metoprolol has been researched along with Cardiomyopathy, Congestive in 130 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study demonstrates that during long-term therapy, carvedilol improves cardiac performance to a greater extent than metoprolol when administered to patients with heart failure in the doses shown to be effective in clinical trials." | 9.09 | Differential effects of beta-blockers in patients with heart failure: A prospective, randomized, double-blind comparison of the long-term effects of metoprolol versus carvedilol. ( Boldi, E; Dei Cas, L; Giubbini, R; Metra, M; Modena, MG; Nodari, S, 2000) |
| " Metoprolol treatment restores the blunted inotropic response to milrinone in patients with heart failure, indicating that postreceptor events (e." | 9.08 | Improvement of postreceptor events by metoprolol treatment in patients with chronic heart failure. ( Böhm, M; Deutsch, HJ; Hartmann, D; Rosée, KL; Stäblein, A, 1997) |
| "Hemodynamic effects of the beta-receptor-blocking agent metoprolol (100 mg orally) and the calcium antagonist verapamil (160 mg orally) were analyzed in 24 patients with atrial fibrillation of different etiology (idiopathic atrial fibrillation, 6 cases; congestive cardiomyopathy, 6 cases; mitral stenosis, 5 cases; mitral regurgitation, 6 cases)." | 9.05 | [Modification of hemodynamics in tachycardiac atrial fibrillation by metoprolol and verapamil]. ( Bilgin, Y; Gigler, G; Maier, WD; Neuss, H; Schlepper, M; Thormann, J, 1983) |
| "To investigate the effects of beta-blocker (metoprolol) or angiotensin-converting enzyme inhibitor (captopril) treatment on neurohormonal function in a randomized prospective study on patients with heart failure due to dilated cardiomyopathy." | 7.70 | The circulating renin-angiotensin system during treatment with metoprolol or captopril in patients with heart failure due to non-ischaemic dilated cardiomyopathy. ( Dahlström, U; Jansson, K; Karlberg, BE; Karlberg, KE; Karlsson, E; Nylander, E; Nyquist, O, 1999) |
| " beta-receptor density and ejection fraction in congestive heart failure (CHF) before and after conventional therapy with small dose of beta-blocker (metoprolol) or captopril were compared." | 7.68 | [Changes in lymphocyte beta-receptor density in patients with heart failure before and after metoprolol or captopril administration]. ( Ma, C; Qin, S, 1992) |
| "To define the effects of 2 months of metoprolol therapy on cardiac function, aerobic performance and sympathetic nervous system activity, metoprolol (75 to 100 mg/day) was administered to 10 patients with chronic congestive heart failure (CHF)." | 7.68 | Effects of metoprolol on rest and exercise cardiac function and plasma catecholamines in chronic congestive heart failure secondary to ischemic or idiopathic cardiomyopathy. ( Abrass, IB; Nemanich, JW; Stratton, JR; Veith, RC, 1990) |
| " The study medication was titrated over 6 weeks, the mean final dosage was 135 mg/day." | 6.69 | MIC trial: metoprolol in patients with mild to moderate heart failure: effects on ventricular function and cardiopulmonary exercise testing. ( Böhm, M; Darius, H; Genth-Zotz, S; Hanrath, P; Hartmann, D; Meyer, J; Sigmund, M; Treese, N; Waagstein, F; Zotz, RJ, 2000) |
| "Thirty consecutive DCM patients with persistent LV dysfunction (ejection fraction < or =40%) and reduced exercise tolerance (peak oxygen consumption <25 ml/kg/min) despite chronic (>1 year) tailored treatment with metoprolol and angiotensin-converting enzyme inhibitors were enrolled in a 12-month, open-label, parallel trial and were randomized either to continue on metoprolol (n = 16, mean dosage 142+/-44 mg/day) or to cross over to maximum tolerated dosage of carvedilol (n = 14, mean dosage 74+/-23 mg/day)." | 6.69 | Long-term effects of carvedilol in idiopathic dilated cardiomyopathy with persistent left ventricular dysfunction despite chronic metoprolol. The Heart-Muscle Disease Study Group. ( Camerini, F; Ciani, F; Di Lenarda, A; Gregori, D; Klugmann, S; Mestroni, L; Muzzi, A; Pinamonti, B; Sabbadini, G; Salvatore, L; Sinagra, G, 1999) |
| "Metoprolol is a beta 1-selective adrenoceptor antagonist that is widely used in several indications." | 6.39 | Metoprolol: a pharmacoeconomic and quality-of-life evaluation of its use in hypertension, post-myocardial infarction and dilated cardiomyopathy. ( Benfield, P; Peters, DH, 1994) |
| "The purpose of the study was to evaluate the influence of metoprolol succinate and carvedilol on the physical ability (FA) of patients with chronic heart failure (CHF) of different etiologies." | 5.12 | [The effects of beta-adrenoblocker therapy on the physical working capacity of patients with chronic heart failure of various origin]. ( Andreev, DA; Kalashnikov, VIu; Poltavskaia, MG; Sarkisova, EA; Svet, AV; Syrkin, AL, 2007) |
| "The present study demonstrates that during long-term therapy, carvedilol improves cardiac performance to a greater extent than metoprolol when administered to patients with heart failure in the doses shown to be effective in clinical trials." | 5.09 | Differential effects of beta-blockers in patients with heart failure: A prospective, randomized, double-blind comparison of the long-term effects of metoprolol versus carvedilol. ( Boldi, E; Dei Cas, L; Giubbini, R; Metra, M; Modena, MG; Nodari, S, 2000) |
| " Metoprolol treatment restores the blunted inotropic response to milrinone in patients with heart failure, indicating that postreceptor events (e." | 5.08 | Improvement of postreceptor events by metoprolol treatment in patients with chronic heart failure. ( Böhm, M; Deutsch, HJ; Hartmann, D; Rosée, KL; Stäblein, A, 1997) |
| "Hemodynamic effects of the beta-receptor-blocking agent metoprolol (100 mg orally) and the calcium antagonist verapamil (160 mg orally) were analyzed in 24 patients with atrial fibrillation of different etiology (idiopathic atrial fibrillation, 6 cases; congestive cardiomyopathy, 6 cases; mitral stenosis, 5 cases; mitral regurgitation, 6 cases)." | 5.05 | [Modification of hemodynamics in tachycardiac atrial fibrillation by metoprolol and verapamil]. ( Bilgin, Y; Gigler, G; Maier, WD; Neuss, H; Schlepper, M; Thormann, J, 1983) |
| "The use of beta-blocking drugs for dilated cardiomyopathy (DCM), however, is currently investigational." | 3.76 | Treatment of cardiac myopathies with beta blockers. What do we know, where do we go from here? ( Anderson, JL, 1988) |
| " The aim of the present study was to investigate the prevalence of hypertension in patients with dilated cardiomyopathy (DCM) and to determine the tolerance and efficacy of a high dose of the β1-adrenoceptor antagonist metoprolol in the long-term treatment of DCM patients." | 3.75 | Dilated cardiomyopathy with hypertension: prevalence and response to high-dose β1-adrenoceptor antagonist therapy. ( Chen, S; Chen, Y; Wang, J; Yang, T; Zheng, X, 2009) |
| "Thus, a parallel improvement of myocardial NE reuptake and of hemodynamics was observed after a 6-mo metoprolol therapy, suggesting that such agents may be beneficial in heart failure by directly protecting the myocardium against excessive NE stimulation." | 3.70 | Sympathetic nerve alterations assessed with 123I-MIBG in the failing human heart. ( Castaigne, A; Delahaye, N; Dubois-Randé, JL; Fumey, R; Merlet, P; Pouillart, F; Syrota, A, 1999) |
| "To investigate the effects of beta-blocker (metoprolol) or angiotensin-converting enzyme inhibitor (captopril) treatment on neurohormonal function in a randomized prospective study on patients with heart failure due to dilated cardiomyopathy." | 3.70 | The circulating renin-angiotensin system during treatment with metoprolol or captopril in patients with heart failure due to non-ischaemic dilated cardiomyopathy. ( Dahlström, U; Jansson, K; Karlberg, BE; Karlberg, KE; Karlsson, E; Nylander, E; Nyquist, O, 1999) |
| "Metoprolol improves ventricular function in some children with dilated cardiomyopathy and congestive heart failure." | 3.70 | Beta-blocker treatment of dilated cardiomyopathy with congestive heart failure in children: a multi-institutional experience. ( Gidding, SS; Gilbert, EM; Lemes, V; Orsmond, GS; Pahl, E; Shaddy, RE; Tani, LY, 1999) |
| " beta-receptor density and ejection fraction in congestive heart failure (CHF) before and after conventional therapy with small dose of beta-blocker (metoprolol) or captopril were compared." | 3.68 | [Changes in lymphocyte beta-receptor density in patients with heart failure before and after metoprolol or captopril administration]. ( Ma, C; Qin, S, 1992) |
| "To define the effects of 2 months of metoprolol therapy on cardiac function, aerobic performance and sympathetic nervous system activity, metoprolol (75 to 100 mg/day) was administered to 10 patients with chronic congestive heart failure (CHF)." | 3.68 | Effects of metoprolol on rest and exercise cardiac function and plasma catecholamines in chronic congestive heart failure secondary to ischemic or idiopathic cardiomyopathy. ( Abrass, IB; Nemanich, JW; Stratton, JR; Veith, RC, 1990) |
| "To evaluate the short- and long-term effects of beta-adrenergic blockade (metoprolol) as well as the reaction to withdrawal and readministration of metoprolol in severe heart failure, 33 patients (25 men and eight women; mean age, 47." | 3.67 | Long-term beta-blockade in dilated cardiomyopathy. Effects of short- and long-term metoprolol treatment followed by withdrawal and readministration of metoprolol. ( Bergh, CH; Caidahl, K; Hjalmarson, A; Waagstein, F; Wallentin, I, 1989) |
| "We compared 15 patients with dilated cardiomyopathy (DCM) who were receiving carvedilol (group A) with 15 patients with DCM who were receiving metoprolol (group B)." | 2.71 | Efficacy of carvedilol treatment on cardiac function and cardiac sympathetic nerve activity in patients with dilated cardiomyopathy: comparison with metoprolol therapy. ( Adachi, H; Hoshizaki, H; Isobe, N; Naito, S; Oshima, S; Seki, R; Taniguchi, K; Toyama, T, 2003) |
| "Patients were divided into two groups: ischemic heart disease (IHD) and idiopathic dilated cardiomyopathy (DCM)." | 2.71 | Increased exercise ejection fraction and reversed remodeling after long-term treatment with metoprolol in congestive heart failure: a randomized, stratified, double-blind, placebo-controlled trial in mild to moderate heart failure due to ischemic or idiop ( Andersson, B; Böhm, M; Darius, M; Delius, W; Goss, F; Osterziel, KJ; Sigmund, M; Strömblad, O; Trenkwalder, SP; Waagstein, F; Wahlqvist, I, 2003) |
| "We randomly assigned 53 patients with idiopathic dilated cardiomyopathy to treatment with a beta-adrenergic-receptor blocking agent (metoprolol or carvedilol) or placebo." | 2.70 | Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents. ( Abraham, WT; Bristow, MR; Ferguson, D; Gilbert, EM; Larrabee, P; Lindenfeld, J; Lowes, BD; Minobe, WA; Quaife, RA; Robertson, AD; Tsvetkova, T; Wolfel, EE, 2002) |
| "The efficacy of treating dilated cardiomyopathy with metoprolol was compared with that of carvedilol." | 2.70 | Comparative left ventricular functional and neurohumoral effects of chronic treatment with carvedilol versus metoprolol in patients with dilated cardiomyopathy. ( Hanatani, A; Hirooka, K; Hori, M; Ishida, Y; Komamura, K; Miyatake, K; Nakatani, S; Yamagishi, M; Yasumura, Y, 2001) |
| "Both metoprolol and captopril were well tolerated and had favourable effects on LV performance." | 2.69 | The value of repeated echocardiographic evaluation in patients with idiopathic dilated cardiomyopathy during treatment with metoprolol or captopril. ( Dahlström, U; Jansson, K; Karlberg, KE; Karlsson, E; Nylander, E; Nyquist, O, 2000) |
| "Thirty consecutive DCM patients with persistent LV dysfunction (ejection fraction < or =40%) and reduced exercise tolerance (peak oxygen consumption <25 ml/kg/min) despite chronic (>1 year) tailored treatment with metoprolol and angiotensin-converting enzyme inhibitors were enrolled in a 12-month, open-label, parallel trial and were randomized either to continue on metoprolol (n = 16, mean dosage 142+/-44 mg/day) or to cross over to maximum tolerated dosage of carvedilol (n = 14, mean dosage 74+/-23 mg/day)." | 2.69 | Long-term effects of carvedilol in idiopathic dilated cardiomyopathy with persistent left ventricular dysfunction despite chronic metoprolol. The Heart-Muscle Disease Study Group. ( Camerini, F; Ciani, F; Di Lenarda, A; Gregori, D; Klugmann, S; Mestroni, L; Muzzi, A; Pinamonti, B; Sabbadini, G; Salvatore, L; Sinagra, G, 1999) |
| " The study medication was titrated over 6 weeks, the mean final dosage was 135 mg/day." | 2.69 | MIC trial: metoprolol in patients with mild to moderate heart failure: effects on ventricular function and cardiopulmonary exercise testing. ( Böhm, M; Darius, H; Genth-Zotz, S; Hanrath, P; Hartmann, D; Meyer, J; Sigmund, M; Treese, N; Waagstein, F; Zotz, RJ, 2000) |
| "Captopril treatment increased HRV expressed as total power and low-frequency power in the frequency domain." | 2.69 | The effects of metoprolol and captopril on heart rate variability in patients with idiopathic dilated cardiomyopathy. ( Dahlström, U; Hagerman, I; Jansson, K; Karlberg, KE; Nylander, E; Nyquist, O; Ostlund, R, 1999) |
| "Twenty-six men with dilated cardiomyopathy underwent serial echocardiography on days 0 and 1 and months 1 and 3 of either metoprolol (n = 16) or standard therapy (n = 10)." | 2.68 | Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade. ( Cigarroa, CG; Eichhorn, EJ; Grayburn, PA; Hall, SA; Marcoux, L; Risser, RC, 1995) |
| "7 years; range 14-66 years) with DCM, advanced functional (NYHA III-IV) and severe left ventricular dysfunction (LVEF < or = 25%) underwent a test dosage with metoprolol (5 mg b." | 2.68 | [Safety and tolerability of beta-blockers in severe cardiac decompensation from dilated cardiomyopathy]. ( Camerini, F; Di Lenarda, A; Lardieri, G; Perkan, A; Pinamonti, B; Rakar, S; Secoli, G; Sinagra, G; Zecchin, M, 1995) |
| "The Metoprolol in Dilated Cardiomyopathy (MDC) trial was conducted as a large, multicenter trial to establish the effects of metoprolol on mortality and need for heart transplantation in patients with symptomatic idiopathic cardiomyopathy." | 2.68 | Quality of life on treatment with metoprolol in dilated cardiomyopathy: results from the MDC trial. Metoprolol in Dilated Cardiomyopathy trial. ( Hjalmarsson, A; Swedberg, K; Waagstein, F; Wiklund, I, 1996) |
| "Metoprolol-treated patients responded favorably, as expressed by improved exercise cardiac index ([mean +/- SD] placebo 4." | 2.67 | Improved exercise hemodynamic status in dilated cardiomyopathy after beta-adrenergic blockade treatment. ( Andersson, B; Hamm, C; Hjalmarson, A; Persson, S; Sinagra, G; Waagstein, F; Wikström, G, 1994) |
| "383 subjects with heart failure from idiopathic dilated cardiomyopathy (ejection fraction < 0." | 2.67 | Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group. ( Bristow, MR; Camerini, F; Fowler, MB; Gilbert, EM; Goss, FG; Hjalmarson, A; Johnson, MR; Silver, MA; Swedberg, K; Waagstein, F, 1993) |
| " Four pts (6%) did not tolerate the first test dosage of metoprolol and twenty-two patients were excluded from analysis because of inadequate follow-up or because they were enrolled in an international trial." | 2.67 | [Beta blocking agents in the treatment of dilated cardiomyopathy: review of the literature and clinical experience with 67 patients]. ( Camerini, F; Di Lenarda, A; Lardieri, G; Mestroni, L; Miani, D; Perkan, A; Pinamonti, B; Sinagra, G, 1992) |
| "Metoprolol was therefore found to be useful for treatment of DCM." | 2.67 | Effects of long-term beta-blockade (metoprolol) therapy in patients with dilated cardiomyopathy. ( Fukuzaki, H; Kawai, H; Kurozumi, H; Nomura, H; Takarada, A; Takeuchi, Y; Tsumura, Y; Yokota, Y, 1991) |
| "Metoprolol-treated patients had an improvement in mean exercise capacity by 3 mets (p less than ." | 2.66 | Improvement in symptoms and exercise tolerance by metoprolol in patients with dilated cardiomyopathy: a double-blind, randomized, placebo-controlled trial. ( Engelmeier, RS; Gunnar, RM; O'Connell, JB; Rad, N; Scanlon, PJ; Walsh, R, 1985) |
| "symptomatic dilated cardiomyopathy were studied in order to evaluate the effect of long term sympathetic beta-blockade with metoprolol." | 2.66 | [Chronic treatment of dilated cardiomyopathy by beta blocking agents. Clinical and hemodynamic follow-up]. ( Compostella, L; Cucchini, F; de Domenico, R; Iavernaro, A; Papalia, D; Zeppellini, R, 1988) |
| "All patients clinically had idiopathic dilated cardiomyopathy; however, at coronary angiography, four had occult coronary disease." | 2.65 | Oral beta-adrenergic blockade with metoprolol in chronic severe dilated cardiomyopathy. ( Anderson, ST; Currie, PJ; Federman, J; Harper, RW; Kelly, MJ; Lim, YL; McKenzie, A; Pitt, A, 1984) |
| "Metoprolol is a beta 1-selective adrenoceptor antagonist that is widely used in several indications." | 2.39 | Metoprolol: a pharmacoeconomic and quality-of-life evaluation of its use in hypertension, post-myocardial infarction and dilated cardiomyopathy. ( Benfield, P; Peters, DH, 1994) |
| "Forty-two patients with idiopathic dilated cardiomyopathy treated with the therapy were studied." | 1.37 | Effect of left ventricular reverse remodeling on long-term prognosis after therapy with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and β blockers in patients with idiopathic dilated cardiomyopathy. ( Doi, YL; Furuno, T; Hoshikawa, E; Kitaoka, H; Kubo, T; Matsumura, Y; Okawa, M; Takata, J; Yamasaki, N, 2011) |
| "Fifty consecutive patients with dilated cardiomyopathy in NYHA class II-IV with a left ventricular ejection fraction (LVEF) of 35% or below were studied with full polysomnography over one night." | 1.34 | Does beta-blocker treatment influence central sleep apnoea? ( Köhnlein, T; Welte, T, 2007) |
| "Seven transgenic lines developed dilated cardiomyopathy and premature death from congestive heart failure." | 1.33 | Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase. ( Abel, ED; Bisping, E; Buerger, A; Dorfman, AL; Izumo, S; Jay, PY; Pu, WT; Rozhitskaya, O; Sherwood, MC, 2006) |
| "Metoprolol tartrate was added to the usual therapy, with a starting dose of 12." | 1.33 | Effects of metoprolol tartrate therapy in patients with heart failure. ( de Figueiredo Neto, JA; Grupi, C; Mady, C, 2006) |
| "In idiopathic dilated cardiomyopathy, the more significant improvement in symptoms and left ventricular function and size, that is observed following treatment using metoprolol, translates into a better outcome." | 1.31 | Metoprolol-induced functional benefit in dilated cardiomyopathy is sustained over four years and favorably influences outcome. ( De Maria, R; Di Lenarda, A; Gavazzi, A; Parolini, M; Porcu, M; Sinagra, G, 2001) |
| "Metoprolol was associated with a 30% reduction in all cause mortality (7% to 48%, p = 0." | 1.30 | Long-term survival effect of metoprolol in dilated cardiomyopathy. The SPIC (Italian Multicentre Cardiomyopathy Study) Group. ( Bernobich, E; Camerini, F; De Maria, R; Di Lenarda, A; Gavazzi, A; Gregori, D; Longaro, F; Parolini, M; Salvatore, L; Sinagra, G, 1998) |
| "31 patients with dilated cardiomyopathy and without bundle branch block were included in a retrospective study and 16 in a prospective study." | 1.30 | Prediction of the effectiveness of long-term beta blocker treatment for dilated cardiomyopathy by signal averaged electrocardiography. ( Fukunami, M; Hoki, N; Hori, M; Kim, J; Kumagai, K; Ogita, H; Sanada, S; Shimonagata, T; Yamada, T, 1998) |
| "A 58-year-old man with idiopathic dilated cardiomyopathy was treated with incremental administration of a beta-blocker (metoprolol) and an angiotensin converting enzyme inhibitor (enarapril)." | 1.30 | Recovery of iodine-123 metaiodobenzylguanidine uptake associated with left ventricular functional recovery in a patient with dilated cardiomyopathy. Endomyocardial histological findings before and after the improvement of uptake. ( Imai, M; Kusachi, S; Mima, T; Morishita, N; Ueda, T; Yamaji, H, 1997) |
| "Carvedilol is a high-affinity, slightly beta 1-selective competitive beta-blocking agent, with a KD for beta 1-receptors of approximately 4-5 nM and a selectivity of sixfold to 39-fold for beta 1-receptors rather than beta 2-receptors, depending on the method used to assess subtype potency." | 1.28 | Receptor pharmacology of carvedilol in the human heart. ( Bristow, MR; Handwerger, D; Klein, J; Larrabee, P; Minobe, W; Müller-Beckmann, B; Port, JD; Roden, R; Skerl, L, 1992) |
| "Metoprolol did not cause any significant changes compared with the control group." | 1.28 | Beta-blocker treatment of dilated cardiomyopathy. Beneficial effect of carteolol in mice. ( Kawai, C; Matsumori, A; Okada, I; Tominaga, M; Yamada, T, 1991) |
| "Twenty patients with dilated cardiomyopathy (11 males and 9 females) aged from 14 to 54 (37." | 1.28 | Oral metoprolol therapy in dilated cardiomyopathy: hemodynamic evidence for improved diastolic function accompanying amelioration of symptoms. ( Arora, R; Khalilullah, M; Nair, M; Sethi, KK, 1990) |
| "Metoprolol was therefore found to be useful for treatment of DCM." | 1.28 | Effects of long-term beta-blockade therapy in patients with dilated cardiomyopathy--serial clinical and echocardiographic observations. ( Fukuzaki, H; Kawai, H; Nomura, H; Yokota, Y, 1992) |
| "Chronic treatment of heart failure patients with beta-adrenoceptor antagonists leads to an up-regulation of cardiac beta-adrenoceptors, but in a subtype-selective fashion: beta 1-selective antagonists increase only cardiac beta 1-adrenoceptors, whereas non-selective antagonists increase both beta 1- and beta 2-adrenoceptors." | 1.28 | Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors. ( Borst, HG; Brodde, OE; Maier, W; Michel, MC; Zerkowski, HR, 1989) |
| "Metoprolol was administered during a 6-month period to 14 patients with dilated cardiomyopathy to examine its effects on these abnormalities." | 1.28 | Increased beta-receptor density and improved hemodynamic response to catecholamine stimulation during long-term metoprolol therapy in heart failure from dilated cardiomyopathy. ( Bristow, MR; Fowler, MB; Ginsburg, R; Heilbrunn, SM; Shah, P; Valantine, HA, 1989) |
| "The pharmacologic treatment of dilated cardiomyopathy encompasses measures such as temporary administration of amino acids and calories for those who may be undernourished and avoidance of drugs such as alcohol, nicotine, amphetamines and high doses of tricyclic antidepressants." | 1.27 | Pharmacologic treatment of dilated cardiomyopathy with special reference to the role of beta-blockers. ( Waagstein, F, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (9.23) | 18.7374 |
| 1990's | 63 (48.46) | 18.2507 |
| 2000's | 49 (37.69) | 29.6817 |
| 2010's | 6 (4.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Erolu, E | 1 |
| Akalın, F | 1 |
| Saylan Çevik, B | 1 |
| Yücelten, D | 1 |
| Faiella, W | 1 |
| Bessoudo, R | 1 |
| Kaya, MG | 1 |
| Sarli, B | 1 |
| Akpek, M | 1 |
| Kaya, EG | 1 |
| Yarlioglues, M | 1 |
| Topsakal, R | 1 |
| Lam, YY | 1 |
| Braun, M | 1 |
| Edelmann, F | 1 |
| Knapp, M | 1 |
| Schön, S | 1 |
| Schwencke, C | 1 |
| Simonis, G | 1 |
| Borst, M | 1 |
| Weinbrenner, C | 1 |
| Strasser, RH | 1 |
| Zheng, X | 1 |
| Chen, S | 1 |
| Wang, J | 2 |
| Yang, T | 1 |
| Chen, Y | 1 |
| Zhan, DY | 1 |
| Morimoto, S | 2 |
| Du, CK | 1 |
| Wang, YY | 1 |
| Lu, QW | 1 |
| Tanaka, A | 1 |
| Ide, T | 1 |
| Miwa, Y | 1 |
| Takahashi-Yanaga, F | 1 |
| Sasaguri, T | 1 |
| Aguilar-Torres, R | 1 |
| Hoshikawa, E | 1 |
| Matsumura, Y | 1 |
| Kubo, T | 1 |
| Okawa, M | 1 |
| Yamasaki, N | 1 |
| Kitaoka, H | 1 |
| Furuno, T | 1 |
| Takata, J | 1 |
| Doi, YL | 1 |
| Blaich, A | 1 |
| Pahlavan, S | 1 |
| Tian, Q | 1 |
| Oberhofer, M | 1 |
| Poomvanicha, M | 1 |
| Lenhardt, P | 1 |
| Domes, K | 1 |
| Wegener, JW | 1 |
| Moosmang, S | 1 |
| Ruppenthal, S | 1 |
| Scholz, A | 1 |
| Lipp, P | 1 |
| Hofmann, F | 1 |
| Du, Y | 1 |
| Yan, L | 1 |
| Zhan, W | 1 |
| Song, K | 1 |
| Han, X | 1 |
| Li, X | 1 |
| Cao, J | 1 |
| Liu, H | 1 |
| Kasama, S | 1 |
| Toyama, T | 3 |
| Hoshizaki, H | 3 |
| Oshima, S | 3 |
| Taniguchi, K | 3 |
| Suzuki, T | 2 |
| Kurabayashi, M | 1 |
| Goineau, S | 1 |
| Pape, D | 2 |
| Guillo, P | 1 |
| Ramée, MP | 1 |
| Bellissant, E | 2 |
| Hara, Y | 6 |
| Hamada, M | 5 |
| Ohtsuka, T | 6 |
| Ogimoto, A | 5 |
| Saeki, H | 3 |
| Suzuki, J | 2 |
| Matsunaka, T | 2 |
| Nakata, S | 2 |
| Shigematsu, Y | 6 |
| Abraham, WT | 3 |
| Gilbert, EM | 5 |
| Lowes, BD | 4 |
| Minobe, WA | 2 |
| Larrabee, P | 4 |
| Roden, RL | 1 |
| Dutcher, D | 1 |
| Sederberg, J | 1 |
| Lindenfeld, JA | 1 |
| Wolfel, EE | 2 |
| Shakar, SF | 1 |
| Ferguson, D | 3 |
| Volkman, K | 1 |
| Linseman, JV | 1 |
| Quaife, RA | 2 |
| Robertson, AD | 3 |
| Bristow, MR | 8 |
| Scharhag, J | 1 |
| Meyer, T | 1 |
| Görge, G | 1 |
| Kindermann, W | 1 |
| Metra, M | 2 |
| Nodari, S | 2 |
| Parrinello, G | 1 |
| Giubbini, R | 2 |
| Manca, C | 1 |
| Dei Cas, L | 2 |
| Higaki, J | 2 |
| Taniguchi, Y | 1 |
| Ueshima, K | 1 |
| Chiba, I | 1 |
| Segawa, I | 1 |
| Kobayashi, N | 1 |
| Saito, M | 1 |
| Hiramori, K | 1 |
| Seki, R | 1 |
| Isobe, N | 1 |
| Adachi, H | 1 |
| Naito, S | 1 |
| Waagstein, F | 11 |
| Strömblad, O | 1 |
| Andersson, B | 5 |
| Böhm, M | 3 |
| Darius, M | 1 |
| Delius, W | 1 |
| Goss, F | 2 |
| Osterziel, KJ | 2 |
| Sigmund, M | 2 |
| Trenkwalder, SP | 1 |
| Wahlqvist, I | 1 |
| Hanrath, P | 2 |
| Schneider, CA | 1 |
| Inoue, A | 1 |
| Yamashina, S | 1 |
| Yamazaki, J | 1 |
| Ahmet, I | 3 |
| Krawczyk, M | 2 |
| Heller, P | 1 |
| Moon, C | 1 |
| Lakatta, EG | 3 |
| Talan, MI | 3 |
| Prendergast, HM | 1 |
| Soorya, N | 1 |
| Erickson, T | 1 |
| Cinquegrana, G | 1 |
| D'Aniello, L | 1 |
| Landi, M | 1 |
| Spinelli, L | 1 |
| Grande, G | 1 |
| De Prisco, F | 1 |
| Petretta, M | 1 |
| Green, P | 1 |
| Anshelevich, M | 1 |
| Talreja, A | 1 |
| Burcham, JL | 1 |
| Ravi, SM | 1 |
| Shirani, J | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Study of (R, R') and (S,S': R,R')- Fenoterol: Initial Clinical Evaluation for Pharmacokinetics, Pharmacodynamics, and Safety[NCT01440335] | Phase 1 | 29 participants (Actual) | Interventional | 2011-07-10 | Completed | ||
| Reverse Remodeling is Associated With Hemodynamic Improvement and Stabilization in Outpatients With Heart Failure With Reduced Ejection Fraction Treated With Sacubitril/Valsartan: an Echocardiographic Study[NCT04397302] | 652 participants (Actual) | Observational [Patient Registry] | 2019-01-13 | Completed | |||
| A Multicenter, Placebo-Controlled, 8-Month Study of the Effect of Twice Daily Carvedilol in Children With Congestive Heart Failure Due to Systemic Ventricular Systolic Dysfunction[NCT00052026] | Phase 3 | 161 participants (Actual) | Interventional | 2000-05-31 | Completed | ||
| Collaborative Systematic Overview of Randomised Controlled Trials of Beta-Blockers in the Treatment of Heart Failure[NCT00832442] | 18,240 participants (Anticipated) | Observational | 2008-08-31 | Enrolling by invitation | |||
| Assessment of Metabolic Function and Perfusion Using Positron Emission Tomography: An Analysis of Patients With Congestive Cardiomyopathy Before and After Beta-Blockers[NCT00001402] | Phase 2 | 130 participants | Interventional | 1994-01-31 | Completed | ||
| Pulse Reduction On Beta-blocker and Ivabradine Therapy[NCT02973594] | Phase 4 | 28 participants (Actual) | Interventional | 2016-11-30 | Completed | ||
| Withdrawal of Beta- Blockers and ACE Inhibitors After Left Ventricular Systolic Function Recovery in Patient With Dilated Cardiomyopathy: A Randomized Control Trial.[NCT02770443] | 22 participants (Actual) | Interventional | 2016-02-19 | Terminated (stopped due to Study closed to recruitment early as endpoints were reached on several participants) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for metoprolol and Cardiomyopathy, Congestive
| Article | Year |
|---|---|
[Adrenergic betablockers and heart failure].
Topics: Adrenergic beta-Antagonists; Bisoprolol; Cardiomyopathy, Dilated; Heart Failure; Humans; Metoprolol; | 1995 |
Controlled trials with beta blockers in heart failure: metoprolol as the prototype.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Female; Hemodynamics; Humans; Male; Metoprolol | 1993 |
Metoprolol: a pharmacoeconomic and quality-of-life evaluation of its use in hypertension, post-myocardial infarction and dilated cardiomyopathy.
Topics: Cardiomyopathy, Dilated; Cost of Illness; Cost-Benefit Analysis; Economics, Pharmaceutical; Follow-U | 1994 |
What type of beta-blocker should be used to treat chronic heart failure?
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Humans; Metoprolol; Pr | 2000 |
[Adrenergic beta receptor blockaders in congestive heart failure: potential mechanisms of their action].
Topics: Cardiomyopathy, Dilated; Heart Ventricles; Humans; Metoprolol; Propranolol; Receptors, Adrenergic, b | 1988 |
Treatment of cardiac myopathies with beta blockers. What do we know, where do we go from here?
Topics: Adrenergic beta-Antagonists; Cardiomyopathies; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic | 1988 |
49 trials available for metoprolol and Cardiomyopathy, Congestive
| Article | Year |
|---|---|
Evaluation of beta-blockers on left ventricular dyssynchrony and reverse remodeling in idiopathic dilated cardiomyopathy: A randomized trial of carvedilol and metoprolol.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Biomarkers; Carbazoles; Cardiomyopathy, Dilate | 2014 |
The calcium channel blocker felodipine attenuates the positive hemodynamic effects of the beta-blocker metoprolol in severe dilated cardiomyopathy--a prospective, randomized, double-blind and placebo-controlled study with invasive hemodynamic assessment.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiomyopathy, Dilated; Double-Blind Method; | 2009 |
Use of thallium-201 myocardial scintigraphy for the prediction of the response to beta-blocker therapy in patients with dilated cardiomyopathy.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated | 2002 |
Coordinate changes in Myosin heavy chain isoform gene expression are selectively associated with alterations in dilated cardiomyopathy phenotype.
Topics: Antihypertensive Agents; Atrial Natriuretic Factor; Biopsy; Calcium-Transporting ATPases; Carbazoles | 2002 |
Effect of beta-blockers on insulin resistance in patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Echocardi | 2003 |
Efficacy of carvedilol treatment on cardiac function and cardiac sympathetic nerve activity in patients with dilated cardiomyopathy: comparison with metoprolol therapy.
Topics: 3-Iodobenzylguanidine; Adrenergic Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Car | 2003 |
Increased exercise ejection fraction and reversed remodeling after long-term treatment with metoprolol in congestive heart failure: a randomized, stratified, double-blind, placebo-controlled trial in mild to moderate heart failure due to ischemic or idiop
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Double-Blind Method; Exercise; Exercise Test; | 2003 |
Effects of different degrees of sympathetic antagonism on cytokine network in patients with ischemic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Echocardiography; Fema | 2005 |
[The effects of beta-adrenoblocker therapy on the physical working capacity of patients with chronic heart failure of various origin].
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; | 2007 |
Oral beta-adrenergic blockade with metoprolol in chronic severe dilated cardiomyopathy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiomyopathy, Dila | 1984 |
[Modification of hemodynamics in tachycardiac atrial fibrillation by metoprolol and verapamil].
Topics: Atrial Fibrillation; Cardiac Output; Cardiomyopathy, Dilated; Heart Rate; Hemodynamics; Humans; Meto | 1983 |
Beta-1-selectivity is not essential to achieve therapeutic efficacy with beta-blockade therapy for idiopathic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathy, Dilated; Confounding Factors, Epidemiologi | 1995 |
Influence of beta-blockade with metoprolol on symptoms and functional capacity of patients with idiopathic dilated cardiomyopathy.
Topics: Adult; Aged; Cardiomyopathy, Dilated; Chronic Disease; Exercise Test; Exercise Tolerance; Female; He | 1994 |
Predictors of systolic and diastolic improvement in patients with dilated cardiomyopathy treated with metoprolol.
Topics: Adult; Aged; Cardiomyopathy, Dilated; Diastole; Double-Blind Method; Heart; Hemodynamics; Humans; Ma | 1995 |
Time course of improvement in left ventricular function, mass and geometry in patients with congestive heart failure treated with beta-adrenergic blockade.
Topics: Analysis of Variance; Cardiomyopathy, Dilated; Cross-Over Studies; Double-Blind Method; Echocardiogr | 1995 |
Angiotensin-converting enzyme inhibitors and beta-blockers in long-term treatment of dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardiac Catheterization; Card | 1995 |
Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group.
Topics: Adolescent; Adult; Aged; Cardiomyopathy, Dilated; Exercise Test; Female; Follow-Up Studies; Heart Tr | 1993 |
Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group.
Topics: Adolescent; Adult; Aged; Cardiomyopathy, Dilated; Exercise Test; Female; Follow-Up Studies; Heart Tr | 1993 |
Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group.
Topics: Adolescent; Adult; Aged; Cardiomyopathy, Dilated; Exercise Test; Female; Follow-Up Studies; Heart Tr | 1993 |
Beneficial effects of metoprolol in idiopathic dilated cardiomyopathy. Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group.
Topics: Adolescent; Adult; Aged; Cardiomyopathy, Dilated; Exercise Test; Female; Follow-Up Studies; Heart Tr | 1993 |
Effect of metoprolol on myocardial function and energetics in patients with nonischemic dilated cardiomyopathy: a randomized, double-blind, placebo-controlled study.
Topics: Cardiac Catheterization; Cardiomyopathy, Dilated; Cross-Over Studies; Double-Blind Method; Energy Me | 1994 |
Predictors of pressure and stroke volume response to afterload reduction with nitroprusside in patients with congestive heart failure secondary to idiopathic dilated cardiomyopathy.
Topics: Blood Pressure; Cardiac Catheterization; Cardiomyopathy, Dilated; Heart Failure; Humans; Metoprolol; | 1994 |
Post-exercise Doppler-echocardiographic haemodynamics in idiopathic dilated cardiomyopathy after metoprolol infusion.
Topics: Blood Pressure; Cardiac Output; Cardiomyopathy, Dilated; Depression, Chemical; Double-Blind Method; | 1994 |
Improved exercise hemodynamic status in dilated cardiomyopathy after beta-adrenergic blockade treatment.
Topics: Analysis of Variance; Cardiomyopathy, Dilated; Double-Blind Method; Europe; Exercise; Female; Hemody | 1994 |
[Safety and tolerability of beta-blockers in severe cardiac decompensation from dilated cardiomyopathy].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathy, Dilated; Female; Heart Failure | 1995 |
Changes in early and late diastolic filling patterns induced by long-term adrenergic beta-blockade in patients with idiopathic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Cardiac Catheterization; Cardiomyopathy, Dilated; Diastole; Echocardiog | 1996 |
Quality of life on treatment with metoprolol in dilated cardiomyopathy: results from the MDC trial. Metoprolol in Dilated Cardiomyopathy trial.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Double-Blind Method; Female; Humans; Male; Met | 1996 |
Second- and third-generation beta-blocking drugs in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiac Output, Low; Cardiomyopathy, Dilated; | 1997 |
More favourable haemodynamic effects from metoprolol than from captopril in patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiac Out | 1997 |
Improvement of postreceptor events by metoprolol treatment in patients with chronic heart failure.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathy, Dilated; Cardiotonic Agents; Drug Synergis | 1997 |
Effect of race in the response to metoprolol in patients with congestive heart failure secondary to idiopathic dilated or ischemic cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathy, Dilated; Female; Heart Failure; Hemodynami | 1997 |
3-year follow-up of patients randomised in the metoprolol in dilated cardiomyopathy trial. The Metoprolol in Dilated Cardiomyopathy (MDC) Trial Study Group.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Dose-Response Relationship, Drug; Double-Blind | 1998 |
Early reduction in plasma norepinephrine during beta-blocking therapy with metoprolol in chronic heart failure.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Chronic Disease; Echocardiography; Exercise Te | 1998 |
Long-term effects of carvedilol in idiopathic dilated cardiomyopathy with persistent left ventricular dysfunction despite chronic metoprolol. The Heart-Muscle Disease Study Group.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Carbazoles; Cardiomyopathy, D | 1999 |
The effects of metoprolol and captopril on heart rate variability in patients with idiopathic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiomyopa | 1999 |
Benefit of long-term treatment with metoprolol in patients with dilated cadiomyopathy receiving enalapril: focus on the pattern of left ventricular diastolic filling.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Cardiomyopathy, Dilate | 1999 |
Effects of metoprolol CR in patients with ischemic and dilated cardiomyopathy : the randomized evaluation of strategies for left ventricular dysfunction pilot study.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Delayed-Action Preparations; Dopamine; Double- | 2000 |
MIC trial: metoprolol in patients with mild to moderate heart failure: effects on ventricular function and cardiopulmonary exercise testing.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiac Volume; Cardiomyopathy, Dilated; Double-Blind Meth | 2000 |
Differential effects of beta-blockers in patients with heart failure: A prospective, randomized, double-blind comparison of the long-term effects of metoprolol versus carvedilol.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Female | 2000 |
The value of repeated echocardiographic evaluation in patients with idiopathic dilated cardiomyopathy during treatment with metoprolol or captopril.
Topics: Adult; Captopril; Cardiomyopathy, Dilated; Double-Blind Method; Echocardiography, Doppler; Female; F | 2000 |
Early changes in longitudinal performance predict future improvement in global left ventricular function during long term beta adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Cardiomyopathy, Dilated; Diastole; D | 2000 |
Effect of metoprolol on rest and exercise left ventricular systolic and diastolic function in idiopathic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Diastole; Double-Blind Method; Exercise; Femal | 2001 |
Comparative left ventricular functional and neurohumoral effects of chronic treatment with carvedilol versus metoprolol in patients with dilated cardiomyopathy.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Adult; Atrial Natriuretic Factor; Carbazoles; Ca | 2001 |
Comparison of effects of carvedilol versus metoprolol on cytokine levels in patients with idiopathic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Cytokines; Female; Hum | 2002 |
Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Calcium-Transporting ATPases; Carbazoles; Cardiomyopathy, | 2002 |
[A new future for beta blockers: metoprolol reduces mortality and the need for heart transplantation in patients with dilated cardiomyopathy].
Topics: Cardiomyopathy, Dilated; Europe; Heart Transplantation; Humans; Metoprolol; North America | 1992 |
[Beta blocking agents in the treatment of dilated cardiomyopathy: review of the literature and clinical experience with 67 patients].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathy, Dilated; Child; Female; Follow | 1992 |
Effects of long-term beta-blockade (metoprolol) therapy in patients with dilated cardiomyopathy.
Topics: Arrhythmias, Cardiac; Blood Pressure; Cardiomyopathy, Dilated; Echocardiography; Female; Follow-Up S | 1991 |
Treatment of cardiac myopathies with beta blockers. What do we know, where do we go from here?
Topics: Adrenergic beta-Antagonists; Cardiomyopathies; Cardiomyopathy, Dilated; Cardiomyopathy, Hypertrophic | 1988 |
[Chronic treatment of dilated cardiomyopathy by beta blocking agents. Clinical and hemodynamic follow-up].
Topics: Adrenergic beta-Antagonists; Cardiac Catheterization; Cardiomyopathy, Dilated; Clinical Trials as To | 1988 |
[Beta-blockade therapy in heart failure. Rational bases of the interpretation of clinical data and clinical evidence in search of rational interpretation].
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Clinical Trials as Topic; Heart Failure; Human | 1988 |
Improvement in symptoms and exercise tolerance by metoprolol in patients with dilated cardiomyopathy: a double-blind, randomized, placebo-controlled trial.
Topics: Adult; Bradycardia; Cardiomyopathy, Dilated; Clinical Trials as Topic; Exercise Test; Female; Heart | 1985 |
76 other studies available for metoprolol and Cardiomyopathy, Congestive
| Article | Year |
|---|---|
Arrhythmogenic right ventricular dysplasia, cutaneous manifestations and desmoplakin mutation: Carvajal syndrome.
Topics: Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Arrhythmogenic Rig | 2018 |
Cardiac manifestations in Emery-Dreifuss muscular dystrophy.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Defibrillators, Implantable; Ele | 2018 |
Dilated cardiomyopathy with hypertension: prevalence and response to high-dose β1-adrenoceptor antagonist therapy.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Analysis of Variance; Antihypertensive Agents; Blood | 2009 |
Therapeutic effect of {beta}-adrenoceptor blockers using a mouse model of dilated cardiomyopathy with a troponin mutation.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Dis | 2009 |
Found in translation: metoprolol improves survival more than carvedilol in a mouse model of inherited dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Animals; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Disease Model | 2009 |
Effect of left ventricular reverse remodeling on long-term prognosis after therapy with angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers and β blockers in patients with idiopathic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Conve | 2011 |
Mutation of the calmodulin binding motif IQ of the L-type Ca(v)1.2 Ca2+ channel to EQ induces dilated cardiomyopathy and death.
Topics: Amino Acid Motifs; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Bindin | 2012 |
β1-Adrenoceptor autoantibodies from DCM patients enhance the proliferation of T lymphocytes through the β1-AR/cAMP/PKA and p38 MAPK pathways.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Aged; Animals; Autoantibodies; Car | 2012 |
Dobutamine gated blood pool scintigraphy predicts the improvement of cardiac sympathetic nerve activity, cardiac function, and symptoms after treatment in patients with dilated cardiomyopathy.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardio | 2002 |
Combined effects of metoprolol and spironolactone in dilated cardiomyopathic hamsters.
Topics: Animals; Cardiomyopathy, Dilated; Cricetinae; Drug Therapy, Combination; Hemodynamics; Male; Metopro | 2002 |
Comparison of treatment effects of bevantolol and metoprolol on cardiac function and natriuretic peptides in patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Car | 2002 |
[Competitive sports and dilated cardiomyopathy: the case of a 32-year-old soccer player with ventricular tachycardia].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents | 2003 |
Marked improvement in left ventricular ejection fraction during long-term beta-blockade in patients with chronic heart failure: clinical correlates and prognostic significance.
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Female; Follow-Up Stud | 2003 |
A new method using pulmonary gas-exchange kinetics to evaluate efficacy of beta-blocking agents in patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Blood Pressure; Cardiomyopathy, Dilated; Carteol | 2003 |
[Is "COMET" pointing in the right direction?--Pro].
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Dose-Response Relation | 2003 |
[Is "COMET" pointing in the right direction?--Con].
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Dose-Response Relation | 2003 |
The effect of beta-blocker on hamster model BIO 53.58 with dilated cardiomyopathy determined using 123I-MIBG myocardial scintigraphy.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Animals; Carbazoles; Cardiomyopathy, Dilated; Ca | 2003 |
Beneficial effects of chronic pharmacological manipulation of beta-adrenoreceptor subtype signaling in rodent dilated ischemic cardiomyopathy.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonist | 2004 |
Sudden death after IV metoprolol administration in a patient with cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Alcoholism; Cardiomyopathy, Dilated; Death, Sudden, Cardiac; Ele | 2004 |
Long-term effects of carvedilol or metoprolol on left ventricular function in ischemic and nonischemic cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbazoles; Cardiomyopathy, Dilated; Ca | 2005 |
Effect of beta-blocker therapy on myocardial perfusion defects in thallium-201 scintigraphy in patients with dilated cardiomyopathy.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilo | 2005 |
Pharmacological stimulation of beta2-adrenergic receptors (beta2AR) enhances therapeutic effectiveness of beta1AR blockade in rodent dilated ischemic cardiomyopathy.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 2005 |
The effects of combined versus selective adrenergic blockade on left ventricular and systemic hemodynamics, myocardial substrate preference, and regional perfusion in conscious dogs with dilated cardiomyopathy.
Topics: Adrenergic Antagonists; Adrenergic beta-Agonists; Animals; Carbazoles; Cardiomyopathy, Dilated; Carv | 2006 |
Dilated cardiomyopathy resulting from high-level myocardial expression of Cre-recombinase.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Biomarker | 2006 |
Effects of metoprolol tartrate therapy in patients with heart failure.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Cardiac Output, Low; Cardiomyopathy, Dilated; | 2006 |
Direct effects of 3 combinations of enalapril, metoprolol, and spironolactone on cardiac remodeling in dilated cardiomyopathic hamsters.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiomyopathy, Dila | 2006 |
Does beta-blocker treatment influence central sleep apnoea?
Topics: Adrenergic beta-Antagonists; Carbazoles; Cardiac Output, Low; Cardiomyopathy, Dilated; Carvedilol; C | 2007 |
Cardioprotective and survival benefits of long-term combined therapy with beta2 adrenoreceptor (AR) agonist and beta1 AR blocker in dilated cardiomyopathy postmyocardial infarction.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonist | 2008 |
Possible adrenergic effects on heart protein metabolism.
Topics: Adrenergic beta-Antagonists; Amino Acids; Animals; Biological Transport; Cardiomegaly; Cardiomyopath | 1983 |
Reductions in muscle sympathetic nerve activity after long-term metoprolol for dilated cardiomyopathy: preliminary observations.
Topics: Adrenergic beta-Antagonists; Adult; Atrial Natriuretic Factor; Blood Pressure; Cardiomyopathy, Dilat | 1995 |
[Serial assessment of MIBG scintigraphy in a case of DCM with heart failure improved by beta-blocker therapy].
Topics: 3-Iodobenzylguanidine; Cardiomyopathy, Dilated; Follow-Up Studies; Heart; Heart Failure; Humans; Iod | 1995 |
[Beta-receptor blockers in dilated cardiomyopathy].
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathy, Dilated; Clinical Trials as To | 1994 |
Which subgroup of patients with dilated cardiomyopathy would benefit from long-term beta-blocker therapy? A histologic viewpoint.
Topics: Adrenergic beta-Antagonists; Biopsy; Cardiac Catheterization; Cardiomyopathy, Dilated; Echocardiogra | 1993 |
Reversion of tachycardiomyopathy after beta-blocker.
Topics: Adult; Atrial Fibrillation; Cardiomyopathy, Dilated; Exercise Test; Heart Failure; Heart Rate; Human | 1993 |
Effect of metoprolol on the beta-adrenoceptor density of lymphocytes in patients with dilated cardiomyopathy.
Topics: Adult; Aged; Cardiomyopathy, Dilated; Case-Control Studies; Echocardiography; Epinephrine; Humans; L | 1993 |
Beta-blocker treatment of idiopathic and ischemic dilated cardiomyopathy in patients with ejection fractions < or = 20%.
Topics: Aged; Cardiomyopathy, Dilated; Female; Humans; Male; Metoprolol; Middle Aged; Propranolol; Stroke Vo | 1993 |
A sustained increase in beta-adrenoceptors during long-term therapy with metoprolol and bisoprolol in patients with heart failure from idiopathic dilated cardiomyopathy.
Topics: Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Bisoprolol; Cardio | 1996 |
Metoprolol in dilated cardiomyopathy: is it possible to identify factors predictive of improvement? The Heart Muscle Disease Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Cardiomyopathy, Dilated; Echocardiography; Electrocardiography; | 1996 |
Use of iodine-123 metaiodobenzylguanidine myocardial imaging to predict the effectiveness of beta-blocker therapy in patients with dilated cardiomyopathy.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Adult; Cardiomyopathy, Dilated; Contrast Media; | 1997 |
Recovery of iodine-123 metaiodobenzylguanidine uptake associated with left ventricular functional recovery in a patient with dilated cardiomyopathy. Endomyocardial histological findings before and after the improvement of uptake.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biopsy | 1997 |
[Case of dilated cardiomyopathy with marked improvement of the cardiac function with beta block treatment and exacerbation with the interruption of the treatment].
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Heart; Humans; Male; Metoprolol; Middle Aged; | 1997 |
Abnormality in plasma catecholamines and myocardial adrenoceptors in cardiomyopathic BIO 53.58 Syrian hamsters and improvement by metoprolol treatment.
Topics: Adrenergic beta-Antagonists; Animals; Cardiomyopathy, Dilated; Catecholamines; Cricetinae; Male; Mes | 1997 |
Predictive value of heart rate in dilated cardiomyopathy treated with metoprolol.
Topics: Adrenergic beta-Antagonists; Adult; Analysis of Variance; Cardiomyopathy, Dilated; Exercise Test; Fe | 1997 |
Prediction of the effectiveness of long-term beta blocker treatment for dilated cardiomyopathy by signal averaged electrocardiography.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Electrocardiography; Female; Forecasting; Huma | 1998 |
Long-term survival effect of metoprolol in dilated cardiomyopathy. The SPIC (Italian Multicentre Cardiomyopathy Study) Group.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Cardiomyopathy, Dilate | 1998 |
When an AED meets an ICD... Automated external defibrillator. Implantable cardioverter defibrillator.
Topics: Adult; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Cardiopulmonary Resuscitation; Clinical Prot | 1998 |
Clinical usefulness of 123I meta-iodobenzylguanidine imaging in predicting the effectiveness of beta blockers for patients with idiopathic dilated cardiomyopathy before and soon after treatment.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Adult; Aged; Biomarkers; Cardiomyopathy, Dilated | 1999 |
Cardiac sympathetic activity estimated by 123I-MIBG myocardial imaging in patients with dilated cardiomyopathy after beta-blocker or angiotensin-converting enzyme inhibitor therapy.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhib | 1999 |
Sympathetic nerve alterations assessed with 123I-MIBG in the failing human heart.
Topics: 3-Iodobenzylguanidine; Adrenergic beta-Antagonists; Adult; Cardiomyopathy, Dilated; Echocardiography | 1999 |
Beta-blocker treatment of dilated cardiomyopathy with congestive heart failure in children: a multi-institutional experience.
Topics: Adolescent; Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Child; Child, Preschool; Echocardi | 1999 |
The circulating renin-angiotensin system during treatment with metoprolol or captopril in patients with heart failure due to non-ischaemic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriu | 1999 |
Effects of beta-adrenergic blocking therapy on left ventricular diastolic relaxation properties in patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Diastole; Female; Heart Rate; Humans; Male; Me | 1999 |
Effect of selective versus nonselective beta blockade on QT dispersion in patients with nonischemic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbazoles; Cardiomyopathy, Dilated; Carvedilol; Death, Su | 1999 |
[New milestones in the therapy of chronic heart failure with beta blockers].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bisoprolol; Carbazoles; Cardi | 2000 |
Myocardial scintigraphy using iodine-123 15-(p-iodophenyl)-3-R, S-methylpentadecanoic acid predicts the response to beta-blocker therapy in patients with dilated cardiomyopathy but does not reflect therapeutic effect.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathy, Dilated; Echocardiography; Fatty Acids; Fe | 2000 |
Beta-blockade in adriamycin-induced cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antineoplastic Agents; Carbazoles; Cardiomyopathies; Cardi | 2000 |
Effect of beta-blockers on circulating levels of inflammatory and anti-inflammatory cytokines in patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Bisoprolol; Cardiomyopathy, Dilated; Cytokines; Drug Thera | 2001 |
Metoprolol-induced functional benefit in dilated cardiomyopathy is sustained over four years and favorably influences outcome.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Female; Humans; Logistic Models; Male; Metopro | 2001 |
Anti beta1-adrenoceptor autoantibodies analyzed in spontaneously beating neonatal rat heart myocyte cultures-comparison of methods.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Autoantibodies; Bi | 2001 |
Relationship between evaluation by quantitative fatty acid myocardial scintigraphy and response to beta-blockade therapy in patients with dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Fatty Acids; Female; Heart; Humans; Iodine Rad | 2001 |
Catecholamine stimulation is associated with impaired myocardial O(2) utilization in heart failure.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Analysis of Varian | 2002 |
[Administration of metoprolol in refractory and severe heart failure].
Topics: Adult; Aged; Cardiomyopathy, Dilated; Female; Heart Failure; Heart Rate; Humans; Male; Metoprolol; M | 1992 |
[Changes in lymphocyte beta-receptor density in patients with heart failure before and after metoprolol or captopril administration].
Topics: Adult; Aged; Captopril; Cardiomyopathy, Dilated; Female; Heart Failure; Humans; Lymphocytes; Male; M | 1992 |
Receptor pharmacology of carvedilol in the human heart.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Binding, Competitive; Carbazoles; Cardiomyopat | 1992 |
Effects of long-term beta-blockade therapy in patients with dilated cardiomyopathy--serial clinical and echocardiographic observations.
Topics: Adult; Aged; Cardiomyopathy, Dilated; Drug Evaluation; Echocardiography; Exercise Test; Female; Foll | 1992 |
Beta-blocker treatment of dilated cardiomyopathy. Beneficial effect of carteolol in mice.
Topics: Adrenergic beta-Antagonists; Animals; Body Weight; Cardiomyopathy, Dilated; Carteolol; Drug Evaluati | 1991 |
Effectiveness of long-term beta-blocker therapy for dilated cardiomyopathy--echocardiographical follow-up.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cardiomyopathy, Dilated; Echocardiography; Endomyocardial | 1991 |
Exercise hemodynamics and myocardial metabolism during long-term beta-adrenergic blockade in severe heart failure.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Energy Metabolism; Epinephrine; Exercise; Fema | 1991 |
Beta-adrenergic blockade in congestive heart failure: answering the old questions.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Heart; Heart Failure; Hemodynamics; Humans; Me | 1991 |
Effects of metoprolol on rest and exercise cardiac function and plasma catecholamines in chronic congestive heart failure secondary to ischemic or idiopathic cardiomyopathy.
Topics: Aged; Cardiomyopathy, Dilated; Catecholamines; Chronic Disease; Coronary Disease; Epinephrine; Exerc | 1990 |
Oral metoprolol therapy in dilated cardiomyopathy: hemodynamic evidence for improved diastolic function accompanying amelioration of symptoms.
Topics: Adolescent; Adult; Blood Pressure; Cardiomyopathy, Dilated; Diastole; Female; Heart; Hemodynamics; H | 1990 |
Metoprolol in patients with dilated cardiomyopathy.
Topics: Cardiomyopathy, Dilated; Humans; Metoprolol; Survival Rate | 1990 |
Increased beta-receptor density and improved hemodynamic response to catecholamine stimulation during long-term metoprolol therapy in heart failure from dilated cardiomyopathy.
Topics: Cardiomyopathy, Dilated; Dobutamine; Hemodynamics; Humans; Metoprolol; Middle Aged; Myocardial Contr | 1989 |
Long-term beta-blockade in dilated cardiomyopathy. Effects of short- and long-term metoprolol treatment followed by withdrawal and readministration of metoprolol.
Topics: Adolescent; Adult; Aged; Cardiac Catheterization; Cardiomyopathy, Dilated; Drug Evaluation; Echocard | 1989 |
Drug- and disease-induced changes of human cardiac beta 1- and beta 2-adrenoceptors.
Topics: Adolescent; Adult; Cardiomyopathy, Dilated; Child; Child, Preschool; Coronary Disease; Heart Failure | 1989 |
Pharmacologic treatment of dilated cardiomyopathy with special reference to the role of beta-blockers.
Topics: Adrenergic beta-Antagonists; Cardiomyopathy, Dilated; Drug Therapy, Combination; Electrocardiography | 1985 |