Page last updated: 2024-10-31

metoprolol and Cerebrovascular Disorders

metoprolol has been researched along with Cerebrovascular Disorders in 9 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Cerebrovascular Disorders: A spectrum of pathological conditions of impaired blood flow in the brain. They can involve vessels (ARTERIES or VEINS) in the CEREBRUM, the CEREBELLUM, and the BRAIN STEM. Major categories include INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; BRAIN ISCHEMIA; CEREBRAL HEMORRHAGE; and others.

Research Excerpts

ExcerptRelevanceReference
"The effects of metoprolol treatment in patients surviving acute myocardial infarction have been investigated in a double-blind randomized study."9.05Long-term treatment with metoprolol after myocardial infarction: effect on 3 year mortality and morbidity. ( Erhardt, L; Lundman, T; Olsson, G; Rehnqvist, N; Sjögren, A, 1985)
"The question whether initial antihypertensive treatment with a beta-blocker prevents hypertensive complications better than initial treatment with a non-betablocker, mainly diuretic based treatment, has been studied in recent large-scale studies like the Medical Research Council (MRC) trial, the International Prospective Primary Prevention Study in Hypertension (IPPPSH), the Heart Attack Primary Prevention in Hypertension (HAPPHY) study and the Metoprolol Atherosclerosis Prevention in Hypertensives (MAPHY) study."5.06Beta-blockers and diuretics. The HAPPHY and MAPHY studies. ( Berglund, G, 1989)
"The effects of metoprolol treatment in patients surviving acute myocardial infarction have been investigated in a double-blind randomized study."5.05Long-term treatment with metoprolol after myocardial infarction: effect on 3 year mortality and morbidity. ( Erhardt, L; Lundman, T; Olsson, G; Rehnqvist, N; Sjögren, A, 1985)
"Clinical guidelines suggest that for patients with heart failure and concurrent chronic obstructive pulmonary disease (COPD), metoprolol/bisoprolol/nebivolol should be preferred over carvedilol."3.91Beta-blocker choice and exchangeability in patients with heart failure and chronic obstructive pulmonary disease: an Italian register-based cohort study. ( Andersen, M; Capuano, A; Jensen, MT; Kragholm, K; Mascolo, A; Pagliaro, C; Rafaniello, C; Rasmussen, DB; Rossi, F; Sessa, M; Sportiello, L; Tari, GM, 2019)
"3."1.29Improvement of cardiovascular effects of metoprolol by replacement of common salt with a potassium- and magnesium-enriched salt alternative. ( Karppanen, H; Laakso, J; Mervaala, EM; Vapaatalo, H, 1994)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's3 (33.33)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sessa, M1
Mascolo, A1
Rasmussen, DB1
Kragholm, K1
Jensen, MT1
Sportiello, L1
Rafaniello, C1
Tari, GM1
Pagliaro, C1
Andersen, M1
Rossi, F1
Capuano, A1
Bolduc, V1
Drouin, A1
Gillis, MA1
Duquette, N1
Thorin-Trescases, N1
Frayne-Robillard, I1
Des Rosiers, C1
Tardif, JC1
Thorin, E1
Naumann, UK1
Käser, L1
Vetter, W1
Mervaala, EM1
Laakso, J1
Vapaatalo, H1
Karppanen, H1
Tuomilehto, J2
Wikstrand, J2
Warnold, I2
Olsson, G3
Elmfeldt, D2
Berglund, G3
Jonas, S1
Rehnqvist, N1
Sjögren, A1
Erhardt, L1
Lundman, T1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Pharmacological Heart Rate Reduction on Visco-elastic Properties of the Arterial Wall (BRADYVASC)[NCT02584439]Phase 330 participants (Anticipated)Interventional2015-10-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

4 trials available for metoprolol and Cerebrovascular Disorders

ArticleYear
Coronary artery disease can be prevented by antihypertensive therapy: experiences from the MAPHY Study.
    Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 7

    Topics: Adult; Antihypertensive Agents; Benzothiadiazines; Cerebrovascular Disorders; Coronary Disease; Deat

1990
Beta-blockers and diuretics. The HAPPHY and MAPHY studies.
    Clinical and experimental hypertension. Part A, Theory and practice, 1989, Volume: 11, Issue:5-6

    Topics: Adrenergic beta-Antagonists; Arteriosclerosis; Benzothiadiazines; Cerebrovascular Disorders; Coronar

1989
Primary prevention with metoprolol in patients with hypertension. Mortality results from the MAPHY study.
    JAMA, 1988, Apr-01, Volume: 259, Issue:13

    Topics: Adult; Benzothiadiazines; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Diur

1988
Long-term treatment with metoprolol after myocardial infarction: effect on 3 year mortality and morbidity.
    Journal of the American College of Cardiology, 1985, Volume: 5, Issue:6

    Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Cerebrovascular Disorders; Clinical Trials as Topic; Co

1985

Other Studies

5 other studies available for metoprolol and Cerebrovascular Disorders

ArticleYear
Beta-blocker choice and exchangeability in patients with heart failure and chronic obstructive pulmonary disease: an Italian register-based cohort study.
    Scientific reports, 2019, 08-07, Volume: 9, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atrioventricular Block; Bisoprolol; Carvedilol

2019
Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Apolipoproteins B; Atherosclerosis; Benzazepines; Carotid Arteries;

2011
[Arterial hypertension 3: Hypertensive crisis: hypertensive emergency and hypertensive urgency].
    Praxis, 2006, Jun-21, Volume: 95, Issue:25-26

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Cereb

2006
Improvement of cardiovascular effects of metoprolol by replacement of common salt with a potassium- and magnesium-enriched salt alternative.
    British journal of pharmacology, 1994, Volume: 112, Issue:2

    Topics: Animals; Blood Pressure; Cerebrovascular Disorders; Eating; Electrolytes; Heart Rate; Hemodynamics;

1994
The Physician's Health Study. A neurologist's concern.
    Archives of neurology, 1990, Volume: 47, Issue:12

    Topics: Aspirin; Cerebrovascular Disorders; Cohort Studies; Follow-Up Studies; Humans; Male; Metoprolol; Myo

1990