Page last updated: 2024-10-31

metoprolol and Hypertrophy

metoprolol has been researched along with Hypertrophy in 4 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Research Excerpts

ExcerptRelevanceReference
" Propranolol and metoprolol were given in the diet of spontaneously hypertensive (SH) rats during the development of hypertension."3.66Protein synthesis and composition of cardiac and vascular tissue in spontaneously hypertensive rats and the effects of beta-adrenergic antagonist treatment. ( Boström, SL; Fryklund, J, 1979)
" Metoprolol, a selective beta-1 receptor antagonist, significantly inhibited the glandular enlargement induced by dobutamine or isoproterenol and produced a parallel shift in the isoproterenol dose-response curve."1.26Adrenergic beta receptors mediating submandibular salivary gland hypertrophy in the rat. ( Brenner, GM; Wulf, RG, 1981)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahmet, I1
Lakatta, EG1
Talan, MI1
Brenner, GM1
Wulf, RG1
Mervaala, EM1
Teräväinen, TL1
Malmberg, L1
Laakso, J1
Pörsti, I1
Vapaatalo, H1
Karppanen, H1
Boström, SL1
Fryklund, J1

Other Studies

4 other studies available for metoprolol and Hypertrophy

ArticleYear
Pharmacological stimulation of beta2-adrenergic receptors (beta2AR) enhances therapeutic effectiveness of beta1AR blockade in rodent dilated ischemic cardiomyopathy.
    Heart failure reviews, 2005, Volume: 10, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta

2005
Adrenergic beta receptors mediating submandibular salivary gland hypertrophy in the rat.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Cardiomegaly; Dose-Response Relationship, Drug; Hypertrophy; Isop

1981
Cardiovascular and renal effects of the combination of felodipine and metoprolol during a high-salt and a moderate-salt diet in spontaneously hypertensive rats.
    Japanese circulation journal, 1997, Volume: 61, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combin

1997
Protein synthesis and composition of cardiac and vascular tissue in spontaneously hypertensive rats and the effects of beta-adrenergic antagonist treatment.
    Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5

    Topics: Animals; Heart; Hypertension; Hypertrophy; Male; Metoprolol; Muscle Proteins; Muscle, Smooth, Vascul

1979