Page last updated: 2024-10-31

metoprolol and Hypotension, Postural

metoprolol has been researched along with Hypotension, Postural in 13 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Research Excerpts

ExcerptRelevanceReference
"To investigate the influence of paroxetine on metoprolol concentrations and its effect in patients treated for acute myocardial infarction (AMI) who are routinely given paroxetine as a co-treatment of depression."9.13Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI). ( Babak, S; Bergman, U; Bertilsson, L; Boldueva, S; Burbello, A; Goryachkina, K, 2008)
"The orthostatic changes in heart rate (HR) and blood pressure (BP) were recorded in ten patients with stable angina pectoris before and after simultaneous sublingual nitroglycerin administration."9.05Orthostatic response before and after nitroglycerin in metoprolol- and verapamil-treated angina pectoris. ( Hyldstrup, L; Mogensen, NB; Nielsen, PE, 1983)
"The usefulness of esmolol in predicting the efficacy of treatment with an oral beta-adrenergic blocking agent was evaluated in 27 consecutive patients with neurocardiogenic syncope."7.68Use of intravenous esmolol to predict efficacy of oral beta-adrenergic blocker therapy in patients with neurocardiogenic syncope. ( Akhtar, M; Avitall, B; Jazayeri, MR; Murthy, VS; Shen, YH; Sra, JS; Troup, PJ, 1992)
"To investigate the influence of paroxetine on metoprolol concentrations and its effect in patients treated for acute myocardial infarction (AMI) who are routinely given paroxetine as a co-treatment of depression."5.13Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI). ( Babak, S; Bergman, U; Bertilsson, L; Boldueva, S; Burbello, A; Goryachkina, K, 2008)
"The orthostatic changes in heart rate (HR) and blood pressure (BP) were recorded in ten patients with stable angina pectoris before and after simultaneous sublingual nitroglycerin administration."5.05Orthostatic response before and after nitroglycerin in metoprolol- and verapamil-treated angina pectoris. ( Hyldstrup, L; Mogensen, NB; Nielsen, PE, 1983)
"The usefulness of esmolol in predicting the efficacy of treatment with an oral beta-adrenergic blocking agent was evaluated in 27 consecutive patients with neurocardiogenic syncope."3.68Use of intravenous esmolol to predict efficacy of oral beta-adrenergic blocker therapy in patients with neurocardiogenic syncope. ( Akhtar, M; Avitall, B; Jazayeri, MR; Murthy, VS; Shen, YH; Sra, JS; Troup, PJ, 1992)
"Although orthostatic hypotension (OH) is often considered a contraindication to blood pressure (BP) treatment, evidence is lacking."2.87Hypertension Treatment Effects on Orthostatic Hypotension and Its Relationship With Cardiovascular Disease. ( Appel, LJ; Juraschek, SP; Lipsitz, LA; Miller, ER; Mukamal, KJ, 2018)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19903 (23.08)18.7374
1990's5 (38.46)18.2507
2000's4 (30.77)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Juraschek, SP1
Appel, LJ1
Miller, ER1
Mukamal, KJ1
Lipsitz, LA1
Goryachkina, K1
Burbello, A1
Boldueva, S1
Babak, S1
Bergman, U1
Bertilsson, L1
Man in't Veld, AJ1
Boomsma, F1
Schalekamp, MA1
Hyldstrup, L1
Mogensen, NB1
Nielsen, PE1
Sneddon, JF1
Scalia, G1
Ward, DE1
McKenna, WJ1
Camm, AJ1
Frenneaux, MP1
Oldenburg, O1
Sack, S1
Erbel, R1
Philipp, T1
Kribben, A1
Shi, X1
Wray, DW1
Formes, KJ1
Wang, HW1
Hayes, PM1
O-Yurvati, AH1
Weiss, MS1
Reese, IP1
de Milliano, PA1
van Eck-Smit, BL1
de Groot, AC1
Lie, KI1
Allman, KC1
Williams, LC1
Turney, JH1
Parsons, V1
Sra, JS1
Murthy, VS1
Jazayeri, MR1
Shen, YH1
Troup, PJ1
Avitall, B1
Akhtar, M1
Dangovian, MI1
Jarandilla, R1
Frumin, H1
Kinney, RO1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of alpha1- Adrenergic Receptor Antagonist Therapy on Cardiac and Striatal Transporter Uptake in Pre-Motor and Symptomatic Parkinson's Disease: A Follow up Study[NCT05109364]Phase 215 participants (Anticipated)Interventional2022-09-23Recruiting
The Effect of Adrenergic Blocker Therapy on Cardiac and Striatal Transporter Uptake in Pre-Motor and Symptomatic Parkinson's Disease[NCT03775096]Phase 215 participants (Anticipated)Interventional2019-04-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for metoprolol and Hypotension, Postural

ArticleYear
[Therapy of orthostatic hypotension].
    Deutsche medizinische Wochenschrift (1946), 1999, Oct-15, Volume: 124, Issue:41

    Topics: Adrenergic beta-Antagonists; Cyclooxygenase Inhibitors; Deamino Arginine Vasopressin; Dihydroergotam

1999

Trials

3 trials available for metoprolol and Hypotension, Postural

ArticleYear
Hypertension Treatment Effects on Orthostatic Hypotension and Its Relationship With Cardiovascular Disease.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:4

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cardiovascular Di

2018
Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI).
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Area

2008
Orthostatic response before and after nitroglycerin in metoprolol- and verapamil-treated angina pectoris.
    Acta medica Scandinavica, 1983, Volume: 214, Issue:2

    Topics: Aged; Angina Pectoris; Blood Pressure; Heart Rate; Humans; Hypotension, Orthostatic; Metoprolol; Mid

1983

Other Studies

9 other studies available for metoprolol and Hypotension, Postural

ArticleYear
Effects of beta-adrenoceptor agonists and antagonists in patients with peripheral autonomic neuropathy.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:Suppl 2

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Albuterol; Amyloidosis; Autonomi

1982
Exercise induced vasodepressor syncope.
    British heart journal, 1994, Volume: 71, Issue:6

    Topics: Adolescent; Adult; Aged; Cardiac Output; Disopyramide; Exercise; Exercise Test; Female; Heart Rate;

1994
Orthostatic hypotension in aging humans.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Atropine; Blood Pressure; Female; Glycopyrrolate; H

2000
Metoprolol-induced changes in myocardial (123)I-metaiodobenzylguanidine uptake in Parkinson's disease.
    Circulation, 2000, Nov-14, Volume: 102, Issue:20

    Topics: 3-Iodobenzylguanidine; Anti-Arrhythmia Agents; Autonomic Nervous System Diseases; Heart; Humans; Hyp

2000
Metoprolol-induced changes in myocardial (123)I-metaiodobenzylguanidine uptake in Parkinson's disease.
    Circulation, 2000, Nov-14, Volume: 102, Issue:20

    Topics: 3-Iodobenzylguanidine; Anti-Arrhythmia Agents; Autonomic Nervous System Diseases; Heart; Humans; Hyp

2000
Metoprolol-induced changes in myocardial (123)I-metaiodobenzylguanidine uptake in Parkinson's disease.
    Circulation, 2000, Nov-14, Volume: 102, Issue:20

    Topics: 3-Iodobenzylguanidine; Anti-Arrhythmia Agents; Autonomic Nervous System Diseases; Heart; Humans; Hyp

2000
Metoprolol-induced changes in myocardial (123)I-metaiodobenzylguanidine uptake in Parkinson's disease.
    Circulation, 2000, Nov-14, Volume: 102, Issue:20

    Topics: 3-Iodobenzylguanidine; Anti-Arrhythmia Agents; Autonomic Nervous System Diseases; Heart; Humans; Hyp

2000
Metoprolol-induced changes in myocardial (123)I-metaiodobenzylguanidine uptake in Parkinson's disease.
    Circulation, 2001, Aug-14, Volume: 104, Issue:7

    Topics: 3-Iodobenzylguanidine; Heart; Humans; Hypotension, Orthostatic; Iodine Radioisotopes; Metoprolol; My

2001
Beta-blocker withdrawal syndrome.
    Lancet (London, England), 1979, Mar-03, Volume: 1, Issue:8114

    Topics: Aged; Female; Humans; Hypertension; Hypotension, Orthostatic; Metoprolol; Propanolamines; Substance

1979
Use of intravenous esmolol to predict efficacy of oral beta-adrenergic blocker therapy in patients with neurocardiogenic syncope.
    Journal of the American College of Cardiology, 1992, Volume: 19, Issue:2

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Female; Humans; Hypotension, Orthostatic; Isoprot

1992
Prolonged asystole during head-up tilt table testing after beta blockade.
    Pacing and clinical electrophysiology : PACE, 1992, Volume: 15, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Bradycardia; Female; Heart Arrest; Humans; Hypotension, Orthosta

1992
Cardiac arrest in an on-call intern.
    Hospital practice (Office ed.), 1991, Feb-15, Volume: 26, Issue:2

    Topics: Adult; Heart Arrest; Humans; Hypotension, Orthostatic; Male; Metoprolol; Syncope

1991