metoprolol has been researched along with Coronary Heart Disease in 195 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This meta-analysis aimed to systematically and comprehensively assess the effectiveness and safety of wenxin granule (WXG) and metoprolol in the treatment of elderly patients with coronary heart disease (CHD) and arrhythmia." | 9.22 | A meta-analysis of wenxin granule and metoprolol for the treatment of coronary heart disease and arrhythmia. ( Huang, W; Meng, LL, 2022) |
| "To evaluate the effects of Verapamil and Metoprolol on improving heart rate variability(HRV) in patients with coronary heart disease (CHD)." | 9.12 | [Effects of Verapamil and Metoprolol on heart rate variability in patients with coronary heart disease]. ( Lu, XN; Sun, NL; Zhang, Q, 2007) |
| "This clinical trial was performed to determine the safety and clinical impact of titrated metoprolol therapy in patients with heart failure, documented coronary artery disease and a low ejection fraction." | 9.07 | Beneficial effects of metoprolol in heart failure associated with coronary artery disease: a randomized trial. ( Bennett, SK; Fisher, ML; Gottlieb, SS; Greenberg, NL; Hamilton, BP; Patten, RD; Plotnick, GD, 1994) |
| "The effects of the beta-adrenoceptor-blocking drugs propranolol, metoprolol, pindolol, and placebo, on mucociliary clearance were studied in three groups of 6 subjects with coronary heart disease and normal lung function." | 9.05 | Influence of propranolol, metoprolol, and pindolol on mucociliary clearance in patients with coronary heart disease. ( Dorow, P; Felix, R; Schiess, W; Schmutzler, H; Weiss, T, 1984) |
| "Conventional formulations of metoprolol have become well established in cardiovascular medicine and are particularly useful in the management of hypertension and ischaemic heart disease." | 8.78 | Controlled release metoprolol formulations. A review of their pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and ischaemic heart disease. ( Clissold, SP; Plosker, GL, 1992) |
| "During the intervening years since metoprolol was first reviewed in the Journal (1977), it has become widely used in the treatment of mild to moderate hypertension and angina pectoris." | 8.77 | Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders. ( Benfield, P; Brogden, RN; Clissold, SP, 1986) |
| " In order to explore the demand for cardiovascular disease treatment, make up for the lack of chronic diseases affecting people's physical harm, and improve the success rate of cardiovascular disease treatment, a method to observe the efficacy and myocardial remodeling of trimetazidine combined with metoprolol in elderly patients with coronary heart disease and heart failure based on integrated traditional Chinese and Western medicine was proposed." | 8.12 | Observation of Curative Effect of Trimetazidine Combined with Metoprolol in Elderly Patients with Coronary Heart Disease Complicated with Heart Failure and the Effect of Myocardial Remodeling by Integrated Traditional Chinese and Western Medicine. ( Lu, Y; Ni, H; Shi, H; Sun, Y; Wang, F, 2022) |
| "Although carvedilol attenuates left ventricular (LV) remodeling in coronary occlusion-reperfusion, it is not known whether it attenuates ischemic LV remodeling because of coronary stenosis (CS) or permanent coronary occlusion (CO)." | 7.71 | Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats. ( Maehara, K; Maruyama, Y; Sakabe, A; Yaoita, H, 2002) |
| "To define the effects of 2 months of metoprolol therapy on cardiac function, aerobic performance and sympathetic nervous system activity, metoprolol (75 to 100 mg/day) was administered to 10 patients with chronic congestive heart failure (CHF)." | 7.68 | Effects of metoprolol on rest and exercise cardiac function and plasma catecholamines in chronic congestive heart failure secondary to ischemic or idiopathic cardiomyopathy. ( Abrass, IB; Nemanich, JW; Stratton, JR; Veith, RC, 1990) |
| "The effects of chlorthalidone and metoprolol on fasting plasma lipids and lipoprotein levels were compared in two similar nonrandomized groups of patients with mild hypertension." | 7.67 | Different effects of metoprolol and chlorthalidone on serum lipoprotein levels in mild hypertension. Possible implications for coronary heart disease risk status. ( Goldbourt, U; Holtzman, E; Rosenthal, T; Segal, P, 1984) |
| "By unidirectionally affecting the vasomotor function of the endothelium, ivabradine in combination with perindopril versus metoprolol has a more favorable effect on circulatory resistance and blood flow velocity in the brachiocephalic arteries of patients with CHD and AH." | 6.77 | [Cerebral blood flow and endothelial functional activity in patients with coronary heart disease and arterial hypertension during therapy with ivabradine in combination with perindopril]. ( Gapon, LI; Kolesnikova, SN; Musikhina, NA; Petelina, TI; Utesheva, AB, 2012) |
| "Nifedipine was ineffective, particularly in patients with angina predominantly on effort and with a moderate to severe reduction in exercise tolerance." | 6.67 | Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine. ( Ardissino, D; Egstrup, K; Feruglio, GA; Giordano, MP; Marraccini, P; Roncarolo, P; Rosenfeld, M; Savonitto, S; Slavich, G; Wahlqvist, I, 1991) |
| "Celiprolol is a 'third generation' beta-blocking agent which is claimed to avoid problems associated with simpler beta-blockers, such as vasoconstriction, bronchoconstriction and myocardial depression." | 6.67 | Acute haemodynamic profile of celiprolol in patients with coronary heart disease and hypertension: a double-blind comparison with metoprolol. ( Franz, N; Heublein, B; Modersohn, D; Panzner, B, 1991) |
| "Diltiazem was found to be effective in 74% of the patients with exertional angina, whereas metoprolol was beneficial in 62%." | 6.67 | [Comparison of antianginal effects of diltiazem and metoprolol in patients with ischemic heart disease with different clinical forms of angina pectoris]. ( Guliev, AB; Iaroshevskaia, FM; Krutovskikh, IV; Lupanov, VP; Sidorenko, BA, 1990) |
| "A distinct phase of ventricular arrhythmias was evident about 10 to 30 min after ligation." | 5.27 | Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP. ( Gihwala, D; Hamm, CW; Muller, CA; Opie, LH; Peisach, M, 1986) |
| " There were statistically significant dose-response reductions in systolic and diastolic pressures, heart rate and cardiac output together with a dose-related increase in pulmonary wedge pressure." | 5.26 | Haemodynamic dose-response effects of i.v. metoprolol in coronary heart disease. ( Hendry, WG; Silke, B; Taylor, SH, 1981) |
| "This meta-analysis aimed to systematically and comprehensively assess the effectiveness and safety of wenxin granule (WXG) and metoprolol in the treatment of elderly patients with coronary heart disease (CHD) and arrhythmia." | 5.22 | A meta-analysis of wenxin granule and metoprolol for the treatment of coronary heart disease and arrhythmia. ( Huang, W; Meng, LL, 2022) |
| "To evaluate the effects of Verapamil and Metoprolol on improving heart rate variability(HRV) in patients with coronary heart disease (CHD)." | 5.12 | [Effects of Verapamil and Metoprolol on heart rate variability in patients with coronary heart disease]. ( Lu, XN; Sun, NL; Zhang, Q, 2007) |
| "In a prospective trial assessing the effects of beta-blockers on sexual function men with coronary heart disease were randomized to a 4 month treatment with sustained release metoprolol 95 mg or placebo." | 5.09 | Effects of beta-blockers on sexual performance in men with coronary heart disease. A prospective, randomized and double blinded study. ( Braun, M; Franzen, D; Höpp, HW; Metha, A; Seifert, N, 2001) |
| " In the hypertensive patients with coronary disease the authors also evaluated sympathetic activation after double-blind, placebo-controlled administration of metoprolol (100 mg/day), followed by amlodipine (10 mg/day), quinapril (20 mg/day), and amlodipine (5 mg/day) plus quinapril (10 mg/day)." | 5.08 | Power spectral analysis of heart rate in elderly hypertensive subjects with or without silent coronary disease. ( Bucca, C; Cacciafesta, M; Di Gioacchino, C; Durante, M; Fimognari, FL; Lo Verde, A; Marigliano, V; Monteforte, G; Munizzi, MR; Piccirillo, G; Santagada, E; Tarantini, S; Viola, E, 1996) |
| "This clinical trial was performed to determine the safety and clinical impact of titrated metoprolol therapy in patients with heart failure, documented coronary artery disease and a low ejection fraction." | 5.07 | Beneficial effects of metoprolol in heart failure associated with coronary artery disease: a randomized trial. ( Bennett, SK; Fisher, ML; Gottlieb, SS; Greenberg, NL; Hamilton, BP; Patten, RD; Plotnick, GD, 1994) |
| "The use of metoprolol combined with nifedipine and diltiazem was studied and compared in 32 patients suffering from coronary disease associated with angina pectoris of effort." | 5.06 | [The use of metoprolol with calcium antagonists of different mechanisms of action (diltiazem and nifedipine) in patients with stenocardia of effort]. ( Guliev, AB; Lupanov, VP; Sidorenko, BA, 1990) |
| "The question whether initial antihypertensive treatment with a beta-blocker prevents hypertensive complications better than initial treatment with a non-betablocker, mainly diuretic based treatment, has been studied in recent large-scale studies like the Medical Research Council (MRC) trial, the International Prospective Primary Prevention Study in Hypertension (IPPPSH), the Heart Attack Primary Prevention in Hypertension (HAPPHY) study and the Metoprolol Atherosclerosis Prevention in Hypertensives (MAPHY) study." | 5.06 | Beta-blockers and diuretics. The HAPPHY and MAPHY studies. ( Berglund, G, 1989) |
| "The effects of the beta-adrenoceptor-blocking drugs propranolol, metoprolol, pindolol, and placebo, on mucociliary clearance were studied in three groups of 6 subjects with coronary heart disease and normal lung function." | 5.05 | Influence of propranolol, metoprolol, and pindolol on mucociliary clearance in patients with coronary heart disease. ( Dorow, P; Felix, R; Schiess, W; Schmutzler, H; Weiss, T, 1984) |
| "Conventional formulations of metoprolol have become well established in cardiovascular medicine and are particularly useful in the management of hypertension and ischaemic heart disease." | 4.78 | Controlled release metoprolol formulations. A review of their pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and ischaemic heart disease. ( Clissold, SP; Plosker, GL, 1992) |
| "During the intervening years since metoprolol was first reviewed in the Journal (1977), it has become widely used in the treatment of mild to moderate hypertension and angina pectoris." | 4.77 | Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders. ( Benfield, P; Brogden, RN; Clissold, SP, 1986) |
| " In order to explore the demand for cardiovascular disease treatment, make up for the lack of chronic diseases affecting people's physical harm, and improve the success rate of cardiovascular disease treatment, a method to observe the efficacy and myocardial remodeling of trimetazidine combined with metoprolol in elderly patients with coronary heart disease and heart failure based on integrated traditional Chinese and Western medicine was proposed." | 4.12 | Observation of Curative Effect of Trimetazidine Combined with Metoprolol in Elderly Patients with Coronary Heart Disease Complicated with Heart Failure and the Effect of Myocardial Remodeling by Integrated Traditional Chinese and Western Medicine. ( Lu, Y; Ni, H; Shi, H; Sun, Y; Wang, F, 2022) |
| "The aim of this study was to investigate the effect of a beta-blocker (atenolol and metoprolol) on exercise heart rate (HR) and rate pressure product (RPP) during a morning and afternoon maximal exercise test (maxET) in patients with coronary heart disease (CHD)." | 3.74 | Time-of-day variation in cardiovascular response to maximal exercise testing in coronary heart disease patients taking a beta-blocker. ( Boulay, P; Dufour Doiron, M; Prud'homme, D, 2007) |
| "Although carvedilol attenuates left ventricular (LV) remodeling in coronary occlusion-reperfusion, it is not known whether it attenuates ischemic LV remodeling because of coronary stenosis (CS) or permanent coronary occlusion (CO)." | 3.71 | Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats. ( Maehara, K; Maruyama, Y; Sakabe, A; Yaoita, H, 2002) |
| "To evaluate the effect of combined use of Chinese herbal medicine, Captopril and Metoprolol in treating mild-middle degree congestive heart failure." | 3.70 | [Clinical study on treatment of mild-middle degree congestive heart failure with integrated traditional Chinese and Western medicine]. ( He, H; Xu, Y; Zhao, W, 2000) |
| "Metoprolol was examined for its effects on clinical manifestations of the disease, peripheral hemodynamic and myocardial contractile parameters in 46 patients with coronary heart disease." | 3.68 | [Effect of 4-week metoprolol treatment on clinical manifestations and cardiac hemodynamics in patients with ischemic heart disease]. ( Vartanova, OA, 1990) |
| "To define the effects of 2 months of metoprolol therapy on cardiac function, aerobic performance and sympathetic nervous system activity, metoprolol (75 to 100 mg/day) was administered to 10 patients with chronic congestive heart failure (CHF)." | 3.68 | Effects of metoprolol on rest and exercise cardiac function and plasma catecholamines in chronic congestive heart failure secondary to ischemic or idiopathic cardiomyopathy. ( Abrass, IB; Nemanich, JW; Stratton, JR; Veith, RC, 1990) |
| "The effects of chlorthalidone and metoprolol on fasting plasma lipids and lipoprotein levels were compared in two similar nonrandomized groups of patients with mild hypertension." | 3.67 | Different effects of metoprolol and chlorthalidone on serum lipoprotein levels in mild hypertension. Possible implications for coronary heart disease risk status. ( Goldbourt, U; Holtzman, E; Rosenthal, T; Segal, P, 1984) |
| " We administered 40-, 80- and 120-mg doses of verapamil orally to 15 patients with angina pectoris who were receiving high doses of propranolol or metoprolol." | 3.66 | Hemodynamic consequences of combined beta-adrenergic and slow calcium channel blockade in man. ( Gorlin, R; Guererro, J; Holt, J; McAllister, RG; Medina, N; Meller, J; Packer, M; Smith, H; Todd, GD; Yushak, M, 1982) |
| "Three patients with ischaemic heart disease developed profound cardiac failure, hypotension and bradycardia during combined therapy with verapamil and beta-adrenergic blocking drugs." | 3.66 | Adverse interaction between beta-adrenergic blocking drugs and verapamil--report of three cases. ( Anderson, ST; Federman, J; Harper, RW; Laufer, E; Pitt, A; Wayne, VS, 1982) |
| "By unidirectionally affecting the vasomotor function of the endothelium, ivabradine in combination with perindopril versus metoprolol has a more favorable effect on circulatory resistance and blood flow velocity in the brachiocephalic arteries of patients with CHD and AH." | 2.77 | [Cerebral blood flow and endothelial functional activity in patients with coronary heart disease and arterial hypertension during therapy with ivabradine in combination with perindopril]. ( Gapon, LI; Kolesnikova, SN; Musikhina, NA; Petelina, TI; Utesheva, AB, 2012) |
| "In patients prone to sudden cardiac death, there is a reduction in TWA amplitude following the administration of antiadrenergic drugs." | 2.70 | Effect of metoprolol and d,l-sotalol on microvolt-level T-wave alternans. Results of a prospective, double-blind, randomized study. ( Grönefeld, G; Hohnloser, SH; Klingenheben, T; Li, YG, 2001) |
| "Metoprolol tended to lower chest pain and reduce precordial ST-segment elevation due to angioplasty, but the effects were not statistically significant." | 2.67 | Absence of beneficial effect of intravenous metoprolol given during angioplasty in patients with single-vessel coronary artery disease. ( Bonnier, JJ; Ciampricotti, R; de Jong, JW; Huizer, T; Roelandt, JR, 1993) |
| "Celiprolol is a 'third generation' beta-blocking agent which is claimed to avoid problems associated with simpler beta-blockers, such as vasoconstriction, bronchoconstriction and myocardial depression." | 2.67 | Acute haemodynamic profile of celiprolol in patients with coronary heart disease and hypertension: a double-blind comparison with metoprolol. ( Franz, N; Heublein, B; Modersohn, D; Panzner, B, 1991) |
| "Nifedipine was ineffective, particularly in patients with angina predominantly on effort and with a moderate to severe reduction in exercise tolerance." | 2.67 | Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine. ( Ardissino, D; Egstrup, K; Feruglio, GA; Giordano, MP; Marraccini, P; Roncarolo, P; Rosenfeld, M; Savonitto, S; Slavich, G; Wahlqvist, I, 1991) |
| "Diltiazem was found to be effective in 74% of the patients with exertional angina, whereas metoprolol was beneficial in 62%." | 2.67 | [Comparison of antianginal effects of diltiazem and metoprolol in patients with ischemic heart disease with different clinical forms of angina pectoris]. ( Guliev, AB; Iaroshevskaia, FM; Krutovskikh, IV; Lupanov, VP; Sidorenko, BA, 1990) |
| "More metoprolol-treated patients withdrew because of depression (6 vs less than 1%; p = 0." | 2.66 | Influence of beta 2 agonism and beta 1 and beta 2 antagonism on adverse effects and plasma lipoproteins: results of a multicenter comparison of dilevalol and metoprolol. ( Ahmad, S; Glasser, SP; Lucas, C; Lutz, LJ; Materson, BJ; Morledge, JH; Ramanathan, KB; Saunders, E; Schnaper, HW; Vlachakis, ND, 1989) |
| "Metoprolol treatment also attenuates circadian variation of silent ischemia." | 2.66 | Effects of titrated beta blockade (metoprolol) on silent myocardial ischemia in ambulatory patients with coronary artery disease. ( Coy, K; Imperi, GA; Lambert, CR; Lopez, L; Pepine, CJ, 1987) |
| "Nifedipine is a calcium antagonist with established anti-vasospastic action in man and, possibly cardioprotective effects during ischaemia." | 2.65 | Acute myocardial ischaemia: what information can be expected in the near future from ongoing clinical trials with nifedipine? ( Hugenholtz, PG; Lubsen, J, 1983) |
| "Metoprolol or placebo was gradually withdrawn during 1 week in 115 patients participating in a 3-year, double-blind, postinfarction study." | 2.65 | Rebound phenomena following gradual withdrawal of chronic metoprolol treatment in patients with ischemic heart disease. ( Hjemdahl, P; Olsson, G; Rehnqvist, N, 1984) |
| "All patients clinically had idiopathic dilated cardiomyopathy; however, at coronary angiography, four had occult coronary disease." | 2.65 | Oral beta-adrenergic blockade with metoprolol in chronic severe dilated cardiomyopathy. ( Anderson, ST; Currie, PJ; Federman, J; Harper, RW; Kelly, MJ; Lim, YL; McKenzie, A; Pitt, A, 1984) |
| "Type 2 diabetes is becoming very common and is closely linked to physical inactivity and obesity." | 2.41 | Beta-blockers and diabetes: the bad guys come good. ( Cruickshank, JM, 2002) |
| "The incidence of congestive heart failure is higher in diabetic patients, although the reasons for this increased rate are debated (higher incidence and severity of coronary heart disease and arterial hypertension, or a true diabetic cardiomyopathy)." | 2.41 | [Prevention and treatment of congestive heart failure in diabetic patients]. ( Anguita Sánchez, M, 2002) |
| " No adverse events resulted from rate control medication." | 1.35 | Safety and efficacy of a rate control protocol for cardiac CT. ( Roberts, WT; Timmis, AD; Timmis, JB; Wright, AR, 2009) |
| "Metoprolol treatment tended to normalize LV end-diastolic pressure (LVEDP)." | 1.30 | Comparative efficacy of a DA2/alpha2 agonist and a beta-blocker in reducing adrenergic drive and cardiac fibrosis in an experimental model of left ventricular dysfunction after coronary artery occlusion. ( Bernasconi, R; Bongrani, S; Calvillo, L; Fiordaliso, F; Jeremic, G; Latini, R; Luvarà, G; Masson, S; Razzetti, R; Rondelli, I; Torri, M, 1998) |
| "Indications for treatment were hypertension (75%), coronary artery disease with (12%) or without (3%) hypertension, or unknown (10%)." | 1.30 | Beta adrenergic blockers lower renin in patients treated with ACE inhibitors and diuretics. ( Danser, AH; Hense, HW; Holmer, SR; Mayer, B; Riegger, GA; Schunkert, H, 1998) |
| "Chronic treatment of heart failure patients with beta-adrenoceptor antagonists leads to an up-regulation of cardiac beta-adrenoceptors, but in a subtype-selective fashion: beta 1-selective antagonists increase only cardiac beta 1-adrenoceptors, whereas non-selective antagonists increase both beta 1- and beta 2-adrenoceptors." | 1.28 | Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors. ( Borst, HG; Brodde, OE; Maier, W; Michel, MC; Zerkowski, HR, 1989) |
| " However, the combined administration could lead to adverse effects through amplification of negative inotropic and chronotropic properties." | 1.28 | Acute hemodynamic and electrophysiologic effects and safety of high-dose intravenous diltiazem in patients receiving metoprolol. ( Kruijssen, DA; Look, MP; Remme, WJ; van Hoogenhuyze, DC; Wiesfeld, AC, 1992) |
| "Mean time to arrhythmia and death was 4." | 1.27 | The effect of beta blockers on cardiac neural discharge associated with coronary occlusion in the cat. ( Lathers, CM; Spivey, WH, 1987) |
| "In a sulfinpyrazone-treated group 3 out of 8, and in a metoprolol-treated group 2 out of 5 animals died." | 1.27 | Sudden death related to advanced coronary atherosclerosis in mini-pigs: influence of some drugs. ( Jacobsson, L; Lundholm, L; Wingren, G, 1984) |
| "A distinct phase of ventricular arrhythmias was evident about 10 to 30 min after ligation." | 1.27 | Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP. ( Gihwala, D; Hamm, CW; Muller, CA; Opie, LH; Peisach, M, 1986) |
| "Correspondingly, ventricular arrhythmias and fibrillation were almost completely prevented by metoprolol, d-sotalol or verapamil, but increased by lidocaine." | 1.27 | Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion. ( Gülker, H; Haverkamp, W; Hindricks, G; Thale, J, 1987) |
| "Metoprolol was injected intravenously in a dose of 0." | 1.27 | Effects of bisoprolol in relation to metoprolol and bufuralol on left ventricular hemodynamics at rest and during exercise in chronic ischemic heart disease. ( Burkart, F; Pfisterer, M; Steinmann, E, 1986) |
| "Metoprolol was found to be significantly more efficiently distributed to the ischemic myocardium than atenolol in all three species." | 1.27 | Cardiac anti-ischemic effect of metoprolol: role of beta-blockade within the ischemic region. ( Ablad, B; Abrahamsson, T; Adler, G; Björkman, JA; Bjurö, T; Ek, L; Ervik, M; Sjöquist, PO; Sutherland, I; Svensson, L, 1987) |
| "Metoprolol was administered at different times after the onset of ischemia to determine any relationship between antiarrhythmic effects and the time of administration." | 1.27 | The effect of beta-adrenoceptor blockade and of thromboxane synthetase inhibition, alone and in combination, on arrhythmias resulting from myocardial ischemia. ( Parratt, JR; Wainwright, CL, 1985) |
| "Resistance across the stenosis decreased significantly (p less than 0." | 1.26 | Changes in ischemic blood flow distribution and dynamic severity of a coronary stenosis induced by beta blockade in the canine heart. ( Buck, JD; Gross, GJ; Hardman, HF; Warltier, DC, 1981) |
| " There were statistically significant dose-response reductions in systolic and diastolic pressures, heart rate and cardiac output together with a dose-related increase in pulmonary wedge pressure." | 1.26 | Haemodynamic dose-response effects of i.v. metoprolol in coronary heart disease. ( Hendry, WG; Silke, B; Taylor, SH, 1981) |
| "Nifedipine was found to be valuable in stabilizing unstable angina persisting despite beta-blockade and nitrates." | 1.26 | Benefits from adding nifedipine to the treatment of unstable angina when beta-blockade and isosorbide dinitrate have proved inadequate. ( Hagemeijer, F; Santoso, T; van Mechelen, R, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 99 (50.77) | 18.7374 |
| 1990's | 59 (30.26) | 18.2507 |
| 2000's | 28 (14.36) | 29.6817 |
| 2010's | 7 (3.59) | 24.3611 |
| 2020's | 2 (1.03) | 2.80 |
| Authors | Studies |
|---|---|
| Meng, LL | 1 |
| Huang, W | 1 |
| Lu, Y | 1 |
| Wang, F | 1 |
| Ni, H | 1 |
| Sun, Y | 1 |
| Shi, H | 1 |
| Zhang, Y | 1 |
| Sun, N | 1 |
| Jiang, X | 1 |
| Xi, Y | 1 |
| Musikhina, NA | 1 |
| Gapon, LI | 1 |
| Utesheva, AB | 1 |
| Petelina, TI | 1 |
| Kolesnikova, SN | 1 |
| Kounis, NG | 1 |
| Davlouros, P | 1 |
| Fortmüller, U | 1 |
| Weintraub, WS | 1 |
| Spertus, JA | 1 |
| Kolm, P | 1 |
| Maron, DJ | 1 |
| Zhang, Z | 1 |
| Jurkovitz, C | 1 |
| Zhang, W | 1 |
| Hartigan, PM | 1 |
| Lewis, C | 1 |
| Veledar, E | 1 |
| Bowen, J | 1 |
| Dunbar, SB | 1 |
| Deaton, C | 1 |
| Kaufman, S | 1 |
| O'Rourke, RA | 1 |
| Goeree, R | 1 |
| Barnett, PG | 1 |
| Teo, KK | 1 |
| Boden, WE | 1 |
| Mancini, GB | 1 |
| Roberts, WT | 1 |
| Wright, AR | 1 |
| Timmis, JB | 1 |
| Timmis, AD | 1 |
| Priebe, HJ | 1 |
| Weingärtner, O | 1 |
| Böhm, M | 1 |
| Laufs, U | 1 |
| Ji, H | 1 |
| Guo, WZ | 1 |
| Yan, ZH | 1 |
| Li, D | 1 |
| Lu, CL | 1 |
| Gokce, N | 1 |
| Holbrook, M | 1 |
| Hunter, LM | 1 |
| Palmisano, J | 1 |
| Vigalok, E | 1 |
| Keaney, JF | 1 |
| Vita, JA | 1 |
| Anguita Sánchez, M | 1 |
| Cruickshank, JM | 1 |
| Taillefer, R | 1 |
| Ahlberg, AW | 1 |
| Masood, Y | 1 |
| White, CM | 1 |
| Lamargese, I | 1 |
| Mather, JF | 1 |
| McGill, CC | 1 |
| Heller, GV | 1 |
| Gerson, MC | 1 |
| Patel, MR | 1 |
| Gattis, W | 1 |
| Bell, DS | 1 |
| Huang, WY | 1 |
| Sun, M | 1 |
| Zhou, HY | 1 |
| Pei, ZF | 1 |
| Yang, TL | 1 |
| Nette, AF | 1 |
| Abraham, G | 1 |
| Ungemach, FR | 1 |
| Oertel, R | 1 |
| Kirch, W | 1 |
| Leineweber, K | 1 |
| Mohr, FW | 1 |
| Dhein, S | 1 |
| Yao, J | 1 |
| Lu, FX | 1 |
| Xu, D | 1 |
| Zhou, L | 1 |
| Yong, YH | 1 |
| Xu, J | 1 |
| Tang, XX | 1 |
| Ványi, J | 1 |
| Roy Parratt, J | 1 |
| Végh, A | 1 |
| Karagiannis, SE | 1 |
| Bax, JJ | 1 |
| Elhendy, A | 1 |
| Feringa, HH | 1 |
| Cokkinos, DV | 1 |
| van Domburg, R | 1 |
| Simoons, M | 1 |
| Poldermans, D | 2 |
| Lynch, T | 1 |
| Shapiro, MD | 1 |
| Pena, AJ | 1 |
| Nichols, JH | 1 |
| Worrell, S | 1 |
| Bamberg, F | 1 |
| Dannemann, N | 1 |
| Abbara, S | 1 |
| Cury, RC | 1 |
| Brady, TJ | 1 |
| Hoffmann, U | 1 |
| Dufour Doiron, M | 1 |
| Prud'homme, D | 1 |
| Boulay, P | 1 |
| Fox, K | 1 |
| Borer, JS | 2 |
| Camm, AJ | 1 |
| Danchin, N | 1 |
| Ferrari, R | 1 |
| Lopez Sendon, JL | 1 |
| Steg, PG | 1 |
| Tardif, JC | 1 |
| Tavazzi, L | 1 |
| Tendera, M | 1 |
| Zhang, Q | 1 |
| Lu, XN | 1 |
| Sun, NL | 1 |
| Fleisher, LA | 1 |
| Johansson, SR | 1 |
| McCall, M | 1 |
| Wilhelmsson, C | 2 |
| Vedin, JA | 1 |
| Merker, R | 1 |
| Schwittek, W | 1 |
| Kladetzky, RG | 1 |
| Kuhn, H | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| CSP #424 - Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation[NCT00007657] | Phase 3 | 3,260 participants (Anticipated) | Interventional | 1998-12-31 | Completed | ||
| Quality of Life and Achievement of Target of Treatment After Optimized Medical Treatment, Physical Training and Smoking Cessation With or Without Percutaneous Coronary Intervention in Patients With Stable Angina Pectoris.[NCT00825604] | Phase 2 | 0 participants (Actual) | Interventional | 2009-01-31 | Withdrawn (stopped due to Because of poor inclusion difficulties to find patient) | ||
| Impact of Coronary Artery Stenting on Quantitative Myocardial Blood Flow and Health Status[NCT04475094] | 75 participants (Anticipated) | Observational | 2019-12-23 | Recruiting | |||
| Heart Rate Controller in Computed Tomography Coronary Angiography: A Randomized Controlled Trial of Metoprolol, Diltiazem and Ivabradine[NCT05261464] | Phase 4 | 246 participants (Anticipated) | Interventional | 2021-01-30 | Recruiting | ||
| A Single Centre, Retrospective Cohort Study on Post Analysis on the Link Between the Clinical Heart Rate and Outcomes During PCI[NCT02351674] | 15,000 participants (Anticipated) | Observational | 2015-01-31 | Not yet recruiting | |||
| Heart Rate Lowering Efficacy and Respiratory Safety of Ivabradine in Patients With Obstructive Airway Disease[NCT01365286] | Phase 4 | 40 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| Bisoprolol Plasma Residual Concentrations for the Optimization of Drug Management in Heart Failure With Mild to Reduced Ejection Fraction[NCT03644446] | 81 participants (Anticipated) | Observational [Patient Registry] | 2017-11-02 | Recruiting | |||
| "PGDT With the Hypotension Prediction Index to Reduce the Number and Duration of Intraoperative Hypotension and the Incidence of Renal Failure in Patients Undergoing Lung Surgery"[NCT04149314] | 142 participants (Actual) | Interventional | 2019-11-20 | Completed | |||
| Impedance Measurement of Epicardial Substrate for Ventricular Arrhythmias: Case Control Series of Patients With and Without Myocardial Scarring[NCT00291174] | 8 participants (Actual) | Observational | 2006-04-30 | Terminated (stopped due to Unforeseen difficulty identifying and enrolling eligible subjects) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 reviews available for metoprolol and Coronary Heart Disease
| Article | Year |
|---|---|
A meta-analysis of wenxin granule and metoprolol for the treatment of coronary heart disease and arrhythmia.
Topics: Aged; Coronary Disease; Drugs, Chinese Herbal; Humans; Metoprolol; Multicenter Studies as Topic; Ven | 2022 |
Comparative efficacy of β-blockers on mortality and cardiovascular outcomes in patients with hypertension: a systematic review and network meta-analysis.
Topics: Adrenergic beta-Antagonists; Age Factors; Antihypertensive Agents; Atenolol; Coronary Disease; Human | 2017 |
Influence of beta-blockers on the outcome of at risk patients.
Topics: Adrenergic beta-Antagonists; Cohort Studies; Contraindications; Coronary Disease; Double-Blind Metho | 2009 |
[Prevention and treatment of congestive heart failure in diabetic patients].
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II; Angiotensin | 2002 |
Beta-blockers and diabetes: the bad guys come good.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Bisoprolol; Coronary Disease; Diabet | 2002 |
Advantages of a third-generation beta-blocker in patients with diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Coronary Disease; Diabetes Complications; Human | 2004 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Beta-adrenergic antagonists in the treatment of patients with heart disease.
Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca | 1981 |
Beta blocking agents: current status in the prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary D | 1982 |
Short- and long-term influence of beta-adrenergic antagonists after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Clinical Trials as Topic; Coronary Disease; Do | 1984 |
The role of beta-adrenergic receptor antagonists in the prevention of sudden cardiac death.
Topics: Action Potentials; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Calcium; Calcium Channel Block | 1984 |
[Exertion hypertension in coronary disease and its importance in prevention and rehabilitation].
Topics: Adult; Coronary Disease; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle | 1982 |
[Treatment with beta-blockers in patients with acute coronary syndrome].
Topics: Acute Disease; Adrenergic beta-Antagonists; Angina, Unstable; Atenolol; Clinical Trials as Topic; Co | 1998 |
[Long-term utilization of beta-blockers in arterial hypertension].
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Blood Pressure; Coronary Disease; Drug Toleranc | 1978 |
Drug therapy: metoprolol.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Hemodynamics; Humans; Hypertension; | 1979 |
Controlled release metoprolol formulations. A review of their pharmacodynamic and pharmacokinetic properties, and therapeutic use in hypertension and ischaemic heart disease.
Topics: Biological Availability; Coronary Disease; Delayed-Action Preparations; Dose-Response Relationship, | 1992 |
Beta 1-blockade and acute coronary ischemia. Possible role of platelets.
Topics: Acute Disease; Animals; Blood Platelets; Coronary Disease; Electrocardiography; Exercise; Humans; Me | 1991 |
Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders.
Topics: Adult; Age Factors; Aged; Arrhythmias, Cardiac; Cardiomegaly; Coronary Disease; Drug Interactions; D | 1986 |
Massive metoprolol ingestion associated with a fatality--a case report.
Topics: Adult; Chromatography, Gas; Coronary Disease; Humans; Male; Metoprolol; Myocardium; Spectrophotometr | 1987 |
81 trials available for metoprolol and Coronary Heart Disease
| Article | Year |
|---|---|
[Cerebral blood flow and endothelial functional activity in patients with coronary heart disease and arterial hypertension during therapy with ivabradine in combination with perindopril].
Topics: Benzazepines; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiovasc | 2012 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Acute effects of vasoactive drug treatment on brachial artery reactivity.
Topics: Adult; Analysis of Variance; Brachial Artery; Cardiovascular Agents; Coronary Disease; Double-Blind | 2002 |
Acute beta-blockade reduces the extent and severity of myocardial perfusion defects with dipyridamole Tc-99m sestamibi SPECT imaging.
Topics: Adrenergic beta-Antagonists; Coronary Disease; Dipyridamole; Double-Blind Method; Exercise Test; Fem | 2003 |
Reduction in dipyridamole-induced single-photon emission computed tomography myocardial defect size by beta-blockers: time to re-examine the patient preparation protocol for pharmacologic stress testing.
Topics: Adrenergic beta-Antagonists; Coronary Disease; Dipyridamole; Double-Blind Method; Exercise Test; Hum | 2003 |
Interaction between simvastatin and metoprolol with respect to cardiac beta-adrenoceptor density, catecholamine levels and perioperative catecholamine requirements in cardiac surgery patients.
Topics: Adrenergic beta-Antagonists; Aged; Atrial Appendage; Blood Pressure; Cardiac Surgical Procedures; Ca | 2005 |
[Effects of Verapamil and Metoprolol on heart rate variability in patients with coronary heart disease].
Topics: Anti-Arrhythmia Agents; Coronary Disease; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; | 2007 |
Perioperative beta blockade: where do we go from here?
Topics: Adrenergic beta-Antagonists; Coronary Disease; Humans; Hypotension; Intraoperative Care; Intraoperat | 2008 |
Duration of action of beta blockers.
Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Ra | 1980 |
Intravenous beta-blockade in coronary heart disease: is cardioselectivity or intrinsic sympathomimetic activity hemodynamically useful?
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Hear | 1982 |
Beta blocking agents: current status in the prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary D | 1982 |
The influence of beta-adrenoceptor antagonists with and without intrinsic sympathomimetic activity on local wall motion abnormalities in patients with coronary heart disease.
Topics: Adrenergic beta-Antagonists; Adult; Cardiac Catheterization; Cineangiography; Coronary Disease; Fema | 1982 |
[Influence of betablocking agents with and without intrinsic sympathicomimetic activity (ISA) on local wall-motion disorders in patients with coronary heart disease].
Topics: Adrenergic beta-Antagonists; Adult; Coronary Disease; Female; Heart; Hemodynamics; Humans; Male; Met | 1982 |
Beta blockers in ischemic heart disease.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Humans | 1983 |
[Beta receptor blockers and calcium antagonists in coronary disease. Differential therapeutic aspects].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blocke | 1983 |
Oral beta-adrenergic blockade with metoprolol in chronic severe dilated cardiomyopathy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiomyopathy, Dila | 1984 |
Short- and long-term influence of beta-adrenergic antagonists after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Clinical Trials as Topic; Coronary Disease; Do | 1984 |
Metoprolol medication and coronary artery bypass grafting operation.
Topics: Anesthesia, Intravenous; Blood Pressure; Cardiac Output; Coronary Artery Bypass; Coronary Disease; F | 1984 |
Long-term metoprolol therapy and neuroleptanesthesia in coronary artery surgery: withdrawal versus maintenance of beta 1-adrenoreceptor blockade.
Topics: Aged; Clinical Trials as Topic; Coronary Disease; Electrocardiography; Female; Hemodynamics; Humans; | 1983 |
Acute myocardial ischaemia: what information can be expected in the near future from ongoing clinical trials with nifedipine?
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Electrocardiography; Humans; Metoprolol | 1983 |
[Metoprolol in the treatment of coronary disease].
Topics: Adult; Clinical Trials as Topic; Coronary Disease; Humans; Male; Metoprolol; Middle Aged | 1983 |
[Evaluation of the effects of slow-release metoprolol in chronic coronary insufficiency].
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Delayed-Action Preparations; Dou | 1983 |
Comparative effects of nitroglycerin, nifedipine and metoprolol on regional left ventricular function in patients with one-vessel coronary disease.
Topics: Adult; Aged; Cardiac Output; Coronary Disease; Coronary Vessels; Female; Heart Ventricles; Hemodynam | 1983 |
Influence of propranolol, metoprolol, and pindolol on mucociliary clearance in patients with coronary heart disease.
Topics: Adult; Aged; Bronchi; Cilia; Coronary Disease; Female; Humans; Lung; Male; Metoprolol; Middle Aged; | 1984 |
Rebound phenomena following gradual withdrawal of chronic metoprolol treatment in patients with ischemic heart disease.
Topics: Aged; Blood Pressure; Catecholamines; Coronary Disease; Double-Blind Method; Exercise Test; Female; | 1984 |
[Calcium antagonists and primary prevention of coronary disease].
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Double-Blind Method; Female; Humans; Male; Metoprolo | 1995 |
ST segment tracking for rapid determination of patency of the infarct-related artery in acute myocardial infarction.
Topics: Anistreplase; Cardiac Catheterization; Confidence Intervals; Coronary Angiography; Coronary Disease; | 1995 |
[Increased vagal activity after administration of the calcium antagonist diltiazem in patients with coronary heart disease].
Topics: Aged; Arrhythmia, Sinus; Coronary Disease; Diltiazem; Electrocardiography; Heart Rate; Homeostasis; | 1995 |
Effect of beta-blockade on baroreflex sensitivity and cardiovascular autonomic function tests in patients with coronary artery disease.
Topics: Adult; Aged; Atenolol; Autonomic Nervous System; Baroreflex; Blood Pressure; Coronary Disease; Cross | 1994 |
Acute influence of beta-adrenergic antagonists on left ventricular diastolic function: contrasting results after administration of celiprolol and metoprolol.
Topics: Adrenergic beta-Antagonists; Adult; Celiprolol; Coronary Disease; Double-Blind Method; Heart; Humans | 1994 |
Beneficial effects of beta-adrenergic blockade in coronary artery surgery: clinical research.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiotonic Agents; Coronary A | 1993 |
Beneficial effects of metoprolol in heart failure associated with coronary artery disease: a randomized trial.
Topics: Coronary Disease; Double-Blind Method; Female; Heart Failure; Humans; Male; Metoprolol; Middle Aged; | 1994 |
Effect of beta-blockade on heart rate variability in patients with coronary artery disease.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Atenolol; Circadian Rhythm; Coronary Disease; Double- | 1994 |
Absence of beneficial effect of intravenous metoprolol given during angioplasty in patients with single-vessel coronary artery disease.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Chest Pain; Coronary Disease; Double-Blind Method; Elec | 1993 |
Power spectral analysis of heart rate in elderly hypertensive subjects with or without silent coronary disease.
Topics: Aged; Algorithms; Amlodipine; Antihypertensive Agents; Case-Control Studies; Coronary Disease; Doubl | 1996 |
Effect of metoprolol on death and cardiac events during a 2-year period after coronary artery bypass grafting. The MACB Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Coronary Artery Bypass | 1995 |
Effect of atenolol or metoprolol on arbutamine stress echocardiography in patients suspected of having coronary artery disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Coronary Disease; Echocardiography; Exercise Test; Female; He | 1998 |
Autonomic dysfunction in patients with mild heart failure and coronary artery disease and the effects of add-on beta-blockade.
Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Autonomic Nervous System; Case-Control Stu | 2001 |
Effect of metoprolol and d,l-sotalol on microvolt-level T-wave alternans. Results of a prospective, double-blind, randomized study.
Topics: Adrenergic beta-Antagonists; Aged; Anti-Arrhythmia Agents; Cause of Death; Coronary Disease; Death, | 2001 |
Effects of beta-blockers on sexual performance in men with coronary heart disease. A prospective, randomized and double blinded study.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Coronary Disease; Erectile Dysfunction; | 2001 |
Metoprolol treatment to prevent restenosis following percutaneous transluminal coronary angioplasty.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Angioplasty, Balloon, Coronary; Coronary Disea | 2002 |
Hemodynamic effects of two cardioselective beta-adrenoceptive antagonists, metoprolol and H 87/07, in coronary insufficiency.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Output; Coronary Disease; Female; Heart | 1976 |
Acute influence of different beta-blocking agents upon left heart hemodynamics at rest and during exercise in patients with coronary artery disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Coronary Disease; Exercise Test; Female; H | 1979 |
[Wake up time, thrombocyte aggregation and the risk of acute coronary heart disease. The TRIMM (Trigger and Mechanisms of Myocardial Infarct) Study Group].
Topics: Aged; Blood Pressure Monitors; Circadian Rhythm; Coronary Disease; Double-Blind Method; Epinephrine; | 1992 |
Improved working capacity in patients with ischaemic heart disease during a 10-day treatment with oral theophylline.
Topics: Administration, Oral; Aged; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; Exerci | 1992 |
Effect of beta-blockade on low heart rate-related ischemia during mental stress.
Topics: Adrenergic beta-Antagonists; Aged; Coronary Disease; Differential Threshold; Exercise; Female; Habit | 1991 |
Acute haemodynamic profile of celiprolol in patients with coronary heart disease and hypertension: a double-blind comparison with metoprolol.
Topics: Adrenergic beta-Antagonists; Adult; Celiprolol; Coronary Circulation; Coronary Disease; Double-Blind | 1991 |
Coronary artery disease can be prevented by antihypertensive therapy: experiences from the MAPHY Study.
Topics: Adult; Antihypertensive Agents; Benzothiadiazines; Cerebrovascular Disorders; Coronary Disease; Deat | 1990 |
Attenuation of circadian variation by combined antianginal therapy with suppression of morning and evening increases in transient myocardial ischemia.
Topics: Angina Pectoris; Circadian Rhythm; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; | 1991 |
[Preoperative treatment with beta-receptor blockers and isoflurane anesthesia. Hemodynamic interactions in patients with coronary disease].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Anesthesia, Inhalation; Atenolol; Bisoprolol; Coronary Dis | 1990 |
[Effectiveness of various combination therapies in patients with coronary heart disease].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Diltiazem; Double-Blind Met | 1990 |
Metoprolol versus thiazide diuretics in hypertension. Morbidity results from the MAPHY Study.
Topics: Adult; Benzothiadiazines; Blood Pressure; Cardiovascular Diseases; Coronary Artery Bypass; Coronary | 1991 |
Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine.
Topics: Angina Pectoris; Circadian Rhythm; Coronary Angiography; Coronary Disease; Double-Blind Method; Elec | 1991 |
[The use of metoprolol with calcium antagonists of different mechanisms of action (diltiazem and nifedipine) in patients with stenocardia of effort].
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Diltiazem; Drug Therapy, Combina | 1990 |
[Comparison of antianginal effects of diltiazem and metoprolol in patients with ischemic heart disease with different clinical forms of angina pectoris].
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Diltiazem; Humans; Metoprolol; Middle Aged; Randomiz | 1990 |
Effects of benazepril and metoprolol OROS alone and in combination on myocardial ischemia in patients with chronic stable angina.
Topics: Adult; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Coronary Disea | 1990 |
Hemodynamic effects at rest and during exercise of combined alpha/beta-receptor blockade and of beta-receptor blockade alone in patients with ischemic heart disease.
Topics: Coronary Disease; Hemodynamics; Humans; Labetalol; Male; Metoprolol; Middle Aged; Physical Exertion; | 1987 |
[Dose-dependent anti-arrhythmia effect of retard metoprolol in coronary disease patients with ventricular arrhythmia].
Topics: Adult; Cardiac Complexes, Premature; Clinical Trials as Topic; Coronary Disease; Delayed-Action Prep | 1988 |
Noradrenergic activity and silent ischaemia in hypertensive patients with stable angina: effect of metoprolol.
Topics: Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; El | 1989 |
Influence of beta 2 agonism and beta 1 and beta 2 antagonism on adverse effects and plasma lipoproteins: results of a multicenter comparison of dilevalol and metoprolol.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Cholesterol; Coronary Disease; Double-B | 1989 |
Beta-blockers and diuretics. The HAPPHY and MAPHY studies.
Topics: Adrenergic beta-Antagonists; Arteriosclerosis; Benzothiadiazines; Cerebrovascular Disorders; Coronar | 1989 |
Suppression of silent ischemia by metoprolol without alteration of morning increase of platelet aggregability in patients with stable coronary artery disease.
Topics: Aged; Circadian Rhythm; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Electrocard | 1989 |
Decreased coronary heart disease in hypertensive smokers. Mortality results from the MAPHY study.
Topics: Adult; Benzothiadiazines; Coronary Disease; Diuretics; Follow-Up Studies; Humans; Hypertension; Male | 1989 |
Hemodynamic and adrenergic effects of combined alpha/beta-receptor blockade versus combined beta-receptor and slow channel calcium blockade in patients with ischemic heart disease.
Topics: Adult; Aged; Blood Pressure; Coronary Disease; Drug Therapy, Combination; Exercise Test; Hemodynamic | 1989 |
Influence of beta-adrenergic blockade defined by time series analysis on circadian variation of heart rate and ambulatory myocardial ischemia.
Topics: Circadian Rhythm; Coronary Disease; Electrocardiography, Ambulatory; Fourier Analysis; Heart Rate; H | 1989 |
Beta blockade and intermittent claudication.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Coronary Disease; Female; Gait; | 1985 |
Differential hemodynamic effects of beta-adrenoceptor blockers, Ca antagonists and combined alpha-beta-receptor blockade in ischemic heart disease.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; | 1986 |
Critical comments on recent literature. SCRAAPHY about MAPHY from HAPPHY.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Benzothiadiazines; Clinical Protocols; Coronary Diseas | 1988 |
QRS-amplitudes during antihypertensive treatment: a comparison between beta-blocker and thiazide diuretic regimens.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; Electrocardio | 1986 |
[Modification of the autonomic vascular reaction and peripheral circulation in the handgrip and orthostasis test by beta-blockage in patients with and without peripheral arterial occlusive disease].
Topics: Adult; Aged; Arousal; Arterial Occlusive Diseases; Blood Pressure; Celiprolol; Clinical Trials as To | 1988 |
[Possibilities and limitations of selective beta 1 adrenergic receptor blockade in clinical practice].
Topics: Adult; Aged; Bradycardia; Bronchi; Bronchial Spasm; Clinical Trials as Topic; Coronary Disease; Dose | 1988 |
Primary prevention in patients with hypertension: comments on the clinical implications of the MAPHY Study. Metoprolol Atherosclerosis Prevention in Hypertensives Study.
Topics: Adult; Cause of Death; Clinical Trials as Topic; Coronary Disease; Diuretics; Drug Therapy, Combinat | 1988 |
Primary prevention with metoprolol in patients with hypertension. Mortality results from the MAPHY study.
Topics: Adult; Benzothiadiazines; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Diur | 1988 |
Left ventricular function following withdrawal of chronic metoprolol treatment in patients with ischaemic heart disease. A double blind study.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Echocardiogra | 1986 |
Effects of titrated beta blockade (metoprolol) on silent myocardial ischemia in ambulatory patients with coronary artery disease.
Topics: Aged; Circadian Rhythm; Coronary Disease; Double-Blind Method; Electrocardiography; Heart Rate; Huma | 1987 |
A haemodynamic study of the effects of combined slow-calcium channel blockade (nisoldipine) and beta-blockade (metoprolol) in coronary heart disease.
Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Hemod | 1986 |
Abstracts of papers presented at an international symposium on the role of beta-blockade in acute myocardial ischaemia and infarction, Rome, October 29-30, 1984.
Topics: Clinical Trials as Topic; Coronary Disease; Humans; Metoprolol; Myocardial Infarction | 1985 |
Left ventricular performance in unstable angina: assessment with radionuclide techniques.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Angiography; Coronary Disease; | 1985 |
[Effect of metoprolol duriles in chronic coronary insufficiency].
Topics: Adult; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Coronary Disease; Delayed-Action P | 1985 |
Effect of short and long term administration of amiodarone on ischaemia-induced left ventricular dysfunction. Implications for combined antianginal drug therapy.
Topics: Adult; Amiodarone; Angina Pectoris; Benzofurans; Coronary Disease; Female; Hemodynamics; Humans; Mal | 1985 |
Haemodynamic analysis of the effects of nicardipine and metoprolol alone and in combination in coronary artery disease.
Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Femal | 1985 |
97 other studies available for metoprolol and Coronary Heart Disease
| Article | Year |
|---|---|
Observation of Curative Effect of Trimetazidine Combined with Metoprolol in Elderly Patients with Coronary Heart Disease Complicated with Heart Failure and the Effect of Myocardial Remodeling by Integrated Traditional Chinese and Western Medicine.
Topics: Aged; Cardiovascular Diseases; China; Coronary Disease; Glucose; Heart Failure; Humans; Metoprolol; | 2022 |
Bleeding complication with dual antiplatelet therapy: spontaneous uvula hematoma.
Topics: Aged, 80 and over; Aspirin; Clopidogrel; Coronary Disease; Drug Interactions; Hematoma; Humans; Lary | 2014 |
[First fixed combination becomes available].
Topics: Angina Pectoris; Benzazepines; Coronary Disease; Drug Combinations; Humans; Ivabradine; Metoprolol | 2016 |
[Anti-angina fixed combination is available].
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Benzazepines; Cardiovascular Agents; Combined Modal | 2016 |
[Increased physical capacity].
Topics: Angina Pectoris; Benzazepines; Cardiovascular Agents; Clinical Trials as Topic; Coronary Disease; Do | 2016 |
Safety and efficacy of a rate control protocol for cardiac CT.
Topics: Anti-Arrhythmia Agents; Artifacts; Clinical Protocols; Coronary Angiography; Coronary Disease; Dose- | 2009 |
[67-year-old patient with abdominal pain and pronounced peritonitis].
Topics: Abdominal Pain; Aged; Angioedema; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; | 2009 |
Influence of drug treatment on glucocorticoid receptor levels in patients with coronary heart disease.
Topics: Aged; Blotting, Western; Coronary Disease; Female; Humans; Isosorbide Dinitrate; Lovastatin; Male; M | 2010 |
Which beta-blocker for heart failure?
Topics: Adrenergic beta-Antagonists; Bisoprolol; Carbazoles; Carvedilol; Contraindications; Coronary Disease | 2004 |
[Effect of the polymorphism of the angiotensin-converting enzyme gene on the drug treatment in patients with chronic heart failure].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Benz | 2004 |
[Value of metoprolol injection at dobutamine-atropine stress echocardiography for detection of coronary artery disease].
Topics: Aged; Coronary Disease; Echocardiography, Stress; Female; Humans; Male; Metoprolol; Middle Aged; Pre | 2005 |
Metoprolol reduces 'compensatory' coronary blood flow following occlusion of an adjacent branch without altering post-occlusion hyperaemia.
Topics: Adrenergic beta-Antagonists; Algorithms; Animals; Coronary Circulation; Coronary Disease; Dogs; Elec | 2006 |
Enhanced sensitivity of dobutamine stress echocardiography by observing wall motion abnormalities during the recovery phase after acute beta-blocker administration.
Topics: Adrenergic beta-Antagonists; Coronary Angiography; Coronary Disease; Dobutamine; Echocardiography, S | 2006 |
Medication costs as a primary cause of nonadherence in the elderly.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Coronary Disease; Costs and C | 2006 |
Efficacy of pre-scan beta-blockade and impact of heart rate on image quality in patients undergoing coronary multidetector computed tomography angiography.
Topics: Adrenergic beta-Antagonists; Artifacts; Chi-Square Distribution; Contrast Media; Coronary Angiograph | 2008 |
Time-of-day variation in cardiovascular response to maximal exercise testing in coronary heart disease patients taking a beta-blocker.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Pressure; Cardiovascular System; Circadian | 2007 |
[Serum lipid levels under chronical treatment with beta-receptor blocking agents in patients with coronary artery disease (author's transl)].
Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Cholesterol; Coronary Disease; Diabetes Mellitus; Hum | 1981 |
Changes in ischemic blood flow distribution and dynamic severity of a coronary stenosis induced by beta blockade in the canine heart.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Constriction, Pathologic; Coronary Circulation | 1981 |
Reversible renal failure: associated with treatment with a beta-adrenergic receptor blocking drug and non-steroidal anti-inflammatory drugs.
Topics: Acute Kidney Injury; Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Arthritis, Rheumatoid; C | 1982 |
Acute myocardial infarction: selective or ISA-type beta-adrenoceptor blocking drug?
Topics: Adrenergic beta-Antagonists; Coronary Disease; Humans; Metoprolol; Myocardial Infarction; Pindolol; | 1982 |
Protective effects on isolated hearts with developing infarction: slow channel blockade by diltiazem versus beta-adrenoceptor antagonism by metoprolol.
Topics: Adrenergic beta-Antagonists; Animals; Benzazepines; Calcium Channel Blockers; Cardiac Output; Cardia | 1982 |
Adverse interaction between beta-adrenergic blocking drugs and verapamil--report of three cases.
Topics: Adrenergic beta-Antagonists; Aged; Bradycardia; Coronary Disease; Drug Interactions; Drug Therapy, C | 1982 |
Secondary prevention after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Coronary Disease; Humans; Metoprolol; Myocardial Infarction; Prognosis; | 1982 |
Haemodynamic dose-response effects of intravenous beta-blocking drugs with different ancillary properties in patients with coronary heart disease.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Output; Coronary Disease; Dose-Response | 1982 |
The effect of alpha- and beta-adrenoceptor antagonist agents on reperfusion ventricular fibrillation and metabolic status in the isolated perfused rat heart.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arterial Occlusive Diseases; Ate | 1983 |
[Secondary prevention of myocardial infarct with beta blockers].
Topics: Adrenergic beta-Antagonists; Coronary Circulation; Coronary Disease; Humans; Metoprolol; Myocardial | 1983 |
Autoradiographic characterization of beta adrenergic receptors in coronary blood vessels and myocytes in normal and ischemic myocardium of the canine heart.
Topics: Animals; Arteries; Arterioles; Autoradiography; Coronary Disease; Coronary Vessels; Dihydroalprenolo | 1984 |
Treatment of unstable angina with emphasis on calcium antagonists.
Topics: Angina Pectoris; Angina, Unstable; Anticoagulants; Coronary Circulation; Coronary Disease; Electroca | 1984 |
Antianginal drug effects on normal, ischemic and scar myocardial segments in man.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Female; Heart; Humans; Male; Metoprolol; Middle Aged | 1984 |
Sudden death related to advanced coronary atherosclerosis in mini-pigs: influence of some drugs.
Topics: Animals; Cholesterol; Coronary Circulation; Coronary Disease; Coronary Vessels; Creatine Kinase; Dea | 1984 |
Different effects of metoprolol and chlorthalidone on serum lipoprotein levels in mild hypertension. Possible implications for coronary heart disease risk status.
Topics: Body Weight; Chlorthalidone; Cholesterol; Coronary Disease; Female; Heart Rate; Humans; Hypertension | 1984 |
Effects of three bradycardiac drugs on regional myocardial blood flow and function in areas distal to a total or partial coronary occlusion in dogs.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Collateral Circulation; Coronary Circulation; Coron | 1984 |
The influence of propranolol, metoprolol, and mepindolol on mucociliary clearance in coronary heart disease patients without pulmonary disease.
Topics: Cilia; Coronary Disease; Female; Humans; Lung; Lung Diseases; Male; Metoprolol; Middle Aged; Mucous | 1984 |
[Electrocardiographic differential diagnosis of ischemic and aspecific anomalies of ventricular repolarization].
Topics: Adult; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Female; Humans; Male; | 1980 |
Benefits from adding nifedipine to the treatment of unstable angina when beta-blockade and isosorbide dinitrate have proved inadequate.
Topics: Aged; Angina Pectoris, Variant; Coronary Disease; Coronary Vasospasm; Drug Therapy, Combination; Fem | 1982 |
[Anomalies of ventricular repolarization in asymptomatic subjects and angina patients. Possibility of differential diagnosis with pharmacological tests].
Topics: Adult; Blood Pressure; Coronary Disease; Diagnosis, Differential; Electrocardiography; Exercise Test | 1982 |
Hemodynamic consequences of combined beta-adrenergic and slow calcium channel blockade in man.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Drug Therapy, Combination; Electrocardiography; Fema | 1982 |
Haemodynamic dose-response effects of i.v. metoprolol in coronary heart disease.
Topics: Adult; Coronary Disease; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Injections, | 1981 |
[Role of calcium antagonists in therapy of coronary heart disease. Experimental report on the calcium antagonist fendiline, and the beta receptor blockader metoprolol].
Topics: Adult; Aged; Calcium; Coronary Disease; Drug Tolerance; Female; Fendiline; Humans; Male; Metoprolol; | 1980 |
Atrial ectopic activity and atrial fibrillation/flutter after coronary artery bypass surgery. A case-base study controlling for confounding from age, beta-blocker treatment, and time distance from operation.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Atrial Fibrillation; Atrial Flutter; Autonomi | 1995 |
[Beta-receptor blockers after revascularization in coronary sclerosis].
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Coronary Artery Bypass; Coronary Diseas | 1995 |
Doppler sonographic examination of the internal mammary artery graft: influence of exercise.
Topics: Adult; Aged; Angina Pectoris; Blood Flow Velocity; Coronary Disease; Echocardiography, Doppler; Exer | 1993 |
Primary prevention in patients with coronary heart disease: the APSIS study.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Female; Hu | 1995 |
Pharmacological effects of antianginal drugs on heart rate variability (HRV) and blood pressure variability (BPV) in patients with coronary artery disease (CAD).
Topics: Aged; Blood Pressure; Cardiovascular Agents; Coronary Disease; Diltiazem; Electrocardiography; Heart | 1996 |
Comparison of nifedipine and metoprolol on collateral coronary blood flow in a swine model of chronic coronary obstruction and acute ischaemia during isoflurane anaesthesia.
Topics: Adrenergic beta-Antagonists; Anesthetics, Inhalation; Animals; Calcium Channel Blockers; Chronic Dis | 1996 |
Comparative efficacy of a DA2/alpha2 agonist and a beta-blocker in reducing adrenergic drive and cardiac fibrosis in an experimental model of left ventricular dysfunction after coronary artery occlusion.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Catechol | 1998 |
Beta adrenergic blockers lower renin in patients treated with ACE inhibitors and diuretics.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Bisoprolol; C | 1998 |
Alpha-adrenoceptor blockade prevents exercise-induced vasoconstriction of stenotic coronary arteries.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Cardiac Catheteriz | 1999 |
Meeting highlights. Highlights of the 48th scientific sessions of the American College of Cardiology.
Topics: Abciximab; Alanine; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Antibo | 1999 |
Hypotension in patients with coronary disease: can profound hypotensive events cause myocardial ischaemic events?
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Blood Pressure Monitoring, Amb | 1999 |
Prospective clinical evaluation and follow-up of a cohort of consecutive VT/VF patients, using a staged-care protocol, including coronary arteriography, programmed electrical stimulation and cardiac surgery.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Cardiac Catheterization; Cardiac | 1999 |
[Clinical study on treatment of mild-middle degree congestive heart failure with integrated traditional Chinese and Western medicine].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Captopril; Coronary Disease; Drug Therapy, Combination; Dr | 2000 |
Different effects of carvedilol, metoprolol, and propranolol on left ventricular remodeling after coronary stenosis or after permanent coronary occlusion in rats.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Ascorbic Acid; Carbazoles; Cardi | 2002 |
[Significance of the changes of plasma endothelin, norepinephrine and atrial natriuretic peptide in treatment of heart failure with beta-blocker].
Topics: Adrenergic beta-Antagonists; Adult; Atrial Natriuretic Factor; Coronary Disease; Endothelins; Female | 1999 |
[The effect of nitroglycerin and of a new beta-blocking agent (metroprlolo) on exercise tolerance in ischemic patients].
Topics: Adult; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Female; Hemodynamics; | 1978 |
Effect of beta-blockade by metoprolol on global and regional left ventricular myocardial perfusion in coronary heart disease.
Topics: Adult; Blood Pressure; Coronary Circulation; Coronary Disease; Heart Rate; Heart Ventricles; Humans; | 1978 |
[Therapy of coronary disease].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Aspirin; Calcium Channel Blockers; Clinical Trials as | 1992 |
Acute hemodynamic and electrophysiologic effects and safety of high-dose intravenous diltiazem in patients receiving metoprolol.
Topics: Coronary Disease; Diltiazem; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Fema | 1992 |
Acute effects of combined alpha/beta-adrenoceptor blockade v combined beta-receptor and slow channel calcium blockade in ischemic heart disease complicated by hypertension. Hemodynamic and adrenergic responses.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiac Output; | 1991 |
Preservation of membrane phospholipids by propranolol, pindolol, and metoprolol: a novel mechanism of action of beta-blockers.
Topics: Adrenergic beta-Antagonists; Animals; Coronary Circulation; Coronary Disease; Creatine Kinase; Fatty | 1991 |
Pronounced accumulation of metoprolol in ischemic myocardium after coronary venous retroinfusion.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Coronary Vessels; Female; Heart Rat | 1990 |
Effect of antiischemic therapy on coronary flow reserve and the pressure-maximal coronary flow relationship in anesthetized swine.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Benzeneacetamides; Blood Pressure; Coronary Circul | 1991 |
Pharmacokinetic analysis of coronary sinus retroinfusion in pigs. Ischemic myocardial concentrations in the left circumflex coronary arterial area using metoprolol as a tracer.
Topics: Animals; Coronary Disease; Coronary Vessels; Female; Hemodynamics; Infusions, Intravenous; Male; Met | 1991 |
Pharmacokinetic analysis of coronary venous retroinfusion: a comparison with anterograde coronary artery drug administration using metoprolol as a tracer.
Topics: Animals; Cardiac Catheterization; Coronary Disease; Coronary Vessels; Female; Infusions, Intravenous | 1991 |
A possible acute MI: what location and type?
Topics: Aspirin; Coronary Angiography; Coronary Disease; Drug Therapy, Combination; Electrocardiography; Eme | 1991 |
Incidence of sudden cardiac death associated with coronary artery occlusion in dogs with hypertension and left ventricular hypertrophy is reduced by chronic beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Death, S | 1990 |
End-systolic regional wall stress-length and stress-shortening relations in an experimental model of normal, ischemic and reperfused myocardium.
Topics: Animals; Coronary Disease; Dobutamine; Dogs; Echocardiography; Female; Fluid Therapy; Male; Metoprol | 1991 |
[Effect of 4-week metoprolol treatment on clinical manifestations and cardiac hemodynamics in patients with ischemic heart disease].
Topics: Adult; Aged; Coronary Disease; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardi | 1990 |
Significance of coronary circulation in hypertensive heart disease for development and prevention of heart failure.
Topics: Adult; Animals; Cardiac Output, Low; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary | 1990 |
Is there a role for angiotensin-converting enzyme inhibitors in the treatment of chronic myocardial ischemia?
Topics: Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Coronary Disease; Delayed-A | 1990 |
Alprazolam withdrawal.
Topics: Alprazolam; Coronary Disease; Female; Humans; Metoprolol; Seizures; Substance Withdrawal Syndrome | 1990 |
Effects of metoprolol on rest and exercise cardiac function and plasma catecholamines in chronic congestive heart failure secondary to ischemic or idiopathic cardiomyopathy.
Topics: Aged; Cardiomyopathy, Dilated; Catecholamines; Chronic Disease; Coronary Disease; Epinephrine; Exerc | 1990 |
Thoracic epidural anesthesia improves global and regional left ventricular function during stress-induced myocardial ischemia in patients with coronary artery disease.
Topics: Aged; Analgesia, Epidural; Bupivacaine; Coronary Disease; Exercise Test; Female; Hemodynamics; Human | 1990 |
[Silent myocardial ischemia--risk for sports in coronary groups?].
Topics: Adult; Aged; Coronary Disease; Electrocardiography, Ambulatory; Exercise Test; Humans; Metoprolol; M | 1990 |
Effects of bisoprolol in relation to metoprolol and bufuralol on left ventricular hemodynamics at rest and during exercise in chronic ischemic heart disease.
Topics: Adrenergic beta-Antagonists; Bisoprolol; Coronary Circulation; Coronary Disease; Ethanolamines; Hear | 1986 |
[Use of cardioselective adrenergic beta 1 receptor blockader spesicor in patients with ischemic heart disease associated with bronchial asthma].
Topics: Anti-Arrhythmia Agents; Asthma; Atrial Fibrillation; Cardiac Complexes, Premature; Coronary Disease; | 1987 |
Cardiac anti-ischemic effect of metoprolol: role of beta-blockade within the ischemic region.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Cardiac Output; Cats; Coronary Disea | 1987 |
Effects of the serotonin-antagonist ketanserin on the function of ischaemic and normally perfused myocardium and modification by beta-1-blockade in anaesthetized normotensive dogs.
Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Heart; Heart Rate; Ketanserin; Metoprolol; Myocardi | 1989 |
Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors.
Topics: Adolescent; Adult; Cardiomyopathy, Dilated; Child; Child, Preschool; Coronary Disease; Heart Failure | 1989 |
Beta blockade to decrease silent myocardial ischemia during peripheral vascular surgery.
Topics: Adrenergic beta-Antagonists; Coronary Disease; Humans; Intraoperative Complications; Metoprolol | 1989 |
MAPHY and the two arms of HAPPHY.
Topics: Adrenergic beta-Antagonists; Arteriosclerosis; Benzothiadiazines; Coronary Disease; Diuretics; Human | 1989 |
[Drugs in secondary prevention of ischemic heart disease: achievements, problems and prospects].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Disease; Female; Humans; Isosorbide | 1989 |
Determination of light-chain myosin in pregnancy and under tocolysis.
Topics: Coronary Disease; Female; Hexoprenaline; Humans; Immunoenzyme Techniques; Metoprolol; Myosins; Pregn | 1989 |
Comparative effects of celiprolol and metoprolol on left ventricular volume in coronary artery disease.
Topics: Adrenergic beta-Antagonists; Celiprolol; Coronary Disease; Humans; Metoprolol; Propanolamines; Strok | 1985 |
The effect of beta blockers on cardiac neural discharge associated with coronary occlusion in the cat.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Cats; Coronary Disease; | 1987 |
Effect of beta-blockers on the relation between QT-interval and heart rate in exercise ECG.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; | 1987 |
Prevention of ventricular fibrillation by metoprolol in a pig model of acute myocardial ischaemia: absence of a major arrhythmogenic role for cyclic AMP.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Circu | 1986 |
Reduction in infarct size and enhanced recovery of systolic function after coronary thrombolysis with tissue-type plasminogen activator combined with beta-adrenergic blockade with metoprolol.
Topics: Animals; Coronary Disease; Coronary Thrombosis; Dogs; Drug Evaluation, Preclinical; Drug Therapy, Co | 1987 |
Serum potassium values in relation to the use of diuretics in patients with unstable angina pectoris.
Topics: Angina Pectoris; Angina, Unstable; Coronary Disease; Diuretics; Female; Humans; Hypokalemia; Male; M | 1988 |
Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Dogs; Female; Heart Conduct | 1987 |
Evaluation of the effect of metoprolol on energy metabolism in the ischaemic myocardium in relation to regional myocardial blood flow.
Topics: Acyl Coenzyme A; Adenosine Triphosphate; Animals; Blood Pressure; Coronary Circulation; Coronary Dis | 1987 |
[Effect of treatment with metoprolol on physical exertion tolerance and left ventricular function in patients with coronary disease].
Topics: Adult; Coronary Disease; Heart Ventricles; Humans; Male; Metoprolol; Middle Aged; Myocardial Contrac | 1986 |
On-line detection of reversible myocardial ischemic injury by measurement of myocardial electrical impedance.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Dogs; Electric Conductivity; Electrodes; Heart; I | 1987 |
Improvement by oral metoprolol of exercise-induced ischemic dysfunction in patients with coronary heart disease.
Topics: Administration, Oral; Adult; Angina Pectoris; Blood Pressure; Coronary Disease; Heart Rate; Humans; | 1986 |
Effects of molsidomine on regional contraction and global function of the left ventricle.
Topics: Adult; Coronary Disease; Exercise Test; Female; Heart Ventricles; Humans; Male; Metoprolol; Middle A | 1985 |
The effect of beta-adrenoceptor blockade and of thromboxane synthetase inhibition, alone and in combination, on arrhythmias resulting from myocardial ischemia.
Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Coronary Disease; Drug Administration Schedule; Drug | 1985 |
Effects of a combination of metoprolol and dazmegrel on myocardial infarct size in rats.
Topics: Animals; Coronary Disease; Drug Therapy, Combination; Imidazoles; Male; Metoprolol; Myocardial Infar | 1985 |