metoprolol has been researched along with Drug-Related Side Effects and Adverse Reactions in 14 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Drug-Related Side Effects and Adverse Reactions: Disorders that result from the intended use of PHARMACEUTICAL PREPARATIONS. Included in this heading are a broad variety of chemically-induced adverse conditions due to toxicity, DRUG INTERACTIONS, and metabolic effects of pharmaceuticals.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Real-world spontaneous adverse event reports and administrative health care data were utilized as one part of a multipronged approach to verify surveillance signals related to generic drug formulations." | 1.51 | Real-World Data Approaches for Early Detection of Potential Safety and Effectiveness Signals for Generic Substitution: A Metoprolol Extended-Release Case Study. ( Brown, JD; Henriksen, C; Schmidt, S; Vozmediano, V, 2019) |
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| "5 million adverse drug reaction (ADR) reports for 8620 drugs/biologics that are listed for 1191 Coding Symbols for Thesaurus of Adverse Reaction (COSTAR) terms of adverse effects." | 1.32 | Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. ( Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matthews, EJ | 1 |
| Kruhlak, NL | 1 |
| Weaver, JL | 1 |
| Benz, RD | 1 |
| Contrera, JF | 1 |
| Pedersen, JM | 1 |
| Matsson, P | 1 |
| Bergström, CA | 1 |
| Norinder, U | 1 |
| Hoogstraate, J | 1 |
| Artursson, P | 1 |
| Chen, M | 1 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 2 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Ayyagari, R | 1 |
| Xie, J | 1 |
| Cheng, D | 1 |
| Wu, EQ | 1 |
| Huang, XY | 1 |
| Chen, S | 1 |
| Reap, LE | 1 |
| Rodd, C | 1 |
| Larios, J | 1 |
| Marshall, M | 1 |
| Brown, JD | 1 |
| Henriksen, C | 1 |
| Vozmediano, V | 1 |
| Schmidt, S | 1 |
| Donatelli, NS | 1 |
| Somes, J | 1 |
| Wagner, CC | 1 |
| Locher, P | 1 |
| Elke, B | 1 |
| Corti, N | 1 |
| Machado-Alba, JE | 1 |
| Giraldo-Giraldo, C | 1 |
| Moncada-Escobar, JC | 1 |
| Paxton, JW | 1 |
| Nederfors, T | 1 |
2 reviews available for metoprolol and Drug-Related Side Effects and Adverse Reactions
| Article | Year |
|---|---|
Beers list: what's NOT on "tap" for the older adult.
Topics: Aged, 80 and over; Antiemetics; Antihypertensive Agents; Arthritis; Chlorpropamide; Confusion; Diabe | 2013 |
[Frequent drug interactions in old age].
Topics: Adrenergic beta-Antagonists; Age Factors; Antihypertensive Agents; Cytochrome P-450 Enzyme System; D | 2009 |
12 other studies available for metoprolol and Drug-Related Side Effects and Adverse Reactions
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Dru | 2004 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Bi | 2008 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
A retrospective study evaluating the tolerability and effectiveness of adjunctive antihypertensive drugs in patients with inadequate response to initial treatment.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Drug-Related Side Effects and Adverse Reactions; F | 2018 |
Hydrochlorothizide-induced acute generalised exanthematous pustulosis presenting with bilateral periorbital impetigo.
Topics: Acute Generalized Exanthematous Pustulosis; Administration, Topical; Aged, 80 and over; Anti-Infecti | 2019 |
Real-World Data Approaches for Early Detection of Potential Safety and Effectiveness Signals for Generic Substitution: A Metoprolol Extended-Release Case Study.
Topics: Adverse Drug Reaction Reporting Systems; Databases, Factual; Drug Substitution; Drug-Related Side Ef | 2019 |
[Active pharmacosurveillance of patients affiliated to the Colombian general social security/health system].
Topics: Adverse Drug Reaction Reporting Systems; Calcium Channel Blockers; Clopidogrel; Colombia; Diphosphon | 2010 |
Pharmacogenetic polymorphism of drug metabolism.
Topics: Acetylation; Acetyltransferases; Debrisoquin; Drug Interactions; Drug-Related Side Effects and Adver | 1984 |
Protecting the poor metaboliser--from what?
Topics: Debrisoquin; Drug-Related Side Effects and Adverse Reactions; Humans; Hydroxylation; Metoprolol; Pha | 1984 |
Xerostomia: prevalence and pharmacotherapy. With special reference to beta-adrenoceptor antagonists.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Amylases; Antihypertensive | 1996 |