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metoprolol and Intraocular Pressure

metoprolol has been researched along with Intraocular Pressure in 22 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"The selective beta-1 blocker Metoprolol was tested for a period of one month in a double-blind trial involving 36 patients with open-angle glaucoma or intraocular hypertension in whom the substance was applied twice daily to the eye in concentrations of 1, 2, 4 and 8%."9.05[The influence of metoprolol eye drops on intraocular pressure (author's transl)]. ( Aeschlimann, J; Bucheli, J; Gloor, B, 1980)
"Ten patients with ocular hypertension or glaucoma were treated over 4 months with the betablocker Metoprolol tartrate as 3% eye drops twice daily."9.05The long-term ocular and systemic effects of topically applied metoprolol tartrate in glaucoma and ocular hypertension. ( Krieglstein, GK, 1981)
"A double-masked cross-over comparison of the ocular hypotensive effect in 19 glaucoma patients between timolol 0."9.05Timolol and metoprolol in glaucoma. A comparison of the ocular hypotensive effect, local and systemic tolerance. ( Eriksen, JS; Nielsen, NV, 1981)
"The effect of a single dose metoprolol tablets or eye drops on intraocular pressure (IOP), blood pressure and heart rate was determined in healthy volunteers."9.05Effects of systemic and topical administration of metoprolol on intraocular pressure in healthy subjects. ( Alm, A; Wickström, CP, 1980)
"5% timolol eye drops on the intraocular pressure (IOP) was compared in healthy subjects."9.05Initial and long-term effects of metoprolol and timolol on the intraocular pressure. A comparison in healthy subjects. ( Alm, A; Törnquist, P; Wickström, CP, 1981)
"The effect on intraocular pressure (IOP) of topical timolol was studied in 30 patients with arterial hypertension treated with oral alprenolol, metoprolol or timolol."7.66Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade. ( Alvan, G; Calissendorff, BM; Haglund, K; Marén, N; Seideman, P, 1982)
"Oral doses of propranolol and metoprolol were tested on 24 patients without glaucoma."7.66[Effect of a single oral dose of propranolol or metoprolol on the intraocular pressure of persons without glaucoma (author's transl)]. ( Merkle, W; Merté, HJ, 1980)
"Eleven patients with previously untreated glaucoma of one eye were given metoprolol, 50 mg x 3 for one day."7.66The effect of metoprolol on intra-ocular pressure in glaucoma. A pilot study. ( Alm, A; Eckström, C; Ohman, L; Wickström, CP, 1979)
"The selective beta-1 blocker Metoprolol was tested for a period of one month in a double-blind trial involving 36 patients with open-angle glaucoma or intraocular hypertension in whom the substance was applied twice daily to the eye in concentrations of 1, 2, 4 and 8%."5.05[The influence of metoprolol eye drops on intraocular pressure (author's transl)]. ( Aeschlimann, J; Bucheli, J; Gloor, B, 1980)
"Ten patients with ocular hypertension or glaucoma were treated over 4 months with the betablocker Metoprolol tartrate as 3% eye drops twice daily."5.05The long-term ocular and systemic effects of topically applied metoprolol tartrate in glaucoma and ocular hypertension. ( Krieglstein, GK, 1981)
"A double-masked cross-over comparison of the ocular hypotensive effect in 19 glaucoma patients between timolol 0."5.05Timolol and metoprolol in glaucoma. A comparison of the ocular hypotensive effect, local and systemic tolerance. ( Eriksen, JS; Nielsen, NV, 1981)
"The beta1-selective beta-blocking agent Metoprolol gave a significant intraocular pressure decrease in different groups of open angle glaucoma patients in a concentration of 1% and 3%."5.04The effect of metoprolol on IOP (author's transl). ( Krieglstein, GK, 1978)
"The effect on intraocular pressure (IOP) of topical timolol was studied in 30 patients with arterial hypertension treated with oral alprenolol, metoprolol or timolol."3.66Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade. ( Alvan, G; Calissendorff, BM; Haglund, K; Marén, N; Seideman, P, 1982)
"A comparative study comprising 30 patients with glaucoma and 11 ocular hypertensives showed that pilocarpine 2%-4% and metoprolol 3% lowered the intraocular pressure to the same extent over a 4-week period."3.66Metoprolol eyedrops 3%, a short-term comparison with pilocarpine and a five-month follow-up study. (Multicenter). ( Ahrendt, N; Buhl, H; Byrn, E; Nielsen, PG, 1982)
"Generally, there are adequate to treat glaucoma without perimetric changes, while treatment of glaucoma with functional defects requires their association with miotics."1.26[Comparative clinical study of metoprolol and timolol (author's transl)]. ( Collignon-Brach, J; Weekers, R, 1981)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199021 (95.45)18.7374
1990's1 (4.55)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rowland, JM1
Potter, DE1
Green, K2
Elijah, D1
Lollis, G1
Mayberry, L1
Marén, N1
Alvan, G1
Calissendorff, BM1
Haglund, K1
Seideman, P1
Bucheli, J1
Aeschlimann, J1
Gloor, B1
Krieglstein, GK2
Nielsen, NV3
Eriksen, JS2
Nielsen, PG1
Ahrendt, N1
Buhl, H1
Byrn, E1
Alm, A3
Wickström, CP3
Collignon-Brach, J1
Weekers, R1
Törnquist, P1
Merté, HJ1
Merkle, W1
Bonomi, L1
Perfetti, S1
Noya, E1
Bellucci, R1
Massa, F1
Ros, FE1
Dake, CL1
Nagelkerke, NJ1
Greve, EL1
Eckström, C1
Ohman, L1
Shao, H1
Chiou, GC1
Watanabe, K1
McLaughlin, MA1
Liu, HK1
Palkama, A1
Uusitalo, H1
Raij, K1
Uusitalo, R1
Bodor, N1
el-Koussi, AA1
Kano, M1
Khalifa, MM1
Elijah, RD1
Hampstead, D1

Trials

9 trials available for metoprolol and Intraocular Pressure

ArticleYear
[The influence of metoprolol eye drops on intraocular pressure (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1980, Volume: 177, Issue:2

    Topics: Clinical Trials as Topic; Double-Blind Method; Glaucoma; Humans; Intraocular Pressure; Metoprolol; O

1980
The long-term ocular and systemic effects of topically applied metoprolol tartrate in glaucoma and ocular hypertension.
    Acta ophthalmologica, 1981, Volume: 59, Issue:1

    Topics: Blood Pressure; Clinical Trials as Topic; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Metopr

1981
Timolol and metoprolol. A diurnal study of the ocular and systemic effects in glaucoma patients.
    Acta ophthalmologica, 1981, Volume: 59, Issue:4

    Topics: Aged; Blood Pressure; Circadian Rhythm; Clinical Trials as Topic; Double-Blind Method; Female; Glauc

1981
Timolol and metoprolol in glaucoma. A comparison of the ocular hypotensive effect, local and systemic tolerance.
    Acta ophthalmologica, 1981, Volume: 59, Issue:3

    Topics: Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Heart Rate; H

1981
A diurnal study of the ocular hypotensive effect of metoprolol mounted on ophthalmic rods compared to timolol eye drops in glaucoma patients.
    Acta ophthalmologica, 1981, Volume: 59, Issue:4

    Topics: Aged; Blood Pressure; Circadian Rhythm; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocula

1981
Effects of systemic and topical administration of metoprolol on intraocular pressure in healthy subjects.
    Acta ophthalmologica, 1980, Volume: 58, Issue:5

    Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Dose-Response Relationship, Drug;

1980
Initial and long-term effects of metoprolol and timolol on the intraocular pressure. A comparison in healthy subjects.
    Acta ophthalmologica, 1981, Volume: 59, Issue:4

    Topics: Adult; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Metoprolol; Middle Aged; Pro

1981
Metoprolol eye drops in the treatment of glaucoma. A double-blind single-dose trial of a beta1-adrenergic blocking drug.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1978, Jun-19, Volume: 206, Issue:4

    Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug E

1978
The effect of metoprolol on IOP (author's transl).
    Klinische Monatsblatter fur Augenheilkunde, 1978, Volume: 173, Issue:5

    Topics: Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Gl

1978

Other Studies

13 other studies available for metoprolol and Intraocular Pressure

ArticleYear
Adrenergic drugs and intraocular pressure: suppression of ocular hypertension induced by water loading.
    Experimental eye research, 1980, Volume: 30, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Dobutamine; Ephedrine; Epinephrine; Intraocular Pr

1980
Beta adrenergic effects on ciliary epithelial permeability, aqueous humor formation and pseudofacility in the normal and sympathectomized rabbit eye.
    Current eye research, 1981, Volume: 1, Issue:7

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Butoxamine; Ciliary B

1981
Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade.
    Acta ophthalmologica, 1982, Volume: 60, Issue:1

    Topics: Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Alprenolol;

1982
Metoprolol eyedrops 3%, a short-term comparison with pilocarpine and a five-month follow-up study. (Multicenter).
    Acta ophthalmologica, 1982, Volume: 60, Issue:3

    Topics: Adult; Aged; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Me

1982
[Comparative clinical study of metoprolol and timolol (author's transl)].
    Journal francais d'ophtalmologie, 1981, Volume: 4, Issue:4

    Topics: Glaucoma; Humans; Intraocular Pressure; Metoprolol; Propanolamines; Time Factors; Timolol; Vasoconst

1981
[Effect of a single oral dose of propranolol or metoprolol on the intraocular pressure of persons without glaucoma (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1980, Volume: 176, Issue:1

    Topics: Administration, Oral; Glaucoma; Humans; Intraocular Pressure; Metoprolol; Propanolamines; Propranolo

1980
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1979, Mar-05, Volume: 210, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure;

1979
The effect of metoprolol on intra-ocular pressure in glaucoma. A pilot study.
    Acta ophthalmologica, 1979, Volume: 57, Issue:2

    Topics: Aged; Blood Pressure; Drug Evaluation; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; M

1979
[The effect of topical metoprolol on intraocular pressure].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 1991, Volume: 27, Issue:3

    Topics: Adult; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Metoprolol; Middle Aged; Op

1991
Are beta-adrenergic mechanisms involved in ocular hypotensive actions of adrenergic drugs?
    Ophthalmic research, 1985, Volume: 17, Issue:1

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Aqueous Humor; Butoxamine

1985
Comparison of the effects of adrenergic agonists and alpha-, beta 1-, beta 2-antagonists on the intraocular pressure and adenylate cyclase activity in the ciliary processes of the rabbit.
    Acta ophthalmologica, 1985, Volume: 63, Issue:1

    Topics: Acebutolol; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic b

1985
Soft drugs. 7. Soft beta-blockers for systemic and ophthalmic use.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:8

    Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Glaucoma; Heart Rate;

1988
Intraocular pressure and aqueous humor dynamics in rabbit and primate with d- and 1-adrenergic compounds.
    Journal of ocular pharmacology, 1986,Summer, Volume: 2, Issue:3

    Topics: Animals; Aqueous Humor; Butoxamine; Epinephrine; Intraocular Pressure; Macaca mulatta; Metoprolol; R

1986