metoprolol has been researched along with Aortic Valve Insufficiency in 8 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the effects of metoprolol on cardiac function and myocyte calcium regulatory protein expressions in rabbits with heart failure." | 7.74 | [Effects of metoprolol on cardiac function and myocyte calcium regulatory protein expressions in rabbits with experimental heart failure]. ( Han, LH; Jiang, B; Jiang, TB; Jiang, WP; Li, BY; Li, HX; Liu, ZH; Song, JP; Yang, XJ; Zou, C, 2007) |
| "To investigate the effects of metoprolol on cardiac function and myocyte calcium regulatory protein expressions in rabbits with heart failure." | 3.74 | [Effects of metoprolol on cardiac function and myocyte calcium regulatory protein expressions in rabbits with experimental heart failure]. ( Han, LH; Jiang, B; Jiang, TB; Jiang, WP; Li, BY; Li, HX; Liu, ZH; Song, JP; Yang, XJ; Zou, C, 2007) |
| "Treatment with metoprolol of adults with chronic, moderate to severe AR had no effect on LV volumes." | 2.82 | Controlled release metoprolol for aortic regurgitation: a randomised clinical trial. ( Aakhus, S; Broch, K; Fosså, K; Gullestad, L; Hopp, E; Lønnebakken, MT; Massey, R; Stueflotten, W; Urheim, S, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Broch, K | 2 |
| Urheim, S | 2 |
| Lønnebakken, MT | 1 |
| Stueflotten, W | 2 |
| Massey, R | 2 |
| Fosså, K | 2 |
| Hopp, E | 2 |
| Aakhus, S | 2 |
| Gullestad, L | 2 |
| Evangelista, A | 1 |
| Otto, CM | 1 |
| Champetier, S | 2 |
| Bojmehrani, A | 1 |
| Beaudoin, J | 1 |
| Lachance, D | 3 |
| Plante, E | 3 |
| Roussel, E | 3 |
| Couet, J | 3 |
| Arsenault, M | 3 |
| Gaudreau, M | 1 |
| Drolet, MC | 2 |
| Zou, C | 1 |
| Liu, ZH | 1 |
| Jiang, B | 1 |
| Song, JP | 1 |
| Jiang, TB | 1 |
| Yang, XJ | 1 |
| Li, HX | 1 |
| Han, LH | 1 |
| Li, BY | 1 |
| Jiang, WP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Beta Blockade on Left Ventricular Remodeling and Function in Moderate to Severe Asymptomatic Aortic Regurgitation[NCT01157572] | Phase 4 | 75 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for metoprolol and Aortic Valve Insufficiency
| Article | Year |
|---|---|
Controlled release metoprolol for aortic regurgitation: a randomised clinical trial.
Topics: Adrenergic beta-1 Receptor Antagonists; Adult; Aortic Valve Insufficiency; Asymptomatic Diseases; De | 2016 |
7 other studies available for metoprolol and Aortic Valve Insufficiency
| Article | Year |
|---|---|
Medical treatment for chronic aortic regurgitation: β-blockers--maybe not bad, but good?
Topics: Adrenergic beta-1 Receptor Antagonists; Aortic Valve Insufficiency; Female; Humans; Male; Metoprolol | 2016 |
Heartbeat: Beta-blockers for aortic regurgitation.
Topics: Adrenergic beta-1 Receptor Antagonists; Aortic Valve Insufficiency; Female; Humans; Male; Metoprolol | 2016 |
Exercise capacity and peak oxygen consumption in asymptomatic patients with chronic aortic regurgitation.
Topics: Adolescent; Adrenergic beta-1 Receptor Antagonists; Adult; Aged; Aortic Valve Insufficiency; Asympto | 2016 |
Gene profiling of left ventricle eccentric hypertrophy in aortic regurgitation in rats: rationale for targeting the beta-adrenergic and renin-angiotensin systems.
Topics: Acute Disease; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorti | 2009 |
Effectiveness of beta-blockade in experimental chronic aortic regurgitation.
Topics: Adrenergic beta-Antagonists; Animals; Aortic Valve Insufficiency; Catecholamines; Cell Size; Chronic | 2004 |
[Effects of metoprolol on cardiac function and myocyte calcium regulatory protein expressions in rabbits with experimental heart failure].
Topics: Animals; Aortic Valve Insufficiency; Calcium; Calcium-Binding Proteins; Disease Models, Animal; Hear | 2007 |
Benefits of long-term beta-blockade in experimental chronic aortic regurgitation.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta | 2008 |