metoprolol has been researched along with Glaucoma in 11 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The selective beta-1 blocker Metoprolol was tested for a period of one month in a double-blind trial involving 36 patients with open-angle glaucoma or intraocular hypertension in whom the substance was applied twice daily to the eye in concentrations of 1, 2, 4 and 8%." | 9.05 | [The influence of metoprolol eye drops on intraocular pressure (author's transl)]. ( Aeschlimann, J; Bucheli, J; Gloor, B, 1980) |
| "Ten patients with ocular hypertension or glaucoma were treated over 4 months with the betablocker Metoprolol tartrate as 3% eye drops twice daily." | 9.05 | The long-term ocular and systemic effects of topically applied metoprolol tartrate in glaucoma and ocular hypertension. ( Krieglstein, GK, 1981) |
| "A double-masked cross-over comparison of the ocular hypotensive effect in 19 glaucoma patients between timolol 0." | 9.05 | Timolol and metoprolol in glaucoma. A comparison of the ocular hypotensive effect, local and systemic tolerance. ( Eriksen, JS; Nielsen, NV, 1981) |
| "Oral doses of propranolol and metoprolol were tested on 24 patients without glaucoma." | 7.66 | [Effect of a single oral dose of propranolol or metoprolol on the intraocular pressure of persons without glaucoma (author's transl)]. ( Merkle, W; Merté, HJ, 1980) |
| "Eleven patients with previously untreated glaucoma of one eye were given metoprolol, 50 mg x 3 for one day." | 7.66 | The effect of metoprolol on intra-ocular pressure in glaucoma. A pilot study. ( Alm, A; Eckström, C; Ohman, L; Wickström, CP, 1979) |
| "The selective beta-1 blocker Metoprolol was tested for a period of one month in a double-blind trial involving 36 patients with open-angle glaucoma or intraocular hypertension in whom the substance was applied twice daily to the eye in concentrations of 1, 2, 4 and 8%." | 5.05 | [The influence of metoprolol eye drops on intraocular pressure (author's transl)]. ( Aeschlimann, J; Bucheli, J; Gloor, B, 1980) |
| "Ten patients with ocular hypertension or glaucoma were treated over 4 months with the betablocker Metoprolol tartrate as 3% eye drops twice daily." | 5.05 | The long-term ocular and systemic effects of topically applied metoprolol tartrate in glaucoma and ocular hypertension. ( Krieglstein, GK, 1981) |
| "A double-masked cross-over comparison of the ocular hypotensive effect in 19 glaucoma patients between timolol 0." | 5.05 | Timolol and metoprolol in glaucoma. A comparison of the ocular hypotensive effect, local and systemic tolerance. ( Eriksen, JS; Nielsen, NV, 1981) |
| "The beta1-selective beta-blocking agent Metoprolol gave a significant intraocular pressure decrease in different groups of open angle glaucoma patients in a concentration of 1% and 3%." | 5.04 | The effect of metoprolol on IOP (author's transl). ( Krieglstein, GK, 1978) |
| "Generally, there are adequate to treat glaucoma without perimetric changes, while treatment of glaucoma with functional defects requires their association with miotics." | 1.26 | [Comparative clinical study of metoprolol and timolol (author's transl)]. ( Collignon-Brach, J; Weekers, R, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Urner-Bloch, U | 1 |
| Bucheli, J | 2 |
| Eltz, H | 1 |
| Gloor, B | 2 |
| Aeschlimann, J | 2 |
| Koch-Weser, J | 1 |
| Frishman, WH | 1 |
| Krieglstein, GK | 2 |
| Nielsen, NV | 1 |
| Eriksen, JS | 1 |
| Collignon-Brach, J | 1 |
| Weekers, R | 1 |
| Merté, HJ | 1 |
| Merkle, W | 1 |
| Ros, FE | 1 |
| Dake, CL | 1 |
| Nagelkerke, NJ | 1 |
| Greve, EL | 1 |
| Alm, A | 1 |
| Wickström, CP | 1 |
| Eckström, C | 1 |
| Ohman, L | 1 |
| Bodor, N | 1 |
| el-Koussi, AA | 1 |
| Kano, M | 1 |
| Khalifa, MM | 1 |
1 review available for metoprolol and Glaucoma
| Article | Year |
|---|---|
beta-Adrenoceptor antagonists: new drugs and new indications.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Glaucoma; Humans; Hypertension; Kinetics; Me | 1981 |
6 trials available for metoprolol and Glaucoma
| Article | Year |
|---|---|
[Clinical trials of various glaucoma drugs acting on the adrenergic system (author's transl)].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Drug Combinations; Epinephrine; Glaucoma; Gua | 1980 |
[The influence of metoprolol eye drops on intraocular pressure (author's transl)].
Topics: Clinical Trials as Topic; Double-Blind Method; Glaucoma; Humans; Intraocular Pressure; Metoprolol; O | 1980 |
The long-term ocular and systemic effects of topically applied metoprolol tartrate in glaucoma and ocular hypertension.
Topics: Blood Pressure; Clinical Trials as Topic; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Metopr | 1981 |
Timolol and metoprolol in glaucoma. A comparison of the ocular hypotensive effect, local and systemic tolerance.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Heart Rate; H | 1981 |
Metoprolol eye drops in the treatment of glaucoma. A double-blind single-dose trial of a beta1-adrenergic blocking drug.
Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Drug E | 1978 |
The effect of metoprolol on IOP (author's transl).
Topics: Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Gl | 1978 |
4 other studies available for metoprolol and Glaucoma
| Article | Year |
|---|---|
[Comparative clinical study of metoprolol and timolol (author's transl)].
Topics: Glaucoma; Humans; Intraocular Pressure; Metoprolol; Propanolamines; Time Factors; Timolol; Vasoconst | 1981 |
[Effect of a single oral dose of propranolol or metoprolol on the intraocular pressure of persons without glaucoma (author's transl)].
Topics: Administration, Oral; Glaucoma; Humans; Intraocular Pressure; Metoprolol; Propanolamines; Propranolo | 1980 |
The effect of metoprolol on intra-ocular pressure in glaucoma. A pilot study.
Topics: Aged; Blood Pressure; Drug Evaluation; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; M | 1979 |
Soft drugs. 7. Soft beta-blockers for systemic and ophthalmic use.
Topics: Animals; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Glaucoma; Heart Rate; | 1988 |