metoprolol has been researched along with Cardiomyopathy, Hypertrophic in 33 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Cardiomyopathy, Hypertrophic: A form of CARDIAC MUSCLE disease, characterized by left and/or right ventricular hypertrophy (HYPERTROPHY, LEFT VENTRICULAR; HYPERTROPHY, RIGHT VENTRICULAR), frequent asymmetrical involvement of the HEART SEPTUM, and normal or reduced left ventricular volume. Risk factors include HYPERTENSION; AORTIC STENOSIS; and gene MUTATION; (FAMILIAL HYPERTROPHIC CARDIOMYOPATHY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "We identified that carvedilol, a β-blocker not commonly used in HCM, suppresses contractile function and arrhythmia by inhibiting RyR2 (ryanodine receptor type 2)." | 8.31 | Improved Cardiac Performance and Decreased Arrhythmia in Hypertrophic Cardiomyopathy With Non-β-Blocking R-Enantiomer Carvedilol. ( Ashley, EA; Bernstein, D; Huang, Y; Kawana, M; Kirillova, A; Lane, KV; Parikh, VN; Perez, MV; Pruitt, BL; Seo, K; Wang, Q; Wheeler, MT; Wu, JC; Yadav, S; Yamamoto, Y, 2023) |
| " In this presentation a case of bradycardia after co-administration of paroxetine and metoprolol is reported." | 7.69 | [Bradycardia after beginning therapy with metoprolol and paroxetine]. ( Häfele, M; Hauger, B; König, F; Löble, M; Wolfersdorf, M; Wössner, S, 1996) |
| "Transient Left Ventricular Apical Ballooning Syndrome (TLVABS) has been described to occur in response to number of stressful events, drug effects or drug withdrawal." | 5.35 | Transient left ventricular apical ballooning syndrome caused by abrupt metoprolol withdrawal. ( Boguszewski, A; Jefic, D; Koul, D; Martini, W, 2008) |
| "We identified that carvedilol, a β-blocker not commonly used in HCM, suppresses contractile function and arrhythmia by inhibiting RyR2 (ryanodine receptor type 2)." | 4.31 | Improved Cardiac Performance and Decreased Arrhythmia in Hypertrophic Cardiomyopathy With Non-β-Blocking R-Enantiomer Carvedilol. ( Ashley, EA; Bernstein, D; Huang, Y; Kawana, M; Kirillova, A; Lane, KV; Parikh, VN; Perez, MV; Pruitt, BL; Seo, K; Wang, Q; Wheeler, MT; Wu, JC; Yadav, S; Yamamoto, Y, 2023) |
| "The use of beta-blocking drugs for dilated cardiomyopathy (DCM), however, is currently investigational." | 3.76 | Treatment of cardiac myopathies with beta blockers. What do we know, where do we go from here? ( Anderson, JL, 1988) |
| " In this presentation a case of bradycardia after co-administration of paroxetine and metoprolol is reported." | 3.69 | [Bradycardia after beginning therapy with metoprolol and paroxetine]. ( Häfele, M; Hauger, B; König, F; Löble, M; Wolfersdorf, M; Wössner, S, 1996) |
| "Disopyramide as an antiarrhythmic can be prescribed to patients with atrial fibrillation and, owing to its negative inotropic effect, to patients with hypertrophic obstructive cardiomyopathy." | 3.69 | Heart conduction disturbances and cardiovascular collapse after disopyramide and low-dose metoprolol in a patient with hypertrophic obstructive cardiomyopathy. ( Horvat, M; Pernat, A; Pohar, B, 1997) |
| "We present a case treated with aprindine and metoprolol combined with a DDD type pacemaker for repetitive monomorphic ventricular tachycardia." | 3.68 | [A case of repetitive monomorphic ventricular tachycardia]. ( Komatsu, C; Kubouchi, Y; Kudou, S; Kurusu, O; Nomoto, J; Okamura, T; Sanada, T; Tanoiri, T; Tokuhisa, Y, 1992) |
| "Treatment with metoprolol was associated with more negative LS values of the apical segment (-2." | 3.30 | Metoprolol Improves Left Ventricular Longitudinal Strain at Rest and during Exercise in Obstructive Hypertrophic Cardiomyopathy. ( Andersen, MJ; Dybro, AM; Jensen, MK; Nielsen, RR; Pedersen, ALD; Poulsen, SH; Rasmussen, TB, 2023) |
| "Transient Left Ventricular Apical Ballooning Syndrome (TLVABS) has been described to occur in response to number of stressful events, drug effects or drug withdrawal." | 1.35 | Transient left ventricular apical ballooning syndrome caused by abrupt metoprolol withdrawal. ( Boguszewski, A; Jefic, D; Koul, D; Martini, W, 2008) |
| "Incessant monomorphic ventricular tachycardia (VT) with a right bundle branch block morphology and a northwest axis is a rare arrhythmic complication in a patient with hypertrophic cardiomyopathy and apical left ventricular aneurysm." | 1.30 | Radiofrequency catheter ablation of sustained monomorphic ventricular tachycardia in hypertrophic cardiomyopathy. ( Blommaert, D; de Muinck, EB; Rodriguez, LM; Smeets, JL; Timmermans, C; van Dantzig, JM; Wellens, HJ, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (21.21) | 18.7374 |
| 1990's | 7 (21.21) | 18.2507 |
| 2000's | 8 (24.24) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 5 (15.15) | 2.80 |
| Authors | Studies |
|---|---|
| Dybro, AM | 5 |
| Rasmussen, TB | 5 |
| Nielsen, RR | 5 |
| Andersen, MJ | 5 |
| Jensen, MK | 5 |
| Poulsen, SH | 5 |
| Ladefoged, BT | 1 |
| Pedersen, ALD | 3 |
| Seo, K | 1 |
| Yamamoto, Y | 1 |
| Kirillova, A | 1 |
| Kawana, M | 1 |
| Yadav, S | 1 |
| Huang, Y | 1 |
| Wang, Q | 1 |
| Lane, KV | 1 |
| Pruitt, BL | 1 |
| Perez, MV | 1 |
| Bernstein, D | 1 |
| Wu, JC | 1 |
| Wheeler, MT | 1 |
| Parikh, VN | 1 |
| Ashley, EA | 1 |
| Mahowald, MK | 1 |
| Fender, EA | 1 |
| Prasad, A | 1 |
| Nishimura, RA | 1 |
| Huang, W | 1 |
| Guan, L | 1 |
| Liu, L | 1 |
| Mu, Y | 1 |
| Pizoń, T | 1 |
| Rajzer, M | 1 |
| Wojciechowska, W | 1 |
| Jastrzebski, M | 1 |
| Olszanecka, A | 1 |
| Rojek, M | 1 |
| Jurczyszyn, A | 1 |
| Czarnecka, D | 1 |
| Smith, BB | 1 |
| Nickels, AS | 1 |
| Sviggum, HP | 1 |
| Meena, DS | 1 |
| Meena, CB | 1 |
| Parvez, J | 1 |
| Ahmed, S | 1 |
| Hafeez, S | 1 |
| Ali, N | 1 |
| Ahmed, T | 1 |
| Stellpflug, SJ | 1 |
| Fritzlar, SJ | 1 |
| Cole, JB | 1 |
| Engebretsen, KM | 1 |
| Holger, JS | 1 |
| Katarzynska-Szymanska, A | 1 |
| Ochotny, R | 1 |
| Oko-Sarnowska, Z | 1 |
| Wachowiak-Baszynska, H | 1 |
| Krauze, T | 1 |
| Piskorski, J | 1 |
| Gwizdala, A | 1 |
| Mitkowski, P | 1 |
| Guzik, P | 1 |
| Wang, H | 1 |
| Yuan, L | 1 |
| Boon, D | 1 |
| van Goudoever, J | 1 |
| Huijskes, R | 1 |
| Piek, JJ | 1 |
| van Montfrans, GA | 1 |
| Konishi, C | 1 |
| Shiraishi, J | 1 |
| Muraguchi, N | 1 |
| Ohtsuki, K | 1 |
| Inoue, M | 1 |
| Tatsumi, T | 1 |
| Azuma, A | 1 |
| Matsubara, H | 1 |
| Binder, WD | 1 |
| Fifer, MA | 1 |
| King, ME | 1 |
| Stone, JR | 1 |
| Frustaci, A | 1 |
| Verardo, R | 1 |
| Sale, P | 1 |
| Toscano, F | 1 |
| Critelli, G | 1 |
| Russo, MA | 1 |
| Chimenti, C | 1 |
| Jefic, D | 1 |
| Koul, D | 1 |
| Boguszewski, A | 1 |
| Martini, W | 1 |
| Schmitto, JD | 1 |
| Hein, S | 1 |
| Bräuer, A | 1 |
| Popov, AF | 1 |
| Quintel, M | 1 |
| Schöndube, FA | 1 |
| Moses, JW | 1 |
| Borer, JS | 1 |
| Alvares, RF | 1 |
| Goodwin, JF | 1 |
| Yukawa, T | 1 |
| Numao, T | 1 |
| Motojima, S | 1 |
| Fukuda, T | 1 |
| Ikemori, R | 1 |
| Makino, S | 1 |
| Shimizu, T | 1 |
| Hayashi, T | 1 |
| Okamoto, M | 1 |
| Miyazaki, H | 1 |
| Tsuzuki, M | 1 |
| Ino, T | 1 |
| Ezaki, K | 1 |
| Hirano, M | 1 |
| König, F | 1 |
| Häfele, M | 1 |
| Hauger, B | 1 |
| Löble, M | 1 |
| Wössner, S | 1 |
| Wolfersdorf, M | 1 |
| Rodriguez, LM | 1 |
| Smeets, JL | 1 |
| Timmermans, C | 1 |
| Blommaert, D | 1 |
| van Dantzig, JM | 1 |
| de Muinck, EB | 1 |
| Wellens, HJ | 1 |
| Pernat, A | 1 |
| Pohar, B | 1 |
| Horvat, M | 1 |
| Kurusu, O | 1 |
| Kudou, S | 1 |
| Nomoto, J | 1 |
| Tanoiri, T | 1 |
| Tokuhisa, Y | 1 |
| Kubouchi, Y | 1 |
| Sanada, T | 1 |
| Komatsu, C | 1 |
| Okamura, T | 1 |
| Magnusson, Y | 1 |
| Wallukat, G | 1 |
| Guillet, JG | 1 |
| Hjalmarson, A | 1 |
| Hoebeke, J | 1 |
| Stäblein, A | 1 |
| Huber, I | 1 |
| von Scheidt, W | 1 |
| Anderson, JL | 1 |
| Leor, J | 1 |
| Levartowsky, D | 1 |
| Sharon, C | 1 |
| Farfel, Z | 1 |
| Northridge, DB | 1 |
| McMurray, JM | 1 |
| Colledge, NR | 1 |
| Fraser, DM | 1 |
| Stafford, WJ | 1 |
| Trohman, RG | 1 |
| Bilsker, M | 1 |
| Zaman, L | 1 |
| Castellanos, A | 1 |
| Myerburg, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Metoprolol on Myocardial Function, Perfusion, Hemodynamics and Heart Failure Symptoms in Patients With Hypertrophic Obstructive Cardiomyopathy.[NCT03532802] | Phase 2 | 30 participants (Actual) | Interventional | 2018-05-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for metoprolol and Cardiomyopathy, Hypertrophic
| Article | Year |
|---|---|
Hypertrophic obstructive cardiomyopathy with multiple coronary arteries to right ventricular microfistulas: a case report and review of the literature.
Topics: Adult; Angina Pectoris; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Coronary Angiography; | 2017 |
Beta-adrenergic antagonists in the treatment of patients with heart disease.
Topics: Acebutolol; Adrenergic beta-Agonists; Alprenolol; Animals; Arrhythmias, Cardiac; Bronchial Spasm; Ca | 1981 |
Treatment of cardiac myopathies with beta blockers. What do we know, where do we go from here?
Topics: Adrenergic beta-Antagonists; Cardiomyopathies; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic | 1988 |
4 trials available for metoprolol and Cardiomyopathy, Hypertrophic
| Article | Year |
|---|---|
Randomized Trial of Metoprolol in Patients With Obstructive Hypertrophic Cardiomyopathy.
Topics: Adrenergic beta-1 Receptor Antagonists; Aged; Cardiomyopathy, Hypertrophic; Cross-Over Studies; Doub | 2021 |
Effects of Metoprolol on Exercise Hemodynamics in Patients With Obstructive Hypertrophic Cardiomyopathy.
Topics: Cardiomyopathy, Hypertrophic; Hemodynamics; Humans; Metoprolol; Mitral Valve Insufficiency; Stroke V | 2022 |
Metoprolol Improves Left Ventricular Longitudinal Strain at Rest and during Exercise in Obstructive Hypertrophic Cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Hypertrophic; Echocardiography; Heart Ventricles; Human | 2023 |
Metoprolol Improves Left Ventricular Longitudinal Strain at Rest and during Exercise in Obstructive Hypertrophic Cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Hypertrophic; Echocardiography; Heart Ventricles; Human | 2023 |
Metoprolol Improves Left Ventricular Longitudinal Strain at Rest and during Exercise in Obstructive Hypertrophic Cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Hypertrophic; Echocardiography; Heart Ventricles; Human | 2023 |
Metoprolol Improves Left Ventricular Longitudinal Strain at Rest and during Exercise in Obstructive Hypertrophic Cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Hypertrophic; Echocardiography; Heart Ventricles; Human | 2023 |
Treatment of cardiac myopathies with beta blockers. What do we know, where do we go from here?
Topics: Adrenergic beta-Antagonists; Cardiomyopathies; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic | 1988 |
27 other studies available for metoprolol and Cardiomyopathy, Hypertrophic
| Article | Year |
|---|---|
Improved Cardiac Performance and Decreased Arrhythmia in Hypertrophic Cardiomyopathy With Non-β-Blocking R-Enantiomer Carvedilol.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Cardiomyopathy, Hypertrophic; Carvedilol | 2023 |
Exertional Syncope in an Athlete: The Answer is in the History and Exam.
Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Athletes; Cardiomyopathy, Hypertrophic; Echocardio | 2020 |
Apical hypertrophic cardiomyopathy with apical endomyocardial fibrosis and calcification: Two case reports.
Topics: Angiotensin-Converting Enzyme Inhibitors; Aspirin; Calcinosis; Cardiomyopathy, Hypertrophic; Echocar | 2019 |
[Hypertrophic cardiomyopathy with midventricular obstruction of the left ventricle (MVO)--case report].
Topics: Aged; Amiodarone; Cardiomyopathy, Hypertrophic; Defibrillators, Implantable; Female; Heart Ventricle | 2015 |
A rare combination of undiagnosed hypertrophic cardiomyopathy revealed by intraoperative anaphylaxis resulting in acute left ventricular outflow obstruction and cardiac arrest.
Topics: Aged; Anaphylaxis; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Cardiomyopathy, Hypertrophic; Echo | 2016 |
Hypertrophic cardiomyopathy in a patient of Klinefelter syndrome--a rare association.
Topics: Adrenergic beta-Antagonists; Adult; Androgens; Cardiomyopathy, Hypertrophic; Humans; Karyotyping; Kl | 2009 |
Cardiotoxic overdose treated with intravenous fat emulsion and high-dose insulin in the setting of hypertrophic cardiomyopathy.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Amiodarone; Cardiomyopathy, Hypertrophic; Cardiotoxin | 2011 |
Shortening baroreflex delay in hypertrophic cardiomyopathy patients -- an unknown effect of β-blockers.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Adult; Aged; Baroreflex; Bisoprolol; Cardiomyopa | 2013 |
TCM treatment of hypertrophic cardiomyopaphy--a case report.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiomyopathy, Hypertrophic; Fema | 2002 |
Diagnostic value of simultaneous non-invasive continuous, ambulatory finger blood pressure and electrocardiogram monitoring in a patient with hypertrophic obstructive cardiomyopathy.
Topics: Anti-Arrhythmia Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cardiomyopathy, Hyper | 2002 |
Beneficial effect of cibenzoline on left ventricular pressure gradient with sigmoid septum.
Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Blood Pressure; Cardiomyopathy, Hypertrophic; Dyspn | 2004 |
Case records of the Massachusetts General Hospital. Case 26-2005. A 48-year-old man with sudden loss of consciousness while jogging.
Topics: Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Death, Sudden, Cardiac; Diagnosis, Differentia | 2005 |
Hypersensitivity myocarditis induced by beta-blockers: an unexpected cause of abrupt deterioration in hypertrophic cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Cardiomyopathy, Hypertrophic; Drug Hypersensitivity; Female; Hum | 2007 |
Transient left ventricular apical ballooning syndrome caused by abrupt metoprolol withdrawal.
Topics: Cardiomyopathy, Hypertrophic; Female; Humans; Metoprolol; Middle Aged; Substance Withdrawal Syndrome | 2008 |
Perioperative myocardial infarction after cesarean section in a young woman with hypertrophic obstructive cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Local; | 2008 |
Non-invasive assessment of diastolic function in hypertrophic cardiomyopathy on and off beta adrenergic blocking drugs.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Cardiomyopathy, Hypertrophic; Diastole; Female; Hear | 1982 |
[Effective combined therapy of selective beta 1-adrenergic antagonist and selective beta 2-adrenergic agonist in a patient with bronchial asthma and hypertrophic cardiomyopathy].
Topics: Albuterol; Asthma; Cardiomyopathy, Hypertrophic; Drug Therapy, Combination; Female; Humans; Metoprol | 1984 |
[Long-term selective beta 1-blockade therapy for a patient with anthracycline-induced cardiomyopathy].
Topics: Aclarubicin; Adrenergic beta-Antagonists; Adult; Antibiotics, Antineoplastic; Cardiomyopathy, Hypert | 1995 |
[Bradycardia after beginning therapy with metoprolol and paroxetine].
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Second-Generation; Blood Pressure; Bradycardia; | 1996 |
Radiofrequency catheter ablation of sustained monomorphic ventricular tachycardia in hypertrophic cardiomyopathy.
Topics: Aged; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Catheter Ablation; Electric Stimulation; | 1997 |
Heart conduction disturbances and cardiovascular collapse after disopyramide and low-dose metoprolol in a patient with hypertrophic obstructive cardiomyopathy.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiomyopathy, Hypertrophic; Dis | 1997 |
[A case of repetitive monomorphic ventricular tachycardia].
Topics: Aprindine; Cardiac Pacing, Artificial; Cardiomyopathy, Hypertrophic; Drug Therapy, Combination; Elec | 1992 |
Functional analysis of rabbit anti-peptide antibodies which mimic autoantibodies against the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy.
Topics: Amino Acid Sequence; Animals; Autoantibodies; Binding Sites; Binding, Competitive; Cardiomyopathy, H | 1991 |
[Life threatening syncope in a 69-year-old male: syndrome of hyperactive parasympathetic counter-regulation].
Topics: Aged; Cardiomyopathy, Hypertrophic; Cerebral Hemorrhage; Hemodynamics; Homeostasis; Humans; Isoprote | 1990 |
Amiodarone and beta-adrenergic blockers: an interaction with metoprolol but not with atenolol.
Topics: Amiodarone; Atenolol; Bradycardia; Cardiomyopathy, Hypertrophic; Drug Interactions; Drug Therapy, Co | 1988 |
Hypertensive hypertrophic cardiomyopathy of the elderly.
Topics: Aged; Cardiomyopathy, Hypertrophic; Diltiazem; Humans; Hypertension, Malignant; Male; Metoprolol | 1987 |
Cardiac arrest in an adolescent with atrial fibrillation and hypertrophic cardiomyopathy.
Topics: Adolescent; Atrial Fibrillation; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiomyopathy | 1986 |