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metoprolol and Innate Inflammatory Response

metoprolol has been researched along with Innate Inflammatory Response in 15 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Research Excerpts

ExcerptRelevanceReference
"Carvedilol and N-acetyl cysteine (NAC) combination decreases inflammation, oxidative stress, and postoperative atrial fibrillation (POAF) rates more than metoprolol or carvedilol."9.19Oxidative status, inflammation, and postoperative atrial fibrillation with metoprolol vs carvedilol or carvedilol plus N-acetyl cysteine treatment. ( Akcay, S; Ceyhan, BM; Dogan, A; Erdogan, D; Icli, A; Okutan, H; Ozaydin, M; Peker, O; Sutcu, R; Uysal, BA; Varol, E; Yucel, H, 2014)
"Metoprolol exerts a disruptive action on neutrophil dynamics during exacerbated inflammation, resulting in an infarct-limiting effect not observed with atenolol or propranolol."7.96Metoprolol exerts a non-class effect against ischaemia-reperfusion injury by abrogating exacerbated inflammation. ( Clemente-Moragón, A; Fuster, V; García-Prieto, J; Gómez, M; Ibáñez, B; Lalama, DV; Martínez, F; Oliver, E; Sánchez-Cabo, F; Villena-Gutiérrez, R, 2020)
"This study evaluated the effects of early treatment with β-adrenergic blocker metoprolol on ventricular remodeling and function after acute myocardial infarction (AMI) by using high frequency ultrasound."7.78High-frequency ultrasound evaluation of effects of early treatment with metoprolol on myocardial inflammatory cytokine expression in rats with acute myocardial infarction. ( Gao, Y; Huang, L; Wu, W; Yang, Y; Zhang, J, 2012)
"Plasma concentrations after oral administration of the high extraction drug propranolol are increased in patients and animals with inflammation."7.67Effect of turpentine-induced inflammation on the disposition kinetics of propranolol, metoprolol, and antipyrine in the rat. ( Belpaire, FM; Bogaert, MG; Chindavijak, B; de Smet, F; Fraeyman, N, 1989)
"Metoprolol treatment attenuated vessel positive remodeling and reduced vulnerability index (1."5.35Effect of metoprolol on vulnerable plaque in rabbits by changing shear stress around plaque and reducing inflammation. ( Changjiang, L; Guihua, J; Huixia, L; Liang, C; Mei, Z; Runyi, S; Xiaobo, H; Xiaojun, C; Xiaonan, L; Xinsheng, X; Yanen, Z; Yun, Z, 2009)
"To investigate the changes of inflammatory cytokines in cardiac pacing patients with atrial fibrillation and asymptomatic atrial fibrillation and the effects of metoprolol on them."5.27Inflammatory cytokines in cardiac pacing patients with atrial fibrillation and asymptomatic atrial fibrillation. ( Kong, F; Lin, J; Pan, J; Wang, W; Wu, X; Zhang, M, 2018)
"Carvedilol and N-acetyl cysteine (NAC) combination decreases inflammation, oxidative stress, and postoperative atrial fibrillation (POAF) rates more than metoprolol or carvedilol."5.19Oxidative status, inflammation, and postoperative atrial fibrillation with metoprolol vs carvedilol or carvedilol plus N-acetyl cysteine treatment. ( Akcay, S; Ceyhan, BM; Dogan, A; Erdogan, D; Icli, A; Okutan, H; Ozaydin, M; Peker, O; Sutcu, R; Uysal, BA; Varol, E; Yucel, H, 2014)
"Metoprolol exerts a disruptive action on neutrophil dynamics during exacerbated inflammation, resulting in an infarct-limiting effect not observed with atenolol or propranolol."3.96Metoprolol exerts a non-class effect against ischaemia-reperfusion injury by abrogating exacerbated inflammation. ( Clemente-Moragón, A; Fuster, V; García-Prieto, J; Gómez, M; Ibáñez, B; Lalama, DV; Martínez, F; Oliver, E; Sánchez-Cabo, F; Villena-Gutiérrez, R, 2020)
"This study evaluated the effects of early treatment with β-adrenergic blocker metoprolol on ventricular remodeling and function after acute myocardial infarction (AMI) by using high frequency ultrasound."3.78High-frequency ultrasound evaluation of effects of early treatment with metoprolol on myocardial inflammatory cytokine expression in rats with acute myocardial infarction. ( Gao, Y; Huang, L; Wu, W; Yang, Y; Zhang, J, 2012)
"Plasma concentrations after oral administration of the high extraction drug propranolol are increased in patients and animals with inflammation."3.67Effect of turpentine-induced inflammation on the disposition kinetics of propranolol, metoprolol, and antipyrine in the rat. ( Belpaire, FM; Bogaert, MG; Chindavijak, B; de Smet, F; Fraeyman, N, 1989)
"Fibrinogen and WBC were independent predictors of CV death or non-fatal MI as well as disease progression leading to revascularization in patients with stable angina pectoris."2.69Inflammatory and hemostatic markers in relation to cardiovascular prognosis in patients with stable angina pectoris. Results from the APSIS study. The Angina Prognosis Study in Stockholm. ( Björkander, I; Forslund, L; Håkan Wallén, N; Held, C; Hjemdahl, P; Rehnqvist, N; Wiman, B, 2000)
"Other comorbidities included bronchial asthma, chronic sinusitis, ischemic heart disease, mild aortic stenosis, arterial hypertension, and degenerative thoracic spine disease."1.72Torasemide-induced Vascular Purpura in the Course of Eosinophilic Granulomatosis with Polyangiitis. ( Bergler-Czop, B; Frątczak, A; Miziołek, B; Polak, K, 2022)
"Metoprolol pretreatment reduced hepatic expression of proinflammatory cytokines and lowered plasma interleukin-6 (both p < ."1.36Cardioprotection, attenuated systemic inflammation, and survival benefit of beta1-adrenoceptor blockade in severe sepsis in rats. ( Ackland, GL; Dyson, A; Gourine, AV; Poputnikov, D; Rudiger, A; Singer, M; Stidwill, R; Yao, ST, 2010)
"Metoprolol treatment attenuated vessel positive remodeling and reduced vulnerability index (1."1.35Effect of metoprolol on vulnerable plaque in rabbits by changing shear stress around plaque and reducing inflammation. ( Changjiang, L; Guihua, J; Huixia, L; Liang, C; Mei, Z; Runyi, S; Xiaobo, H; Xiaojun, C; Xiaonan, L; Xinsheng, X; Yanen, Z; Yun, Z, 2009)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's0 (0.00)18.2507
2000's3 (20.00)29.6817
2010's6 (40.00)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Frątczak, A1
Polak, K1
Miziołek, B1
Bergler-Czop, B1
Clemente-Moragón, A1
Gómez, M1
Villena-Gutiérrez, R1
Lalama, DV1
García-Prieto, J1
Martínez, F1
Sánchez-Cabo, F1
Fuster, V1
Oliver, E1
Ibáñez, B1
Heusch, G1
Kleinbongard, P1
Zhang, K1
Tang, YD1
Zhang, Y1
Ojamaa, K1
Li, Y1
Saini, AS1
Carrillo-Sepulveda, MA1
Rajagopalan, V1
Gerdes, AM1
Pan, J2
Wang, W1
Wu, X1
Kong, F1
Lin, J1
Zhang, M1
Ozaydin, M1
Peker, O1
Erdogan, D1
Akcay, S1
Yucel, H1
Icli, A1
Ceyhan, BM1
Sutcu, R1
Uysal, BA1
Varol, E1
Dogan, A1
Okutan, H1
Liang, C1
Xiaonan, L1
Xiaojun, C1
Changjiang, L1
Xinsheng, X1
Guihua, J1
Xiaobo, H1
Yanen, Z1
Runyi, S1
Huixia, L1
Yun, Z1
Mei, Z1
Ackland, GL1
Yao, ST1
Rudiger, A1
Dyson, A1
Stidwill, R1
Poputnikov, D1
Singer, M1
Gourine, AV1
Sisakian, AS1
Davtian, AR1
Pepoian, SK1
Oganesian, AS1
Wu, W1
Huang, L1
Zhang, J1
Gao, Y1
Yang, Y1
Huang, CC1
Chen, PC1
Huang, CW1
Yu, J1
Schneider, RE1
Bishop, H1
Kendall, MJ1
Quarterman, CP1
Held, C1
Hjemdahl, P1
Håkan Wallén, N1
Björkander, I1
Forslund, L1
Wiman, B1
Rehnqvist, N1
Belpaire, FM2
de Smet, F1
Chindavijak, B1
Fraeyman, N1
Bogaert, MG2
Mugabo, P1
Rosseel, MT1

Trials

4 trials available for metoprolol and Innate Inflammatory Response

ArticleYear
Inflammatory cytokines in cardiac pacing patients with atrial fibrillation and asymptomatic atrial fibrillation.
    Panminerva medica, 2018, Volume: 60, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; C-Reactive Protein; Cytokines;

2018
Oxidative status, inflammation, and postoperative atrial fibrillation with metoprolol vs carvedilol or carvedilol plus N-acetyl cysteine treatment.
    Clinical cardiology, 2014, Volume: 37, Issue:5

    Topics: Acetylcysteine; Aged; Antihypertensive Agents; Atrial Fibrillation; Carbazoles; Cardiac Surgical Pro

2014
[The influence of beta-adrenoblocking therapy on the markers of systemic inflammation in patients with acute coronary syndrome].
    Klinicheskaia meditsina, 2011, Volume: 89, Issue:4

    Topics: Acute Coronary Syndrome; Adrenergic beta-1 Receptor Antagonists; Aged; Biomarkers; C-Reactive Protei

2011
Inflammatory and hemostatic markers in relation to cardiovascular prognosis in patients with stable angina pectoris. Results from the APSIS study. The Angina Prognosis Study in Stockholm.
    Atherosclerosis, 2000, Volume: 148, Issue:1

    Topics: Adrenergic beta-Agonists; Aged; Angina Pectoris; beta-Thromboglobulin; Calcium Channel Blockers; Car

2000

Other Studies

11 other studies available for metoprolol and Innate Inflammatory Response

ArticleYear
Torasemide-induced Vascular Purpura in the Course of Eosinophilic Granulomatosis with Polyangiitis.
    Acta dermatovenerologica Croatica : ADC, 2022, Volume: 30, Issue:2

    Topics: Adolescent; Aged; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Antihypertensive

2022
Metoprolol exerts a non-class effect against ischaemia-reperfusion injury by abrogating exacerbated inflammation.
    European heart journal, 2020, 12-07, Volume: 41, Issue:46

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Humans; Inflammation; Metoprolol; Mice; Myocardial I

2020
Is metoprolol more cardioprotective than other beta-blockers?
    European heart journal, 2020, 12-07, Volume: 41, Issue:46

    Topics: Adrenergic beta-Antagonists; Humans; Inflammation; Metoprolol; Reperfusion Injury

2020
Comparison of Therapeutic Triiodothyronine Versus Metoprolol in the Treatment of Myocardial Infarction in Rats.
    Thyroid : official journal of the American Thyroid Association, 2018, Volume: 28, Issue:6

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Echocardiography; Ele

2018
Effect of metoprolol on vulnerable plaque in rabbits by changing shear stress around plaque and reducing inflammation.
    European journal of pharmacology, 2009, Jun-24, Volume: 613, Issue:1-3

    Topics: Abdomen; Adrenergic beta-Antagonists; Animals; Aorta; Atherosclerosis; Cytokines; Gene Expression Re

2009
Cardioprotection, attenuated systemic inflammation, and survival benefit of beta1-adrenoceptor blockade in severe sepsis in rats.
    Critical care medicine, 2010, Volume: 38, Issue:2

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Atenolol; Cytokines; H

2010
High-frequency ultrasound evaluation of effects of early treatment with metoprolol on myocardial inflammatory cytokine expression in rats with acute myocardial infarction.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2012, Volume: 32, Issue:5

    Topics: Animals; Cytokines; Inflammation; Male; Metoprolol; Myocardial Infarction; Myocardium; Rats; Rats, S

2012
Aristolochic Acid induces heart failure in zebrafish embryos that is mediated by inflammation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 100, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aristolochic Acids; Cyclooxygenase 2; Cyclooxygen

2007
Effect of inflammatory disease on plasma concentrations of three beta-adrenoceptor blocking agents.
    International journal of clinical pharmacology, therapy, and toxicology, 1981, Volume: 19, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Proteins; Blood Sedimentation; Female; Humans; Infla

1981
Effect of turpentine-induced inflammation on the disposition kinetics of propranolol, metoprolol, and antipyrine in the rat.
    Fundamental & clinical pharmacology, 1989, Volume: 3, Issue:2

    Topics: Administration, Oral; Animals; Antipyrine; Inflammation; Injections, Intravenous; Male; Metoprolol;

1989
Binding to serum alpha 1-acid glycoprotein and effect of beta-adrenoceptor antagonists in rats with inflammation.
    British journal of pharmacology, 1986, Volume: 88, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Heart Rate; Inflammation; Injections, Intravenous; M

1986