metoprolol has been researched along with Atherogenesis in 7 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been shown that oxidative stress may play an important role in the development of atherosclerosis, and carvedilol has the capacity of reducing oxidative stress." | 7.78 | Carvedilol reduces the severity of atherosclerosis in apolipoprotein E-deficient mice via reducing superoxide production. ( Fujita, M; Hirano, E; Kimura, T; Kishimoto, C; Shimada, K, 2012) |
| "Atherosclerosis was assessed in thoracic aorta and aortic root." | 5.40 | Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. ( Bergström, GM; Bernberg, E; Johansson, ME; Ulleryd, MA; Yang, LJ, 2014) |
| "Metoprolol treatment attenuated vessel positive remodeling and reduced vulnerability index (1." | 5.35 | Effect of metoprolol on vulnerable plaque in rabbits by changing shear stress around plaque and reducing inflammation. ( Changjiang, L; Guihua, J; Huixia, L; Liang, C; Mei, Z; Runyi, S; Xiaobo, H; Xiaojun, C; Xiaonan, L; Xinsheng, X; Yanen, Z; Yun, Z, 2009) |
| "It has been shown that oxidative stress may play an important role in the development of atherosclerosis, and carvedilol has the capacity of reducing oxidative stress." | 3.78 | Carvedilol reduces the severity of atherosclerosis in apolipoprotein E-deficient mice via reducing superoxide production. ( Fujita, M; Hirano, E; Kimura, T; Kishimoto, C; Shimada, K, 2012) |
| "Asymptomatic carotid stenosis is when this narrowing occurs in people without a history or symptoms of this disease." | 3.01 | Pharmacological interventions for asymptomatic carotid stenosis. ( Cassola, N; Clezar, CN; Flumignan, CD; Flumignan, RL; Nakano, LC; Trevisani, VF, 2023) |
| "Mice treated with metoprolol experienced a reduced heart rate with no difference in blood pressure." | 1.91 | Beta1-receptor blockade attenuates atherosclerosis progression following traumatic brain injury in apolipoprotein E deficient mice. ( Eitzman, DT; Guo, C; Lawrence, DA; Silaghi, P; Su, EJ; Venugopal, J; Wang, J, 2023) |
| "Atherosclerosis was assessed in thoracic aorta and aortic root." | 1.40 | Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. ( Bergström, GM; Bernberg, E; Johansson, ME; Ulleryd, MA; Yang, LJ, 2014) |
| "Metoprolol treatment attenuated vessel positive remodeling and reduced vulnerability index (1." | 1.35 | Effect of metoprolol on vulnerable plaque in rabbits by changing shear stress around plaque and reducing inflammation. ( Changjiang, L; Guihua, J; Huixia, L; Liang, C; Mei, Z; Runyi, S; Xiaobo, H; Xiaojun, C; Xiaonan, L; Xinsheng, X; Yanen, Z; Yun, Z, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Venugopal, J | 1 |
| Silaghi, P | 1 |
| Su, EJ | 1 |
| Guo, C | 1 |
| Lawrence, DA | 1 |
| Eitzman, DT | 1 |
| Clezar, CN | 1 |
| Flumignan, CD | 1 |
| Cassola, N | 1 |
| Nakano, LC | 1 |
| Trevisani, VF | 1 |
| Flumignan, RL | 1 |
| Ulleryd, MA | 1 |
| Bernberg, E | 1 |
| Yang, LJ | 1 |
| Bergström, GM | 1 |
| Johansson, ME | 1 |
| Liang, C | 1 |
| Xiaonan, L | 1 |
| Xiaojun, C | 1 |
| Changjiang, L | 1 |
| Xinsheng, X | 1 |
| Guihua, J | 1 |
| Xiaobo, H | 1 |
| Yanen, Z | 1 |
| Runyi, S | 1 |
| Huixia, L | 1 |
| Yun, Z | 1 |
| Mei, Z | 1 |
| Bolduc, V | 1 |
| Drouin, A | 1 |
| Gillis, MA | 1 |
| Duquette, N | 1 |
| Thorin-Trescases, N | 1 |
| Frayne-Robillard, I | 1 |
| Des Rosiers, C | 1 |
| Tardif, JC | 1 |
| Thorin, E | 1 |
| Shimada, K | 1 |
| Hirano, E | 1 |
| Kimura, T | 1 |
| Fujita, M | 1 |
| Kishimoto, C | 1 |
| Baumhäkel, M | 1 |
| Schlimmer, N | 1 |
| Büyükafsar, K | 1 |
| Arikan, O | 1 |
| Böhm, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Pharmacological Heart Rate Reduction on Visco-elastic Properties of the Arterial Wall (BRADYVASC)[NCT02584439] | Phase 3 | 30 participants (Anticipated) | Interventional | 2015-10-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for metoprolol and Atherogenesis
| Article | Year |
|---|---|
Pharmacological interventions for asymptomatic carotid stenosis.
Topics: Aspirin; Atherosclerosis; Atorvastatin; Carotid Stenosis; Chlorthalidone; Fluvastatin; Hemorrhage; H | 2023 |
6 other studies available for metoprolol and Atherogenesis
| Article | Year |
|---|---|
Beta1-receptor blockade attenuates atherosclerosis progression following traumatic brain injury in apolipoprotein E deficient mice.
Topics: Adrenergic beta-Antagonists; Animals; Atherosclerosis; Blood Pressure; Brain Injuries, Traumatic; Di | 2023 |
Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis | 2014 |
Effect of metoprolol on vulnerable plaque in rabbits by changing shear stress around plaque and reducing inflammation.
Topics: Abdomen; Adrenergic beta-Antagonists; Animals; Aorta; Atherosclerosis; Cytokines; Gene Expression Re | 2009 |
Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice.
Topics: Animals; Anti-Arrhythmia Agents; Apolipoproteins B; Atherosclerosis; Benzazepines; Carotid Arteries; | 2011 |
Carvedilol reduces the severity of atherosclerosis in apolipoprotein E-deficient mice via reducing superoxide production.
Topics: Adrenergic beta-Antagonists; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Blood Pressure; Car | 2012 |
Nebivolol, but not metoprolol, improves endothelial function of the corpus cavernosum in apolipoprotein e-knockout mice.
Topics: Adrenergic beta-Antagonists; Animals; Antioxidants; Aorta, Thoracic; Apolipoproteins E; Atherosclero | 2008 |