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metoprolol and Cardiovascular Pregnancy Complications

metoprolol has been researched along with Cardiovascular Pregnancy Complications in 42 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Research Excerpts

ExcerptRelevanceReference
"To compare the effects of treatment with nicardipine and metoprolol in patients with hypertension during pregnancy."9.07Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial. ( Carbonne, B; Jannet, D; Milliez, J; Sebban, E, 1994)
"The plasma drug concentration-effect relationship after an oral dose of 100 mg metoprolol has been studied in 8 women in the third trimester of a pregnancy complicated by hypertension."9.07Plasma concentration-effect relationship of metoprolol during and after pregnancy. ( Högstedt, S; Rane, A, 1993)
"In an open, controlled trial, treatment with a combination of metoprolol and hydralazine was compared with non-pharmacological management of mild and moderate hypertension in pregnancy."9.05A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy. ( Axelsson, O; Högstedt, S; Lindberg, BS; Lindeberg, S; Lindmark, G; Rane, A; Sandström, B, 1985)
"Methyldopa and amlodipine are associated with the least side effects in pregnant women treated for chronic hypertension."7.96The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension. ( Ghafarzadeh, M; Namdari, P; Shakarami, A; Yari, F, 2020)
"Five women who developed hypertension during pregnancy received metoprolol, 10 mg iv; 3 days later they received metoprolol, 100 mg by mouth."7.67Pregnancy-induced increase in metoprolol metabolism. ( Högstedt, S; Lindberg, B; Peng, DR; Rane, A; Regårdh, CG, 1985)
"To compare the effects of treatment with nicardipine and metoprolol in patients with hypertension during pregnancy."5.07Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial. ( Carbonne, B; Jannet, D; Milliez, J; Sebban, E, 1994)
"The plasma drug concentration-effect relationship after an oral dose of 100 mg metoprolol has been studied in 8 women in the third trimester of a pregnancy complicated by hypertension."5.07Plasma concentration-effect relationship of metoprolol during and after pregnancy. ( Högstedt, S; Rane, A, 1993)
"In an open, controlled trial, treatment with a combination of metoprolol and hydralazine was compared with non-pharmacological management of mild and moderate hypertension in pregnancy."5.05A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy. ( Axelsson, O; Högstedt, S; Lindberg, BS; Lindeberg, S; Lindmark, G; Rane, A; Sandström, B, 1985)
"Methyldopa and amlodipine are associated with the least side effects in pregnant women treated for chronic hypertension."3.96The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension. ( Ghafarzadeh, M; Namdari, P; Shakarami, A; Yari, F, 2020)
"Our findings suggest that neonates born to mothers exposed to β blockers in late pregnancy, including labetalol, are at elevated risk for neonatal hypoglycemia and bradycardia."3.83Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia. ( Bateman, BT; Desai, RJ; Fischer, MA; Hernandez-Diaz, S; Huybrechts, KF; Maeda, A; Mogun, H; Patorno, E; Seely, EW, 2016)
"The transfer of atenolol and metoprolol to human breast milk was studied in 7 lactating women with hypertension."3.67Atenolol and metoprolol. A comparison of their excretion into human breast milk. ( Kulas, J; Lunell, NO; Rane, A; Rosing, U; Stéen, B, 1984)
"Seven women were treated with metoprolol 50-100 mg twice daily for hypertension in pregnancy."3.67Disposition of the adrenergic blocker metoprolol and its metabolite OH-metoprolol in maternal plasma, amniotic fluid and capillary blood of the neonate. ( Lindeberg, S; Lundborg, P; Regårdh, CG; Sandström, B, 1987)
"Five women who developed hypertension during pregnancy received metoprolol, 10 mg iv; 3 days later they received metoprolol, 100 mg by mouth."3.67Pregnancy-induced increase in metoprolol metabolism. ( Högstedt, S; Lindberg, B; Peng, DR; Rane, A; Regårdh, CG, 1985)
"The incidence of cardiac arrhythmias is estimated et 1."2.49[Electrical cardioversion in the treatment of cardiac arrhythmias during pregnancy--case report and review of literature]. ( Gałczyński, K; Kimber-Trojnar, Z; Kudlicki, J; Leszczyńska-Gorzelak, B; Marciniak, B; Oleszczukz, J, 2013)
"During evaluation for palpitations, presyncope, or syncope, seven pregnant women had documented ventricular tachycardia."2.38New-onset ventricular tachycardia during pregnancy. ( Allen, B; Brodsky, M; Doria, R; Sada, M; Sato, D; Thomas, G, 1992)
"Supraventricular tachycardia is uncommon in pregnancy."1.40Management of labour and delivery in a woman with refractory supraventricular tachycardia. ( Dennis, AT; Gerstman, MD, 2014)
"Women with persistent atrial fibrillation require anticoagulation and rate control, as well as fetal growth surveillance and antenatal testing."1.37Atrial fibrillation in pregnancy. ( Dahlke, LJ; DiCarlo-Meacham, LA, 2011)
"Takotsubo cardiomyopathy is a cardiac condition associated with the acute onset of chest pain, abnormalities in cardiac enzymes and electrocardiogram, and a distinct pattern of left ventricular dysfunction on echocardiography."1.35Takotsubo cardiomyopathy in pregnancy. ( Brezina, P; Isler, CM, 2008)
"Myocardial infarction is rare during pregnancy."1.31[Myocardial infarction, pregnancy and anesthesia]. ( Diar, N; Rezig, K; Walcker, JL, 2000)

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199021 (50.00)18.7374
1990's5 (11.90)18.2507
2000's4 (9.52)29.6817
2010's8 (19.05)24.3611
2020's4 (9.52)2.80

Authors

AuthorsStudies
Juusela, A1
Nazir, M1
Gimovsky, M1
Ghafarzadeh, M1
Shakarami, A1
Yari, F1
Namdari, P1
Chuzi, S1
Eucalitto, P1
Yee, LM1
Aurora, L1
Nona, P1
Ananthasubramaniam, K1
Duan, L1
Ng, A1
Chen, W1
Spencer, HT1
Nguyen, J1
Shen, AY1
Lee, MS1
Gałczyński, K1
Marciniak, B1
Kudlicki, J1
Kimber-Trojnar, Z1
Leszczyńska-Gorzelak, B1
Oleszczukz, J1
Dennis, AT1
Gerstman, MD1
Bateman, BT1
Patorno, E1
Desai, RJ1
Seely, EW1
Mogun, H1
Maeda, A1
Fischer, MA1
Hernandez-Diaz, S1
Huybrechts, KF1
Brezina, P1
Isler, CM1
Bernardon, M1
Limone, A1
Businelli, C1
Maso, GP1
Piccoli, M1
Alberico, S1
Cacciotti, L1
Camastra, GS1
Ansalone, G1
DiCarlo-Meacham, LA1
Dahlke, LJ1
Norrad, RS1
Salehian, O1
Haas, DM1
DʼAlton, M1
Prochaczek, F1
Winiarska, H1
Gałecka, J1
Moses, JW1
Borer, JS1
Sandström, B9
Lindeberg, S6
Lundborg, P5
Regårdh, CG5
Werner, O1
Finnström, O1
Ezitis, J1
Rydén, G2
Wichman, K2
Hammerle, AF1
Karlberg, BE1
Kulas, J1
Lunell, NO1
Rosing, U1
Stéen, B1
Rane, A4
Agren, G1
Ervik, M1
Jannet, D1
Carbonne, B1
Sebban, E1
Milliez, J1
Högstedt, S3
Rezig, K1
Diar, N1
Walcker, JL1
Brodsky, M1
Doria, R1
Allen, B1
Sato, D1
Thomas, G1
Sada, M1
Tai, YT1
Lo, CW1
Chow, WH1
Cheng, CH1
Resch, BA1
Molnár, GB1
Papp, G1
Lechner, W1
Artner-Dworzak, E1
Heim, K1
Marth, C1
Puschendorf, B1
Kawecka-Jaszcz, K1
Skoczeń, M1
Holm, B1
Popitz-Bergez, F1
Datta, S1
Ostheimer, GW1
Olofsson, P1
Montan, S1
Sartor, G1
Sjöberg, NO1
Suonio, S1
Saarikoski, S1
Tahvanainen, K1
Pääkkönen, A1
Olkkonen, H1
Axelsson, O1
Lindmark, G1
Lindberg, BS1
Lindberg, B1
Peng, DR1

Reviews

4 reviews available for metoprolol and Cardiovascular Pregnancy Complications

ArticleYear
[Electrical cardioversion in the treatment of cardiac arrhythmias during pregnancy--case report and review of literature].
    Ginekologia polska, 2013, Volume: 84, Issue:10

    Topics: Adult; Anti-Arrhythmia Agents; Anticoagulants; Arrhythmias, Cardiac; Digoxin; Electric Countershock;

2013
Beta-adrenergic antagonists in the treatment of patients with heart disease.
    Disease-a-month : DM, 1981, Volume: 27, Issue:9

    Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca

1981
New-onset ventricular tachycardia during pregnancy.
    American heart journal, 1992, Volume: 123, Issue:4 Pt 1

    Topics: Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Exercise Test; Female; Follo

1992
[Beta-blockaders in the treatment of hypertension in pregnancy].
    Kardiologia polska, 1985, Volume: 28, Issue:5

    Topics: Adrenergic beta-Antagonists; Atenolol; Drug Evaluation; Female; Humans; Hypertension; Metoprolol; Ox

1985

Trials

6 trials available for metoprolol and Cardiovascular Pregnancy Complications

ArticleYear
Neonatal effects of beta-blocking drugs in pregnancy.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Adrenergic beta-Antagonists; Apgar Score; Birth Weight; Carbon Dioxide; Cephalometry; Clinical Trial

1984
A placebo controlled trial of metoprolol in the treatment of hypertension in pregnancy.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1984, Volume: 169

    Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Embryonic and Fetal Development; Female; Human

1984
Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial.
    Obstetrics and gynecology, 1994, Volume: 84, Issue:3

    Topics: Adult; Birth Weight; Blood Pressure; Cesarean Section; Drug Administration Schedule; Female; Humans;

1994
Plasma concentration-effect relationship of metoprolol during and after pregnancy.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:3

    Topics: Adult; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Metoprolol; Ph

1993
Effects of beta 1-adrenoceptor blockade in the treatment of hypertension during pregnancy in diabetic women.
    Acta medica Scandinavica, 1986, Volume: 220, Issue:4

    Topics: Adult; Atenolol; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertensi

1986
A prospective controlled trial of metoprolol-hydralazine treatment in hypertension during pregnancy.
    Acta obstetricia et gynecologica Scandinavica, 1985, Volume: 64, Issue:6

    Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Female; Fetus; Gestational Age; Humans;

1985

Other Studies

32 other studies available for metoprolol and Cardiovascular Pregnancy Complications

ArticleYear
Two cases of coronavirus 2019-related cardiomyopathy in pregnancy.
    American journal of obstetrics & gynecology MFM, 2020, Volume: 2, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Antibodies, Monoclonal, Humanized; Anticonvulsants; Blood Gas Analysi

2020
The comparison of side effects of methyldopa, amlodipine, and metoprolol in pregnant women with chronic hypertension.
    Hypertension in pregnancy, 2020, Volume: 39, Issue:3

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Incidence;

2020
A Pregnant Woman With Shortness of Breath.
    JAMA cardiology, 2021, 01-01, Volume: 6, Issue:1

    Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Anticoagulants; Cesarean Section; Dyspnea; Echocardio

2021
A Pregnant Patient with Elevated Heart Rate.
    The American journal of medicine, 2021, Volume: 134, Issue:5

    Topics: Anti-Arrhythmia Agents; Female; Fluid Therapy; Heart Rate; Humans; Metoprolol; Pregnancy; Pregnancy

2021
β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies.
    JAMA internal medicine, 2017, 06-01, Volume: 177, Issue:6

    Topics: Adrenergic beta-Antagonists; Age Factors; Arrhythmias, Cardiac; Atenolol; Body Mass Index; Californi

2017
Management of labour and delivery in a woman with refractory supraventricular tachycardia.
    International journal of obstetric anesthesia, 2014, Volume: 23, Issue:1

    Topics: Adult; Amides; Amnion; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Epidural; Anes

2014
Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia.
    Pediatrics, 2016, Volume: 138, Issue:3

    Topics: Adrenergic beta-Antagonists; Atenolol; Bradycardia; Cohort Studies; Female; Humans; Hypertension; Hy

2016
Takotsubo cardiomyopathy in pregnancy.
    Obstetrics and gynecology, 2008, Volume: 112, Issue:2 Pt 2

    Topics: Adrenergic beta-Antagonists; Adult; Echocardiography; Electrocardiography; Female; Humans; Metoprolo

2008
Acute myocardial infarction in pregnancy.
    Minerva ginecologica, 2008, Volume: 60, Issue:6

    Topics: Adult; Angioplasty, Balloon, Coronary; Anticoagulants; Apgar Score; Aspirin; Cesarean Section; Coron

2008
Atrial fibrillation in a pregnant woman with a normal heart.
    Internal and emergency medicine, 2010, Volume: 5, Issue:1

    Topics: Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Cesarean Section; Electrocardiography; Female; H

2010
Atrial fibrillation in pregnancy.
    Obstetrics and gynecology, 2011, Volume: 117, Issue:2 Pt 2

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Electrocardiography; Female; Hum

2011
Management of severe mitral stenosis during pregnancy.
    Circulation, 2011, Dec-13, Volume: 124, Issue:24

    Topics: Adult; Anticoagulants; Catheterization; Dalteparin; Drug Therapy, Combination; Echocardiography, Dop

2011
Pharmacogenetics and other reasons why drugs can fail in pregnancy: higher dose or different drug?
    Obstetrics and gynecology, 2012, Volume: 120, Issue:5

    Topics: Antihypertensive Agents; Chronic Disease; Cytochrome P-450 CYP2D6; Drug Substitution; Female; Humans

2012
[Termination of atrio-ventricular reentrant tachycardia in a pregnant woman using transoesophageal atrial pacing and pharmacotherapy].
    Kardiologia polska, 2008, Volume: 66, Issue:2

    Topics: Adult; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Female; Humans; Metoprolol; Pregnancy; Pr

2008
Adrenergic beta-receptor blockers in hypertension of pregnancy.
    Clinical and experimental hypertension. Part B, Hypertension in pregnancy, 1982, Volume: 1, Issue:1

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Birth Weight; Blood Pressure; Delivery, Obstetric; F

1982
Disposition of the adrenergic blocker metoprolol in the late pregnant women, the amniotic fluid, the cord blood and the neonate.
    Clinical and experimental hypertension. Part B, Hypertension in pregnancy, 1983, Volume: 2, Issue:1

    Topics: Adrenergic beta-Antagonists; Amniotic Fluid; Female; Fetal Blood; Humans; Hypertension; Infant, Newb

1983
Some notes on the hormonal and haemodynamic responses to stressful stimuli.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Anesthesia, Epidural; Anesthesia, General;

1984
Clinical trials of adrenergic antagonists in pregnancy hypertension.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Apgar Score; Birth Weight; Female; Fetal Growt

1984
[New aspects in the therapy of pregnancy-induced hypertension].
    Gynakologische Rundschau, 1983, Volume: 23, Issue:3

    Topics: Anesthesia, Epidural; Epoprostenol; Female; Fenoterol; Humans; Hypertension; Labetalol; Metoprolol;

1983
Disposition of the adrenergic blocker metoprolol in the late-pregnant woman, the amniotic fluid, the cord blood and the neonate.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Amniotic Fluid; Drug Therapy, Combination; Female; Fetal Blood; Humans; Hydralazine; Hypertension; I

1984
Atenolol and metoprolol. A comparison of their excretion into human breast milk.
    Acta obstetricia et gynecologica Scandinavica. Supplement, 1984, Volume: 118

    Topics: Atenolol; Female; Fetal Blood; Humans; Hypertension; Metoprolol; Milk, Human; Pregnancy; Pregnancy C

1984
Disposition of metoprolol in the newborn.
    British journal of clinical pharmacology, 1981, Volume: 12, Issue:4

    Topics: Female; Humans; Hypertension; Infant, Newborn; Maternal-Fetal Exchange; Metoprolol; Pregnancy; Pregn

1981
[Myocardial infarction, pregnancy and anesthesia].
    Annales francaises d'anesthesie et de reanimation, 2000, Volume: 19, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; Analgesic

2000
Antihypertensive treatment with the adrenergic beta-receptor blocker metoprolol during pregnancy.
    Gynecologic investigation, 1978, Volume: 9, Issue:4

    Topics: Apgar Score; Drug Evaluation; Drug Therapy, Combination; Female; Fetal Growth Retardation; Fetus; Hu

1978
Successful resuscitation and survival following massive overdose of metoprolol.
    The British journal of clinical practice, 1990, Volume: 44, Issue:12

    Topics: Adult; Drug Overdose; Female; Glucagon; Heart Arrest; Humans; Metoprolol; Pregnancy; Pregnancy Compl

1990
Betaloc therapy in pregnancy-associated mild and moderately severe hypertension.
    Therapia Hungarica (English edition), 1990, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Blood Pressure; Female; Heart Rate; Heart Rate, Fetal; Humans; Hypertension; Infa

1990
Determination of light-chain myosin in pregnancy and under tocolysis.
    Journal of perinatal medicine, 1989, Volume: 17, Issue:6

    Topics: Coronary Disease; Female; Hexoprenaline; Humans; Immunoenzyme Techniques; Metoprolol; Myosins; Pregn

1989
The effect of hydralazine on steady-state plasma concentrations of metoprolol in pregnant hypertensive women.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:2

    Topics: Adult; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Meto

1988
Intravascular epinephrine may not increase heart rate in patients receiving metoprolol.
    Anesthesiology, 1988, Volume: 68, Issue:5

    Topics: Epinephrine; Female; Heart Rate; Humans; Metoprolol; Pregnancy; Pregnancy Complications, Cardiovascu

1988
Disposition of the adrenergic blocker metoprolol and its metabolite OH-metoprolol in maternal plasma, amniotic fluid and capillary blood of the neonate.
    European journal of clinical pharmacology, 1987, Volume: 33, Issue:4

    Topics: Amniotic Fluid; Capillaries; Female; Half-Life; Humans; Hypertension; Infant, Newborn; Male; Metopro

1987
Acute effects of dihydralazine mesylate, furosemide, and metoprolol on maternal hemodynamics in pregnancy-induced hypertension.
    American journal of obstetrics and gynecology, 1986, Volume: 155, Issue:1

    Topics: Adult; Blood Pressure; Blood Volume; Cardiac Output; Chorionic Villi; Dihydralazine; Female; Furosem

1986
Pregnancy-induced increase in metoprolol metabolism.
    Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:6

    Topics: Adult; Blood Proteins; Female; Humans; Hypertension; Kinetics; Metoprolol; Pregnancy; Pregnancy Comp

1985