metoprolol has been researched along with Becker Muscular Dystrophy in 4 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Secondary: changes of a) LV-FS from baseline, b) blood pressure, c), heart rate and autonomic function in ECG and Holter-ECG, e) cardiac biomarkers and neurohumeral serum parameters, f) quality of life, and g) adverse events." | 6.90 | Effect and safety of treatment with ACE-inhibitor Enalapril and β-blocker metoprolol on the onset of left ventricular dysfunction in Duchenne muscular dystrophy - a randomized, double-blind, placebo-controlled trial. ( Dittrich, S; Ebinger, F; Graf, E; Heilmann, A; Khalil, M; Kirschner, J; Korenke, C; Lange, M; Motz, R; Müller-Felber, W; Neudorf, U; Pattathu, J; Pozza, RD; Schara, U; Schröder, R; Stiller, B; Trollmann, R; von Au, K; von der Hagen, M; Weiss, K; Wiechmann, N; Wilichowski, E, 2019) |
| " Secondary: changes of a) LV-FS from baseline, b) blood pressure, c), heart rate and autonomic function in ECG and Holter-ECG, e) cardiac biomarkers and neurohumeral serum parameters, f) quality of life, and g) adverse events." | 2.90 | Effect and safety of treatment with ACE-inhibitor Enalapril and β-blocker metoprolol on the onset of left ventricular dysfunction in Duchenne muscular dystrophy - a randomized, double-blind, placebo-controlled trial. ( Dittrich, S; Ebinger, F; Graf, E; Heilmann, A; Khalil, M; Kirschner, J; Korenke, C; Lange, M; Motz, R; Müller-Felber, W; Neudorf, U; Pattathu, J; Pozza, RD; Schara, U; Schröder, R; Stiller, B; Trollmann, R; von Au, K; von der Hagen, M; Weiss, K; Wiechmann, N; Wilichowski, E, 2019) |
| "Most patients with Duchenne muscular dystrophy (DMD) will develop cardiomyopathy; however, the evidence for prophylactic treatment of children with cardiac medications is limited." | 1.42 | Absence of Cardiac Benefit with Early Combination ACE Inhibitor and Beta Blocker Treatment in mdx Mice. ( Blain, A; Blamire, AM; Greally, E; Laval, SH; MacGowan, GA; Straub, VW, 2015) |
| "Metoprolol was given orally (2." | 1.36 | Intolerance to ß-blockade in a mouse model of δ-sarcoglycan-deficient muscular dystrophy cardiomyopathy. ( Bauer, R; Blain, A; Bushby, K; Greally, E; Laval, S; Lochmüller, H; MacGowan, GA; Straub, V, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Razzoli, M | 1 |
| Lindsay, A | 1 |
| Law, ML | 1 |
| Chamberlain, CM | 1 |
| Southern, WM | 1 |
| Berg, M | 1 |
| Osborn, J | 1 |
| Engeland, WC | 1 |
| Metzger, JM | 1 |
| Ervasti, JM | 1 |
| Bartolomucci, A | 1 |
| Dittrich, S | 1 |
| Graf, E | 1 |
| Trollmann, R | 1 |
| Neudorf, U | 1 |
| Schara, U | 1 |
| Heilmann, A | 1 |
| von der Hagen, M | 1 |
| Stiller, B | 1 |
| Kirschner, J | 1 |
| Pozza, RD | 1 |
| Müller-Felber, W | 1 |
| Weiss, K | 1 |
| von Au, K | 1 |
| Khalil, M | 1 |
| Motz, R | 1 |
| Korenke, C | 1 |
| Lange, M | 1 |
| Wilichowski, E | 1 |
| Pattathu, J | 1 |
| Ebinger, F | 1 |
| Wiechmann, N | 1 |
| Schröder, R | 1 |
| Blain, A | 2 |
| Greally, E | 2 |
| Laval, SH | 1 |
| Blamire, AM | 1 |
| MacGowan, GA | 2 |
| Straub, VW | 1 |
| Bauer, R | 1 |
| Bushby, K | 1 |
| Lochmüller, H | 1 |
| Laval, S | 1 |
| Straub, V | 1 |
1 trial available for metoprolol and Becker Muscular Dystrophy
| Article | Year |
|---|---|
Effect and safety of treatment with ACE-inhibitor Enalapril and β-blocker metoprolol on the onset of left ventricular dysfunction in Duchenne muscular dystrophy - a randomized, double-blind, placebo-controlled trial.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Cardio | 2019 |
3 other studies available for metoprolol and Becker Muscular Dystrophy
| Article | Year |
|---|---|
Social stress is lethal in the mdx model of Duchenne muscular dystrophy.
Topics: Adrenergic beta-Antagonists; Animals; Arterial Pressure; Disease Models, Animal; Dystrophin; Gait Di | 2020 |
Absence of Cardiac Benefit with Early Combination ACE Inhibitor and Beta Blocker Treatment in mdx Mice.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Captopril; | 2015 |
Intolerance to ß-blockade in a mouse model of δ-sarcoglycan-deficient muscular dystrophy cardiomyopathy.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Animals; Disease Models | 2010 |