Page last updated: 2024-10-31

metoprolol and Hypertrophy, Left Ventricular

metoprolol has been researched along with Hypertrophy, Left Ventricular in 38 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.

Research Excerpts

ExcerptRelevanceReference
"The Telmisartan Effectiveness on Left ventricular MAss Reduction (TELMAR) trial will assess the effect of the angiotensin II (Ang II) receptor blocker, telmisartan, on left ventricular hypertrophy (LVH) compared with the b-blocker, metoprolol, at similar antihypertensive doses."9.10Reduction (TELMAR) as assessed by magnetic resonance imaging in patients with mild-to-moderate hypertension--a prospective, randomised, double-blind comparison of telmisartan with metoprolol over a period of six months rationale and study design. ( Dahlöf, B; Dietz, R; Friedrich, MG; Knecht, M; Sechtem, U; Unger, T, 2003)
"The effects of perindopril and metoprolol on left ventricular hypertrophy (LVH) and function were studied in 47 essential hypertensive patients with LVH."9.08Effect of perindopril and metoprolol on left ventricular hypertrophy and performance in essential hypertension. ( Chen, X; Dai, Z; Hui, Y; Wang, W, 1995)
" In this study, we characterised left ventricular thrombospondin-1 and -4 expression in rats treated with a beta-blocker metoprolol during the remodelling process in response to pressure overload and acute myocardial infarction."7.76Metoprolol treatment lowers thrombospondin-4 expression in rats with myocardial infarction and left ventricular hypertrophy. ( Aro, J; Leskinen, H; Luodonpää, M; Mustonen, E; Ruskoaho, H; Rysä, J; Vuolteenaho, O, 2010)
"The Telmisartan Effectiveness on Left ventricular MAss Reduction (TELMAR) trial will assess the effect of the angiotensin II (Ang II) receptor blocker, telmisartan, on left ventricular hypertrophy (LVH) compared with the b-blocker, metoprolol, at similar antihypertensive doses."5.10Reduction (TELMAR) as assessed by magnetic resonance imaging in patients with mild-to-moderate hypertension--a prospective, randomised, double-blind comparison of telmisartan with metoprolol over a period of six months rationale and study design. ( Dahlöf, B; Dietz, R; Friedrich, MG; Knecht, M; Sechtem, U; Unger, T, 2003)
" We compared the effects of captopril and metoprolol on the regression of LV mass and the relation to insulin sensitivity."5.09Regression of left ventricular mass with captopril and metoprolol, and the effects on glucose and lipid metabolism. ( Isaksson, H; Kahan, T; Malmqvist, K; Ostergren, J, 2001)
" Twenty five unmedicated patients with primary hypertension were randomised to initial therapy with either the calcium antagonist, felodipine, or a diuretic and doses titrated to achieve similar levels of blood pressure (BP)."5.08Assessment of effects of two anti-hypertensive regimens on overall cardiovascular risk. ( Jennings, GL; Korner, P; Laufer, E; Reid, C; Sudhir, K, 1995)
"The effects of perindopril and metoprolol on left ventricular hypertrophy (LVH) and function were studied in 47 essential hypertensive patients with LVH."5.08Effect of perindopril and metoprolol on left ventricular hypertrophy and performance in essential hypertension. ( Chen, X; Dai, Z; Hui, Y; Wang, W, 1995)
" The curative effect of metoprolol tartrate and valsartan in reversing left ventricular hypertrophy in the group positive for autoantibodies was much better than in the negative group."3.80Autoantibodies against β1 receptor and AT1 receptor in type 2 diabetes patients with left ventricular dilatation. ( Xu, C; Xu, J; Zhao, L, 2014)
" In this study, we characterised left ventricular thrombospondin-1 and -4 expression in rats treated with a beta-blocker metoprolol during the remodelling process in response to pressure overload and acute myocardial infarction."3.76Metoprolol treatment lowers thrombospondin-4 expression in rats with myocardial infarction and left ventricular hypertrophy. ( Aro, J; Leskinen, H; Luodonpää, M; Mustonen, E; Ruskoaho, H; Rysä, J; Vuolteenaho, O, 2010)
" We aimed to verify whether the beta-blocker, metoprolol, and the pure heart-rate-reducing agent, ivabradine, have the same effects on haemodynamic function, ventricular remodeling, and Ca2+ handling in post-myocardial infarction (MI) heart failure in rat."3.74Effect of metoprolol and ivabradine on left ventricular remodelling and Ca2+ handling in the post-infarction rat heart. ( Mackiewicz, U; Maczewski, M, 2008)
"With carvedilol treatment, LVMI was lower (p<0."2.75Effect of carvedilol on coronary flow reserve in patients with hypertensive left-ventricular hypertrophy. ( Mei, Z; Xiaozhen, H; Yu, S; Yun, Z, 2010)
"Twenty-six men with dilated cardiomyopathy underwent serial echocardiography on days 0 and 1 and months 1 and 3 of either metoprolol (n = 16) or standard therapy (n = 10)."2.68Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade. ( Cigarroa, CG; Eichhorn, EJ; Grayburn, PA; Hall, SA; Marcoux, L; Risser, RC, 1995)
"Chronic left ventricular hypertrophy (LVH) is associated with depressed contractile performance, abnormal compliance of the chamber, and ultimately, the development of a left ventricular failure."2.68[The effect of hypotensive drugs on left ventricular mass and diastolic function]. ( Haczyński, J; Jołda-Mydłowska, B; Spring, A; Witkowska, M, 1995)
"The incidence of congestive heart failure is higher in diabetic patients, although the reasons for this increased rate are debated (higher incidence and severity of coronary heart disease and arterial hypertension, or a true diabetic cardiomyopathy)."2.41[Prevention and treatment of congestive heart failure in diabetic patients]. ( Anguita Sánchez, M, 2002)
"Treatment with ivabradine in patients within 2 years after HTX significantly reduced post-transplant heart rate and LV mass and was associated with a superior survival in comparison with patients receiving metoprolol succinate."1.48Control of cardiac chronotropic function in patients after heart transplantation: effects of ivabradine and metoprolol succinate on resting heart rate in the denervated heart. ( Bruckner, T; Darche, FF; Doesch, AO; Ehlermann, P; Helmschrott, M; Katus, HA; Rahm, AK; Rivinius, R; Ruhparwar, A; Thomas, D, 2018)
"Treatment with metoprolol effectively attenuated cardiac hypertrophy and reversed pressure overload induced changes on Dyrk1A and ASF, and alternative splicing of CaMKIIδ (all P < 0."1.39[Metoprolol attenuates pressure overload-induced myocardial hypertrophy through modulating Dryk1A-ASF-CaMKIIδ signaling pathways]. ( Gu, QQ; Lu, XC; Sheng, HZ; Yao, J; Zhu, JH, 2013)
"Hypertension is associated with left ventricular hypertrophy (LVH) and diastolic dysfunction."1.35Improvement of cardiac diastolic function by long-term centrally mediated sympathetic inhibition in one-kidney, one-clip hypertensive rabbits. ( Bousquet, PP; Monassier, LJ; Signolet, IL, 2008)
"3."1.29Improvement of cardiovascular effects of metoprolol by replacement of common salt with a potassium- and magnesium-enriched salt alternative. ( Karppanen, H; Laakso, J; Mervaala, EM; Vapaatalo, H, 1994)
"To discover whether in hypertensives with left ventricular hypertrophy (LVH) the increased muscle mass will completely regress under antihypertensive treatment and drug dosage can in consequence be reduced."1.29[Decreasing the antihypertensive dosage during longterm treatment and complete regression of left ventricular hypertrophy]. ( Behr, U; Franz, IW; Ketelhut, R; Tönnesmann, U, 1996)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's13 (34.21)18.2507
2000's14 (36.84)29.6817
2010's10 (26.32)24.3611
2020's1 (2.63)2.80

Authors

AuthorsStudies
Tang, J1
Wu, C1
Cao, J1
Wang, L2
Rivinius, R1
Helmschrott, M1
Ruhparwar, A1
Rahm, AK1
Darche, FF1
Thomas, D1
Bruckner, T1
Ehlermann, P1
Katus, HA1
Doesch, AO1
Davies, DR1
Bhatia, S1
Geske, JB1
Yao, J1
Sheng, HZ1
Lu, XC1
Gu, QQ1
Zhu, JH1
Nelipa, EA1
Salamatina, LV1
Urvantseva, IA1
Karnysheva, SI1
Raĭkovskaia, LR1
Rizzi, E1
Guimaraes, DA1
Ceron, CS1
Prado, CM1
Pinheiro, LC1
Martins-Oliveira, A1
Gerlach, RF1
Tanus-Santos, JE1
Zhao, L1
Xu, C1
Xu, J1
Ye, Y1
Gong, H1
Wang, X1
Wu, J1
Wang, S1
Yuan, J1
Yin, P1
Jiang, G1
Li, Y1
Ding, Z1
Zhang, W1
Zhou, J1
Ge, J1
Zou, Y1
Champetier, S2
Bojmehrani, A1
Beaudoin, J1
Lachance, D3
Plante, E3
Roussel, E3
Couet, J3
Arsenault, M3
Xiaozhen, H1
Yun, Z1
Mei, Z1
Yu, S1
Mustonen, E1
Leskinen, H1
Aro, J1
Luodonpää, M1
Vuolteenaho, O1
Ruskoaho, H1
Rysä, J1
Benedetto, U1
Melina, G1
Refice, S1
di Bartolomeo, R1
Roscitano, A1
Angeloni, E1
Sinatra, R1
Anguita Sánchez, M1
Friedrich, MG1
Dahlöf, B1
Sechtem, U1
Unger, T1
Knecht, M1
Dietz, R1
Gaudreau, M1
Drolet, MC2
Kobayashi, M1
Machida, N1
Mitsuishi, M1
Yamane, Y1
Binder, WD1
Fifer, MA1
King, ME1
Stone, JR1
Campos, LA1
Iliescu, R1
Fontes, MA1
Schlegel, WP1
Bader, M1
Baltatu, OC1
Perrino, C1
Naga Prasad, SV1
Mao, L1
Noma, T1
Yan, Z1
Kim, HS1
Smithies, O1
Rockman, HA1
Signolet, IL1
Bousquet, PP1
Monassier, LJ1
Maczewski, M1
Mackiewicz, U1
Sabri, A1
Rafiq, K1
Seqqat, R1
Kolpakov, MA1
Dillon, R1
Dell'italia, LJ1
Papademetriou, V1
Narayan, P1
Kokkinos, P1
Li, QP1
Rao, MR1
Jennings, GL1
Sudhir, K1
Laufer, E1
Korner, P1
Reid, C1
Vyssoulis, GP1
Kouremetis, MT1
Valiouli, MA1
Michaelides, AP1
Toutouzas, PK1
Hall, SA1
Cigarroa, CG1
Marcoux, L1
Risser, RC1
Grayburn, PA1
Eichhorn, EJ1
McDonald, KM1
Rector, T1
Carlyle, PF1
Francis, GS1
Cohn, JN1
Mervaala, EM2
Laakso, J2
Vapaatalo, H2
Karppanen, H2
Spring, A1
Haczyński, J1
Jołda-Mydłowska, B1
Witkowska, M1
Hui, Y1
Dai, Z1
Chen, X1
Wang, W1
Franz, IW1
Behr, U1
Ketelhut, R1
Tönnesmann, U1
Schobel, HP1
Langenfeld, M1
Gatzka, C1
Schmieder, RE1
Teräväinen, TL1
Malmberg, L1
Pörsti, I1
Yan, X1
Xiao, YB1
Grimm, D1
Huber, M1
Jabusch, HC1
Shakibaei, M1
Fredersdorf, S1
Paul, M1
Riegger, GA1
Kromer, EP1
Malmqvist, K1
Kahan, T1
Isaksson, H1
Ostergren, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Reverse Remodeling is Associated With Hemodynamic Improvement and Stabilization in Outpatients With Heart Failure With Reduced Ejection Fraction Treated With Sacubitril/Valsartan: an Echocardiographic Study[NCT04397302]652 participants (Actual)Observational [Patient Registry]2019-01-13Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for metoprolol and Hypertrophy, Left Ventricular

ArticleYear
[Prevention and treatment of congestive heart failure in diabetic patients].
    Revista espanola de cardiologia, 2002, Volume: 55, Issue:10

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Angiotensin

2002

Trials

12 trials available for metoprolol and Hypertrophy, Left Ventricular

ArticleYear
Effect of carvedilol on coronary flow reserve in patients with hypertensive left-ventricular hypertrophy.
    Blood pressure, 2010, Volume: 19, Issue:1

    Topics: Administration, Sublingual; Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Blood Pressure;

2010
Dual renin-angiotensin system blockade for patients with prosthesis-patient mismatch.
    The Annals of thoracic surgery, 2010, Volume: 90, Issue:6

    Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-C

2010
Reduction (TELMAR) as assessed by magnetic resonance imaging in patients with mild-to-moderate hypertension--a prospective, randomised, double-blind comparison of telmisartan with metoprolol over a period of six months rationale and study design.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2003, Volume: 4, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers

2003
Effects of diltiazem, metoprolol, enalapril and hydrochlorothiazide on frequency of ventricular premature complexes.
    The American journal of cardiology, 1994, Feb-01, Volume: 73, Issue:4

    Topics: Analysis of Variance; Antihypertensive Agents; Cardiac Complexes, Premature; Diltiazem; Echocardiogr

1994
Assessment of effects of two anti-hypertensive regimens on overall cardiovascular risk.
    Journal of human hypertension, 1995, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Pressure; Cardiovascular Diseases; Cholesterol; Diuretics; Drug Thera

1995
Effect of beta-blockade on exercise capacity in hypertensive subjects: a one-year double-blind study of celiprolol and metoprolol.
    Cardiovascular drugs and therapy, 1995, Volume: 9, Issue:1

    Topics: Adult; Aged; Blood Pressure; Body Mass Index; Celiprolol; Double-Blind Method; Echocardiography; Ele

1995
Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade.
    Journal of the American College of Cardiology, 1995, Volume: 25, Issue:5

    Topics: Analysis of Variance; Cardiomyopathy, Dilated; Cross-Over Studies; Double-Blind Method; Echocardiogr

1995
[The effect of hypotensive drugs on left ventricular mass and diastolic function].
    Polskie Archiwum Medycyny Wewnetrznej, 1995, Volume: 94, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Diastole; Drug Therapy, Combination;

1995
Effect of perindopril and metoprolol on left ventricular hypertrophy and performance in essential hypertension.
    Chinese medical journal, 1995, Volume: 108, Issue:9

    Topics: Adult; Antihypertensive Agents; Female; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventri

1995
Treatment and post-treatment effects of alpha- versus beta-receptor blockers on left ventricular structure and function in essential hypertension.
    American heart journal, 1996, Volume: 132, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Double-Blind Method; Female; Heart

1996
[Clinical study on effect of xinjikang capsule in reversing left ventricular hypertrophy].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1996, Volume: 16, Issue:9

    Topics: Animals; Antihypertensive Agents; Drugs, Chinese Herbal; Humans; Hypertrophy, Left Ventricular; Male

1996
Regression of left ventricular mass with captopril and metoprolol, and the effects on glucose and lipid metabolism.
    Blood pressure, 2001, Volume: 10, Issue:2

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood

2001

Other Studies

25 other studies available for metoprolol and Hypertrophy, Left Ventricular

ArticleYear
Fabry disease with early-onset ventricular dilation: A case report.
    Medicine, 2020, Sep-25, Volume: 99, Issue:39

    Topics: Adolescent; Aftercare; alpha-Galactosidase; Angiotensin-Converting Enzyme Inhibitors; Dilatation, Pa

2020
Control of cardiac chronotropic function in patients after heart transplantation: effects of ivabradine and metoprolol succinate on resting heart rate in the denervated heart.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2018, Volume: 107, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Benzazepines; Female; Germany; Heart; Heart Rate; Heart Transplantati

2018
58-Year-Old Asymptomatic Man With Left Ventricular Hypertrophy.
    Mayo Clinic proceedings, 2019, Volume: 94, Issue:7

    Topics: Adrenergic beta-1 Receptor Antagonists; Dyspnea; Echocardiography; Electrocardiography; Genetic Test

2019
[Metoprolol attenuates pressure overload-induced myocardial hypertrophy through modulating Dryk1A-ASF-CaMKIIδ signaling pathways].
    Zhonghua xin xue guan bing za zhi, 2013, Volume: 41, Issue:12

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dyrk Kinases; Hypertrophy, Left Ventric

2013
[A case of diagnosis of asymmetric apical hypertrophic cardiomyopathy of the left ventricle with intraventricular obstruction].
    Terapevticheskii arkhiv, 2014, Volume: 86, Issue:4

    Topics: Diagnosis, Differential; Echocardiography; Female; Heart Septal Defects, Ventricular; Humans; Hypert

2014
β1-Adrenergic blockers exert antioxidant effects, reduce matrix metalloproteinase activity, and improve renovascular hypertension-induced cardiac hypertrophy.
    Free radical biology & medicine, 2014, Volume: 73

    Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Antihypertensive Agents; Antioxidants; Benzopyrans;

2014
Autoantibodies against β1 receptor and AT1 receptor in type 2 diabetes patients with left ventricular dilatation.
    Cardiology, 2014, Volume: 129, Issue:3

    Topics: Aged; Antihypertensive Agents; Autoantibodies; Biomarkers; Diabetes Mellitus, Type 2; Dilatation, Pa

2014
Combination Treatment With Antihypertensive Agents Enhances the Effect of Qiliqiangxin on Chronic Pressure Overload-induced Cardiac Hypertrophy and Remodeling in Male Mice.
    Journal of cardiovascular pharmacology, 2015, Volume: 65, Issue:6

    Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme

2015
Gene profiling of left ventricle eccentric hypertrophy in aortic regurgitation in rats: rationale for targeting the beta-adrenergic and renin-angiotensin systems.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:3

    Topics: Acute Disease; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorti

2009
Metoprolol treatment lowers thrombospondin-4 expression in rats with myocardial infarction and left ventricular hypertrophy.
    Basic & clinical pharmacology & toxicology, 2010, Volume: 107, Issue:3

    Topics: Animals; Antihypertensive Agents; Hypertension; Hypertrophy, Left Ventricular; Male; Metoprolol; Myo

2010
Effectiveness of beta-blockade in experimental chronic aortic regurgitation.
    Circulation, 2004, Sep-14, Volume: 110, Issue:11

    Topics: Adrenergic beta-Antagonists; Animals; Aortic Valve Insufficiency; Catecholamines; Cell Size; Chronic

2004
Beta-blocker improves survival, left ventricular function, and myocardial remodeling in hypertensive rats with diastolic heart failure.
    American journal of hypertension, 2004, Volume: 17, Issue:12 Pt 1

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Disease Models, Animal; Echocardiography, Dopp

2004
Case records of the Massachusetts General Hospital. Case 26-2005. A 48-year-old man with sudden loss of consciousness while jogging.
    The New England journal of medicine, 2005, Aug-25, Volume: 353, Issue:8

    Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Death, Sudden, Cardiac; Diagnosis, Differentia

2005
Enhanced isoproterenol-induced cardiac hypertrophy in transgenic rats with low brain angiotensinogen.
    American journal of physiology. Heart and circulatory physiology, 2006, Volume: 291, Issue:5

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensinogen; Animals; Animals, Geneticall

2006
Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction.
    The Journal of clinical investigation, 2006, Volume: 116, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; beta-Adrenergic Receptor Kinases; Blood Pressure; Blood Vessel

2006
Improvement of cardiac diastolic function by long-term centrally mediated sympathetic inhibition in one-kidney, one-clip hypertensive rabbits.
    American journal of hypertension, 2008, Volume: 21, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiomyopathies; Dia

2008
Benefits of long-term beta-blockade in experimental chronic aortic regurgitation.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta

2008
Effect of metoprolol and ivabradine on left ventricular remodelling and Ca2+ handling in the post-infarction rat heart.
    Cardiovascular research, 2008, Jul-01, Volume: 79, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Benzazepines; Calcium; Disease Models, Animal; Heart Failure;

2008
Sympathetic activation causes focal adhesion signaling alteration in early compensated volume overload attributable to isolated mitral regurgitation in the dog.
    Circulation research, 2008, May-09, Volume: 102, Issue:9

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Apoptosis; Cells, Cult

2008
[Effects of calcium antagonists on withdrawal of beta-receptor blockers in rats during left ventricular hypertrophy].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:1

    Topics: Animals; Hemodynamics; Hypertrophy, Left Ventricular; Isomerism; Male; Metoprolol; Myocardium; Nifed

1995
Angiotensin-converting enzyme inhibition and beta-adrenoceptor blockade regress established ventricular remodeling in a canine model of discrete myocardial damage.
    Journal of the American College of Cardiology, 1994, Volume: 24, Issue:7

    Topics: Animals; Captopril; Dogs; Hemodynamics; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; M

1994
Improvement of cardiovascular effects of metoprolol by replacement of common salt with a potassium- and magnesium-enriched salt alternative.
    British journal of pharmacology, 1994, Volume: 112, Issue:2

    Topics: Animals; Blood Pressure; Cerebrovascular Disorders; Eating; Electrolytes; Heart Rate; Hemodynamics;

1994
[Decreasing the antihypertensive dosage during longterm treatment and complete regression of left ventricular hypertrophy].
    Deutsche medizinische Wochenschrift (1946), 1996, Apr-12, Volume: 121, Issue:15

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Echocardiography; Exercis

1996
Cardiovascular and renal effects of the combination of felodipine and metoprolol during a high-salt and a moderate-salt diet in spontaneously hypertensive rats.
    Japanese circulation journal, 1997, Volume: 61, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combin

1997
Extracellular matrix proteins in cardiac fibroblasts derived from rat hearts with chronic pressure overload: effects of beta-receptor blockade.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:3

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agent

2001