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metoprolol and Kidney Diseases

metoprolol has been researched along with Kidney Diseases in 18 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to compare cardiovascular and renal events in patients with hypertension receiving the angiotensin II-receptor blocker valsartan versus those receiving the angiotensin-converting-enzyme lisinopril or the beta-blocker metoprolol succinate in an extended-release formulation."7.74Valsartan versus lisinopril or extended-release metoprolol in preventing cardiovascular and renal events in patients with hypertension. ( Delea, TE; Frech-Tamas, F; Moynahan, A; Oster, G; Taneja, C; Thomas, SK, 2007)
" We therefore investigated the influence of CYP2D6 polymorphism on steady-state plasma concentrations and apparent oral clearance of metoprolol in patients with cardiovascular diseases."5.12The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients. ( Ismail, R; Teh, LK, 2006)
"The African American Study of Kidney Disease and Hypertension was a multicenter trial comparing the effects of 2 levels of blood pressure control (usual or low goal) and initial therapy with metoprolol, ramipril, or amlodipine."5.12Quality of life in the African American Study of Kidney Disease and Hypertension: effects of blood pressure management. ( Gadegbeku, CA; Greene, T; Hall, Y; Jones, K; Kusek, JW; Lash, JP; Sika, M; Unruh, M; Wang, X, 2006)
"The objective of this study was to compare cardiovascular and renal events in patients with hypertension receiving the angiotensin II-receptor blocker valsartan versus those receiving the angiotensin-converting-enzyme lisinopril or the beta-blocker metoprolol succinate in an extended-release formulation."3.74Valsartan versus lisinopril or extended-release metoprolol in preventing cardiovascular and renal events in patients with hypertension. ( Delea, TE; Frech-Tamas, F; Moynahan, A; Oster, G; Taneja, C; Thomas, SK, 2007)
" The terminal plasma half-life (t1/2) on day 29 was 22 hours and systemic clearance was 490 mL/min on day 1 and 434 mL/min on day 29 (NS)."1.28Acute and steady-state pharmacokinetics and antihypertensive effects of felodipine in patients with normal and impaired renal function. ( Aberg, J; Gelin, A; Karlberg, BE; Larsson, R; Regårdh, CG, 1990)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19903 (16.67)18.7374
1990's2 (11.11)18.2507
2000's6 (33.33)29.6817
2010's7 (38.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avdeef, A1
Tam, KY1
Akgüllü, Ç1
Eryılmaz, U1
Güngör, H1
Huyut, A1
Zencir, C1
Hekim, T1
Ito, H1
Nagatomo, Y1
Kohno, T1
Anzai, T1
Meguro, T1
Ogawa, S1
Yoshikawa, T1
Davis, EM1
Appel, LJ1
Wang, X2
Greene, T2
Astor, BC1
Rahman, M1
Toto, R1
Lipkowitz, MS1
Pogue, VA1
Wright, JT1
Chobanian, AV1
El-Gowilly, SM1
Avci, E1
Yeşil, M1
Bayata, S1
Postaci, N1
Arikan, E1
Cirit, M1
Dorne, JL1
Walton, K1
Slob, W1
Renwick, AG1
Ismail, R1
Teh, LK1
Lash, JP1
Gadegbeku, CA1
Hall, Y1
Jones, K1
Kusek, JW1
Sika, M1
Unruh, M1
Fomin, VV1
Safonov, VV1
Kozlovskaia, NL1
Moiseev, SV1
Osipenko, VI1
Tironishvili, OI1
Almquist, T1
Forslund, L1
Rehnqvist, N1
Hjemdahl, P1
Delea, TE1
Taneja, C1
Moynahan, A1
Thomas, SK1
Frech-Tamas, F1
Oster, G1
Coevoet, B1
Lambrey, G1
de Frémont, JF1
Hardin, JM1
Desplan, C1
Calmette, C1
Makdassi, R1
Andrejak, M1
Moukhtar, MS1
Fournier, A1
Kuhn, U1
Kuhn, W1
Grospietsch, G1
Engelmann, A1
Girndt, J1
Larsson, R1
Karlberg, BE1
Gelin, A1
Aberg, J1
Regårdh, CG1
Lloyd, P1
John, VA1
Signy, M1
Smith, SE1
Rambausek, M1
Ritz, E1
Mall, G1
Mehls, O1
Katus, H1

Trials

5 trials available for metoprolol and Kidney Diseases

ArticleYear
Limitations of analyses based on achieved blood pressure: lessons from the African American study of kidney disease and hypertension trial.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:6

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Female;

2011
The role of nebivolol in the prevention of contrast-induced nephropathy in patients with renal dysfunction.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2011, Volume: 11, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Benzopyrans; Contrast Media; Coronary Angiography; Coronary Artery D

2011
The relevance of CYP2D6 genetic polymorphism on chronic metoprolol therapy in cardiovascular patients.
    Journal of clinical pharmacy and therapeutics, 2006, Volume: 31, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Antihypertensive Agents; Cardiovascular Dise

2006
Quality of life in the African American Study of Kidney Disease and Hypertension: effects of blood pressure management.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 47, Issue:6

    Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Black or African American; Blood Press

2006
Prognostic implications of renal dysfunction in patients with stable angina pectoris.
    Journal of internal medicine, 2006, Volume: 260, Issue:6

    Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Disease

2006

Other Studies

13 other studies available for metoprolol and Kidney Diseases

ArticleYear
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological

2010
A clinical study about contrast nephropathy: risk factors and the role of beta blockers.
    Anatolian journal of cardiology, 2015, Volume: 15, Issue:3

    Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Contrast Media; Cross-Sectional Studies; Female

2015
Differential effects of carvedilol and metoprolol on renal function in patients with heart failure.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:8

    Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Carbazoles; Carvedilol; Drug Evaluation; Female; Glome

2010
Mixed messages on blood pressure goals.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Glomerular Filtratio

2011
Metoprolol ameliorates cyclosporine a-induced hypertension and nephrotoxicity in rats.
    Journal of cardiovascular pharmacology, 2011, Volume: 58, Issue:6

    Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Antioxidants; Blood Pressure; Carbachol; Cyclospori

2011
Human variability in polymorphic CYP2D6 metabolism: is the kinetic default uncertainty factor adequate?
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:11

    Topics: Adult; Aged; Aging; Benzhydryl Compounds; Cresols; Cyclohexanols; Cytochrome P-450 CYP2D6; Debrisoqu

2002
[Ischemic disease of the kidneys in a patient with morbid obesity: characteristics of the course and diagnostic policy].
    Terapevticheskii arkhiv, 2006, Volume: 78, Issue:5

    Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Diagnosis, Differential; Health Policy; Human

2006
Valsartan versus lisinopril or extended-release metoprolol in preventing cardiovascular and renal events in patients with hypertension.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2007, Jun-01, Volume: 64, Issue:11

    Topics: Antihypertensive Agents; Cardiovascular Diseases; Delayed-Action Preparations; Female; Humans; Hyper

2007
[Evidence, in uremic man, of the role of beta 2 adrenergic receptors in the secretion of parathyroid hormone and calcitonin (author's transl)].
    Nephrologie, 1980, Volume: 1, Issue:1

    Topics: Adult; Calcitonin; Female; Heart Rate; Humans; Kidney Diseases; Male; Metoprolol; Parathyroid Hormon

1980
[The effect of metoprolol on fenoterol-induced kidney function disorders].
    Geburtshilfe und Frauenheilkunde, 1983, Volume: 43 Suppl 1

    Topics: Animals; Creatinine; Electrolytes; Ethanolamines; Female; Fenoterol; Hematocrit; Hemoglobins; Kidney

1983
Acute and steady-state pharmacokinetics and antihypertensive effects of felodipine in patients with normal and impaired renal function.
    Journal of clinical pharmacology, 1990, Volume: 30, Issue:11

    Topics: Adult; Aged; Biological Availability; Blood Pressure; Felodipine; Female; Furosemide; Glomerular Fil

1990
The effect of impaired renal function on the pharmacokinetics of metoprolol after single administration of a 14/190 metoprolol OROS system.
    American heart journal, 1990, Volume: 120, Issue:2

    Topics: Administration, Oral; Delayed-Action Preparations; Humans; Kidney Diseases; Male; Metoprolol; Osmola

1990
Myocardial hypertrophy in rats with renal insufficiency.
    Kidney international, 1985, Volume: 28, Issue:5

    Topics: Adenosine Triphosphatases; Animals; Blood Pressure; Blood Transfusion; Calcium; Cardiomegaly; Hydral

1985