Page last updated: 2024-10-31
metoprolol and Asthma
metoprolol has been researched along with Asthma in 39 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the effects of an osmotic release oral drug delivery system of metoprolol on the changes induced by cumulative doses of inhaled salbutamol on bronchomotor tone, skeletal muscle, and the circulatory system after single (day 1) and multiple (day 7) dosing in 18 hypertensive asthmatic patients (forced expiratory volume in 1 second > 50% predicted; diastolic blood pressure > 90 mm Hg)." | 9.07 | Osmotic release oral drug delivery system of metoprolol in hypertensive asthmatic patients. Pharmacodynamic effects on beta 2-adrenergic receptors. ( Bauer, K; Kaik, B; Kaik, G, 1994) |
| "The effects of labetalol, metoprolol, and placebo on pulmonary function and their interaction with isoproterenol were evaluated in 18 patients with reversible bronchial asthma [isoproterenol-induced increase in forced expiratory volume in 1 second (FEV1) of greater than or equal to 15%]." | 9.06 | Effect of single doses of labetalol, metoprolol, and placebo on ventilatory function in patients with bronchial asthma: interaction with isoproterenol. ( Falliers, CJ; Medakovic, M; Vincent, ME, 1986) |
| "The beta 2-adrenoceptor mediated effects on ventilatory capacity, forced expiratory volume in one second (FEV1), forced ventilatory capacity (FVC), heart rate, and skeletal muscle tremor of a new controlled-release (CR) formulation of metoprolol, 100 mg and 200 mg, and of atenolol tablets, 100 mg, were studied in eight asthmatic patients." | 9.06 | Controlled-release metoprolol compared with atenolol in asthmatic patients: interaction with terbutaline. ( Dahlöf, C; Löfdahl, CG; Olofsson, B; Svedmyr, N; Westergren, G, 1988) |
| " In this double-blind, three-way, crossover study, the effects of relatively high single doses of dilevalol (400 mg), metoprolol (200 mg), a placebo on pulmonary function and their interaction with isoproterenol (160 and 480 micrograms) were evaluated in 16 patients with reversible bronchial asthma [isoproterenol-induced increase in forced expiratory volume in 1 s (FEV1) of greater than or equal to 15%]." | 9.06 | The effects of dilevalol, metoprolol, and placebo on ventilatory function in asthmatics. ( Blasucci, DJ; Chodosh, S; Tuck, J, 1988) |
| "The effects on standing heart rate and respiratory function of two relatively selective beta 1-adrenoceptor antagonists, metoprolol and bevantolol, were compared in a double-blind, randomized, crossover study of 16 patients with asthma." | 9.06 | Respiratory and cardiac effects of metoprolol and bevantolol in patients with asthma. ( Ahmad, D; Carruthers, SG; Darke, AC; Parsons, J; Wilcox, PG, 1986) |
| "In a double blind, placebo-controlled study the ventilatory effects of the beta 1-selective receptor blockers bisoprolol (EMD 33512) and metoprolol and their interactions with the beta 2-adrenoceptor agonist terbutaline were investigated in 8 asthmatic patients." | 9.05 | Ventilatory effects of beta 1-receptor-selective blockade with bisoprolol and metoprolol in asthmatic patients. ( Folgering, HT; Lammers, JW; van Herwaarden, CL, 1984) |
| "A double-blind, placebo-controlled study of the haemodynamic and ventilatory effects of two beta 1-selective adrenoceptor blockers and their interaction with the beta 2-adrenoceptor agonist terbutaline was carried out in eight asthmatic patients." | 9.05 | Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients. ( Greefhorst, AP; van Herwaarden, CL, 1982) |
| "The effect of the beta 1-selective adrenoceptor blocker, metoprolol, on ventilatory function was studied in eight asthmatic patients in relation to the plasma level of the agent following its administration in ordinary and slow-release tablets." | 9.05 | Ventilatory effects of ordinary and slow-release tablets of metoprolol in asthmatic patients. ( van den Bergh, JH; van Herwaarden, CL, 1981) |
| "Eight asthmatic patients were investigated in a double-blind cross-over study after oral administration of 100 mg atenolol, 10 mg metoprolol and placebo." | 9.05 | Cardioselectivity of atenolol and metoprolol. A study in asthmatic patients. ( Löfdahl, CG; Svedmyr, N, 1981) |
| "Studies of metoprolol in asthmatic patients showed beta 1-selective blocking properties on the adrenergic receptor." | 9.04 | Influence of metoprolol on hemodynamics and respiratory function in asthmatic patients. ( Hida, W; Mue, S; Ohmi, T; Sasaki, T; Shibahara, S; Suzuki, S; Takahashi, M; Takishima, T; Yamauchi, K, 1979) |
| " We discuss the case of a patient with new-onset atrial fibrillation receiving metoprolol for rate control on a background of pseudoephedrine use for allergic rhinitis leading to acute myocardial infarction from multivessel coronary vasospasm." | 7.85 | Acute Myocardial Infarction from Coronary Vasospasm Precipitated by Pseudoephedrine and Metoprolol Use. ( Goldsweig, AM; Malm, BJ; Meoli, EM, 2017) |
| "An integrated pharmacokinetic-pharmacodynamic model was used to quantify the beta 2-blocking activity of metoprolol in seven asthmatic patients." | 7.68 | Quantification of metoprolol beta 2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamic modelling. ( Braat, MC; Jonkers, RE; van Boxtel, CJ, 1992) |
| "The respiratory tolerance of the beta 1-adrenoceptor-selective blockers bisoprolol and metoprolol was investigated in eight male asthmatic patients." | 7.67 | Respiratory tolerance of bisoprolol and metoprolol in asthmatic patients. ( Folgering, HT; Lammers, JW; van Herwaarden, CL, 1986) |
| "The effects of chronic cimetidine therapy on the pharmacodynamic properties of atenolol and metoprolol were assessed in eight asthmatic patients using a placebo-controlled trial." | 7.67 | The effect of cimetidine on the relative cardioselectivity of atenolol and metoprolol in asthmatic patients. ( Barker, NP; Ellis, ME; Fitzsimons, TJ; Hussain, M; Webb, AK, 1984) |
| "Twenty patients with severe or medium severe asthma were given atenolol (Atenol ICI-Pharma) and/or metoprolol (Seloken Hässle) for tachycardia, hyperkinetic tremor, arterial hypertension or symptoms of angina pectoris." | 7.66 | Comparison of the effect of the beta1-blocking drugs atenolol and metoprolol on bronchial asthma. ( Carlson, C; Järvinen, KA, 1978) |
| " After the terbutaline dose-response curve was determined, terbutaline was inhaled three times in increasing doses." | 6.65 | Pafenolol, a highly selective beta 1-adrenoceptor-antagonist, in asthmatic patients: interaction with terbutaline. ( Löfdahl, CG; Marlin, GE; Svedmyr, N, 1983) |
| "This study investigated the effects of an osmotic release oral drug delivery system of metoprolol on the changes induced by cumulative doses of inhaled salbutamol on bronchomotor tone, skeletal muscle, and the circulatory system after single (day 1) and multiple (day 7) dosing in 18 hypertensive asthmatic patients (forced expiratory volume in 1 second > 50% predicted; diastolic blood pressure > 90 mm Hg)." | 5.07 | Osmotic release oral drug delivery system of metoprolol in hypertensive asthmatic patients. Pharmacodynamic effects on beta 2-adrenergic receptors. ( Bauer, K; Kaik, B; Kaik, G, 1994) |
| "The beta 2-adrenoceptor mediated effects on ventilatory capacity, forced expiratory volume in one second (FEV1), forced ventilatory capacity (FVC), heart rate, and skeletal muscle tremor of a new controlled-release (CR) formulation of metoprolol, 100 mg and 200 mg, and of atenolol tablets, 100 mg, were studied in eight asthmatic patients." | 5.06 | Controlled-release metoprolol compared with atenolol in asthmatic patients: interaction with terbutaline. ( Dahlöf, C; Löfdahl, CG; Olofsson, B; Svedmyr, N; Westergren, G, 1988) |
| " In this double-blind, three-way, crossover study, the effects of relatively high single doses of dilevalol (400 mg), metoprolol (200 mg), a placebo on pulmonary function and their interaction with isoproterenol (160 and 480 micrograms) were evaluated in 16 patients with reversible bronchial asthma [isoproterenol-induced increase in forced expiratory volume in 1 s (FEV1) of greater than or equal to 15%]." | 5.06 | The effects of dilevalol, metoprolol, and placebo on ventilatory function in asthmatics. ( Blasucci, DJ; Chodosh, S; Tuck, J, 1988) |
| "The effects of labetalol, metoprolol, and placebo on pulmonary function and their interaction with isoproterenol were evaluated in 18 patients with reversible bronchial asthma [isoproterenol-induced increase in forced expiratory volume in 1 second (FEV1) of greater than or equal to 15%]." | 5.06 | Effect of single doses of labetalol, metoprolol, and placebo on ventilatory function in patients with bronchial asthma: interaction with isoproterenol. ( Falliers, CJ; Medakovic, M; Vincent, ME, 1986) |
| "The effects on standing heart rate and respiratory function of two relatively selective beta 1-adrenoceptor antagonists, metoprolol and bevantolol, were compared in a double-blind, randomized, crossover study of 16 patients with asthma." | 5.06 | Respiratory and cardiac effects of metoprolol and bevantolol in patients with asthma. ( Ahmad, D; Carruthers, SG; Darke, AC; Parsons, J; Wilcox, PG, 1986) |
| "In a randomized, blind crossover study in 14 hypertensive patients with asthma, involving placebo and chronically administered (3 weeks) equipotent beta1-blocking doses of atenolol 100 mg once daily and metoprolol 100 mg bid, atenolol and metoprolol produced a similar fall in blood pressure." | 5.05 | Asthma and beta-blockers. ( Chatterjee, SS; Cruickshank, JM; Lawrence, DS; Sahay, JN, 1982) |
| "A double-blind, placebo-controlled study of the haemodynamic and ventilatory effects of two beta 1-selective adrenoceptor blockers and their interaction with the beta 2-adrenoceptor agonist terbutaline was carried out in eight asthmatic patients." | 5.05 | Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients. ( Greefhorst, AP; van Herwaarden, CL, 1982) |
| "Eight asthmatic patients were investigated in a double-blind cross-over study after oral administration of 100 mg atenolol, 10 mg metoprolol and placebo." | 5.05 | Cardioselectivity of atenolol and metoprolol. A study in asthmatic patients. ( Löfdahl, CG; Svedmyr, N, 1981) |
| "The effects on ventilation of the non-selective beta-blocker propranolol, and the relatively cardioselective beta-blocker, metoprolol, were compared in a randomized single-blind crossover study in 16 patients with asthma, bronchitis and emphysema (American Thoracic Society criteria)." | 5.05 | Influence of cardioselectivity and respiratory disease on pulmonary responsiveness to beta-blockade. ( Ahmad, D; Carruthers, SG; Clague, HW, 1984) |
| "The effect of the beta 1-selective adrenoceptor blocker, metoprolol, on ventilatory function was studied in eight asthmatic patients in relation to the plasma level of the agent following its administration in ordinary and slow-release tablets." | 5.05 | Ventilatory effects of ordinary and slow-release tablets of metoprolol in asthmatic patients. ( van den Bergh, JH; van Herwaarden, CL, 1981) |
| "In a double blind, placebo-controlled study the ventilatory effects of the beta 1-selective receptor blockers bisoprolol (EMD 33512) and metoprolol and their interactions with the beta 2-adrenoceptor agonist terbutaline were investigated in 8 asthmatic patients." | 5.05 | Ventilatory effects of beta 1-receptor-selective blockade with bisoprolol and metoprolol in asthmatic patients. ( Folgering, HT; Lammers, JW; van Herwaarden, CL, 1984) |
| "Studies of metoprolol in asthmatic patients showed beta 1-selective blocking properties on the adrenergic receptor." | 5.04 | Influence of metoprolol on hemodynamics and respiratory function in asthmatic patients. ( Hida, W; Mue, S; Ohmi, T; Sasaki, T; Shibahara, S; Suzuki, S; Takahashi, M; Takishima, T; Yamauchi, K, 1979) |
| "In a double-blind, within-patient, randomized study, 12 mild asthmatics were given single oral doses of propranolol (80 mg), metoprolol (100 mg), timolol (10 mg), or placebo." | 5.04 | Selectivity of beta adrenoreceptor antagonist drugs assessed by histamine bronchial provocation. ( Anderton, RC; Frith, PA; Hargreave, FE; Kumana, CR; Newhouse, MT; Ruffin, RE, 1979) |
| "Ninety-nine patients took part in a multicentre, long-term study of metoprolol in the treatment of hypertension." | 5.04 | Results from a multicentre trial of metoprolol and a study of hypertensive patients with chronic obstructive lung disease. ( Assaykeen, TA; Hua, AS; Kincaid-Smith, PS; Nyberg, G, 1978) |
| " We discuss the case of a patient with new-onset atrial fibrillation receiving metoprolol for rate control on a background of pseudoephedrine use for allergic rhinitis leading to acute myocardial infarction from multivessel coronary vasospasm." | 3.85 | Acute Myocardial Infarction from Coronary Vasospasm Precipitated by Pseudoephedrine and Metoprolol Use. ( Goldsweig, AM; Malm, BJ; Meoli, EM, 2017) |
| "To assess efficacy and safety of selective beta-adrenoblockers (BAB) metoprolol succinate and nebivolol in patients with arterial hypertension (AH) and/or IHD associated with bronchoobstructive syndrome (BOS)." | 3.74 | [Administration of cardioselective beta-adrenoblockers in patients with arterial hypertension and/or ischemic heart disease associated with bronchoobstructive syndrome]. ( Litvinova, IV; Mikolkin, VI; Ovcharenko, SI, 2007) |
| "An integrated pharmacokinetic-pharmacodynamic model was used to quantify the beta 2-blocking activity of metoprolol in seven asthmatic patients." | 3.68 | Quantification of metoprolol beta 2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamic modelling. ( Braat, MC; Jonkers, RE; van Boxtel, CJ, 1992) |
| " Despite concern about the use of a beta-blocker in a patient with asthma, pre-operative tachycardia was successfully treated with the beta-1-selective adrenoreceptor antagonist, metoprolol." | 3.68 | Use of beta-blockade in a patient with phaeochromocytoma and asthma. ( Bevan, EG; McInnes, GT, 1992) |
| "The effects of chronic cimetidine therapy on the pharmacodynamic properties of atenolol and metoprolol were assessed in eight asthmatic patients using a placebo-controlled trial." | 3.67 | The effect of cimetidine on the relative cardioselectivity of atenolol and metoprolol in asthmatic patients. ( Barker, NP; Ellis, ME; Fitzsimons, TJ; Hussain, M; Webb, AK, 1984) |
| "The respiratory tolerance of the beta 1-adrenoceptor-selective blockers bisoprolol and metoprolol was investigated in eight male asthmatic patients." | 3.67 | Respiratory tolerance of bisoprolol and metoprolol in asthmatic patients. ( Folgering, HT; Lammers, JW; van Herwaarden, CL, 1986) |
| "Twenty patients with severe or medium severe asthma were given atenolol (Atenol ICI-Pharma) and/or metoprolol (Seloken Hässle) for tachycardia, hyperkinetic tremor, arterial hypertension or symptoms of angina pectoris." | 3.66 | Comparison of the effect of the beta1-blocking drugs atenolol and metoprolol on bronchial asthma. ( Carlson, C; Järvinen, KA, 1978) |
| "Metoprolol, a cardioselective beta-blocker, was used in two asthmatic, thyrotoxic patients in preparation for thyroidectomy." | 3.66 | The use of a selective beta-adrenergic receptor blocker for the preoperative preparation of thyrotoxic patients. ( Dial, P; Hastings, PR, 1982) |
| " After the terbutaline dose-response curve was determined, terbutaline was inhaled three times in increasing doses." | 2.65 | Pafenolol, a highly selective beta 1-adrenoceptor-antagonist, in asthmatic patients: interaction with terbutaline. ( Löfdahl, CG; Marlin, GE; Svedmyr, N, 1983) |
| "Other comorbidities included bronchial asthma, chronic sinusitis, ischemic heart disease, mild aortic stenosis, arterial hypertension, and degenerative thoracic spine disease." | 1.72 | Torasemide-induced Vascular Purpura in the Course of Eosinophilic Granulomatosis with Polyangiitis. ( Bergler-Czop, B; Frątczak, A; Miziołek, B; Polak, K, 2022) |
| "Metoprolol and atenolol were generally well tolerated except at higher doses such as metoprolol >100 mg daily." | 1.38 | Cardioselective beta-blocker treatment of hypertension in patients with asthma: when do benefits outweigh risks? ( Self, TH; Soberman, JE; Wallace, JL, 2012) |
Research
Studies (39)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (74.36) | 18.7374 |
| 1990's | 4 (10.26) | 18.2507 |
| 2000's | 2 (5.13) | 29.6817 |
| 2010's | 3 (7.69) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Frątczak, A | 1 |
| Polak, K | 1 |
| Miziołek, B | 1 |
| Bergler-Czop, B | 1 |
| Meoli, EM | 1 |
| Goldsweig, AM | 1 |
| Malm, BJ | 1 |
| Erokhina, IL | 1 |
| Voronchikhin, PA | 1 |
| Okovityĭ, SV | 1 |
| Emel'ianova, OI | 1 |
| Self, TH | 1 |
| Wallace, JL | 1 |
| Soberman, JE | 1 |
| Lin, R | 1 |
| Peng, H | 1 |
| Nguyen, LP | 1 |
| Dudekula, NB | 1 |
| Shardonofsky, F | 1 |
| Knoll, BJ | 1 |
| Parra, S | 1 |
| Bond, RA | 1 |
| Ovcharenko, SI | 1 |
| Litvinova, IV | 1 |
| Mikolkin, VI | 1 |
| Greefhorst, AP | 3 |
| van Herwaarden, CL | 7 |
| Löfdahl, CG | 6 |
| Lawrence, DS | 1 |
| Sahay, JN | 1 |
| Chatterjee, SS | 1 |
| Cruickshank, JM | 1 |
| Marlin, GE | 3 |
| Svedmyr, N | 5 |
| Lammers, JW | 2 |
| Folgering, HT | 2 |
| Clague, HW | 1 |
| Ahmad, D | 2 |
| Carruthers, SG | 2 |
| Yukawa, T | 1 |
| Numao, T | 1 |
| Motojima, S | 1 |
| Fukuda, T | 1 |
| Ikemori, R | 1 |
| Makino, S | 1 |
| Shimizu, T | 1 |
| Hayashi, T | 1 |
| Ellis, ME | 1 |
| Hussain, M | 1 |
| Webb, AK | 1 |
| Barker, NP | 1 |
| Fitzsimons, TJ | 1 |
| Dial, P | 1 |
| Hastings, PR | 1 |
| van den Bergh, JH | 2 |
| Bauer, K | 1 |
| Kaik, G | 1 |
| Kaik, B | 1 |
| Szmidt, M | 1 |
| Minc, P | 1 |
| Wasiak, W | 1 |
| Ruffin, RE | 1 |
| Frith, PA | 1 |
| Anderton, RC | 1 |
| Kumana, CR | 1 |
| Newhouse, MT | 1 |
| Hargreave, FE | 1 |
| Anderson, EG | 1 |
| Calcraft, B | 1 |
| Jariwalla, AG | 1 |
| Al-Zaibak, M | 1 |
| Formgren, H | 1 |
| Hua, AS | 1 |
| Assaykeen, TA | 1 |
| Nyberg, G | 1 |
| Kincaid-Smith, PS | 1 |
| Riley, T | 1 |
| Pleet, AB | 1 |
| Mue, S | 1 |
| Sasaki, T | 1 |
| Shibahara, S | 1 |
| Takahashi, M | 1 |
| Ohmi, T | 1 |
| Yamauchi, K | 1 |
| Suzuki, S | 1 |
| Hida, W | 1 |
| Takishima, T | 1 |
| Carlson, C | 1 |
| Järvinen, KA | 1 |
| Braat, MC | 1 |
| Jonkers, RE | 1 |
| van Boxtel, CJ | 1 |
| Bevan, EG | 1 |
| McInnes, GT | 1 |
| Sinopal'nikov, AI | 1 |
| Ol'binskaia, LI | 1 |
| Alekseev, VG | 1 |
| Chodosh, S | 1 |
| Tuck, J | 1 |
| Blasucci, DJ | 1 |
| Dahlöf, C | 1 |
| Westergren, G | 1 |
| Olofsson, B | 1 |
| Falliers, CJ | 1 |
| Vincent, ME | 1 |
| Medakovic, M | 1 |
| Wilcox, PG | 1 |
| Darke, AC | 1 |
| Parsons, J | 1 |
Clinical Trials (2)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Any Steroid Sparing Effect of Beta Blocker Therapy on Airway Hyper-responsiveness in Stable, Mild to Moderate Asthmatics[NCT01544634] | Phase 2 | 16 participants (Actual) | Interventional | 2012-04-04 | Completed | ||
| Heart Rate Lowering Efficacy and Respiratory Safety of Ivabradine in Patients With Obstructive Airway Disease[NCT01365286] | Phase 4 | 40 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Trials
19 trials available for metoprolol and Asthma
| Article | Year |
|---|---|
Comparative study of the ventilatory effects of three beta 1-selective blocking agents in asthmatic patients.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Asthma; Atenolol; Bronchi; Clinical Trials as Topic; | 1981 |
Selectivity of beta-adrenoceptor agonists and antagonists in asthmatics.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Asthma; Atenolol; Blood Pressure; Cl | 1982 |
Asthma and beta-blockers.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Asthma; Atenolol; Clinical Trials as Topic; Double-B | 1982 |
Pafenolol, a highly selective beta 1-adrenoceptor-antagonist, in asthmatic patients: interaction with terbutaline.
Topics: Adrenergic beta-Antagonists; Aged; Asthma; Dose-Response Relationship, Drug; Double-Blind Method; Dr | 1983 |
The effects of pafenolol and metoprolol on ventilatory function and haemodynamics during exercise by asthmatic patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Asthma; Blood Pressure; Female; Forced Expiratory Volume; | 1983 |
Ventilatory effects of beta 1-receptor-selective blockade with bisoprolol and metoprolol in asthmatic patients.
Topics: Adrenergic beta-Antagonists; Adult; Asthma; Bisoprolol; Blood Pressure; Forced Expiratory Volume; He | 1984 |
Influence of cardioselectivity and respiratory disease on pulmonary responsiveness to beta-blockade.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Asthma; Bronchitis; Female; Heart; Humans; Isoproterenol; | 1984 |
Cardioselectivity of atenolol and metoprolol. A study in asthmatic patients.
Topics: Adult; Aged; Asthma; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female | 1981 |
Ventilatory and haemodynamic effects of terbutaline infusion during beta 1-selective blockade with metoprolol and acebutolol in asthmatic patients.
Topics: Acebutolol; Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory | 1982 |
Ventilatory effects of ordinary and slow-release tablets of metoprolol in asthmatic patients.
Topics: Adolescent; Adult; Asthma; Delayed-Action Preparations; Female; Forced Expiratory Volume; Heart Rate | 1981 |
Osmotic release oral drug delivery system of metoprolol in hypertensive asthmatic patients. Pharmacodynamic effects on beta 2-adrenergic receptors.
Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Adult; Albuterol; Asthma; Atenolol; Double- | 1994 |
[Comparison of the influence of celiprolol, metoprolol and atenolol on pulmonary ventilation in patients with asthma].
Topics: Adrenergic beta-Antagonists; Adult; Area Under Curve; Asthma; Atenolol; Celiprolol; Female; Hemodyna | 1999 |
Selectivity of beta adrenoreceptor antagonist drugs assessed by histamine bronchial provocation.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Airway Resistance; Asthma; Double-Blind Method; Drug | 1979 |
Results from a multicentre trial of metoprolol and a study of hypertensive patients with chronic obstructive lung disease.
Topics: Adult; Aged; Antihypertensive Agents; Asthma; Chronic Disease; Clinical Trials as Topic; Drug Therap | 1978 |
Influence of metoprolol on hemodynamics and respiratory function in asthmatic patients.
Topics: Asthma; Double-Blind Method; Female; Hemodynamics; Humans; Isoproterenol; Male; Metoprolol; Placebos | 1979 |
The effects of dilevalol, metoprolol, and placebo on ventilatory function in asthmatics.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Asthma; Female; Forced Expiratory Volume; Hemo | 1988 |
Controlled-release metoprolol compared with atenolol in asthmatic patients: interaction with terbutaline.
Topics: Adult; Aged; Asthma; Atenolol; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind M | 1988 |
Effect of single doses of labetalol, metoprolol, and placebo on ventilatory function in patients with bronchial asthma: interaction with isoproterenol.
Topics: Adult; Asthma; Blood Pressure; Double-Blind Method; Drug Interactions; Female; Heart Rate; Humans; L | 1986 |
Respiratory and cardiac effects of metoprolol and bevantolol in patients with asthma.
Topics: Administration, Oral; Adult; Aged; Asthma; Double-Blind Method; Drug Evaluation; Female; Heart Rate; | 1986 |
Other Studies
20 other studies available for metoprolol and Asthma
| Article | Year |
|---|---|
Torasemide-induced Vascular Purpura in the Course of Eosinophilic Granulomatosis with Polyangiitis.
Topics: Adolescent; Aged; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Antinuclear; Antihypertensive | 2022 |
Acute Myocardial Infarction from Coronary Vasospasm Precipitated by Pseudoephedrine and Metoprolol Use.
Topics: Anti-Arrhythmia Agents; Asthma; Atrial Fibrillation; Bronchodilator Agents; Coronary Angiography; Co | 2017 |
[Reaction of population of pulmonary mast cells in rat bronchial asthma under the effect of β-adrenoreceptor antagonists].
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Alcian Blue; Animals; Anti-Asthmat | 2013 |
Cardioselective beta-blocker treatment of hypertension in patients with asthma: when do benefits outweigh risks?
Topics: Adrenergic beta-1 Receptor Antagonists; Asthma; Atenolol; Dose-Response Relationship, Drug; Humans; | 2012 |
Changes in beta 2-adrenoceptor and other signaling proteins produced by chronic administration of 'beta-blockers' in a murine asthma model.
Topics: Adrenergic beta-Antagonists; Airway Resistance; Animals; Asthma; Blotting, Western; Bronchial Provoc | 2008 |
[Administration of cardioselective beta-adrenoblockers in patients with arterial hypertension and/or ischemic heart disease associated with bronchoobstructive syndrome].
Topics: Adrenergic beta-Antagonists; Asthma; Benzopyrans; Comorbidity; Drug Administration Schedule; Ethanol | 2007 |
Effects of beta 1-adrenoceptor stimulation and blockade studied in asthmatic airways.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Asthma; Humans; Metoprolol; Practolol; Prenal | 1984 |
Ventilatory and haemodynamic effects of beta 1-selective and beta 2-selective stimulation in asthmatic patients.
Topics: Asthma; Blood Pressure; Heart Rate; Humans; Metoprolol; Practolol; Prenalterol; Receptors, Adrenergi | 1984 |
[Effective combined therapy of selective beta 1-adrenergic antagonist and selective beta 2-adrenergic agonist in a patient with bronchial asthma and hypertrophic cardiomyopathy].
Topics: Albuterol; Asthma; Cardiomyopathy, Hypertrophic; Drug Therapy, Combination; Female; Humans; Metoprol | 1984 |
The effect of cimetidine on the relative cardioselectivity of atenolol and metoprolol in asthmatic patients.
Topics: Asthma; Atenolol; Cimetidine; Double-Blind Method; Drug Interactions; Forced Expiratory Volume; Hear | 1984 |
The use of a selective beta-adrenergic receptor blocker for the preoperative preparation of thyrotoxic patients.
Topics: Adolescent; Aged; Asthma; Female; Heart Rate; Humans; Hyperthyroidism; Metoprolol; Preoperative Care | 1982 |
Ventilatory effects of metoprolol in asthmatic patients after administration of ordinary and slow-release tablets.
Topics: Asthma; Delayed-Action Preparations; Double-Blind Method; Forced Expiratory Volume; Humans; Metoprol | 1980 |
Persistent asthma after treatment with beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Aged; Asthma; Female; Humans; Male; Metoprolol; Middle Aged; Oxprenolol | 1979 |
Broncho-and cardioselective beta-receptor active drugs in the treatment of asthmatic patients. Clinical studies of effects and side effects of terbutaline, practolol and metoprolol.
Topics: Administration, Oral; Asthma; Bronchodilator Agents; Dose-Response Relationship, Drug; Drug Evaluati | 1977 |
Metoprolol tartrate for essential tremor.
Topics: Adult; Asthma; Humans; Male; Metoprolol; Propanolamines; Tremor | 1979 |
Comparison of the effect of the beta1-blocking drugs atenolol and metoprolol on bronchial asthma.
Topics: Adult; Aged; Asthma; Atenolol; Blood Pressure; Female; Heart Rate; Humans; Male; Metoprolol; Middle | 1978 |
Quantification of metoprolol beta 2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamic modelling.
Topics: Adult; Asthma; Female; Forced Expiratory Volume; Humans; Male; Metoprolol; Middle Aged; Potassium; T | 1992 |
Use of beta-blockade in a patient with phaeochromocytoma and asthma.
Topics: Adrenal Gland Neoplasms; Adult; Asthma; Female; Humans; Hypertension; Metoprolol; Pheochromocytoma; | 1992 |
Respiratory tolerance of bisoprolol and metoprolol in asthmatic patients.
Topics: Adrenergic beta-Antagonists; Asthma; Bisoprolol; Bronchial Spasm; Humans; Male; Metoprolol; Peak Exp | 1986 |
[Use of cardioselective adrenergic beta 1 receptor blockader spesicor in patients with ischemic heart disease associated with bronchial asthma].
Topics: Anti-Arrhythmia Agents; Asthma; Atrial Fibrillation; Cardiac Complexes, Premature; Coronary Disease; | 1987 |