metoprolol has been researched along with Chemical and Drug Induced Liver Injury in 12 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| "Propranolol was without effect on blood glucose level." | 1.28 | Metoprolol and propranolol treatment in carbon tetrachloride-induced hepatic injury. ( Kulcsár, A; Kulcsár-Gergely, J, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Morgan, RE | 2 |
| Trauner, M | 1 |
| van Staden, CJ | 2 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 2 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 2 |
| Chen, M | 2 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 3 |
| Fang, H | 2 |
| Tong, W | 3 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Hansen, T | 1 |
| Fynne, L | 1 |
| Lin, K | 1 |
| Zhang, Q | 1 |
| Yang, S | 1 |
| Lin, Y | 1 |
| Wen, C | 1 |
| Zheng, Y | 1 |
| Meyer, MI | 1 |
| Kuhn, M | 1 |
| Bühler, H | 1 |
| Bertschinger, P | 1 |
| Kulcsár-Gergely, J | 1 |
| Kulcsár, A | 1 |
| Lennard, MS | 1 |
| Larrey, D | 1 |
| Henrion, J | 1 |
| Heller, F | 1 |
| Babany, G | 1 |
| Degott, C | 1 |
| Pessayre, D | 1 |
| Benhamou, JP | 1 |
1 review available for metoprolol and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
11 other studies available for metoprolol and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
[Jaundice and liver injury with cholestatic pattern after treatment with Metoprololsuccinat].
Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Female; Humans; J | 2017 |
Effects of suberoylanilide hydroxamic acid on rat cytochrome P450 enzyme activities.
Topics: Administration, Oral; Animals; Bupropion; Chemical and Drug Induced Liver Injury; Chromatography, Li | 2015 |
[Ticlopidine-induced cholestasis].
Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Chemical and Drug Induced Liver Injury; Cholestas | 1999 |
Metoprolol and propranolol treatment in carbon tetrachloride-induced hepatic injury.
Topics: Aminopyrine N-Demethylase; Animals; Bilirubin; Blood Glucose; Carbon Tetrachloride Poisoning; Chemic | 1992 |
Metoprolol-induced hepatitis: is the rate of oxidation related to drug-induced hepatotoxicity?
Topics: Chemical and Drug Induced Liver Injury; Humans; Liver; Metoprolol; Mixed Function Oxygenases; Oxidat | 1989 |
Metoprolol-induced hepatitis: rechallenge and drug oxidation phenotyping.
Topics: Chemical and Drug Induced Liver Injury; Debrisoquin; Female; Humans; Liver Function Tests; Metoprolo | 1988 |