Page last updated: 2024-10-31

metoprolol and Apnea, Obstructive Sleep

metoprolol has been researched along with Apnea, Obstructive Sleep in 5 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Research Excerpts

ExcerptRelevanceReference
" Here, we investigated the roles of metoprolol in regulation of atrial remodeling induced by chronic OSA."7.85Metoprolol prevents chronic obstructive sleep apnea-induced atrial fibrillation by inhibiting structural, sympathetic nervous and metabolic remodeling of the atria. ( Dong, X; Li, H; Li, M; Li, Y; Lu, S; Sun, L; Wang, X; Wang, Y; Yan, S; Yu, S; Zhao, J; Zhao, S, 2017)
"Metoprolol protects against chronic OSA-induced cardiac apoptosis and fibrosis in left ventricular myocytes of canines, which may provide new potential strategy for drug therapy of OSA."7.81Metoprolol Inhibits Cardiac Apoptosis and Fibrosis in a Canine Model of Chronic Obstructive Sleep Apnea. ( Ding, X; Li, H; Li, W; Li, Y; Liu, L; Liu, Z; Peng, W; Wang, D; Yan, S; Zhang, S; Zhao, J, 2015)
"Background Whether chronic obstructive sleep apnea ( OSA ) could promote epicardial adipose tissue ( EAT ) secretion of profibrotic adipokines, and thereby contribute to atrial fibrosis, and the potential therapeutic effects of metoprolol remain unknown."3.91Metoprolol Inhibits Profibrotic Remodeling of Epicardial Adipose Tissue in a Canine Model of Chronic Obstructive Sleep Apnea. ( Dai, H; Gong, Y; Han, Y; Li, T; Li, Y; Sheng, L; Sun, L; Xu, J; Yin, S; Yuan, Y; Zhang, Y, 2019)
" Here, we investigated the roles of metoprolol in regulation of atrial remodeling induced by chronic OSA."3.85Metoprolol prevents chronic obstructive sleep apnea-induced atrial fibrillation by inhibiting structural, sympathetic nervous and metabolic remodeling of the atria. ( Dong, X; Li, H; Li, M; Li, Y; Lu, S; Sun, L; Wang, X; Wang, Y; Yan, S; Yu, S; Zhao, J; Zhao, S, 2017)
"Metoprolol protects against chronic OSA-induced cardiac apoptosis and fibrosis in left ventricular myocytes of canines, which may provide new potential strategy for drug therapy of OSA."3.81Metoprolol Inhibits Cardiac Apoptosis and Fibrosis in a Canine Model of Chronic Obstructive Sleep Apnea. ( Ding, X; Li, H; Li, W; Li, Y; Liu, L; Liu, Z; Peng, W; Wang, D; Yan, S; Zhang, S; Zhao, J, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Yang, L1
Zhao, J3
Qu, Y1
Sun, Q1
Li, TT1
Yan, ML1
Duan, MJ1
Li, KX1
Wang, YR1
Huang, SY1
Zhang, S2
Li, Y5
Ai, J1
Sun, L2
Yan, S2
Wang, X1
Zhao, S1
Li, H2
Wang, Y1
Lu, S1
Dong, X1
Yu, S1
Li, M1
Shi, J1
Yuan, Y2
Deng, X1
Pan, Y1
He, M1
Liu, G1
Sun, D1
Wang, J1
Wang, W1
Dai, H1
Yin, S1
Zhang, Y1
Han, Y1
Li, T1
Xu, J1
Sheng, L1
Gong, Y1
Li, W1
Ding, X1
Wang, D2
Liu, L1
Peng, W1
Liu, Z1

Trials

1 trial available for metoprolol and Apnea, Obstructive Sleep

ArticleYear
Metoprolol has a similar therapeutic effect as amlodipine on BP lowering in hypertensive patients with obstructive sleep apnea.
    Sleep & breathing = Schlaf & Atmung, 2019, Volume: 23, Issue:1

    Topics: Administration, Oral; Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory

2019

Other Studies

4 other studies available for metoprolol and Apnea, Obstructive Sleep

ArticleYear
Metoprolol prevents neuronal dendrite remodeling in a canine model of chronic obstructive sleep apnea.
    Acta pharmacologica Sinica, 2020, Volume: 41, Issue:5

    Topics: Animals; Chronic Disease; Dendrites; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug;

2020
Metoprolol prevents chronic obstructive sleep apnea-induced atrial fibrillation by inhibiting structural, sympathetic nervous and metabolic remodeling of the atria.
    Scientific reports, 2017, 11-02, Volume: 7, Issue:1

    Topics: Adrenergic beta-1 Receptor Antagonists; AMP-Activated Protein Kinase Kinases; Animals; Atrial Fibril

2017
Metoprolol Inhibits Profibrotic Remodeling of Epicardial Adipose Tissue in a Canine Model of Chronic Obstructive Sleep Apnea.
    Journal of the American Heart Association, 2019, 02-05, Volume: 8, Issue:3

    Topics: Adipokines; Adipose Tissue; Animals; Cardiomyopathies; Chronic Disease; Disease Models, Animal; Dogs

2019
Metoprolol Inhibits Cardiac Apoptosis and Fibrosis in a Canine Model of Chronic Obstructive Sleep Apnea.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2015, Volume: 36, Issue:3

    Topics: Actins; Animals; Apoptosis; Apoptosis Inducing Factor; bcl-2-Associated X Protein; bcl-Associated De

2015