Page last updated: 2024-10-31

metoprolol and Carotid Artery Diseases

metoprolol has been researched along with Carotid Artery Diseases in 9 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Carotid Artery Diseases: Pathological conditions involving the CAROTID ARTERIES, including the common, internal, and external carotid arteries. ATHEROSCLEROSIS and TRAUMA are relatively frequent causes of carotid artery pathology.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to test the hypothesis that the beta-blocker metoprolol succinate controlled release/extended release (CR/XL), when given to patients with hypercholesterolemia on concomitant lipid-lowering therapy, provides an additional antiatherosclerotic effect to that provided by the statins, measured as carotid intima-media thickness (IMT)."9.10Effect of controlled release/extended release metoprolol on carotid intima-media thickness in patients with hypercholesterolemia: a 3-year randomized study. ( Bondjers, G; Hulthe, J; Olofsson, SO; Schmidt, C; Wiklund, O; Wikstrand, J, 2002)
" The aim of this study was to test the hypothesis that the beta-blocker metoprolol succinate controlled release/extended release (CR/XL), when given to patients with hypercholesterolemia on concomitant lipid-lowering therapy, provides an additional antiatherosclerotic effect to that provided by the statins, measured as carotid intima-media thickness (IMT)."5.10Effect of controlled release/extended release metoprolol on carotid intima-media thickness in patients with hypercholesterolemia: a 3-year randomized study. ( Bondjers, G; Hulthe, J; Olofsson, SO; Schmidt, C; Wiklund, O; Wikstrand, J, 2002)
"In the Angina Prognosis Study in Stockholm (APSIS), 809 patients with stable angina pectoris were studied prospectively during double-blind treatment with verapamil or metoprolol."5.09Prognostic implications of intima-media thickness and plaques in the carotid and femoral arteries in patients with stable angina pectoris. ( Björkander, I; Eriksson, SV; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N, 2001)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's5 (55.56)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hallengren, E1
Almgren, P1
Rosvall, M1
Östling, G2
Persson, M1
Bergmann, A1
Struck, J1
Engström, G1
Hedblad, B2
Melander, O1
Shchukin, IuV1
Vachev, AN1
Surkova, EA1
Germanov, AV1
Golovin, EA1
D'iachkov, VA1
Gonçalves, I1
Wikstrand, J2
Berglund, G1
Nilsson, J1
Bolduc, V1
Drouin, A1
Gillis, MA1
Duquette, N1
Thorin-Trescases, N1
Frayne-Robillard, I1
Des Rosiers, C1
Tardif, JC1
Thorin, E1
Marfella, R1
Siniscalchi, M1
Nappo, F1
Gualdiero, P1
Esposito, K1
Sasso, FC1
Cacciapuoti, F1
Di Filippo, C1
Rossi, F1
D'Amico, M1
Giugliano, D1
Guan, YY1
Ye, BH1
Lu, HH1
Sheng, ZQ1
Zhang, L1
Hua, SM1
Tao, GH1
Yang, QC1
Held, C1
Hjemdahl, P1
Eriksson, SV1
Björkander, I1
Forslund, L1
Rehnqvist, N1
Wiklund, O1
Hulthe, J1
Schmidt, C1
Olofsson, SO1
Bondjers, G1
Spence, JD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Pharmacological Heart Rate Reduction on Visco-elastic Properties of the Arterial Wall (BRADYVASC)[NCT02584439]Phase 330 participants (Anticipated)Interventional2015-10-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

5 trials available for metoprolol and Carotid Artery Diseases

ArticleYear
Long-term treatment with low-dose metoprolol CR/XL is associated with increased plaque echogenicity: the Beta-blocker Cholesterol-lowering Asymptomatic Plaque Study (BCAPS).
    Atherosclerosis, 2011, Volume: 215, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Carotid Artery Diseases; Double-Blind Method; Fatty Acids, Monoun

2011
Regression of carotid atherosclerosis by control of morning blood pressure peak in newly diagnosed hypertensive patients.
    American journal of hypertension, 2005, Volume: 18, Issue:3

    Topics: Adult; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Carbazoles; Carotid Artery Di

2005
Prognostic implications of intima-media thickness and plaques in the carotid and femoral arteries in patients with stable angina pectoris.
    European heart journal, 2001, Volume: 22, Issue:1

    Topics: Aged; Angina Pectoris; Arteriosclerosis; Carotid Arteries; Carotid Artery Diseases; Coronary Artery

2001
Effect of controlled release/extended release metoprolol on carotid intima-media thickness in patients with hypercholesterolemia: a 3-year randomized study.
    Stroke, 2002, Volume: 33, Issue:2

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Carotid Artery Diseases; Cholesterol, LDL; Delayed-Acti

2002
Quantitative spectral analysis of carotid Doppler signal: evaluation as a method for measurement of drug effects.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1989, Volume: 12, Issue:2

    Topics: Adult; Arteriosclerosis; Carotid Arteries; Carotid Artery Diseases; Double-Blind Method; Heart Rate;

1989

Other Studies

4 other studies available for metoprolol and Carotid Artery Diseases

ArticleYear
Fasting levels of growth hormone are associated with carotid intima media thickness but are not affected by fluvastatin treatment.
    BMC cardiovascular disorders, 2017, 05-16, Volume: 17, Issue:1

    Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Aged, 80 and over; Biomarkers; Carotid Artery Diseases

2017
[The role of beta-adrenoblockers and If-inhibitor ivabradine in lowering of rate of development of cardiac complications after carotid endarterectomy].
    Kardiologiia, 2008, Volume: 48, Issue:5

    Topics: Adrenergic beta-Antagonists; Benzazepines; Carotid Artery Diseases; Drug Therapy, Combination; Endar

2008
Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Apolipoproteins B; Atherosclerosis; Benzazepines; Carotid Arteries;

2011
[Study of carvedilol on plaque stability in carotid atherosclerotic rabbits transfected by p53 gene].
    Zhonghua xin xue guan bing za zhi, 2007, Volume: 35, Issue:1

    Topics: Animal Feed; Animals; Apoptosis; Carbazoles; Carotid Artery Diseases; Carvedilol; Genes, p53; Humans

2007