metoprolol has been researched along with Genetic Predisposition in 7 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 261 healthy individuals and 261 essential hypertension patients treated with metoprolol for 12 weeks were enrolled." | 3.88 | The Association of ADRB1 and CYP2D6 Polymorphisms With Antihypertensive Effects and Analysis of Their Contribution to Hypertension Risk. ( Chen, L; Deng, M; Wu, D; Xiao, T; Xie, S, 2018) |
| "Catecholaminergic polymorphic ventricular tachycardia was diagnosed with the aid of an implantable loop recorder." | 1.39 | A de novo novel cardiac ryanodine mutation (Ser4155Tyr) associated with catecholaminergic polymorphic ventricular tachycardia. ( Anastasakis, A; Kotsaka, X; Luria, D; Mantziari, L; Paraskevaidis, S; Styliadis, IH; Vassilikos, V, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jelinek, M | 1 |
| Wallach, C | 1 |
| Ehmke, H | 1 |
| Schwoerer, AP | 1 |
| Chen, L | 2 |
| Xiao, T | 1 |
| Xie, S | 1 |
| Deng, M | 1 |
| Wu, D | 1 |
| Mantziari, L | 1 |
| Vassilikos, V | 1 |
| Anastasakis, A | 1 |
| Kotsaka, X | 1 |
| Paraskevaidis, S | 1 |
| Styliadis, IH | 1 |
| Luria, D | 1 |
| Tagawa, M | 1 |
| Ochiai, S | 1 |
| Nakamura, Y | 1 |
| Sato, A | 1 |
| Chinushi, M | 1 |
| Jiang, Q | 1 |
| Yuan, H | 1 |
| Huang, Z | 1 |
| Hofman, N | 1 |
| Tan, HL | 1 |
| Alders, M | 1 |
| van Langen, IM | 1 |
| Wilde, AA | 1 |
| Newmark, JL | 1 |
| Voelkel, M | 1 |
| Brandom, BW | 1 |
| Wu, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Genetic Analysis of Heart Channelopathies in Brazilian Patients and Their Relatives[NCT04832126] | 100 participants (Anticipated) | Observational | 2018-01-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 other studies available for metoprolol and Genetic Predisposition
| Article | Year |
|---|---|
Genetic background dominates the susceptibility to ventricular arrhythmias in a murine model of β-adrenergic stimulation.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Arrhythmias, Cardiac; Gen | 2018 |
The Association of ADRB1 and CYP2D6 Polymorphisms With Antihypertensive Effects and Analysis of Their Contribution to Hypertension Risk.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Case-Control Studies; Cytochrome P-450 CYP2D6; Dyslip | 2018 |
A de novo novel cardiac ryanodine mutation (Ser4155Tyr) associated with catecholaminergic polymorphic ventricular tachycardia.
Topics: Adolescent; Anti-Arrhythmia Agents; Defibrillators, Implantable; Female; Flecainide; Follow-Up Studi | 2013 |
Secondly ECG recordings in the emergency room revealed Garenoxacin-induced abnormal QT interval prolongation in a patient with multiple syncopal attacks.
Topics: Adrenergic Agonists; Adrenergic beta-1 Receptor Antagonists; Aged; Anti-Bacterial Agents; Electrocar | 2016 |
DNA methylation might be the epigenetic molecular mechanism of different antihypertensive efficacy of metoprolol in beta1-AR gene-directed therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; DNA Methylation; Genetic Predisposition to Dis | 2009 |
Active cascade screening in primary inherited arrhythmia syndromes: does it lead to prophylactic treatment?
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cause of Death; Chi-Square Distribution; | 2010 |
Delayed onset of malignant hyperthermia without creatine kinase elevation in a geriatric, ryanodine receptor type 1 gene compound heterozygous patient.
Topics: Aged; Anesthesia, General; Anesthetics, Inhalation; Antihypertensive Agents; Blood Pressure; Colosto | 2007 |