drug Therapy, Combination; Electrocardiography; Humans; Isosorbide | 1993 |
Comparison of nifedipine and metoprolol on collateral coronary blood flow in a swine model of chronic coronary obstruction and acute ischaemia during isoflurane anaesthesia.
Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Calcium Channel Blockers; Chronic Dis | 1996 |
[Pharmacotherapy of silent myocardial ischemia in patients on hemodialysis].
Topics: Adrenergic beta-Agonists; Adult; Aged; Calcium Channel Blockers; Female; Humans; Kidney Failure, Chr | 1996 |
Release of a stable cardiodepressant mediator after myocardial ischaemia during reperfusion.
Topics: Adenosine Deaminase; Adrenergic beta-Antagonists; Animals; Autacoids; Catalase; Depression, Chemical | 1997 |
Treatment of milrinone-associated tachycardia with beta-blockers.
Topics: Adrenergic beta-Antagonists; Aged; Anesthesia, Epidural; Anesthesia, General; Anti-Arrhythmia Agents | 1998 |
Beta-blocker in acute coronary insufficiency.
Topics: Acute Disease; Adrenergic beta-Antagonists; Electrocardiography; Female; Humans; Metoprolol; Middle | 1997 |
Comparison of metoprolol and carvedilol pharmacology and cardioprotection in rabbit ischemia and reperfusion model.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Blood Pressure; Ca | 1998 |
Comparative effects of carvedilol and metoprolol on cardiac ischemia-reperfusion injury.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; L-La | 1998 |
Cardiodepressant mediators are released after myocardial ischaemia: modulation by catecholamines and adenosine.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Catecholamines; Chromatography, High Pressure Liqui | 1999 |
Hypotension in patients with coronary disease: can profound hypotensive events cause myocardial ischaemic events?
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Blood Pressure Monitoring, Amb | 1999 |
Are there differences between vasodilating and nonvasodilating beta-blockers in patients with heart failure? Do patients with ischemic heart disease benefit to the same degree?
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Female; Heart Failure; Hospitalization; Humans; | 2000 |
Angerlike behavioral state potentiates myocardial ischemia-induced T-wave alternans in canines.
Topics: Adrenergic beta-Antagonists; Anger; Animals; Arousal; Blood Pressure; Death, Sudden, Cardiac; Diseas | 2001 |
Metoprolol attenuates postischemic depressed myocardial function in papillary muscles isolated from normal and postinfarction rat hearts.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPase | 2001 |
Absence of a morning peak in ventricular tachycardia and fibrillation events in nonischemic heart disease: analysis of therapies by implantable cardioverter defibrillators.
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Circadian Rhythm; Defibrillators, Implantable; Female | 2001 |
Dobutamine stress echocardiography for the detection of myocardial viability in patients with left ventricular dysfunction taking beta blockers: accuracy and optimal dose.
Topics: Adrenergic beta-Antagonists; Atenolol; Cardiotonic Agents; Chronic Disease; Coronary Artery Bypass; | 2002 |
Effects of the serotonin-antagonist ketanserin on the function of ischaemic and normally perfused myocardium and modification by beta-1-blockade in anaesthetized normotensive dogs.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Coronary Circulation; Dogs; Female; Heart; Hea | 1992 |