metoprolol has been researched along with Insulin Resistance in 26 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We compared the effect of nebivolol (5 mg/d) and the β(1)-selective antagonist metoprolol (100 mg/d) on glucose homeostasis and markers of fibrinolysis in 46 subjects with metabolic syndrome." | 9.16 | Differential effects of nebivolol and metoprolol on insulin sensitivity and plasminogen activator inhibitor in the metabolic syndrome. ( Ayers, K; Brown, NJ; Byrne, LM; DeMatteo, A, 2012) |
| "Nebivolol, in contrast to metoprolol, improved oxidative stress, insulin sensitivity, decreased plasma soluble P-selectin and increased adiponectin levels in hypertensive patients." | 9.12 | Comparative effects of nebivolol and metoprolol on oxidative stress, insulin resistance, plasma adiponectin and soluble P-selectin levels in hypertensive patients. ( Celik, T; Fici, F; Isik, E; Iyisoy, A; Kardesoglu, E; Kilic, S; Kursaklioglu, H; Ozcan, O; Turhan, H; Yaman, H; Yilmaz, MI, 2006) |
| " Baseline to week 4 and 12, fasting blood glucose, serum lipid profile, BMI, C-peptide, insulin and homeostasis model assessment of insulin resistance (HOMA-IR) were measured." | 9.12 | After myocardial infarction carvedilol improves insulin resistance compared to metoprolol. ( Altuntas, Y; Basat, O; Oztekin, E; Seber, S; Ucak, S, 2006) |
| "We evaluated insulin sensitivity in two groups of essential hypertensive subjects before and after treatment with either long-acting nifedipine (nifedipine-CR, Adalat CR tablets; Bayer Yakuhin, Osaka, Japan) (n = 10) or metoprolol (n = 9)." | 9.10 | Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension. ( Harano, Y; Kodama, K; Koyama, Y; Suzuki, M, 2002) |
| " Carvedilol treatment, however, resulted in a small amelioration of insulin resistance and a better lipid profile [corrected]." | 9.08 | Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: the carvedilol-metoprolol study. ( Agrawal, B; Augustin, HJ; Dietze, GJ; Jacob, S; Rett, K; Wicklmayr, M, 1996) |
| " Therefore, we carried out a randomized, double-blind study to compare the effects of losartan (50 mg QD) and metoprolol (95 mg QD) on insulin sensitivity, insulin secretion, glucose tolerance, and lipids and lipoproteins in 20 hyperinsulinemic subjects with essential hypertension." | 9.08 | Effects of losartan on insulin sensitivity in hypertensive subjects. ( Karjalainen, L; Laakso, M; Lempiäinen-Kuosa, P, 1996) |
| "To evaluate the effect of metoprolol on insulin sensitivity and diurnal plasma hormone levels, seven mildly hypertensive subjects were investigated (four men and three women, age 52 +/- 8, body mass index 25." | 9.08 | The effect of metoprolol treatment on insulin sensitivity and diurnal plasma hormone levels in hypertensive subjects. ( Attvall, S; Bengtsson, BA; Elam, M; Fowelin, J; Gudbjörnsdóttir, S; Lönnroth, P; Mårin, P, 1997) |
| " Nondiabetics with hypertension (N=30) were started on (or changed to) hydrochlorothiazide (HCTZ) 12." | 7.73 | Metoprolol succinate, a selective beta-adrenergic blocker, has no effect on insulin sensitivity. ( Falkner, B; Francos, G; Kushner, H, 2006) |
| "Carvedilol effects were favorable to adjustment of age as a covariate." | 6.73 | Demographic analyses of the effects of carvedilol vs metoprolol on glycemic control and insulin sensitivity in patients with type 2 diabetes and hypertension in the Glycemic Effects in Diabetes Mellitus: Carvedilol-Metoprolol Comparison in Hypertensives ( ( Anderson, KM; Bakris, GL; Bell, DS; Fonseca, V; Iyengar, M; Katholi, RE; Lukas, MA; McGill, JB; Messerli, FH; Phillips, RA; Raskin, P; Wright, JT, 2008) |
| "ER metoprolol was then added to their ongoing therapy." | 5.35 | Treatment with metoprolol succinate, a selective beta adrenergic blocker, lowers blood pressure without altering insulin sensitivity in diabetic patients. ( Falkner, B; Kushner, H, 2008) |
| "Metoprolol was without significant effect on any of these variables following chronic administration." | 5.30 | The beta2-adrenergic modulator celiprolol reduces insulin resistance in obese Zucker rats. ( Dietze, GJ; Fogt, DL; Henriksen, EJ; Jacob, S, 1999) |
| " We compared the effect of nebivolol (5 mg/d) and the β(1)-selective antagonist metoprolol (100 mg/d) on glucose homeostasis and markers of fibrinolysis in 46 subjects with metabolic syndrome." | 5.16 | Differential effects of nebivolol and metoprolol on insulin sensitivity and plasminogen activator inhibitor in the metabolic syndrome. ( Ayers, K; Brown, NJ; Byrne, LM; DeMatteo, A, 2012) |
| "This study shows that vascular insulin sensitivity was preserved during treatment with carvedilol while blunted during treatment with metoprolol in patients with type 2 diabetes." | 5.14 | Metoprolol compared to carvedilol deteriorates insulin-stimulated endothelial function in patients with type 2 diabetes - a randomized study. ( Christiansen, B; Dominguez, H; Hermann, TS; Kveiborg, B; Køber, L; Major-Pedersen, A; Rask-Madsen, C; Raunsø, J; Torp-Pedersen, C, 2010) |
| "Nebivolol, in contrast to metoprolol, improved oxidative stress, insulin sensitivity, decreased plasma soluble P-selectin and increased adiponectin levels in hypertensive patients." | 5.12 | Comparative effects of nebivolol and metoprolol on oxidative stress, insulin resistance, plasma adiponectin and soluble P-selectin levels in hypertensive patients. ( Celik, T; Fici, F; Isik, E; Iyisoy, A; Kardesoglu, E; Kilic, S; Kursaklioglu, H; Ozcan, O; Turhan, H; Yaman, H; Yilmaz, MI, 2006) |
| " Baseline to week 4 and 12, fasting blood glucose, serum lipid profile, BMI, C-peptide, insulin and homeostasis model assessment of insulin resistance (HOMA-IR) were measured." | 5.12 | After myocardial infarction carvedilol improves insulin resistance compared to metoprolol. ( Altuntas, Y; Basat, O; Oztekin, E; Seber, S; Ucak, S, 2006) |
| "Changes in HbA1c and homeostasis model assessment-insulin resistance (HOMA-IR) were assessed over 5 months, comparing carvedilol with metoprolol tartrate according to insulin sensitizer (TZDs and metformin) use." | 5.12 | Differential effect of beta-blocker therapy on insulin resistance as a function of insulin sensitizer use: results from GEMINI. ( Anderson, KM; Bakris, GL; Bell, DS; Fonseca, V; Katholi, RE; Lukas, MA; McGill, JB; Messerli, FH; Phillips, RA; Raskin, P; Waterhouse, B; Wright, JT, 2007) |
| "We evaluated insulin sensitivity in two groups of essential hypertensive subjects before and after treatment with either long-acting nifedipine (nifedipine-CR, Adalat CR tablets; Bayer Yakuhin, Osaka, Japan) (n = 10) or metoprolol (n = 9)." | 5.10 | Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension. ( Harano, Y; Kodama, K; Koyama, Y; Suzuki, M, 2002) |
| " We compared the effects of captopril and metoprolol on the regression of LV mass and the relation to insulin sensitivity." | 5.09 | Regression of left ventricular mass with captopril and metoprolol, and the effects on glucose and lipid metabolism. ( Isaksson, H; Kahan, T; Malmqvist, K; Ostergren, J, 2001) |
| " Carvedilol treatment, however, resulted in a small amelioration of insulin resistance and a better lipid profile [corrected]." | 5.08 | Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: the carvedilol-metoprolol study. ( Agrawal, B; Augustin, HJ; Dietze, GJ; Jacob, S; Rett, K; Wicklmayr, M, 1996) |
| " Therefore, we carried out a randomized, double-blind study to compare the effects of losartan (50 mg QD) and metoprolol (95 mg QD) on insulin sensitivity, insulin secretion, glucose tolerance, and lipids and lipoproteins in 20 hyperinsulinemic subjects with essential hypertension." | 5.08 | Effects of losartan on insulin sensitivity in hypertensive subjects. ( Karjalainen, L; Laakso, M; Lempiäinen-Kuosa, P, 1996) |
| "To evaluate the effect of metoprolol on insulin sensitivity and diurnal plasma hormone levels, seven mildly hypertensive subjects were investigated (four men and three women, age 52 +/- 8, body mass index 25." | 5.08 | The effect of metoprolol treatment on insulin sensitivity and diurnal plasma hormone levels in hypertensive subjects. ( Attvall, S; Bengtsson, BA; Elam, M; Fowelin, J; Gudbjörnsdóttir, S; Lönnroth, P; Mårin, P, 1997) |
| "60 Patients with primary hypertension (diastolic blood pressure when resting supine 95-119 mm Hg on at least two occasions during four to six weeks of treatment with placebo) randomised to receive either metoprolol (n = 30) or atenolol (n = 30) during the first treatment period." | 5.06 | Sensitivity to insulin during treatment with atenolol and metoprolol: a randomised, double blind study of effects on carbohydrate and lipoprotein metabolism in hypertensive patients. ( Berne, C; Lithell, H; Pollare, T; Selinus, I, 1989) |
| " Nondiabetics with hypertension (N=30) were started on (or changed to) hydrochlorothiazide (HCTZ) 12." | 3.73 | Metoprolol succinate, a selective beta-adrenergic blocker, has no effect on insulin sensitivity. ( Falkner, B; Francos, G; Kushner, H, 2006) |
| "Carvedilol effects were favorable to adjustment of age as a covariate." | 2.73 | Demographic analyses of the effects of carvedilol vs metoprolol on glycemic control and insulin sensitivity in patients with type 2 diabetes and hypertension in the Glycemic Effects in Diabetes Mellitus: Carvedilol-Metoprolol Comparison in Hypertensives ( ( Anderson, KM; Bakris, GL; Bell, DS; Fonseca, V; Iyengar, M; Katholi, RE; Lukas, MA; McGill, JB; Messerli, FH; Phillips, RA; Raskin, P; Wright, JT, 2008) |
| "Insulin resistance was measured by homeostasis assessment index (HOMA)." | 2.73 | Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome. ( Acikel, C; Caglar, K; Celik, T; Eyileten, T; Oguz, Y; Sonmez, A; Vural, A; Yavuz, I; Yenicesu, M; Yilmaz, MI, 2007) |
| "Treatment with indapamide was followed by a significant decrease of plasma adiponectin concentration." | 2.73 | Indapamide decreases plasma adiponectin concentration in patients with essential hypertension. ( Adamczak, M; Chudek, J; Piecha, G; Wiecek, A, 2007) |
| "Insulin resistance is a condition in which cells are defective in response to the actions of insulin in tissue glucose uptake." | 1.43 | Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner. ( Denkaew, T; Mangmool, S; Nishida, M; Parichatikanond, W; Phosri, S; Pinthong, D; Shimauchi, T, 2016) |
| "Insulin resistance is prevalent in heart failure (HF) patients, and beta2 adrenergic receptors (beta2-AR) are involved in glucose homeostasis." | 1.35 | The beta2 adrenergic receptor Gln27Glu polymorphism affects insulin resistance in patients with heart failure: possible modulation by choice of beta blocker. ( Detry, MA; Johnson, MR; Moran, JJ; Sweitzer, NK; Vardeny, O, 2008) |
| "ER metoprolol was then added to their ongoing therapy." | 1.35 | Treatment with metoprolol succinate, a selective beta adrenergic blocker, lowers blood pressure without altering insulin sensitivity in diabetic patients. ( Falkner, B; Kushner, H, 2008) |
| "Metoprolol was without significant effect on any of these variables following chronic administration." | 1.30 | The beta2-adrenergic modulator celiprolol reduces insulin resistance in obese Zucker rats. ( Dietze, GJ; Fogt, DL; Henriksen, EJ; Jacob, S, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 15 (57.69) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Pearson, JT | 1 |
| Thambyah, HP | 1 |
| Waddingham, MT | 1 |
| Inagaki, T | 1 |
| Sukumaran, V | 1 |
| Ngo, JP | 1 |
| Ow, CPC | 1 |
| Sonobe, T | 1 |
| Chen, YC | 1 |
| Edgley, AJ | 1 |
| Fujii, Y | 1 |
| Du, CK | 1 |
| Zhan, DY | 1 |
| Umetani, K | 1 |
| Kelly, DJ | 1 |
| Tsuchimochi, H | 1 |
| Shirai, M | 1 |
| Mangmool, S | 1 |
| Denkaew, T | 1 |
| Phosri, S | 1 |
| Pinthong, D | 1 |
| Parichatikanond, W | 1 |
| Shimauchi, T | 1 |
| Nishida, M | 1 |
| Vardeny, O | 1 |
| Detry, MA | 1 |
| Moran, JJ | 1 |
| Johnson, MR | 1 |
| Sweitzer, NK | 1 |
| Phillips, RA | 2 |
| Fonseca, V | 2 |
| Katholi, RE | 2 |
| McGill, JB | 2 |
| Messerli, FH | 2 |
| Bell, DS | 2 |
| Raskin, P | 2 |
| Wright, JT | 2 |
| Iyengar, M | 1 |
| Anderson, KM | 2 |
| Lukas, MA | 2 |
| Bakris, GL | 2 |
| Kveiborg, B | 2 |
| Hermann, TS | 1 |
| Major-Pedersen, A | 1 |
| Christiansen, B | 2 |
| Rask-Madsen, C | 1 |
| Raunsø, J | 1 |
| Køber, L | 1 |
| Torp-Pedersen, C | 2 |
| Dominguez, H | 1 |
| Ayers, K | 1 |
| Byrne, LM | 1 |
| DeMatteo, A | 1 |
| Brown, NJ | 1 |
| Hamada, N | 1 |
| Nishi, Y | 1 |
| Tajiri, Y | 1 |
| Setoyama, K | 1 |
| Kamimura, R | 1 |
| Miyahara, K | 1 |
| Nuruki, N | 1 |
| Hosoda, H | 1 |
| Kangawa, K | 1 |
| Kojima, M | 1 |
| Mifune, H | 1 |
| Koyama, Y | 1 |
| Kodama, K | 1 |
| Suzuki, M | 1 |
| Harano, Y | 1 |
| Hara, Y | 1 |
| Hamada, M | 1 |
| Shigematsu, Y | 1 |
| Ohtsuka, T | 1 |
| Ogimoto, A | 1 |
| Higaki, J | 1 |
| Gonzalez-Feldman, E | 1 |
| Celik, T | 2 |
| Iyisoy, A | 1 |
| Kursaklioglu, H | 1 |
| Kardesoglu, E | 1 |
| Kilic, S | 1 |
| Turhan, H | 1 |
| Yilmaz, MI | 2 |
| Ozcan, O | 1 |
| Yaman, H | 1 |
| Isik, E | 1 |
| Fici, F | 1 |
| Basat, O | 1 |
| Ucak, S | 1 |
| Seber, S | 1 |
| Oztekin, E | 1 |
| Altuntas, Y | 1 |
| Falkner, B | 2 |
| Francos, G | 1 |
| Kushner, H | 2 |
| Major-Petersen, A | 1 |
| Sonmez, A | 1 |
| Caglar, K | 1 |
| Yenicesu, M | 1 |
| Eyileten, T | 1 |
| Acikel, C | 1 |
| Oguz, Y | 1 |
| Yavuz, I | 1 |
| Vural, A | 1 |
| Waterhouse, B | 1 |
| Piecha, G | 1 |
| Adamczak, M | 1 |
| Chudek, J | 1 |
| Wiecek, A | 1 |
| Mayer, MA | 1 |
| Höcht, C | 1 |
| Gironacci, M | 1 |
| Opezzo, JA | 1 |
| Taira, CA | 1 |
| Fernández, BE | 1 |
| Puyó, AM | 1 |
| Jacob, S | 2 |
| Rett, K | 1 |
| Wicklmayr, M | 1 |
| Agrawal, B | 1 |
| Augustin, HJ | 1 |
| Dietze, GJ | 2 |
| Laakso, M | 1 |
| Karjalainen, L | 1 |
| Lempiäinen-Kuosa, P | 1 |
| Gudbjörnsdóttir, S | 1 |
| Fowelin, J | 1 |
| Elam, M | 1 |
| Attvall, S | 1 |
| Bengtsson, BA | 1 |
| Mårin, P | 1 |
| Lönnroth, P | 1 |
| Fogt, DL | 1 |
| Henriksen, EJ | 1 |
| Malmqvist, K | 1 |
| Kahan, T | 1 |
| Isaksson, H | 1 |
| Ostergren, J | 1 |
| Lithell, HO | 1 |
| Pollare, T | 1 |
| Lithell, H | 1 |
| Selinus, I | 1 |
| Berne, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00497003] | Phase 4 | 50 participants (Actual) | Interventional | 2004-02-29 | Completed | ||
| Comparative Effect of Nebivolol vs. Metoprolol on Insulin Sensitivity and Fibrinolytic Balance in Metabolic Syndrome[NCT00775671] | Phase 4 | 46 participants (Actual) | Interventional | 2008-10-31 | Completed | ||
| Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Level in Hypertensive Patients: Speckle Tracking Echocardiography[NCT03990480] | Phase 4 | 230 participants (Actual) | Interventional | 2018-12-01 | Completed | ||
| The Effect of alpha1- Adrenergic Receptor Antagonist Therapy on Cardiac and Striatal Transporter Uptake in Pre-Motor and Symptomatic Parkinson's Disease: A Follow up Study[NCT05109364] | Phase 2 | 15 participants (Anticipated) | Interventional | 2022-09-23 | Recruiting | ||
| The Effect of Adrenergic Blocker Therapy on Cardiac and Striatal Transporter Uptake in Pre-Motor and Symptomatic Parkinson's Disease[NCT03775096] | Phase 2 | 15 participants (Anticipated) | Interventional | 2019-04-04 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Concentration of plasminogen activator inhibitor 1 (PAI-1)antigen. (NCT00775671)
Timeframe: After 12 weeks of study drug
| Intervention | ng/mL (Mean) |
|---|---|
| Nebivolol | 10.5 |
| Metoprolol | 12.3 |
The change in insulin sensitivity index, from baseline to after 12 weeks of treatment. Calculated from the intravenous glucose tolerance test at baseline and at 12 weeks. (NCT00775671)
Timeframe: 3 hours
| Intervention | 10-4xmin-1 per mU/L (Mean) |
|---|---|
| Nebivolol | 0.04 |
| Metoprolol | -1.5 |
2 reviews available for metoprolol and Insulin Resistance
| Article | Year |
|---|---|
Metabolic effects of beta-adrenoceptor antagonists with special emphasis on carvedilol.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Diabetes Mellitus; Glucose; Humans; In | 2006 |
Effect of antihypertensive drugs on insulin, glucose, and lipid metabolism.
Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Double-Blind Method; Glucose; Humans; | 1991 |
16 trials available for metoprolol and Insulin Resistance
| Article | Year |
|---|---|
Demographic analyses of the effects of carvedilol vs metoprolol on glycemic control and insulin sensitivity in patients with type 2 diabetes and hypertension in the Glycemic Effects in Diabetes Mellitus: Carvedilol-Metoprolol Comparison in Hypertensives (
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Blood Glucose; Blood Press | 2008 |
Metoprolol compared to carvedilol deteriorates insulin-stimulated endothelial function in patients with type 2 diabetes - a randomized study.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Denmark; Diabetes Mellitus, Type 2; Dose-Respon | 2010 |
Differential effects of nebivolol and metoprolol on insulin sensitivity and plasminogen activator inhibitor in the metabolic syndrome.
Topics: Adrenergic beta-Antagonists; Adult; Benzopyrans; Blood Glucose; Blood Pressure; Double-Blind Method; | 2012 |
Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Area Under Curve; Blood Glucose; Calcium Channel Blockers; Delaye | 2002 |
Effect of beta-blockers on insulin resistance in patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Echocardi | 2003 |
Comparative effects of nebivolol and metoprolol on oxidative stress, insulin resistance, plasma adiponectin and soluble P-selectin levels in hypertensive patients.
Topics: Adiponectin; Adult; Antihypertensive Agents; Benzopyrans; Ethanolamines; Female; Humans; Hypertensio | 2006 |
After myocardial infarction carvedilol improves insulin resistance compared to metoprolol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; C-Peptide; Carbazoles; Carve | 2006 |
Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome.
Topics: Adiponectin; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers | 2007 |
Differential effect of beta-blocker therapy on insulin resistance as a function of insulin sensitizer use: results from GEMINI.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Glucose; Carbazoles; Carvedilol; Diabete | 2007 |
Indapamide decreases plasma adiponectin concentration in patients with essential hypertension.
Topics: Adiponectin; Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Enalapril; Female; Glomerul | 2007 |
Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: the carvedilol-metoprolol study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Metho | 1996 |
Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: the carvedilol-metoprolol study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Metho | 1996 |
Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: the carvedilol-metoprolol study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Metho | 1996 |
Differential effect of chronic treatment with two beta-blocking agents on insulin sensitivity: the carvedilol-metoprolol study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Metho | 1996 |
Effects of losartan on insulin sensitivity in hypertensive subjects.
Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Double-Blind Method; Fatty Acids, Nones | 1996 |
The effect of metoprolol treatment on insulin sensitivity and diurnal plasma hormone levels in hypertensive subjects.
Topics: Adult; Blood Glucose; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Fem | 1997 |
Regression of left ventricular mass with captopril and metoprolol, and the effects on glucose and lipid metabolism.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood | 2001 |
Effect of antihypertensive drugs on insulin, glucose, and lipid metabolism.
Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Double-Blind Method; Glucose; Humans; | 1991 |
Sensitivity to insulin during treatment with atenolol and metoprolol: a randomised, double blind study of effects on carbohydrate and lipoprotein metabolism in hypertensive patients.
Topics: Atenolol; Blood Glucose; Cholesterol; Clinical Trials as Topic; Double-Blind Method; Female; Glucose | 1989 |
9 other studies available for metoprolol and Insulin Resistance
| Article | Year |
|---|---|
β-blockade prevents coronary macro- and microvascular dysfunction induced by a high salt diet and insulin resistance in the Goto-Kakizaki rat.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Carvedilol; Coronary A | 2021 |
Sustained βAR Stimulation Mediates Cardiac Insulin Resistance in a PKA-Dependent Manner.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclic AMP-Dependent Protein Kinases | 2016 |
The beta2 adrenergic receptor Gln27Glu polymorphism affects insulin resistance in patients with heart failure: possible modulation by choice of beta blocker.
Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; | 2008 |
Disrupted regulation of ghrelin production under antihypertensive treatment in spontaneously hypertensive rats.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Angiotensin II Type | 2012 |
Carvedilol, metoprolol, and insulin resistance.
Topics: Antihypertensive Agents; Carbazoles; Carvedilol; Diabetes Mellitus, Type 2; Humans; Hypertension; In | 2005 |
Metoprolol succinate, a selective beta-adrenergic blocker, has no effect on insulin sensitivity.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Cholesterol; Cholesterol, LDL; Female; Glucose | 2006 |
Hypothalamic angiotensinergic-noradrenergic systems interaction in fructose induced hypertension.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Fructose; Hypertension; Hypothalamus; Insulin | 2008 |
Treatment with metoprolol succinate, a selective beta adrenergic blocker, lowers blood pressure without altering insulin sensitivity in diabetic patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiop | 2008 |
The beta2-adrenergic modulator celiprolol reduces insulin resistance in obese Zucker rats.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Biological Transport, Active; Blood G | 1999 |