metoprolol has been researched along with Cardiovascular Stroke in 497 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This meta-analysis aims to look at the impact of early intravenous Metoprolol in ST-segment elevation myocardial infarction (STEMI) before percutaneous coronary intervention (PCI) on infarct size, as measured by cardio magnetic resonance (CMR) and left ventricular ejection fraction." | 9.22 | Effect of early metoprolol before PCI in ST-segment elevation myocardial infarction on infarct size and left ventricular ejection fraction. A systematic review and meta-analysis of clinical trials. ( Aiash, H; Chébl, P; Elgabrty, N; Elshenawy, S; Gaber, H; Motawea, KR; Reyad, SM; Rozan, SS; Shoib, S; Singh, RB; Swed, S; Talat, NE; Wahsh, EA, 2022) |
| "We seek to examine the efficacy and safety of prereperfusion emergency medical services (EMS)-administered intravenous metoprolol in anterior ST-segment elevation myocardial infarction patients undergoing eventual primary angioplasty." | 9.20 | Efficacy and safety of out-of-hospital intravenous metoprolol administration in anterior ST-segment elevation acute myocardial infarction: insights from the METOCARD-CNIC trial. ( Barreiro, MV; Bravo, J; Chayán-Zas, L; Corral, E; Fernández-Friera, L; Fernández-Jiménez, R; Flores-Arias, J; Fuster, V; García-Álvarez, A; García-Lunar, I; García-Ruiz, JM; Huertas, P; Ibáñez, B; Mateos, A; Pizarro, G; Sánchez-Brunete, V, 2015) |
| "Previous metoprolol studies in myocardial infarction patients were performed with immediate-release (IR) metoprolol." | 9.19 | A pharmacokinetic and pharmacodynamic comparison of immediate-release metoprolol and extended-release metoprolol CR/XL in patients with suspected acute myocardial infarction: a randomized, open-label study. ( Aberg, J; Dellborg, M; Gullestad, L; Herlitz, J; Karlson, BW; Sugg, J, 2014) |
| "Early IV metoprolol during ST-segment elevation myocardial infarction (STEMI) has been shown to reduce infarct size when used in conjunction with primary percutaneous coronary intervention (pPCI)." | 9.19 | Long-term benefit of early pre-reperfusion metoprolol administration in patients with acute myocardial infarction: results from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction). ( Abejón, R; Albarrán, A; Barreiro, MV; Bastante, T; Cabrera, JA; de Miguel, A; Escalera, N; Escaned, J; Fernández-Friera, L; Fernández-Jiménez, R; Fernández-Ortiz, A; Fuster, V; García-Álvarez, A; García-Lunar, I; García-Prieto, J; García-Ruiz, JM; Goicolea, J; Guzman, G; Ibanez, B; Iñiguez, A; Jiménez, A; López-Melgar, B; Macaya, C; Martínez de Vega, V; Mateos, A; Mirelis, JG; Nieto, B; Pardillos, L; Parra-Fuertes, JJ; Pizarro, G; Pocock, S; Rodriguez, MD; Sánchez-Brunete, V; Sánchez-González, J; Zamorano, JL, 2014) |
| "Patients with Killip class II or less anterior ST-segment-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention within 6 hours of symptoms onset were randomized to receive intravenous metoprolol (n=131) or not (control, n=139) before reperfusion." | 9.17 | Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri ( Acebal, C; Albarrán, A; Arias, M; Bastante, T; Cabrera, JA; Casado, I; Cuellas, C; de la Torre-Hernández, JM; Escalera, N; Fernández-Campos, MJ; Fernández-Friera, L; Fernández-Jiménez, R; Fernández-Ortiz, A; Fernández-Vázquez, F; Fuster, V; García-Álvarez, A; García-Prieto, J; García-Rubira, JC; García-Ruiz, JM; Goicolea, J; Hernández-Antolín, R; Ibanez, B; Iglesias-Vázquez, JA; Iñiguez, A; Jiménez-Borreguero, J; López-Romero, P; Macaya, C; Mateos, A; Pérez de Prado, A; Pizarro, G; Pocock, S; Rodriguez, MD; Ruiz-Mateos, B; Sánchez-Brunete, V; Sanz, G; Sanz-Rosa, D; Valenciano, J, 2013) |
| " Changes in C-reactive protein (CRP) between days 1 and 5 after myocardial infarction were evaluated in 189 patients treated with simvastatin alone (S), beta blockers alone (B; propranolol or metoprolol), S + B, or neither of these 2 medications (N) in a prospective observational cohort." | 9.14 | Effect of beta blockers (metoprolol or propranolol) on effect of simvastatin in lowering C-reactive protein in acute myocardial infarction. ( Gurgel, A; Macedo, AC; Morato, TN; Munhoz, DB; Quinaglia e Silva, JC; Sever, P; Sposito, AC, 2009) |
| "To investigate individual metabolism-related determinants of metoprolol disposition and effects in patients receiving the drug as standard treatment for acute myocardial infarction (AMI)." | 9.13 | CYP2D6 is a major determinant of metoprolol disposition and effects in hospitalized Russian patients treated for acute myocardial infarction. ( Babak, S; Bergman, U; Bertilsson, L; Boldueva, S; Burbello, A; Goryachkina, K, 2008) |
| "To assess the effects of metoprolol on perioperative cardiovascular events in patients with risk or at high risk for coronary artery disease (CAD) who were to undergo non-cardiac surgery." | 9.13 | [Effects of metoprolol on perioperative cardiovascular events in patients with risk or at high risk for coronary artery disease undergoing non-cardiac surgery]. ( Wang, Q; Wang, S; Wu, XM; Yang, XY, 2008) |
| "To investigate the influence of paroxetine on metoprolol concentrations and its effect in patients treated for acute myocardial infarction (AMI) who are routinely given paroxetine as a co-treatment of depression." | 9.13 | Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI). ( Babak, S; Bergman, U; Bertilsson, L; Boldueva, S; Burbello, A; Goryachkina, K, 2008) |
| "In patients after myocardial infarction, carvedilol added to background therapy improved insulin resistance and lipid profile." | 9.12 | After myocardial infarction carvedilol improves insulin resistance compared to metoprolol. ( Altuntas, Y; Basat, O; Oztekin, E; Seber, S; Ucak, S, 2006) |
| "We explored whether vascular protection by carvedilol could contribute to its superior effects in the treatment of heart failure (HF) compared with metoprolol tartrate in the COMET (Carvedilol Or Metoprolol European Trial) study." | 9.12 | Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET. ( Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Metra, M; Moullet, C; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C, 2007) |
| "In patients with depressed < or =35% ejection fraction after acute myocardial infarction treatment with low doses of metoprolol, bisoprolol and cardvediolol did not reduce mortality rate in 24-month observation." | 9.12 | [Effect of low doses of metoprolol, bisoprolol and carvedilol on mortality in patients with left ventricular dysfunction after acute myocardial infarction]. ( Chizyński, K; Goch, JH; Maciejewski, M; Ptaszyński, P; Ruta, J, 2006) |
| "Carvedilol has previously been demonstrated to be beneficial in patients with acute myocardial infarction (AMI) and left ventricular (LV) dysfunction." | 9.12 | Randomized active-controlled study comparing effects of treatment with carvedilol versus metoprolol in patients with left ventricular dysfunction after acute myocardial infarction. ( Asanin, MR; Jelena, MM; Lasica, RM; Matic, MD; Mrdovic, IB; Ostojic, MC; Perunicic, JP; Savic, LZ; Vasiljevic, ZM, 2007) |
| " We determined the activities of copper-zinc superoxide dismutase (CuZnSOD), catalase, glutathione peroxidase and glutathione reductase in erythrocytes isolated from patients receiving different therapy (streptokinase alone or in combination with metoprolol or with carvedilol) for up to 168 hr after starting treatment for acute myocardial infarction." | 9.12 | Carvedilol increases copper-zinc superoxide dismutase activity in patients with acute myocardial infarction. ( Antonijević, NM; Blagojević, DP; Gojković-Bukarica, L; Jones, DR; Kastratović, DA; Lasica, RM; Marković, SZ; Matić, M; Mijalković, DN; Nikolić-Kokić, AL; Perunicić, JP; Spasić, MB; Stojiljkovic, MP; Vasiljević, ZM, 2007) |
| " To further explore the beneficial effects conferred by alpha-1-adrenoceptor blockade on ventricular repolarization dynamicity in the acute phase of myocardial infarction (AMI), we compared carvedilol with metoprolol in the setting of primary percutaneous coronary intervention (PCI)." | 9.11 | Carvedilol versus metoprolol in patients undergoing direct percutaneous coronary interventions for myocardial infarction: effects on QT dynamicity. ( Bode, F; Bonnemeier, H; Ortak, J; Richardt, G; Schmidt, J; Schunkert, H; Tölg, R; Wiegand, UK; Witt, M, 2005) |
| " To further explore the effects of additional alpha-1-adrenoceptor blockade on autonomic modulation in acute myocardial infarction (AMI), carvedilol was compared with metoprolol in the setting of primary percutaneous coronary interventions (PCI)." | 9.11 | Carvedilol versus metoprolol in the acute phase of myocardial infarction:. ( Bode, F; Bonnemeier, H; Ortak, J; Richardt, G; Schmidt, J; Schunkert, H; Tölg, R; Wiegand, UK; Witt, M, 2005) |
| "In a randomized double-blind design, 3029 patients with chronic congestive heart failure requiring diuretic therapy and with left ventricular dysfunction were randomized to treatment with carvedilol (n = 1511) or metoprolol tartrate (n = 1518) and titrated to target doses of 25 mg of carvedilol twice daily or 50 mg of metoprolol tartrate twice daily." | 9.11 | Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET. ( Cleland, JG; Di Lenarda, A; Hanrath, P; Komajda, M; Lutiger, B; Metra, M; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Skene, A; Swedberg, K; Torp-Pedersen, C, 2005) |
| "We performed a post-hoc subgroup analysis in the Metoprolol CR/XL Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF) with the aim of reporting on the heart rate (HR) response during the titration phase and clinical outcomes from the three-month follow-up visit to end of study in two dosage subgroups: one that had reached more than 100 mg of metoprolol CR/XL once daily (high-dose group; n = 1,202; mean 192 mg) and one that had reached 100 mg or less (low-dose group; n = 412; mean 76 mg)." | 9.10 | Dose of metoprolol CR/XL and clinical outcomes in patients with heart failure: analysis of the experience in metoprolol CR/XL randomized intervention trial in chronic heart failure (MERIT-HF). ( Fagerberg, B; Goldstein, S; Hjalmarson, A; Kjekshus, J; Waagstein, F; Wedel, H; Wikstrand, J, 2002) |
| "This was a prespecified subgroup analysis of a double-blind, randomized trial: the Metoprolol CR/XL Randomized Intervention Trial in Heart Failure (MERIT-HF)." | 9.10 | Metoprolol CR/XL in postmyocardial infarction patients with chronic heart failure: experiences from MERIT-HF. ( Czuriga, I; Ghali, JK; Herlitz, J; Hjalmarson, A; Jánosi, A; Klibaner, M; Wikstrand, J, 2003) |
| "To compare the analgesic effect of metoprolol and morphine in patients with chest pain due to suspected or definite acute myocardial infarction after initial treatment with intravenous metoprolol." | 9.09 | A comparison of metoprolol and morphine in the treatment of chest pain in patients with suspected acute myocardial infarction--the MEMO study. ( Abdon, NJ; Everts, B; Hedner, T; Herlitz, J; Karlson, B, 1999) |
| "The RIMA (Rimodellamento Infarto Miocardico Acuto) study was designed to assess the relative effects of angiotensin-converting enzyme (ACE) inhibition by captopril, beta-blocker therapy by metoprolol, and their combination in patients with a first acute myocardial infarction on: 1." | 9.09 | Effects of early treatment with captopril and metoprolol singly or together on six-month mortality and morbidity after acute myocardial infarction. Results of the RIMA (Rimodellamento Infarto Miocardico Acuto) study. The RIMA researchers. ( Bottero, G; Ceci, V; Coletta, C; Mazzuca, V; Pasquale, M; Putini, RL; Ricci, R; Rulli, F; Salustri, A; Seccareccia, F, 1999) |
| "The aim of this study was to describe the effect of intravenous metoprolol on the intensity of chest pain before hospital admission in patients with suspected acute myocardial infarction AMI)." | 9.09 | Effect of intravenous metoprolol before hospital admission on chest pain in suspected acute myocardial infarction. ( Brunnhage, C; Dellborg, M; Gardtman, M; Herlitz, J; Lindkvist, J; Waagstein, L, 1999) |
| " However, information on the effect of metoprolol XL on exercise capacity in relation to LV diastolic function in patients with mild to moderate LV systolic dysfunction after acute myocardial infarction is limited." | 9.09 | Improvement of exercise capacity and left ventricular diastolic function with metoprolol XL after acute myocardial infarction. ( Egstrup, K; Jensen, SE; Poulsen, SH, 2000) |
| "Assessing combined anti-platelet therapy in suspected acute myocardial infarction Aspirin has been shown to be effective in the emergency treatment of acute myocardial infarction." | 9.09 | Rationale, design and organization of the Second Chinese Cardiac Study (CCS-2): a randomized trial of clopidogrel plus aspirin, and of metoprolol, among patients with suspected acute myocardial infarction. Second Chinese Cardiac Study (CCS-2) Collaborativ ( , 2000) |
| "To evaluate whether xamoterol, a partial agonist, would improve exercise time more than metoprolol in patients with mild to moderate heart failure after a myocardial infarction." | 9.08 | Effects of beta receptor antagonists in patients with clinical evidence of heart failure after myocardial infarction: double blind comparison of metoprolol and xamoterol. ( Erhardt, L; Melcher, A; Persson, H; Rythe'n-Alder, E, 1995) |
| "The effect of quinapril or metoprolol on heart rate variability (HRV) indexes was studied in patients who had recovered from acute myocardial infarction." | 9.08 | Effect of quinapril or metoprolol on heart rate variability in post-myocardial infarction patients. ( Athyros, VG; Avramidis, MJ; Boudoulas, H; Kontopoulos, AG; Papadopoulos, GV; Papageorgiou, AA, 1996) |
| "We assessed the influence of metoprolol on heart rate variability in survivors of remote myocardial infarction." | 9.08 | Influence of metoprolol on heart rate variability in survivors of remote myocardial infarction. ( Hillis, LD; Keeley, EC; Landau, C; Lange, RA; Page, RL; Willard, JE, 1996) |
| "Two hundred and ten patients with clinical evidence of heart failure, developing after an acute myocardial infarction, were randomized to treatment with the beta 1-receptor antagonist metoprolol 50-100 mg b." | 9.08 | Effects of beta receptor antagonists on left ventricular function in patients with clinical evidence of heart failure after myocardial infarction. A double-blind comparison of metoprolol and xamoterol. Echocardiographic results from the Metoprolol and Xam ( Erhardt, L; Eriksson, SV; Persson, H, 1996) |
| "The influence of the beta-blocker metoprolol on the capacity either of low-dose dobutamine echocardiography or the recently introduced enoximone echocardiography to detect viable dysfunctioning myocardium after myocardial infarction was investigated." | 9.08 | Identification of viable myocardium early after acute myocardial infarction under beta-blockade by enoximone echocardiography. ( Giovannini, E; Milazzotto, F; Minardi, G; Natale, E; Tubaro, M; Vajola, SF; Wang, F, 1997) |
| "The aim of this study is to describe the impact of early treatment with metoprolol on prognosis during 1 year of follow-up in patients with suspected acute myocardial infarction (AMI) and indirect signs of congestive heart failure (CHF)." | 9.08 | Effect of metoprolol on the prognosis for patients with suspected acute myocardial infarction and indirect signs of congestive heart failure (a subgroup analysis of the Göteborg Metoprolol Trial). ( Herlitz, J; Hjalmarson, A; Lindqvist, J; Swedberg, K; Waagstein, F, 1997) |
| "A randomized trial was conducted to assess the efficacy of amiodarone versus metoprolol or no antiarrhythmic treatment to suppress asymptomatic ectopic activity and improve survival in patients who have had myocardial infarction with a left ventricular ejection fraction of 20 to 45% and > or = 3 ventricular premature complexes per hour (pairs or runs)." | 9.07 | Comparison of the effects of amiodarone versus metoprolol on the frequency of ventricular arrhythmias and on mortality after acute myocardial infarction. SSSD Investigators. Spanish Study on Sudden Death. ( Bayes de Luna, A; Cosin, J; Guindo, J; Marrugat, J; Navarro-López, F, 1993) |
| "The effects of 5 and 10 mg of amlodipine and of placebo were compared in 21 patients with stable angina pectoris and multivessel coronary artery disease." | 9.07 | Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle. ( Julínek, J; Meluzín, J; Novák, M; Simek, P; Spinarová, L; Stejfa, M; Toman, J; Zeman, K, 1992) |
| "To evaluate the influence of acute beta-blockade on the ability of predischarge exercise test data to predict long-term prognosis in patients admitted for suspected acute myocardial infarction, patients randomized at hospital admission to intravenous metoprolol or placebo were studied." | 9.07 | Prognostic importance of predischarge exercise capacity for long-term mortality and non-fatal myocardial infarction in patients admitted for suspected acute myocardial infarction and treated with metoprolol. ( Rønnevik, PK; von der Lippe, G, 1992) |
| "A total of 5778 patients with suspected acute myocardial infarction were randomized to early intravenous metoprolol followed by oral treatment for 15 d, or to placebo." | 9.07 | Long-term prognosis after early intervention with metoprolol in suspected acute myocardial infarction: experiences from the MIAMI Trial. The MIAMI Trial Research Group. ( , 1991) |
| "To ascertain whether predischarge arteriography is beneficial in patients with acute myocardial infarction treated with recombinant tissue-type plasminogen activator (rt-PA), heparin and aspirin, the outcome of 197 patients in the Thrombolysis in Myocardial Infarction (TIMI) IIA study assigned to conservative management and routine predischarge coronary arteriography (routine catheterization group) was compared with the outcome of 1,461 patients from the TIMI IIB study assigned to conservative management without routine coronary arteriography unless ischemia recurred spontaneously or on predischarge exercise testing (selective catheterization group)." | 9.07 | Selective versus routine predischarge coronary arteriography after therapy with recombinant tissue-type plasminogen activator, heparin and aspirin for acute myocardial infarction. TIMI II Investigators. ( Babb, JD; Baim, DS; Braunwald, E; Chesebro, JH; Frederick, M; Gore, JM; Passamani, ER; Roberts, R; Rogers, WJ; Williams, DO, 1991) |
| "The effects of metoprolol, administered in the early stages of acute myocardial infarction was studied in 126 patients." | 9.06 | The effects of metoprolol given early in acute myocardial infarction on ventricular arrhythmias. ( Littler, WA; Murray, DP; Murray, RG, 1986) |
| "One-hundred and ninety-seven consecutive patients admitted for suspected acute myocardial infarction were randomized to double-blind treatment with intravenous followed by oral metoprolol or matching placebo within 24 hours (mean 6." | 9.06 | Effect of metoprolol on early exercise-induced ST-segment changes and ventricular arrhythmias in patients with suspected acute myocardial infarction. ( Abrahamsen, AM; Gundersen, T; Knutsen, H; Rønnevik, PK; Woie, L, 1989) |
| "From two large scale studies in patients with suspected acute myocardial infarction we report the outcome in diabetics after treatment with either metoprolol or placebo." | 9.06 | Effects of metoprolol on mortality and late infarction in diabetics with suspected acute myocardial infarction. Retrospective data from two large studies. ( Herlitz, J; Hjalmarson, A; Malmberg, K; Rydén, L, 1989) |
| "The effect of metoprolol on indices of infarct size and left ventricular function was compared with that of placebo in a double-blind randomized trial in patients with definite or suspected acute myocardial infarction." | 9.06 | Effect of early metoprolol injection followed by oral dosage on CK-MB release, and myocardial function in suspected acute myocardial infarction. A double-blind controlled study. ( Halinen, MO; Kuikka, J; Länsimies, E; Miettinen, H; Palomäki, P; Penttilä, I; Pyörälä, K, 1989) |
| "The Lopressor Intervention Trial (LIT) was a double-blind, randomized, placebo-controlled, multicentre study designed to evaluate the effect of oral metoprolol on overall mortality in patients surviving a recent acute myocardial infarction." | 9.06 | The Lopressor Intervention Trial: multicentre study of metoprolol in survivors of acute myocardial infarction. Lopressor Intervention Trial Research Group. ( , 1987) |
| "In a subsample of 223 patients participating in a double-blind trial with metoprolol in suspected acute myocardial infarction, body temperature during the first 5 days in hospital was recorded." | 9.06 | Body temperature in acute myocardial infarction and its relation to early intervention with metoprolol. ( Bengtson, A; Herlitz, J; Hjalmarson, A; Wilhelmsen, L, 1988) |
| "In 1,395 patients in the age range 40-74 years participating in a double-blind trial with metoprolol in suspected acute myocardial infarction morbidity and quality of life were assessed during the first 5 years after randomization." | 9.06 | Morbidity and quality of life 5 years after early intervention with metoprolol in suspected acute myocardial infarction. ( Bengtson, A; Herlitz, J; Hjalmarson, A; Wiklund, I, 1988) |
| "A double blind randomised study of 154 patients with myocardial infarction assigned to metoprolol (100 mg twice daily) and 147 assigned to placebo compared the effects of treatment in relation to health state over three years." | 9.06 | Quality of life after myocardial infarction: effect of long term metoprolol on mortality and morbidity. ( Lubsen, J; Olsson, G; Rehnqvist, N; van Es, GA, 1986) |
| "The effect of therapy on exercise performance during a 3-year follow-up after acute myocardial infarction (AMI) was evaluated in a double-blind randomized comparison between 154 patients given metoprolol (100 mg twice daily) and 147 patients given placebo." | 9.06 | Influence of long-term metoprolol treatment on early and late exercise test performance after acute myocardial infarction. ( Freyschuss, U; Olsson, G; Rehnqvist, N; Zetterquist, S, 1988) |
| "This study reports the mortality over a 5-year-period determined a double-blind trial, which evaluated the effect of early intervention with metoprolol in suspected acute myocardial infarction." | 9.06 | Effects on mortality during five years after early intervention with metoprolol in suspected acute myocardial infarction. ( Herlitz, J; Hjalmarson, A; Rydén, L; Swedberg, K; Waagstein, F, 1988) |
| "Fifty three of the 5778 patients included in the MIAMI (Metoprolol in Acute Myocardial Infarction) trial were investigated with long-term ECG recordings in order to evaluate the effect of acute beta-blockade on premature ventricular complexes in and after acute myocardial infarction." | 9.06 | Metoprolol in acute myocardial infarction reduces ventricular arrhythmias both in the early stage and after the acute event. ( Ekman, AM; Erhardt, L; Olsson, G; Rehnqvist, N, 1987) |
| "To determine the effect of beta-adrenergic blockade on the submaximal stress test after acute myocardial infarction (AMI), 36 post-AMI patients performed their treadmill test on 2 separate days, with and without metoprolol, in a double-blind, placebo-controlled, crossover design study." | 9.06 | Effect of metoprolol on the submaximal stress test performed early after acute myocardial infarction. ( Ades, PA; Hanson, JS; LaMountain, J; Shapiro, SM; Thomas, JD, 1987) |
| "The mortality and morbidity were assessed during a 2-year follow-up in an acute intervention trial in suspected acute myocardial infarction with metoprolol (a selective beta 1-blocker)." | 9.06 | The influence of early intervention in acute myocardial infarction on long-term mortality and morbidity as assessed in the Göteborg metoprolol trial. ( Herlitz, J; Hjalmarson, A; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wilhelmsson, C, 1986) |
| "The Stockholm Metoprolol Trial is a prospective double-blind placebo-controlled postmyocardial infarction study of 301 patients treated with metoprolol, 100 mg b." | 9.06 | Reduction of nonfatal reinfarctions in patients with a history of hypertension by chronic postinfarction treatment with metoprolol. ( Olsson, G; Rehnqvist, N, 1986) |
| "The aim of this investigation was to study central haemodynamics in initially uncomplicated acute myocardial infarction (AMI) with respect to natural history, relation to enzyme estimated infarct size, mortality and effects of metoprolol." | 9.06 | Central haemodynamics in acute myocardial infarction. Natural history, relation to enzyme release and effects of metoprolol. ( Held, P, 1986) |
| "The central haemodynamic effects of metoprolol in patients with acute myocardial infarction and with heart rate less than or equal to 65 beats min-1 have been investigated in a randomized double-blind trial." | 9.06 | Central haemodynamic effects of metoprolol early in acute myocardial infarction. A placebo controlled randomized study of patients with low heart rate. ( Held, PH; Hjalmarson, A; Rydén, L; Swedberg, K, 1986) |
| "The effect of metoprolol on mortality was compared with that of placebo in a double blind randomised trial in patients with definite or suspected acute myocardial infarction." | 9.05 | Effect on mortality of metoprolol in acute myocardial infarction. A double-blind randomised trial. ( Elmfeldt, D; Herlitz, J; Hjalmarson, A; Holmberg, S; Málek, I; Nyberg, G; Rydén, L; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Waldenström, J; Wedel, H; Wilhelmsen, L; Wilhelmsson, C, 1981) |
| "In a double-blind randomized trial, 1,395 patients with suspected acute myocardial infarction (MI) were investigated to evaluate the possibility of limiting indirect signs of the size and severity of acute MI with the beta 1-selective adrenoceptor antagonist metoprolol." | 9.05 | Effect of metoprolol on indirect signs of the size and severity of acute myocardial infarction. ( Elmfeldt, D; Herlitz, J; Hjalmarson, A; Holmberg, S; Málek, I; Nyberg, G; Rydén, L; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Waldenström, J; Wedel, H; Wilhelmsen, L; Wilhelmsson, C, 1983) |
| "In the Göteborg Metoprolol Trial, 1395 patients with suspected acute myocardial infarction were, on admission, randomly allocated to double-blind treatment, 697 to placebo and 698 to metoprolol (15 mg i." | 9.05 | The Göteborg metoprolol trial. Effects on mortality and morbidity in acute myocardial infarction. ( Herlitz, J; Hjalmarson, A; Holmberg, S; Rydén, L; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Waldenström, J; Wedel, H; Wilhelmsen, L; Wilhelmsson, C, 1983) |
| "A total of 1395 patients aged 40 to 74 years were included in a double blind trial with the beta 1 selective blocker metoprolol in suspected acute myocardial infarction." | 9.05 | Effect of metoprolol on chest pain in acute myocardial infarction. ( Herlitz, J; Hjalmarson, A; Holmberg, S; Pennert, K; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wedel, H; Wilhelmsen, L, 1984) |
| "In a double blind study of metoprolol in the treatment of suspected acute myocardial infarction 698 patients (study group) received metoprolol and 697 a placebo (control group)." | 9.05 | Development of congestive heart failure after treatment with metoprolol in acute myocardial infarction. ( Herlitz, J; Hjalmarson, A; Holmberg, S; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wedel, H; Wilhelmsen, L; Wilhelmsson, C, 1984) |
| "In a double-blind trial, 30 patients with suspected acute myocardial infarction with onset of symptoms within the previous 24 h were randomized to treatment with 10 mg nifedipine/placebo orally 4 times a day during hospitalization." | 9.05 | Hemodynamic and clinical findings after combined therapy with metoprolol and nifedipine in acute myocardial infarction. ( Emanuelsson, H; Herlitz, J; Hjalmarson, A; Holmberg, S; Waagstein, F; Waldenström, A; Waldenström, J, 1984) |
| "The effect of metoprolol on chest pain was compared with that of placebo in all randomized patients." | 9.05 | Göteborg Metoprolol Trial: effects on chest pain. ( Herlitz, J; Hjalmarson, A; Holmberg, S; Richterova, A; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wennerblom, B; Wilhelmsson, C, 1984) |
| "During a double-blind trial in which patients with suspected myocardial infarction received metoprolol or placebo, we analyzed the occurrence of ventricular tachyarrhythmias." | 9.05 | A double-blind trial of metoprolol in acute myocardial infarction. Effects on ventricular tachyarrhythmias. ( Ariniego, R; Arnman, K; Herlitz, J; Hjalmarson, A; Holmberg, S; Reyes, C; Rydén, L; Smedgård, P; Svedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wedel, H; Wilhelmsson, C; Yamamoto, M, 1983) |
| "The effect of metoprolol on mortality and morbidity after 15 days, was compared with that of placebo in a double-blind randomised international trial (the MIAMI trial) in patients with definite or suspected acute myocardial infarction (AMI)." | 9.05 | Metoprolol in acute myocardial infarction (MIAMI). A randomised placebo-controlled international trial. The MIAMI Trial Research Group. ( , 1985) |
| "The effects of early intervention with metoprolol in patients with suspected or definite acute myocardial infarction (AMI) have been assessed in a randomized, double-blind, placebo-controlled international study." | 9.05 | Metoprolol in acute myocardial infarction. Patients and methods. The MIAMI Trial Research Group. ( , 1985) |
| "The effect of metoprolol on platelet aggregation was investigated in a group of postmyocardial infarction (MI) patients." | 9.05 | ADP-induced platelet aggregation and metoprolol treatment of myocardial infarction patients. A controlled study. ( Kutti, J; Swedberg, K; Vedin, A; Vilén, L, 1985) |
| "A double-blind trial with the beta 1-selective blocker metoprolol in suspected acute myocardial infarction and during 3 months' follow-up included 1395 patients, aged 40-74 years, 698 on metoprolol and 697 on placebo." | 9.05 | Tolerability to treatment with metoprolol in acute myocardial infarction in relation to age. ( Herlitz, J; Hjalmarson, A; Holmberg, S; Pennert, K; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Waldenström, J; Wedel, H, 1985) |
| "The effects of metoprolol treatment in patients surviving acute myocardial infarction have been investigated in a double-blind randomized study." | 9.05 | Long-term treatment with metoprolol after myocardial infarction: effect on 3 year mortality and morbidity. ( Erhardt, L; Lundman, T; Olsson, G; Rehnqvist, N; Sjögren, A, 1985) |
| "The effect of metoprolol on the development of an acute myocardial infarction (AMI) during days 0 to 3 and on late first and recurrent infarctions during days 4 to 15 has been investigated." | 9.05 | Metoprolol in acute myocardial infarction. Development of myocardial infarction. The MIAMI Trial Research Group. ( , 1985) |
| "The central hemodynamic effects of metoprolol in acute myocardial infarction have been studied in a multicenter, double-blind, randomized trial." | 9.05 | Hemodynamic effects of metoprolol in acute myocardial infarction. A randomized, placebo-controlled multicenter study. ( Corbeij, HM; Dunselman, P; Held, PH; Hjalmarson, A; Murray, D; Swedberg, K, 1985) |
| "1 Ten patients with acute myocardial infarction were infused dobutamine in increasing doses up to 15 microgram kg--1 min--1." | 9.04 | The use of dobutamine in myocardial infarction for reversal of the cardiodepressive effect of metoprolol. ( Hjalmarson, AC; Malek, I; Waagstein, F, 1978) |
| "Although carvedilol, a nonselective beta-blocker with alpha-adrenergic blocking and multiple ancillary activities, has been demonstrated to be superior to metoprolol in chronic heart failure, it remains unclear whether the superiority of carvedilol still exists in myocardial infarction (MI)." | 8.95 | Meta-Analysis Comparing Metoprolol and Carvedilol on Mortality Benefits in Patients With Acute Myocardial Infarction. ( Chen, Z; Gao, X; Ju, J; Li, J; Xiong, W; Xu, H; Zhang, H, 2017) |
| "Carvedilol is a beta-adrenergic antagonist with vasodilatory properties (alpha1-antagonism), which has been extensively evaluated in the treatment of patients with heart failure." | 8.84 | Carvedilol: use in chronic heart failure. ( Doughty, RN; White, HD, 2007) |
| "During the intervening years since metoprolol was first reviewed in the Journal (1977), it has become widely used in the treatment of mild to moderate hypertension and angina pectoris." | 8.77 | Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders. ( Benfield, P; Brogden, RN; Clissold, SP, 1986) |
| "To find the effects of dapagliflozin in combination with metoprolol sustained-release tablets on cardiac function and prognosis in acute myocardial infarction patients after PCI." | 8.12 | Effects of Dapagliflozin in Combination with Metoprolol Sustained-Release Tablets on Prognosis and Cardiac Function in Patients with Acute Myocardial Infarction after PCI. ( Liu, Z; Zhang, H, 2022) |
| "To explore the effect of metoprolol tartrate tablets and recombinant human natriuretic peptide B (NPPB) on sudden cardiac death and malignant arrhythmias in patients with acute myocardial infarction and patients with heart failure (AMI-HF)." | 8.02 | Effect of metoprolol tartrate tablets and recombinant human B-type natriuretic peptide on the sudden cardiac death and malignant arrhythmias in patients with acute myocardial infarction and heart failure. ( Lin, Y; Liu, C; Yao, L; Zhang, L, 2021) |
| "Metoprolol is regarded as a first-line medicine for the treatment of myocardial infarction (MI)." | 7.96 | Metoprolol protects against myocardial infarction by inhibiting miR-1 expression in rats. ( Li, Z; Qin, W; Xiao, D; Xu, C; Yang, H; Zhang, H; Zhang, L; Zhang, Y, 2020) |
| "Metoprolol (Met) is widely applied in the treatment of myocardial infarction and coronary heart disease in clinic." | 7.96 | Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia. ( Kou, J; Lai, Q; Li, F; Liu, Z; Wang, H; Yu, B; Yuan, G, 2020) |
| "Metoprolol exerts a disruptive action on neutrophil dynamics during exacerbated inflammation, resulting in an infarct-limiting effect not observed with atenolol or propranolol." | 7.96 | Metoprolol exerts a non-class effect against ischaemia-reperfusion injury by abrogating exacerbated inflammation. ( Clemente-Moragón, A; Fuster, V; García-Prieto, J; Gómez, M; Ibáñez, B; Lalama, DV; Martínez, F; Oliver, E; Sánchez-Cabo, F; Villena-Gutiérrez, R, 2020) |
| " We discuss the case of a patient with new-onset atrial fibrillation receiving metoprolol for rate control on a background of pseudoephedrine use for allergic rhinitis leading to acute myocardial infarction from multivessel coronary vasospasm." | 7.85 | Acute Myocardial Infarction from Coronary Vasospasm Precipitated by Pseudoephedrine and Metoprolol Use. ( Goldsweig, AM; Malm, BJ; Meoli, EM, 2017) |
| "Mice treated with sorafenib or vehicle for 3 weeks underwent induced myocardial infarction (MI) after 1 week of treatment." | 7.80 | Sorafenib cardiotoxicity increases mortality after myocardial infarction. ( Barbe, M; Berretta, RM; Dunn, J; Duran, JM; Force, T; Gao, E; Gross, P; Houser, SR; Husain, S; Kubo, H; Lal, H; Makarewich, CA; Sharp, TE; Starosta, T; Trappanese, D; Vagnozzi, RJ; Yu, D, 2014) |
| "In order to examine the reversibility of heart failure due to myocardial infarction (MI) by β-adrenoceptor blockade, 12 weeks infarcted rats were treated with or without metoprolol (50 mg/kg/day) for 8 weeks." | 7.79 | Reversal of cardiac dysfunction and subcellular alterations by metoprolol in heart failure due to myocardial infarction. ( Babick, A; Dhalla, NS; Elimban, V; Zieroth, S, 2013) |
| " Metoprolol can prevent sympathetic nerve remodeling after myocardial infarction (MI), but the underlying mechanism is unclear." | 7.79 | Metoprolol-mediated amelioration of sympathetic nerve sprouting after myocardial infarction. ( Cheng, WJ; Hu, HS; Liu, J; Suo, F; Wang, Y; Xuan, YL; Xue, M; Yan, SH, 2013) |
| "This study evaluated the effects of early treatment with β-adrenergic blocker metoprolol on ventricular remodeling and function after acute myocardial infarction (AMI) by using high frequency ultrasound." | 7.78 | High-frequency ultrasound evaluation of effects of early treatment with metoprolol on myocardial inflammatory cytokine expression in rats with acute myocardial infarction. ( Gao, Y; Huang, L; Wu, W; Yang, Y; Zhang, J, 2012) |
| " In this study, we characterised left ventricular thrombospondin-1 and -4 expression in rats treated with a beta-blocker metoprolol during the remodelling process in response to pressure overload and acute myocardial infarction." | 7.76 | Metoprolol treatment lowers thrombospondin-4 expression in rats with myocardial infarction and left ventricular hypertrophy. ( Aro, J; Leskinen, H; Luodonpää, M; Mustonen, E; Ruskoaho, H; Rysä, J; Vuolteenaho, O, 2010) |
| " More importantly, ruboxistaurin prevented death in wild-type mice throughout 10 weeks of pressure-overload stimulation, reduced ventricular dilation, enhanced ventricular performance, reduced fibrosis, and reduced pulmonary edema comparable to or better than metoprolol treatment." | 7.75 | Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach. ( Chen, X; Houser, SR; Kranias, EG; Leitges, M; Liu, Q; Lorenz, JN; Macdonnell, SM; Molkentin, JD, 2009) |
| "To investigate the effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction (MI)." | 7.74 | [Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction]. ( Chen, H; Guo, CY; Li, HW; Li, ZZ; Shen, LH; Sun, T; Tang, CS, 2008) |
| "Metoprolol reduces post-MI ventricular arrhythmias, partly by altering the neural remodeling process." | 7.74 | Effects of prolonged metoprolol treatment on neural remodeling and inducible ventricular arrhythmias after myocardial infarction in rabbits. ( Cheng, WJ; Hu, HS; Shi, CW; Wang, Q; Wang, XL; Xing, QC; Xue, M; Yan, SH, 2007) |
| " The aim of this study was to investigate the effects of metoprolol on sympathetic remodeling and electrical remodeling at the infarcted border zone (IBZ) after myocardial infarction (MI)." | 7.74 | Effects of metoprolol on sympathetic remodeling and electrical remodeling at infarcted border zone after myocardial infarction in rabbits. ( Huang, C; Jian, X; Jiang, H; Lu, Z; Yang, B; Yu, Y; Zhao, D, 2007) |
| " A patient suffering from coronary artery disease and taking metoprolol and aspirin was stung by wasps and developed cutaneous allergic signs including rash, urticaria and orbital oedema." | 7.74 | Hymenoptera sting-induced Kounis syndrome: effects of aspirin and beta-blocker administration. ( Ioannidis, TI; Karpeta, MZ; Kounis, GN; Kounis, NG; Mazarakis, A; Notaras, SP; Rallis, DG; Tsintoni, AC, 2007) |
| "Emergency physicians should bear in mind that AMI can accompany the presentation of metoprolol overdose in those with coronary artery disease." | 7.74 | Cardiovascular toxicity due to metoprolol poisoning in a patient with coronary artery disease. ( Bozkurt, S; Kaynak, F; Topacoglu, H; Unverir, P, 2007) |
| "The aim of study was to explore the effects of early beta-adrenergic blockade-metoprolol treatment on myocardial inflammatory cytokine expression and heart function in rats after acute myocardial infarction (AMI)." | 7.73 | [Effects of early treatment with metoprolol on myocardial inflammatory cytokine expression and heart function in rats with acute myocardial infarction]. ( Cheng, X; Ge, HX; Guo, ZQ; Li, B; Liao, YH; Liu, Y; Lu, BJ; Yang, YL; Zhang, JY; Zhang, L, 2005) |
| "To compare the beneficial effects of Atenolol and Metoprolol on cardiomyocyte apoptosis and related gene expressions after acute myocardial infarction (AMI) in rats." | 7.73 | [Effects of atenolol and metoprolol on cardiomyocyte apoptosis and related gene expression after acute myocardial infarction in rats]. ( Chen, JL; Chen, X; Chen, YF; Chen, ZJ; Gao, RL; Ruan, YM; Si, WX; Sun, RC; Tian, Y; Wang, QZ; Yang, YJ; Zhou, YW, 2006) |
| "Metoprolol succinate was given to 60 patients with class I-III heart failure and ejection fraction <45% after myocardial infarction." | 7.72 | [Effect of metoprolol CR/XL on remodeling of the heart and cardiac rhythm disturbances after myocardial infarction in patients with chronic heart failure]. ( Churganova, LIu; Gavril'eva, SA; Ivanov, GG; Poltavskaia, MG; Sheianov, MV; Shumilova, KM; Syrkin, AL, 2003) |
| "The Metoprolol CR/XL Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF), the Cardiac Insufficiency Bisoprolol Study II (CIBIS-II), and the Carvedilol Prospective Randomized Cumulative Survival Study (COPERNICUS) have all demonstrated highly significant positive effects on total mortality as well as total mortality plus all-cause hospitalization in patients with heart failure." | 7.72 | How should subgroup analyses affect clinical practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF). ( Deedwania, P; Fagerberg, B; Ghali, J; Goldstein, S; Gottlieb, S; Hjalmarson, A; Kjekshus, J; Waagstein, F; Wedel, H; Wikstrand, J, 2003) |
| "To compare the effects of carvedilol and metoprolol in preventing from left ventricular remodeling (LVRM) after acute myocardial infarction (AMI) in rats." | 7.71 | [Comparative effects of carvedilol and metoprolol in preventing from left ventricular remodeling after acute myocardial infarction in rats]. ( Chen, JL; Chen, ZJ; Gao, RL; Lu, SQ; Ruan, YM; Sun, RC; Tang, YD; Wang, PH; Yang, YJ; Zhang, P, 2001) |
| "The effects of chronic treatment with the beta-adrenoceptor antagonist metoprolol, the angiotensin converting enzyme inhibitor ramipril, their combination, or placebo on action potential configuration 6 weeks after myocardial infarction in rats were studied." | 7.70 | Effects of metoprolol and ramipril on action potentials after myocardial infarction in rats. ( Günther, J; Kamkin, A; Kiseleva, I; Scholz, H; Theres, H; Wagner, K, 2000) |
| "This analysis was carried out to clarify the capacity of metoprolol to prevent cardiac events in Japanese post-myocardial infarction patients during a follow-up period of 16." | 7.70 | Retrospective analysis showing less cardiac events in post-myocardial infarction patients treated with metoprolol. Secondary Prevention Group. ( Hayashi, T; Inoki, T; Ishikawa, K; Kanamasa, K; Katayama, K; Kimura, A; Kitayama, K; Miyataka, M; Takenaka, T; Yabushita, H, 2000) |
| "This study analyzed, with spectral techniques, the effects of atenolol or metoprolol on RR interval variability in 20 patients 4 weeks after the first uncomplicated myocardial infarction." | 7.69 | Effects of beta blockers (atenolol or metoprolol) on heart rate variability after acute myocardial infarction. ( La Rovere, MT; Lombardi, F; Malliani, A; Mortara, A; Sandrone, G; Torzillo, D, 1994) |
| "The effects of metoprolol on early infarct expansion after acute myocardial infarction were studied in rats (n = 54) that underwent either left coronary artery ligation (MI) or sham operation." | 7.69 | Effects of metoprolol on early infarct expansion after acute myocardial infarction. ( Cohn, PF; Jain, P; Lillis, O, 1994) |
| "Pain intensity and the plasma concentrations of metoprolol and its major metabolite alpha-hydroxymetoprolol as well as noradrenaline (NA), adrenaline (A) and neuropeptide Y (NPY) were determined in patients with pain due to definite or suspected acute myocardial infarction (AMI) after graded metoprolol infusion." | 7.69 | Effects and pharmacokinetics of high dose metoprolol on chest pain in patients with suspected or definite acute myocardial infarction. ( Abdon, NJ; Everts, B; Hedner, T; Herlitz, J; Karlson, BW, 1997) |
| "One hundred thirty-one patients presenting with acute myocardial infarction (AMI) a mean of 3 hours after the onset of symptoms were treated with oral aspirin and intravenous thrombolytic therapy followed by heparin." | 7.68 | Safety of combined intravenous beta-adrenergic blockade (atenolol or metoprolol) and thrombolytic therapy in acute myocardial infarction. ( Commerford, PJ; Gordon, GD; Green, BK; Horak, AR; Millar, RN, 1992) |
| "During the initial hospitalization, ventricular fibrillation (VF) developed in 6 metoprolol-treated patients (0." | 7.67 | Göteborg Metoprolol Trial: effects on arrhythmias. ( Edvardsson, N; Herlitz, J; Hjalmarson, A; Holmberg, S; Rydén, L; Swedberg, K; Waagstein, F; Waldenström, A, 1984) |
| "The acute effects of intravenous metoprolol were evaluated in 30 patients with myocardial infarction by means of serial hemodynamic and radionuclide measurements of left ventricular function." | 7.67 | Hemodynamic effects of intravenous metoprolol in acute myocardial infarction: the role of anatomic subsets in predicting patient response. ( Breisblatt, WM; Burns, MJ; Spaccavento, LJ; Waldo, DA, 1988) |
| "To determine the effects of intravenous metoprolol on left ventricular (LV) function in acute myocardial infarction (AMI), 16 patients were studied within 48 hours of Q-wave AMI (mean ejection fraction 47 +/- 6%, mean pulmonary artery wedge pressure 22 +/- 6 mm Hg) with high fidelity pressure and biplane cineventriculography before and after intravenous metoprolol (dose 12 +/- 4 mg)." | 7.67 | Effect of intravenous metoprolol on left ventricular performance in Q-wave acute myocardial infarction. ( Dell'Italia, LJ; Walsh, RA, 1989) |
| "Chronic treatment with metoprolol of postmyocardial infarction patients did not influence the response to an intravenous glucose tolerance test." | 7.67 | Effects of chronic metoprolol treatment on glucose tolerance after myocardial infarction. ( Olsson, G; Rehnqvist, N, 1987) |
| " and oral dosage regimen of metoprolol early in acute myocardial infarction has been evaluated." | 7.67 | Metoprolol in acute myocardial infarction. A pharmacokinetic and pharmacodynamic study. ( Held, PH; Regårdh, CG, 1986) |
| " Its short-term antiarrhythmic effects were compared with those of metoprolol, which has neither short-term class III nor membrane-stabilizing action, on reentrant ventricular arrhythmias produced by programmed stimulation in 17 conscious dogs 3 to 8 days after myocardial infarction." | 7.66 | Action of sotalol on potential reentrant pathways and ventricular tachyarrhythmias in conscious dogs in the late postmyocardial infarction phase. ( Brachmann, J; Cobbe, SM; Hoffman, E; Kübler, W; Ritzenhoff, A; Senges, J, 1983) |
| "Metoprolol, a cardioselective beta-receptor blocker, was administered to 12 patients three to ten hours after sustaining a transmural myocardial infarction, and the effect of the drug (10 mg i." | 7.66 | [Treatment of acute myocardial infarction with metoprolol (author's transl)]. ( Delius, W; Klein, G; Sack, D; Wirtzfeld, A, 1978) |
| "Metoprolol was administered as an initial dose of 15 mg intravenously, following 6-8 hours 100 mg/d orally." | 6.70 | [Effects of metoprolol on the signal averaged electrocardiogram and QT dispersion in acute myocardial infarction]. ( Akilli, A; Ceyhan, C; Onbaşili, OA; Tekten, T; Türkoğlu, C, 2002) |
| "In metoprolol treated patients in whom the arrhythmia frequency was reduced by greater than 75% after three days of treatment, mortality was lower as compared to those metoprolol treated patients who did not show this treatment response (3% vs 28%, P = 0." | 6.66 | Evaluation of antiarrhythmic effect of metoprolol treatment after acute myocardial infarction: relationship between treatment responses and survival during a 3-year follow-up. ( Olsson, G; Rehnqvist, N, 1986) |
| "Metoprolol 15 mg was given IV followed by a total daily dose of 200 mg/day." | 6.65 | Acute intervention with metoprolol in myocardial infarction. ( Hjalmarson, A, 1981) |
| "Metoprolol is a beta 1-selective adrenoceptor antagonist that is widely used in several indications." | 6.39 | Metoprolol: a pharmacoeconomic and quality-of-life evaluation of its use in hypertension, post-myocardial infarction and dilated cardiomyopathy. ( Benfield, P; Peters, DH, 1994) |
| "In the last year, two large randomized controlled trials of metoprolol (MIAMI, almost 6,000 patients) and atenolol (ISIS 1, over 16,000 patients) given intravenously within 12 hours of the onset of acute myocardial infarction reduced mortality by about 15% in low-risk subjects." | 6.15 | Use of beta adrenoceptor blockade during and after acute myocardial infarction. ( Sleight, P, 1986) |
| "Whereas prior experiments in juvenile pigs had reported infarct size reduction by intravenous metoprolol early during myocardial ischaemia, two major clinical trials in patients with reperfused acute myocardial infarction were equivocal." | 5.69 | No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs. ( Heusch, G; Kleinbongard, P; Lieder, HR; Skyschally, A, 2023) |
| " Beta-blocker dosage groups were >0% to12." | 5.62 | Comparison of Metoprolol Versus Carvedilol After Acute Myocardial Infarction. ( Fintel, DJ; Germano, JJ; Goldberger, JJ; Shani, J; Subacius, H; Zaatari, G, 2021) |
| " At follow-up, metoprolol dosage after up-titration, metoprolol steady-state trough plasma concentrations, hemodynamic parameters, potential metoprolol-induced adverse drug reactions and number of visits to the GP were measured." | 5.56 | Impact of genotype-predicted CYP2D6 metabolism on clinical effects and tolerability of metoprolol in patients after myocardial infarction - a prospective observational study. ( Anstensrud, AK; Fosshaug, LE; Haug, HJ; Molden, E; Muriq, H; Qazi, R; Spigset, O; Øie, E, 2020) |
| "Metoprolol was given 20 mg/kg/day for 5 weeks after MI surgery." | 5.48 | Comparison between renal denervation and metoprolol on the susceptibility of ventricular arrhythmias in rats with myocardial infarction. ( Chen, C; Geng, J; Huo, J; Jiang, W; Jiang, Z; Lu, D; Shan, Q; Xu, H, 2018) |
| "We assessed myocardial infarction in the transmural and lateral dimensions in a cohort of 220 acute ST-segment elevation myocardial infarction (STEMI) patients from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction)." | 5.41 | Coexistence of transmural and lateral wavefront progression of myocardial infarction in the human heart. ( Fernández-Friera, L; Fernández-Jiménez, R; Fuster, V; García-Álvarez, A; García-Ruiz, JM; Ibáñez, B; Jiménez-Blanco, M; Lobo-González, M; Lorca, R; Pizarro, G; Rossello, X, 2021) |
| "Metoprolol can inhibit the expression of c-fos and has a positive therapeutic effect on rats after AMI; the involvement effect of metoprolol on myocardial infarction might be correlated with its effect on the inhibition of c-fos." | 5.39 | The effect of c-fos on acute myocardial infarction and the significance of metoprolol intervention in a rat model. ( Ge, J; Goldstein, S; He, B; Li, Y; Ruiz, G; Zhang, M; Zhang, S, 2013) |
| "Metoprolol treatment for 2 weeks improved LV systolic function." | 5.35 | Divergent effects of losartan and metoprolol on cardiac remodeling, c-kit+ cells, proliferation and apoptosis in the left ventricle after myocardial infarction. ( Kerkelä, R; Kubin, AM; Leskinen, H; Pieviläinen, O; Ruskoaho, H; Serpi, R; Soini, Y; Tenhunen, O; Tolonen, AM; Vaskivuo, T, 2009) |
| "Treatment with growth hormone alone or in combination with metoprolol preserved left ventricular function after MI." | 5.31 | Growth hormone alone or combined with metoprolol preserves cardiac function after myocardial infarction in rats. ( Bengtsson, BA; Bergh, CH; Bollano, E; Caidahl, K; Isgaard, J; Kjellström, C; Kujacic, V; Omerovic, E; Waagstein, F, 2001) |
| "The arrhythmias were prevented by higher doses of the calcium antagonist verapamil which, however, decreased the survival times." | 5.26 | Comparative investigation of the effects of metoprolol, propranolol, practolol, and verapamil in the acute phase of experimental myocardial infarction. ( Bernauer, W, 1982) |
| "This meta-analysis aims to look at the impact of early intravenous Metoprolol in ST-segment elevation myocardial infarction (STEMI) before percutaneous coronary intervention (PCI) on infarct size, as measured by cardio magnetic resonance (CMR) and left ventricular ejection fraction." | 5.22 | Effect of early metoprolol before PCI in ST-segment elevation myocardial infarction on infarct size and left ventricular ejection fraction. A systematic review and meta-analysis of clinical trials. ( Aiash, H; Chébl, P; Elgabrty, N; Elshenawy, S; Gaber, H; Motawea, KR; Reyad, SM; Rozan, SS; Shoib, S; Singh, RB; Swed, S; Talat, NE; Wahsh, EA, 2022) |
| "We seek to examine the efficacy and safety of prereperfusion emergency medical services (EMS)-administered intravenous metoprolol in anterior ST-segment elevation myocardial infarction patients undergoing eventual primary angioplasty." | 5.20 | Efficacy and safety of out-of-hospital intravenous metoprolol administration in anterior ST-segment elevation acute myocardial infarction: insights from the METOCARD-CNIC trial. ( Barreiro, MV; Bravo, J; Chayán-Zas, L; Corral, E; Fernández-Friera, L; Fernández-Jiménez, R; Flores-Arias, J; Fuster, V; García-Álvarez, A; García-Lunar, I; García-Ruiz, JM; Huertas, P; Ibáñez, B; Mateos, A; Pizarro, G; Sánchez-Brunete, V, 2015) |
| "Previous metoprolol studies in myocardial infarction patients were performed with immediate-release (IR) metoprolol." | 5.19 | A pharmacokinetic and pharmacodynamic comparison of immediate-release metoprolol and extended-release metoprolol CR/XL in patients with suspected acute myocardial infarction: a randomized, open-label study. ( Aberg, J; Dellborg, M; Gullestad, L; Herlitz, J; Karlson, BW; Sugg, J, 2014) |
| "Early IV metoprolol during ST-segment elevation myocardial infarction (STEMI) has been shown to reduce infarct size when used in conjunction with primary percutaneous coronary intervention (pPCI)." | 5.19 | Long-term benefit of early pre-reperfusion metoprolol administration in patients with acute myocardial infarction: results from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction). ( Abejón, R; Albarrán, A; Barreiro, MV; Bastante, T; Cabrera, JA; de Miguel, A; Escalera, N; Escaned, J; Fernández-Friera, L; Fernández-Jiménez, R; Fernández-Ortiz, A; Fuster, V; García-Álvarez, A; García-Lunar, I; García-Prieto, J; García-Ruiz, JM; Goicolea, J; Guzman, G; Ibanez, B; Iñiguez, A; Jiménez, A; López-Melgar, B; Macaya, C; Martínez de Vega, V; Mateos, A; Mirelis, JG; Nieto, B; Pardillos, L; Parra-Fuertes, JJ; Pizarro, G; Pocock, S; Rodriguez, MD; Sánchez-Brunete, V; Sánchez-González, J; Zamorano, JL, 2014) |
| "Patients with Killip class II or less anterior ST-segment-elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention within 6 hours of symptoms onset were randomized to receive intravenous metoprolol (n=131) or not (control, n=139) before reperfusion." | 5.17 | Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri ( Acebal, C; Albarrán, A; Arias, M; Bastante, T; Cabrera, JA; Casado, I; Cuellas, C; de la Torre-Hernández, JM; Escalera, N; Fernández-Campos, MJ; Fernández-Friera, L; Fernández-Jiménez, R; Fernández-Ortiz, A; Fernández-Vázquez, F; Fuster, V; García-Álvarez, A; García-Prieto, J; García-Rubira, JC; García-Ruiz, JM; Goicolea, J; Hernández-Antolín, R; Ibanez, B; Iglesias-Vázquez, JA; Iñiguez, A; Jiménez-Borreguero, J; López-Romero, P; Macaya, C; Mateos, A; Pérez de Prado, A; Pizarro, G; Pocock, S; Rodriguez, MD; Ruiz-Mateos, B; Sánchez-Brunete, V; Sanz, G; Sanz-Rosa, D; Valenciano, J, 2013) |
| " Changes in C-reactive protein (CRP) between days 1 and 5 after myocardial infarction were evaluated in 189 patients treated with simvastatin alone (S), beta blockers alone (B; propranolol or metoprolol), S + B, or neither of these 2 medications (N) in a prospective observational cohort." | 5.14 | Effect of beta blockers (metoprolol or propranolol) on effect of simvastatin in lowering C-reactive protein in acute myocardial infarction. ( Gurgel, A; Macedo, AC; Morato, TN; Munhoz, DB; Quinaglia e Silva, JC; Sever, P; Sposito, AC, 2009) |
| "To investigate individual metabolism-related determinants of metoprolol disposition and effects in patients receiving the drug as standard treatment for acute myocardial infarction (AMI)." | 5.13 | CYP2D6 is a major determinant of metoprolol disposition and effects in hospitalized Russian patients treated for acute myocardial infarction. ( Babak, S; Bergman, U; Bertilsson, L; Boldueva, S; Burbello, A; Goryachkina, K, 2008) |
| "To assess the effects of metoprolol on perioperative cardiovascular events in patients with risk or at high risk for coronary artery disease (CAD) who were to undergo non-cardiac surgery." | 5.13 | [Effects of metoprolol on perioperative cardiovascular events in patients with risk or at high risk for coronary artery disease undergoing non-cardiac surgery]. ( Wang, Q; Wang, S; Wu, XM; Yang, XY, 2008) |
| "To investigate the influence of paroxetine on metoprolol concentrations and its effect in patients treated for acute myocardial infarction (AMI) who are routinely given paroxetine as a co-treatment of depression." | 5.13 | Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI). ( Babak, S; Bergman, U; Bertilsson, L; Boldueva, S; Burbello, A; Goryachkina, K, 2008) |
| "In patients after myocardial infarction, carvedilol added to background therapy improved insulin resistance and lipid profile." | 5.12 | After myocardial infarction carvedilol improves insulin resistance compared to metoprolol. ( Altuntas, Y; Basat, O; Oztekin, E; Seber, S; Ucak, S, 2006) |
| "We explored whether vascular protection by carvedilol could contribute to its superior effects in the treatment of heart failure (HF) compared with metoprolol tartrate in the COMET (Carvedilol Or Metoprolol European Trial) study." | 5.12 | Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET. ( Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Metra, M; Moullet, C; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C, 2007) |
| "In patients with depressed < or =35% ejection fraction after acute myocardial infarction treatment with low doses of metoprolol, bisoprolol and cardvediolol did not reduce mortality rate in 24-month observation." | 5.12 | [Effect of low doses of metoprolol, bisoprolol and carvedilol on mortality in patients with left ventricular dysfunction after acute myocardial infarction]. ( Chizyński, K; Goch, JH; Maciejewski, M; Ptaszyński, P; Ruta, J, 2006) |
| "Carvedilol has previously been demonstrated to be beneficial in patients with acute myocardial infarction (AMI) and left ventricular (LV) dysfunction." | 5.12 | Randomized active-controlled study comparing effects of treatment with carvedilol versus metoprolol in patients with left ventricular dysfunction after acute myocardial infarction. ( Asanin, MR; Jelena, MM; Lasica, RM; Matic, MD; Mrdovic, IB; Ostojic, MC; Perunicic, JP; Savic, LZ; Vasiljevic, ZM, 2007) |
| " We determined the activities of copper-zinc superoxide dismutase (CuZnSOD), catalase, glutathione peroxidase and glutathione reductase in erythrocytes isolated from patients receiving different therapy (streptokinase alone or in combination with metoprolol or with carvedilol) for up to 168 hr after starting treatment for acute myocardial infarction." | 5.12 | Carvedilol increases copper-zinc superoxide dismutase activity in patients with acute myocardial infarction. ( Antonijević, NM; Blagojević, DP; Gojković-Bukarica, L; Jones, DR; Kastratović, DA; Lasica, RM; Marković, SZ; Matić, M; Mijalković, DN; Nikolić-Kokić, AL; Perunicić, JP; Spasić, MB; Stojiljkovic, MP; Vasiljević, ZM, 2007) |
| "The purpose of the study was to evaluate the influence of metoprolol succinate and carvedilol on the physical ability (FA) of patients with chronic heart failure (CHF) of different etiologies." | 5.12 | [The effects of beta-adrenoblocker therapy on the physical working capacity of patients with chronic heart failure of various origin]. ( Andreev, DA; Kalashnikov, VIu; Poltavskaia, MG; Sarkisova, EA; Svet, AV; Syrkin, AL, 2007) |
| " To further explore the beneficial effects conferred by alpha-1-adrenoceptor blockade on ventricular repolarization dynamicity in the acute phase of myocardial infarction (AMI), we compared carvedilol with metoprolol in the setting of primary percutaneous coronary intervention (PCI)." | 5.11 | Carvedilol versus metoprolol in patients undergoing direct percutaneous coronary interventions for myocardial infarction: effects on QT dynamicity. ( Bode, F; Bonnemeier, H; Ortak, J; Richardt, G; Schmidt, J; Schunkert, H; Tölg, R; Wiegand, UK; Witt, M, 2005) |
| " To further explore the effects of additional alpha-1-adrenoceptor blockade on autonomic modulation in acute myocardial infarction (AMI), carvedilol was compared with metoprolol in the setting of primary percutaneous coronary interventions (PCI)." | 5.11 | Carvedilol versus metoprolol in the acute phase of myocardial infarction:. ( Bode, F; Bonnemeier, H; Ortak, J; Richardt, G; Schmidt, J; Schunkert, H; Tölg, R; Wiegand, UK; Witt, M, 2005) |
| "In a randomized double-blind design, 3029 patients with chronic congestive heart failure requiring diuretic therapy and with left ventricular dysfunction were randomized to treatment with carvedilol (n = 1511) or metoprolol tartrate (n = 1518) and titrated to target doses of 25 mg of carvedilol twice daily or 50 mg of metoprolol tartrate twice daily." | 5.11 | Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET. ( Cleland, JG; Di Lenarda, A; Hanrath, P; Komajda, M; Lutiger, B; Metra, M; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Skene, A; Swedberg, K; Torp-Pedersen, C, 2005) |
| "We performed a post-hoc subgroup analysis in the Metoprolol CR/XL Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF) with the aim of reporting on the heart rate (HR) response during the titration phase and clinical outcomes from the three-month follow-up visit to end of study in two dosage subgroups: one that had reached more than 100 mg of metoprolol CR/XL once daily (high-dose group; n = 1,202; mean 192 mg) and one that had reached 100 mg or less (low-dose group; n = 412; mean 76 mg)." | 5.10 | Dose of metoprolol CR/XL and clinical outcomes in patients with heart failure: analysis of the experience in metoprolol CR/XL randomized intervention trial in chronic heart failure (MERIT-HF). ( Fagerberg, B; Goldstein, S; Hjalmarson, A; Kjekshus, J; Waagstein, F; Wedel, H; Wikstrand, J, 2002) |
| "This was a prespecified subgroup analysis of a double-blind, randomized trial: the Metoprolol CR/XL Randomized Intervention Trial in Heart Failure (MERIT-HF)." | 5.10 | Metoprolol CR/XL in postmyocardial infarction patients with chronic heart failure: experiences from MERIT-HF. ( Czuriga, I; Ghali, JK; Herlitz, J; Hjalmarson, A; Jánosi, A; Klibaner, M; Wikstrand, J, 2003) |
| "To compare the analgesic effect of metoprolol and morphine in patients with chest pain due to suspected or definite acute myocardial infarction after initial treatment with intravenous metoprolol." | 5.09 | A comparison of metoprolol and morphine in the treatment of chest pain in patients with suspected acute myocardial infarction--the MEMO study. ( Abdon, NJ; Everts, B; Hedner, T; Herlitz, J; Karlson, B, 1999) |
| "The RIMA (Rimodellamento Infarto Miocardico Acuto) study was designed to assess the relative effects of angiotensin-converting enzyme (ACE) inhibition by captopril, beta-blocker therapy by metoprolol, and their combination in patients with a first acute myocardial infarction on: 1." | 5.09 | Effects of early treatment with captopril and metoprolol singly or together on six-month mortality and morbidity after acute myocardial infarction. Results of the RIMA (Rimodellamento Infarto Miocardico Acuto) study. The RIMA researchers. ( Bottero, G; Ceci, V; Coletta, C; Mazzuca, V; Pasquale, M; Putini, RL; Ricci, R; Rulli, F; Salustri, A; Seccareccia, F, 1999) |
| "The aim of this study was to describe the effect of intravenous metoprolol on the intensity of chest pain before hospital admission in patients with suspected acute myocardial infarction AMI)." | 5.09 | Effect of intravenous metoprolol before hospital admission on chest pain in suspected acute myocardial infarction. ( Brunnhage, C; Dellborg, M; Gardtman, M; Herlitz, J; Lindkvist, J; Waagstein, L, 1999) |
| " However, information on the effect of metoprolol XL on exercise capacity in relation to LV diastolic function in patients with mild to moderate LV systolic dysfunction after acute myocardial infarction is limited." | 5.09 | Improvement of exercise capacity and left ventricular diastolic function with metoprolol XL after acute myocardial infarction. ( Egstrup, K; Jensen, SE; Poulsen, SH, 2000) |
| "In the Angina Prognosis Study in Stockholm (APSIS), 809 patients with stable angina pectoris were studied prospectively during double-blind treatment with verapamil or metoprolol." | 5.09 | Prognostic implications of intima-media thickness and plaques in the carotid and femoral arteries in patients with stable angina pectoris. ( Björkander, I; Eriksson, SV; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N, 2001) |
| "Assessing combined anti-platelet therapy in suspected acute myocardial infarction Aspirin has been shown to be effective in the emergency treatment of acute myocardial infarction." | 5.09 | Rationale, design and organization of the Second Chinese Cardiac Study (CCS-2): a randomized trial of clopidogrel plus aspirin, and of metoprolol, among patients with suspected acute myocardial infarction. Second Chinese Cardiac Study (CCS-2) Collaborativ ( , 2000) |
| "This study was designed to describe the 5-year mortality rate in relation to the dose of metoprolol prescribed at hospital discharge after hospitalisation for acute myocardial infarction (AMI)." | 5.09 | Long-term mortality after acute myocardial infarction in relation to prescribed dosages of a beta-blocker at hospital discharge. ( Dellborg, M; Herlitz, J; Karlson, BW; Lindqvist, J; Wedel, H, 2000) |
| "To evaluate whether xamoterol, a partial agonist, would improve exercise time more than metoprolol in patients with mild to moderate heart failure after a myocardial infarction." | 5.08 | Effects of beta receptor antagonists in patients with clinical evidence of heart failure after myocardial infarction: double blind comparison of metoprolol and xamoterol. ( Erhardt, L; Melcher, A; Persson, H; Rythe'n-Alder, E, 1995) |
| "The effect of quinapril or metoprolol on heart rate variability (HRV) indexes was studied in patients who had recovered from acute myocardial infarction." | 5.08 | Effect of quinapril or metoprolol on heart rate variability in post-myocardial infarction patients. ( Athyros, VG; Avramidis, MJ; Boudoulas, H; Kontopoulos, AG; Papadopoulos, GV; Papageorgiou, AA, 1996) |
| "We assessed the influence of metoprolol on heart rate variability in survivors of remote myocardial infarction." | 5.08 | Influence of metoprolol on heart rate variability in survivors of remote myocardial infarction. ( Hillis, LD; Keeley, EC; Landau, C; Lange, RA; Page, RL; Willard, JE, 1996) |
| "Two hundred and ten patients with clinical evidence of heart failure, developing after an acute myocardial infarction, were randomized to treatment with the beta 1-receptor antagonist metoprolol 50-100 mg b." | 5.08 | Effects of beta receptor antagonists on left ventricular function in patients with clinical evidence of heart failure after myocardial infarction. A double-blind comparison of metoprolol and xamoterol. Echocardiographic results from the Metoprolol and Xam ( Erhardt, L; Eriksson, SV; Persson, H, 1996) |
| "The influence of the beta-blocker metoprolol on the capacity either of low-dose dobutamine echocardiography or the recently introduced enoximone echocardiography to detect viable dysfunctioning myocardium after myocardial infarction was investigated." | 5.08 | Identification of viable myocardium early after acute myocardial infarction under beta-blockade by enoximone echocardiography. ( Giovannini, E; Milazzotto, F; Minardi, G; Natale, E; Tubaro, M; Vajola, SF; Wang, F, 1997) |
| "The aim of this study is to describe the impact of early treatment with metoprolol on prognosis during 1 year of follow-up in patients with suspected acute myocardial infarction (AMI) and indirect signs of congestive heart failure (CHF)." | 5.08 | Effect of metoprolol on the prognosis for patients with suspected acute myocardial infarction and indirect signs of congestive heart failure (a subgroup analysis of the Göteborg Metoprolol Trial). ( Herlitz, J; Hjalmarson, A; Lindqvist, J; Swedberg, K; Waagstein, F, 1997) |
| "A randomized trial was conducted to assess the efficacy of amiodarone versus metoprolol or no antiarrhythmic treatment to suppress asymptomatic ectopic activity and improve survival in patients who have had myocardial infarction with a left ventricular ejection fraction of 20 to 45% and > or = 3 ventricular premature complexes per hour (pairs or runs)." | 5.07 | Comparison of the effects of amiodarone versus metoprolol on the frequency of ventricular arrhythmias and on mortality after acute myocardial infarction. SSSD Investigators. Spanish Study on Sudden Death. ( Bayes de Luna, A; Cosin, J; Guindo, J; Marrugat, J; Navarro-López, F, 1993) |
| "The purpose of this study was to determine the incidence of ventricular tachycardia and fibrillation without hypotension or heart failure after treatment with recombinant tissue-type plasminogen activator (rt-PA), anatomic correlates of their development, the effect of immediate intravenous metoprolol on their occurrence and the outcome of patients with these arrhythmias." | 5.07 | Incidence and significance of ventricular tachycardia and fibrillation in the absence of hypotension or heart failure in acute myocardial infarction treated with recombinant tissue-type plasminogen activator: results from the Thrombolysis in Myocardial In ( Berger, PB; Frederick, MM; Podrid, PJ; Ruocco, NA; Ryan, TJ, 1993) |
| "The effects of 5 and 10 mg of amlodipine and of placebo were compared in 21 patients with stable angina pectoris and multivessel coronary artery disease." | 5.07 | Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle. ( Julínek, J; Meluzín, J; Novák, M; Simek, P; Spinarová, L; Stejfa, M; Toman, J; Zeman, K, 1992) |
| "To evaluate the influence of acute beta-blockade on the ability of predischarge exercise test data to predict long-term prognosis in patients admitted for suspected acute myocardial infarction, patients randomized at hospital admission to intravenous metoprolol or placebo were studied." | 5.07 | Prognostic importance of predischarge exercise capacity for long-term mortality and non-fatal myocardial infarction in patients admitted for suspected acute myocardial infarction and treated with metoprolol. ( Rønnevik, PK; von der Lippe, G, 1992) |
| "A total of 5778 patients with suspected acute myocardial infarction were randomized to early intravenous metoprolol followed by oral treatment for 15 d, or to placebo." | 5.07 | Long-term prognosis after early intervention with metoprolol in suspected acute myocardial infarction: experiences from the MIAMI Trial. The MIAMI Trial Research Group. ( , 1991) |
| "To ascertain whether predischarge arteriography is beneficial in patients with acute myocardial infarction treated with recombinant tissue-type plasminogen activator (rt-PA), heparin and aspirin, the outcome of 197 patients in the Thrombolysis in Myocardial Infarction (TIMI) IIA study assigned to conservative management and routine predischarge coronary arteriography (routine catheterization group) was compared with the outcome of 1,461 patients from the TIMI IIB study assigned to conservative management without routine coronary arteriography unless ischemia recurred spontaneously or on predischarge exercise testing (selective catheterization group)." | 5.07 | Selective versus routine predischarge coronary arteriography after therapy with recombinant tissue-type plasminogen activator, heparin and aspirin for acute myocardial infarction. TIMI II Investigators. ( Babb, JD; Baim, DS; Braunwald, E; Chesebro, JH; Frederick, M; Gore, JM; Passamani, ER; Roberts, R; Rogers, WJ; Williams, DO, 1991) |
| "From a randomized multicenter trial with metoprolol in suspected acute myocardial infarction (n = 5778) we report on the outcome during a one-year follow-up in patients with confirmed infarction (n = 4106) in relation to whether or not they developed Q waves." | 5.06 | Prognosis during one year for patients with myocardial infarction in relation to the development of Q waves: experiences from the Miami trial. ( Herlitz, J; Hjalmarson, A; Karlson, BW, 1990) |
| "From a large randomized multicentre trial of metoprolol in suspected acute myocardial infarction (n = 5778) we report on the outcome during 1 year of follow-up, in relation to early diagnosis." | 5.06 | Mortality and morbidity during one year of follow-up in suspected acute myocardial infarction in relation to early diagnosis: experiences from the MIAMI trial. ( Herlitz, J; Hjalmarson, A; Karlson, BW, 1990) |
| "We used spectral analysis of heart rate variability (HRV) to study the effects of the calcium channel blockers diltiazem and nifedipine and the beta-blocker metoprolol on the sympathetic nervous system in patients following myocardial infarction." | 5.06 | Use of heart rate spectral analysis to study the effects of calcium channel blockers on sympathetic activity after myocardial infarction. ( Bekheit, S; Craelius, W; el-Sakr, A; el-Sherif, N; Rasheed, Q; Tangella, M, 1990) |
| "The effects of metoprolol, administered in the early stages of acute myocardial infarction was studied in 126 patients." | 5.06 | The effects of metoprolol given early in acute myocardial infarction on ventricular arrhythmias. ( Littler, WA; Murray, DP; Murray, RG, 1986) |
| "One-hundred and ninety-seven consecutive patients admitted for suspected acute myocardial infarction were randomized to double-blind treatment with intravenous followed by oral metoprolol or matching placebo within 24 hours (mean 6." | 5.06 | Effect of metoprolol on early exercise-induced ST-segment changes and ventricular arrhythmias in patients with suspected acute myocardial infarction. ( Abrahamsen, AM; Gundersen, T; Knutsen, H; Rønnevik, PK; Woie, L, 1989) |
| "From two large scale studies in patients with suspected acute myocardial infarction we report the outcome in diabetics after treatment with either metoprolol or placebo." | 5.06 | Effects of metoprolol on mortality and late infarction in diabetics with suspected acute myocardial infarction. Retrospective data from two large studies. ( Herlitz, J; Hjalmarson, A; Malmberg, K; Rydén, L, 1989) |
| "The effect of metoprolol on indices of infarct size and left ventricular function was compared with that of placebo in a double-blind randomized trial in patients with definite or suspected acute myocardial infarction." | 5.06 | Effect of early metoprolol injection followed by oral dosage on CK-MB release, and myocardial function in suspected acute myocardial infarction. A double-blind controlled study. ( Halinen, MO; Kuikka, J; Länsimies, E; Miettinen, H; Palomäki, P; Penttilä, I; Pyörälä, K, 1989) |
| "The Lopressor Intervention Trial (LIT) was a double-blind, randomized, placebo-controlled, multicentre study designed to evaluate the effect of oral metoprolol on overall mortality in patients surviving a recent acute myocardial infarction." | 5.06 | The Lopressor Intervention Trial: multicentre study of metoprolol in survivors of acute myocardial infarction. Lopressor Intervention Trial Research Group. ( , 1987) |
| "Mortality was analysed in relation to clinical and radiological signs of left ventricular failure in a double-blind randomized comparison of 154 post-myocardial infarction patients assigned to metoprolol (100 mg b." | 5.06 | Effect of metoprolol in postinfarction patients with increased heart size. ( Olsson, G; Rehnqvist, N, 1986) |
| "In a subsample of 223 patients participating in a double-blind trial with metoprolol in suspected acute myocardial infarction, body temperature during the first 5 days in hospital was recorded." | 5.06 | Body temperature in acute myocardial infarction and its relation to early intervention with metoprolol. ( Bengtson, A; Herlitz, J; Hjalmarson, A; Wilhelmsen, L, 1988) |
| "In 1,395 patients in the age range 40-74 years participating in a double-blind trial with metoprolol in suspected acute myocardial infarction morbidity and quality of life were assessed during the first 5 years after randomization." | 5.06 | Morbidity and quality of life 5 years after early intervention with metoprolol in suspected acute myocardial infarction. ( Bengtson, A; Herlitz, J; Hjalmarson, A; Wiklund, I, 1988) |
| "A double blind randomised study of 154 patients with myocardial infarction assigned to metoprolol (100 mg twice daily) and 147 assigned to placebo compared the effects of treatment in relation to health state over three years." | 5.06 | Quality of life after myocardial infarction: effect of long term metoprolol on mortality and morbidity. ( Lubsen, J; Olsson, G; Rehnqvist, N; van Es, GA, 1986) |
| "The effect of therapy on exercise performance during a 3-year follow-up after acute myocardial infarction (AMI) was evaluated in a double-blind randomized comparison between 154 patients given metoprolol (100 mg twice daily) and 147 patients given placebo." | 5.06 | Influence of long-term metoprolol treatment on early and late exercise test performance after acute myocardial infarction. ( Freyschuss, U; Olsson, G; Rehnqvist, N; Zetterquist, S, 1988) |
| "This study reports the mortality over a 5-year-period determined a double-blind trial, which evaluated the effect of early intervention with metoprolol in suspected acute myocardial infarction." | 5.06 | Effects on mortality during five years after early intervention with metoprolol in suspected acute myocardial infarction. ( Herlitz, J; Hjalmarson, A; Rydén, L; Swedberg, K; Waagstein, F, 1988) |
| "The outcome of postinfarction patients with a history of hypertension who participated in a randomized, double-blind, secondary prevention study with metoprolol or placebo treatment for 3 years has been evaluated." | 5.06 | Thromboatherosclerotic complications in hypertensives: results of the Stockholm Metoprolol (secondary prevention) Trial. ( Olsson, G, 1988) |
| "Fifty three of the 5778 patients included in the MIAMI (Metoprolol in Acute Myocardial Infarction) trial were investigated with long-term ECG recordings in order to evaluate the effect of acute beta-blockade on premature ventricular complexes in and after acute myocardial infarction." | 5.06 | Metoprolol in acute myocardial infarction reduces ventricular arrhythmias both in the early stage and after the acute event. ( Ekman, AM; Erhardt, L; Olsson, G; Rehnqvist, N, 1987) |
| "To determine the effect of beta-adrenergic blockade on the submaximal stress test after acute myocardial infarction (AMI), 36 post-AMI patients performed their treadmill test on 2 separate days, with and without metoprolol, in a double-blind, placebo-controlled, crossover design study." | 5.06 | Effect of metoprolol on the submaximal stress test performed early after acute myocardial infarction. ( Ades, PA; Hanson, JS; LaMountain, J; Shapiro, SM; Thomas, JD, 1987) |
| "In a prospective study, 20 patients with acute myocardial infarction were randomly assigned in a double-blind fashion to treatment with intravenous metoprolol followed by oral metoprolol or placebo." | 5.06 | Plasma catecholamine levels in acute myocardial infarction: influence of beta-adrenergic blockade and relation to central hemodynamics. ( Littler, WA; Murray, DP; Murray, RG; Watson, RD; Zezulka, AV, 1988) |
| "One of the secondary objectives of the MIAMI Trial which evaluated the role of the beta-1-selective blocker metoprolol in suspected acute myocardial infarction was to further assess whether early intervention with beta-blockade can limit infarct size." | 5.06 | Infarct size limitation after early intervention with metoprolol in the MIAMI Trial. ( Herlitz, J; Hjalmarson, A; Waldenström, J, 1988) |
| "In a double-blind randomized study of 154 postmyocardial infarction patients assigned to metoprolol (100 mg twice daily) and 147 patients assigned placebo, the outcome during a 3-year follow-up according to serum cholesterol concentrations was evaluated." | 5.06 | Postinfarction metoprolol treatment: effects on prognosis in relation to serum cholesterol concentrations. ( Olsson, G; Rehnqvist, N, 1987) |
| "The mortality and morbidity were assessed during a 2-year follow-up in an acute intervention trial in suspected acute myocardial infarction with metoprolol (a selective beta 1-blocker)." | 5.06 | The influence of early intervention in acute myocardial infarction on long-term mortality and morbidity as assessed in the Göteborg metoprolol trial. ( Herlitz, J; Hjalmarson, A; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wilhelmsson, C, 1986) |
| "The Stockholm Metoprolol Trial is a prospective double-blind placebo-controlled postmyocardial infarction study of 301 patients treated with metoprolol, 100 mg b." | 5.06 | Reduction of nonfatal reinfarctions in patients with a history of hypertension by chronic postinfarction treatment with metoprolol. ( Olsson, G; Rehnqvist, N, 1986) |
| "The aim of this investigation was to study central haemodynamics in initially uncomplicated acute myocardial infarction (AMI) with respect to natural history, relation to enzyme estimated infarct size, mortality and effects of metoprolol." | 5.06 | Central haemodynamics in acute myocardial infarction. Natural history, relation to enzyme release and effects of metoprolol. ( Held, P, 1986) |
| "The central haemodynamic effects of metoprolol in patients with acute myocardial infarction and with heart rate less than or equal to 65 beats min-1 have been investigated in a randomized double-blind trial." | 5.06 | Central haemodynamic effects of metoprolol early in acute myocardial infarction. A placebo controlled randomized study of patients with low heart rate. ( Held, PH; Hjalmarson, A; Rydén, L; Swedberg, K, 1986) |
| "In 39 patients who had been treated with metoprolol 100-200 mg daily or placebo for three years after acute myocardial infarction, serum lipids and lipoproteins were studied while the patients were on treatment as well as after its withdrawal." | 5.06 | Serum lipids and lipoproteins in ischaemic heart disease following withdrawal of long-term metoprolol treatment. ( Olsson, G; Rehnqvist, N; Rössner, S, 1987) |
| "The effect of metoprolol on mortality was compared with that of placebo in a double blind randomised trial in patients with definite or suspected acute myocardial infarction." | 5.05 | Effect on mortality of metoprolol in acute myocardial infarction. A double-blind randomised trial. ( Elmfeldt, D; Herlitz, J; Hjalmarson, A; Holmberg, S; Málek, I; Nyberg, G; Rydén, L; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Waldenström, J; Wedel, H; Wilhelmsen, L; Wilhelmsson, C, 1981) |
| "All patients with a presumptive diagnosis of myocardial infarction, who were seen within six hours of the onset of symptoms and had no reason for exclusion, were considered for entry into a trial to compare the effects of metoprolol and placebo on creatine kinase MB isoenzyme release." | 5.05 | Effect of very early intervention with metoprolol on myocardial infarct size. ( Barber, JM; Boyle, DM; Cran, G; Elwood, JH; Evans, AE; McIlmoyle, EL; Salathia, KS; Shanks, RG, 1983) |
| "In a double-blind randomized trial, 1,395 patients with suspected acute myocardial infarction (MI) were investigated to evaluate the possibility of limiting indirect signs of the size and severity of acute MI with the beta 1-selective adrenoceptor antagonist metoprolol." | 5.05 | Effect of metoprolol on indirect signs of the size and severity of acute myocardial infarction. ( Elmfeldt, D; Herlitz, J; Hjalmarson, A; Holmberg, S; Málek, I; Nyberg, G; Rydén, L; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Waldenström, J; Wedel, H; Wilhelmsen, L; Wilhelmsson, C, 1983) |
| "In the Göteborg Metoprolol Trial, 1395 patients with suspected acute myocardial infarction were, on admission, randomly allocated to double-blind treatment, 697 to placebo and 698 to metoprolol (15 mg i." | 5.05 | The Göteborg metoprolol trial. Effects on mortality and morbidity in acute myocardial infarction. ( Herlitz, J; Hjalmarson, A; Holmberg, S; Rydén, L; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Waldenström, J; Wedel, H; Wilhelmsen, L; Wilhelmsson, C, 1983) |
| "A total of 1395 patients aged 40 to 74 years were included in a double blind trial with the beta 1 selective blocker metoprolol in suspected acute myocardial infarction." | 5.05 | Effect of metoprolol on chest pain in acute myocardial infarction. ( Herlitz, J; Hjalmarson, A; Holmberg, S; Pennert, K; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wedel, H; Wilhelmsen, L, 1984) |
| "In a double blind study of metoprolol in the treatment of suspected acute myocardial infarction 698 patients (study group) received metoprolol and 697 a placebo (control group)." | 5.05 | Development of congestive heart failure after treatment with metoprolol in acute myocardial infarction. ( Herlitz, J; Hjalmarson, A; Holmberg, S; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wedel, H; Wilhelmsen, L; Wilhelmsson, C, 1984) |
| "In a double-blind trial, 30 patients with suspected acute myocardial infarction with onset of symptoms within the previous 24 h were randomized to treatment with 10 mg nifedipine/placebo orally 4 times a day during hospitalization." | 5.05 | Hemodynamic and clinical findings after combined therapy with metoprolol and nifedipine in acute myocardial infarction. ( Emanuelsson, H; Herlitz, J; Hjalmarson, A; Holmberg, S; Waagstein, F; Waldenström, A; Waldenström, J, 1984) |
| "The Göteborg Metoprolol Trial was a double-blind, placebo-controlled, stratified trial aimed at evaluating the effect of the beta 1-selective blocker, metoprolol, in suspected acute myocardial infarction and during 2 years of follow-up." | 5.05 | Göteborg Metoprolol Trial: design, patient characteristics and conduct. ( Herlitz, J; Holmberg, S; Pennert, K; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Waldenström, J; Wedel, H; Wilhelmsen, L, 1984) |
| "The effect of metoprolol on chest pain was compared with that of placebo in all randomized patients." | 5.05 | Göteborg Metoprolol Trial: effects on chest pain. ( Herlitz, J; Hjalmarson, A; Holmberg, S; Richterova, A; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wennerblom, B; Wilhelmsson, C, 1984) |
| "During a double-blind trial in which patients with suspected myocardial infarction received metoprolol or placebo, we analyzed the occurrence of ventricular tachyarrhythmias." | 5.05 | A double-blind trial of metoprolol in acute myocardial infarction. Effects on ventricular tachyarrhythmias. ( Ariniego, R; Arnman, K; Herlitz, J; Hjalmarson, A; Holmberg, S; Reyes, C; Rydén, L; Smedgård, P; Svedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wedel, H; Wilhelmsson, C; Yamamoto, M, 1983) |
| "The effect of metoprolol on mortality and morbidity after 15 days, was compared with that of placebo in a double-blind randomised international trial (the MIAMI trial) in patients with definite or suspected acute myocardial infarction (AMI)." | 5.05 | Metoprolol in acute myocardial infarction (MIAMI). A randomised placebo-controlled international trial. The MIAMI Trial Research Group. ( , 1985) |
| "The effects of early intervention with metoprolol in patients with suspected or definite acute myocardial infarction (AMI) have been assessed in a randomized, double-blind, placebo-controlled international study." | 5.05 | Metoprolol in acute myocardial infarction. Patients and methods. The MIAMI Trial Research Group. ( , 1985) |
| "The effect of metoprolol on platelet aggregation was investigated in a group of postmyocardial infarction (MI) patients." | 5.05 | ADP-induced platelet aggregation and metoprolol treatment of myocardial infarction patients. A controlled study. ( Kutti, J; Swedberg, K; Vedin, A; Vilén, L, 1985) |
| "A double-blind trial with the beta 1-selective blocker metoprolol in suspected acute myocardial infarction and during 3 months' follow-up included 1395 patients, aged 40-74 years, 698 on metoprolol and 697 on placebo." | 5.05 | Tolerability to treatment with metoprolol in acute myocardial infarction in relation to age. ( Herlitz, J; Hjalmarson, A; Holmberg, S; Pennert, K; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Waldenström, J; Wedel, H, 1985) |
| "The effects of metoprolol treatment in patients surviving acute myocardial infarction have been investigated in a double-blind randomized study." | 5.05 | Long-term treatment with metoprolol after myocardial infarction: effect on 3 year mortality and morbidity. ( Erhardt, L; Lundman, T; Olsson, G; Rehnqvist, N; Sjögren, A, 1985) |
| "The effect of metoprolol on the development of an acute myocardial infarction (AMI) during days 0 to 3 and on late first and recurrent infarctions during days 4 to 15 has been investigated." | 5.05 | Metoprolol in acute myocardial infarction. Development of myocardial infarction. The MIAMI Trial Research Group. ( , 1985) |
| "The central hemodynamic effects of metoprolol in acute myocardial infarction have been studied in a multicenter, double-blind, randomized trial." | 5.05 | Hemodynamic effects of metoprolol in acute myocardial infarction. A randomized, placebo-controlled multicenter study. ( Corbeij, HM; Dunselman, P; Held, PH; Hjalmarson, A; Murray, D; Swedberg, K, 1985) |
| "1 Ten patients with acute myocardial infarction were infused dobutamine in increasing doses up to 15 microgram kg--1 min--1." | 5.04 | The use of dobutamine in myocardial infarction for reversal of the cardiodepressive effect of metoprolol. ( Hjalmarson, AC; Malek, I; Waagstein, F, 1978) |
| "Although carvedilol, a nonselective beta-blocker with alpha-adrenergic blocking and multiple ancillary activities, has been demonstrated to be superior to metoprolol in chronic heart failure, it remains unclear whether the superiority of carvedilol still exists in myocardial infarction (MI)." | 4.95 | Meta-Analysis Comparing Metoprolol and Carvedilol on Mortality Benefits in Patients With Acute Myocardial Infarction. ( Chen, Z; Gao, X; Ju, J; Li, J; Xiong, W; Xu, H; Zhang, H, 2017) |
| "Because carvedilol is a unique vasodilating β blocker (BB) exerting antioxidant activity and pleiotropic effects, it was theorized that it may confer more potent beneficial effects on cardiovascular mortality and morbidity in acute myocardial infarction (AMI) and heart failure (HF) settings." | 4.89 | Meta-analysis of carvedilol versus beta 1 selective beta-blockers (atenolol, bisoprolol, metoprolol, and nebivolol). ( DiNicolantonio, JJ; Fares, H; Lavie, CJ; Menezes, AR; O'Keefe, JH, 2013) |
| "Carvedilol is a beta-adrenergic antagonist with vasodilatory properties (alpha1-antagonism), which has been extensively evaluated in the treatment of patients with heart failure." | 4.84 | Carvedilol: use in chronic heart failure. ( Doughty, RN; White, HD, 2007) |
| "During the intervening years since metoprolol was first reviewed in the Journal (1977), it has become widely used in the treatment of mild to moderate hypertension and angina pectoris." | 4.77 | Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders. ( Benfield, P; Brogden, RN; Clissold, SP, 1986) |
| "To find the effects of dapagliflozin in combination with metoprolol sustained-release tablets on cardiac function and prognosis in acute myocardial infarction patients after PCI." | 4.12 | Effects of Dapagliflozin in Combination with Metoprolol Sustained-Release Tablets on Prognosis and Cardiac Function in Patients with Acute Myocardial Infarction after PCI. ( Liu, Z; Zhang, H, 2022) |
| "To explore the effect of metoprolol tartrate tablets and recombinant human natriuretic peptide B (NPPB) on sudden cardiac death and malignant arrhythmias in patients with acute myocardial infarction and patients with heart failure (AMI-HF)." | 4.02 | Effect of metoprolol tartrate tablets and recombinant human B-type natriuretic peptide on the sudden cardiac death and malignant arrhythmias in patients with acute myocardial infarction and heart failure. ( Lin, Y; Liu, C; Yao, L; Zhang, L, 2021) |
| "Metoprolol is regarded as a first-line medicine for the treatment of myocardial infarction (MI)." | 3.96 | Metoprolol protects against myocardial infarction by inhibiting miR-1 expression in rats. ( Li, Z; Qin, W; Xiao, D; Xu, C; Yang, H; Zhang, H; Zhang, L; Zhang, Y, 2020) |
| "Metoprolol (Met) is widely applied in the treatment of myocardial infarction and coronary heart disease in clinic." | 3.96 | Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia. ( Kou, J; Lai, Q; Li, F; Liu, Z; Wang, H; Yu, B; Yuan, G, 2020) |
| "Metoprolol exerts a disruptive action on neutrophil dynamics during exacerbated inflammation, resulting in an infarct-limiting effect not observed with atenolol or propranolol." | 3.96 | Metoprolol exerts a non-class effect against ischaemia-reperfusion injury by abrogating exacerbated inflammation. ( Clemente-Moragón, A; Fuster, V; García-Prieto, J; Gómez, M; Ibáñez, B; Lalama, DV; Martínez, F; Oliver, E; Sánchez-Cabo, F; Villena-Gutiérrez, R, 2020) |
| " Ginseng Fruit Saponin (GFS) and Metoprolol are two drugs which have beneficial effects on the cardiovascular system in Myocardial Infarction (MI) mice." | 3.91 | Antidepressant-like effects of ginseng fruit saponin in myocardial infarction mice. ( Ge, Y; Geng, Q; Liu, J; Liu, M; Zhang, L, 2019) |
| " We discuss the case of a patient with new-onset atrial fibrillation receiving metoprolol for rate control on a background of pseudoephedrine use for allergic rhinitis leading to acute myocardial infarction from multivessel coronary vasospasm." | 3.85 | Acute Myocardial Infarction from Coronary Vasospasm Precipitated by Pseudoephedrine and Metoprolol Use. ( Goldsweig, AM; Malm, BJ; Meoli, EM, 2017) |
| "The β1-adrenergic-receptor (ADRB1) antagonist metoprolol reduces infarct size in acute myocardial infarction (AMI) patients." | 3.85 | Neutrophil stunning by metoprolol reduces infarct size. ( Bernardo, E; Bourio-Martínez, R; Crainiciuc, G; Del Valle, AS; Fernández-Jiménez, R; Fernández-Ortiz, A; Fuster, V; García-Lunar, I; García-Prieto, J; García-Ruiz, JM; Gómez, M; Hidalgo, A; Ibanez, B; Pizarro, G; Pun-García, A; Sanz-Rosa, D; Sreeramkumar, V; Villena-Gutiérrez, R, 2017) |
| "Metoprolol inhibits neutrophil-platelet interactions and reduces microvascular obstructions after acute myocardial infarction." | 3.85 | Stunning neutrophils changes the forecast: No more showers. ( King, KR, 2017) |
| "The ability of a chronic treatment with indacaterol, a new ultra-long-acting β2 -adrenoceptor agonist, to reverse cardiac remodelling and its effects in combination with metoprolol, a selective β1 -adrenoceptor antagonist, were investigated on myocardial infarction in a rat model of heart failure (HF)." | 3.81 | Effects of chronic treatment with the new ultra-long-acting β2 -adrenoceptor agonist indacaterol alone or in combination with the β1 -adrenoceptor blocker metoprolol on cardiac remodelling. ( Calzetta, L; Capuano, A; Donniacuo, M; Gritti, G; Martuscelli, E; Matera, MG; Orlandi, A; Rafaniello, C; Rinaldi, B; Rossi, F; Sodano, L, 2015) |
| "Mice treated with sorafenib or vehicle for 3 weeks underwent induced myocardial infarction (MI) after 1 week of treatment." | 3.80 | Sorafenib cardiotoxicity increases mortality after myocardial infarction. ( Barbe, M; Berretta, RM; Dunn, J; Duran, JM; Force, T; Gao, E; Gross, P; Houser, SR; Husain, S; Kubo, H; Lal, H; Makarewich, CA; Sharp, TE; Starosta, T; Trappanese, D; Vagnozzi, RJ; Yu, D, 2014) |
| "In order to examine the reversibility of heart failure due to myocardial infarction (MI) by β-adrenoceptor blockade, 12 weeks infarcted rats were treated with or without metoprolol (50 mg/kg/day) for 8 weeks." | 3.79 | Reversal of cardiac dysfunction and subcellular alterations by metoprolol in heart failure due to myocardial infarction. ( Babick, A; Dhalla, NS; Elimban, V; Zieroth, S, 2013) |
| " Metoprolol can prevent sympathetic nerve remodeling after myocardial infarction (MI), but the underlying mechanism is unclear." | 3.79 | Metoprolol-mediated amelioration of sympathetic nerve sprouting after myocardial infarction. ( Cheng, WJ; Hu, HS; Liu, J; Suo, F; Wang, Y; Xuan, YL; Xue, M; Yan, SH, 2013) |
| "This study evaluated the effects of early treatment with β-adrenergic blocker metoprolol on ventricular remodeling and function after acute myocardial infarction (AMI) by using high frequency ultrasound." | 3.78 | High-frequency ultrasound evaluation of effects of early treatment with metoprolol on myocardial inflammatory cytokine expression in rats with acute myocardial infarction. ( Gao, Y; Huang, L; Wu, W; Yang, Y; Zhang, J, 2012) |
| "Thirty Yorkshire-pigs underwent a reperfused myocardial infarction, being randomized to pre-reperfusion-metoprolol, post-reperfusion-metoprolol or placebo." | 3.77 | The cardioprotection granted by metoprolol is restricted to its administration prior to coronary reperfusion. ( Badimon, JJ; Badimon, L; Cimmino, G; Fuster, V; García, MJ; Hutter, R; Ibanez, B; Prat-González, S; Sanz, J; Vilahur, G, 2011) |
| " In this study, we characterised left ventricular thrombospondin-1 and -4 expression in rats treated with a beta-blocker metoprolol during the remodelling process in response to pressure overload and acute myocardial infarction." | 3.76 | Metoprolol treatment lowers thrombospondin-4 expression in rats with myocardial infarction and left ventricular hypertrophy. ( Aro, J; Leskinen, H; Luodonpää, M; Mustonen, E; Ruskoaho, H; Rysä, J; Vuolteenaho, O, 2010) |
| " More importantly, ruboxistaurin prevented death in wild-type mice throughout 10 weeks of pressure-overload stimulation, reduced ventricular dilation, enhanced ventricular performance, reduced fibrosis, and reduced pulmonary edema comparable to or better than metoprolol treatment." | 3.75 | Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach. ( Chen, X; Houser, SR; Kranias, EG; Leitges, M; Liu, Q; Lorenz, JN; Macdonnell, SM; Molkentin, JD, 2009) |
| "Several controlled studies with long-term administration of beta blockers in postinfarction patients have demonstrated a reduction in cardiac events and mortality." | 3.75 | Early intervention with a beta-blocking drug after acute myocardial infarction. ( Hjalmarson, A, 1984) |
| "To investigate the effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction (MI)." | 3.74 | [Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction]. ( Chen, H; Guo, CY; Li, HW; Li, ZZ; Shen, LH; Sun, T; Tang, CS, 2008) |
| "Metoprolol reduces post-MI ventricular arrhythmias, partly by altering the neural remodeling process." | 3.74 | Effects of prolonged metoprolol treatment on neural remodeling and inducible ventricular arrhythmias after myocardial infarction in rabbits. ( Cheng, WJ; Hu, HS; Shi, CW; Wang, Q; Wang, XL; Xing, QC; Xue, M; Yan, SH, 2007) |
| " The aim of this study was to investigate the effects of metoprolol on sympathetic remodeling and electrical remodeling at the infarcted border zone (IBZ) after myocardial infarction (MI)." | 3.74 | Effects of metoprolol on sympathetic remodeling and electrical remodeling at infarcted border zone after myocardial infarction in rabbits. ( Huang, C; Jian, X; Jiang, H; Lu, Z; Yang, B; Yu, Y; Zhao, D, 2007) |
| " A patient suffering from coronary artery disease and taking metoprolol and aspirin was stung by wasps and developed cutaneous allergic signs including rash, urticaria and orbital oedema." | 3.74 | Hymenoptera sting-induced Kounis syndrome: effects of aspirin and beta-blocker administration. ( Ioannidis, TI; Karpeta, MZ; Kounis, GN; Kounis, NG; Mazarakis, A; Notaras, SP; Rallis, DG; Tsintoni, AC, 2007) |
| "Emergency physicians should bear in mind that AMI can accompany the presentation of metoprolol overdose in those with coronary artery disease." | 3.74 | Cardiovascular toxicity due to metoprolol poisoning in a patient with coronary artery disease. ( Bozkurt, S; Kaynak, F; Topacoglu, H; Unverir, P, 2007) |
| " We aimed to verify whether the beta-blocker, metoprolol, and the pure heart-rate-reducing agent, ivabradine, have the same effects on haemodynamic function, ventricular remodeling, and Ca2+ handling in post-myocardial infarction (MI) heart failure in rat." | 3.74 | Effect of metoprolol and ivabradine on left ventricular remodelling and Ca2+ handling in the post-infarction rat heart. ( Mackiewicz, U; Maczewski, M, 2008) |
| " Here, we show that blockade of beta-adrenoceptors directly in the brain (chronic intracerebroventricular administration of metoprolol) attenuates the progression of left ventricular remodeling in a rat model of myocardial infarction-induced heart failure." | 3.74 | Beneficial effect of the central nervous system beta-adrenoceptor blockade on the failing heart. ( Bondar, SI; Gourine, A; Gourine, AV; Spyer, KM, 2008) |
| "The aim of study was to explore the effects of early beta-adrenergic blockade-metoprolol treatment on myocardial inflammatory cytokine expression and heart function in rats after acute myocardial infarction (AMI)." | 3.73 | [Effects of early treatment with metoprolol on myocardial inflammatory cytokine expression and heart function in rats with acute myocardial infarction]. ( Cheng, X; Ge, HX; Guo, ZQ; Li, B; Liao, YH; Liu, Y; Lu, BJ; Yang, YL; Zhang, JY; Zhang, L, 2005) |
| "We investigated the change of LV remodeling and function in a rat model of heart failure due to myocardial infarction (MI) with or without carvedilol (30 mg/kg/d) or metoprolol (60 mg/kg/d) treatment for 6 weeks (n = 9 in the MI plus carvedilol group, and n = 8 in every other group)." | 3.73 | Effect of beta-blockers on cardiac function and calcium handling protein in postinfarction heart failure rats. ( Hu, SJ; Hu, Y; Sun, YL; Wang, LH; Zhou, JY, 2005) |
| "To compare the beneficial effects of Atenolol and Metoprolol on cardiomyocyte apoptosis and related gene expressions after acute myocardial infarction (AMI) in rats." | 3.73 | [Effects of atenolol and metoprolol on cardiomyocyte apoptosis and related gene expression after acute myocardial infarction in rats]. ( Chen, JL; Chen, X; Chen, YF; Chen, ZJ; Gao, RL; Ruan, YM; Si, WX; Sun, RC; Tian, Y; Wang, QZ; Yang, YJ; Zhou, YW, 2006) |
| "We compared protective effects of a ss-adrenoceptor blocker (metoprolol; Met) and a If current (Ivabradine; Iva) in a rabbit model of myocardial infarction." | 3.73 | Comparison of a beta-blocker and an If current inhibitor in rabbits with myocardial infarction. ( Brockert, M; Gams, E; Langenbach, MR; Pomblum, VJ; Schepan, M; Schipke, JD; Schmitz-Spanke, S; Zirngibl, H, 2006) |
| "Metoprolol succinate was given to 60 patients with class I-III heart failure and ejection fraction <45% after myocardial infarction." | 3.72 | [Effect of metoprolol CR/XL on remodeling of the heart and cardiac rhythm disturbances after myocardial infarction in patients with chronic heart failure]. ( Churganova, LIu; Gavril'eva, SA; Ivanov, GG; Poltavskaia, MG; Sheianov, MV; Shumilova, KM; Syrkin, AL, 2003) |
| "The dose-related beneficial effects of carvedilol on survival in heart failure have been verified, however, the effects on left ventricular remodeling (LVRM) after acute myocardial infarction (AMI) have not been defined." | 3.72 | Comparison of metoprolol with low, middle and high doses of carvedilol in prevention of postinfarction left ventricular remodeling in rats. ( Chen, J; Chen, Z; Gao, R; Ruan, Y; Tang, Y; Wang, Y; Yang, Y, 2003) |
| "The Metoprolol CR/XL Randomized Intervention Trial in Chronic Heart Failure (MERIT-HF), the Cardiac Insufficiency Bisoprolol Study II (CIBIS-II), and the Carvedilol Prospective Randomized Cumulative Survival Study (COPERNICUS) have all demonstrated highly significant positive effects on total mortality as well as total mortality plus all-cause hospitalization in patients with heart failure." | 3.72 | How should subgroup analyses affect clinical practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF). ( Deedwania, P; Fagerberg, B; Ghali, J; Goldstein, S; Gottlieb, S; Hjalmarson, A; Kjekshus, J; Waagstein, F; Wedel, H; Wikstrand, J, 2003) |
| "Baroreflex sensitivity was assessed in 287 patients with history of myocardial infarction and left ventricular ejection fraction < or =40% by phenylephrine test and was found to be depressed (4." | 3.72 | [Correction of baroreflex sensitivity impairment and efficacy of prevention of sudden arrhythmic death in patients with postinfarction left ventricular dysfunction]. ( Bozhko, AA; Kanopskiĭ, SG; Staritskiĭ, AG, 2004) |
| "To compare the effects of carvedilol and metoprolol in preventing from left ventricular remodeling (LVRM) after acute myocardial infarction (AMI) in rats." | 3.71 | [Comparative effects of carvedilol and metoprolol in preventing from left ventricular remodeling after acute myocardial infarction in rats]. ( Chen, JL; Chen, ZJ; Gao, RL; Lu, SQ; Ruan, YM; Sun, RC; Tang, YD; Wang, PH; Yang, YJ; Zhang, P, 2001) |
| "Carvedilol, a selective alpha1 and non-selective beta-adrenoceptor antagonist and antioxidant, has been shown to provide significant cardiac protection in animal models of myocardial ischemia." | 3.70 | Comparison of metoprolol and carvedilol pharmacology and cardioprotection in rabbit ischemia and reperfusion model. ( Arch, JR; Cheng, HY; Feuerstein, G; Hieble, JP; Liu, GL; Ma, XL; Ruffolo, RR; Yue, TL, 1998) |
| " Of 10,991 myocardial infarction survivors dispensed atenolol, metoprolol, propranolol, or timolol, 9458 (86." | 3.70 | Age- and gender-related use of low-dose drug therapy: the need to manufacture low-dose therapy and evaluate the minimum effective dose. ( Anderson, GM; Clark, JP; Gurwitz, JH; Lau, P; Rochon, PA; Shear, NH; Tu, JV, 1999) |
| "The effects of chronic treatment with the beta-adrenoceptor antagonist metoprolol, the angiotensin converting enzyme inhibitor ramipril, their combination, or placebo on action potential configuration 6 weeks after myocardial infarction in rats were studied." | 3.70 | Effects of metoprolol and ramipril on action potentials after myocardial infarction in rats. ( Günther, J; Kamkin, A; Kiseleva, I; Scholz, H; Theres, H; Wagner, K, 2000) |
| "We administered oral metoprolol or no therapy to rats for 12 weeks after large myocardial infarction and subsequently examined left ventricular (LV) remodeling; myocardial tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta, and IL-6 expression; and NO." | 3.70 | beta-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling. ( Chandrasekar, B; Freeman, GL; Murray, DR; Prabhu, SD, 2000) |
| "This analysis was carried out to clarify the capacity of metoprolol to prevent cardiac events in Japanese post-myocardial infarction patients during a follow-up period of 16." | 3.70 | Retrospective analysis showing less cardiac events in post-myocardial infarction patients treated with metoprolol. Secondary Prevention Group. ( Hayashi, T; Inoki, T; Ishikawa, K; Kanamasa, K; Katayama, K; Kimura, A; Kitayama, K; Miyataka, M; Takenaka, T; Yabushita, H, 2000) |
| "We sought to compare the effects of two different beta-blockers, carvedilol and metoprolol, to an angiotensin-converting enzyme (ACE) inhibitor (captopril) on myocardial collagen deposition during healing and ventricular remodeling after myocardial infarction (MI)." | 3.70 | Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction. ( Chow, LT; Sanderson, JE; Wei, S, 2000) |
| "This study analyzed, with spectral techniques, the effects of atenolol or metoprolol on RR interval variability in 20 patients 4 weeks after the first uncomplicated myocardial infarction." | 3.69 | Effects of beta blockers (atenolol or metoprolol) on heart rate variability after acute myocardial infarction. ( La Rovere, MT; Lombardi, F; Malliani, A; Mortara, A; Sandrone, G; Torzillo, D, 1994) |
| "In 759 patients with acute myocardial infarction in whom serum activity of heat stable lactate dehydrogenase had been determined every 12 hours for 108 hours after randomisation in an early intervention trial with metoprolol." | 3.69 | Ten year mortality in relation to original size of myocardial infarct: results from the Gothenburg metoprolol study. ( Herlitz, J; Hjalmarson, A; Karlson, BW, 1994) |
| "The effects of metoprolol on early infarct expansion after acute myocardial infarction were studied in rats (n = 54) that underwent either left coronary artery ligation (MI) or sham operation." | 3.69 | Effects of metoprolol on early infarct expansion after acute myocardial infarction. ( Cohn, PF; Jain, P; Lillis, O, 1994) |
| "Pain intensity and the plasma concentrations of metoprolol and its major metabolite alpha-hydroxymetoprolol as well as noradrenaline (NA), adrenaline (A) and neuropeptide Y (NPY) were determined in patients with pain due to definite or suspected acute myocardial infarction (AMI) after graded metoprolol infusion." | 3.69 | Effects and pharmacokinetics of high dose metoprolol on chest pain in patients with suspected or definite acute myocardial infarction. ( Abdon, NJ; Everts, B; Hedner, T; Herlitz, J; Karlson, BW, 1997) |
| "One hundred thirty-one patients presenting with acute myocardial infarction (AMI) a mean of 3 hours after the onset of symptoms were treated with oral aspirin and intravenous thrombolytic therapy followed by heparin." | 3.68 | Safety of combined intravenous beta-adrenergic blockade (atenolol or metoprolol) and thrombolytic therapy in acute myocardial infarction. ( Commerford, PJ; Gordon, GD; Green, BK; Horak, AR; Millar, RN, 1992) |
| "The study aimed to compare the effects of thoracic epidural anaesthesia (TEA) with those of the beta-adrenoceptor blocker, metoprolol, on central haemodynamics in conscious rats with acute myocardial infarction." | 3.68 | Effects of thoracic epidural anaesthesia on central haemodynamics compared to cardiac beta adrenoceptor blockade in conscious rats with acute myocardial infarction. ( Blomberg, S; Ricksten, SE, 1990) |
| " A positive correlation was found between serum enzyme activity and most of the clinical variables studied, such as incidence of congestive heart failure, treatment with furosemide, incidence of hypotension, cardiogenic shock, pericarditis, post myocardial infarction syndrome, AV block III, and the duration of hospitalization." | 3.67 | Relationship between the enzymatically estimated infarct size and clinical findings in acute myocardial infarction. ( Herlitz, J; Hjalmarson, A; Waldenström, J, 1984) |
| "During the initial hospitalization, ventricular fibrillation (VF) developed in 6 metoprolol-treated patients (0." | 3.67 | Göteborg Metoprolol Trial: effects on arrhythmias. ( Edvardsson, N; Herlitz, J; Hjalmarson, A; Holmberg, S; Rydén, L; Swedberg, K; Waagstein, F; Waldenström, A, 1984) |
| "The acute effects of intravenous metoprolol were evaluated in 30 patients with myocardial infarction by means of serial hemodynamic and radionuclide measurements of left ventricular function." | 3.67 | Hemodynamic effects of intravenous metoprolol in acute myocardial infarction: the role of anatomic subsets in predicting patient response. ( Breisblatt, WM; Burns, MJ; Spaccavento, LJ; Waldo, DA, 1988) |
| "To determine the effects of intravenous metoprolol on left ventricular (LV) function in acute myocardial infarction (AMI), 16 patients were studied within 48 hours of Q-wave AMI (mean ejection fraction 47 +/- 6%, mean pulmonary artery wedge pressure 22 +/- 6 mm Hg) with high fidelity pressure and biplane cineventriculography before and after intravenous metoprolol (dose 12 +/- 4 mg)." | 3.67 | Effect of intravenous metoprolol on left ventricular performance in Q-wave acute myocardial infarction. ( Dell'Italia, LJ; Walsh, RA, 1989) |
| "To assess the intraoperative and postoperative hemodynamic effects of beta-blockade and its benefits in limiting myocardial ischemia and infarction, a group of 32 patients scheduled for abdominal aortic aneurysm (AAA) surgery (group 1) was treated with oral metoprolol immediately before surgery and with intravenous metoprolol during the postoperative period." | 3.67 | The hemodynamics of beta-blockade in patients undergoing abdominal aortic aneurysm repair. ( Baumann, FG; Bear, G; Becker, G; Berguson, P; Grossi, EA; Imparato, AM; Lamparello, PJ; Laub, G; Pasternack, PF; Riles, TS, 1987) |
| "Chronic treatment with metoprolol of postmyocardial infarction patients did not influence the response to an intravenous glucose tolerance test." | 3.67 | Effects of chronic metoprolol treatment on glucose tolerance after myocardial infarction. ( Olsson, G; Rehnqvist, N, 1987) |
| " and oral dosage regimen of metoprolol early in acute myocardial infarction has been evaluated." | 3.67 | Metoprolol in acute myocardial infarction. A pharmacokinetic and pharmacodynamic study. ( Held, PH; Regårdh, CG, 1986) |
| " Its short-term antiarrhythmic effects were compared with those of metoprolol, which has neither short-term class III nor membrane-stabilizing action, on reentrant ventricular arrhythmias produced by programmed stimulation in 17 conscious dogs 3 to 8 days after myocardial infarction." | 3.66 | Action of sotalol on potential reentrant pathways and ventricular tachyarrhythmias in conscious dogs in the late postmyocardial infarction phase. ( Brachmann, J; Cobbe, SM; Hoffman, E; Kübler, W; Ritzenhoff, A; Senges, J, 1983) |
| " Thirty-six subjects (healthy, severe angina pectoris, or acute myocardial infarction) were studied 15 minutes either after the beta 1-selective beta-blocking drug metoprolol had been administered in total doses of 2 and 10 mg intravenously or after pindolol, a beta blocker with intrinsic sympathomimetic activity (ISA), in total doses of 0." | 3.66 | Cardiac safety of acute beta blockade: intrinsic sympathomimetic activity is superior to beta-1 selectivity. ( Heikkilä, J; Nieminen, MS, 1982) |
| "Metoprolol, a cardioselective beta-receptor blocker, was administered to 12 patients three to ten hours after sustaining a transmural myocardial infarction, and the effect of the drug (10 mg i." | 3.66 | [Treatment of acute myocardial infarction with metoprolol (author's transl)]. ( Delius, W; Klein, G; Sack, D; Wirtzfeld, A, 1978) |
| "Metoprolol was administered as an initial dose of 15 mg intravenously, following 6-8 hours 100 mg/d orally." | 2.70 | [Effects of metoprolol on the signal averaged electrocardiogram and QT dispersion in acute myocardial infarction]. ( Akilli, A; Ceyhan, C; Onbaşili, OA; Tekten, T; Türkoğlu, C, 2002) |
| "Myocardial ischemia was quantified with adenosine 201Tl tomography (SPECT) performed 4." | 2.69 | Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study. ( Dakik, HA; Farmer, JA; He, ZX; Kleiman, NS; Mahmarian, JJ; Pratt, CM; Verani, MS; Wendt, JA, 1998) |
| "Treatment with metoprolol for two years after coronary artery bypass grafting did not significantly change exercise capacity or electrocardiographic signs of myocardial ischaemia." | 2.68 | Metoprolol treatment for two years after coronary bypass grafting: effects on exercise capacity and signs of myocardial ischaemia. ( Caidahl, K; Herlitz, J; Hjalmarson, A; Lurje, L; Sjöland, H, 1995) |
| "Heart block is common among patients with inferior infarction given thrombolytic therapy and is associated with increased mortality." | 2.67 | Incidence and prognostic implications of heart block complicating inferior myocardial infarction treated with thrombolytic therapy: results from TIMI II. ( Berger, PB; Faxon, DP; Frederick, MM; Jacobs, AK; Ruocco, NA; Ryan, TJ, 1992) |
| "In metoprolol treated patients in whom the arrhythmia frequency was reduced by greater than 75% after three days of treatment, mortality was lower as compared to those metoprolol treated patients who did not show this treatment response (3% vs 28%, P = 0." | 2.66 | Evaluation of antiarrhythmic effect of metoprolol treatment after acute myocardial infarction: relationship between treatment responses and survival during a 3-year follow-up. ( Olsson, G; Rehnqvist, N, 1986) |
| " No major adverse reactions related to the intervention were observed in either group." | 2.66 | The safety of combined thrombolysis and beta-adrenergic blockade in patients with acute myocardial infarction. A randomized study. ( Lawson, WE; Vlay, SC, 1988) |
| "Following withdrawal, ventricular arrhythmias during stress increased in 4 patients in the metoprolol group." | 2.66 | Cardiovascular reactivity to mental stress during gradual withdrawal of chronic postinfarction treatment with metoprolol. ( Hjemdahl, P; Olsson, G; Rehnqvist, N, 1986) |
| "The incidences of congestive heart failure, hypotension, AV blocks and ventricular arrhythmias were not significantly more common in the control group (8 vs." | 2.65 | Established beta-adrenergic receptor blocking therapy and acute myocardial infarction. A clinical study of risks and benefits. ( Berglund, U; Dahlström, U; Karlsson, E, 1980) |
| "Nifedipine is a calcium antagonist with established anti-vasospastic action in man and, possibly cardioprotective effects during ischaemia." | 2.65 | Acute myocardial ischaemia: what information can be expected in the near future from ongoing clinical trials with nifedipine? ( Hugenholtz, PG; Lubsen, J, 1983) |
| "Metoprolol 15 mg was given IV followed by a total daily dose of 200 mg/day." | 2.65 | Acute intervention with metoprolol in myocardial infarction. ( Hjalmarson, A, 1981) |
| "Acute myocardial infarction is caused by sudden coronary artery occlusion." | 2.47 | [Modulation of the beta-adrenergic system during acute myocardial infarction: rationale for a new clinical trial]. ( Fernández-Ortiz, A; Fuster, V; Ibáñez, B; Iñiguez, A; Jiménez-Borreguero, J; Macaya, C; Sánchez-Brunete, V; Sanz, G, 2011) |
| "Type 2 diabetes is becoming very common and is closely linked to physical inactivity and obesity." | 2.41 | Beta-blockers and diabetes: the bad guys come good. ( Cruickshank, JM, 2002) |
| "Metoprolol is a beta 1-selective adrenoceptor antagonist that is widely used in several indications." | 2.39 | Metoprolol: a pharmacoeconomic and quality-of-life evaluation of its use in hypertension, post-myocardial infarction and dilated cardiomyopathy. ( Benfield, P; Peters, DH, 1994) |
| " This study assesses the impact of β-blocker type and dosing on survival in patients with DM after MI." | 1.91 | Impact of Diabetes Mellitus on Benefit of β-Blocker Therapy After Myocardial Infarction. ( Abbott, JD; Bello, D; Blandon, C; Goldberger, JJ; Subačius, H; Zaatari, G, 2023) |
| " Beta-blocker dosage groups were >0% to12." | 1.62 | Comparison of Metoprolol Versus Carvedilol After Acute Myocardial Infarction. ( Fintel, DJ; Germano, JJ; Goldberger, JJ; Shani, J; Subacius, H; Zaatari, G, 2021) |
| " At follow-up, metoprolol dosage after up-titration, metoprolol steady-state trough plasma concentrations, hemodynamic parameters, potential metoprolol-induced adverse drug reactions and number of visits to the GP were measured." | 1.56 | Impact of genotype-predicted CYP2D6 metabolism on clinical effects and tolerability of metoprolol in patients after myocardial infarction - a prospective observational study. ( Anstensrud, AK; Fosshaug, LE; Haug, HJ; Molden, E; Muriq, H; Qazi, R; Spigset, O; Øie, E, 2020) |
| "Down syndrome is a genetic disorder known to cause many complications with lifelong effects." | 1.51 | Down syndrome, severe psoriasis, and increased risk for cardiovascular events. ( DʼAcunto, K; Sismour, B, 2019) |
| "Metoprolol was given 20 mg/kg/day for 5 weeks after MI surgery." | 1.48 | Comparison between renal denervation and metoprolol on the susceptibility of ventricular arrhythmias in rats with myocardial infarction. ( Chen, C; Geng, J; Huo, J; Jiang, W; Jiang, Z; Lu, D; Shan, Q; Xu, H, 2018) |
| "Heart attack (myocardial infarction) is a highly prevalent entity worldwide." | 1.40 | Health and cost benefits associated with the use of metoprolol in heart attack patients. ( Fernández-Jiménez, R; Ibanez, B, 2014) |
| "Metoprolol treatment and ghrelin treatment in KO mice prevented excessive sympathetic activation, decreased plasma epinephrine and norepinephrine levels, and improved heart function and survival rate after MI." | 1.39 | Excessive sympathoactivation and deteriorated heart function after myocardial infarction in male ghrelin knockout mice. ( Kangawa, K; Kishimoto, I; Mao, Y; Miyazato, M; Otani, K; Tokudome, T, 2013) |
| "Metoprolol can inhibit the expression of c-fos and has a positive therapeutic effect on rats after AMI; the involvement effect of metoprolol on myocardial infarction might be correlated with its effect on the inhibition of c-fos." | 1.39 | The effect of c-fos on acute myocardial infarction and the significance of metoprolol intervention in a rat model. ( Ge, J; Goldstein, S; He, B; Li, Y; Ruiz, G; Zhang, M; Zhang, S, 2013) |
| "Clenbuterol pretreatment provides significant cardioprotection against ischaemia/reperfusion injury and this is mediated by the beta(2)-adrenoceptor-G(i)-protein signalling." | 1.36 | Beta(2)-adrenoceptor agonist clenbuterol reduces infarct size and myocardial apoptosis after myocardial ischaemia/reperfusion in anaesthetized rats. ( Feng, M; Fu, Q; Hu, B; Liu, H; Wang, X; Xiang, J; Zhang, Q, 2010) |
| "Metoprolol treatment for 2 weeks improved LV systolic function." | 1.35 | Divergent effects of losartan and metoprolol on cardiac remodeling, c-kit+ cells, proliferation and apoptosis in the left ventricle after myocardial infarction. ( Kerkelä, R; Kubin, AM; Leskinen, H; Pieviläinen, O; Ruskoaho, H; Serpi, R; Soini, Y; Tenhunen, O; Tolonen, AM; Vaskivuo, T, 2009) |
| "Cells isolated from the heart scar were identified as myofibroblasts." | 1.35 | Regulatory influence of melatonin on collagen accumulation in the infarcted heart scar. ( Dabrowski, R; Drobnik, J; Jakubowski, L; Karbownik-Lewińska, M; Olczak, S; Szczepanowska, A; Słotwińska, D, 2008) |
| "With appropriate protocol, MDCT is safe and accurate in assessing the severity of IRA and the number of diseased vessels during the first week after AMI." | 1.33 | Safety and accuracy of multidetector row computed tomography for early assessment of residual stenosis of the infarct-related artery and the number of diseased vessels after acute myocardial infarction. ( Chiou, KR; Hsiao, SH; Liu, CP; Mar, GY; Pan, HB; Wu, MT; Yang, CF, 2005) |
| "Acute myocardial infarction is a rare complication of mitral stenosis." | 1.33 | Acute myocardial infarction in a patient with severe unrecognized mitral stenosis. ( Bajraktari, G; Beqiri, A; Berisha, I; Elezi, S; Kastrati, S; Manaj, R; Thaqi, S, 2006) |
| "Metoprolol and/or PQQ were given at the onset of reperfusion to mimic clinical treatment." | 1.33 | Comparison of pyrroloquinoline quinone and/or metoprolol on myocardial infarct size and mitochondrial damage in a rat model of ischemia/reperfusion injury. ( Cecchini, G; Karliner, JS; Li, L; Simonis, U; Teerlink, JR; Zhou, HZ; Zhu, BQ, 2006) |
| "The treatment with metoprolol 1 mg/kg/h was initiated in the third week post-infarct for a period of 6 weeks." | 1.32 | Selective beta1-blockade attenuates post-infarct remodelling without improvement in myocardial energy metabolism and function in rats with heart failure. ( Bollano, E; Omerovic, E; Soussi, B; Waagstein, F, 2003) |
| "Myocardial infarction is rare during pregnancy." | 1.31 | [Myocardial infarction, pregnancy and anesthesia]. ( Diar, N; Rezig, K; Walcker, JL, 2000) |
| "The treatment with metoprolol was given by subcutaneously implanted minipumps and was initiated at 3 days postinfarct and during the period of 4 weeks." | 1.31 | Selective beta(1)-blockade improves cardiac bioenergetics and function and decreases neuroendocrine activation in rats during early postinfarct remodeling. ( Bollano, E; Hjalmarson , A; Kujacic, V; Madhu, B; Mobini, R; Omerovic, E; Soussi, B; Waagstein, F, 2001) |
| "Metoprolol treatment (60 mg/kg/day via gastric gavage) was started on the second day after surgery and continued until sacrifice at 6 weeks after myocardial infarction." | 1.31 | Metoprolol attenuates postischemic depressed myocardial function in papillary muscles isolated from normal and postinfarction rat hearts. ( Ding, B; Min, JY; Morgan, JP; Sullivan, MF; Wang, JF, 2001) |
| "Treatment with growth hormone alone or in combination with metoprolol preserved left ventricular function after MI." | 1.31 | Growth hormone alone or combined with metoprolol preserves cardiac function after myocardial infarction in rats. ( Bengtsson, BA; Bergh, CH; Bollano, E; Caidahl, K; Isgaard, J; Kjellström, C; Kujacic, V; Omerovic, E; Waagstein, F, 2001) |
| "Metoprolol treatment tended to normalize LV end-diastolic pressure (LVEDP)." | 1.30 | Comparative efficacy of a DA2/alpha2 agonist and a beta-blocker in reducing adrenergic drive and cardiac fibrosis in an experimental model of left ventricular dysfunction after coronary artery occlusion. ( Bernasconi, R; Bongrani, S; Calvillo, L; Fiordaliso, F; Jeremic, G; Latini, R; Luvarà, G; Masson, S; Razzetti, R; Rondelli, I; Torri, M, 1998) |
| "Acute myocardial infarction is characterized by a more pronounced rise in plasma ANP concentration in hypertensive patients than in those without a history of hypertension." | 1.29 | Elevated plasma atrial natriuretic peptide concentrations in hypertensive patients with acute myocardial infarction. ( Górecki, A; Ignatowska-Switalska, H; Januszewicz, A; Kochanowski, J; Lapiński, M; Opolski, G; Stolarz, P; Słomka, K; Wocial, B, 1995) |
| "Many of the arrhythmias other than ventricular fibrillation had little hemodynamic consequence and did not require treatment." | 1.28 | Associated reactions during and immediately after rtPA infusion. ( Linnik, W; Ramos, R; Tintinalli, JE, 1989) |
| "Metoprolol was administered intravenously (0." | 1.28 | Coronary reperfusion by thrombolysis and early beta-adrenergic blockade in acute experimental myocardial infarction. ( De Geest, H; Jang, IK; Van de Werf, F; Vanhaecke, J, 1989) |
| "Ventricular arrhythmias other than VF are common in acute infarction and, for emotional rather than scientific reasons, often are aggressively treated." | 1.27 | Treatment and prophylaxis of ventricular arrhythmias in acute myocardial infarction. ( Campbell, RW, 1983) |
| "Indirect signs of congestive heart failure tended to be less severe in patients given metoprolol within 12 hours of the onset of symptoms than in those given placebo." | 1.27 | Göteborg Metoprolol Trial: clinical observations. ( Hartford, M; Herlitz, J; Hjalmarson, A; Pennert, K; Waagstein, F; Waldenström, A; Wedel, H; Wilhelmsson, C, 1984) |
| "More metoprolol-treated than placebo-treated patients withdrew because of cardiovascular adverse experience mainly during the very early phase." | 1.27 | Göteborg Metoprolol Trial: tolerance. ( Herlitz, J; Hjalmarson, A; Pennert, K; Vedin, A; Wedel, H; Wilhelmsen, L; Wilhelmsson, C, 1984) |
| "Correspondingly, ventricular arrhythmias and fibrillation were almost completely prevented by metoprolol, d-sotalol or verapamil, but increased by lidocaine." | 1.27 | Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion. ( Gülker, H; Haverkamp, W; Hindricks, G; Thale, J, 1987) |
| "5 mg) given intracoronary, a dose that shifted the isoproterenol dose-response curve to the right, slowed ventricular tachycardia from 174 +/- 7." | 1.27 | Autonomic control of ventricular tachycardia: direct effects of beta-adrenergic blockade in 24 hour old canine myocardial infarction. ( Constantin, L; Martins, JB, 1987) |
| "Experience with treatment of myocardial infarction in man has shown that beta-blocking agents are well tolerated in patients presenting in hemodynamically stable condition (Killip groups I and II)." | 1.26 | [Use of beta-adrenergic blocking agents in acute myocardial infarction (author's transl)]. ( Himmler, FC; Klein, G; Schmidt, G; Wirtzfeld, A, 1981) |
| "The arrhythmias were prevented by higher doses of the calcium antagonist verapamil which, however, decreased the survival times." | 1.26 | Comparative investigation of the effects of metoprolol, propranolol, practolol, and verapamil in the acute phase of experimental myocardial infarction. ( Bernauer, W, 1982) |
| " What remains to be solved is the dosage level." | 1.26 | Clinical experiences with prenalterol as an antidote to Beta-adrenoceptor blockade. ( Kulling, P, 1982) |
| " Three days post-AMI the dose-response curve for isoproterenol of right ventricular dP/dtmax was significantly depressed, while the inotropic effect of histamine was not impaired." | 1.26 | Impaired beta-adrenergic stimulation in the uninvolved ventricle post-acute myocardial infarction: reversible defect due to excessive circulating catecholamine-induced decline in number and affinity of beta-receptors. ( Baumann, G; Blömer, H; Blümel, G; Erhardt, WD; Felix, SB; Ludwig, L; Riess, G, 1981) |
| "Prenalterol was administered intravenously in four increasing doses to a cumulative dose of 5." | 1.26 | Central and peripheral haemodynamic effects of prenalterol in patients with coronary heart disease. ( Carlsen, JE; Hartling, OJ; Svendsen, TL; Trap-Jensen, J, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 186 (37.42) | 18.7374 |
| 1990's | 91 (18.31) | 18.2507 |
| 2000's | 135 (27.16) | 29.6817 |
| 2010's | 66 (13.28) | 24.3611 |
| 2020's | 19 (3.82) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C | 2 |
| Tian, J | 1 |
| He, Z | 1 |
| Xiong, W | 2 |
| He, Y | 1 |
| Liu, S | 1 |
| Chen, X | 3 |
| Fu, S | 1 |
| Xu, W | 1 |
| Liu, C | 1 |
| Yao, L | 1 |
| Zhang, L | 4 |
| Lin, Y | 1 |
| Bogush, N | 1 |
| Tan, L | 1 |
| Naqvi, E | 1 |
| Calvert, JW | 2 |
| Graham, RM | 1 |
| Taylor, WR | 1 |
| Naqvi, N | 1 |
| Husain, A | 1 |
| Li, M | 1 |
| Zheng, C | 1 |
| Kawada, T | 1 |
| Uemura, K | 1 |
| Inagaki, M | 1 |
| Saku, K | 1 |
| Sugimachi, M | 1 |
| Zhang, H | 3 |
| Liu, Z | 2 |
| Motawea, KR | 1 |
| Gaber, H | 1 |
| Singh, RB | 1 |
| Swed, S | 1 |
| Elshenawy, S | 1 |
| Talat, NE | 1 |
| Elgabrty, N | 1 |
| Shoib, S | 1 |
| Wahsh, EA | 1 |
| Chébl, P | 1 |
| Reyad, SM | 1 |
| Rozan, SS | 1 |
| Aiash, H | 1 |
| Zaatari, G | 2 |
| Bello, D | 1 |
| Blandon, C | 1 |
| Abbott, JD | 1 |
| Subačius, H | 2 |
| Goldberger, JJ | 2 |
| Kleinbongard, P | 1 |
| Lieder, HR | 1 |
| Skyschally, A | 1 |
| Heusch, G | 1 |
| Qin, W | 1 |
| Li, Z | 1 |
| Xiao, D | 1 |
| Zhang, Y | 3 |
| Yang, H | 2 |
| Xu, C | 1 |
| Sismour, B | 1 |
| DʼAcunto, K | 1 |
| Anstensrud, AK | 1 |
| Molden, E | 1 |
| Haug, HJ | 1 |
| Qazi, R | 1 |
| Muriq, H | 1 |
| Fosshaug, LE | 1 |
| Spigset, O | 1 |
| Øie, E | 1 |
| Lai, Q | 1 |
| Yuan, G | 1 |
| Wang, H | 1 |
| Kou, J | 1 |
| Yu, B | 1 |
| Li, F | 1 |
| Lorca, R | 1 |
| Jiménez-Blanco, M | 1 |
| García-Ruiz, JM | 6 |
| Pizarro, G | 6 |
| Fernández-Jiménez, R | 7 |
| García-Álvarez, A | 5 |
| Fernández-Friera, L | 5 |
| Lobo-González, M | 2 |
| Fuster, V | 13 |
| Rossello, X | 2 |
| Ibáñez, B | 16 |
| Marciszek, M | 1 |
| Paterek, A | 1 |
| Oknińska, M | 1 |
| Mackiewicz, U | 2 |
| Mączewski, M | 2 |
| Ponnapureddy, R | 1 |
| Roy, SD | 1 |
| Parekh, J | 1 |
| Liu, K | 1 |
| Clemente-Moragón, A | 1 |
| Gómez, M | 2 |
| Villena-Gutiérrez, R | 2 |
| Lalama, DV | 1 |
| García-Prieto, J | 5 |
| Martínez, F | 1 |
| Sánchez-Cabo, F | 1 |
| Oliver, E | 1 |
| Fintel, DJ | 1 |
| Germano, JJ | 1 |
| Shani, J | 1 |
| Giannakopoulos, G | 1 |
| Noble, S | 1 |
| Zhang, JG | 1 |
| Dai, SP | 1 |
| Liu, H | 2 |
| Xu, ZS | 1 |
| Meoli, EM | 1 |
| Goldsweig, AM | 1 |
| Malm, BJ | 1 |
| Bernardo, E | 1 |
| Pun-García, A | 1 |
| García-Lunar, I | 3 |
| Crainiciuc, G | 1 |
| Sreeramkumar, V | 1 |
| Bourio-Martínez, R | 1 |
| Del Valle, AS | 1 |
| Sanz-Rosa, D | 3 |
| Fernández-Ortiz, A | 5 |
| Hidalgo, A | 1 |
| Dariolli, R | 1 |
| Naghetini, MV | 1 |
| Marques, EF | 1 |
| Takimura, CK | 1 |
| Jensen, LS | 1 |
| Kiers, B | 1 |
| Tsutsui, JM | 1 |
| Mathias, W | 1 |
| Lemos Neto, PA | 1 |
| Krieger, JE | 1 |
| King, KR | 1 |
| Li, J | 1 |
| Chen, Z | 2 |
| Gao, X | 1 |
| Ju, J | 1 |
| Xu, H | 2 |
| Richards, JR | 1 |
| Horowitz, BZ | 1 |
| Jacka, MJ | 1 |
| Guyatt, G | 1 |
| Mizera, R | 1 |
| Van Vlymen, J | 1 |
| Ponce de Leon, D | 1 |
| Schricker, T | 1 |
| Bahari, MY | 1 |
| Lv, B | 1 |
| Afzal, L | 1 |
| Plou García, MP | 1 |
| Wu, X | 1 |
| Nigro Maia, L | 1 |
| Arrieta, M | 1 |
| Rao-Melacini, P | 1 |
| Devereaux, PJ | 3 |
| Zhang, K | 1 |
| Tang, YD | 2 |
| Ojamaa, K | 1 |
| Li, Y | 3 |
| Saini, AS | 1 |
| Carrillo-Sepulveda, MA | 1 |
| Rajagopalan, V | 1 |
| Gerdes, AM | 1 |
| Jiang, W | 1 |
| Huo, J | 1 |
| Lu, D | 1 |
| Jiang, Z | 1 |
| Geng, J | 1 |
| Shan, Q | 1 |
| Khwaja, S | 1 |
| Mahmood, T | 1 |
| Siddiqui, HH | 1 |
| Bykov, K | 1 |
| Gagne, JJ | 1 |
| Wang, B | 1 |
| Choudhry, NK | 1 |
| Liu, M | 1 |
| Liu, J | 2 |
| Geng, Q | 1 |
| Ge, Y | 1 |
| Mao, Y | 1 |
| Tokudome, T | 1 |
| Otani, K | 1 |
| Kishimoto, I | 1 |
| Miyazato, M | 1 |
| Kangawa, K | 1 |
| Babick, A | 1 |
| Elimban, V | 1 |
| Zieroth, S | 1 |
| Dhalla, NS | 1 |
| Fonarow, G | 1 |
| Wang, Y | 2 |
| Suo, F | 1 |
| Hu, HS | 2 |
| Xue, M | 2 |
| Cheng, WJ | 2 |
| Xuan, YL | 1 |
| Yan, SH | 2 |
| Ndrepepa, G | 1 |
| Kastrati, A | 1 |
| Macaya, C | 4 |
| Sánchez-Brunete, V | 6 |
| Mateos, A | 4 |
| Iñiguez, A | 4 |
| Jiménez-Borreguero, J | 3 |
| López-Romero, P | 2 |
| Goicolea, J | 3 |
| Ruiz-Mateos, B | 2 |
| Bastante, T | 3 |
| Arias, M | 2 |
| Iglesias-Vázquez, JA | 2 |
| Rodriguez, MD | 3 |
| Escalera, N | 3 |
| Acebal, C | 2 |
| Cabrera, JA | 3 |
| Valenciano, J | 2 |
| Pérez de Prado, A | 1 |
| Fernández-Campos, MJ | 2 |
| Casado, I | 2 |
| García-Rubira, JC | 2 |
| Cuellas, C | 2 |
| Hernández-Antolín, R | 2 |
| Albarrán, A | 3 |
| Fernández-Vázquez, F | 2 |
| de la Torre-Hernández, JM | 2 |
| Pocock, S | 3 |
| Sanz, G | 3 |
| Lim, GB | 1 |
| Karlson, BW | 12 |
| Dellborg, M | 5 |
| Gullestad, L | 1 |
| Aberg, J | 1 |
| Sugg, J | 1 |
| Herlitz, J | 62 |
| Zhang, J | 2 |
| Qiang, CC | 1 |
| Li, WJ | 2 |
| Liu, LJ | 1 |
| Lin, XX | 1 |
| Cheng, YJ | 1 |
| Tang, K | 1 |
| Yao, FJ | 1 |
| Wu, SH | 1 |
| Barreiro, MV | 2 |
| de Miguel, A | 1 |
| Parra-Fuertes, JJ | 1 |
| Sánchez-González, J | 1 |
| Pardillos, L | 1 |
| Nieto, B | 1 |
| Jiménez, A | 1 |
| Abejón, R | 1 |
| Martínez de Vega, V | 1 |
| López-Melgar, B | 1 |
| Guzman, G | 1 |
| Mirelis, JG | 1 |
| Zamorano, JL | 1 |
| Escaned, J | 1 |
| Antoniucci, D | 1 |
| Duran, JM | 1 |
| Makarewich, CA | 1 |
| Trappanese, D | 1 |
| Gross, P | 1 |
| Husain, S | 1 |
| Dunn, J | 1 |
| Lal, H | 1 |
| Sharp, TE | 1 |
| Starosta, T | 1 |
| Vagnozzi, RJ | 1 |
| Berretta, RM | 1 |
| Barbe, M | 1 |
| Yu, D | 2 |
| Gao, E | 2 |
| Kubo, H | 1 |
| Force, T | 1 |
| Houser, SR | 2 |
| Furuichi, Y | 1 |
| Sakamoto, A | 1 |
| Cheng, K | 1 |
| Wei, MQ | 1 |
| Jia, GL | 1 |
| Wang, HC | 1 |
| Luan, RH | 1 |
| Guo, WY | 1 |
| Zong, XJ | 1 |
| Zhou, X | 1 |
| Huang, BS | 1 |
| Chen, A | 1 |
| Ahmad, M | 1 |
| Wang, HW | 1 |
| Leenen, FH | 1 |
| Argulian, E | 1 |
| Messerli, FH | 2 |
| de Prado, AP | 1 |
| Huertas, P | 1 |
| Bravo, J | 1 |
| Flores-Arias, J | 1 |
| Chayán-Zas, L | 1 |
| Corral, E | 1 |
| Akgüllü, Ç | 1 |
| Eryılmaz, U | 1 |
| Güngör, H | 1 |
| Huyut, A | 1 |
| Zencir, C | 1 |
| Hekim, T | 1 |
| DiNicolantonio, JJ | 3 |
| Fuchs, FD | 1 |
| O'Keefe, JH | 2 |
| Nizamuddin, SL | 1 |
| Broderick, DK | 1 |
| Minehart, RD | 1 |
| Kamdar, BB | 1 |
| Roolvink, V | 1 |
| Rasoul, S | 1 |
| Ottervanger, JP | 1 |
| Dambrink, JH | 1 |
| Lipsic, E | 1 |
| van der Horst, IC | 1 |
| de Smet, B | 1 |
| Kedhi, E | 1 |
| Marcel Gosselink, AT | 1 |
| Piek, JJ | 1 |
| Van't Hof, AW | 1 |
| Opie, LH | 2 |
| Merli, GJ | 1 |
| Weitz, HH | 1 |
| Bergmark, BA | 1 |
| Galper, BZ | 1 |
| Shah, AM | 1 |
| Bhatt, DL | 1 |
| Rinaldi, B | 1 |
| Donniacuo, M | 1 |
| Sodano, L | 1 |
| Gritti, G | 1 |
| Martuscelli, E | 1 |
| Orlandi, A | 1 |
| Rafaniello, C | 1 |
| Rossi, F | 1 |
| Calzetta, L | 1 |
| Capuano, A | 1 |
| Matera, MG | 1 |
| Manov, A | 1 |
| Gopalakrishnan, PP | 1 |
| Subramaniam, S | 1 |
| Wardi, M | 1 |
| White, J | 1 |
| Yue, Y | 1 |
| Dou, L | 1 |
| Wang, X | 2 |
| Xue, H | 1 |
| Song, Y | 1 |
| Li, X | 1 |
| Kelloniemi, A | 1 |
| Aro, J | 2 |
| Näpänkangas, J | 1 |
| Koivisto, E | 1 |
| Mustonen, E | 2 |
| Ruskoaho, H | 3 |
| Rysä, J | 2 |
| Seo, GW | 1 |
| Kim, DK | 1 |
| Kim, KH | 1 |
| Seol, SH | 1 |
| Jin, HY | 1 |
| Yang, TH | 1 |
| Ahn, Y | 1 |
| Jeong, MH | 1 |
| Song, PS | 1 |
| Kim, DI | 1 |
| Newby, LK | 1 |
| Kloner, RA | 2 |
| Braunwald, E | 2 |
| Grisanti, LA | 1 |
| Gumpert, AM | 1 |
| Traynham, CJ | 1 |
| Gorsky, JE | 1 |
| Repas, AA | 1 |
| Carter, RL | 1 |
| García, AP | 1 |
| Rabinowitz, JE | 1 |
| Koch, WJ | 1 |
| Tilley, DG | 1 |
| Essandoh, MK | 1 |
| Dalia, AA | 1 |
| George, BS | 1 |
| Flores, AS | 1 |
| Otey, AJ | 1 |
| Kirtane, AJ | 1 |
| Broderick, TM | 1 |
| Rao, SV | 1 |
| Shchukin, IuV | 1 |
| Vachev, AN | 1 |
| Surkova, EA | 1 |
| Germanov, AV | 1 |
| Golovin, EA | 1 |
| D'iachkov, VA | 1 |
| Lange, M | 1 |
| Smul, TM | 1 |
| Redel, A | 1 |
| Lotz, C | 1 |
| Jazbutyte, V | 1 |
| Schnupp, V | 1 |
| Roewer, N | 1 |
| Kehl, F | 1 |
| Horowitz, JD | 1 |
| Arstall, MA | 1 |
| Zeitz, CJ | 1 |
| Beltrame, JF | 1 |
| Andersen, SS | 1 |
| Hansen, ML | 1 |
| Gislason, GH | 1 |
| Folke, F | 1 |
| Schramm, TK | 1 |
| Fosbøl, E | 1 |
| Sørensen, R | 1 |
| Rasmussen, S | 1 |
| Abildstrøm, SZ | 1 |
| Madsen, M | 1 |
| Køber, L | 1 |
| Torp-Pedersen, C | 3 |
| Goryachkina, K | 2 |
| Burbello, A | 2 |
| Boldueva, S | 2 |
| Babak, S | 2 |
| Bergman, U | 2 |
| Bertilsson, L | 2 |
| Bangalore, S | 1 |
| Gluud, C | 1 |
| Wetterslev, J | 1 |
| Yang, XY | 1 |
| Wu, XM | 1 |
| Wang, S | 1 |
| Wang, Q | 2 |
| Kovacs, K | 1 |
| Hanto, K | 1 |
| Bognar, Z | 1 |
| Tapodi, A | 1 |
| Bognar, E | 1 |
| Kiss, GN | 1 |
| Szabo, A | 1 |
| Rappai, G | 1 |
| Kiss, T | 1 |
| Sumegi, B | 1 |
| Gallyas, F | 1 |
| Bernardon, M | 1 |
| Limone, A | 1 |
| Businelli, C | 1 |
| Maso, GP | 1 |
| Piccoli, M | 1 |
| Alberico, S | 1 |
| Sun, T | 1 |
| Shen, LH | 1 |
| Chen, H | 1 |
| Li, HW | 1 |
| Guo, CY | 1 |
| Li, ZZ | 1 |
| Tang, CS | 1 |
| Rolfo, F | 1 |
| Bobbio, M | 1 |
| Angeli, F | 1 |
| Cavallini, C | 1 |
| Ulu, N | 1 |
| Henning, RH | 1 |
| Goris, M | 1 |
| Schoemaker, RG | 1 |
| van Gilst, WH | 1 |
| Quinaglia e Silva, JC | 1 |
| Munhoz, DB | 1 |
| Morato, TN | 1 |
| Gurgel, A | 1 |
| Macedo, AC | 1 |
| Sever, P | 1 |
| Sposito, AC | 1 |
| Björkander, I | 4 |
| Forslund, L | 6 |
| Ericson, M | 2 |
| Rehnqvist, N | 26 |
| Hjemdahl, P | 8 |
| Kahan, T | 4 |
| Priebe, HJ | 1 |
| Patel, RA | 1 |
| Glover, DK | 1 |
| Broisat, A | 1 |
| Kabul, HK | 1 |
| Ruiz, M | 1 |
| Goodman, NC | 1 |
| Kramer, CM | 2 |
| Meerdink, DJ | 1 |
| Linden, J | 1 |
| Beller, GA | 1 |
| Alonso-Coello, P | 1 |
| Alvarez, C | 1 |
| Cruz, P | 1 |
| Torán, L | 1 |
| De Nadal, M | 1 |
| Martínez, M | 1 |
| Paniagua, P | 1 |
| Mases, A | 1 |
| Urrutia, G | 1 |
| Liu, Q | 1 |
| Macdonnell, SM | 1 |
| Kranias, EG | 1 |
| Lorenz, JN | 1 |
| Leitges, M | 1 |
| Molkentin, JD | 1 |
| Karakurt, O | 1 |
| Akdemir, R | 1 |
| Cimmino, G | 3 |
| Prat-González, S | 3 |
| Vilahur, G | 2 |
| Hutter, R | 2 |
| García, MJ | 2 |
| Sanz, J | 3 |
| Badimon, L | 1 |
| Badimon, JJ | 3 |
| Kent, DM | 1 |
| Trikalinos, TA | 1 |
| Fasullo, S | 1 |
| Cannizzaro, S | 1 |
| Maringhini, G | 2 |
| Ganci, F | 1 |
| Giambanco, F | 1 |
| Vitale, G | 1 |
| Pinto, V | 1 |
| Migliore, G | 1 |
| Torres, D | 1 |
| Sarullo, FM | 1 |
| Paterna, S | 5 |
| Di Pasquale, P | 5 |
| Poldermans, D | 1 |
| Gualandro, DM | 1 |
| Calderaro, D | 1 |
| Yu, PC | 1 |
| Marques, AC | 1 |
| Caramelli, B | 1 |
| Leskinen, H | 2 |
| Luodonpää, M | 1 |
| Vuolteenaho, O | 1 |
| Serpi, R | 1 |
| Tolonen, AM | 1 |
| Tenhunen, O | 1 |
| Pieviläinen, O | 1 |
| Kubin, AM | 1 |
| Vaskivuo, T | 1 |
| Soini, Y | 1 |
| Kerkelä, R | 1 |
| Zhang, Q | 1 |
| Xiang, J | 1 |
| Hu, B | 1 |
| Feng, M | 1 |
| Fu, Q | 1 |
| Remme, WJ | 3 |
| Giannarelli, C | 1 |
| Garcia, M | 1 |
| Flier, S | 1 |
| Buhre, WF | 1 |
| van Klei, WA | 1 |
| Edwards, J | 1 |
| Goodman, SG | 1 |
| Yan, RT | 1 |
| Welsh, RC | 1 |
| Kornder, JM | 1 |
| Deyoung, JP | 1 |
| Chauret, D | 1 |
| Picard, JP | 1 |
| Eagle, KA | 1 |
| Yan, AT | 1 |
| Hackam, DG | 1 |
| Kiselev, AR | 2 |
| Gridnev, VI | 2 |
| Prokhorov, MD | 2 |
| Karavaev, AS | 1 |
| Posnenkova, OM | 2 |
| Ponomarenko, VI | 2 |
| Bezruchko, BP | 1 |
| Chen, B | 1 |
| Jiang, S | 1 |
| Xie, YP | 1 |
| Guo, A | 1 |
| Kutschke, W | 1 |
| Zimmerman, K | 1 |
| Weiss, RM | 1 |
| Miller, FJ | 1 |
| Anderson, ME | 1 |
| Song, LS | 1 |
| Swiatkiewicz, I | 1 |
| Kozinski, M | 1 |
| Magielski, P | 1 |
| Gierach, J | 1 |
| Fabiszak, T | 1 |
| Kubica, A | 1 |
| Sukiennik, A | 1 |
| Navarese, EP | 1 |
| Odrowaz-Sypniewska, G | 1 |
| Kubica, J | 1 |
| Kezerashvili, A | 1 |
| Marzo, K | 1 |
| De Leon, J | 1 |
| Zhang, S | 1 |
| Zhang, M | 1 |
| Goldstein, S | 3 |
| Ge, J | 1 |
| He, B | 1 |
| Ruiz, G | 1 |
| Wu, W | 1 |
| Huang, L | 1 |
| Gao, Y | 1 |
| Yang, Y | 2 |
| Held, C | 4 |
| Billing, E | 1 |
| Eriksson, SV | 5 |
| Näsman, P | 2 |
| Lavie, CJ | 1 |
| Fares, H | 1 |
| Menezes, AR | 1 |
| Wikstrand, J | 6 |
| Hjalmarson, A | 63 |
| Waagstein, F | 32 |
| Fagerberg, B | 2 |
| Kjekshus, J | 2 |
| Wedel, H | 15 |
| Cruickshank, JM | 1 |
| Bali, HK | 1 |
| Vijayvergiya, R | 1 |
| Banarjee, S | 1 |
| Kumar, N | 1 |
| Syrkin, AL | 3 |
| Poltavskaia, MG | 3 |
| Shumilova, KM | 1 |
| Ivanov, GG | 1 |
| Churganova, LIu | 2 |
| Sheianov, MV | 1 |
| Gavril'eva, SA | 1 |
| Yang, YJ | 2 |
| Zhang, P | 1 |
| Ruan, YM | 2 |
| Lu, SQ | 1 |
| Sun, RC | 2 |
| Wang, PH | 1 |
| Gao, RL | 2 |
| Chen, JL | 2 |
| Chen, ZJ | 2 |
| Lebedeva, NB | 1 |
| Lebedev, OV | 1 |
| Berns, SA | 1 |
| Barbarash, LS | 1 |
| Barbarash, NA | 1 |
| Barbarash, OL | 1 |
| Jánosi, A | 1 |
| Ghali, JK | 1 |
| Czuriga, I | 1 |
| Klibaner, M | 1 |
| Omerovic, E | 3 |
| Bollano, E | 3 |
| Soussi, B | 2 |
| Tang, Y | 1 |
| Ruan, Y | 1 |
| Gao, R | 1 |
| Chen, J | 1 |
| Ghali, J | 1 |
| Deedwania, P | 1 |
| Gottlieb, S | 1 |
| Evrengul, H | 1 |
| Dursunoglu, D | 1 |
| Kayikcioglu, M | 1 |
| Can, L | 1 |
| Tanriverdi, H | 1 |
| Kaftan, A | 1 |
| Kilic, M | 1 |
| von Haehling, S | 1 |
| Cappato, R | 2 |
| Boczor, S | 1 |
| Kuck, KH | 1 |
| Rossow, CF | 1 |
| Minami, E | 1 |
| Chase, EG | 1 |
| Murry, CE | 1 |
| Santana, LF | 1 |
| Ahmed, A | 1 |
| Dell'Italia, LJ | 2 |
| Ahmet, I | 3 |
| Krawczyk, M | 2 |
| Heller, P | 1 |
| Moon, C | 1 |
| Lakatta, EG | 3 |
| Talan, MI | 3 |
| Kanopskiĭ, SG | 1 |
| Staritskiĭ, AG | 1 |
| Bozhko, AA | 1 |
| Prendergast, HM | 1 |
| Soorya, N | 1 |
| Erickson, T | 1 |
| Bonnemeier, H | 2 |
| Ortak, J | 2 |
| Tölg, R | 3 |
| Witt, M | 3 |
| Schmidt, J | 2 |
| Wiegand, UK | 2 |
| Bode, F | 2 |
| Schunkert, H | 2 |
| Richardt, G | 3 |
| Poole-Wilson, PA | 2 |
| Swedberg, K | 29 |
| Cleland, JG | 2 |
| Di Lenarda, A | 2 |
| Hanrath, P | 1 |
| Komajda, M | 2 |
| Lutiger, B | 1 |
| Metra, M | 2 |
| Scherhag, A | 2 |
| Skene, A | 1 |
| Cheng, X | 1 |
| Liao, YH | 1 |
| Li, B | 1 |
| Yang, YL | 1 |
| Zhang, JY | 1 |
| Lu, BJ | 1 |
| Ge, HX | 1 |
| Liu, Y | 1 |
| Guo, ZQ | 1 |
| Tepliakov, AT | 1 |
| Kuznetsova, AV | 1 |
| Stepacheva, TA | 1 |
| D'iakova, ML | 1 |
| Shilov, SN | 1 |
| Bolotskaia, LA | 1 |
| Kowey, PR | 1 |
| Chiou, KR | 1 |
| Wu, MT | 1 |
| Hsiao, SH | 1 |
| Mar, GY | 1 |
| Pan, HB | 1 |
| Yang, CF | 1 |
| Liu, CP | 1 |
| Bichan, NA | 1 |
| Bykova, EF | 1 |
| Gorbatovskiĭ, IaA | 1 |
| Pakhtusova, NI | 1 |
| Mishchenko, EP | 1 |
| Kotarova, LV | 1 |
| Sun, YL | 1 |
| Hu, SJ | 1 |
| Wang, LH | 1 |
| Hu, Y | 1 |
| Zhou, JY | 1 |
| Redelmeier, D | 1 |
| Scales, D | 1 |
| Kopp, A | 1 |
| Molchanova, IV | 1 |
| Chaplygin, AV | 1 |
| Sabatine, MS | 1 |
| Chen, ZM | 1 |
| Pan, HC | 1 |
| Chen, YP | 1 |
| Peto, R | 1 |
| Collins, R | 1 |
| Jiang, LX | 1 |
| Xie, JX | 1 |
| Liu, LS | 1 |
| Kucinsky, R | 1 |
| Goldhaber, S | 1 |
| Tavel, ME | 1 |
| Atar, I | 1 |
| Korkmaz, ME | 1 |
| Atar, IA | 1 |
| Gulmez, O | 1 |
| Ozin, B | 1 |
| Bozbas, H | 1 |
| Erol, T | 1 |
| Aydinalp, A | 1 |
| Yildirir, A | 1 |
| Yucel, M | 1 |
| Muderrisoglu, H | 1 |
| Bajraktari, G | 1 |
| Kastrati, S | 1 |
| Manaj, R | 1 |
| Berisha, I | 1 |
| Thaqi, S | 1 |
| Beqiri, A | 1 |
| Elezi, S | 1 |
| Borja, J | 1 |
| García, O | 1 |
| Donado, E | 1 |
| Izquierdo, I | 1 |
| Bhala, N | 1 |
| Taggar, J | 1 |
| Karthikeyan, G | 1 |
| Schwarz, B | 1 |
| Kurz, T | 1 |
| Kurowski, V | 1 |
| Hartmann, F | 1 |
| Geist, V | 1 |
| Basat, O | 1 |
| Ucak, S | 1 |
| Seber, S | 1 |
| Oztekin, E | 1 |
| Altuntas, Y | 1 |
| Drozdz, J | 1 |
| Bode, C | 1 |
| Hohnloser, SH | 1 |
| Dorian, P | 1 |
| Roberts, R | 4 |
| Gent, M | 1 |
| Israel, CW | 1 |
| Fain, E | 1 |
| Champagne, J | 1 |
| Connolly, SJ | 1 |
| Guyatt, GH | 1 |
| Leslie, K | 1 |
| Villar, JC | 1 |
| Monteri, VM | 1 |
| Choi, P | 1 |
| Giles, JW | 1 |
| Yusuf, S | 3 |
| Wang, XL | 1 |
| Xing, QC | 1 |
| Shi, CW | 1 |
| Zhu, BQ | 1 |
| Simonis, U | 1 |
| Cecchini, G | 1 |
| Zhou, HZ | 1 |
| Li, L | 1 |
| Teerlink, JR | 1 |
| Karliner, JS | 1 |
| Ee, PL | 1 |
| Kempen, PM | 1 |
| Nakashidze, NM | 1 |
| Machavariani, PT | 1 |
| Garton, M | 1 |
| Chen, YF | 1 |
| Tian, Y | 1 |
| Zhou, YW | 1 |
| Wang, QZ | 1 |
| Si, WX | 1 |
| Langenbach, MR | 1 |
| Schmitz-Spanke, S | 1 |
| Brockert, M | 1 |
| Schepan, M | 1 |
| Pomblum, VJ | 1 |
| Gams, E | 1 |
| Zirngibl, H | 1 |
| Schipke, JD | 1 |
| Jiang, H | 1 |
| Lu, Z | 1 |
| Yu, Y | 2 |
| Zhao, D | 1 |
| Jian, X | 1 |
| Yang, B | 1 |
| Huang, C | 1 |
| Ioannidis, TI | 1 |
| Mazarakis, A | 1 |
| Notaras, SP | 1 |
| Karpeta, MZ | 1 |
| Tsintoni, AC | 1 |
| Kounis, GN | 1 |
| Rallis, DG | 1 |
| Kounis, NG | 1 |
| Almquist, T | 1 |
| Doughty, RN | 1 |
| White, HD | 1 |
| Rinfret, S | 1 |
| Abrahamowicz, M | 1 |
| Tu, J | 1 |
| Humphries, K | 1 |
| Eisenberg, MJ | 1 |
| Richard, H | 1 |
| Austin, PC | 1 |
| Pilote, L | 1 |
| Baxter, AD | 1 |
| Kanji, S | 1 |
| Wang, P | 1 |
| Zaragoza, C | 1 |
| Holman, W | 1 |
| Anderson, S | 1 |
| Spark, P | 1 |
| Moullet, C | 1 |
| Lukas, MA | 1 |
| Ruta, J | 1 |
| Ptaszyński, P | 1 |
| Maciejewski, M | 1 |
| Goch, JH | 1 |
| Chizyński, K | 1 |
| Unverir, P | 1 |
| Topacoglu, H | 1 |
| Bozkurt, S | 1 |
| Kaynak, F | 1 |
| Speidl, WS | 1 |
| Pinero, A | 1 |
| Bespiatov, AB | 1 |
| Dovgalevskiĭ, PIa | 1 |
| Kotel'nikova, EV | 1 |
| Mrdovic, IB | 1 |
| Savic, LZ | 1 |
| Perunicic, JP | 2 |
| Asanin, MR | 1 |
| Lasica, RM | 2 |
| Jelena, MM | 1 |
| Matic, MD | 1 |
| Vasiljevic, ZM | 2 |
| Ostojic, MC | 1 |
| Kastratović, DA | 1 |
| Spasić, MB | 1 |
| Matić, M | 1 |
| Blagojević, DP | 1 |
| Mijalković, DN | 1 |
| Antonijević, NM | 1 |
| Marković, SZ | 1 |
| Gojković-Bukarica, L | 1 |
| Stojiljkovic, MP | 1 |
| Jones, DR | 1 |
| Nikolić-Kokić, AL | 1 |
| Chockalingam, A | 1 |
| Tejwani, L | 1 |
| Aggarwal, K | 1 |
| Dellsperger, KC | 2 |
| Andreev, DA | 1 |
| Svet, AV | 1 |
| Sarkisova, EA | 1 |
| Kalashnikov, VIu | 1 |
| Fox, K | 1 |
| Borer, JS | 1 |
| Camm, AJ | 1 |
| Danchin, N | 1 |
| Ferrari, R | 1 |
| Lopez Sendon, JL | 1 |
| Steg, PG | 1 |
| Tardif, JC | 1 |
| Tavazzi, L | 1 |
| Tendera, M | 1 |
| Zhao, J | 1 |
| Qu, XF | 2 |
| Zhao, CY | 1 |
| Cao, FL | 1 |
| Zhou, T | 1 |
| Li, WM | 1 |
| Huang, YL | 2 |
| Ahrens, W | 1 |
| Hagemeier, C | 1 |
| Mühlbauer, B | 1 |
| Pigeot, I | 1 |
| Püntmann, I | 1 |
| Reineke, A | 1 |
| Steinbach, M | 1 |
| Timm, J | 1 |
| Albert, NM | 1 |
| Fareed, FN | 1 |
| Chan, G | 1 |
| Hoffman, RS | 1 |
| Li, JJ | 1 |
| Li, KS | 1 |
| Xi, Y | 1 |
| Yue, L | 1 |
| Wang, GZ | 1 |
| Zhu, W | 1 |
| Woo, AY | 1 |
| Morrell, C | 1 |
| Poosala, S | 1 |
| Xiao, RP | 1 |
| Gourine, A | 1 |
| Bondar, SI | 1 |
| Spyer, KM | 1 |
| Gourine, AV | 1 |
| Schmitto, JD | 1 |
| Hein, S | 1 |
| Bräuer, A | 1 |
| Popov, AF | 1 |
| Quintel, M | 1 |
| Schöndube, FA | 1 |
| Drobnik, J | 1 |
| Karbownik-Lewińska, M | 1 |
| Szczepanowska, A | 1 |
| Słotwińska, D | 1 |
| Olczak, S | 1 |
| Jakubowski, L | 1 |
| Dabrowski, R | 1 |
| Dahlström, U | 1 |
| Berglund, U | 1 |
| Karlsson, E | 1 |
| Wirtzfeld, A | 4 |
| Klein, G | 3 |
| Himmler, FC | 1 |
| Schmidt, G | 1 |
| Elmfeldt, D | 5 |
| Holmberg, S | 17 |
| Málek, I | 7 |
| Nyberg, G | 3 |
| Rydén, L | 12 |
| Vedin, A | 16 |
| Waldenström, A | 18 |
| Waldenström, J | 18 |
| Wilhelmsen, L | 10 |
| Wilhelmsson, C | 10 |
| Bernauer, W | 1 |
| Heikkilä, J | 2 |
| Nieminen, MS | 3 |
| Moser, M | 1 |
| Gorlin, R | 1 |
| Moss, AJ | 1 |
| Hamm, CW | 1 |
| Thandroyen, FT | 1 |
| Kulling, P | 1 |
| Staessen, J | 1 |
| Bulpitt, C | 1 |
| Cattaert, A | 1 |
| Fagard, R | 1 |
| Vanhees, L | 1 |
| Amery, A | 1 |
| Julian, DG | 1 |
| Griggs, TR | 1 |
| Wagner, GS | 1 |
| Gettes, LS | 1 |
| Pratt, CM | 2 |
| Ribeiro, LG | 2 |
| Vacheron, A | 1 |
| Baubion, N | 1 |
| Delage, F | 1 |
| Delius, W | 3 |
| Weisswange, A | 1 |
| Jackson, EA | 1 |
| Sullman, SA | 1 |
| Rotmensch, HH | 1 |
| Vlasses, PH | 1 |
| Ferguson, RK | 1 |
| Frishman, WH | 1 |
| Furberg, CD | 1 |
| Friedewald, WT | 1 |
| Tomov, I | 1 |
| Willerson, JT | 2 |
| Buja, LM | 1 |
| Gillis, AM | 1 |
| Clusin, WT | 1 |
| Baumann, G | 3 |
| Riess, G | 2 |
| Erhardt, WD | 2 |
| Felix, SB | 2 |
| Ludwig, L | 2 |
| Blümel, G | 1 |
| Blömer, H | 3 |
| Schrader, J | 1 |
| Heidecke, CD | 1 |
| Loher, U | 1 |
| Sebening, F | 1 |
| Boyle, DM | 3 |
| Barber, JM | 3 |
| McIlmoyle, EL | 3 |
| Salathia, KS | 3 |
| Evans, AE | 2 |
| Cran, G | 2 |
| Elwood, JH | 2 |
| Shanks, RG | 3 |
| Khan, AH | 1 |
| Lubsen, J | 6 |
| Hugenholtz, PG | 1 |
| Pennert, K | 6 |
| Olsson, G | 22 |
| Emanuelsson, H | 3 |
| Vik-Mo, H | 1 |
| Maroko, PR | 1 |
| Yellon, DM | 1 |
| Downey, JM | 1 |
| Hearse, DJ | 1 |
| Cobbe, SM | 1 |
| Hoffman, E | 1 |
| Ritzenhoff, A | 1 |
| Brachmann, J | 1 |
| Kübler, W | 1 |
| Senges, J | 1 |
| Campbell, RW | 1 |
| Lange, R | 1 |
| Cortellaro, M | 1 |
| Boschetti, C | 1 |
| Antoniazzi, V | 1 |
| Polli, EE | 1 |
| de Gaetano, G | 1 |
| De Blasi, A | 1 |
| Gerna, M | 1 |
| Pezzi, L | 1 |
| Garattini, S | 1 |
| Ejdebäck, J | 1 |
| Edvardsson, N | 1 |
| Hartford, M | 2 |
| Richterova, A | 1 |
| Wennerblom, B | 2 |
| Ernst, E | 1 |
| Matrai, A | 1 |
| Brugger, P | 1 |
| Wihelmsson, C | 1 |
| Ariniego, R | 2 |
| Arnman, K | 1 |
| Reyes, C | 1 |
| Smedgård, P | 1 |
| Svedberg, K | 1 |
| Yamamoto, M | 1 |
| Lundman, T | 3 |
| Melcher, A | 2 |
| Estrada-Yamamoto, E | 1 |
| Reyes, CP | 1 |
| von Essen, R | 1 |
| Merx, W | 1 |
| Neis, W | 1 |
| Ritz, R | 1 |
| Svendsen, TL | 1 |
| Carlsen, JE | 1 |
| Hartling, OJ | 1 |
| Trap-Jensen, J | 1 |
| Molinis, G | 1 |
| Valente, M | 1 |
| Tuniz, D | 1 |
| Maisano, G | 1 |
| Di Benedetto, A | 1 |
| Cipolla, A | 1 |
| Badalamenti, E | 1 |
| Scilabra, G | 1 |
| Ahnve, S | 1 |
| Erhardt, L | 7 |
| Sjögren, A | 3 |
| Evans, A | 1 |
| Navarro-López, F | 1 |
| Cosin, J | 1 |
| Marrugat, J | 1 |
| Guindo, J | 1 |
| Bayes de Luna, A | 1 |
| Zmudka, K | 3 |
| Dubiel, J | 3 |
| Vanhaecke, J | 5 |
| Flameng, W | 4 |
| De Geest, H | 6 |
| Persson, H | 3 |
| Rythe'n-Alder, E | 1 |
| Sjöland, H | 1 |
| Caidahl, K | 2 |
| Lurje, L | 2 |
| Park, KC | 1 |
| Forman, DE | 1 |
| Wei, JY | 1 |
| Górecki, A | 1 |
| Januszewicz, A | 1 |
| Opolski, G | 1 |
| Lapiński, M | 1 |
| Wocial, B | 1 |
| Ignatowska-Switalska, H | 1 |
| Słomka, K | 1 |
| Kochanowski, J | 1 |
| Stolarz, P | 1 |
| Fernandez, AR | 1 |
| Sequeira, RF | 1 |
| Chakko, S | 1 |
| Correa, LF | 1 |
| de Marchena, EJ | 1 |
| Chahine, RA | 1 |
| Franceour, DA | 1 |
| Myerburg, RJ | 1 |
| Parrinello, G | 1 |
| Bucca, V | 3 |
| Caracausi, R | 1 |
| Pipitone, F | 1 |
| Licata, G | 2 |
| Osterziel, KJ | 1 |
| Magatti, M | 1 |
| Kern, KB | 1 |
| Hilwig, RW | 1 |
| Warner, A | 1 |
| Basnight, M | 1 |
| Ewy, GA | 1 |
| McDonald, KM | 1 |
| Rector, T | 1 |
| Carlyle, PF | 1 |
| Francis, GS | 1 |
| Cohn, JN | 1 |
| Sandrone, G | 1 |
| Mortara, A | 1 |
| Torzillo, D | 1 |
| La Rovere, MT | 1 |
| Malliani, A | 1 |
| Lombardi, F | 1 |
| Kobayashi, S | 1 |
| Tadokoro, H | 1 |
| Sjöquist, PO | 1 |
| Haendchen, RV | 1 |
| Corday, E | 1 |
| Cherng, WJ | 1 |
| Liang, CS | 1 |
| Hood, WB | 1 |
| Jain, P | 1 |
| Lillis, O | 1 |
| Cohn, PF | 1 |
| Berger, PB | 2 |
| Ruocco, NA | 3 |
| Ryan, TJ | 3 |
| Frederick, MM | 3 |
| Podrid, PJ | 1 |
| Santarelli, P | 1 |
| Lanza, GA | 1 |
| Biscione, F | 1 |
| Natale, A | 1 |
| Corsini, G | 1 |
| Riccio, C | 1 |
| Occhetta, E | 1 |
| Rossi, P | 1 |
| Gronda, M | 1 |
| Makmur, J | 1 |
| Aune, S | 1 |
| Karlsson, T | 2 |
| Mølgaard, H | 1 |
| Mickley, H | 1 |
| Pless, P | 1 |
| Bjerregaard, P | 1 |
| Møller, M | 1 |
| Tuininga, YS | 1 |
| Crijns, HJ | 2 |
| Brouwer, J | 2 |
| van den Berg, MP | 1 |
| Man in't Veld, AJ | 1 |
| Mulder, G | 1 |
| Lie, KI | 2 |
| Kontopoulos, AG | 2 |
| Athyros, VG | 2 |
| Papageorgiou, AA | 2 |
| Papadopoulos, GV | 1 |
| Avramidis, MJ | 1 |
| Boudoulas, H | 2 |
| Pavia, L | 1 |
| Orlando, G | 1 |
| Myers, J | 1 |
| Maestri, M | 1 |
| Rusconi, C | 1 |
| Keeley, EC | 2 |
| Page, RL | 2 |
| Lange, RA | 2 |
| Willard, JE | 1 |
| Landau, C | 1 |
| Hillis, LD | 3 |
| Bonaduce, D | 1 |
| Marciano, F | 1 |
| Petretta, M | 1 |
| Joglar, JA | 1 |
| Natale, E | 1 |
| Minardi, G | 1 |
| Wang, F | 1 |
| Tubaro, M | 1 |
| Giovannini, E | 1 |
| Vajola, SF | 1 |
| Milazzotto, F | 1 |
| Tygesen, H | 1 |
| Everts, B | 3 |
| Abdon, NJ | 2 |
| Hedner, T | 3 |
| Lindqvist, J | 3 |
| Kardos, A | 1 |
| Long, V | 1 |
| Bryant, J | 1 |
| Singh, J | 1 |
| Sleight, P | 3 |
| Casadei, B | 1 |
| Latini, R | 1 |
| Masson, S | 1 |
| Jeremic, G | 1 |
| Luvarà, G | 1 |
| Fiordaliso, F | 1 |
| Calvillo, L | 1 |
| Bernasconi, R | 1 |
| Torri, M | 1 |
| Rondelli, I | 1 |
| Razzetti, R | 1 |
| Bongrani, S | 1 |
| Singh, JP | 1 |
| Musialek, P | 1 |
| Davey, P | 1 |
| Marinho, M | 1 |
| Hart, G | 1 |
| Feuerstein, G | 1 |
| Liu, GL | 1 |
| Yue, TL | 1 |
| Cheng, HY | 1 |
| Hieble, JP | 1 |
| Arch, JR | 1 |
| Ruffolo, RR | 1 |
| Ma, XL | 1 |
| Pieniazek, P | 1 |
| Dudek, D | 1 |
| Kocurek, A | 1 |
| Trebacz, J | 1 |
| Grodecki, J | 1 |
| Nozawa, T | 1 |
| Inoue, H | 1 |
| Dakik, HA | 1 |
| Kleiman, NS | 1 |
| Farmer, JA | 1 |
| He, ZX | 1 |
| Wendt, JA | 1 |
| Verani, MS | 1 |
| Mahmarian, JJ | 1 |
| Ludman, PF | 1 |
| Karlson, B | 2 |
| Coletta, C | 2 |
| Ricci, R | 2 |
| Ceci, V | 2 |
| Seccareccia, F | 1 |
| Rulli, F | 1 |
| Mazzuca, V | 1 |
| Putini, RL | 2 |
| Salustri, A | 2 |
| Bottero, G | 2 |
| Pasquale, M | 2 |
| Raviele, A | 1 |
| Bongiorni, MG | 1 |
| Brignole, M | 1 |
| Capucci, A | 1 |
| Gaita, F | 1 |
| Mangiameli, S | 1 |
| Montenero, A | 1 |
| Pedretti, R | 1 |
| Salerno, J | 1 |
| Sermasi, S | 1 |
| Peters, DH | 1 |
| Benfield, P | 2 |
| Gardtman, M | 1 |
| Brunnhage, C | 1 |
| Lindkvist, J | 1 |
| Waagstein, L | 1 |
| Sandèn, W | 1 |
| Svensson, H | 1 |
| Sjölin, M | 1 |
| Rochon, PA | 1 |
| Anderson, GM | 1 |
| Tu, JV | 1 |
| Gurwitz, JH | 1 |
| Clark, JP | 1 |
| Shear, NH | 1 |
| Lau, P | 1 |
| Poulsen, SH | 2 |
| Jensen, SE | 2 |
| Egstrup, K | 2 |
| Nicol, PD | 1 |
| Rogers, WJ | 3 |
| Seibel, PS | 1 |
| Park, CS | 1 |
| Reichek, N | 1 |
| Meyer, MI | 1 |
| Kuhn, M | 1 |
| Bühler, H | 1 |
| Bertschinger, P | 1 |
| Wagner, K | 1 |
| Kamkin, A | 1 |
| Kiseleva, I | 1 |
| Theres, H | 1 |
| Scholz, H | 1 |
| Günther, J | 2 |
| Währborg, P | 1 |
| Abdon, N | 1 |
| Mehrotra, DV | 2 |
| Railkar, R | 1 |
| Prabhu, SD | 1 |
| Chandrasekar, B | 1 |
| Murray, DR | 1 |
| Freeman, GL | 1 |
| Heldal, M | 1 |
| Sire, S | 1 |
| Dale, J | 1 |
| Ishikawa, K | 1 |
| Miyataka, M | 1 |
| Kanamasa, K | 1 |
| Hayashi, T | 1 |
| Takenaka, T | 1 |
| Inoki, T | 1 |
| Katayama, K | 1 |
| Kimura, A | 1 |
| Yabushita, H | 1 |
| Kitayama, K | 1 |
| Aronow, WS | 1 |
| Wei, S | 1 |
| Chow, LT | 1 |
| Sanderson, JE | 1 |
| Rifkin, W | 1 |
| Walerstein, S | 1 |
| Railkar, RA | 1 |
| Iglewicz, B | 1 |
| Rezig, K | 1 |
| Diar, N | 1 |
| Walcker, JL | 1 |
| Tjeerdsma, G | 1 |
| Szabó, BM | 1 |
| van Wijk, LM | 1 |
| Tio, RA | 1 |
| van Veldhuisen, DJ | 1 |
| Mobini, R | 1 |
| Madhu, B | 1 |
| Kujacic, V | 2 |
| Hjalmarson , A | 1 |
| Gottlieb, SS | 1 |
| McCarter, RJ | 1 |
| Theres, HP | 1 |
| Wagner, KD | 1 |
| Romberg, D | 1 |
| Feig, C | 1 |
| Strube, S | 1 |
| Leiterer, KP | 1 |
| Stangl, K | 1 |
| Schimke, I | 1 |
| Kovach, JA | 1 |
| Nearing, BD | 1 |
| Verrier, RL | 1 |
| Min, JY | 1 |
| Ding, B | 1 |
| Wang, JF | 1 |
| Sullivan, MF | 1 |
| Morgan, JP | 1 |
| Dickerson, LM | 1 |
| Carek, PJ | 1 |
| Haverkamp, W | 2 |
| Hindricks, G | 2 |
| Gülker, H | 2 |
| Pajes, G | 1 |
| Blackman, BT | 1 |
| Bergh, CH | 1 |
| Kjellström, C | 1 |
| Bengtsson, BA | 1 |
| Isgaard, J | 1 |
| Billinger, M | 1 |
| Seiler, C | 1 |
| Fleisch, M | 1 |
| Eberli, FR | 1 |
| Meier, B | 1 |
| Hess, OM | 1 |
| Andréasson, K | 1 |
| Tidgren, B | 1 |
| Hall, C | 1 |
| Ohte, N | 1 |
| Kurokawa, K | 1 |
| Iida, A | 1 |
| Narita, H | 1 |
| Akita, S | 1 |
| Yajima, K | 1 |
| Miyabe, H | 1 |
| Hayano, J | 1 |
| Kimura, G | 1 |
| Tekten, T | 1 |
| Ceyhan, C | 1 |
| Onbaşili, OA | 1 |
| Akilli, A | 1 |
| Türkoğlu, C | 1 |
| Mombay, B | 1 |
| Meinertz, T | 1 |
| Just, H | 1 |
| Kasper, W | 1 |
| Kersting, F | 1 |
| Breuing, KH | 1 |
| Hjalmarson, AC | 2 |
| Dominiak, P | 1 |
| Sebening, H | 1 |
| Grobecker, H | 1 |
| Sack, D | 1 |
| Scognamiglio, R | 1 |
| Nistri, S | 1 |
| Fasoli, G | 1 |
| Frigato, N | 1 |
| Miorelli, M | 1 |
| Karavidas, A | 1 |
| Ponchia, A | 1 |
| Dalla-Volta, S | 1 |
| Meluzín, J | 1 |
| Stejfa, M | 1 |
| Novák, M | 1 |
| Zeman, K | 1 |
| Spinarová, L | 1 |
| Julínek, J | 1 |
| Toman, J | 1 |
| Simek, P | 1 |
| Bergelson, BA | 1 |
| Jacobs, AK | 2 |
| Faxon, DP | 2 |
| Rønnevik, PK | 2 |
| von der Lippe, G | 1 |
| Willich, SN | 1 |
| Arntz, HR | 1 |
| Löwel, H | 1 |
| Lewis, M | 1 |
| Schröder, R | 1 |
| Warnold, I | 2 |
| Manger Cats, V | 1 |
| McBoyle, D | 1 |
| Sonneblick, EH | 1 |
| Green, BK | 1 |
| Gordon, GD | 1 |
| Horak, AR | 1 |
| Millar, RN | 1 |
| Commerford, PJ | 1 |
| Sigurdsson, A | 1 |
| Held, P | 2 |
| Andersson, G | 1 |
| Mueller, HS | 1 |
| Lambrew, CT | 2 |
| Diver, DJ | 1 |
| Smith, HC | 1 |
| Knatterud, GL | 1 |
| Forman, S | 1 |
| Passamani, E | 1 |
| Rapaport, E | 1 |
| Tuomilehto, J | 1 |
| Berglund, G | 1 |
| Risenfors, M | 1 |
| Berg, CH | 1 |
| Gustavsson, G | 1 |
| Gottfridsson, C | 1 |
| Lomsky, M | 2 |
| Hjalmarsson, A | 1 |
| Babb, JD | 1 |
| Baim, DS | 1 |
| Chesebro, JH | 1 |
| Gore, JM | 2 |
| Williams, DO | 1 |
| Frederick, M | 2 |
| Passamani, ER | 1 |
| Hancock, EW | 1 |
| Bovill, EG | 1 |
| Terrin, ML | 1 |
| Stump, DC | 1 |
| Berke, AD | 1 |
| Collen, D | 2 |
| Feit, F | 1 |
| Kronenberg, MW | 2 |
| Beard, JT | 1 |
| Stein, SM | 1 |
| Sandler, MP | 1 |
| Verheugt, FW | 1 |
| Martins, JB | 2 |
| Clothier, JL | 1 |
| Marcus, ML | 1 |
| Jang, IK | 3 |
| van de Werf, F | 3 |
| Aubert, A | 1 |
| Blake, GJ | 1 |
| Kock, M | 1 |
| Blomberg, S | 2 |
| Strömblad, SO | 1 |
| Ricksten, SE | 2 |
| Jonas, S | 1 |
| Bekheit, S | 1 |
| Tangella, M | 1 |
| el-Sakr, A | 1 |
| Rasheed, Q | 1 |
| Craelius, W | 1 |
| el-Sherif, N | 1 |
| Kirby, DA | 1 |
| Hottinger, S | 1 |
| Ravid, S | 1 |
| Lown, B | 1 |
| Murray, DP | 5 |
| Murray, RG | 4 |
| Littler, WA | 4 |
| Steinbeck, G | 1 |
| Andresen, D | 1 |
| von Leitner, ER | 1 |
| Hartwig, CA | 1 |
| Bethge, KP | 1 |
| Wenzlaff, P | 1 |
| Lichtlen, PR | 1 |
| Tijssen, JG | 4 |
| Linnik, W | 1 |
| Tintinalli, JE | 1 |
| Ramos, R | 1 |
| Steingart, RM | 1 |
| Matthews, R | 1 |
| Gambino, A | 1 |
| Kantrowitz, N | 1 |
| Katz, S | 1 |
| Bestetti, RB | 1 |
| Pinto, LZ | 1 |
| Finzi, LA | 1 |
| Secches, AL | 1 |
| Hauptlorenz, S | 1 |
| Puschendorf, B | 1 |
| Wencker, M | 1 |
| Dienstl, F | 1 |
| Gundersen, T | 1 |
| Abrahamsen, AM | 1 |
| Knutsen, H | 1 |
| Woie, L | 1 |
| Antman, EM | 1 |
| Dupont, WD | 1 |
| Bonalsky, J | 1 |
| Califf, RM | 1 |
| Corwin, S | 1 |
| Fink, L | 1 |
| Hansen, DE | 1 |
| Kawanishi, DT | 1 |
| McKay, CR | 1 |
| Malmberg, K | 1 |
| Halinen, MO | 1 |
| Palomäki, P | 1 |
| Kuikka, J | 1 |
| Länsimies, E | 1 |
| Miettinen, H | 1 |
| Penttilä, I | 1 |
| Pyörälä, K | 1 |
| Wiklund, I | 2 |
| Breisblatt, WM | 1 |
| Waldo, DA | 1 |
| Burns, MJ | 1 |
| Spaccavento, LJ | 1 |
| Fletcher, GF | 1 |
| Halawa, B | 1 |
| Mazurek, W | 1 |
| Nanas, JN | 1 |
| Sutton, RB | 1 |
| Alazraki, N | 1 |
| Tsagaris, TJ | 1 |
| Wallentin, L | 1 |
| Algra, A | 1 |
| Roelandt, JR | 1 |
| Simoons, ML | 2 |
| Pool, J | 1 |
| Vlay, SC | 1 |
| Lawson, WE | 1 |
| Ekman, AM | 2 |
| Walsh, RA | 1 |
| Clissold, SP | 1 |
| Brogden, RN | 1 |
| Bengtson, A | 3 |
| Rafiqi, E | 2 |
| Renard, M | 1 |
| Jacobs, P | 1 |
| Liebens, I | 1 |
| Abou Hamdam, B | 1 |
| Bernard, R | 1 |
| van Es, GA | 1 |
| Appleby, JL | 1 |
| Levin, LA | 2 |
| Melandri, G | 1 |
| Branzi, A | 1 |
| Tartagni, F | 1 |
| Berardi, C | 1 |
| Bruscoli, F | 1 |
| Rubino, I | 1 |
| Magnani, B | 1 |
| Braksator, W | 1 |
| Kuch, J | 1 |
| Szczepańczyk, E | 1 |
| Mamcarz, A | 1 |
| Vassanelli, C | 1 |
| Menegatti, G | 1 |
| Nidasio, GP | 1 |
| Franceschini, L | 1 |
| Cocco, C | 1 |
| Rizzotti, P | 1 |
| Freyschuss, U | 1 |
| Zetterquist, S | 1 |
| Samuelsson, SO | 1 |
| Richter, A | 2 |
| Ades, PA | 1 |
| Thomas, JD | 1 |
| Hanson, JS | 1 |
| Shapiro, SM | 1 |
| LaMountain, J | 1 |
| Kerkkamp, HJ | 2 |
| Viersma, JW | 1 |
| de Beijer, JM | 1 |
| de Feijter, PJ | 1 |
| Watson, RD | 1 |
| Zezulka, AV | 1 |
| Odén, A | 1 |
| Johansson, L | 1 |
| Thale, J | 1 |
| Held, PH | 4 |
| Sillfors, L | 1 |
| Lindvall, K | 1 |
| Rössner, S | 1 |
| Pasternack, PF | 1 |
| Imparato, AM | 1 |
| Baumann, FG | 1 |
| Laub, G | 1 |
| Riles, TS | 1 |
| Lamparello, PJ | 1 |
| Grossi, EA | 1 |
| Berguson, P | 1 |
| Becker, G | 1 |
| Bear, G | 1 |
| Corbeij, HM | 2 |
| Dunselman, PH | 1 |
| Denniss, AR | 1 |
| Ross, DL | 1 |
| Richards, DA | 1 |
| Cody, DV | 1 |
| Russell, PA | 1 |
| Young, AA | 1 |
| Uther, JB | 1 |
| Regårdh, CG | 1 |
| Constantin, L | 1 |
| Vilén, L | 1 |
| Kutti, J | 1 |
| Hauer, B | 1 |
| Grison, D | 1 |
| Favier, JP | 1 |
| Sacrez, A | 1 |
| van der Wall, EE | 1 |
| van Rijk, PP | 1 |
| Reiber, JH | 1 |
| Bom, N | 1 |
| Roos, JP | 1 |
| Nicholas, J | 1 |
| Dunselman, P | 1 |
| Murray, D | 1 |
| Dłuzniewski, M | 1 |
| Jurgiel, R | 1 |
| Budaj, A | 1 |
| Ashburn, RW | 1 |
| Savage, RW | 1 |
| Jacob, AS | 1 |
| Lindsay, J | 1 |
| Bullock, GR | 1 |
| Leprán, I | 1 |
| Parratt, JR | 1 |
| Szekeres, L | 1 |
| Wainwright, CL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| "Effect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion. The MEEffect of METOprolol in CARDioproteCtioN During an Acute Myocardial InfarCtion (METOCARD-CNIC): A Randomized, Controlled Parallel-group, Observer-blinded Clinical Trial[NCT01311700] | Phase 4 | 221 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
| Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial Infarction: a Double-Blind, Multicenter, Randomized, Placebo-Controlled Clinical Trial[NCT04912518] | 250 participants (Anticipated) | Interventional | 2021-05-27 | Recruiting | |||
| ASSessing the Effect of Anti-IL-6 Treatment in Myocardial Infarction: The ASSAIL-MI Trial[NCT03004703] | Phase 2 | 200 participants (Actual) | Interventional | 2017-03-16 | Completed | ||
| Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After ST-elevation Myocardial Infarction[NCT03516903] | Phase 2/Phase 3 | 35 participants (Actual) | Interventional | 2018-04-17 | Terminated (stopped due to Due to the COVID-19 pandemic. With a second wave just beginning, and considering that we are testing an immunosuppressant in patients with high risk for COVID-19 complications, we would not be able to re-start recruitment safely in the near future.) | ||
| Pharmacogenetic Study of Bisoprolol in Egyptian Patients With Acute Coronary Syndrome[NCT05536271] | Phase 2 | 127 participants (Actual) | Interventional | 2021-09-01 | Completed | ||
| Potential Drug Interactions With Bisoprolol in Egyptian Patients With Acute Coronary Syndrome[NCT05536284] | Phase 2 | 128 participants (Actual) | Interventional | 2021-09-01 | Completed | ||
| Brasilia Heart Study of Outcome Markers in ST-elevation Myocardial Infarction[NCT02062554] | 1,000 participants (Anticipated) | Observational [Patient Registry] | 2006-05-31 | Recruiting | |||
| Effect of Ivabradine, Carvedilol or Their Combination in Patients With Heart Failure[NCT01178528] | Phase 3 | 121 participants (Actual) | Interventional | 2009-09-30 | Completed | ||
| Efficacy and Safety on Heart Rate Control With Ivabradine on Cardiogenic Shock (ES-FISH)[NCT03437369] | Phase 4 | 22 participants (Anticipated) | Interventional | 2018-05-31 | Not yet recruiting | ||
| The PACE-MI Registry Study - Outcomes of Beta-blocker Therapy After Myocardial Infarction (OBTAIN)[NCT00430612] | 7,057 participants (Actual) | Observational [Patient Registry] | 2009-05-31 | Completed | |||
| A Study of (R, R') and (S,S': R,R')- Fenoterol: Initial Clinical Evaluation for Pharmacokinetics, Pharmacodynamics, and Safety[NCT01440335] | Phase 1 | 29 participants (Actual) | Interventional | 2011-07-10 | Completed | ||
| Clopidogrel Or Metoprolol in Myocardial Infarction Trial[NCT00222573] | Phase 4 | 46,000 participants | Interventional | 1999-07-31 | Completed | ||
| aMsa and amiOdarone Study in cArdiaC Arrest[NCT04997980] | 500 participants (Anticipated) | Observational | 2015-01-01 | Recruiting | |||
| [NCT00257959] | Phase 4 | 400 participants | Interventional | 2001-01-31 | Completed | ||
| Perioperative Ischemic Evaluation Study (POISE) Trial[NCT00182039] | Phase 3 | 8,351 participants (Actual) | Interventional | 2002-10-31 | Terminated (stopped due to Please see detailed description for reason why study was terminated.) | ||
| A Randomized Controlled Trial of Influenza Vaccine to Prevent Adverse Vascular Events: A Pilot Study[NCT01945268] | Phase 4 | 107 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| A Randomized Controlled Trial of Influenza Vaccine to Prevent Adverse Vascular Events[NCT02762851] | Phase 4 | 5,000 participants (Anticipated) | Interventional | 2016-06-30 | Recruiting | ||
| A Single Centre, Retrospective Cohort Study on Post Analysis on the Link Between the Clinical Heart Rate and Outcomes During PCI[NCT02351674] | 15,000 participants (Anticipated) | Observational | 2015-01-31 | Not yet recruiting | |||
| Heart Rate Lowering Efficacy and Respiratory Safety of Ivabradine in Patients With Obstructive Airway Disease[NCT01365286] | Phase 4 | 40 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| [NCT00000505] | Phase 3 | 0 participants | Interventional | 1983-04-30 | Completed | ||
| Verapamil as Adjunctive Seizure Therapy for Children and Young Adults With Dravet Syndrome[NCT01607073] | Phase 2 | 2 participants (Actual) | Interventional | 2012-04-30 | Completed | ||
| Patients Presenting With Acute STEMI Treated With Primary PCI : Comparison of the Impact of the MIMI Approach With a Conventional Strategy of Immediate Stenting[NCT01360242] | Phase 3 | 160 participants (Actual) | Interventional | 2011-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Distance measured at 6 minute walking test. The 6 minute walking test was performed according to standardised procedure at baseline, before inclusion (at least 1 week after baseline evaluation), and at the end of the study. Patients who had not done at least two tests in the past underwent two practice 6 minute walking tests at least 3 days apart. Results are expressed in terms of distance walked (metres). The test was supervised by a physical therapist.~Patients were asked to walk at their own maximal pace a 100 m long hospital corridor. At the beginning of the last (6th) minute of the test a standard phrase of encouragement was told. Patients were allowed to stop if signs or symptoms of significant distress occurred (dyspnea, angina), through they were instructed to resume walking as soon as possible." (NCT01178528)
Timeframe: 3 months
| Intervention | meters (Mean) |
|---|---|
| Ivabradine | 474.8 |
| Carvedilol | 435.7 |
| Carvedilol and Ivabradine | 453.1 |
Functional capacity was assessed by means of a cardiopulmonary exercise test with a bicycle ergometer with gas exchange monitoring (Vmax 29 C, SensorMedics). Peak oxygen consumption was defined as the maximal oxygen consumption (MVO2) observed during exercise. (NCT01178528)
Timeframe: 3 months
| Intervention | mL/Kg/min (Mean) |
|---|---|
| Ivabradine | 15.8 |
| Carvedilol | 12.9 |
| Carvedilol and Ivabradine | 14.7 |
"The 1994 NYHA Classification system is a measure of functional status. It was designed for clinical assessment of patients by physicians as NYHA class I, II, III, or IV, on the basis of patient's limitations in physical activities caused by cardiac symptoms.~Class I describes patients with cardiovascular disease (CVD) but without resulting limitation of physical activity. There is no objective evidence of CVD.~Class II describes patients with CVD resulting in slight limitation of physical activity. There is objective evidence of minimal CVD.~Class III describes patients with CVD resulting in marked limitation of physical activity. There is objective evidence of moderately severe CVD.~Class IV describes patients with CVD resulting in inability to carry on any physical activity without discomfort. There is objective evidence of severe CVD.~Here we report data on number of patients showing an improvement by at least one NYHA class according to treatment allocation." (NCT01178528)
Timeframe: 3 months
| Intervention | participants (Number) |
|---|---|
| Ivabradine | 30 |
| Carvedilol | 5 |
| Carvedilol and Ivabradine | 20 |
Quality of life (QoL) was evaluated using the Visual Analogue Scale (VAS) which is a global measurement of QoL, allowing a subjective assessment of the impact of the disease and treatment. Patients are asked to indicate their current state in a line from 0 (worst state) to 10 (best state), with higher values therefore representing a better outcome. (NCT01178528)
Timeframe: 3 months
| Intervention | units on a scale (Mean) |
|---|---|
| Ivabradine | 6.7 |
| Carvedilol | 4.1 |
| Carvedilol and Ivabradine | 6.1 |
The secondary outcome measure is the change in number of absence seizures from Week 8 (Baseline) to Week 12 (NCT01607073)
Timeframe: Week 8 to Week 12
| Intervention | Abscence seizures (Number) |
|---|---|
| Week 8 Baseline | 165 |
| Week 12 Verapamil 4mg/kg/Day | 101 |
The primary study endpoint is the change in number of seizures from baseline. Since we only had one participant finish the study, the endpoint was changed to Week 12 visit. Participants were on verapamil for 4 weeks at Week 12. (NCT01607073)
Timeframe: Week 8 (baseline) to Week 12
| Intervention | General tonic-clonic seizures (Number) |
|---|---|
| Week 8 Baseline | 39 |
| Week 12 Verapamil 4mg/kg/Day | 14 |
The secondary outcome is the change in number of myoclonic seizures between baseline Week 8 visit and Week 12 visit. (NCT01607073)
Timeframe: Week 8 (baseline) to Week 12
| Intervention | Myoclonic seizures (Number) |
|---|---|
| Week 8 Baseline | 116 |
| Week 12 Verapamil 4mg/kg/Day | 175 |
39 reviews available for metoprolol and Cardiovascular Stroke
| Article | Year |
|---|---|
Effect of early metoprolol before PCI in ST-segment elevation myocardial infarction on infarct size and left ventricular ejection fraction. A systematic review and meta-analysis of clinical trials.
Topics: Humans; Metoprolol; Myocardial Infarction; Percutaneous Coronary Intervention; ST Elevation Myocardi | 2022 |
Should We Be Using Upstream Beta-Blocker Therapy for Acute Myocardial Infarction?
Topics: Adrenergic beta-Antagonists; Humans; Metoprolol; Myocardial Infarction; Percutaneous Coronary Interv | 2021 |
Meta-Analysis Comparing Metoprolol and Carvedilol on Mortality Benefits in Patients With Acute Myocardial Infarction.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Aged; Carbazoles; C | 2017 |
Editor's Choice- Pathophysiology and therapy of myocardial ischaemia/reperfusion syndrome.
Topics: Acetylcysteine; Acute Disease; Administration, Intravenous; Adrenergic beta-1 Receptor Antagonists; | 2019 |
[Perioperative cardiovascular evaluation and management for noncardiac surgery].
Topics: Adrenergic beta-Antagonists; Anesthesia; Atenolol; Bisoprolol; Fatty Acids, Monounsaturated; Fluvast | 2014 |
Is there still a role for treatment with beta-adrenoceptor antagonists in post-myocardial infarction patients with well-preserved left ventricular systolic function?
Topics: Adrenergic Antagonists; Angioplasty, Balloon, Coronary; Endothelium, Vascular; Humans; Metoprolol; M | 2008 |
[The POISE study].
Topics: Adrenergic beta-Antagonists; Bradycardia; Delayed-Action Preparations; Heart Arrest; Humans; Hyperte | 2008 |
Influence of beta-blockers on the outcome of at risk patients.
Topics: Adrenergic beta-Antagonists; Cohort Studies; Contraindications; Coronary Disease; Double-Blind Metho | 2009 |
Cardioprotective effects of perioperative β-blockade in vascular surgery patients: fact or fiction?
Topics: Adrenergic beta-Antagonists; Humans; Meta-Analysis as Topic; Metoprolol; Myocardial Infarction; Peri | 2011 |
[Modulation of the beta-adrenergic system during acute myocardial infarction: rationale for a new clinical trial].
Topics: Acute Disease; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Clinical Trials | 2011 |
Carvedilol: a third-generation β-blocker should be a first-choice β-blocker.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Atenolol; Biomarkers; Carbazoles; Car | 2012 |
Beta blocker use after acute myocardial infarction in the patient with normal systolic function: when is it "ok" to discontinue?
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Contraindications; Humans; Metoprolol; Myocar | 2012 |
Meta-analysis of carvedilol versus beta 1 selective beta-blockers (atenolol, bisoprolol, metoprolol, and nebivolol).
Topics: Adrenergic beta-1 Receptor Antagonists; Atenolol; Benzopyrans; Bisoprolol; Carbazoles; Carvedilol; E | 2013 |
Beta-blockers and diabetes: the bad guys come good.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Bisoprolol; Coronary Disease; Diabet | 2002 |
Use of beta-blockers in older adults with chronic heart failure.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Cardiovascu | 2004 |
A review of carvedilol arrhythmia data in clinical trials.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprolol; Ca | 2005 |
Carvedilol: use in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol; Diabe | 2007 |
Dynamic left ventricular outflow tract obstruction in acute myocardial infarction with shock: cause, effect, and coincidence.
Topics: Adrenergic beta-Antagonists; Aged; Algorithms; Amiodarone; Cardiac Catheterization; Diagnosis, Diffe | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Resting heart rate in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Carbazoles; Ca | 2007 |
Switching to once-daily evidence-based [beta]-blockers in patients with systolic heart failure or left ventricular dysfunction after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Algorithms; Carbazoles; Carvedilol; Delayed-Action Preparations; Eviden | 2007 |
Beta blocking agents: current status in the prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary D | 1982 |
Comparative review of beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Atenolol; Humans; Hypertension; | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans | 1984 |
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial In | 1984 |
Early intervention with a beta-blocking drug after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Pr | 1984 |
Short- and long-term influence of beta-adrenergic antagonists after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Clinical Trials as Topic; Coronary Disease; Do | 1984 |
The role of beta-adrenergic receptor antagonists in the prevention of sudden cardiac death.
Topics: Action Potentials; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Calcium; Calcium Channel Block | 1984 |
[Exertion hypertension in coronary disease and its importance in prevention and rehabilitation].
Topics: Adult; Coronary Disease; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Metoprolol; Middle | 1982 |
[Treatment with beta-blockers in patients with acute coronary syndrome].
Topics: Acute Disease; Adrenergic beta-Antagonists; Angina, Unstable; Atenolol; Clinical Trials as Topic; Co | 1998 |
Metoprolol: a pharmacoeconomic and quality-of-life evaluation of its use in hypertension, post-myocardial infarction and dilated cardiomyopathy.
Topics: Cardiomyopathy, Dilated; Cost of Illness; Cost-Benefit Analysis; Economics, Pharmaceutical; Follow-U | 1994 |
Beta-blockers, angiotensin-converting enzyme inhibitors, and calcium antagonists in treatment of elderly patients with acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Hum | 2000 |
Antiarrhythmic properties of beta-blockers.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Bisoprolol; Humans; Metoprolol; Myocar | 1990 |
Primary prevention with beta-blockade in patients with hypertension: review of results and clinical implications.
Topics: Adrenergic beta-Antagonists; Atenolol; Benzothiadiazines; Clinical Trials as Topic; Data Interpretat | 1990 |
Reversible and irreversible left ventricular dysfunction after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Echocardiography; Humans; Metoprolol; Myocar | 1992 |
Metoprolol-induced reduction in postinfarction mortality: pooled results from five double-blind randomized trials.
Topics: Double-Blind Method; Female; Humans; Male; Meta-Analysis as Topic; Metoprolol; Myocardial Infarction | 1992 |
[Intervention with beta-blockers in acute myocardial infarct].
Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Fibrinolytic Agents; Humans; Metoprolol; Myo | 1990 |
Use of beta adrenoceptor blockade during and after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Atenolol; Cardiotonic Agents; Clinical Trials as | 1986 |
[Effect of beta-adrenolytic drugs on the survival of patients after myocardial infarction].
Topics: Adrenergic beta-Antagonists; Adult; Aftercare; Aged; Clinical Trials as Topic; Follow-Up Studies; Hu | 1986 |
Metoprolol. An updated review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in hypertension, ischaemic heart disease and related cardiovascular disorders.
Topics: Adult; Age Factors; Aged; Arrhythmias, Cardiac; Cardiomegaly; Coronary Disease; Drug Interactions; D | 1986 |
207 trials available for metoprolol and Cardiovascular Stroke
| Article | Year |
|---|---|
No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Göttingen minipigs.
Topics: Animals; Metoprolol; Myocardial Infarction; Myocardial Ischemia; Myocardium; Swine; Swine, Miniature | 2023 |
Coexistence of transmural and lateral wavefront progression of myocardial infarction in the human heart.
Topics: Contrast Media; Gadolinium; Humans; Metoprolol; Myocardial Infarction; ST Elevation Myocardial Infar | 2021 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
Effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) tri
Topics: Adrenergic beta-Antagonists; Biomarkers; Cardiotonic Agents; Combined Modality Therapy; Creatine Kin | 2013 |
A pharmacokinetic and pharmacodynamic comparison of immediate-release metoprolol and extended-release metoprolol CR/XL in patients with suspected acute myocardial infarction: a randomized, open-label study.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Analysis of Varia | 2014 |
Long-term benefit of early pre-reperfusion metoprolol administration in patients with acute myocardial infarction: results from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction).
Topics: Adrenergic beta-1 Receptor Antagonists; Early Medical Intervention; Humans; Metoprolol; Middle Aged; | 2014 |
Long-term benefit of early pre-reperfusion metoprolol administration in patients with acute myocardial infarction: results from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction).
Topics: Adrenergic beta-1 Receptor Antagonists; Early Medical Intervention; Humans; Metoprolol; Middle Aged; | 2014 |
Long-term benefit of early pre-reperfusion metoprolol administration in patients with acute myocardial infarction: results from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction).
Topics: Adrenergic beta-1 Receptor Antagonists; Early Medical Intervention; Humans; Metoprolol; Middle Aged; | 2014 |
Long-term benefit of early pre-reperfusion metoprolol administration in patients with acute myocardial infarction: results from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction).
Topics: Adrenergic beta-1 Receptor Antagonists; Early Medical Intervention; Humans; Metoprolol; Middle Aged; | 2014 |
Efficacy and safety of out-of-hospital intravenous metoprolol administration in anterior ST-segment elevation acute myocardial infarction: insights from the METOCARD-CNIC trial.
Topics: Adrenergic beta-1 Receptor Antagonists; Emergency Medical Services; Female; Humans; Injections, Intr | 2015 |
Rationale and design of a double-blind, multicenter, randomized, placebo-controlled clinical trial of early administration of intravenous β-blockers in patients with ST-elevation myocardial infarction before primary percutaneous coronary intervention: EAR
Topics: Administration, Intravenous; Adrenergic beta-Antagonists; Combined Modality Therapy; Double-Blind Me | 2014 |
Impact of Carvedilol versus β1-selective β blockers (bisoprolol, metoprolol, and nebivolol) in patients with acute myocardial infarction undergoing percutaneous coronary intervention.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagonists; Bisoprolol; Carbazo | 2015 |
CYP2D6 is a major determinant of metoprolol disposition and effects in hospitalized Russian patients treated for acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Area Under Curve; Chromatography, High | 2008 |
[Effects of metoprolol on perioperative cardiovascular events in patients with risk or at high risk for coronary artery disease undergoing non-cardiac surgery].
Topics: Aged; Cardiovascular Diseases; Coronary Artery Disease; Female; Humans; Male; Metoprolol; Myocardial | 2008 |
Effect of beta blockers (metoprolol or propranolol) on effect of simvastatin in lowering C-reactive protein in acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; C-Reactive Protein; Cohort Studies; Drug Therapy, Combination; Fe | 2009 |
Long-term stability of heart rate variability in chronic stable angina pectoris, and the impact of an acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Coron | 2009 |
Comparison of ivabradine versus metoprolol in early phases of reperfused anterior myocardial infarction with impaired left ventricular function: preliminary findings.
Topics: Aged; Benzazepines; Double-Blind Method; Female; Follow-Up Studies; Humans; Ivabradine; Male; Metopr | 2009 |
Comparison of ivabradine versus metoprolol in early phases of reperfused anterior myocardial infarction with impaired left ventricular function: preliminary findings.
Topics: Aged; Benzazepines; Double-Blind Method; Female; Follow-Up Studies; Humans; Ivabradine; Male; Metopr | 2009 |
Comparison of ivabradine versus metoprolol in early phases of reperfused anterior myocardial infarction with impaired left ventricular function: preliminary findings.
Topics: Aged; Benzazepines; Double-Blind Method; Female; Follow-Up Studies; Humans; Ivabradine; Male; Metopr | 2009 |
Comparison of ivabradine versus metoprolol in early phases of reperfused anterior myocardial infarction with impaired left ventricular function: preliminary findings.
Topics: Aged; Benzazepines; Double-Blind Method; Female; Follow-Up Studies; Humans; Ivabradine; Male; Metopr | 2009 |
Risk prediction in stable angina pectoris.
Topics: Aged; Angina, Stable; Anti-Arrhythmia Agents; Blood Glucose; Creatinine; Double-Blind Method; Female | 2013 |
Dose of metoprolol CR/XL and clinical outcomes in patients with heart failure: analysis of the experience in metoprolol CR/XL randomized intervention trial in chronic heart failure (MERIT-HF).
Topics: Adrenergic beta-Antagonists; Aged; Chronic Disease; Dose-Response Relationship, Drug; Female; Follow | 2002 |
Metoprolol CR/XL in postmyocardial infarction patients with chronic heart failure: experiences from MERIT-HF.
Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Coronary Artery Bypass; Double-Bl | 2003 |
Response to programmed ventricular stimulation and clinical outcome in cardiac arrest survivors receiving randomised assignment to implantable cardioverter defibrillator or antiarrhythmic drug therapy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Electrophysiologic Techniques, Card | 2004 |
Carvedilol versus metoprolol in patients undergoing direct percutaneous coronary interventions for myocardial infarction: effects on QT dynamicity.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Carbazole | 2005 |
Carvedilol versus metoprolol in the acute phase of myocardial infarction:.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Carbazoles; Carvedilol; Female; Heart R | 2005 |
Effects of metoprolol and carvedilol on cause-specific mortality and morbidity in patients with chronic heart failure--COMET.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Double-Blind Method; Fe | 2005 |
[Antiischemic and metabolic effects of nebivolol and metaprolol CR/XL (betalok ZOK) in patients with postinfarction heart dysfunction].
Topics: Adrenergic beta-Antagonists; Benzopyrans; Blood Glucose; Coronary Angiography; Coronary Circulation; | 2005 |
Favourable long term prognosis in stable angina pectoris: an extended follow up of the angina prognosis study in Stockholm (APSIS).
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Death, Sudden, Cardiac; Diab | 2006 |
Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; China; Drug Administration Schedule; Female | 2005 |
Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; China; Drug Administration Schedule; Female | 2005 |
Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; China; Drug Administration Schedule; Female | 2005 |
Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; China; Drug Administration Schedule; Female | 2005 |
Effects of metoprolol therapy on cardiac troponin-I levels after elective percutaneous coronary interventions.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Blood Pressure; C | 2006 |
Comparison of carvedilol and metoprolol in patients with acute myocardial infarction undergoing primary coronary intervention--the PASSAT Study.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Carbazoles; Carve | 2006 |
After myocardial infarction carvedilol improves insulin resistance compared to metoprolol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; C-Peptide; Carbazoles; Carve | 2006 |
[Therapy of acute mayocardial infarction: COMMIT (Clopidogrel and Metoprolol Infarction Trial)].
Topics: Administration, Oral; Antihypertensive Agents; China; Clopidogrel; Drug Combinations; Humans; Metopr | 2006 |
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial.
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprol | 2006 |
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial.
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprol | 2006 |
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial.
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprol | 2006 |
Effect of amiodarone and sotalol on ventricular defibrillation threshold: the optimal pharmacological therapy in cardioverter defibrillator patients (OPTIC) trial.
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bisoprol | 2006 |
[Estimation of effectiveness of the prevention of sudden cardiac death in patients with myocardial infarction].
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Female; Humans; Male; M | 2006 |
Prognostic implications of renal dysfunction in patients with stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Disease | 2006 |
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl | 2007 |
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl | 2007 |
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl | 2007 |
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl | 2007 |
[Effect of low doses of metoprolol, bisoprolol and carvedilol on mortality in patients with left ventricular dysfunction after acute myocardial infarction].
Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Aged; Angioplasty, Balloon, Coronary; Bisoprolol; | 2006 |
[Assessment of dynamics of the autonomic cardiovascular system regulation based on low-frequency rhythm synchronization in patients with ischemic heart diseases complicated by myocardial infarction treated with metoprolol].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Autonomic Nervous System; Coronary Circulation; Electrocar | 2007 |
Randomized active-controlled study comparing effects of treatment with carvedilol versus metoprolol in patients with left ventricular dysfunction after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Cause of Death; Disease-Free Survival; Female; | 2007 |
Carvedilol increases copper-zinc superoxide dismutase activity in patients with acute myocardial infarction.
Topics: Adrenergic Antagonists; Carbazoles; Carvedilol; Drug Therapy, Combination; Erythrocytes; Female; Fre | 2007 |
[The effects of beta-adrenoblocker therapy on the physical working capacity of patients with chronic heart failure of various origin].
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; | 2007 |
Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI).
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Area | 2008 |
Established beta-adrenergic receptor blocking therapy and acute myocardial infarction. A clinical study of risks and benefits.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Arrhythmias, Cardiac; Clinical Trials as Topic; Femal | 1980 |
Effect on mortality of metoprolol in acute myocardial infarction. A double-blind randomised trial.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; | 1981 |
Beta blocking agents: current status in the prevention of sudden coronary death.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Atenolol; Clinical Trials as Topic; Coronary D | 1982 |
Forum: beta-adrenoreceptor blockade after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Death, Sudden; Humans; Metoprolol; Myocardial | 1982 |
beta-Blockers and myocardial infarction.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Clinical Trials as Topic; Death, Sudden; Diuretic | 1982 |
Postinfarction therapy with beta blockers: who should be treated?
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Heart; Human | 1982 |
Secondary prevention with beta-adrenoceptor blockers in post-myocardial infarction patients.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Metoprolol; Myoc | 1982 |
Beta-adrenergic blocking agents after myocardial infarction: an undocumented need in patients at lowest risk.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Pr | 1983 |
Beta blockers in ischemic heart disease.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Humans | 1983 |
Chronic beta blockade therapy in patients after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Alprenolol; Clinical Trials as Topic; Double-Blind Method; Humans | 1983 |
[Use of adrenergic beta blockaders after myocardial infarction].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Pr | 1983 |
[Beta receptor blockers and calcium antagonists in coronary disease. Differential therapeutic aspects].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blocke | 1983 |
[Improved prognosis using beta blockers after myocardial infarct?].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Metoprolol | 1984 |
Prophylactic use of beta-adrenergic blockade in survivors of myocardial infarction.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Death, Sudden; Humans; Metoprolol; Myocardial | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans | 1984 |
[Therapeutic value of the long-term administration of beta-adrenergic blockaders after myocardial infarct].
Topics: Adrenergic beta-Antagonists; Alprenolol; Clinical Trials as Topic; Humans; Metoprolol; Myocardial In | 1984 |
Early intervention with a beta-blocking drug after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Humans; Metoprolol; Myocardial Infarction; Pr | 1984 |
Short- and long-term influence of beta-adrenergic antagonists after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Catecholamines; Clinical Trials as Topic; Coronary Disease; Do | 1984 |
Effect of very early intervention with metoprolol on myocardial infarct size.
Topics: Aged; Clinical Trials as Topic; Creatine Kinase; Double-Blind Method; Female; Humans; Isoenzymes; Ma | 1983 |
Effect of metoprolol on indirect signs of the size and severity of acute myocardial infarction.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Humans; L-Lactate | 1983 |
The Göteborg metoprolol trial. Effects on mortality and morbidity in acute myocardial infarction.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle | 1983 |
Beta-adrenoreceptor blocking agents. Their role in reducing chances of recurrent infarction and death.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Inf | 1983 |
Acute myocardial ischaemia: what information can be expected in the near future from ongoing clinical trials with nifedipine?
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Electrocardiography; Humans; Metoprolol | 1983 |
Effect of metoprolol on chest pain in acute myocardial infarction.
Topics: Adult; Aged; Analgesics; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Heart Rate; | 1984 |
Ventricular arrhythmias during the first year after acute myocardial infarction: influence of long-term treatment with metoprolol.
Topics: Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Fema | 1984 |
Development of congestive heart failure after treatment with metoprolol in acute myocardial infarction.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Furosemide; Heart Failure; Humans; Metop | 1984 |
Relationship between infarct size and incidence of severe ventricular arrhythmias in a double-blind trial with metoprolol in acute myocardial infarction.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; L-Lactate Dehydrogenase; | 1984 |
Hemodynamic and clinical findings after combined therapy with metoprolol and nifedipine in acute myocardial infarction.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combinatio | 1984 |
Enzymatically and electrocardiographically estimated infarct size in relation to pain in acute myocardial infarction.
Topics: Adult; Aged; Analgesics; Clinical Trials as Topic; Electrocardiography; Humans; L-Lactate Dehydrogen | 1984 |
Relationship between enzymatically estimated infarct size and short- and long-term survival after acute myocardial infarction.
Topics: Adult; Aged; Clinical Trials as Topic; Creatine Kinase; Double-Blind Method; Humans; Isoenzymes; L-L | 1984 |
Relationship between electrocardiographically and enzymatically estimated size in anterior myocardial infarction.
Topics: Adult; Aged; Clinical Enzyme Tests; Clinical Trials as Topic; Double-Blind Method; Electrocardiograp | 1984 |
Correlation between enzymatic estimation of infarct size and early mortality rate.
Topics: Adult; Aged; Creatine Kinase; Humans; Isoenzymes; L-Lactate Dehydrogenase; Metoprolol; Middle Aged; | 1983 |
A pharmacokinetic and platelet function study of the combined administration of metoprolol and sulfinpyrazone to healthy volunteers.
Topics: Adult; Blood Platelets; Drug Therapy, Combination; Humans; Male; Metoprolol; Middle Aged; Myocardial | 1984 |
Göteborg Metoprolol Trial: enzyme-estimated infarct size.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; He | 1984 |
Göteborg Metoprolol Trial: electrocardiographically estimated infarct size.
Topics: Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Humans; Metoprolol; Myocardial I | 1984 |
Göteborg Metoprolol Trial: design, patient characteristics and conduct.
Topics: Aged; Arrhythmias, Cardiac; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Electroca | 1984 |
Göteborg Metoprolol Trial: effects on chest pain.
Topics: Administration, Oral; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Injection | 1984 |
[Effect on mortality of metoprolol in acute myocardial infarction. A randomized double-blind trial (author's transl)].
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Clinical Trials as Topic; Electrocar | 1982 |
A double-blind trial of metoprolol in acute myocardial infarction. Effects on ventricular tachyarrhythmias.
Topics: Double-Blind Method; Drug Evaluation; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infa | 1983 |
Metoprolol treatment after acute myocardial infarction. Effects on ventricular arrhythmias and exercise tests during 6 months.
Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Electrocardiograph | 1981 |
Acute intervention with metoprolol in myocardial infarction.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Humans; Meto | 1981 |
Factors of importance for QRS complex recovery after acute myocardial infarction.
Topics: Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; L-La | 1982 |
[Effect of metoprolol on infarct size after acute myocardial infarction (a double-blind study) (author's transl)].
Topics: Adult; Aged; Clinical Trials as Topic; Creatine Kinase; Double-Blind Method; Electrocardiography; Fe | 1982 |
Effect of metoprolol on QTc intervals after acute myocardial infarction.
Topics: Adult; Aged; Digitalis Glycosides; Double-Blind Method; Electrocardiography; Female; Follow-Up Studi | 1980 |
Metoprolol and atropine in acute myocardial infarction.
Topics: Atropine; Drug Therapy, Combination; Humans; Metoprolol; Myocardial Infarction; Propanolamines | 1980 |
Comparison of the effects of amiodarone versus metoprolol on the frequency of ventricular arrhythmias and on mortality after acute myocardial infarction. SSSD Investigators. Spanish Study on Sudden Death.
Topics: Aged; Amiodarone; Cardiac Complexes, Premature; Death, Sudden, Cardiac; Female; Humans; Male; Metopr | 1993 |
Effects of beta receptor antagonists in patients with clinical evidence of heart failure after myocardial infarction: double blind comparison of metoprolol and xamoterol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Exercise Test; Fem | 1995 |
Metoprolol treatment for two years after coronary bypass grafting: effects on exercise capacity and signs of myocardial ischaemia.
Topics: Adrenergic beta-Antagonists; Aged; Coronary Artery Bypass; Double-Blind Method; Electrocardiography; | 1995 |
Utility of beta-blockade treatment for older postinfarction patients.
Topics: Age Factors; Aged; Aged, 80 and over; Female; Follow-Up Studies; Humans; Logistic Models; Male; Meto | 1995 |
ST segment tracking for rapid determination of patency of the infarct-related artery in acute myocardial infarction.
Topics: Anistreplase; Cardiac Catheterization; Confidence Intervals; Coronary Angiography; Coronary Disease; | 1995 |
Effects of captopril on plasma endothelin-1 during thrombolysis: preliminary findings.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Captopril; Double-Blind Method; Drug Therapy, Com | 1995 |
Effects of administration of captopril, metoprolol, and the captopril-metoprolol combination as adjuvant therapy during thrombolysis in acute myocardial infarction.
Topics: Captopril; Drug Combinations; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Single-Blind M | 1994 |
Effects of the administration of captopril, metoprolol and of the captopril-metoprolol combination as adjuvant therapy during thrombolysis in acute myocardial infarction.
Topics: Aged; Captopril; Chemotherapy, Adjuvant; Creatine Kinase; Dose-Response Relationship, Drug; Drug The | 1994 |
Ten-year mortality rate among patients in whom acute myocardial infarction was not confirmed in relation to clinical history and observations during hospital stay: experiences from the Göteborg Metoprolol Trial.
Topics: Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Multivariate | 1994 |
Ten-year mortality rate after development of acute myocardial infarction in relation to clinical history and observations during hospital stay: experience from the Göteborg metoprolol trial.
Topics: Adult; Aged; Female; Follow-Up Studies; Hospital Mortality; Hospitalization; Humans; Male; Medical H | 1993 |
Ten-year mortality among patients with suspected acute myocardial infarction in relation to early diagnosis.
Topics: Adult; Aged; Double-Blind Method; Female; Follow-Up Studies; Hemodynamics; Humans; Male; Metoprolol; | 1994 |
Incidence and significance of ventricular tachycardia and fibrillation in the absence of hypotension or heart failure in acute myocardial infarction treated with recombinant tissue-type plasminogen activator: results from the Thrombolysis in Myocardial In
Topics: Female; Heart Failure; Humans; Hypotension; Incidence; Male; Metoprolol; Middle Aged; Myocardial Inf | 1993 |
Effects of thrombolysis and atenolol or metoprolol on the signal-averaged electrocardiogram after acute myocardial infarction. Late Potentials Italian Study (LAPIS).
Topics: Aged; Atenolol; Drug Therapy, Combination; Electrocardiography; Female; Follow-Up Studies; Humans; I | 1993 |
Effects of metoprolol on heart rate variability in survivors of acute myocardial infarction.
Topics: Heart Rate; Humans; Male; Metoprolol; Myocardial Infarction; Prognosis | 1993 |
Evaluation of importance of central effects of atenolol and metoprolol measured by heart rate variability during mental performance tasks, physical exercise, and daily life in stable postinfarct patients.
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Atenolol; Autonomic Nervous System; Circadi | 1995 |
Effect of quinapril or metoprolol on heart rate variability in post-myocardial infarction patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibi | 1996 |
Influence of metoprolol on heart rate variability in survivors of remote myocardial infarction.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Heart Rate; Humans; Male; Metopro | 1996 |
Effect of metoprolol on death and cardiac events during a 2-year period after coronary artery bypass grafting. The MACB Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Coronary Artery Bypass | 1995 |
Effects of beta receptor antagonists on left ventricular function in patients with clinical evidence of heart failure after myocardial infarction. A double-blind comparison of metoprolol and xamoterol. Echocardiographic results from the Metoprolol and Xam
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Cardiac Output, Low; Double-Blind Method; Echo | 1996 |
Identification of viable myocardium early after acute myocardial infarction under beta-blockade by enoximone echocardiography.
Topics: Acute Disease; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Cardiotonic Agents; Dobutamine | 1997 |
Heart rate variability after acute myocardial infarction in patients treated with atenolol and metoprolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Autonomic Nervous System; Cross-Over Studies; De | 1997 |
Effect of metoprolol on the prognosis for patients with suspected acute myocardial infarction and indirect signs of congestive heart failure (a subgroup analysis of the Göteborg Metoprolol Trial).
Topics: Adrenergic beta-Antagonists; Adult; Aged; Female; Heart Failure; Humans; Injections, Intravenous; Ma | 1997 |
Lipophilic versus hydrophilic beta(1) blockers and the cardiac sympatho-vagal balance during stress and daily activity in patients after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Baroreflex; Cross-Over Studies; Double-Blind Met | 1998 |
Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study.
Topics: Adrenergic beta-Antagonists; Adult; Angioplasty, Balloon, Coronary; Diltiazem; Female; Humans; Isoso | 1998 |
A comparison of metoprolol and morphine in the treatment of chest pain in patients with suspected acute myocardial infarction--the MEMO study.
Topics: Adrenergic beta-Antagonists; Aged; Analgesics, Opioid; Angina Pectoris; Diagnosis, Differential; Fem | 1999 |
Effects of early treatment with captopril and metoprolol singly or together on six-month mortality and morbidity after acute myocardial infarction. Results of the RIMA (Rimodellamento Infarto Miocardico Acuto) study. The RIMA researchers.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Disease-Free | 1999 |
Which strategy is "best" after myocardial infarction? The Beta-blocker Strategy plus Implantable Cardioverter Defibrillator Trial: rationale and study design.
Topics: Adrenergic beta-Antagonists; Aged; Cause of Death; Combined Modality Therapy; Defibrillators, Implan | 1999 |
Effect of intravenous metoprolol before hospital admission on chest pain in suspected acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Analgesics, Opioid; Chest Pain; Coronary Angiography; Diag | 1999 |
Effects of long-term adrenergic beta-blockade on left ventricular diastolic filling in patients with acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Diastole; Double-Blind Method; Echocardiography; Echocardiography, Dopp | 1999 |
Effect of quinapril or metoprolol on circadian sympathetic and parasympathetic modulation after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Circadian Rhythm | 1999 |
Pain recollection after chest pain of cardiac origin.
Topics: Age Factors; Aged; Chest Pain; Cohort Studies; Double-Blind Method; Female; Follow-Up Studies; Human | 1999 |
Randomised training after myocardial infarction: short and long-term effects of exercise training after myocardial infarction in patients on beta-blocker treatment. A randomized, controlled study.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Electrocardiography; Exercise Test; Exercise Therapy; F | 2000 |
Improvement of exercise capacity and left ventricular diastolic function with metoprolol XL after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Coronary Circulation; Diastole; Double-Blind Method; Echoc | 2000 |
Prognostic implications of intima-media thickness and plaques in the carotid and femoral arteries in patients with stable angina pectoris.
Topics: Aged; Angina Pectoris; Arteriosclerosis; Carotid Arteries; Carotid Artery Diseases; Coronary Artery | 2001 |
Autonomic dysfunction in patients with mild heart failure and coronary artery disease and the effects of add-on beta-blockade.
Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Autonomic Nervous System; Case-Control Stu | 2001 |
Rationale, design and organization of the Second Chinese Cardiac Study (CCS-2): a randomized trial of clopidogrel plus aspirin, and of metoprolol, among patients with suspected acute myocardial infarction. Second Chinese Cardiac Study (CCS-2) Collaborativ
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; China; Clopidogrel; D | 2000 |
Long-term mortality after acute myocardial infarction in relation to prescribed dosages of a beta-blocker at hospital discharge.
Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Me | 2000 |
Effect of early treatment with captopril and metoprolol singly and together on postinfarction left ventricular remodeling.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Therapy, Comb | 2001 |
Neurohormonal activation in heart failure after acute myocardial infarction treated with beta-receptor antagonists.
Topics: Acute Disease; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Atrial Natriuretic Facto | 2002 |
Prognostic implications of autonomic function assessed by analyses of catecholamines and heart rate variability in stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Anti-Arrhythmia Agents; Autonomic Nervous System Diseases; Biomarkers; | 2002 |
[Effects of metoprolol on the signal averaged electrocardiogram and QT dispersion in acute myocardial infarction].
Topics: Administration, Oral; Anti-Arrhythmia Agents; Drug Administration Schedule; Electrocardiography; Fem | 2002 |
The use of dobutamine in myocardial infarction for reversal of the cardiodepressive effect of metoprolol.
Topics: Acute Disease; Adult; Aged; Catecholamines; Clinical Trials as Topic; Dobutamine; Female; Hemodynami | 1978 |
Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle.
Topics: Amlodipine; Angina Pectoris; Diastole; Dose-Response Relationship, Drug; Drug Administration Schedul | 1992 |
Invasive versus conservative strategy after thrombolytic therapy for acute myocardial infarction in patients with antecedent angina. A report from Thrombolysis in Myocardial Infarction Phase II (TIMI II).
Topics: Administration, Oral; Aged; Angina Pectoris; Cardiac Catheterization; Combined Modality Therapy; Cor | 1992 |
Prognostic importance of predischarge exercise capacity for long-term mortality and non-fatal myocardial infarction in patients admitted for suspected acute myocardial infarction and treated with metoprolol.
Topics: Double-Blind Method; Exercise Test; Exercise Tolerance; Female; Humans; Male; Metoprolol; Middle Age | 1992 |
Incidence and prognostic implications of heart block complicating inferior myocardial infarction treated with thrombolytic therapy: results from TIMI II.
Topics: Female; Follow-Up Studies; Heart Block; Humans; Incidence; Male; Metoprolol; Middle Aged; Myocardial | 1992 |
[Wake up time, thrombocyte aggregation and the risk of acute coronary heart disease. The TRIMM (Trigger and Mechanisms of Myocardial Infarct) Study Group].
Topics: Aged; Blood Pressure Monitors; Circadian Rhythm; Coronary Disease; Double-Blind Method; Epinephrine; | 1992 |
Enalaprilat in acute myocardial infarction: tolerability and effects on the renin-angiotensin system.
Topics: Aged; Blood Pressure; Enalaprilat; Female; Furosemide; Humans; Infusions, Intravenous; Injections, I | 1991 |
Immediate versus deferred beta-blockade following thrombolytic therapy in patients with acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI) II-B Study.
Topics: Adrenergic beta-Antagonists; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; R | 1991 |
Should beta-blockers be given immediately and concomitantly with thrombolytic therapy in acute myocardial infarction?
Topics: Adrenergic beta-Antagonists; Humans; Metoprolol; Myocardial Infarction; Thrombolytic Therapy; Time F | 1991 |
Coronary artery disease can be prevented by antihypertensive therapy: experiences from the MAPHY Study.
Topics: Adult; Antihypertensive Agents; Benzothiadiazines; Cerebrovascular Disorders; Coronary Disease; Deat | 1990 |
Long-term prognosis after early intervention with metoprolol in suspected acute myocardial infarction: experiences from the MIAMI Trial. The MIAMI Trial Research Group.
Topics: Double-Blind Method; Follow-Up Studies; Humans; Metoprolol; Middle Aged; Myocardial Infarction; Prog | 1991 |
Early treatment with thrombolysis and beta-blockade in suspected acute myocardial infarction: results from the TEAHAT Study.
Topics: Aged; Drug Therapy, Combination; Electrocardiography; Female; Humans; Male; Metoprolol; Middle Aged; | 1991 |
Selective versus routine predischarge coronary arteriography after therapy with recombinant tissue-type plasminogen activator, heparin and aspirin for acute myocardial infarction. TIMI II Investigators.
Topics: Aged; Aspirin; Coronary Angiography; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Co | 1991 |
Hemorrhagic events during therapy with recombinant tissue-type plasminogen activator, heparin, and aspirin for acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI), Phase II Trial.
Topics: Aspirin; Coronary Artery Bypass; Dose-Response Relationship, Drug; Drug Administration Schedule; Dru | 1991 |
Hemorrhagic events during therapy with recombinant tissue-type plasminogen activator, heparin, and aspirin for acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI), Phase II Trial.
Topics: Aspirin; Coronary Artery Bypass; Dose-Response Relationship, Drug; Drug Administration Schedule; Dru | 1991 |
Hemorrhagic events during therapy with recombinant tissue-type plasminogen activator, heparin, and aspirin for acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI), Phase II Trial.
Topics: Aspirin; Coronary Artery Bypass; Dose-Response Relationship, Drug; Drug Administration Schedule; Dru | 1991 |
Hemorrhagic events during therapy with recombinant tissue-type plasminogen activator, heparin, and aspirin for acute myocardial infarction. Results of the Thrombolysis in Myocardial Infarction (TIMI), Phase II Trial.
Topics: Aspirin; Coronary Artery Bypass; Dose-Response Relationship, Drug; Drug Administration Schedule; Dru | 1991 |
Prognosis during one year for patients with myocardial infarction in relation to the development of Q waves: experiences from the Miami trial.
Topics: Electrocardiography; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Multicenter S | 1990 |
Mortality and morbidity during one year of follow-up in suspected acute myocardial infarction in relation to early diagnosis: experiences from the MIAMI trial.
Topics: Angina Pectoris; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Humans; Incide | 1990 |
Use of heart rate spectral analysis to study the effects of calcium channel blockers on sympathetic activity after myocardial infarction.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Heart Rate; Humans; Male; Metoprol | 1990 |
The effects of metoprolol given early in acute myocardial infarction on ventricular arrhythmias.
Topics: Administration, Oral; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as Topic; | 1986 |
Evaluation of antiarrhythmic effect of metoprolol treatment after acute myocardial infarction: relationship between treatment responses and survival during a 3-year follow-up.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Clinical Trials as | 1986 |
[Are anti-arrhythmia agents superior to a beta blocker in treating life-threatening ventricular arrhythmias? Preliminary results of a controlled study].
Topics: Anti-Arrhythmia Agents; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Clinical Trials as | 1986 |
[Dose-dependent anti-arrhythmia effect of retard metoprolol in coronary disease patients with ventricular arrhythmia].
Topics: Adult; Cardiac Complexes, Premature; Clinical Trials as Topic; Coronary Disease; Delayed-Action Prep | 1988 |
Nifedipine and metoprolol in unstable angina: findings from the Holland Interuniversity Nifedipine/Metoprolol Trial (HINT).
Topics: Aged; Angina Pectoris; Angina, Unstable; Double-Blind Method; Drug Therapy, Combination; Electrocard | 1987 |
Early use of metoprolol and serum potassium in suspected acute myocardial infarction.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Myocar | 1989 |
Effect of metoprolol on early exercise-induced ST-segment changes and ventricular arrhythmias in patients with suspected acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Exercise T | 1989 |
Early treatment with intravenous metoprolol for suspected acute myocardial infarction: a phase IV United States trial. Phase IV Metoprolol in Myocardial Infarction Study Group.
Topics: Adult; Aged; Clinical Trials as Topic; Data Collection; Female; Humans; Hypotension; Infusions, Intr | 1989 |
Effects of metoprolol on mortality and late infarction in diabetics with suspected acute myocardial infarction. Retrospective data from two large studies.
Topics: Diabetes Complications; Diabetes Mellitus; Humans; Metoprolol; Multicenter Studies as Topic; Myocard | 1989 |
Effect of early metoprolol injection followed by oral dosage on CK-MB release, and myocardial function in suspected acute myocardial infarction. A double-blind controlled study.
Topics: Clinical Trials as Topic; Creatine Kinase; Double-Blind Method; Electrocardiography; Female; Humans; | 1989 |
Metoprolol in acute myocardial infarction (MIAMI). A randomised placebo-controlled international trial. The MIAMI Trial Research Group.
Topics: Aged; Aspartate Aminotransferases; Clinical Trials as Topic; Double-Blind Method; Electrocardiograph | 1985 |
Metoprolol in acute myocardial infarction. Patients and methods. The MIAMI Trial Research Group.
Topics: Aged; Clinical Trials as Topic; Computers; Double-Blind Method; Drug Packaging; Female; Humans; Male | 1985 |
Use of beta adrenoceptor blockade during and after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Atenolol; Cardiotonic Agents; Clinical Trials as | 1986 |
[Effect of beta-adrenolytic drugs on the survival of patients after myocardial infarction].
Topics: Adrenergic beta-Antagonists; Adult; Aftercare; Aged; Clinical Trials as Topic; Follow-Up Studies; Hu | 1986 |
Intravenous beta-blockade during acute myocardial infarction.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Atenolol; Clinical Trials as Topic; Humans; Injec | 1986 |
Early treatment of unstable angina in the coronary care unit: a randomised, double blind, placebo controlled comparison of recurrent ischaemia in patients treated with nifedipine or metoprolol or both. Report of The Holland Interuniversity Nifedipine/Meto
Topics: Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Care Units; Double-Blind | 1986 |
[2 international multicenter studies. Early treatment with beta blockaders in acute chest pain reduces the risk of definitive development of myocardial infarction].
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Chest Pain; Clinical Trials as Topic; Humans; Metoprolo | 1987 |
Efficacy of nifedipine and metoprolol in the early treatment of unstable angina in the coronary care unit: findings from the Holland Interuniversity Nifedipine/metoprolol Trial (HINT).
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coro | 1987 |
The Lopressor Intervention Trial: multicentre study of metoprolol in survivors of acute myocardial infarction. Lopressor Intervention Trial Research Group.
Topics: Aged; Cause of Death; Clinical Trials as Topic; Death, Sudden; Double-Blind Method; Female; Humans; | 1987 |
The safety of combined thrombolysis and beta-adrenergic blockade in patients with acute myocardial infarction. A randomized study.
Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Echocardiography; Female; Fibrinolytic Agent | 1988 |
Responsiveness to diving reflex after acute myocardial infarction. Influence of early beta-adrenoceptor blocker therapy.
Topics: Adrenergic beta-Antagonists; Aged; Clinical Trials as Topic; Cold Temperature; Double-Blind Method; | 1988 |
Effect of metoprolol in postinfarction patients with increased heart size.
Topics: Cardiomegaly; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Male | 1986 |
Body temperature in acute myocardial infarction and its relation to early intervention with metoprolol.
Topics: Adult; Aged; Body Temperature; Clinical Trials as Topic; Double-Blind Method; Fever; Humans; Metopro | 1988 |
Does acute-phase beta-blockade reduce mortality in acute myocardial infarction by limiting infarct size?
Topics: Aspartate Aminotransferases; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Hea | 1988 |
Morbidity and quality of life 5 years after early intervention with metoprolol in suspected acute myocardial infarction.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Follow-Up S | 1988 |
Quality of life after myocardial infarction: effect of long term metoprolol on mortality and morbidity.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Myocar | 1986 |
Why doctors must grapple with health economics.
Topics: Clinical Trials as Topic; Cost-Benefit Analysis; Economics, Medical; Humans; Metoprolol; Myocardial | 1987 |
Economic consequences of postinfarction prophylaxis with beta blockers: cost effectiveness of metoprolol.
Topics: Aged; Clinical Trials as Topic; Costs and Cost Analysis; Delivery of Health Care; Female; Humans; Ma | 1987 |
Haemodynamic effects of metoprolol and intravenous nitroglycerin versus metoprolol alone in patients with acute myocardial infarction.
Topics: Aged; Drug Evaluation; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Metoprolol; Mi | 1987 |
Influence of long-term metoprolol treatment on early and late exercise test performance after acute myocardial infarction.
Topics: Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Exercise Test; Female; Heart Rat | 1988 |
Prediction of rupture in acute myocardial infarction.
Topics: Aged; Clinical Trials as Topic; Coronary Care Units; Double-Blind Method; Electrocardiography; Heart | 1988 |
Effects on mortality during five years after early intervention with metoprolol in suspected acute myocardial infarction.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle | 1988 |
Thromboatherosclerotic complications in hypertensives: results of the Stockholm Metoprolol (secondary prevention) Trial.
Topics: Arteriosclerosis; Cause of Death; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertensio | 1988 |
Metoprolol in acute myocardial infarction reduces ventricular arrhythmias both in the early stage and after the acute event.
Topics: Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Female; Heart Ventricles; Human | 1987 |
Five-year mortality rate in relation to enzyme-estimated infarct size in acute myocardial infarction.
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Clinical Enzyme Tests; Clinical Tria | 1987 |
Beta-adrenergic blockade in acute myocardial infarction: a haemodynamic and radionuclide study.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Heart; Hemodynamics; Humans; Male; Metoprolol | 1987 |
Effect of metoprolol on the submaximal stress test performed early after acute myocardial infarction.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Exe | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Treatment, observations, and outcome events.
Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug | 1987 |
Plasma catecholamine levels in acute myocardial infarction: influence of beta-adrenergic blockade and relation to central hemodynamics.
Topics: Administration, Oral; Aged; Double-Blind Method; Epinephrine; Female; Hemodynamics; Humans; Male; Me | 1988 |
Infarct size limitation after early intervention with metoprolol in the MIAMI Trial.
Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Child; Child, Preschool; Creatine Kinase; Doub | 1988 |
Prognosis after withdrawal of chronic postinfarction metoprolol treatment: a 2-7 year follow-up.
Topics: Adolescent; Adult; Aged; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Myocardia | 1988 |
Postinfarction metoprolol treatment: effects on prognosis in relation to serum cholesterol concentrations.
Topics: Cholesterol; Double-Blind Method; Female; Humans; Male; Metoprolol; Myocardial Infarction; Placebos; | 1987 |
Variability, prediction and prognostic significance of chest pain in acute myocardial infarction.
Topics: Analgesia; Clinical Trials as Topic; Humans; Metoprolol; Morphine; Myocardial Infarction; Pain; Prog | 1986 |
The influence of early intervention in acute myocardial infarction on long-term mortality and morbidity as assessed in the Göteborg metoprolol trial.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Disability Evaluation; Follow-Up Studies; Hu | 1986 |
Reduction of nonfatal reinfarctions in patients with a history of hypertension by chronic postinfarction treatment with metoprolol.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Male | 1986 |
Central haemodynamics in acute myocardial infarction. Natural history, relation to enzyme release and effects of metoprolol.
Topics: Aged; Aspartate Aminotransferases; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Hemody | 1986 |
Cardiovascular reactivity to mental stress during gradual withdrawal of chronic postinfarction treatment with metoprolol.
Topics: Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular System; Clinical Trials as Topic; | 1986 |
Central haemodynamic effects of metoprolol early in acute myocardial infarction. A placebo controlled randomized study of patients with low heart rate.
Topics: Aged; Cardiac Catheterization; Cardiac Output; Clinical Trials as Topic; Heart Rate; Hemodynamics; H | 1986 |
Experiences from the use of twenty-four precordial chest leads in suspected acute myocardial infarction.
Topics: Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Heart Conduction System; Humans; | 1986 |
QRS complex recovery during one year after acute myocardial infarction.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Heart Rate; Humans; | 1987 |
Left ventricular function following withdrawal of chronic metoprolol treatment in patients with ischaemic heart disease. A double blind study.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; Echocardiogra | 1986 |
Serum lipids and lipoproteins in ischaemic heart disease following withdrawal of long-term metoprolol treatment.
Topics: Adult; Aged; Cholesterol; Drug Administration Schedule; Humans; Lipids; Lipoproteins, HDL; Lipoprote | 1987 |
Abstracts of papers presented at an international symposium on the role of beta-blockade in acute myocardial ischaemia and infarction, Rome, October 29-30, 1984.
Topics: Clinical Trials as Topic; Coronary Disease; Humans; Metoprolol; Myocardial Infarction | 1985 |
ADP-induced platelet aggregation and metoprolol treatment of myocardial infarction patients. A controlled study.
Topics: Adenosine Diphosphate; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Metoprol | 1985 |
[Beta-blockers in the acute phase of myocardial infarction. Echographic study].
Topics: Clinical Trials as Topic; Female; Hemodynamics; Humans; Male; Metoprolol; Middle Aged; Myocardial In | 1985 |
Tolerability to treatment with metoprolol in acute myocardial infarction in relation to age.
Topics: Adult; Age Factors; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Hemodynamic | 1985 |
Long-term treatment with metoprolol after myocardial infarction: effect on 3 year mortality and morbidity.
Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Cerebrovascular Disorders; Clinical Trials as Topic; Co | 1985 |
Left ventricular performance in unstable angina: assessment with radionuclide techniques.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Angiography; Coronary Disease; | 1985 |
Very early intervention with metoprolol in suspected acute myocardial infarction.
Topics: Aged; Clinical Trials as Topic; Death, Sudden; Double-Blind Method; Female; Follow-Up Studies; Human | 1985 |
Metoprolol in acute myocardial infarction. Mortality. The MIAMI Trial Research Group.
Topics: Aged; Clinical Trials as Topic; Female; Heart Rate; Humans; Male; Metoprolol; Middle Aged; Myocardia | 1985 |
Metoprolol in acute myocardial infarction. Development of myocardial infarction. The MIAMI Trial Research Group.
Topics: Clinical Trials as Topic; Electrocardiography; Humans; Metoprolol; Myocardial Infarction; Recurrence | 1985 |
Metoprolol in acute myocardial infarction. Enzymatic estimation of infarct size. The MIAMI Trial Research Group.
Topics: Aspartate Aminotransferases; Blood Pressure; Clinical Trials as Topic; Creatine Kinase; Electrocardi | 1985 |
Metoprolol in acute myocardial infarction. Arrhythmias. The MIAMI Trial Research Group.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Clinical Trials as Topic; Humans; Metopro | 1985 |
Metoprolol in acute myocardial infarction. Other clinical findings and tolerability. The MIAMI Trial Research Group.
Topics: Anti-Arrhythmia Agents; Clinical Trials as Topic; Drug Therapy, Combination; Drug Tolerance; Humans; | 1985 |
Hemodynamic effects of metoprolol in acute myocardial infarction. A randomized, placebo-controlled multicenter study.
Topics: Aged; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Metop | 1985 |
[Metoprolol in acute myocardial infarction--clinical effect and tolerance].
Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middl | 1985 |
Metoprolol in acute myocardial infarction. Patient population. The MIAMI Trial Research Group.
Topics: Adult; Aged; Clinical Trials as Topic; Diagnosis-Related Groups; Electrocardiography; Female; Humans | 1985 |
258 other studies available for metoprolol and Cardiovascular Stroke
| Article | Year |
|---|---|
Identified Three Interferon Induced Proteins as Novel Biomarkers of Human Ischemic Cardiomyopathy.
Topics: Animals; Apoptosis Regulatory Proteins; Biomarkers; Cardiomyopathies; Disease Models, Animal; Gene R | 2021 |
Association Between Metoprolol and Prognosis of COVID-19 Patients.
Topics: COVID-19; Humans; Metoprolol; Myocardial Infarction; Prognosis; SARS-CoV-2 | 2022 |
Effect of metoprolol tartrate tablets and recombinant human B-type natriuretic peptide on the sudden cardiac death and malignant arrhythmias in patients with acute myocardial infarction and heart failure.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biomarke | 2021 |
Remuscularization with triiodothyronine and β
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Metoprolol; Mice; Myocardial Infarction; Myocardium | 2022 |
Early donepezil monotherapy or combination with metoprolol significantly prevents subsequent chronic heart failure in rats with reperfused myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Donepezil; Heart Failure; Metoprolol; Myocardial Infarction; R | 2022 |
Effects of Dapagliflozin in Combination with Metoprolol Sustained-Release Tablets on Prognosis and Cardiac Function in Patients with Acute Myocardial Infarction after PCI.
Topics: Benzhydryl Compounds; Biomarkers; C-Reactive Protein; Delayed-Action Preparations; Drug Therapy, Com | 2022 |
Impact of Diabetes Mellitus on Benefit of β-Blocker Therapy After Myocardial Infarction.
Topics: Adrenergic beta-Antagonists; Carvedilol; Diabetes Mellitus; Humans; Metoprolol; Myocardial Infarctio | 2023 |
Metoprolol protects against myocardial infarction by inhibiting miR-1 expression in rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Cell Communication; Cells, Cultured; Connexin 43; D | 2020 |
Down syndrome, severe psoriasis, and increased risk for cardiovascular events.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Down Syndrome; Fat | 2019 |
Impact of genotype-predicted CYP2D6 metabolism on clinical effects and tolerability of metoprolol in patients after myocardial infarction - a prospective observational study.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Aged; Cytochrome P-450 CYP2D6; Female; Genotype; Hemo | 2020 |
Metabolomic profiling of metoprolol-induced cardioprotection in a murine model of acute myocardial ischemia.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Male; Metabolomics; Metoprolol; Mice; Mice, Inb | 2020 |
Ivabradine is as effective as metoprolol in the prevention of ventricular arrhythmias in acute non-reperfused myocardial infarction in the rat.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium Signaling; Cells, Cultured; Heart Rate; | 2020 |
Beta Blockade in Patients After Acute Myocardial Infarction.
Topics: Humans; Magnetic Resonance Spectroscopy; Metoprolol; Myocardial Infarction; Patients; Prognosis | 2020 |
Metoprolol exerts a non-class effect against ischaemia-reperfusion injury by abrogating exacerbated inflammation.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Humans; Inflammation; Metoprolol; Mice; Myocardial I | 2020 |
Comparison of Metoprolol Versus Carvedilol After Acute Myocardial Infarction.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Carvedilol; Female; Hospitalization; Humans; Kaplan-M | 2021 |
Comparison of carvedilol versus metoprolol in patients with acute myocardial infarction: A protocol for systematic review and meta-analysis.
Topics: Arrhythmias, Cardiac; Carvedilol; Death, Sudden, Cardiac; Humans; Meta-Analysis as Topic; Metoprolol | 2021 |
Acute Myocardial Infarction from Coronary Vasospasm Precipitated by Pseudoephedrine and Metoprolol Use.
Topics: Anti-Arrhythmia Agents; Asthma; Atrial Fibrillation; Bronchodilator Agents; Coronary Angiography; Co | 2017 |
Neutrophil stunning by metoprolol reduces infarct size.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Cell Movement; Hematopoietic Stem Cells; Humans; Me | 2017 |
Allogeneic pASC transplantation in humanized pigs attenuates cardiac remodeling post-myocardial infarction.
Topics: Adipose Tissue; Animals; Coronary Circulation; Enalaprilat; Female; Hemodynamics; Mesenchymal Stem C | 2017 |
Stunning neutrophils changes the forecast: No more showers.
Topics: Blood Platelets; Humans; Male; Metoprolol; Microvessels; Myocardial Infarction; Neutrophils | 2017 |
Coronary Vasospasm Precipitated by Pseudoephedrine, Not Metoprolol.
Topics: Coronary Vasospasm; Metoprolol; Myocardial Infarction; Pseudoephedrine | 2017 |
Age Does Not Affect Metoprolol's Effect on Perioperative Outcomes (From the POISE Database).
Topics: Adrenergic beta-1 Receptor Antagonists; Age Factors; Aged; Aged, 80 and over; Databases, Factual; Fe | 2018 |
Comparison of Therapeutic Triiodothyronine Versus Metoprolol in the Treatment of Myocardial Infarction in Rats.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Echocardiography; Ele | 2018 |
Comparison between renal denervation and metoprolol on the susceptibility of ventricular arrhythmias in rats with myocardial infarction.
Topics: Animals; Arrhythmias, Cardiac; Connexin 43; Denervation; Disease Models, Animal; Drug Administration | 2018 |
Effect of ethanolic extract of Cyperus rotundus L. against isoprenaline induced cardiotoxicity.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarker | 2016 |
Impact of a Metoprolol Extended Release Shortage on Post-Myocardial Infarction β-Blocker Utilization, Adherence, and Rehospitalization.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Databases, Factual; Delayed-Action Preparations; Femal | 2018 |
Antidepressant-like effects of ginseng fruit saponin in myocardial infarction mice.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Cerebral Cortex; Depression; Disease Models, Anima | 2019 |
Excessive sympathoactivation and deteriorated heart function after myocardial infarction in male ghrelin knockout mice.
Topics: Animals; Blood Pressure; Ghrelin; Heart; Heart Failure; Heart Rate; Male; Metoprolol; Mice; Mice, In | 2013 |
Reversal of cardiac dysfunction and subcellular alterations by metoprolol in heart failure due to myocardial infarction.
Topics: Adenosine Triphosphatases; Animals; Calcium; Calcium-Binding Proteins; Cardiac Output; Dopamine; Epi | 2013 |
Update on pharmacological advances.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Carvedilol; Disea | 2004 |
Metoprolol-mediated amelioration of sympathetic nerve sprouting after myocardial infarction.
Topics: Animals; Coronary Vessels; Heart; I-kappa B Proteins; Interleukin-1beta; Ligation; Male; Metoprolol; | 2013 |
Intravenous β-blockers in primary percutaneous coronary intervention: new hope for an old therapy.
Topics: Adrenergic beta-Antagonists; Cardiotonic Agents; Female; Humans; Male; Metoprolol; Myocardial Infarc | 2013 |
Pharmacotherapy: β-Blocker therapy before PCI for STEMI reduces infarct size.
Topics: Adrenergic beta-Antagonists; Cardiotonic Agents; Female; Humans; Male; Metoprolol; Myocardial Infarc | 2013 |
Effects of Nardostachys chinensis on spontaneous ventricular arrhythmias in rats with acute myocardial infarction.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Blotting, Western; Connexin 43; Drugs, Chinese Herb | 2014 |
Block the ischemia and reperfusion damage: an old adjunctive drug for a new reperfusion strategy.
Topics: Adrenergic beta-1 Receptor Antagonists; Early Medical Intervention; Humans; Metoprolol; Myocardial I | 2014 |
Sorafenib cardiotoxicity increases mortality after myocardial infarction.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cats; Cell Proliferation; Cells, Cultured; Disease Models | 2014 |
Effects of metoprolol and small intestine RNA on marrow-derived endothelial progenitor cells applied for autograft transplantation in heart disease.
Topics: Animals; Apoptosis; Bone Marrow Cells; Endothelial Cells; Intestine, Small; Lactate Dehydrogenases; | 2014 |
Mineralocorticoid and AT1 receptors in the paraventricular nucleus contribute to sympathetic hyperactivity and cardiac dysfunction in rats post myocardial infarct.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Baroreflex; Male; Metoprolol; Myocardial Infarctio | 2014 |
Letter by Argulian and Messerli regarding article, "effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection Durin
Topics: Adrenergic beta-Antagonists; Cardiotonic Agents; Female; Humans; Male; Metoprolol; Myocardial Infarc | 2014 |
Response to letter regarding article, "effect of early metoprolol on infarct size in ST-segment-elevation myocardial infarction patients undergoing primary percutaneous coronary intervention: the Effect of Metoprolol in Cardioprotection During an Acute My
Topics: Adrenergic beta-Antagonists; Cardiotonic Agents; Female; Humans; Male; Metoprolol; Myocardial Infarc | 2014 |
Health and cost benefits associated with the use of metoprolol in heart attack patients.
Topics: Adrenergic beta-1 Receptor Antagonists; Cost of Illness; Cost-Benefit Analysis; Drug Costs; Heart Fa | 2014 |
A clinical study about contrast nephropathy: risk factors and the role of beta blockers.
Topics: Adrenergic beta-Antagonists; Carbazoles; Carvedilol; Contrast Media; Cross-Sectional Studies; Female | 2015 |
It takes the right medications to prevent a million heart attacks and strokes.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Health Promoti | 2014 |
Spontaneous coronary artery dissection in a parturient with Nail-Patella syndrome.
Topics: Adult; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antidiuretic | 2015 |
Reply: early intravenous beta-blockade before primary percutaneous coronary intervention gives major benefits apparently without side effects.
Topics: Adrenergic beta-1 Receptor Antagonists; Early Medical Intervention; Humans; Metoprolol; Myocardial I | 2014 |
Early intravenous beta-blockade before primary percutaneous coronary intervention gives major benefits, apparently without side effects.
Topics: Adrenergic beta-1 Receptor Antagonists; Early Medical Intervention; Humans; Metoprolol; Myocardial I | 2014 |
Web Exclusives. The consult guys--balancing the medication portfolio 5 years after a heart attack.
Topics: Adrenergic beta-1 Receptor Antagonists; Aspirin; Clopidogrel; Drug Therapy, Combination; Evidence-Ba | 2014 |
Myocardial bridging in a man with non-ST-elevation myocardial infarction.
Topics: Adenosine; Adrenergic beta-Antagonists; Aged; Blood Pressure; Cardiac Catheterization; Coronary Angi | 2015 |
Effects of chronic treatment with the new ultra-long-acting β2 -adrenoceptor agonist indacaterol alone or in combination with the β1 -adrenoceptor blocker metoprolol on cardiac remodelling.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Animals; Blood Pressure | 2015 |
Chest pain · shortness of breath · fever and nausea · Dx?
Topics: Adult; Antihypertensive Agents; Chest Pain; Diagnosis, Differential; Diuretics; Electrocardiography; | 2015 |
Screening β1AR inhibitors by cell membrane chromatography and offline UPLC/MS method for protecting myocardial ischemia.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Apoptosis; Berberine; Binding, Competitive; Cell Me | 2015 |
TSC-22 up-regulates collagen 3a1 gene expression in the rat heart.
Topics: Animals; Antihypertensive Agents; Cells, Cultured; Collagen Type III; Female; Gene Expression; Gene | 2015 |
Intravenous Beta-Blockers for Cardioprotection in STEMI: The Saga Continues.
Topics: Adrenergic beta-Antagonists; Humans; Metoprolol; Myocardial Infarction; ST Elevation Myocardial Infa | 2016 |
Intravenous Beta-Blockade for Limiting Myocardial Infarct Size: Rejuvenation of a Concept.
Topics: Humans; Metoprolol; Myocardial Infarction; Rejuvenation | 2016 |
Leukocyte-Expressed β2-Adrenergic Receptors Are Essential for Survival After Acute Myocardial Injury.
Topics: Aged; Aged, 80 and over; Animals; Disease Models, Animal; Female; Genetic Vectors; Heart Rupture; Hu | 2016 |
CASE 11-2016 Perioperative Coronary Thrombosis in a Patient With Multiple Second-Generation Drug-Eluting Stents: Is It Time for a Paradigm Shift?
Topics: Analgesics, Opioid; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopid | 2016 |
[The role of beta-adrenoblockers and If-inhibitor ivabradine in lowering of rate of development of cardiac complications after carotid endarterectomy].
Topics: Adrenergic beta-Antagonists; Benzazepines; Carotid Artery Diseases; Drug Therapy, Combination; Endar | 2008 |
Differential role of calcium/calmodulin-dependent protein kinase II in desflurane-induced preconditioning and cardioprotection by metoprolol: metoprolol blocks desflurane-induced preconditioning.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiotonic Agents; Desflurane; Ischemi | 2008 |
Mortality and reinfarction among patients using different beta-blockers for secondary prevention after a myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Bisoprolol; Female; Humans; Kaplan-Meier Estimate; Male | 2009 |
Perioperative beta blockade.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Comorbidity; Humans; Hypotension; Intraoperative Compl | 2008 |
Prevalent role of Akt and ERK activation in cardioprotective effect of Ca(2+) channel- and beta-adrenergic receptor blockers.
Topics: Adrenergic beta-Antagonists; Animals; Benzimidazoles; Calcium Channel Blockers; Cardiotonic Agents; | 2009 |
Acute myocardial infarction in pregnancy.
Topics: Adult; Angioplasty, Balloon, Coronary; Anticoagulants; Apgar Score; Aspirin; Cesarean Section; Coron | 2008 |
[Effects of carvedilol and metoprolol on cardiac fibrosis in rats with experimental myocardial infarction].
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Collagen; Disease Models, Animal; Fibr | 2008 |
Effects of ivabradine and metoprolol on cardiac angiogenesis and endothelial dysfunction in rats with heart failure.
Topics: Animals; Benzazepines; Heart Failure; Heart Rate; Ivabradine; Male; Metoprolol; Myocardial Infarctio | 2009 |
Reduction in myocardial infarct size at 48 hours after brief intravenous infusion of ATL-146e, a highly selective adenosine A2A receptor agonist.
Topics: Adenosine A2 Receptor Agonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Combined Modality T | 2009 |
[Beta-blockers in patients undergoing noncardiac surgery: implications of the POISE study].
Topics: Adrenergic beta-Antagonists; Bradycardia; Contraindications; Female; Forecasting; Heart; Heart Arres | 2009 |
Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach.
Topics: Adrenergic beta-Antagonists; Animals; Calcium Signaling; Cardiomegaly; Disease Models, Animal; Fibro | 2009 |
Right ventricular function in ST elevation myocardial infarction: effect of reperfusion.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angioplasty, Balloon, Coronary; Atorvastatin; Clopidogrel; | 2009 |
The cardioprotection granted by metoprolol is restricted to its administration prior to coronary reperfusion.
Topics: Animals; Apoptosis; Cardiotonic Agents; Male; Metoprolol; Myocardial Infarction; Myocardial Reperfus | 2011 |
Therapeutic innovations, diminishing returns, and control rate preservation.
Topics: Angioplasty, Balloon, Coronary; Biomarkers; Cardiovascular Agents; Clopidogrel; Diagnosis, Different | 2009 |
The experts debate: perioperative beta-blockade for noncardiac surgery--proven safe or not?
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Humans; Hypotension; Metoprolol; Myocardial In | 2009 |
Beta-blockers and non-cardiac operations what will change after the POISE study?: ?qué cambia después del estudio POISE?
Topics: Adrenergic beta-Antagonists; Humans; Metoprolol; Myocardial Infarction; Perioperative Care; Randomiz | 2009 |
Metoprolol treatment lowers thrombospondin-4 expression in rats with myocardial infarction and left ventricular hypertrophy.
Topics: Animals; Antihypertensive Agents; Hypertension; Hypertrophy, Left Ventricular; Male; Metoprolol; Myo | 2010 |
Divergent effects of losartan and metoprolol on cardiac remodeling, c-kit+ cells, proliferation and apoptosis in the left ventricle after myocardial infarction.
Topics: Animals; Antihypertensive Agents; Apoptosis; Cell Count; Cell Proliferation; Heart Ventricles; Inter | 2009 |
Beta(2)-adrenoceptor agonist clenbuterol reduces infarct size and myocardial apoptosis after myocardial ischaemia/reperfusion in anaesthetized rats.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Animals; Apoptosis; Clenbuterol; GTP- | 2010 |
Which beta-blocker is most effective in heart failure?
Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Bisoprolol; Carbazoles; Carvedilol; Clinical Tria | 2010 |
Carvedilol administration in acute myocardial infarction results in stronger inhibition of early markers of left ventricular remodeling than metoprolol.
Topics: Animals; Biomarkers; Carbazoles; Carvedilol; Down-Regulation; Metoprolol; Myocardial Infarction; Pro | 2011 |
Has the ClOpidogrel and Metoprolol in Myocardial Infarction Trial (COMMIT) of early β-blocker use in acute coronary syndromes impacted on clinical practice in Canada? Insights from the Global Registry of Acute Coronary Events (GRACE).
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Canada; Clopidogrel; | 2011 |
Selection of optimal dose of beta-blocker treatment in myocardial infarction patients based on changes in synchronization between 0.1 Hz oscillations in heart rate and peripheral microcirculation.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Dose-Response Relationship, Drug; Electrocardiography; Fem | 2012 |
β-Adrenergic receptor antagonists ameliorate myocyte T-tubule remodeling following myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Caveolin 3; Male; Membrane Proteins; M | 2012 |
Usefulness of C-reactive protein as a marker of early post-infarct left ventricular systolic dysfunction.
Topics: Aged; Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Antihypertensive Agents; Aspirin; Biom | 2012 |
The effect of c-fos on acute myocardial infarction and the significance of metoprolol intervention in a rat model.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Animals; Female; Gene Expression; | 2013 |
High-frequency ultrasound evaluation of effects of early treatment with metoprolol on myocardial inflammatory cytokine expression in rats with acute myocardial infarction.
Topics: Animals; Cytokines; Inflammation; Male; Metoprolol; Myocardial Infarction; Myocardium; Rats; Rats, S | 2012 |
Gunshot injury of the heart: an unusual cause of acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Adult; Anticoagulants; Aspirin; Coronary Angiography; Coronary Thrombos | 2003 |
[Effect of metoprolol CR/XL on remodeling of the heart and cardiac rhythm disturbances after myocardial infarction in patients with chronic heart failure].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Therapy, Combination; Female; Heart | 2003 |
[Comparative effects of carvedilol and metoprolol in preventing from left ventricular remodeling after acute myocardial infarction in rats].
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Carvedilol; Female; Metoprolol; Myocardial Infarct | 2001 |
[Interrelationship between electrophysiological markers of arrhythmogenicity and psychoemotional status of patients with myocardial infarction].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmi | 2003 |
Selective beta1-blockade attenuates post-infarct remodelling without improvement in myocardial energy metabolism and function in rats with heart failure.
Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Disease Models, Animal; Echocardiography | 2003 |
Comparison of metoprolol with low, middle and high doses of carvedilol in prevention of postinfarction left ventricular remodeling in rats.
Topics: Animals; Carbazoles; Cardiac Volume; Carvedilol; Dose-Response Relationship, Drug; Female; Heart Rat | 2003 |
How should subgroup analyses affect clinical practice? Insights from the Metoprolol Succinate Controlled-Release/Extended-Release Randomized Intervention Trial in Heart Failure (MERIT-HF).
Topics: Adrenergic beta-Antagonists; Black People; Diabetic Angiopathies; Heart Failure; Humans; Hypertensio | 2003 |
Effects of a beta-blocker on ventricular late potentials in patients with acute anterior myocardial infarction receiving successful thrombolytic therapy.
Topics: Adrenergic beta-Antagonists; Adult; Coronary Angiography; Electrocardiography; Female; Heart Ventric | 2004 |
The European Society of Cardiology working group on heart failure: Heart Failure Update 2003.
Topics: Carbazoles; Cardiac Pacing, Artificial; Carvedilol; Eplerenone; Europe; Heart Failure; Humans; Metop | 2003 |
NFATc3-induced reductions in voltage-gated K+ currents after myocardial infarction.
Topics: Action Potentials; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclosporine; DNA | 2004 |
Beneficial effects of chronic pharmacological manipulation of beta-adrenoreceptor subtype signaling in rodent dilated ischemic cardiomyopathy.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonist | 2004 |
[Correction of baroreflex sensitivity impairment and efficacy of prevention of sudden arrhythmic death in patients with postinfarction left ventricular dysfunction].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti | 2004 |
Sudden death after IV metoprolol administration in a patient with cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Alcoholism; Cardiomyopathy, Dilated; Death, Sudden, Cardiac; Ele | 2004 |
[Effects of early treatment with metoprolol on myocardial inflammatory cytokine expression and heart function in rats with acute myocardial infarction].
Topics: Adrenergic beta-Antagonists; Animals; Cytokines; Heart; Immunohistochemistry; Male; Metoprolol; Myoc | 2005 |
Safety and accuracy of multidetector row computed tomography for early assessment of residual stenosis of the infarct-related artery and the number of diseased vessels after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Artifacts; Calcinosis; Comorbidity; Coronary Angiography; Coronar | 2005 |
[Clinical and prognostic value of therapy with contemporary beta-adrenoblockers in patients after myocardial infarction].
Topics: Adrenergic beta-Antagonists; Adult; Benzopyrans; Electrocardiography; Ethanolamines; Female; Humans; | 2005 |
Effect of beta-blockers on cardiac function and calcium handling protein in postinfarction heart failure rats.
Topics: Adrenergic beta-Antagonists; Animals; Calcium-Binding Proteins; Calcium-Transporting ATPases; Carbaz | 2005 |
Beta blockers for elective surgery in elderly patients: population based, retrospective cohort study.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Canada; Elective Surgical Procedures; Female; Hospital | 2005 |
[Muscular mechanisms of lowering of physical working capacity in chronic heart failure and action of beta-adrenoblockers].
Topics: Adrenergic beta-Antagonists; Aged; Chronic Disease; Exercise Test; Female; Heart Rate; Humans; Male; | 2005 |
Something old, something new: beta blockers and clopidogrel in acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; China; Clopidogrel; Drug Therapy, Combination; Humans; Met | 2005 |
Acute myocardial infarction complicated by pulmonary embolism after thrombolytic therapy: problems in clinical management.
Topics: Adrenergic beta-Antagonists; Aged; Electrocardiography; Humans; Immobilization; Male; Metoprolol; My | 2005 |
Acute myocardial infarction in a patient with severe unrecognized mitral stenosis.
Topics: Analgesics; Anti-Arrhythmia Agents; Anticholesteremic Agents; Anticoagulants; Aspirin; Atrial Fibril | 2006 |
Clopidogrel and metoprolol in myocardial infarction.
Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Humans; | 2006 |
Clopidogrel and metoprolol in myocardial infarction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clopidogrel; Gastrointestinal Hemorrhage; Humans; | 2006 |
Clopidogrel and metoprolol in myocardial infarction.
Topics: Adrenergic beta-Antagonists; Clopidogrel; Humans; Metoprolol; Myocardial Infarction; Platelet Aggreg | 2006 |
Pharmacological stimulation of beta2-adrenergic receptors (beta2AR) enhances therapeutic effectiveness of beta1AR blockade in rodent dilated ischemic cardiomyopathy.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 2005 |
[Optimisation of the myocardial infarction pharmacotherapy--important insights from the COMMIT Trial].
Topics: Antihypertensive Agents; Clopidogrel; Humans; Metoprolol; Myocardial Infarction; Platelet Aggregatio | 2006 |
Rationale, design, and organization of the PeriOperative ISchemic Evaluation (POISE) trial: a randomized controlled trial of metoprolol versus placebo in patients undergoing noncardiac surgery.
Topics: Adrenergic beta-Antagonists; Aged; Cardiovascular Diseases; Delayed-Action Preparations; Digestive S | 2006 |
Effects of prolonged metoprolol treatment on neural remodeling and inducible ventricular arrhythmias after myocardial infarction in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Heart Ventricles; Metoprolol; Myocardial | 2007 |
Comparison of pyrroloquinoline quinone and/or metoprolol on myocardial infarct size and mitochondrial damage in a rat model of ischemia/reperfusion injury.
Topics: Adrenergic beta-Antagonists; Animals; Antioxidants; Body Weight; Cardiotonic Agents; Creatine Kinase | 2006 |
Elective surgery days after myocardial infarction: clinical and ethical considerations.
Topics: Adrenergic beta-Antagonists; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; | 2006 |
COMMIT/CCS-2 studies.
Topics: Adrenergic beta-Antagonists; Clopidogrel; Humans; Metoprolol; Myocardial Infarction; Platelet Aggreg | 2006 |
[Effects of atenolol and metoprolol on cardiomyocyte apoptosis and related gene expression after acute myocardial infarction in rats].
Topics: Adrenergic beta-Antagonists; Animals; Apoptosis; Atenolol; bcl-2-Associated X Protein; Female; Metop | 2006 |
Comparison of a beta-blocker and an If current inhibitor in rabbits with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Benzazepines; Blood Flow Velocity; Cardiotonic Agents; | 2006 |
Effects of metoprolol on sympathetic remodeling and electrical remodeling at infarcted border zone after myocardial infarction in rabbits.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Female; GAP-43 Protei | 2007 |
Hymenoptera sting-induced Kounis syndrome: effects of aspirin and beta-blocker administration.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Animals; Anti-Inflammatory Agents, Non-Steroidal | 2007 |
A population-based analysis of the class effect of beta-blockers after myocardial infarction.
Topics: Acebutolol; Adrenergic beta-Antagonists; Aged; Atenolol; Female; Humans; Male; Metoprolol; Myocardia | 2007 |
Protocol implementation in anesthesia: beta-blockade in non-cardiac surgery patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Clinical Protocols; Humans; Intensive C | 2007 |
Sodium-hydrogen exchange inhibition and beta-blockade additively decrease infarct size.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Drug Combinations; Guanidines; Heart; Heart Ventricle | 2007 |
Invited commentary.
Topics: Adrenergic beta-Antagonists; Animals; Drug Combinations; Guanidines; Metoprolol; Myocardial Infarcti | 2007 |
Cardiovascular toxicity due to metoprolol poisoning in a patient with coronary artery disease.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Coronary Artery Disease; Electrocardiog | 2007 |
Early metoprolol administration before coronary reperfusion results in increased myocardial salvage: analysis of ischemic myocardium at risk using cardiac magnetic resonance.
Topics: Animals; Magnetic Resonance Imaging; Metoprolol; Myocardial Infarction; Myocardial Ischemia; Myocard | 2007 |
Effects of metoprolol treatment on a disintegrin metalloproteinase expression and extracellular matrix remodeling after myocardial infarction in rats.
Topics: ADAM Proteins; ADAM17 Protein; Adrenergic beta-Antagonists; Animals; Male; Metoprolol; Myocardial In | 2007 |
Hospitalization rates of generic metoprolol compared with the original beta-blocker in an epidemiological database study.
Topics: Adrenergic beta-Antagonists; Aged; Arrhythmias, Cardiac; Arthritis, Rheumatoid; Databases, Factual; | 2007 |
Death temporally related to the use of a Beta adrenergic receptor antagonist in cocaine associated myocardial infarction.
Topics: Administration, Intranasal; Adrenergic beta-Antagonists; Cause of Death; Cocaine; Cocaine-Related Di | 2007 |
[Effect of chronic myocardial infarction on the distribution of beta-adrenoceptors in heart: experiment with dogs].
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 2007 |
Cardioprotective and survival benefits of long-term combined therapy with beta2 adrenoreceptor (AR) agonist and beta1 AR blocker in dilated cardiomyopathy postmyocardial infarction.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonist | 2008 |
Effect of metoprolol and ivabradine on left ventricular remodelling and Ca2+ handling in the post-infarction rat heart.
Topics: Adrenergic beta-Antagonists; Animals; Benzazepines; Calcium; Disease Models, Animal; Heart Failure; | 2008 |
Beneficial effect of the central nervous system beta-adrenoceptor blockade on the failing heart.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Brain; Disease Models, | 2008 |
Perioperative myocardial infarction after cesarean section in a young woman with hypertrophic obstructive cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; | 2008 |
Regulatory influence of melatonin on collagen accumulation in the infarcted heart scar.
Topics: Animals; Cells, Cultured; Cicatrix; Collagen; Fibroblasts; Gene Expression Regulation; Hydroxyprolin | 2008 |
[Use of beta-adrenergic blocking agents in acute myocardial infarction (author's transl)].
Topics: Acute Disease; Adrenergic beta-Antagonists; Animals; Coronary Circulation; Creatine Kinase; Electroc | 1981 |
Metoprolol after acute myocardial infarction.
Topics: Acute Disease; Humans; Metoprolol; Myocardial Infarction; Propanolamines; Risk | 1981 |
Metoprolol in acute myocardial infarction.
Topics: Humans; Metoprolol; Myocardial Infarction; Propanolamines | 1982 |
Comparative investigation of the effects of metoprolol, propranolol, practolol, and verapamil in the acute phase of experimental myocardial infarction.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel Blockers | 1982 |
Beta-blockers after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Humans; Metoprolol; Myocardial Infarction; Propranolol; Timolol | 1982 |
Acute myocardial infarction: selective or ISA-type beta-adrenoceptor blocking drug?
Topics: Adrenergic beta-Antagonists; Coronary Disease; Humans; Metoprolol; Myocardial Infarction; Pindolol; | 1982 |
Protective effects on isolated hearts with developing infarction: slow channel blockade by diltiazem versus beta-adrenoceptor antagonism by metoprolol.
Topics: Adrenergic beta-Antagonists; Animals; Benzazepines; Calcium Channel Blockers; Cardiac Output; Cardia | 1982 |
Clinical experiences with prenalterol as an antidote to Beta-adrenoceptor blockade.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Anesthesia; Cardiac Catheterizat | 1982 |
Secondary prevention after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Coronary Disease; Humans; Metoprolol; Myocardial Infarction; Prognosis; | 1982 |
[Secondary prevention of myocardial infarct with beta blockers].
Topics: Adrenergic beta-Antagonists; Coronary Circulation; Coronary Disease; Humans; Metoprolol; Myocardial | 1983 |
[Beta-blockers in acute myocardial infarct].
Topics: Adrenergic beta-Antagonists; Blood Pressure; Heart Rate; Humans; Metoprolol; Myocardial Infarction | 1983 |
Relationship between the enzymatically estimated infarct size and clinical findings in acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Creatine Kinase; Follow-Up Studies; Furose | 1984 |
Impaired beta-adrenergic stimulation in the uninvolved ventricle post-acute myocardial infarction: reversible defect due to excessive circulating catecholamine-induced decline in number and affinity of beta-receptors.
Topics: Adenylyl Cyclases; Animals; Catecholamines; Coronary Circulation; Female; Guinea Pigs; Isoproterenol | 1981 |
Cardiac contractile and metabolic effects mediated via the myocardial H2-receptor adenylate cyclase system. Characterization of two new specific H2-receptor agonists, impromidine and dimaprit, in the guinea pig and human myocardium.
Topics: Adenylyl Cyclases; Animals; Cimetidine; Cyclic AMP; Dimaprit; Dose-Response Relationship, Drug; Fema | 1981 |
Correlation between electrocardiographically and enzymatically estimated infarct size and its relation to clinical course in inferior myocardial infarction.
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Double-Blind Method; Electrocardiogr | 1984 |
Comparative effects of propranolol, timolol and metoprolol on myocardial infarct size after experimental coronary artery occlusion.
Topics: Animals; Blood Pressure; Coronary Circulation; Dogs; Fatty Acids, Nonesterified; Female; Heart Rate; | 1984 |
Relationship between electrocardiographically estimated infarct size and clinical findings in anterior myocardial infarction.
Topics: Adult; Aged; Arrhythmias, Cardiac; Electrocardiography; Heart Failure; Humans; Hypotension; Length o | 1984 |
Myocardial infarct size limitation. Principles, problems and possibilities.
Topics: Allopurinol; Animals; Coronary Circulation; Dogs; Flurbiprofen; Humans; Metoprolol; Myocardial Infar | 1984 |
Action of sotalol on potential reentrant pathways and ventricular tachyarrhythmias in conscious dogs in the late postmyocardial infarction phase.
Topics: Action Potentials; Animals; Consciousness; Dogs; Electrocardiography; Heart Conduction System; Metop | 1983 |
Treatment and prophylaxis of ventricular arrhythmias in acute myocardial infarction.
Topics: Arrhythmias, Cardiac; Humans; Lidocaine; Metoprolol; Myocardial Infarction; Resuscitation; Time Fact | 1983 |
Failure of pindolol and metoprolol to reduce the size of non-reperfused infarcts in dogs using area at risk techniques.
Topics: Animals; Coronary Circulation; Dogs; Hemodynamics; Metoprolol; Myocardial Infarction; Pindolol; Risk | 1984 |
Göteborg Metoprolol Trial: effects on arrhythmias.
Topics: Adult; Aged; Arrhythmias, Cardiac; Clinical Trials as Topic; Double-Blind Method; Female; Heart Arre | 1984 |
Göteborg Metoprolol Trial: clinical observations.
Topics: Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Furosemide; Heart Failure; Heart Rate | 1984 |
Göteborg Metoprolol Trial: tolerance.
Topics: Administration, Oral; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; | 1984 |
Göteborg Metoprolol Trial: mortality and causes of death.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Heart Failure; Hea | 1984 |
Effect of metoprolol on chest pain in acute myocardial infarction.
Topics: Coronary Circulation; Humans; Metoprolol; Myocardial Infarction | 1984 |
Cardiac safety of acute beta blockade: intrinsic sympathomimetic activity is superior to beta-1 selectivity.
Topics: Adult; Aged; Angina Pectoris; Drug Evaluation; Echocardiography; Exercise Test; Female; Heart Ventri | 1982 |
Central and peripheral haemodynamic effects of prenalterol in patients with coronary heart disease.
Topics: Blood Pressure; Cardiac Output; Female; Forearm; Heart; Heart Rate; Hemodynamics; Humans; Injections | 1981 |
[Prajmalium bitartrate in hyperkinetic ventricular arrhythmias in infarct patients during rehabilitation].
Topics: Adult; Aged; Ajmaline; Ambulatory Care; Amiodarone; Arrhythmias, Cardiac; Drug Therapy, Combination; | 1981 |
[Metoprolol in the treatment of myocardial infarct in the acute stage].
Topics: Acute Disease; Adult; Female; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanol | 1981 |
Intravenous metoprolol preceding thrombolysis in acute thrombotic myocardial infarction in the dog; effects on infarct size, myocardial blood flow, and left ventricular function.
Topics: Animals; Cardiac Output; Collateral Circulation; Coronary Thrombosis; Dogs; Fibrinolytic Agents; Hea | 1994 |
Elevated plasma atrial natriuretic peptide concentrations in hypertensive patients with acute myocardial infarction.
Topics: Acebutolol; Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Cardiac Output, Low; Creatine Ki | 1995 |
[Beta-receptor blockers after revascularization in coronary sclerosis].
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Coronary Artery Bypass; Coronary Diseas | 1995 |
Failure of intravenous metoprolol to limit acute myocardial infarct size in a nonreperfused porcine model.
Topics: Animals; Coronary Vessels; Electrocardiography; Hemodynamics; Infusions, Intravenous; Metoprolol; My | 1995 |
Impact of clinical trials on the use of beta blockers after acute myocardial infarction and its relation to other risk indicators for death and 1-year mortality rate.
Topics: Adrenergic beta-Antagonists; Aged; Clinical Trials as Topic; Female; Humans; Male; Metoprolol; Middl | 1994 |
Effects of oral pretreatment with metoprolol on left ventricular wall motion, infarct size, hemodynamics, and regional myocardial blood flow in anesthetized dogs during thrombotic coronary artery occlusion and reperfusion.
Topics: Administration, Oral; Animals; Coronary Circulation; Coronary Thrombosis; Coronary Vessels; Disease | 1994 |
Angiotensin-converting enzyme inhibition and beta-adrenoceptor blockade regress established ventricular remodeling in a canine model of discrete myocardial damage.
Topics: Animals; Captopril; Dogs; Hemodynamics; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; M | 1994 |
Effects of beta blockers (atenolol or metoprolol) on heart rate variability after acute myocardial infarction.
Topics: Atenolol; Circadian Rhythm; Echocardiography; Electrocardiography, Ambulatory; Exercise Test; Heart | 1994 |
Local beta-adrenergic blockade does not reduce infarct size after coronary occlusion and reperfusion: a study of coronary venous retroinfusion of metoprolol.
Topics: Adrenergic beta-Antagonists; Animals; Coronary Vessels; Female; Hemodynamics; Infusions, Intravenous | 1993 |
Effects of metoprolol on left ventricular function in rats with myocardial infarction.
Topics: Animals; Blood Pressure; Coronary Vessels; Diastole; Disease Models, Animal; Dose-Response Relations | 1994 |
Ten year mortality in relation to original size of myocardial infarct: results from the Gothenburg metoprolol study.
Topics: Adult; Aged; Angina Pectoris; Diabetes Complications; Female; Follow-Up Studies; Humans; Hypertensio | 1994 |
Effects of metoprolol on early infarct expansion after acute myocardial infarction.
Topics: Animals; Cardiac Volume; Female; Heart Ventricles; Hemodynamics; Metoprolol; Myocardial Infarction; | 1994 |
Occurrence of hypotension during streptokinase infusion in suspected acute myocardial infarction, and its relation to prognosis and metoprolol therapy.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Female; Humans; Hypotension; Male; Metoprolol; Middl | 1993 |
The effect of beta-blockade therapy on the response to exercise training in postmyocardial infarction patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Electrocardiography; Exercise Therapy; Female; Hemodynamic | 1995 |
Converting enzyme inhibition, heart rate variability, and myocardial infarction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Heart Rate; Humans; Isoquinolines; | 1996 |
Correlation between time-domain measures of heart rate variability and scatterplots in patients with healed myocardial infarcts and the influence of metoprolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Electrocardiography; Female; Heart Rate; Humans; Male; Met | 1997 |
Effects and pharmacokinetics of high dose metoprolol on chest pain in patients with suspected or definite acute myocardial infarction.
Topics: Aged; Aged, 80 and over; Analgesia; Antihypertensive Agents; Blood Pressure; Catecholamines; Chest P | 1997 |
Comparative efficacy of a DA2/alpha2 agonist and a beta-blocker in reducing adrenergic drive and cardiac fibrosis in an experimental model of left ventricular dysfunction after coronary artery occlusion.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Catechol | 1998 |
Effect of atenolol or metoprolol on waking hour dynamics of the QT interval in myocardial infarction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Case-Control Studies; Circadian Rhythm; Electroc | 1998 |
Comparison of metoprolol and carvedilol pharmacology and cardioprotection in rabbit ischemia and reperfusion model.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Blood Pressure; Ca | 1998 |
Influence of an early adrenergic blockade on thrombotic infarct size and myocardial metabolism.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Blood Glucose; Dogs; Fatty Acids, Nonesterified; Fe | 1998 |
Intravenous beta blockade in acute myocardial infarction. Case for intravenous beta blockade for patients given thrombolysis is still uncertain.
Topics: Adrenergic beta-Antagonists; Chest Pain; Humans; Metoprolol; Myocardial Infarction; Recurrence; Thro | 1999 |
Similar risk reduction of death of extended-release metoprolol once daily and immediate-release metoprolol twice daily during 5 years after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anthropometry; Delayed-Action Preparati | 1999 |
Age- and gender-related use of low-dose drug therapy: the need to manufacture low-dose therapy and evaluate the minimum effective dose.
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Confide | 1999 |
[The effect of a combination ACE inhibitor and beta-blockers in acute myocardial infarct].
Topics: Acute Disease; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dru | 1999 |
Beta-blockade improves adjacent regional sympathetic innervation during postinfarction remodeling.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Female; Heart Conduc | 1999 |
[Ticlopidine-induced cholestasis].
Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Chemical and Drug Induced Liver Injury; Cholestas | 1999 |
Effects of metoprolol and ramipril on action potentials after myocardial infarction in rats.
Topics: Action Potentials; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; E | 2000 |
Minimum risk weights for comparing treatments in stratified binomial trials.
Topics: Anti-Arrhythmia Agents; Bias; Data Interpretation, Statistical; Humans; Metoprolol; Myocardial Infar | 2000 |
beta-adrenergic blockade in developing heart failure: effects on myocardial inflammatory cytokines, nitric oxide, and remodeling.
Topics: Adrenergic beta-Antagonists; Animals; Cytokines; Gene Expression; Interleukin-1; Interleukin-6; Isop | 2000 |
Retrospective analysis showing less cardiac events in post-myocardial infarction patients treated with metoprolol. Secondary Prevention Group.
Topics: Adrenergic beta-Antagonists; Aged; Death, Sudden, Cardiac; Drug Evaluation; Female; Heart Failure; H | 2000 |
Effect of carvedilol in comparison with metoprolol on myocardial collagen postinfarction.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Carbazoles; Carvedil | 2000 |
Beta-blockade for patients with heart failure.
Topics: Adrenergic beta-Antagonists; Clinical Protocols; Clinical Trials as Topic; Ethics, Medical; Heart Fa | 2000 |
Simultaneous testing strategy for comparing two treatments in a stratified binomial trial.
Topics: Adrenergic beta-Antagonists; Aged; Binomial Distribution; Data Interpretation, Statistical; Humans; | 2000 |
[Myocardial infarction, pregnancy and anesthesia].
Topics: Adrenergic beta-Antagonists; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesic | 2000 |
Selective beta(1)-blockade improves cardiac bioenergetics and function and decreases neuroendocrine activation in rats during early postinfarct remodeling.
Topics: Adrenergic beta-Antagonists; Animals; Body Weight; Catecholamines; Echocardiography; Energy Metaboli | 2001 |
Comparative effects of three beta blockers (atenolol, metoprolol, and propranolol) on survival after acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Baltimore; Female; Humans; Male; Medical Records; Metop | 2001 |
Combined treatment with ramipril and metoprolol prevents changes in the creatine kinase isoenzyme system and improves hemodynamic function in rat hearts after myocardial infarction.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomegaly; Creati | 2000 |
Angerlike behavioral state potentiates myocardial ischemia-induced T-wave alternans in canines.
Topics: Adrenergic beta-Antagonists; Anger; Animals; Arousal; Blood Pressure; Death, Sudden, Cardiac; Diseas | 2001 |
Metoprolol attenuates postischemic depressed myocardial function in papillary muscles isolated from normal and postinfarction rat hearts.
Topics: Adrenergic beta-Antagonists; Animals; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPase | 2001 |
Are all beta-blockers equally effective in reducing mortality after acute myocardial infarction (AMI)?
Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Drug Costs; Evidence-Based Medicine; Female; Humans; Ma | 2001 |
Cocaine use and acute coronary syndromes.
Topics: Adrenergic beta-Antagonists; Cocaine; Humans; Metoprolol; Myocardial Infarction; Ventricular Functio | 2001 |
Growth hormone alone or combined with metoprolol preserves cardiac function after myocardial infarction in rats.
Topics: Adrenergic beta-Antagonists; Aneurysm; Animals; Body Weight; Drug Therapy, Combination; Echocardiogr | 2001 |
Do beta-adrenergic blocking agents increase coronary flow reserve?
Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon, Coronary; Blood Flow Velocity; Coronary Cir | 2001 |
Myocardial oxidative metabolism in remote normal regions in the left ventricles with remodeling after myocardial infarction: effect of beta-adrenoceptor blockers.
Topics: Acetates; Adrenergic beta-Antagonists; Atenolol; Carbon Radioisotopes; Cardiac Catheterization; Case | 2002 |
Haemodynamic effects of a new beta 1-receptor agonist in acute myocardial infarction. A useful antidote to unwanted cardiac effects of beta-blocking agents.
Topics: Acute Disease; Adrenergic beta-Agonists; Adult; Aged; Heart; Heart Rate; Hemodynamics; Humans; Metop | 1979 |
Beta-blocker withdrawal syndrome?
Topics: Angina Pectoris; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Recur | 1979 |
[Effects of acute beta-adrenoceptor blockage (metoprolol i.v.) on plasma norepinephrine concentration and hemodynamics in postmyocardial infarction patients].
Topics: Adult; Angiography; Blood Pressure; Coronary Vessels; Heart Rate; Heart Ventricles; Hemodynamics; Hu | 1979 |
[Cardioselective beta blocker methoprolol evaluation in patients suffering from myocardial infarction (author's transl)].
Topics: Acute Disease; Adult; Aged; Drug Evaluation; Humans; Metoprolol; Middle Aged; Myocardial Infarction; | 1977 |
[Treatment of acute myocardial infarction with metoprolol (author's transl)].
Topics: Acute Disease; Adult; Aged; Blood Pressure; Cardiac Output; Female; Heart Rate; Humans; Male; Metopr | 1978 |
Hemodynamic effects of the cardioselective beta-blocking agent metoprolol in acute myocardial infarction. A 24-hour catheterization study.
Topics: Acute Disease; Aged; Blood Pressure; Cardiac Catheterization; Cardiac Output; Drug Evaluation; Heart | 1978 |
Safety of combined intravenous beta-adrenergic blockade (atenolol or metoprolol) and thrombolytic therapy in acute myocardial infarction.
Topics: Administration, Oral; Adult; Aspirin; Atenolol; Combined Modality Therapy; Female; Humans; Infusions | 1992 |
A possible acute MI: what location and type?
Topics: Aspirin; Coronary Angiography; Coronary Disease; Drug Therapy, Combination; Electrocardiography; Eme | 1991 |
Effects of beta-adrenergic blockade in acute myocardial infarction: evaluation by radionuclide ventriculography.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Depression, Chemical; Gated Blood-Pool Imaging; Hemodynami | 1990 |
Incidence of sudden cardiac death associated with coronary artery occlusion in dogs with hypertension and left ventricular hypertrophy is reduced by chronic beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Death, S | 1990 |
Comparison of angiographic methods for the assessment of the extent of experimental anterior myocardial infarction in dog hearts.
Topics: Adrenergic beta-Antagonists; Angiography; Angiography, Digital Subtraction; Animals; Cineangiography | 1990 |
Metoprolol for myocardial infarction.
Topics: Humans; Injections, Intravenous; Metoprolol; Myocardial Infarction | 1991 |
Thoracic epidural anesthesia improves global and regional left ventricular function during stress-induced myocardial ischemia in patients with coronary artery disease.
Topics: Aged; Analgesia, Epidural; Bupivacaine; Coronary Disease; Exercise Test; Female; Hemodynamics; Human | 1990 |
The Physician's Health Study. A neurologist's concern.
Topics: Aspirin; Cerebrovascular Disorders; Cohort Studies; Follow-Up Studies; Humans; Male; Metoprolol; Myo | 1990 |
Effects of thoracic epidural anaesthesia on central haemodynamics compared to cardiac beta adrenoceptor blockade in conscious rats with acute myocardial infarction.
Topics: Anesthesia, Epidural; Animals; Blood Pressure; Bupivacaine; Cardiac Output; Consciousness; Heart Rat | 1990 |
Inducible monomorphic sustained ventricular tachycardia in the conscious pig.
Topics: Animals; Coronary Vessels; Disease Models, Animal; Heart Ventricles; Hemodynamics; Lidocaine; Ligati | 1990 |
Associated reactions during and immediately after rtPA infusion.
Topics: Arrhythmias, Cardiac; Drug Hypersensitivity; Drug Therapy, Combination; Emergencies; Hemorrhage; Hum | 1989 |
Thrombolysis in myocardial infarction (TIMI) phase II trial.
Topics: Drug Evaluation; Humans; Metoprolol; Myocardial Infarction; Research Design; Tissue Plasminogen Acti | 1989 |
Coronary reperfusion by thrombolysis and early beta-adrenergic blockade in acute experimental myocardial infarction.
Topics: Animals; Dogs; Female; Male; Metoprolol; Myocardial Contraction; Myocardial Infarction; Myocardial R | 1989 |
Effects of intravenous metoprolol on global and regional left ventricular function after coronary arterial reperfusion in acute myocardial infarction.
Topics: Adult; Angioplasty, Balloon; Blood Pressure; Cardiac Output; Female; Heart; Heart Rate; Humans; Infu | 1989 |
Impending myocardial infarction in a patient with marked left ventricular hypertrophy and normal coronary arteriogram--a case report.
Topics: Angiocardiography; Angiography; Cardiomegaly; Coronary Angiography; Echocardiography; Electrocardiog | 1989 |
Influence of beta-blockade on ejection fraction, ANP, and cGMP in patients after myocardial infarction.
Topics: Atrial Natriuretic Factor; Cyclic GMP; Humans; Metoprolol; Myocardial Infarction; Stroke Volume | 1989 |
[Multicenter clinical trial on the prevention of sudden death after myocardial infarction by the use of anti-arrhythmia agents. Investigator Group of the Spanish Study on Sudden Death].
Topics: Amiodarone; Arrhythmias, Cardiac; Captopril; Death, Sudden; Humans; Metoprolol; Multicenter Studies | 1989 |
Identification of Patients at Low Risk of Dying After Acute Myocardial Infarction, By Simple Clinical and Submaximal Exercise Test Criteria.
Topics: Humans; Metoprolol; Myocardial Infarction | 1989 |
Quality of life five years after myocardial infarction.
Topics: Angina Pectoris; Anxiety Disorders; Dyspnea; Female; Follow-Up Studies; Humans; Male; Metoprolol; My | 1989 |
Hemodynamic effects of intravenous metoprolol in acute myocardial infarction: the role of anatomic subsets in predicting patient response.
Topics: Administration, Oral; Cardiac Catheterization; Diastole; Drug Evaluation; Female; Heart Ventricles; | 1988 |
Exercise training during chronic beta blockade in cardiovascular disease.
Topics: Adrenergic beta-Antagonists; Atenolol; Coronary Artery Bypass; Female; Heart Rate; Humans; Male; Met | 1985 |
Acute myocardial infarction in post infarct patient possibly through beta blocker-induced coronary artery spasm.
Topics: Adrenergic beta-Antagonists; Cardiac Catheterization; Coronary Vasospasm; Electrocardiography; Ergon | 1987 |
Effect of beta-blockers on the relation between QT-interval and heart rate in exercise ECG.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; | 1987 |
The use of beta-adrenergic blocking agents, i.v. nitrates and calcium channel blocking agents following acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Humans; Infusions, Intravenous; Metoprolol; M | 1988 |
Effect of intravenous metoprolol on left ventricular performance in Q-wave acute myocardial infarction.
Topics: Adult; Aged; Electrocardiography; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Metopr | 1989 |
A comparison of the effects of combined or separate alpha- and beta-blockade in the treatment of hypertension in the acute stage of myocardial infarction.
Topics: Adult; Aged; Blood Pressure; Carbon Dioxide; Female; Heart Rate; Humans; Hypertension; Infusions, Pa | 1986 |
Reduction in infarct size and enhanced recovery of systolic function after coronary thrombolysis with tissue-type plasminogen activator combined with beta-adrenergic blockade with metoprolol.
Topics: Animals; Coronary Disease; Coronary Thrombosis; Dogs; Drug Evaluation, Preclinical; Drug Therapy, Co | 1987 |
[Metoprolol and nitroglycerin administered intravenously in acute myocardial infarction].
Topics: Aged; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Metoprolol; Middle Aged | 1987 |
Comparison of different pharmacological interventions on enzymatic parameters during acute myocardial infarction.
Topics: Adult; Aged; Clinical Enzyme Tests; Creatine Kinase; Dipyridamole; Female; Heart; Heparin; Humans; I | 1987 |
5-year mortality rate in patients with suspected acute myocardial infarction in relation to early diagnosis.
Topics: Double-Blind Method; Humans; Metoprolol; Myocardial Infarction; Prospective Studies; Random Allocati | 1988 |
Comparative investigations on the antiarrhythmic and electrophysiologic effects of class I-IV antiarrhythmic agents following acute coronary artery occlusion.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Dogs; Female; Heart Conduct | 1987 |
The hemodynamics of beta-blockade in patients undergoing abdominal aortic aneurysm repair.
Topics: Aged; Aorta, Abdominal; Aortic Aneurysm; Female; Hemodynamics; Humans; Intraoperative Care; Male; Me | 1987 |
Effects of chronic metoprolol treatment on glucose tolerance after myocardial infarction.
Topics: Glucose Tolerance Test; Humans; Metoprolol; Myocardial Infarction | 1987 |
Natural evolution of left ventricular haemodynamics following uncomplicated acute myocardial infarction.
Topics: Aged; Blood Pressure; Cardiac Catheterization; Cardiac Output; Drug Therapy, Combination; Electrocar | 1986 |
Effect of antiarrhythmic therapy on delayed potentials detected by the signal-averaged electrocardiogram in patients with ventricular tachycardia after acute myocardial infarction.
Topics: Action Potentials; Adult; Aged; Anti-Arrhythmia Agents; Electrocardiography; Heart Ventricles; Human | 1986 |
[Prevention of reinfarction with beta blockaders: socioeconomic effect of metoprolol treatment].
Topics: Aged; Costs and Cost Analysis; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Recurre | 1986 |
Metoprolol in acute myocardial infarction. A pharmacokinetic and pharmacodynamic study.
Topics: Administration, Oral; Aged; Blood Pressure; Female; Heart Rate; Humans; Infusions, Intravenous; Kine | 1986 |
Autonomic control of ventricular tachycardia: direct effects of beta-adrenergic blockade in 24 hour old canine myocardial infarction.
Topics: Animals; Coronary Vessels; Dogs; Female; Heart Conduction System; Hemodynamics; Injections, Intra-Ar | 1987 |
Relationship between different enzymatic estimations of the infarct size.
Topics: Adult; Aged; Aspartate Aminotransferases; Creatine Kinase; Double-Blind Method; Humans; Isoenzymes; | 1985 |
IV metoprolol in RV-AMI.
Topics: Aged; Female; Humans; Infusions, Parenteral; Metoprolol; Myocardial Infarction | 1986 |
Intravenous beta blockade in acute myocardial infarction.
Topics: Humans; Infusions, Parenteral; Metoprolol; Myocardial Infarction | 1985 |
The relationship between the electrocardiographically estimated infarct size and 1- and 2-year survival in acute myocardial infarction.
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Electrocardiography; Humans; Metopro | 1985 |
Effects of a combination of metoprolol and dazmegrel on myocardial infarct size in rats.
Topics: Animals; Coronary Disease; Drug Therapy, Combination; Imidazoles; Male; Metoprolol; Myocardial Infar | 1985 |