metoprolol has been researched along with Aortic Coarctation in 5 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Aortic Coarctation: A birth defect characterized by the narrowing of the AORTA that can be of varying degree and at any point from the transverse arch to the iliac bifurcation. Aortic coarctation causes arterial HYPERTENSION before the point of narrowing and arterial HYPOTENSION beyond the narrowed portion.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study addressed possible alterations in the pharmacodynamic and pharmacokinetic properties of the beta1-adrenoceptor antagonist metoprolol in experimental hypertension induced by abdominal aortic coarctation (ACo)." | 3.72 | Pharmacokinetic-pharmacodynamic properties of metoprolol in chronic aortic coarctated rats. ( Di Verniero, C; Höcht, C; Opezzo, JA; Taira, CA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moltzer, E | 1 |
| Mattace Raso, FU | 1 |
| Karamermer, Y | 1 |
| Boersma, E | 1 |
| Webb, GD | 1 |
| Simoons, ML | 1 |
| Danser, AH | 1 |
| van den Meiracker, AH | 1 |
| Roos-Hesselink, JW | 1 |
| Höcht, C | 4 |
| Di Verniero, C | 2 |
| Opezzo, JA | 4 |
| Taira, CA | 4 |
1 trial available for metoprolol and Aortic Coarctation
| Article | Year |
|---|---|
Comparison of Candesartan versus Metoprolol for treatment of systemic hypertension after repaired aortic coarctation.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II Type 1 Receptor Blockers; Aortic Coarctation; Ben | 2010 |
4 other studies available for metoprolol and Aortic Coarctation
| Article | Year |
|---|---|
In vivo and in vitro pharmacodynamic properties of metoprolol in aortic coarctated rats.
Topics: Animals; Aortic Coarctation; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Dru | 2003 |
Anterior hypothalamic beta-adrenergic activity in the maintenance of hypertension in aortic coarctated rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anterior Hypothalamic Nucleus; Aorti | 2004 |
Pharmacokinetic-pharmacodynamic properties of metoprolol in chronic aortic coarctated rats.
Topics: Animals; Aortic Coarctation; Blood Pressure; Bradycardia; Chronic Disease; Disease Models, Animal; D | 2004 |
Hypothalamic antihypertensive effect of metoprolol in chronic aortic coarctated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antihypertensive Agents; Aortic Coarctation; Female; Heart | 2005 |