Page last updated: 2024-10-31

metoprolol and Bradyarrhythmia

metoprolol has been researched along with Bradyarrhythmia in 62 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Research Excerpts

ExcerptRelevanceReference
"To investigate the influence of paroxetine on metoprolol concentrations and its effect in patients treated for acute myocardial infarction (AMI) who are routinely given paroxetine as a co-treatment of depression."9.13Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI). ( Babak, S; Bergman, U; Bertilsson, L; Boldueva, S; Burbello, A; Goryachkina, K, 2008)
"To report a sinus bradycardia induced by metoprolol and terbinafine drug-drug interaction and its management."7.81A metoprolol-terbinafine combination induced bradycardia. ( Bebawi, E; Brindamour, D; Doré, M; Frenette, AJ; Jouni, SS; Tessier, AA, 2015)
"To estimate and compare the risk of emergent bradycardia associated with starting immediate-release (IR) and slow-release (SR) formulations of metoprolol."7.79Risk of emergent bradycardia associated with initiation of immediate- or slow-release metoprolol. ( Gonzales, M; Pletcher, MJ; Shin, J, 2013)
"Large randomized trials have reported mixed results regarding the risk of bradycardia between metoprolol and carvedilol."7.79Risk of emergent bradycardia associated with the use of carvedilol and metoprolol in routine clinical practice. ( Pletcher, MJ; Shin, J, 2013)
"5 mg of alprazolam daily for 1 year and with 50 mg of metoprolol daily for 15 days, presented to a facility elsewhere with presyncope and complete atrioventricular block."7.74Complete atrioventricular block associated with concomitant use of metoprolol and paroxetine. ( Bekar, L; Cumurcu, BE; Onalan, O, 2008)
" We report a case of this inhibition manifested by life-threatening bradycardia in a patient receiving a CYP2D6 substrate, metoprolol."7.73Profound metoprolol-induced bradycardia precipitated by acetaminophen-propoxyphene. ( Lang, L; Lehmann, DF; Marraffa, JM; Ong, G, 2006)
"Bupropion is an increasingly prescribed agent to aid in smoking cessation."7.72Severe sinus bradycardia after initiation of bupropion therapy: a probable drug-drug interaction with metoprolol. ( Greene, JL; McCollum, DL; McGuire, DK, 2004)
" In this presentation a case of bradycardia after co-administration of paroxetine and metoprolol is reported."7.69[Bradycardia after beginning therapy with metoprolol and paroxetine]. ( Häfele, M; Hauger, B; König, F; Löble, M; Wolfersdorf, M; Wössner, S, 1996)
"Ivabradine is a selective bradycardic agent that inhibits hyperpolarization-activated cyclic nucleotide-gated (HCN) channels."5.51Ivabradine preserves dynamic sympathetic control of heart rate despite inducing significant bradycardia in rats. ( Hayama, Y; Kawada, T; Nishikawa, T; Shimizu, S; Shishido, T; Sugimachi, M; Uemura, K; Yamamoto, H, 2019)
"To investigate the influence of paroxetine on metoprolol concentrations and its effect in patients treated for acute myocardial infarction (AMI) who are routinely given paroxetine as a co-treatment of depression."5.13Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI). ( Babak, S; Bergman, U; Bertilsson, L; Boldueva, S; Burbello, A; Goryachkina, K, 2008)
"A clinically significant interaction between epinephrine or levonordefrin with nonselective beta-adrenergic blocking agents, although apparently rare in the dental setting, is potentially serious and can lead to significant hypertension with a concomitant reflex bradycardia."4.86Beta-adrenergic blocking agents and dental vasoconstrictors. ( Giannakopoulos, H; Hersh, EV, 2010)
"Our findings suggest that neonates born to mothers exposed to β blockers in late pregnancy, including labetalol, are at elevated risk for neonatal hypoglycemia and bradycardia."3.83Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia. ( Bateman, BT; Desai, RJ; Fischer, MA; Hernandez-Diaz, S; Huybrechts, KF; Maeda, A; Mogun, H; Patorno, E; Seely, EW, 2016)
"To report a sinus bradycardia induced by metoprolol and terbinafine drug-drug interaction and its management."3.81A metoprolol-terbinafine combination induced bradycardia. ( Bebawi, E; Brindamour, D; Doré, M; Frenette, AJ; Jouni, SS; Tessier, AA, 2015)
"To estimate and compare the risk of emergent bradycardia associated with starting immediate-release (IR) and slow-release (SR) formulations of metoprolol."3.79Risk of emergent bradycardia associated with initiation of immediate- or slow-release metoprolol. ( Gonzales, M; Pletcher, MJ; Shin, J, 2013)
"Large randomized trials have reported mixed results regarding the risk of bradycardia between metoprolol and carvedilol."3.79Risk of emergent bradycardia associated with the use of carvedilol and metoprolol in routine clinical practice. ( Pletcher, MJ; Shin, J, 2013)
"5 mg of alprazolam daily for 1 year and with 50 mg of metoprolol daily for 15 days, presented to a facility elsewhere with presyncope and complete atrioventricular block."3.74Complete atrioventricular block associated with concomitant use of metoprolol and paroxetine. ( Bekar, L; Cumurcu, BE; Onalan, O, 2008)
" We report a case of this inhibition manifested by life-threatening bradycardia in a patient receiving a CYP2D6 substrate, metoprolol."3.73Profound metoprolol-induced bradycardia precipitated by acetaminophen-propoxyphene. ( Lang, L; Lehmann, DF; Marraffa, JM; Ong, G, 2006)
"The present study addressed possible alterations in the pharmacodynamic and pharmacokinetic properties of the beta1-adrenoceptor antagonist metoprolol in experimental hypertension induced by abdominal aortic coarctation (ACo)."3.72Pharmacokinetic-pharmacodynamic properties of metoprolol in chronic aortic coarctated rats. ( Di Verniero, C; Höcht, C; Opezzo, JA; Taira, CA, 2004)
"Bupropion is an increasingly prescribed agent to aid in smoking cessation."3.72Severe sinus bradycardia after initiation of bupropion therapy: a probable drug-drug interaction with metoprolol. ( Greene, JL; McCollum, DL; McGuire, DK, 2004)
" In the present study, we investigated the effect of a single bolus administration of L-NAME on blood pressure and heart rate monitored for one hour in anesthetized rats and the influence of vagotomy and beta1-receptor blocker metoprolol on the L-NAME induced bradycardia."3.71Inhibition of beta-1 receptor but not vagotomy can abolish the L-NAME evoked bradycardia in anesthetized rat. ( Bartha, J; Hably, C; Vág, J, 2002)
" In this presentation a case of bradycardia after co-administration of paroxetine and metoprolol is reported."3.69[Bradycardia after beginning therapy with metoprolol and paroxetine]. ( Häfele, M; Hauger, B; König, F; Löble, M; Wolfersdorf, M; Wössner, S, 1996)
"Three patients with ischaemic heart disease developed profound cardiac failure, hypotension and bradycardia during combined therapy with verapamil and beta-adrenergic blocking drugs."3.66Adverse interaction between beta-adrenergic blocking drugs and verapamil--report of three cases. ( Anderson, ST; Federman, J; Harper, RW; Laufer, E; Pitt, A; Wayne, VS, 1982)
" The other cases published are: 1) 10 cases with oxprenolol (including 5 cases of coma and 4 deaths), 2) 9 cases with acebutolol (2 deaths) including 5 with studies of the kinetics of the product (1 personal case), 3) 7 cases with pindolol (no bradycardia, good prognosis), 4) 6 cases (1 personal) with metoprolol (4 cases of massive ingestion with 1 death), 5) 3 cases with alprenolol (1 death), 6) 4 cases with sotalol (2 cases of turned apex, 1 death), 7) 1 case with atenolol."3.66[Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases]. ( Auzépy, P; Boukara, N; Giudicelli, JF; Richard, C, 1983)
"Beta-blockers substantially improve survival in patients with chronic heart failure (HF) with left ventricular systolic dysfunction, but concerns about cardiovascular adverse effects may deter physicians from prescribing this therapy."2.71Adverse effects of beta-blocker therapy for patients with heart failure: a quantitative overview of randomized trials. ( Coffey, CS; Curtis, JP; Foody, JM; Hebert, PR; Ko, DT; Krumholz, HM; Sedrakyan, A, 2004)
"The incidence of arrhythmias was less after metoprolol."2.67Effect of pre-operative metoprolol on cardiovascular and catecholamine response and bleeding during hysterectomy. ( Blom, L; Jakobsen, CJ, 1992)
"Metoprolol-treated patients had an improvement in mean exercise capacity by 3 mets (p less than ."2.66Improvement in symptoms and exercise tolerance by metoprolol in patients with dilated cardiomyopathy: a double-blind, randomized, placebo-controlled trial. ( Engelmeier, RS; Gunnar, RM; O'Connell, JB; Rad, N; Scanlon, PJ; Walsh, R, 1985)
"Amiodarone is an extremely potent drug which is effective for both supraventricular as well as ventricular arrhythmias."2.36New antiarrhythmic drugs. ( Hess, DS; Scheinman, MM, 1983)
"Amiodarone use was associated with higher metoprolol concentrations following adjustment for different covariates (p = ."1.91Impact of amiodarone use on metoprolol concentrations, α-OH-metoprolol concentrations, metoprolol dosing and heart rate: A cross-sectional study. ( Busseuil, D; de Denus, S; Dubé, MP; Gaulin, MJ; Jutras, M; Leclair, G; Meloche, M; Mongrain, I; Oussaïd, E; Pilon, MO; Robert, S; Tardif, JC, 2023)
" Insulin was infused for a total of approximately 37 hours, most of which was dosed at 10 U/kg/hour; following discontinuation, serial serum insulin levels were drawn and remained at supraphysiologic levels for at least 24 hours and well above reference range for multiple days thereafter."1.56Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report. ( Bangh, SA; Cole, JB; Corcoran, JN; Jacoby, KJ; Olives, TD, 2020)
"Ivabradine is a selective bradycardic agent that inhibits hyperpolarization-activated cyclic nucleotide-gated (HCN) channels."1.51Ivabradine preserves dynamic sympathetic control of heart rate despite inducing significant bradycardia in rats. ( Hayama, Y; Kawada, T; Nishikawa, T; Shimizu, S; Shishido, T; Sugimachi, M; Uemura, K; Yamamoto, H, 2019)
"Reflex tachycardia was greater during atropine than metoprolol blockade and the sum of the HR increase during selective blockade (21 and 22 bpm) was greater when compared with the control (no blockade, 16 +/- 2 vs 11 +/- 2 bpm)."1.29Autonomic nervous system control of the heart: endurance exercise training. ( Foresman, BH; Raven, PB; Shi, X; Stern, SA; Stevens, GH, 1995)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199014 (22.58)18.7374
1990's10 (16.13)18.2507
2000's21 (33.87)29.6817
2010's12 (19.35)24.3611
2020's5 (8.06)2.80

Authors

AuthorsStudies
Bannister, BE1
Parry, DR1
Pouliot, JD1
Xiao, SQ1
Ibarra, F1
Cruz, M1
Stone, KH1
Reynolds, K1
Davis, S1
Van Tassell, BW1
Gibson, CM1
Robert, S1
Pilon, MO1
Oussaïd, E1
Meloche, M1
Leclair, G1
Jutras, M1
Gaulin, MJ1
Mongrain, I1
Busseuil, D1
Tardif, JC2
Dubé, MP1
de Denus, S1
Corcoran, JN1
Jacoby, KJ1
Olives, TD1
Bangh, SA1
Cole, JB1
Muniyappa, A1
Goldschlager, N1
Calzadilla, A1
Badiye, A1
Ghodsizad, A1
Bernstein, J1
Campos, M1
Mirsaeidi, M1
Kawada, T1
Shimizu, S1
Uemura, K1
Hayama, Y1
Yamamoto, H1
Shishido, T1
Nishikawa, T1
Sugimachi, M1
Shin, J2
Gonzales, M1
Pletcher, MJ2
Bebawi, E1
Jouni, SS1
Tessier, AA1
Frenette, AJ1
Brindamour, D1
Doré, M1
Salomon, S1
Fausto, J1
Vaillant, F1
Lauzier, B1
Ruiz, M1
Shi, Y1
Lachance, D1
Rivard, ME1
Bolduc, V1
Thorin, E1
Des Rosiers, C1
Bahrainy, S1
Levy, WC1
Busey, JM1
Caldwell, JH1
Stratton, JR1
Bateman, BT1
Patorno, E1
Desai, RJ1
Seely, EW1
Mogun, H1
Maeda, A1
Fischer, MA1
Hernandez-Diaz, S1
Huybrechts, KF1
Caramelli, B1
Gualandro, DM1
Freitas, S1
Yu, PC1
Calderaro, D1
Keane, M1
Rolfo, F1
Bobbio, M1
Angeli, F1
Cavallini, C1
Lazebnik, LB1
Mikheeva, OM1
Drozdov, VN1
Petrakov, AV1
Sil'vestrova, SIu1
Alonso-Coello, P1
Alvarez, C1
Cruz, P1
Torán, L1
De Nadal, M1
Martínez, M1
Paniagua, P1
Mases, A1
Urrutia, G1
Hersh, EV1
Giannakopoulos, H1
Ramdas, S1
Riesenberg, LA1
Jasani, N1
Vág, J1
Hably, C1
Bartha, J1
Wnek, W1
Sia, S1
Ko, DT1
Hebert, PR1
Coffey, CS1
Curtis, JP1
Foody, JM1
Sedrakyan, A1
Krumholz, HM1
Höcht, C1
Di Verniero, C1
Opezzo, JA1
Taira, CA1
McCollum, DL1
Greene, JL1
McGuire, DK1
Steinwender, C1
Hofmann, R1
Kypta, A1
Leisch, F1
Marraffa, JM1
Lang, L1
Ong, G1
Lehmann, DF1
Thürmann, PA1
Haack, S1
Werner, U1
Szymanski, J1
Haase, G1
Drewelow, B1
Reimann, IR1
Hippius, M1
Siegmund, W1
May, K1
Hasford, J1
Triposkiadis, F1
Giamouzis, G1
Kelepeshis, G1
Sitafidis, G1
Skoularigis, J1
Demopoulos, V1
Goryachkina, K1
Burbello, A1
Boldueva, S1
Babak, S1
Bergman, U1
Bertilsson, L1
Sato, S1
Onalan, O1
Cumurcu, BE1
Bekar, L1
Weisswange, A3
Csapo, G2
Kalusche, D1
Keck, M1
Wayne, VS1
Harper, RW1
Laufer, E1
Federman, J1
Anderson, ST1
Pitt, A1
Auzépy, P1
Boukara, N1
Richard, C1
Giudicelli, JF1
Scheinman, MM1
Hess, DS1
Nylander, E2
Areskog, NH1
Roach, PJ1
Magee, MA1
Freedman, SB1
Sra, JS1
Jazayeri, MR1
Avitall, B1
Dhala, A1
Deshpande, S1
Blanck, Z1
Akhtar, M1
Shi, X1
Stevens, GH1
Foresman, BH1
Stern, SA1
Raven, PB1
König, F1
Häfele, M1
Hauger, B1
Löble, M1
Wössner, S1
Wolfersdorf, M1
Breithaupt-Grögler, K1
Gerhardt, G1
Lehmann, G1
Notter, T1
Belz, GG1
Liguori, GA1
Kahn, RL1
Gordon, J1
Gordon, MA1
Urban, MK1
Yörükoğlu, D1
Göktug, A1
Alanoğlu, Z1
Tulunay, M1
Roach , D1
Thakore , E1
Sheldon , R1
Teixeira, AL1
Fontoura, BF1
Freire-Maia, L1
Chiari, E1
Machado, CR1
Teixeira, MM1
Camargos, ER1
Lager, I1
Blohmé, G1
Smith, U1
Roskamm, H1
Boucher, M1
Chapuy, E1
Duchêne-Marullaz, P1
Dangovian, MI1
Jarandilla, R1
Frumin, H1
Jakobsen, CJ1
Blom, L1
Reggev, A1
Vollhardt, BR1
Ol'binskaia, LI1
Vartanova, OA1
Sinopal'nikov, AI1
Alekseev, VG1
Logunov, OV1
Leor, J1
Levartowsky, D1
Sharon, C1
Farfel, Z1
Engelmeier, RS1
O'Connell, JB1
Walsh, R1
Rad, N1
Scanlon, PJ1
Gunnar, RM1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
2%-Mepivacaine With Two Different Vasoconstrictors; 1:20.000 Levonordefrin or 1:100.000 Epinephrin for Local Anesthesia in Third Molar Surgery: A Comparative Randomized Clinical Trial[NCT02603198]30 participants (Anticipated)Interventional2014-08-31Active, not recruiting
Safety of Local Dental Anesthesia in Patients With Cardiac Channelopathies[NCT03182777]31 participants (Actual)Interventional2015-05-31Completed
Predicting the Occurence of Hypotensive Bradycardic Events in the Patients Undergoing Arthroscopic Shoulder Surgery in the Sitting Position Under Interscalene Brachial Plexus Block[NCT01926561]68 participants (Actual)Observational2011-08-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for metoprolol and Bradyarrhythmia

ArticleYear
[The POISE study].
    Giornale italiano di cardiologia (2006), 2008, Volume: 9, Issue:12

    Topics: Adrenergic beta-Antagonists; Bradycardia; Delayed-Action Preparations; Heart Arrest; Humans; Hyperte

2008
Beta-adrenergic blocking agents and dental vasoconstrictors.
    Dental clinics of North America, 2010, Volume: 54, Issue:4

    Topics: Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthetics, Local; Bradycardia; Drug Interactions;

2010
Beta-adrenergic blocking agents and dental vasoconstrictors.
    Dental clinics of North America, 2010, Volume: 54, Issue:4

    Topics: Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthetics, Local; Bradycardia; Drug Interactions;

2010
Beta-adrenergic blocking agents and dental vasoconstrictors.
    Dental clinics of North America, 2010, Volume: 54, Issue:4

    Topics: Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthetics, Local; Bradycardia; Drug Interactions;

2010
Beta-adrenergic blocking agents and dental vasoconstrictors.
    Dental clinics of North America, 2010, Volume: 54, Issue:4

    Topics: Adrenergic beta-Antagonists; Anesthesia, Dental; Anesthetics, Local; Bradycardia; Drug Interactions;

2010
New antiarrhythmic drugs.
    American journal of surgery, 1983, Volume: 145, Issue:6

    Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half

1983

Trials

12 trials available for metoprolol and Bradyarrhythmia

ArticleYear
[Atenolol and metoprolol differentiated therapy of patients with arterial hypertension complicated by pathology of the digestive tract organs].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2008, Issue:2

    Topics: Antihypertensive Agents; Atenolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Bradycardi

2008
Adverse effects of beta-blocker therapy for patients with heart failure: a quantitative overview of randomized trials.
    Archives of internal medicine, 2004, Jul-12, Volume: 164, Issue:13

    Topics: Adrenergic beta-Antagonists; Aged; Bisoprolol; Bradycardia; Carbazoles; Carvedilol; Dizziness; Fatig

2004
Acute hemodynamic effects of moderate doses of nebivolol versus metoprolol in patients with systolic heart failure.
    International journal of clinical pharmacology and therapeutics, 2007, Volume: 45, Issue:2

    Topics: Adrenergic beta-Antagonists; Benzopyrans; Blood Pressure; Bradycardia; Cardiac Output, Low; Dose-Res

2007
Inhibition of metoprolol metabolism and potentiation of its effects by paroxetine in routinely treated patients with acute myocardial infarction (AMI).
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:3

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antidepressive Agents, Second-Generation; Area

2008
Blood pressure and aortic elastic properties--verapamil SR/trandolapril compared to a metoprolol/hydrochlorothiazide combination therapy.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:8

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive

1998
The use of metoprolol and glycopyrrolate to prevent hypotensive/bradycardic events during shoulder arthroscopy in the sitting position under interscalene block.
    Anesthesia and analgesia, 1998, Volume: 87, Issue:6

    Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arthroscopy; Bradycardia; Double-Blind Method;

1998
Comparison of intravenous metoprolol, verapamil and diltiazem on the attenuation of haemodynamic changes associated with tracheal extubation.
    European journal of anaesthesiology, 1999, Volume: 16, Issue:7

    Topics: Adult; Anti-Arrhythmia Agents; Antihypertensive Agents; Blood Pressure; Bradycardia; Diastole; Dilti

1999
Effect of cardioselective and non-selective beta-blockade on the hypoglycaemic response in insulin-dependent diabetics.
    Lancet (London, England), 1979, Mar-03, Volume: 1, Issue:8114

    Topics: Adult; Blood Glucose; Blood Pressure; Bradycardia; Clinical Trials as Topic; Diabetes Mellitus; Dias

1979
Effect of pre-operative metoprolol on cardiovascular and catecholamine response and bleeding during hysterectomy.
    European journal of anaesthesiology, 1992, Volume: 9, Issue:3

    Topics: Administration, Oral; Adult; Anesthesia Recovery Period; Anesthesia, General; Arrhythmias, Cardiac;

1992
[Possibilities and limitations of selective beta 1 adrenergic receptor blockade in clinical practice].
    Terapevticheskii arkhiv, 1988, Volume: 60, Issue:8

    Topics: Adult; Aged; Bradycardia; Bronchi; Bronchial Spasm; Clinical Trials as Topic; Coronary Disease; Dose

1988
Improvement in symptoms and exercise tolerance by metoprolol in patients with dilated cardiomyopathy: a double-blind, randomized, placebo-controlled trial.
    Circulation, 1985, Volume: 72, Issue:3

    Topics: Adult; Bradycardia; Cardiomyopathy, Dilated; Clinical Trials as Topic; Exercise Test; Female; Heart

1985
Metoprolol in acute myocardial infarction. Arrhythmias. The MIAMI Trial Research Group.
    The American journal of cardiology, 1985, Nov-22, Volume: 56, Issue:14

    Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bradycardia; Clinical Trials as Topic; Humans; Metopro

1985

Other Studies

47 other studies available for metoprolol and Bradyarrhythmia

ArticleYear
Clinically Significant Bradycardia and Hypotension Following Consumption of Betel Leaf in a Patient Treated for Chronic Atrial Fibrillation.
    Journal of pharmacy practice, 2023, Volume: 36, Issue:2

    Topics: Aged; Atrial Fibrillation; Bradycardia; Diabetes Mellitus, Type 2; Female; Humans; Hypotension; Meto

2023
Intravenous Metoprolol Versus Diltiazem for Rate Control in Atrial Fibrillation.
    The Annals of pharmacotherapy, 2022, Volume: 56, Issue:8

    Topics: Atrial Fibrillation; Bradycardia; Calcium Channel Blockers; Diltiazem; Heart Rate; Humans; Hypotensi

2022
Comparison of new-onset post-operative atrial fibrillation between patients receiving carvedilol and metoprolol after off-pump coronary artery bypass graft surgery.
    General thoracic and cardiovascular surgery, 2023, Volume: 71, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Atrial Fibrillation; Bradycardia; Carvedilol; Coronary Artery By

2023
Impact of amiodarone use on metoprolol concentrations, α-OH-metoprolol concentrations, metoprolol dosing and heart rate: A cross-sectional study.
    Pharmacology research & perspectives, 2023, Volume: 11, Issue:5

    Topics: Adult; Amiodarone; Bradycardia; Cross-Sectional Studies; Cytochrome P-450 CYP2D6; Heart Rate; Humans

2023
Persistent Hyperinsulinemia Following High-Dose Insulin Therapy: A Case Report.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2020, Volume: 16, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Amlodipine; Bradycardia; Calcium Channel Blockers; Drug Admi

2020
Wide Complex Ventricular Rhythm in a Patient After Collapse.
    JAMA internal medicine, 2017, 06-01, Volume: 177, Issue:6

    Topics: Aged, 80 and over; Antihypertensive Agents; Arrhythmias, Cardiac; Bradycardia; Electrocardiography;

2017
A Young Woman with Bradycardia and Hypotension.
    Annals of the American Thoracic Society, 2018, Volume: 15, Issue:9

    Topics: Adrenergic beta-1 Receptor Antagonists; Analgesics, Opioid; Benzodiazepines; Bradycardia; Central Ne

2018
Ivabradine preserves dynamic sympathetic control of heart rate despite inducing significant bradycardia in rats.
    The journal of physiological sciences : JPS, 2019, Volume: 69, Issue:2

    Topics: Animals; Blood Pressure; Bradycardia; Heart Rate; Hyperpolarization-Activated Cyclic Nucleotide-Gate

2019
Risk of emergent bradycardia associated with initiation of immediate- or slow-release metoprolol.
    Pharmacotherapy, 2013, Volume: 33, Issue:12

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Bradycardia; California; Databases, Factual; D

2013
Risk of emergent bradycardia associated with the use of carvedilol and metoprolol in routine clinical practice.
    The American journal of medicine, 2013, Volume: 126, Issue:9

    Topics: Adrenergic alpha-1 Receptor Antagonists; Bradycardia; California; Carbazoles; Carvedilol; Comorbidit

2013
A metoprolol-terbinafine combination induced bradycardia.
    European journal of drug metabolism and pharmacokinetics, 2015, Volume: 40, Issue:3

    Topics: Bradycardia; Cytochrome P-450 CYP2D6; Drug Interactions; Drug Therapy, Combination; Heart Rate; Huma

2015
Unnecessary pacemaker: care coordination problems and language barriers.
    JAMA internal medicine, 2015, Volume: 175, Issue:4

    Topics: Aged; Anti-Arrhythmia Agents; Antihypertensive Agents; Atrioventricular Block; Bradycardia; Communic

2015
Ivabradine and metoprolol differentially affect cardiac glucose metabolism despite similar heart rate reduction in a mouse model of dyslipidemia.
    American journal of physiology. Heart and circulatory physiology, 2016, 10-01, Volume: 311, Issue:4

    Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Benzazepines; Bradycardia; Cardiovascular Agents; D

2016
Exercise training bradycardia is largely explained by reduced intrinsic heart rate.
    International journal of cardiology, 2016, Nov-01, Volume: 222

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adult; Age Factors; Aged; Autonomi

2016
Late Pregnancy β Blocker Exposure and Risks of Neonatal Hypoglycemia and Bradycardia.
    Pediatrics, 2016, Volume: 138, Issue:3

    Topics: Adrenergic beta-Antagonists; Atenolol; Bradycardia; Cohort Studies; Female; Humans; Hypertension; Hy

2016
Beta-blocker therapy in non-cardiac surgery.
    Lancet (London, England), 2008, Sep-27, Volume: 372, Issue:9644

    Topics: Adrenergic beta-Antagonists; Bradycardia; Cardiovascular Diseases; Causality; Comorbidity; Humans; H

2008
Beta-blocker therapy in non-cardiac surgery.
    Lancet (London, England), 2008, Sep-27, Volume: 372, Issue:9644

    Topics: Adrenergic beta-Antagonists; Bradycardia; Cardiovascular Diseases; Delayed-Action Preparations; Huma

2008
[Beta-blockers in patients undergoing noncardiac surgery: implications of the POISE study].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:4

    Topics: Adrenergic beta-Antagonists; Bradycardia; Contraindications; Female; Forecasting; Heart; Heart Arres

2009
Drug overdose with refractory bradycardia and hypotension.
    Delaware medical journal, 2011, Volume: 83, Issue:6

    Topics: Antihypertensive Agents; Bradycardia; Clonazepam; Diltiazem; Drug Overdose; Female; GABA Modulators;

2011
Inhibition of beta-1 receptor but not vagotomy can abolish the L-NAME evoked bradycardia in anesthetized rat.
    Physiological research, 2002, Volume: 51, Issue:3

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pres

2002
[The use of intra-aortic balloon counterpulsation in the treatment of severe hemodynamic instability from myocardial depressant drug overdose].
    Przeglad lekarski, 2003, Volume: 60, Issue:4

    Topics: Adult; Antihypertensive Agents; Bradycardia; Counterpulsation; Diltiazem; Drug Overdose; Fatal Outco

2003
Plasma concentrations of epinephrine need to be monitored in study of incidence of hypotensive/bradycardic events.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:2

    Topics: Bradycardia; Epinephrine; Humans; Hypotension; Intraoperative Complications; Metoprolol; Monitoring,

2004
Pharmacokinetic-pharmacodynamic properties of metoprolol in chronic aortic coarctated rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:1

    Topics: Animals; Aortic Coarctation; Blood Pressure; Bradycardia; Chronic Disease; Disease Models, Animal; D

2004
Severe sinus bradycardia after initiation of bupropion therapy: a probable drug-drug interaction with metoprolol.
    Cardiovascular drugs and therapy, 2004, Volume: 18, Issue:4

    Topics: Adrenergic beta-Antagonists; Arrhythmia, Sinus; Bradycardia; Bupropion; Dopamine Uptake Inhibitors;

2004
Recurrent symptomatic bradycardia due to secret ingestion of beta-blockers--a rare manifestation of cardiac Münchhausen syndrome.
    Wiener klinische Wochenschrift, 2005, Volume: 117, Issue:18

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Bradycardia; Female; Humans; Metoprolol; M

2005
Profound metoprolol-induced bradycardia precipitated by acetaminophen-propoxyphene.
    Clinical pharmacology and therapeutics, 2006, Volume: 79, Issue:3

    Topics: Acetaminophen; Adrenergic beta-Antagonists; Analgesics, Non-Narcotic; Analgesics, Opioid; Bradycardi

2006
Tolerability of beta-blockers metabolized via cytochrome P450 2D6 is sex-dependent.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Bradycardia; Cytochrome P-450 CYP2D6; Dose-Res

2006
Quantitative evaluation of ontogenetic change in heart rate and its autonomic regulation in newborn mice with the use of a noninvasive piezoelectric sensor.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Age Factors; Animals; Animals, Newborn; Atropine; Autonomic Nervous System; Baroreflex; Biosensing T

2008
Complete atrioventricular block associated with concomitant use of metoprolol and paroxetine.
    Mayo Clinic proceedings, 2008, Volume: 83, Issue:5

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atrioventricular Block; Atrioventricular Node;

2008
Electrophysiological studies with prenalterol.
    Acta medica Scandinavica. Supplementum, 1982, Volume: 659

    Topics: Adrenergic beta-Agonists; Atrial Fibrillation; Atrioventricular Node; Bradycardia; Bundle of His; Ca

1982
Adverse interaction between beta-adrenergic blocking drugs and verapamil--report of three cases.
    Australian and New Zealand journal of medicine, 1982, Volume: 12, Issue:4

    Topics: Adrenergic beta-Antagonists; Aged; Bradycardia; Coronary Disease; Drug Interactions; Drug Therapy, C

1982
[Acute poisoning caused by beta blockers in the adult. Apropos of 7 cases].
    Annales de cardiologie et d'angeiologie, 1983, Volume: 32, Issue:4

    Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Alcohol Drinking; Bradycardia; Coma; Dos

1983
New aspects on training bradycardia.
    Upsala journal of medical sciences, 1982, Volume: 87, Issue:1

    Topics: Adult; Animals; Bradycardia; Electrocardiography; Heart; Heart Rate; Humans; Hydroxydopamines; Metop

1982
Asystole and bradycardia during dipyridamole stress testing in patients receiving beta blockers.
    International journal of cardiology, 1993, Volume: 42, Issue:1

    Topics: Adrenergic beta-Antagonists; Atenolol; Bradycardia; Dipyridamole; Electrocardiography; Exercise Test

1993
Comparison of cardiac pacing with drug therapy in the treatment of neurocardiogenic (vasovagal) syncope with bradycardia or asystole.
    The New England journal of medicine, 1993, Apr-15, Volume: 328, Issue:15

    Topics: Adolescent; Adult; Aged; Bradycardia; Cardiac Pacing, Artificial; Disopyramide; Female; Follow-Up St

1993
Autonomic nervous system control of the heart: endurance exercise training.
    Medicine and science in sports and exercise, 1995, Volume: 27, Issue:10

    Topics: Adult; Atropine; Autonomic Nervous System; Blood Volume; Bradycardia; Cholinergic Antagonists; Drug

1995
[Bradycardia after beginning therapy with metoprolol and paroxetine].
    Psychiatrische Praxis, 1996, Volume: 23, Issue:5

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Second-Generation; Blood Pressure; Bradycardia;

1996
Beta-blockers for heart failure.
    The Medical letter on drugs and therapeutics, 2000, Jun-26, Volume: 42, Issue:1081

    Topics: Adrenergic beta-Antagonists; Bisoprolol; Bradycardia; Carbazoles; Carvedilol; Heart Failure; Humans;

2000
Origins of heart rate variability: autonomic blockade of large magnitude, transient bradycardia in conscious rabbits.
    The Canadian journal of cardiology, 2001, Volume: 17, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic beta-2 Receptor An

2001
Cardiac autonomic denervation and functional response to neurotoxins during acute experimental Chagas' disease in rats.
    Autonomic neuroscience : basic & clinical, 2001, Jun-20, Volume: 89, Issue:1-2

    Topics: Acetylcholine; Animals; Atropine; Bradycardia; Chagas Cardiomyopathy; Denervation; Heart; Heart Rate

2001
[Is bradycardia a contraindication?].
    Cardiology, 1978, Volume: 63 Suppl 1

    Topics: Adrenergic beta-Antagonists; Bradycardia; Heart Rate; Humans; Metoprolol

1978
[Effect of beta-receptor blocking agent in 2nd degree av-block: conduction study in 9 patients (author's transl)].
    Zeitschrift fur Kardiologie, 1978, Volume: 67, Issue:6

    Topics: Adolescent; Adult; Aged; Bradycardia; Electrocardiography; Female; Heart Block; Heart Conduction Sys

1978
Membrane stabilizing activity and beta-adrenoceptor antagonist-induced bradycardia in conscious dogs.
    European journal of pharmacology, 1992, Feb-18, Volume: 211, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Atrial Function; Bradycardia; Consciousness; Dogs; Dose-Respon

1992
Prolonged asystole during head-up tilt table testing after beta blockade.
    Pacing and clinical electrophysiology : PACE, 1992, Volume: 15, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Bradycardia; Female; Heart Arrest; Humans; Hypotension, Orthosta

1992
Training-induced bradycardia in rats on cardioselective and non-selective beta receptor blockade.
    Acta physiologica Scandinavica, 1985, Volume: 123, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Bradycardia; Female; Heart Rate; Metoprolol; Physical Exertion

1985
Bradycardia induced by an interaction between phenelzine and beta blockers.
    Psychosomatics, 1989,Winter, Volume: 30, Issue:1

    Topics: Aged; Angina Pectoris; Bradycardia; Depressive Disorder; Drug Interactions; Drug Therapy, Combinatio

1989
Amiodarone and beta-adrenergic blockers: an interaction with metoprolol but not with atenolol.
    American heart journal, 1988, Volume: 116, Issue:1 Pt 1

    Topics: Amiodarone; Atenolol; Bradycardia; Cardiomyopathy, Hypertrophic; Drug Interactions; Drug Therapy, Co

1988