metoprolol has been researched along with Angor Pectoris in 213 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
| Excerpt | Relevance | Reference |
|---|---|---|
| "One hundred and twelve beta-blockers-naive outpatients with stable angina pectoris were randomized to receive betaxolol, 20 mg once daily or metoprolol tartrate, 50 mg twice daily for 8 weeks." | 9.12 | Compliance, clinical outcome, and quality of life of patients with stable angina pectoris receiving once-daily betaxolol versus twice daily metoprolol: a randomized controlled trial. ( Kardas, P, 2007) |
| "To compare the analgesic effect of metoprolol and morphine in patients with chest pain due to suspected or definite acute myocardial infarction after initial treatment with intravenous metoprolol." | 9.09 | A comparison of metoprolol and morphine in the treatment of chest pain in patients with suspected acute myocardial infarction--the MEMO study. ( Abdon, NJ; Everts, B; Hedner, T; Herlitz, J; Karlson, B, 1999) |
| "The primary objective of this randomized, double-blind, parallel group trial was to compare the antianginal and antiischemic efficacy of a combination tablet of felodipine-metoprolol 10/100 mg once daily with both drugs given separately once daily in patients with stable effort-induced angina pectoris." | 9.09 | Antianginal efficacy of the combination of felodipine-metoprolol 10/100 mg compared with each drug alone in patients with stable effort-induced angina pectoris: a multicenter parallel group study. The TRAFFIC Study Group. ( Egstrup, K; Ellström, J; Emanuelsson, H; Forsby, M; Glud, T; Nikus, K; Pater, C; Scheibel, M; Tisell, A; Tötterman, KJ, 1999) |
| "To compare the effects of amlodipine and slow release metoprolol on subjective symptoms and signs of ischaemia during bicycle ergometric exercise tests in patients with stable angina pectoris." | 9.09 | Amlodipine versus slow release metoprolol in the treatment of stable exertional angina pectoris (AMSA). ( Midtbø, K; Mølstad, P, 2000) |
| " In a double-blind, crossover study, 28 patients with stable angina pectoris, proven coronary artery disease, and myocardial ischemia during Holter monitoring received metoprolol controlled-release 200 mg once daily and diltiazem 60 mg 4 times daily." | 9.08 | Usefulness of heart rate variability in predicting drug efficacy (metoprolol vs diltiazem) in patients with stable angina pectoris. ( Brouwer, J; Dijk, WA; Haaksma, J; Lie, KI; Man in 't Veld, AJ; Sijbring, P; van Veldhuisen, DJ; Viersma, JW, 1995) |
| "The effects of 1 month of treatment with either verapamil or metoprolol on several aspects of platelet function were studied at rest and during physical exercise or mental stress in patients with stable angina pectoris participating in the Angina Prognosis Study in Stockholm." | 9.08 | Platelet aggregability in vivo is attenuated by verapamil but not by metoprolol in patients with stable angina pectoris. ( Held, C; Hjemdahl, P; Rehnqvist, N; Wallén, NH, 1995) |
| "This study was designed to investigate whether combination therapy with metoprolol and nifedipine provides a greater anti-ischemic effect than does monotherapy in individual patients with stable angina pectoris." | 9.08 | Combination therapy with metoprolol and nifedipine versus monotherapy in patients with stable angina pectoris. Results of the International Multicenter Angina Exercise (IMAGE) Study. ( Ardissiono, D; Bae, EA; Egstrup, K; Marraccini, P; Merlini, PA; Omland, T; Rasmussen, K; Rehnqvist, N; Savonitto, S; Schjelderup-Mathiesen, PM; Wahlqvist, I, 1996) |
| "To study long-term treatment effects of metoprolol or verapamil on combined cardiovascular end points and psychological variables in patients with stable angina pectoris." | 9.08 | Effects of metoprolol vs verapamil in patients with stable angina pectoris. The Angina Prognosis Study in Stockholm (APSIS) ( Billing, E; Björkander, I; Eriksson, SV; Forslund, L; Held, C; Hjemdahl, P; Näsman, P; Rehnqvist, N; Wallén, NH, 1996) |
| "In the Angina Prognosis Study in Stockholm (APSIS), patients with stable angina pectoris were studied prospectively during double-blind treatment with metoprolol or verapamil." | 9.08 | Fibrinolytic variables and cardiovascular prognosis in patients with stable angina pectoris treated with verapamil or metoprolol. Results from the Angina Prognosis study in Stockholm. ( Björkander, I; Eriksson, SV; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N; Wallén, NH; Wiman, B, 1997) |
| " Out of 809 patients with stable angina pectoris, lipid variables were obtained in 786 patients at baseline, and after one month's double-blind treatment with metoprolol or verapamil, to evaluate treatment effects on these lipid variables." | 9.08 | Cardiovascular prognosis in relation to apolipoproteins and other lipid parameters in patients with stable angina pectoris treated with verapamil or metoprolol: results from the Angina Prognosis Study in Stockholm (APSIS). ( Angelin, B; Berglund, L; Björkander, I; Brodin, U; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N, 1997) |
| "The study aimed to compare the addition of felodipine to metoprolol, and of the replacement of metoprolol by felodipine, with continuation of metoprolol, in patients with angina pectoris despite optimal beta-blockade." | 9.08 | Addition of felodipine to metoprolol vs replacement of metoprolol by felodipine in patients with angina pectoris despite adequate beta-blockade. Results of the Felodipine ER and Metoprolol CR in Angina (FEMINA) Study. Working Group on Cardiovascular Resea ( Bernink, P; Bosma, A; Dunselman, P; Kragten, H; Liem, AH; Verdel, G, 1997) |
| "We compared the antianginal and antiischemic effect and tolerability of four different doses of felodipine extended-release (ER) tablets with placebo in patients with stable effort-induced angina pectoris treated with beta-blocker [metoprolol controlled release (CR) 100 mg once daily, o." | 9.07 | Felodipine versus placebo in stable effort-induced angina pectoris in patients inadequately controlled with metoprolol--a dose-finding study. ( Ahlström, P; Angman, K; Emanuelsson, H; Kujacic, V; Lundkvist, L; Rosenqvist, U; Tisell, A, 1994) |
| " Their antianginal efficacy was also compared in 23 patients with stable angina pectoris who were already on metoprolol." | 9.07 | Conventional and controlled release diltiazem. Bioavailability in healthy volunteers and anti-anginal effects in combination with metoprolol in stable angina pectoris. ( Arvill, A; Brorson, L; Fraser, T; Jörgensen, E; Larsson, H; Löfdahl, P; Olsson, AM; Olsson, SO, 1994) |
| "The antianginal activities of nicorandil, 10 and 20 mg bid, and metoprolol, 100 mg bid, were compared in patients with stable effort angina pectoris in a randomized, double-blind parallel group study lasting 7 weeks." | 9.07 | A double-blind comparison of nicorandil and metoprolol in stable effort angina pectoris. ( Bokor, D; Carotenuto, A; de Divitiis, M; de Divitiis, O; Di Somma, S; Liguori, V; Petitto, M, 1993) |
| " metoprolol in stable angina pectoris was compared in 114 patients recruited to a randomized double-blind cross-over study, consisting of a 4-week period on each drug." | 9.07 | Efficacy of epanolol versus metoprolol in angina pectoris: report from a Swedish multicentre study of exercise tolerance. ( Rydén, L, 1992) |
| "The effects of 5 and 10 mg of amlodipine and of placebo were compared in 21 patients with stable angina pectoris and multivessel coronary artery disease." | 9.07 | Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle. ( Julínek, J; Meluzín, J; Novák, M; Simek, P; Spinarová, L; Stejfa, M; Toman, J; Zeman, K, 1992) |
| "In order to evaluate the therapeutic effects of metoprolol, nifedipine, and their combination, 11 patients with secondary angina pectoris and with thallium tomographic findings indicating coronary artery disease were studied before and after these three treatment regimes in a single-blind cross-over study." | 9.06 | Hemodynamic effects of metoprolol and nifedipine in angina pectoris measured by isotope technique. ( Boström, PA, 1988) |
| "The mortality and morbidity were assessed during a 2-year follow-up in an acute intervention trial in suspected acute myocardial infarction with metoprolol (a selective beta 1-blocker)." | 9.06 | The influence of early intervention in acute myocardial infarction on long-term mortality and morbidity as assessed in the Göteborg metoprolol trial. ( Herlitz, J; Hjalmarson, A; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wilhelmsson, C, 1986) |
| "The orthostatic changes in heart rate (HR) and blood pressure (BP) were recorded in ten patients with stable angina pectoris before and after simultaneous sublingual nitroglycerin administration." | 9.05 | Orthostatic response before and after nitroglycerin in metoprolol- and verapamil-treated angina pectoris. ( Hyldstrup, L; Mogensen, NB; Nielsen, PE, 1983) |
| "The clinical efficacy of propranolol and metoprolol slow-release tablets (Durules) was compared in 20 patients with typical angina pectoris and concomitant hypertension." | 9.05 | Metoprolol in angina pectoris complicated by essential hypertension. A clinical comparison of the antianginal efficacy of metoprolol slow-release tablets (Durules) given once daily and propranolol tablets given twice daily. ( BLoem, TJ; Lindner, PC, 1981) |
| "Seventeen patients suffering from angina pectoris completed a double-blind trial comparing the efficacy and safety of metoprolol Durules administered once daily and metoprolol tablets administered twice daily both at a daily dosage of 200 mg." | 9.05 | Treatment of angina pectoris with metoprolol. A comparison between Durules administered once daily and tablets administered twice daily. ( Orö, L, 1981) |
| "The effects of 50, 100 and 200 mg oral single doses of metoprolol were compared in 23 patients with stable angina pectoris, previously treated with 50 mg metoprolol t." | 9.05 | A dose-response study on metoprolol in angina pectoris. ( Johnsson, G; Keyriläinen, O; Uusitalo, A, 1981) |
| "A clinical comparison of the sustained release form of metoprolol, consisting of a 200 mg metoprolol durule, with 100 mg conventional metoprolol twice daily, has been carried out to assess the therapeutic control of ten patients with stable angina pectoris." | 9.05 | A clinical evaluation of sustained release metoprolol durules in the treatment of angina pectoris. ( Besterman, EM; Comerford, MB, 1982) |
| "In a randomized controlled trial 31 patients, who were unsuccessfully being treated with metoprolol for severe angina pectoris, were also given molsidomine or placebo." | 9.05 | Combination of metoprolol with molsidomine in the treatment of angina pectoris. ( Lie, KI; Matroos, AW; van Mantgem, JP, 1985) |
| "The effects of metoprolol treatment in patients surviving acute myocardial infarction have been investigated in a double-blind randomized study." | 9.05 | Long-term treatment with metoprolol after myocardial infarction: effect on 3 year mortality and morbidity. ( Erhardt, L; Lundman, T; Olsson, G; Rehnqvist, N; Sjögren, A, 1985) |
| " The basis of this assumption was examined in a rest and exercise hemodynamic study of the effects of verapamil and the cardioselective beta-blocking drug, metoprolol, in 22 patients with stable angina pectoris and angiographically confirmed coronary artery disease." | 9.05 | The effects on left ventricular performance of verapamil and metoprolol singly and together in exercise-induced angina pectoris. ( Forsyth, D; Frais, MA; Hussain, M; Nelson, GI; Silke, B; Taylor, SH; Verma, SP, 1985) |
| "Following an initial dose response study, metoprolol, a selective beta1-receptor blocking agent, was compared with equipotent dosages of propanolol in a double blind cross-over study, including exercise tolerance tests, on fourteen patients with angina pectoris." | 9.04 | An eighteen months' study of the clinical response to metoprolol, a selective beta1-receptor blocking agent, in patients with angina pectoris. ( Besterman, EM; Comerford, MB, 1976) |
| "Three beta1-selective beta-blocker (metoprolol, practolol and H 87/07) were compared in 29 patients with stable angina pectoris." | 9.04 | A comparative study of three beta 1-adrenoreceptor blocking drugs with different degree of intrinsic stimulating activity (metoprolol, practolol and H 87/07) in patients with angina pectoris. ( Keyriläinen, O; Uusitalo, A, 1978) |
| "The effect of metoprolol in ECG experiments induced by a treadmill exercise test, was studied in 30 patients with stable angina pectoris." | 9.04 | [Metoprolol effect on ECG exercise test in patients with stable angina pectoris. Computer analysis (author's transl)]. ( Bruno, G; Burani, F; Dei Cas, L; Manca, C; Percoco, G; Scarfò, S, 1979) |
| "The effect on the exercise tolerance induced by a new selective beta1-receptor antagonist, metoprolol, given by a single administration per os, has been evaluated in 16 patients with stable angina pectoris." | 9.04 | [Effect of metoprolol on the exercise tolerance in patients with stable angina pectoris (author's transl)]. ( Giusti, C; Mosti, G; Tomei, G; Veltri, M, 1978) |
| "The effectiveness of metoprolol in relieving angina pectoris was compared with that of propranolol at equipotent dosages in a series of 20 patients." | 9.04 | Double-blind titrated-dose comparison of metoprolol and propranolol in the treatment of angina pectoris. ( Frick, MH; Luurila, O, 1976) |
| "Ten patients with typical angina pectoris and without hypertension, congestive heart failure or other disease were treated with alternating four-week courses of metoprolol (alpha beta1 cardioselective beta-blocking agent), propranolol and placebo." | 9.04 | Assessment of metoprolol, a cardioselective beta-blocking agent, during chronic therapy in patients with angina pectoris. ( Borer, JS; Comerford, MB; Sowton, E, 1976) |
| " A patient suffering from coronary artery disease and taking metoprolol and aspirin was stung by wasps and developed cutaneous allergic signs including rash, urticaria and orbital oedema." | 7.74 | Hymenoptera sting-induced Kounis syndrome: effects of aspirin and beta-blocker administration. ( Ioannidis, TI; Karpeta, MZ; Kounis, GN; Kounis, NG; Mazarakis, A; Notaras, SP; Rallis, DG; Tsintoni, AC, 2007) |
| "To compare efficacy and safety of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease (IHD) combined with type 2 diabetes." | 7.72 | [Clinical and metabolic effects of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease associated with type 2 diabetes]. ( Akhmedova, OO; Buval'tsev, VI; Gavrilov, IuV; Makolkin, VI; Petriĭ, VV, 2003) |
| "In 30 hypertensives with angina pectoris the acute action of beta-blockers Celiprolol and Metoprolol on the global and coronary haemodynamics was tested within cardiac catheter diagnostics." | 7.68 | [Acute changes of coronary and global hemodynamics in patients with angina pectoris and arterial hypertension caused by celiprolol and metoprolol]. ( Bruch, L; Franz, N; Gola, G; Heublein, B; Linss, G; Modersohn, D; Walde, T, 1990) |
| " The haemodynamic effects of sublingual nifedipine (20 mg) and intravenous metoprolol (10 mg) singly and in combination were therefore studied in 20 patients with severe angina pectoris associated with angiographically documented coronary artery disease." | 7.67 | The effect on left ventricular performance of nifedipine and metoprolol singly and together in exercise-induced angina pectoris. ( Ahuja, RC; Forsyth, D; Hussain, M; Nelson, GI; Silke, B; Taylor, SH, 1984) |
| "The cardioselective beta adrenoceptor blocking agent metoprolol was compared with the calcium antagonist verapamil in relation to effects on angina pectoris." | 7.66 | Comparison of metoprolol and verapamil in the treatment of angina pectoris. ( Arnman, K; Rydén, L, 1982) |
| " Carvedilol low dose/high dose was shown to be at least as safe and well tolerated as metoprolol low dose/high dose both in younger and elderly patients." | 6.69 | Comparison of safety and efficacy of carvedilol and metoprolol in stable angina pectoris. ( Griffiths, M; Hauf-Zachariou, U; Holtbrügge, W; König, S; Lahiri, A; Pfarr, E; van der Does, R, 1999) |
| "Nifedipine was administered to 20 patients (8 in group 1, and 12 in group 2)." | 6.67 | Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol. ( Andersen, PE; Egstrup, K, 1993) |
| "Nifedipine was ineffective, particularly in patients with angina predominantly on effort and with a moderate to severe reduction in exercise tolerance." | 6.67 | Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine. ( Ardissino, D; Egstrup, K; Feruglio, GA; Giordano, MP; Marraccini, P; Roncarolo, P; Rosenfeld, M; Savonitto, S; Slavich, G; Wahlqvist, I, 1991) |
| "Diltiazem was found to be effective in 74% of the patients with exertional angina, whereas metoprolol was beneficial in 62%." | 6.67 | [Comparison of antianginal effects of diltiazem and metoprolol in patients with ischemic heart disease with different clinical forms of angina pectoris]. ( Guliev, AB; Iaroshevskaia, FM; Krutovskikh, IV; Lupanov, VP; Sidorenko, BA, 1990) |
| "The diltiazem plasma levels were in the therapeutic range; metoprolol plasma levels, in contrast, were all below the therapeutic range." | 6.66 | Sustained-release diltiazem versus metoprolol in stable angina pectoris. ( Lie, KI; Posma, JL; van Dijk, RB, 1989) |
| "Treatment with metoprolol (100 mg twice daily), nifedipine (10 mg 3 times daily) and both drugs combined were compared for effect on clinical variables, bicycle ergometer exercise tolerance and adverse effects in a randomized double-blind, crossover study in patients with stable effort angina (n = 62)." | 6.66 | Metoprolol, nifedipine, and the combination in stable effort angina pectoris. ( Arstila, M; Bae, EA; Härkönen, R; Keyriläinen, O; Rytkönen, U; Schjelderup-Mathiesen, PM; Uusitalo, A; Wendelin, H, 1986) |
| "Metoprolol is a beta1-selective adrenoceptor blocking drug." | 6.36 | Metoprolol: a review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1977) |
| "Takotsubo syndrome, also called apical ballooning syndrome, is a clinical entity characterized by transient hypokinesis, akinesis, or dyskinesis of the left ventricular mid-segments with or without apical involvement, and without obstructive coronary lesions." | 5.36 | Haemodynamic effects of acute intravenous metoprolol in apical ballooning syndrome with dynamic left ventricular outflow tract obstruction. ( Bilato, C; Iliceto, S; Isabella, G; Migliore, F; Tarantini, G, 2010) |
| "In routine clinical practice in the management of angina (with or without coexisting hypertension), S-metoprolol administered at half the dose of the racemate, shows similar efficacy, safety and a trend towards a higher response rate." | 5.12 | Comparative clinical study of the efficacy and safety of a S-metoprolol ER tablet versus a racemate metoprolol ER tablet in patients with chronic stable angina. ( Aneja, P; Biswas, AD; Srinivas, A, 2007) |
| "One hundred and twelve beta-blockers-naive outpatients with stable angina pectoris were randomized to receive betaxolol, 20 mg once daily or metoprolol tartrate, 50 mg twice daily for 8 weeks." | 5.12 | Compliance, clinical outcome, and quality of life of patients with stable angina pectoris receiving once-daily betaxolol versus twice daily metoprolol: a randomized controlled trial. ( Kardas, P, 2007) |
| "To compare the analgesic effect of metoprolol and morphine in patients with chest pain due to suspected or definite acute myocardial infarction after initial treatment with intravenous metoprolol." | 5.09 | A comparison of metoprolol and morphine in the treatment of chest pain in patients with suspected acute myocardial infarction--the MEMO study. ( Abdon, NJ; Everts, B; Hedner, T; Herlitz, J; Karlson, B, 1999) |
| "The primary objective of this randomized, double-blind, parallel group trial was to compare the antianginal and antiischemic efficacy of a combination tablet of felodipine-metoprolol 10/100 mg once daily with both drugs given separately once daily in patients with stable effort-induced angina pectoris." | 5.09 | Antianginal efficacy of the combination of felodipine-metoprolol 10/100 mg compared with each drug alone in patients with stable effort-induced angina pectoris: a multicenter parallel group study. The TRAFFIC Study Group. ( Egstrup, K; Ellström, J; Emanuelsson, H; Forsby, M; Glud, T; Nikus, K; Pater, C; Scheibel, M; Tisell, A; Tötterman, KJ, 1999) |
| "The prognostic significance of ambulatory ischemia, alone and in relation to ischemia during exercise was assessed in 686 patients (475 men) with chronic stable angina pectoris taking part in the Angina Prognosis Study In Stockholm (APSIS), who had 24-hour ambulatory electrocardiographic registrations and exercise tests at baseline (n = 678) and after 1 month (n = 607) of double-blind treatment with metoprolol or verapamil." | 5.09 | Prognostic implications of ambulatory myocardial ischemia and arrhythmias and relations to ischemia on exercise in chronic stable angina pectoris (the Angina Prognosis Study in Stockholm [APSIS]). ( Björkander, I; Eriksson, SV; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N, 1999) |
| "In the Angina Prognosis Study in Stockholm (APSIS), 809 patients with stable angina pectoris were studied prospectively during double-blind treatment with verapamil or metoprolol." | 5.09 | Prognostic implications of intima-media thickness and plaques in the carotid and femoral arteries in patients with stable angina pectoris. ( Björkander, I; Eriksson, SV; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N, 2001) |
| "To compare the effects of amlodipine and slow release metoprolol on subjective symptoms and signs of ischaemia during bicycle ergometric exercise tests in patients with stable angina pectoris." | 5.09 | Amlodipine versus slow release metoprolol in the treatment of stable exertional angina pectoris (AMSA). ( Midtbø, K; Mølstad, P, 2000) |
| " In a double-blind, crossover study, 28 patients with stable angina pectoris, proven coronary artery disease, and myocardial ischemia during Holter monitoring received metoprolol controlled-release 200 mg once daily and diltiazem 60 mg 4 times daily." | 5.08 | Usefulness of heart rate variability in predicting drug efficacy (metoprolol vs diltiazem) in patients with stable angina pectoris. ( Brouwer, J; Dijk, WA; Haaksma, J; Lie, KI; Man in 't Veld, AJ; Sijbring, P; van Veldhuisen, DJ; Viersma, JW, 1995) |
| "The present study was designed to investigate which characteristics of anginal symptoms or exercise test results could predict the favorable anti-ischemic effect of the beta-adrenergic blocking agent metoprolol and the calcium antagonist nifedipine in patients with stable angina pectoris." | 5.08 | Selection of medical treatment in stable angina pectoris: results of the International Multicenter Angina Exercise (IMAGE) Study. ( Ardissino, D; Bae, EA; Egstrup, K; Marraccini, P; Merlini, PA; Omland, T; Rasmussen, K; Savonitto, S; Schjelderup-Mathiesen, PM; Wahlqvist, I, 1995) |
| "The effects of 1 month of treatment with either verapamil or metoprolol on several aspects of platelet function were studied at rest and during physical exercise or mental stress in patients with stable angina pectoris participating in the Angina Prognosis Study in Stockholm." | 5.08 | Platelet aggregability in vivo is attenuated by verapamil but not by metoprolol in patients with stable angina pectoris. ( Held, C; Hjemdahl, P; Rehnqvist, N; Wallén, NH, 1995) |
| "This study was conducted to determine whether rebound ischemia occurs during nitrate-free periods with intermittent cutaneous nitroglycerin therapy in patients with angina pectoris who are receiving background antianginal therapy." | 5.08 | Intermittent transdermal nitrates do not improve ischemia in patients taking beta-blockers or calcium antagonists: potential role of rebound ischemia during the nitrate-free period. ( Daxini, BV; Freedman, SB; Kelly, DT; Noyce, D, 1995) |
| "This study was designed to investigate whether combination therapy with metoprolol and nifedipine provides a greater anti-ischemic effect than does monotherapy in individual patients with stable angina pectoris." | 5.08 | Combination therapy with metoprolol and nifedipine versus monotherapy in patients with stable angina pectoris. Results of the International Multicenter Angina Exercise (IMAGE) Study. ( Ardissiono, D; Bae, EA; Egstrup, K; Marraccini, P; Merlini, PA; Omland, T; Rasmussen, K; Rehnqvist, N; Savonitto, S; Schjelderup-Mathiesen, PM; Wahlqvist, I, 1996) |
| "To study long-term treatment effects of metoprolol or verapamil on combined cardiovascular end points and psychological variables in patients with stable angina pectoris." | 5.08 | Effects of metoprolol vs verapamil in patients with stable angina pectoris. The Angina Prognosis Study in Stockholm (APSIS) ( Billing, E; Björkander, I; Eriksson, SV; Forslund, L; Held, C; Hjemdahl, P; Näsman, P; Rehnqvist, N; Wallén, NH, 1996) |
| "In the Angina Prognosis Study in Stockholm (APSIS), patients with stable angina pectoris were studied prospectively during double-blind treatment with metoprolol or verapamil." | 5.08 | Fibrinolytic variables and cardiovascular prognosis in patients with stable angina pectoris treated with verapamil or metoprolol. Results from the Angina Prognosis study in Stockholm. ( Björkander, I; Eriksson, SV; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N; Wallén, NH; Wiman, B, 1997) |
| " Out of 809 patients with stable angina pectoris, lipid variables were obtained in 786 patients at baseline, and after one month's double-blind treatment with metoprolol or verapamil, to evaluate treatment effects on these lipid variables." | 5.08 | Cardiovascular prognosis in relation to apolipoproteins and other lipid parameters in patients with stable angina pectoris treated with verapamil or metoprolol: results from the Angina Prognosis Study in Stockholm (APSIS). ( Angelin, B; Berglund, L; Björkander, I; Brodin, U; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N, 1997) |
| "The study aimed to compare the addition of felodipine to metoprolol, and of the replacement of metoprolol by felodipine, with continuation of metoprolol, in patients with angina pectoris despite optimal beta-blockade." | 5.08 | Addition of felodipine to metoprolol vs replacement of metoprolol by felodipine in patients with angina pectoris despite adequate beta-blockade. Results of the Felodipine ER and Metoprolol CR in Angina (FEMINA) Study. Working Group on Cardiovascular Resea ( Bernink, P; Bosma, A; Dunselman, P; Kragten, H; Liem, AH; Verdel, G, 1997) |
| "We compared the antianginal and antiischemic effect and tolerability of four different doses of felodipine extended-release (ER) tablets with placebo in patients with stable effort-induced angina pectoris treated with beta-blocker [metoprolol controlled release (CR) 100 mg once daily, o." | 5.07 | Felodipine versus placebo in stable effort-induced angina pectoris in patients inadequately controlled with metoprolol--a dose-finding study. ( Ahlström, P; Angman, K; Emanuelsson, H; Kujacic, V; Lundkvist, L; Rosenqvist, U; Tisell, A, 1994) |
| " Their antianginal efficacy was also compared in 23 patients with stable angina pectoris who were already on metoprolol." | 5.07 | Conventional and controlled release diltiazem. Bioavailability in healthy volunteers and anti-anginal effects in combination with metoprolol in stable angina pectoris. ( Arvill, A; Brorson, L; Fraser, T; Jörgensen, E; Larsson, H; Löfdahl, P; Olsson, AM; Olsson, SO, 1994) |
| "We conducted a randomised controlled trial to study the effects of metoprolol and diltiazem on the total ischaemic burden--sum of symptomatic and silent myocardial ischaemia, in 146 patients with stable angina pectoris." | 5.07 | Effect of metoprolol and diltiazem on the total ischaemic burden in patients with chronic stable angina: a randomized controlled trial. ( Ahuja, RC; Kumar, RR; Saran, RK; Sinha, N, 1993) |
| "The antianginal activities of nicorandil, 10 and 20 mg bid, and metoprolol, 100 mg bid, were compared in patients with stable effort angina pectoris in a randomized, double-blind parallel group study lasting 7 weeks." | 5.07 | A double-blind comparison of nicorandil and metoprolol in stable effort angina pectoris. ( Bokor, D; Carotenuto, A; de Divitiis, M; de Divitiis, O; Di Somma, S; Liguori, V; Petitto, M, 1993) |
| " metoprolol in stable angina pectoris was compared in 114 patients recruited to a randomized double-blind cross-over study, consisting of a 4-week period on each drug." | 5.07 | Efficacy of epanolol versus metoprolol in angina pectoris: report from a Swedish multicentre study of exercise tolerance. ( Rydén, L, 1992) |
| "The effects of 5 and 10 mg of amlodipine and of placebo were compared in 21 patients with stable angina pectoris and multivessel coronary artery disease." | 5.07 | Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle. ( Julínek, J; Meluzín, J; Novák, M; Simek, P; Spinarová, L; Stejfa, M; Toman, J; Zeman, K, 1992) |
| "The use of metoprolol combined with nifedipine and diltiazem was studied and compared in 32 patients suffering from coronary disease associated with angina pectoris of effort." | 5.06 | [The use of metoprolol with calcium antagonists of different mechanisms of action (diltiazem and nifedipine) in patients with stenocardia of effort]. ( Guliev, AB; Lupanov, VP; Sidorenko, BA, 1990) |
| "From a large randomized multicentre trial of metoprolol in suspected acute myocardial infarction (n = 5778) we report on the outcome during 1 year of follow-up, in relation to early diagnosis." | 5.06 | Mortality and morbidity during one year of follow-up in suspected acute myocardial infarction in relation to early diagnosis: experiences from the MIAMI trial. ( Herlitz, J; Hjalmarson, A; Karlson, BW, 1990) |
| "In order to evaluate the therapeutic effects of metoprolol, nifedipine, and their combination, 11 patients with secondary angina pectoris and with thallium tomographic findings indicating coronary artery disease were studied before and after these three treatment regimes in a single-blind cross-over study." | 5.06 | Hemodynamic effects of metoprolol and nifedipine in angina pectoris measured by isotope technique. ( Boström, PA, 1988) |
| "Alinidine, a drug which reduces heart rate without depressing myocardial function was compared against metoprolol, a beta-blocking drug, in the treatment of stable angina pectoris in a double-blind cross-over trial." | 5.06 | ST 567 (alinidine) in stable angina: a comparison with metoprolol. ( Balakumaran, K; Bokslag, M; Fels, PW; Hugenholtz, PG; Jovanovic, A; Lubsen, J; van Es, GA, 1987) |
| "In a randomized, double-blind, cross-over study treatment with a new controlled-release (CR) preparation of metoprolol, given once daily, was compared with treatment with conventional metoprolol tablets, given twice daily, in 115 patients with stable effort angina pectoris." | 5.06 | The antianginal efficacy and tolerability of controlled-release metoprolol once daily: a comparison with conventional metoprolol tablets twice daily. ( Egstrup, K; Gundersen, T; Härkönen, R; Karlsson, E; Lundgren, B, 1988) |
| "The mortality and morbidity were assessed during a 2-year follow-up in an acute intervention trial in suspected acute myocardial infarction with metoprolol (a selective beta 1-blocker)." | 5.06 | The influence of early intervention in acute myocardial infarction on long-term mortality and morbidity as assessed in the Göteborg metoprolol trial. ( Herlitz, J; Hjalmarson, A; Swedberg, K; Vedin, A; Waagstein, F; Waldenström, A; Wilhelmsson, C, 1986) |
| "In order to evaluate the negative inotropic effects of sotalol, metoprolol, and propranolol in patients with chronic stable angina pectoris, left ventricular ejection fraction (LVEF) was measured with radionuclide angiography and echocardiography." | 5.05 | Beta-blocker therapy evaluated by radionuclide angiography: a study in chronic stable angina. ( Lessem, J, 1982) |
| "The orthostatic changes in heart rate (HR) and blood pressure (BP) were recorded in ten patients with stable angina pectoris before and after simultaneous sublingual nitroglycerin administration." | 5.05 | Orthostatic response before and after nitroglycerin in metoprolol- and verapamil-treated angina pectoris. ( Hyldstrup, L; Mogensen, NB; Nielsen, PE, 1983) |
| "The clinical efficacy of propranolol and metoprolol slow-release tablets (Durules) was compared in 20 patients with typical angina pectoris and concomitant hypertension." | 5.05 | Metoprolol in angina pectoris complicated by essential hypertension. A clinical comparison of the antianginal efficacy of metoprolol slow-release tablets (Durules) given once daily and propranolol tablets given twice daily. ( BLoem, TJ; Lindner, PC, 1981) |
| "Seventeen patients suffering from angina pectoris completed a double-blind trial comparing the efficacy and safety of metoprolol Durules administered once daily and metoprolol tablets administered twice daily both at a daily dosage of 200 mg." | 5.05 | Treatment of angina pectoris with metoprolol. A comparison between Durules administered once daily and tablets administered twice daily. ( Orö, L, 1981) |
| "The effect of isosorbide-dinitrate (ISDN) 20 mg 4 times daily against placebo has been tested in 12 patients with stable effort induced angina pectoris receiving prophylactic treatment with metoprolol." | 5.05 | Haemodynamic and clinical effects of isosorbide-dinitrate in patients with severe effort angina on beta-blocking treatment. ( Hesse, B; Jensen, G; Rasmussen, S; Trautner, F, 1983) |
| "The effects of 50, 100 and 200 mg oral single doses of metoprolol were compared in 23 patients with stable angina pectoris, previously treated with 50 mg metoprolol t." | 5.05 | A dose-response study on metoprolol in angina pectoris. ( Johnsson, G; Keyriläinen, O; Uusitalo, A, 1981) |
| "A clinical comparison of the sustained release form of metoprolol, consisting of a 200 mg metoprolol durule, with 100 mg conventional metoprolol twice daily, has been carried out to assess the therapeutic control of ten patients with stable angina pectoris." | 5.05 | A clinical evaluation of sustained release metoprolol durules in the treatment of angina pectoris. ( Besterman, EM; Comerford, MB, 1982) |
| "To assess the duration of improved exercise tolerance by metoprolol given in a new sustained-release formulation, 40 in-patients affected by stable exercise-induced angina pectoris received single-blind placebo in day 1 and thereafter, in double-blind cross-over once daily administration, metoprolol RETARD 100 mg and 200 mg in days 3 and 5." | 5.05 | [Exercise tolerance in angina patients 3 and 24 hours after administration of a new delayed-action preparation of metoprolol]. ( Bongini, AM; Cordoni, M; Giusti, C; Pentimone, F; Regoli, F; Verdecchia, P, 1981) |
| "In a randomized controlled trial 31 patients, who were unsuccessfully being treated with metoprolol for severe angina pectoris, were also given molsidomine or placebo." | 5.05 | Combination of metoprolol with molsidomine in the treatment of angina pectoris. ( Lie, KI; Matroos, AW; van Mantgem, JP, 1985) |
| "The effects of metoprolol treatment in patients surviving acute myocardial infarction have been investigated in a double-blind randomized study." | 5.05 | Long-term treatment with metoprolol after myocardial infarction: effect on 3 year mortality and morbidity. ( Erhardt, L; Lundman, T; Olsson, G; Rehnqvist, N; Sjögren, A, 1985) |
| " The basis of this assumption was examined in a rest and exercise hemodynamic study of the effects of verapamil and the cardioselective beta-blocking drug, metoprolol, in 22 patients with stable angina pectoris and angiographically confirmed coronary artery disease." | 5.05 | The effects on left ventricular performance of verapamil and metoprolol singly and together in exercise-induced angina pectoris. ( Forsyth, D; Frais, MA; Hussain, M; Nelson, GI; Silke, B; Taylor, SH; Verma, SP, 1985) |
| "Following an initial dose response study, metoprolol, a selective beta1-receptor blocking agent, was compared with equipotent dosages of propanolol in a double blind cross-over study, including exercise tolerance tests, on fourteen patients with angina pectoris." | 5.04 | An eighteen months' study of the clinical response to metoprolol, a selective beta1-receptor blocking agent, in patients with angina pectoris. ( Besterman, EM; Comerford, MB, 1976) |
| "Three beta1-selective beta-blocker (metoprolol, practolol and H 87/07) were compared in 29 patients with stable angina pectoris." | 5.04 | A comparative study of three beta 1-adrenoreceptor blocking drugs with different degree of intrinsic stimulating activity (metoprolol, practolol and H 87/07) in patients with angina pectoris. ( Keyriläinen, O; Uusitalo, A, 1978) |
| "The effect of metoprolol in ECG experiments induced by a treadmill exercise test, was studied in 30 patients with stable angina pectoris." | 5.04 | [Metoprolol effect on ECG exercise test in patients with stable angina pectoris. Computer analysis (author's transl)]. ( Bruno, G; Burani, F; Dei Cas, L; Manca, C; Percoco, G; Scarfò, S, 1979) |
| "The effect on the exercise tolerance induced by a new selective beta1-receptor antagonist, metoprolol, given by a single administration per os, has been evaluated in 16 patients with stable angina pectoris." | 5.04 | [Effect of metoprolol on the exercise tolerance in patients with stable angina pectoris (author's transl)]. ( Giusti, C; Mosti, G; Tomei, G; Veltri, M, 1978) |
| "3 years, with stable angina pectoris earlier treated with beta-blockers, were investigated with standardized exercise tests to evaluate the action of nifedipine alone and in combination with a beta-blocker." | 5.04 | Antianginal efficiency of nifedipine with and without a beta-blocker, studied with exercise test. A double-blind, randomized subacute study. ( Ekelund, LG; Orö, L, 1979) |
| "The effectiveness of metoprolol in relieving angina pectoris was compared with that of propranolol at equipotent dosages in a series of 20 patients." | 5.04 | Double-blind titrated-dose comparison of metoprolol and propranolol in the treatment of angina pectoris. ( Frick, MH; Luurila, O, 1976) |
| "Ten patients with typical angina pectoris and without hypertension, congestive heart failure or other disease were treated with alternating four-week courses of metoprolol (alpha beta1 cardioselective beta-blocking agent), propranolol and placebo." | 5.04 | Assessment of metoprolol, a cardioselective beta-blocking agent, during chronic therapy in patients with angina pectoris. ( Borer, JS; Comerford, MB; Sowton, E, 1976) |
| " A patient suffering from coronary artery disease and taking metoprolol and aspirin was stung by wasps and developed cutaneous allergic signs including rash, urticaria and orbital oedema." | 3.74 | Hymenoptera sting-induced Kounis syndrome: effects of aspirin and beta-blocker administration. ( Ioannidis, TI; Karpeta, MZ; Kounis, GN; Kounis, NG; Mazarakis, A; Notaras, SP; Rallis, DG; Tsintoni, AC, 2007) |
| "In a prospective study of 809 patients with stable angina pectoris randomized to receive metoprolol or verapamil, a subgroup of 69 diabetic patients was compared with non-diabetic patients with respect to the risk of cardiovascular (CV) death, non-fatal myocardial infarction (MI) and revascularization." | 3.73 | The impact of diabetes or elevated fasting blood glucose on cardiovascular prognosis in patients with stable angina pectoris. ( Björkander, I; Forslund, L; Held, C; Hjemdahl, P; Rehnqvist, N, 2005) |
| "To compare efficacy and safety of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease (IHD) combined with type 2 diabetes." | 3.72 | [Clinical and metabolic effects of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease associated with type 2 diabetes]. ( Akhmedova, OO; Buval'tsev, VI; Gavrilov, IuV; Makolkin, VI; Petriĭ, VV, 2003) |
| "In 759 patients with acute myocardial infarction in whom serum activity of heat stable lactate dehydrogenase had been determined every 12 hours for 108 hours after randomisation in an early intervention trial with metoprolol." | 3.69 | Ten year mortality in relation to original size of myocardial infarct: results from the Gothenburg metoprolol study. ( Herlitz, J; Hjalmarson, A; Karlson, BW, 1994) |
| "In 30 hypertensives with angina pectoris the acute action of beta-blockers Celiprolol and Metoprolol on the global and coronary haemodynamics was tested within cardiac catheter diagnostics." | 3.68 | [Acute changes of coronary and global hemodynamics in patients with angina pectoris and arterial hypertension caused by celiprolol and metoprolol]. ( Bruch, L; Franz, N; Gola, G; Heublein, B; Linss, G; Modersohn, D; Walde, T, 1990) |
| " The haemodynamic effects of sublingual nifedipine (20 mg) and intravenous metoprolol (10 mg) singly and in combination were therefore studied in 20 patients with severe angina pectoris associated with angiographically documented coronary artery disease." | 3.67 | The effect on left ventricular performance of nifedipine and metoprolol singly and together in exercise-induced angina pectoris. ( Ahuja, RC; Forsyth, D; Hussain, M; Nelson, GI; Silke, B; Taylor, SH, 1984) |
| "Ten male patients suffering from stable angina pectoris were studied at rest and immediately after exercise during treatment either with timolol (a non-selective beta-blocker) or with metoprolol (a beta 1-selective blocker)." | 3.67 | Differential effects of timolol and metoprolol on platelet function at rest and during exercise. ( Eldrup, E; Jørgensen, EO; Knudsen, JB; Winther, K, 1988) |
| "The cardioselective beta adrenoceptor blocking agent metoprolol was compared with the calcium antagonist verapamil in relation to effects on angina pectoris." | 3.66 | Comparison of metoprolol and verapamil in the treatment of angina pectoris. ( Arnman, K; Rydén, L, 1982) |
| " We administered 40-, 80- and 120-mg doses of verapamil orally to 15 patients with angina pectoris who were receiving high doses of propranolol or metoprolol." | 3.66 | Hemodynamic consequences of combined beta-adrenergic and slow calcium channel blockade in man. ( Gorlin, R; Guererro, J; Holt, J; McAllister, RG; Medina, N; Meller, J; Packer, M; Smith, H; Todd, GD; Yushak, M, 1982) |
| " Thirty-six subjects (healthy, severe angina pectoris, or acute myocardial infarction) were studied 15 minutes either after the beta 1-selective beta-blocking drug metoprolol had been administered in total doses of 2 and 10 mg intravenously or after pindolol, a beta blocker with intrinsic sympathomimetic activity (ISA), in total doses of 0." | 3.66 | Cardiac safety of acute beta blockade: intrinsic sympathomimetic activity is superior to beta-1 selectivity. ( Heikkilä, J; Nieminen, MS, 1982) |
| "Aim of this study was to assess clinical and pharmacoeconomic effects of long term use of adrenoblockers in patients with ischemic heart disease (IHD) undergoing coronary artery bypass grafting." | 2.75 | [Clinical-pharmacoeconomical aspects of ß-adrenoblockers use in patients with ischemic heart disease undergoing coronary artery bypass grafting]. ( Dronova, EP; Lopatin, IuM, 2010) |
| "Fatigue, but not breathlessness, remained a significant predictor for developing worsening heart failure (RR 1." | 2.71 | Symptoms in patients with heart failure are prognostic predictors: insights from COMET. ( Charlesworth, A; Cleland, JG; Ekman, I; Metra, M; Poole-Wilson, PA; Swedberg, K, 2005) |
| " Carvedilol low dose/high dose was shown to be at least as safe and well tolerated as metoprolol low dose/high dose both in younger and elderly patients." | 2.69 | Comparison of safety and efficacy of carvedilol and metoprolol in stable angina pectoris. ( Griffiths, M; Hauf-Zachariou, U; Holtbrügge, W; König, S; Lahiri, A; Pfarr, E; van der Does, R, 1999) |
| "Fibrinogen and WBC were independent predictors of CV death or non-fatal MI as well as disease progression leading to revascularization in patients with stable angina pectoris." | 2.69 | Inflammatory and hemostatic markers in relation to cardiovascular prognosis in patients with stable angina pectoris. Results from the APSIS study. The Angina Prognosis Study in Stockholm. ( Björkander, I; Forslund, L; Håkan Wallén, N; Held, C; Hjemdahl, P; Rehnqvist, N; Wiman, B, 2000) |
| "Atropine was given to patients on beta-blockers more often [(22/26) vs (6/26)] than to those off beta-blockers (P < 0." | 2.67 | Atropine increases the accuracy of dobutamine stress echocardiography in patients taking beta-blockers. ( Bellotti, P; Boersma, E; el-Said, ES; Fioretti, PM; Forster, T; McNeill, AJ; Poldermans, D; Roelandt, JR; Salustri, A, 1994) |
| "Nifedipine was administered to 20 patients (8 in group 1, and 12 in group 2)." | 2.67 | Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol. ( Andersen, PE; Egstrup, K, 1993) |
| "Nifedipine was ineffective, particularly in patients with angina predominantly on effort and with a moderate to severe reduction in exercise tolerance." | 2.67 | Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine. ( Ardissino, D; Egstrup, K; Feruglio, GA; Giordano, MP; Marraccini, P; Roncarolo, P; Rosenfeld, M; Savonitto, S; Slavich, G; Wahlqvist, I, 1991) |
| "Diltiazem was found to be effective in 74% of the patients with exertional angina, whereas metoprolol was beneficial in 62%." | 2.67 | [Comparison of antianginal effects of diltiazem and metoprolol in patients with ischemic heart disease with different clinical forms of angina pectoris]. ( Guliev, AB; Iaroshevskaia, FM; Krutovskikh, IV; Lupanov, VP; Sidorenko, BA, 1990) |
| "The diltiazem plasma levels were in the therapeutic range; metoprolol plasma levels, in contrast, were all below the therapeutic range." | 2.66 | Sustained-release diltiazem versus metoprolol in stable angina pectoris. ( Lie, KI; Posma, JL; van Dijk, RB, 1989) |
| "Celiprolol is a cardioselective beta-adrenoceptor antagonist with attributed cardiostimulant properties." | 2.66 | Comparative effects of metoprolol and celiprolol on cardiac hemodynamics and left ventricular volume at rest and during exercise-induced angina. ( Frais, MA; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1986) |
| "Treatment with metoprolol (100 mg twice daily), nifedipine (10 mg 3 times daily) and both drugs combined were compared for effect on clinical variables, bicycle ergometer exercise tolerance and adverse effects in a randomized double-blind, crossover study in patients with stable effort angina (n = 62)." | 2.66 | Metoprolol, nifedipine, and the combination in stable effort angina pectoris. ( Arstila, M; Bae, EA; Härkönen, R; Keyriläinen, O; Rytkönen, U; Schjelderup-Mathiesen, PM; Uusitalo, A; Wendelin, H, 1986) |
| "Nifedipine is a calcium antagonist with established anti-vasospastic action in man and, possibly cardioprotective effects during ischaemia." | 2.65 | Acute myocardial ischaemia: what information can be expected in the near future from ongoing clinical trials with nifedipine? ( Hugenholtz, PG; Lubsen, J, 1983) |
| " Acute dose-response studies showed that all five drugs improved exercise tolerance and reduced ST-segment depression, heart rate and blood pressure by a similar degree in comparison with a placebo (P less than 0." | 2.65 | Comparison of the immediate effects of five beta-adrenoreceptor-blocking drugs with different ancillary properties in angina pectoris. ( Davidson, C; Singleton, W; Taylor, SH; Thadani, U, 1979) |
| " If standard doses of beta-blockers are used in PM subjects, they may be susceptible to concentration-related adverse reactions and they may also require lower and less frequent dosing for control of angina pectoris." | 2.37 | Oxidation phenotype and the metabolism and action of beta-blockers. ( Lennard, MS, 1985) |
| "Amiodarone is an extremely potent drug which is effective for both supraventricular as well as ventricular arrhythmias." | 2.36 | New antiarrhythmic drugs. ( Hess, DS; Scheinman, MM, 1983) |
| "Metoprolol is a beta1-selective adrenoceptor blocking drug." | 2.36 | Metoprolol: a review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris. ( Avery, GS; Brogden, RN; Heel, RC; Speight, TM, 1977) |
| "Takotsubo syndrome, also called apical ballooning syndrome, is a clinical entity characterized by transient hypokinesis, akinesis, or dyskinesis of the left ventricular mid-segments with or without apical involvement, and without obstructive coronary lesions." | 1.36 | Haemodynamic effects of acute intravenous metoprolol in apical ballooning syndrome with dynamic left ventricular outflow tract obstruction. ( Bilato, C; Iliceto, S; Isabella, G; Migliore, F; Tarantini, G, 2010) |
| " However, as dosage adjustment and close observation may be necessary to minimise side effects, the use of this combination should be limited to hospital practice." | 1.27 | Tolerability of combined treatment with verapamil and beta-blockers in angina resistant to monotherapy. ( McGourty, JC; Silas, JH; Solomon, SA, 1985) |
| "Nifedipine is a potent coronary vasodilator in the resting state and an effective afterload-reducing agent." | 1.27 | Addition of nifedipine to maximal beta-blocker-nitrate therapy: effects on exercise capacity and global left ventricular performance at rest and during exercise. ( Antman, E; Ganz, P; Holman, BL; Koslowski, J; Nesto, RW; White, HD; Wynne, J, 1985) |
| "Nitroglycerin was well suited for treatment of acute attacks." | 1.26 | Prinzmetal's variant angina. ( Efsen, F; Sandøe, E; Vilhelmsen, R, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 121 (56.81) | 18.7374 |
| 1990's | 55 (25.82) | 18.2507 |
| 2000's | 27 (12.68) | 29.6817 |
| 2010's | 10 (4.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Qureshi, R | 1 |
| Kao, L | 1 |
| Gupta, RP | 1 |
| Fortmüller, U | 1 |
| Fi, Z | 1 |
| Szentes, V | 1 |
| Meena, DS | 1 |
| Meena, CB | 1 |
| Parvez, J | 1 |
| Weintraub, WS | 1 |
| Spertus, JA | 1 |
| Kolm, P | 1 |
| Maron, DJ | 1 |
| Zhang, Z | 1 |
| Jurkovitz, C | 1 |
| Zhang, W | 1 |
| Hartigan, PM | 1 |
| Lewis, C | 1 |
| Veledar, E | 1 |
| Bowen, J | 1 |
| Dunbar, SB | 1 |
| Deaton, C | 1 |
| Kaufman, S | 1 |
| O'Rourke, RA | 1 |
| Goeree, R | 1 |
| Barnett, PG | 1 |
| Teo, KK | 1 |
| Boden, WE | 1 |
| Mancini, GB | 1 |
| Bangalore, S | 1 |
| Gluud, C | 1 |
| Wetterslev, J | 1 |
| Messerli, FH | 1 |
| Björkander, I | 12 |
| Forslund, L | 14 |
| Ericson, M | 3 |
| Rehnqvist, N | 19 |
| Hjemdahl, P | 16 |
| Kahan, T | 3 |
| Kersemans, M | 1 |
| Van Heuverswyn, F | 1 |
| De Pauw, M | 1 |
| Gheeraert, P | 1 |
| Taeymans, Y | 1 |
| Drieghe, B | 1 |
| Arslan, S | 1 |
| Gurlertop, Y | 1 |
| Elbey, MA | 1 |
| Karakelleoglu, S | 1 |
| Migliore, F | 1 |
| Bilato, C | 1 |
| Isabella, G | 1 |
| Iliceto, S | 1 |
| Tarantini, G | 1 |
| Zedigh, C | 1 |
| Alho, A | 1 |
| Hammar, E | 1 |
| Karlsson, T | 2 |
| Kellerth, T | 1 |
| Svensson, L | 1 |
| Grimbrandt, E | 1 |
| Herlitz, J | 6 |
| Lopatin, IuM | 1 |
| Dronova, EP | 1 |
| Sengul, C | 1 |
| Fotbolcu, H | 1 |
| Ozde, K | 1 |
| Duman, D | 1 |
| Makolkin, VI | 1 |
| Akhmedova, OO | 1 |
| Buval'tsev, VI | 1 |
| Gavrilov, IuV | 1 |
| Petriĭ, VV | 1 |
| Ruzyllo, W | 1 |
| Szwed, H | 3 |
| Sadowski, Z | 2 |
| Elikowski, W | 2 |
| Grzelak-Szafranska, H | 1 |
| Orszulak, W | 2 |
| Szymczak, K | 2 |
| Winter, M | 2 |
| Ekman, I | 1 |
| Cleland, JG | 1 |
| Swedberg, K | 2 |
| Charlesworth, A | 1 |
| Metra, M | 1 |
| Poole-Wilson, PA | 1 |
| Eriksson, SV | 7 |
| Held, C | 13 |
| Näsman, P | 2 |
| Cocco, G | 1 |
| Chu, D | 1 |
| Dupliakov, DV | 1 |
| Glukhova, VL | 1 |
| Vozhdaeva, ZI | 1 |
| Golovina, GA | 1 |
| Ioannidis, TI | 1 |
| Mazarakis, A | 1 |
| Notaras, SP | 1 |
| Karpeta, MZ | 1 |
| Tsintoni, AC | 1 |
| Kounis, GN | 1 |
| Rallis, DG | 1 |
| Kounis, NG | 1 |
| Almquist, T | 1 |
| Aneja, P | 1 |
| Srinivas, A | 1 |
| Biswas, AD | 1 |
| Kardas, P | 1 |
| Thadani, U | 2 |
| Davidson, C | 2 |
| Singleton, W | 2 |
| Taylor, SH | 7 |
| Koch-Weser, J | 1 |
| Frishman, WH | 2 |
| Lessem, J | 1 |
| Segal, BL | 1 |
| Kotler, MN | 1 |
| Iskandrian, AS | 1 |
| Delius, W | 1 |
| Jackson, EA | 1 |
| Sullman, SA | 1 |
| Furberg, CD | 1 |
| Friedewald, WT | 1 |
| Robertson, NJ | 1 |
| Elenbaas, JK | 1 |
| Hamburger, S | 1 |
| Lubsen, J | 11 |
| Hugenholtz, PG | 4 |
| Sterndorff, B | 1 |
| Cioglia, G | 1 |
| Cherchi, A | 1 |
| Mercuro, G | 1 |
| Lai, C | 1 |
| Lai, O | 1 |
| Piras, S | 1 |
| Scheinman, MM | 1 |
| Hess, DS | 1 |
| Hyldstrup, L | 1 |
| Mogensen, NB | 1 |
| Nielsen, PE | 1 |
| Michels, R | 1 |
| Serruys, PW | 1 |
| Simoons, ML | 6 |
| Pfisterer, M | 2 |
| Fridrich, R | 1 |
| Burkart, F | 2 |
| Shanks, RG | 1 |
| Eisenberg, JN | 1 |
| Oakley, GD | 1 |
| Nelson, GI | 2 |
| Silke, B | 5 |
| Ahuja, RC | 2 |
| Hussain, M | 2 |
| Forsyth, D | 2 |
| Jensen, G | 2 |
| Trautner, F | 2 |
| Rasmussen, S | 2 |
| Hesse, B | 2 |
| Sandøe, E | 1 |
| Vilhelmsen, R | 1 |
| Efsen, F | 1 |
| Jones, DK | 1 |
| Solomon, S | 1 |
| Mosti, GB | 2 |
| Santoro, G | 2 |
| Galetta, F | 2 |
| Dalle Luche, A | 1 |
| Regoli, F | 2 |
| Giusti, C | 5 |
| BLoem, TJ | 1 |
| Lindner, PC | 1 |
| Orö, L | 2 |
| Arnman, K | 1 |
| Rydén, L | 3 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| CSP #424 - Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation[NCT00007657] | Phase 3 | 3,260 participants (Anticipated) | Interventional | 1998-12-31 | Completed | ||
| Quality of Life and Achievement of Target of Treatment After Optimized Medical Treatment, Physical Training and Smoking Cessation With or Without Percutaneous Coronary Intervention in Patients With Stable Angina Pectoris.[NCT00825604] | Phase 2 | 0 participants (Actual) | Interventional | 2009-01-31 | Withdrawn (stopped due to Because of poor inclusion difficulties to find patient) | ||
| Impact of Coronary Artery Stenting on Quantitative Myocardial Blood Flow and Health Status[NCT04475094] | 75 participants (Anticipated) | Observational | 2019-12-23 | Recruiting | |||
| Effects of a Mindfulness-Based Intervention on Symptoms and Signs, Well-Being and Health in Patients With Chronic Heart Failure[NCT04871178] | 50 participants (Actual) | Interventional | 2010-10-10 | Completed | |||
| Heart Rate Lowering Efficacy and Respiratory Safety of Ivabradine in Patients With Obstructive Airway Disease[NCT01365286] | Phase 4 | 40 participants (Actual) | Interventional | 2009-05-31 | Completed | ||
| Verapamil as Adjunctive Seizure Therapy for Children and Young Adults With Dravet Syndrome[NCT01607073] | Phase 2 | 2 participants (Actual) | Interventional | 2012-04-30 | Completed | ||
| [NCT00000505] | Phase 3 | 0 participants | Interventional | 1983-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The secondary outcome measure is the change in number of absence seizures from Week 8 (Baseline) to Week 12 (NCT01607073)
Timeframe: Week 8 to Week 12
| Intervention | Abscence seizures (Number) |
|---|---|
| Week 8 Baseline | 165 |
| Week 12 Verapamil 4mg/kg/Day | 101 |
The primary study endpoint is the change in number of seizures from baseline. Since we only had one participant finish the study, the endpoint was changed to Week 12 visit. Participants were on verapamil for 4 weeks at Week 12. (NCT01607073)
Timeframe: Week 8 (baseline) to Week 12
| Intervention | General tonic-clonic seizures (Number) |
|---|---|
| Week 8 Baseline | 39 |
| Week 12 Verapamil 4mg/kg/Day | 14 |
The secondary outcome is the change in number of myoclonic seizures between baseline Week 8 visit and Week 12 visit. (NCT01607073)
Timeframe: Week 8 (baseline) to Week 12
| Intervention | Myoclonic seizures (Number) |
|---|---|
| Week 8 Baseline | 116 |
| Week 12 Verapamil 4mg/kg/Day | 175 |
10 reviews available for metoprolol and Angor Pectoris
| Article | Year |
|---|---|
[The benefits of carvedilol therapy in the treatment of patients with high cardiovascular risk].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Bisoprolol; Carbazoles; Cardi | 2016 |
Hypertrophic obstructive cardiomyopathy with multiple coronary arteries to right ventricular microfistulas: a case report and review of the literature.
Topics: Adult; Angina Pectoris; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Coronary Angiography; | 2017 |
beta-Adrenoceptor antagonists: new drugs and new indications.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Glaucoma; Humans; Hypertension; Kinetics; Me | 1981 |
Comparative review of beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Atenolol; Humans; Hypertension; | 1984 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans | 1984 |
New antiarrhythmic drugs.
Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half | 1983 |
Anti-ischaemic efficacy and tolerability of trimetazidine administered to patients with angina pectoris: results of three studies.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Drug To | 2001 |
Metoprolol: a review of its pharmacological properties and therapeutic efficacy in hypertension and angina pectoris.
Topics: Angina Pectoris; Animals; Blood Glucose; Dogs; Drug Interactions; Female; Hemodynamics; Humans; Hype | 1977 |
Oxidation phenotype and the metabolism and action of beta-blockers.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Drug Interactions; Ethanolamines; Humans; Hyp | 1985 |
Nifedipine and metoprolol in suspected unstable angina. Unstable angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Clinical T | 1987 |
135 trials available for metoprolol and Angor Pectoris
| Article | Year |
|---|---|
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Effect of PCI on quality of life in patients with stable coronary disease.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Angioplasty, Balloon, Coronary; Aspirin; C | 2008 |
Long-term stability of heart rate variability in chronic stable angina pectoris, and the impact of an acute myocardial infarction.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Coron | 2009 |
Aspects on the intensity and the relief of pain in the prehospital phase of acute coronary syndrome: experiences from a randomized clinical trial.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Analgesia; Analgesics | 2010 |
[Clinical-pharmacoeconomical aspects of ß-adrenoblockers use in patients with ischemic heart disease undergoing coronary artery bypass grafting].
Topics: Adrenergic beta-1 Receptor Antagonists; Angina Pectoris; Atenolol; Bisoprolol; Comparative Effective | 2010 |
Efficacy of trimetazidine in patients with recurrent angina: a subgroup analysis of the TRIMPOL II study.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angioplasty, Balloon, Coronary; Coronary Artery Bypass | 2004 |
Symptoms in patients with heart failure are prognostic predictors: insights from COMET.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Carbazoles; Carvedilol; Disease Progression; Dou | 2005 |
Favourable long term prognosis in stable angina pectoris: an extended follow up of the angina prognosis study in Stockholm (APSIS).
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Death, Sudden, Cardiac; Diab | 2006 |
[Cardioselective beta-adrenoblockers in patients with stable angina pectoris. Comparison of efficacy and safety].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzopyrans; Betaxolol; Bisoprolol; Blood Flow Velocit | 2006 |
Prognostic implications of renal dysfunction in patients with stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Calcium Channel Blockers; Cardiovascular Disease | 2006 |
Comparative clinical study of the efficacy and safety of a S-metoprolol ER tablet versus a racemate metoprolol ER tablet in patients with chronic stable angina.
Topics: Adrenergic beta-Antagonists; Aged; Analysis of Variance; Angina Pectoris; Blood Pressure; Chronic Di | 2007 |
Compliance, clinical outcome, and quality of life of patients with stable angina pectoris receiving once-daily betaxolol versus twice daily metoprolol: a randomized controlled trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Betaxolol; Dose-Response Relationship, Dr | 2007 |
Differential index: a simple time domain heart rate variability analysis with prognostic implications in stable angina pectoris.
Topics: Aged; Angina Pectoris; Cause of Death; Dose-Response Relationship, Drug; Double-Blind Method; Drug A | 2008 |
Comparison of five beta-adrenoreceptor antagonists with different ancillary properties during sustained twice daily therapy in angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Blood Pressure; Double-Blind Method; Exercise T | 1980 |
Beta-blocker therapy evaluated by radionuclide angiography: a study in chronic stable angina.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Cardiac Volume; Chronic Disease; Echoc | 1982 |
[Beta receptor blockers and calcium antagonists in coronary disease. Differential therapeutic aspects].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blocke | 1983 |
The use of beta-adrenergic blocking drugs in patients with myocardial infarction.
Topics: Adrenergic beta-Antagonists; Alprenolol; Angina Pectoris; Atenolol; Clinical Trials as Topic; Humans | 1984 |
Acute myocardial ischaemia: what information can be expected in the near future from ongoing clinical trials with nifedipine?
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Electrocardiography; Humans; Metoprolol | 1983 |
[Diurnal variation of angina pectoris attacks. Changes during treatment with beta-blockers].
Topics: Adult; Aged; Angina Pectoris; Circadian Rhythm; Clinical Trials as Topic; Delayed-Action Preparation | 1984 |
[Duration of action of sustained-release metoprolol in effort angina pectoris].
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; H | 1983 |
Orthostatic response before and after nitroglycerin in metoprolol- and verapamil-treated angina pectoris.
Topics: Aged; Angina Pectoris; Blood Pressure; Heart Rate; Humans; Hypotension, Orthostatic; Metoprolol; Mid | 1983 |
[Isosorbide dinitrate in exercise induced angina pectoris despite use of beta-blocking treatment. Clinical and hematological effects assessed by isotope angiocardiography].
Topics: Adult; Aged; Angina Pectoris; Angiocardiography; Clinical Trials as Topic; Double-Blind Method; Fema | 1982 |
Metoprolol in angina pectoris complicated by essential hypertension. A clinical comparison of the antianginal efficacy of metoprolol slow-release tablets (Durules) given once daily and propranolol tablets given twice daily.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; | 1981 |
Treatment of angina pectoris with metoprolol. A comparison between Durules administered once daily and tablets administered twice daily.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; F | 1981 |
Once-daily treatment of stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; | 1982 |
The symptomatic and objective effects of nifedipine in combination with beta-blocker therapy in severe angina pectoris.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Hu | 1982 |
Haemodynamic and clinical effects of isosorbide-dinitrate in patients with severe effort angina on beta-blocking treatment.
Topics: Adult; Aged; Angina Pectoris; Drug Therapy, Combination; Female; Hemodynamics; Humans; Isosorbide Di | 1983 |
A dose-response study on metoprolol in angina pectoris.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Dose-Response Relationship, Drug; Exercise Test; Fe | 1981 |
[Combined treatment of angina pectoris with nifedipine and metoprolol].
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Fem | 1981 |
A clinical evaluation of sustained release metoprolol durules in the treatment of angina pectoris.
Topics: Aged; Angina Pectoris; Delayed-Action Preparations; Humans; Metoprolol; Middle Aged; Propanolamines | 1982 |
Relative activities of atenolol and metoprolol on the cardiovascular system of man.
Topics: Adolescent; Adult; Angina Pectoris; Atenolol; Blood Pressure; Dose-Response Relationship, Drug; Hear | 1981 |
[Exercise tolerance in angina patients 3 and 24 hours after administration of a new delayed-action preparation of metoprolol].
Topics: Adult; Aged; Angina Pectoris; Delayed-Action Preparations; Female; Hemodynamics; Humans; Male; Metop | 1981 |
Effects of metoprolol on effort angina during the postprandial state.
Topics: Adult; Angina Pectoris; Blood Pressure; Eating; Heart Rate; Humans; Male; Metoprolol; Middle Aged; O | 1980 |
[Calcium antagonists and primary prevention of coronary disease].
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Double-Blind Method; Female; Humans; Male; Metoprolo | 1995 |
Felodipine versus placebo in stable effort-induced angina pectoris in patients inadequately controlled with metoprolol--a dose-finding study.
Topics: Aged; Angina Pectoris; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, | 1994 |
Usefulness of heart rate variability in predicting drug efficacy (metoprolol vs diltiazem) in patients with stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Angina Pectoris; Calcium Channel Blo | 1995 |
Selection of medical treatment in stable angina pectoris: results of the International Multicenter Angina Exercise (IMAGE) Study.
Topics: Angina Pectoris; Delayed-Action Preparations; Double-Blind Method; Electrocardiography; Exercise Tes | 1995 |
Comparison of efficacy of nisoldipine, metoprolol, and isosorbide dinitrate in patients with stable exertional angina: a randomized, cross-over, placebo-controlled study.
Topics: Administration, Oral; Aged; Angina Pectoris; Blood Pressure; Cross-Over Studies; Exercise Test; Exer | 1995 |
Platelet aggregability in vivo is attenuated by verapamil but not by metoprolol in patients with stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Catecholamines; Double-Blind Method; Humans; Male; Metoprolol; Middle | 1995 |
Intermittent transdermal nitrates do not improve ischemia in patients taking beta-blockers or calcium antagonists: potential role of rebound ischemia during the nitrate-free period.
Topics: Administration, Cutaneous; Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel B | 1995 |
The long-term effects of metoprolol and epanolol on tissue-type plasminogen activator and plasminogen activator inhibitor 1 in patients with ischaemic heart disease.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzeneacetamides; Blood Glucose; Blood Pressure; Doub | 1994 |
Efficacy of metoprolol and diltiazem in treating silent myocardial ischemia.
Topics: Adult; Aged; Angina Pectoris; Delayed-Action Preparations; Diltiazem; Drug Administration Schedule; | 1994 |
Conventional and controlled release diltiazem. Bioavailability in healthy volunteers and anti-anginal effects in combination with metoprolol in stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Biological Availability; Cross-Over Studies; Delayed-Action Preparatio | 1994 |
Atropine increases the accuracy of dobutamine stress echocardiography in patients taking beta-blockers.
Topics: Aged; Angina Pectoris; Atropine; Dobutamine; Drug Synergism; Echocardiography; Electrocardiography; | 1994 |
Effect of metoprolol and diltiazem on the total ischaemic burden in patients with chronic stable angina: a randomized controlled trial.
Topics: Angina Pectoris; Diltiazem; Electrocardiography, Ambulatory; Exercise Test; Female; Heart Rate; Huma | 1993 |
Transient myocardial ischemia during nifedipine therapy in stable angina pectoris, and its relation to coronary collateral flow and comparison with metoprolol.
Topics: Angina Pectoris; Collateral Circulation; Coronary Angiography; Coronary Circulation; Double-Blind Me | 1993 |
A double-blind comparison of nicorandil and metoprolol in stable effort angina pectoris.
Topics: Adult; Angina Pectoris; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Exerc | 1993 |
Combination therapy with metoprolol and nifedipine versus monotherapy in patients with stable angina pectoris. Results of the International Multicenter Angina Exercise (IMAGE) Study.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Drug Th | 1996 |
Effect of metoprolol on death and cardiac events during a 2-year period after coronary artery bypass grafting. The MACB Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Coronary Artery Bypass | 1995 |
Effects of metoprolol vs verapamil in patients with stable angina pectoris. The Angina Prognosis Study in Stockholm (APSIS)
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Double-Blind Me | 1996 |
Treatment of hypertension associated with stable angina pectoris: favourable interaction between new metoprolol formulation (OROS) and nifedipine.
Topics: Angina Pectoris; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blo | 1996 |
Fibrinolytic variables and cardiovascular prognosis in patients with stable angina pectoris treated with verapamil or metoprolol. Results from the Angina Prognosis study in Stockholm.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Cardiovascular System; Femal | 1997 |
Psychosocial variables in female vs male patients with stable angina pectoris and matched healthy controls.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Calcium Channel Blockers; Chi-Square Distributio | 1997 |
Cardiovascular prognosis in relation to apolipoproteins and other lipid parameters in patients with stable angina pectoris treated with verapamil or metoprolol: results from the Angina Prognosis Study in Stockholm (APSIS).
Topics: Aged; Angina Pectoris; Apolipoproteins; Cardiovascular System; Cholesterol; Cholesterol, HDL; Choles | 1997 |
Addition of felodipine to metoprolol vs replacement of metoprolol by felodipine in patients with angina pectoris despite adequate beta-blockade. Results of the Felodipine ER and Metoprolol CR in Angina (FEMINA) Study. Working Group on Cardiovascular Resea
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Dou | 1997 |
Effects on heart rate variability of isosorbide-5-mononitrate and metoprolol in patients with recent onset of angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Electrocardiography, A | 1998 |
Comparison of safety and efficacy of carvedilol and metoprolol in stable angina pectoris.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Age Factors; Aged; Angina Pectoris; Antio | 1999 |
A comparison of metoprolol and morphine in the treatment of chest pain in patients with suspected acute myocardial infarction--the MEMO study.
Topics: Adrenergic beta-Antagonists; Aged; Analgesics, Opioid; Angina Pectoris; Diagnosis, Differential; Fem | 1999 |
Antianginal efficacy of the combination of felodipine-metoprolol 10/100 mg compared with each drug alone in patients with stable effort-induced angina pectoris: a multicenter parallel group study. The TRAFFIC Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Double-Blind Me | 1999 |
Prognostic implications of ambulatory myocardial ischemia and arrhythmias and relations to ischemia on exercise in chronic stable angina pectoris (the Angina Prognosis Study in Stockholm [APSIS]).
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Elect | 1999 |
Inflammatory and hemostatic markers in relation to cardiovascular prognosis in patients with stable angina pectoris. Results from the APSIS study. The Angina Prognosis Study in Stockholm.
Topics: Adrenergic beta-Agonists; Aged; Angina Pectoris; beta-Thromboglobulin; Calcium Channel Blockers; Car | 2000 |
Prognostic implications of results from exercise testing in patients with chronic stable angina pectoris treated with metoprolol or verapamil. A report from the Angina Prognosis Study In Stockholm (APSIS).
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Exerc | 2000 |
Prognostic implications of intima-media thickness and plaques in the carotid and femoral arteries in patients with stable angina pectoris.
Topics: Aged; Angina Pectoris; Arteriosclerosis; Carotid Arteries; Carotid Artery Diseases; Coronary Artery | 2001 |
Amlodipine versus slow release metoprolol in the treatment of stable exertional angina pectoris (AMSA).
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angina Pectoris; Calcium Channel Blockers; Delayed-Ac | 2000 |
Silent ischemic interval on exercise test is a predictor of response to drug therapy: a randomized crossover trial of metoprolol versus diltiazem in stable angina.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Cross-Over Stud | 2001 |
Circadian variation of heart rate variability and the rate of autonomic change in the morning hours in healthy subjects and angina patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Aortic Bodies; Autonom | 2001 |
Combination treatment in stable effort angina using trimetazidine and metoprolol: results of a randomized, double-blind, multicentre study (TRIMPOL II). TRIMetazidine in POLand.
Topics: Administration, Oral; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Double- | 2001 |
Prognostic implications of autonomic function assessed by analyses of catecholamines and heart rate variability in stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Anti-Arrhythmia Agents; Autonomic Nervous System Diseases; Biomarkers; | 2002 |
An eighteen months' study of the clinical response to metoprolol, a selective beta1-receptor blocking agent, in patients with angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Exercise Test; | 1976 |
A comparative study of three beta 1-adrenoreceptor blocking drugs with different degree of intrinsic stimulating activity (metoprolol, practolol and H 87/07) in patients with angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Heart Rate; Humans; Metoprolol; Physic | 1978 |
[Effect of metoprolol on systolic time in patients with stable angina pectoris].
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; | 1979 |
Slow-release metoprolol in angina pectoris. A comparative study of a cardioselective beta-blocking drug, metoprolol, in ordinary and slow-release tablets (Durules) in the treatment of angina pectoris.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Angina Pectoris; Blood Pressure; Clinical T | 1979 |
[Metoprolol effect on ECG exercise test in patients with stable angina pectoris. Computer analysis (author's transl)].
Topics: Adult; Angina Pectoris; Electrocardiography; Exercise Test; Heart Rate; Hemodynamics; Humans; Male; | 1979 |
[Effect of metoprolol on the exercise tolerance in patients with stable angina pectoris (author's transl)].
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Exercise Tes | 1978 |
Antianginal efficiency of nifedipine with and without a beta-blocker, studied with exercise test. A double-blind, randomized subacute study.
Topics: Aged; Alprenolol; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Dr | 1979 |
[Effects of metoprolol acute administration on effort tolerance in patients affected by stable effort angina. Comparison with placebo and propranolol (author's transl)].
Topics: Adult; Aged; Angina Pectoris; Exercise Test; Female; Heart Rate; Hemodynamics; Humans; Male; Metopro | 1979 |
Comparison of the immediate effects of five beta-adrenoreceptor-blocking drugs with different ancillary properties in angina pectoris.
Topics: Adult; Angina Pectoris; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation; Electroca | 1979 |
Double-blind titrated-dose comparison of metoprolol and propranolol in the treatment of angina pectoris.
Topics: Adult; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Heart Rate; Human | 1976 |
Assessment of metoprolol, a cardioselective beta-blocking agent, during chronic therapy in patients with angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Drug Evaluation; Heart Rate; | 1976 |
Efficacy of epanolol versus metoprolol in angina pectoris: report from a Swedish multicentre study of exercise tolerance.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzeneacetamides; Double-Blind Method; Exercise Test; | 1992 |
Amlodipine in patients with stable angina pectoris treated with nitrates and beta-blockers. The influence on exercise tolerance, systolic and diastolic functions of the left ventricle.
Topics: Amlodipine; Angina Pectoris; Diastole; Dose-Response Relationship, Drug; Drug Administration Schedul | 1992 |
Invasive versus conservative strategy after thrombolytic therapy for acute myocardial infarction in patients with antecedent angina. A report from Thrombolysis in Myocardial Infarction Phase II (TIMI II).
Topics: Administration, Oral; Aged; Angina Pectoris; Cardiac Catheterization; Combined Modality Therapy; Cor | 1992 |
Long-term efficacy of diltiazem controlled release versus metoprolol in patients with stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Delayed-Action Preparations; Diltiazem; Double-Blind M | 1991 |
Attenuation of circadian variation by combined antianginal therapy with suppression of morning and evening increases in transient myocardial ischemia.
Topics: Angina Pectoris; Circadian Rhythm; Coronary Disease; Double-Blind Method; Drug Therapy, Combination; | 1991 |
A comparison of metoprolol OROS with antenolol in the treatment of effort angina pectoris: a randomized double-blind study.
Topics: Adult; Aged; Angina Pectoris; Atenolol; Blood Pressure; Delayed-Action Preparations; Double-Blind Me | 1991 |
Exercise-induced platelet aggregation in angina and its possible prevention by beta 1-selective blockade.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Cyclic AMP; Epinephrine; Exercise; Humans; Male; Metop | 1990 |
Transient myocardial ischemia during daily life in rest and exertional angina pectoris and comparison of effectiveness of metoprolol versus nifedipine.
Topics: Angina Pectoris; Circadian Rhythm; Coronary Angiography; Coronary Disease; Double-Blind Method; Elec | 1991 |
[The use of metoprolol with calcium antagonists of different mechanisms of action (diltiazem and nifedipine) in patients with stenocardia of effort].
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Diltiazem; Drug Therapy, Combina | 1990 |
[Comparison of antianginal effects of diltiazem and metoprolol in patients with ischemic heart disease with different clinical forms of angina pectoris].
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Diltiazem; Humans; Metoprolol; Middle Aged; Randomiz | 1990 |
Mortality and morbidity during one year of follow-up in suspected acute myocardial infarction in relation to early diagnosis: experiences from the MIAMI trial.
Topics: Angina Pectoris; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Humans; Incide | 1990 |
Effects of benazepril and metoprolol OROS alone and in combination on myocardial ischemia in patients with chronic stable angina.
Topics: Adult; Aged; Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Coronary Disea | 1990 |
Early treatment of unstable angina with nifedipine and metoprolol--the HINT trial.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Fem | 1988 |
Nifedipine and metoprolol in unstable angina: findings from the Holland Interuniversity Nifedipine/Metoprolol Trial (HINT).
Topics: Aged; Angina Pectoris; Angina, Unstable; Double-Blind Method; Drug Therapy, Combination; Electrocard | 1987 |
Noradrenergic activity and silent ischaemia in hypertensive patients with stable angina: effect of metoprolol.
Topics: Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Coronary Disease; Double-Blind Method; El | 1989 |
[Ways of individualizing use of anti-anginal preparations].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Clinical Trials as Topic; Dose-Response Relationship, | 1989 |
Comparative multicentre study of the tolerability and efficacy of epanolol versus metoprolol in patients with stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Benzeneacetamides; Dru | 1989 |
Efficacy of epanolol versus metoprolol in angina pectoris. Results from the Swedish Multicenter Study of Exercise Tolerance. The Swedish Multicenter Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Benzeneacetamides; Exercise Test; Female; | 1989 |
Effects of epanolol and metoprolol on the heart measured by 24-hour holter monitoring.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angina Pectoris; Benzeneacetamides; Ele | 1989 |
Sustained-release diltiazem versus metoprolol in stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Drug Eval | 1989 |
[Comparative anti-angina effectiveness of metoprolol and propranolol].
Topics: Adult; Angina Pectoris; Anti-Arrhythmia Agents; Clinical Trials as Topic; Exercise Test; Humans; Mal | 1989 |
Cardioselective beta-blockade with metoprolol in rest angina: a randomized, double-blind, placebo-controlled, cross-over trial.
Topics: Aged; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; H | 1989 |
[Do thrombocyte aggregation inhibitors modify silent episodes of unstable angina pectoris in combined anti-angina therapy?].
Topics: Aged; Angina Pectoris; Angina, Unstable; Aspirin; Coronary Circulation; Diltiazem; Drug Therapy, Com | 1989 |
[TTS-nitroglycerin and slow-release metoprolol: efficacy in patients with stable exercise-induced angina].
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Arterial Occlusive Diseases; Clinical Trials as | 1985 |
Metoprolol in acute myocardial infarction. Narcotic analgesics and other antianginal drugs. The MIAMI Trial Research Group.
Topics: Analgesics, Opioid; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Trials as To | 1985 |
Early treatment of unstable angina in the coronary care unit: a randomised, double blind, placebo controlled comparison of recurrent ischaemia in patients treated with nifedipine or metoprolol or both. Report of The Holland Interuniversity Nifedipine/Meto
Topics: Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Care Units; Double-Blind | 1986 |
Efficacy of nifedipine and metoprolol in the early treatment of unstable angina in the coronary care unit: findings from the Holland Interuniversity Nifedipine/metoprolol Trial (HINT).
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coro | 1987 |
Comparison of selective (beta 1) and nonselective (beta 1 and beta 2) beta-adrenergic blockade on systemic and coronary hemodynamic findings in angina pectoris.
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Coronary Circulation; Double-Blind Method; Exer | 1987 |
Adenosine-provoked angina pectoris-like pain--time characteristics, influence of autonomic blockade and naloxone.
Topics: Adenosine; Adrenergic beta-Antagonists; Adult; Angina Pectoris; Electrocardiography; Female; Heart B | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Unstable angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Clinical T | 1987 |
Comparative effects of metoprolol and celiprolol on cardiac hemodynamics and left ventricular volume at rest and during exercise-induced angina.
Topics: Angina Pectoris; Celiprolol; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Evaluat | 1986 |
Metoprolol, nifedipine, and the combination in stable effort angina pectoris.
Topics: Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, | 1986 |
Randomized double-blind comparison of metoprolol, nifedipine, and their combination in chronic stable angina: effects on total ischemic activity and heart rate at onset of ischemia.
Topics: Angina Pectoris; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Heart | 1988 |
Diltiazem in comparison with metoprolol in stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Exercise Tes | 1988 |
Early treatment of unstable angina in the coronary care unit: a randomised, double blind, placebo controlled comparison of recurrent ischaemia in patients treated with nifedipine or metoprolol or both.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Comb | 1988 |
Hemodynamic effects of metoprolol and nifedipine in angina pectoris measured by isotope technique.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Drug Therapy, Combination; Female; Hemodynam | 1988 |
Nifedipine and metoprolol in suspected unstable angina. The Holland Interuniversity Nifedipine/Metoprolol Trial.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Comb | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Principles of intervention research.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Ethics, Medical; Humans; Metoprolol; Ne | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Formation of the HINT cohort.
Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Electrocardiography; Femal | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Data analysis.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Data Interpretation, Statistical; Doubl | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Planning and conduct.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Comb | 1987 |
Nifedipine and metoprolol in suspected unstable angina. Treatment, observations, and outcome events.
Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug | 1987 |
Double-blind comparison of long acting propranolol and sustained release metoprolol in the treatment of angina pectoris.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; | 1987 |
ST 567 (alinidine) in stable angina: a comparison with metoprolol.
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Clinical Trials as Topic; Clonidine; Double-Blind Method; E | 1987 |
The antianginal efficacy and tolerability of controlled-release metoprolol once daily: a comparison with conventional metoprolol tablets twice daily.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Delayed-Action Preparations; Double-Blind Method; D | 1988 |
The influence of early intervention in acute myocardial infarction on long-term mortality and morbidity as assessed in the Göteborg metoprolol trial.
Topics: Adult; Aged; Angina Pectoris; Clinical Trials as Topic; Disability Evaluation; Follow-Up Studies; Hu | 1986 |
Effects of nifedipine on left ventricular performance in unstable angina pectoris during a follow-up of 48 hours.
Topics: Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Female; Heart; Heart Ventricles; Hum | 1986 |
Influence of nifedipine on left ventricular perfusion and function in patients with unstable angina: evaluation with radionuclide techniques.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Circulation; Double-Blind Meth | 1986 |
Pharmacokinetic interaction between oral metoprolol and verapamil for angina pectoris.
Topics: Administration, Oral; Adult; Angina Pectoris; Clinical Trials as Topic; Drug Interactions; Drug Ther | 1986 |
Time sequence of anginal pain.
Topics: Adult; Aged; Angina Pectoris; Circadian Rhythm; Female; Humans; Isosorbide Dinitrate; Male; Metoprol | 1986 |
A haemodynamic study of the effects of combined slow-calcium channel blockade (nisoldipine) and beta-blockade (metoprolol) in coronary heart disease.
Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Hemod | 1986 |
Combination of metoprolol with molsidomine in the treatment of angina pectoris.
Topics: Aged; Angina Pectoris; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; Metoprolol; | 1985 |
Long-term treatment with metoprolol after myocardial infarction: effect on 3 year mortality and morbidity.
Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Cerebrovascular Disorders; Clinical Trials as Topic; Co | 1985 |
The effects on left ventricular performance of verapamil and metoprolol singly and together in exercise-induced angina pectoris.
Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Hear | 1985 |
Left ventricular performance in unstable angina: assessment with radionuclide techniques.
Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Angiography; Coronary Disease; | 1985 |
Effect of short and long term administration of amiodarone on ischaemia-induced left ventricular dysfunction. Implications for combined antianginal drug therapy.
Topics: Adult; Amiodarone; Angina Pectoris; Benzofurans; Coronary Disease; Female; Hemodynamics; Humans; Mal | 1985 |
Haemodynamic analysis of the effects of nicardipine and metoprolol alone and in combination in coronary artery disease.
Topics: Adult; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Therapy, Combination; Femal | 1985 |
70 other studies available for metoprolol and Angor Pectoris
| Article | Year |
|---|---|
Coronary artery fistula with associated Takotsubo cardiomyopathy: a case report.
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Aspirin; Cardiac Catheterization; Catecholamines; Chest Pai | 2018 |
[First fixed combination becomes available].
Topics: Angina Pectoris; Benzazepines; Coronary Disease; Drug Combinations; Humans; Ivabradine; Metoprolol | 2016 |
[Anti-angina fixed combination is available].
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Benzazepines; Cardiovascular Agents; Combined Modal | 2016 |
[Increased physical capacity].
Topics: Angina Pectoris; Benzazepines; Cardiovascular Agents; Clinical Trials as Topic; Coronary Disease; Do | 2016 |
Perioperative beta blockade.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Comorbidity; Humans; Hypotension; Intraoperative Compl | 2008 |
Hemodynamic effect of myocardial bridging.
Topics: Adenosine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angina Pectoris; Atropine; Bicycli | 2009 |
Multiple coronary-cameral fistulae causing angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Angiography; Coronary Artery Disease; Echocar | 2009 |
Haemodynamic effects of acute intravenous metoprolol in apical ballooning syndrome with dynamic left ventricular outflow tract obstruction.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Female; Heart Ventricles; Hemodynamics; Humans; Inject | 2010 |
Multiple coronary cameral fistulae: a rare anomaly and cause of ischaemia.
Topics: Aged, 80 and over; Angina Pectoris; Antihypertensive Agents; Coronary Angiography; Coronary Vessel A | 2012 |
[Clinical and metabolic effects of cardioselective beta-adrenoblockers nebivolol and metoprolol in patients with hypertension and ischemic heart disease associated with type 2 diabetes].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Benzopyrans; Carbohydrate Met | 2003 |
The impact of diabetes or elevated fasting blood glucose on cardiovascular prognosis in patients with stable angina pectoris.
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Blood Glucose; Cardiovascular Diseases; Diabetic Angiopathi | 2005 |
The anti-ischemic effect of metoprolol in patients with chronic angina pectoris is gender-specific.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Blood Pressure; Chronic Disease; Exercise Test; | 2006 |
Hymenoptera sting-induced Kounis syndrome: effects of aspirin and beta-blocker administration.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Animals; Anti-Inflammatory Agents, Non-Steroidal | 2007 |
Clinical use of the beta1-selective adrenoceptor blocker metoprolol in hypertension, angina pectoris and arrhythmias.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Humans; Hypertension; Metoprolol | 1981 |
Managing angina with beta blockers.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Humans; Metoprolol; Nadolol; Nitrates; Propa | 1982 |
Update on drug therapy: III. Metoprolol.
Topics: Angina Pectoris; Humans; Hypertension; Metoprolol; Propanolamines | 1980 |
Treatment of unstable angina with emphasis on calcium antagonists.
Topics: Angina Pectoris; Angina, Unstable; Anticoagulants; Coronary Circulation; Coronary Disease; Electroca | 1984 |
Antianginal drug effects on normal, ischemic and scar myocardial segments in man.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Female; Heart; Humans; Male; Metoprolol; Middle Aged | 1984 |
Studies with long acting propranolol.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Delayed-Action Preparations; Half-Life; Heart Rate; Humans; H | 1984 |
Probable adverse interaction between oral metoprolol and verapamil.
Topics: Angina Pectoris; Drug Interactions; Drug Therapy, Combination; Heart Block; Humans; Male; Metoprolol | 1984 |
The effect on left ventricular performance of nifedipine and metoprolol singly and together in exercise-induced angina pectoris.
Topics: Adult; Angina Pectoris; Cardiac Output; Drug Therapy, Combination; Heart Ventricles; Hemodynamics; H | 1984 |
Prinzmetal's variant angina.
Topics: Aged; Angina Pectoris; Angina Pectoris, Variant; Diagnosis, Differential; Electrocardiography; Femal | 1981 |
Thyrotoxic crisis masked by treatment with beta-blockers.
Topics: Angina Pectoris; Humans; Male; Metoprolol; Middle Aged; Propanolamines; Thyroid Crisis | 1981 |
[Electrocardiographic differential diagnosis of ischemic and aspecific anomalies of ventricular repolarization].
Topics: Adult; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Female; Humans; Male; | 1980 |
Comparison of metoprolol and verapamil in the treatment of angina pectoris.
Topics: Adult; Angina Pectoris; Double-Blind Method; Female; Humans; Male; Metoprolol; Middle Aged; Nitrogly | 1982 |
Peripheral vasospasm during beta-receptor blockade - a comparison between metoprolol and pindolol.
Topics: Adult; Angina Pectoris; Forearm; Humans; Male; Metoprolol; Middle Aged; Pindolol; Propanolamines; Ra | 1982 |
Hemodynamic consequences of combined beta-adrenergic and slow calcium channel blockade in man.
Topics: Adult; Aged; Angina Pectoris; Coronary Disease; Drug Therapy, Combination; Electrocardiography; Fema | 1982 |
Cardiac safety of acute beta blockade: intrinsic sympathomimetic activity is superior to beta-1 selectivity.
Topics: Adult; Aged; Angina Pectoris; Drug Evaluation; Echocardiography; Exercise Test; Female; Heart Ventri | 1982 |
[Metoprolol in angina pectoris].
Topics: Aged; Angina Pectoris; Double-Blind Method; Exercise Test; Female; Humans; Male; Metoprolol; Middle | 1981 |
A pharmacokinetic comparison between different slow-release formulations of metoprolol (Lopresor SR and Betaloc SA)
Topics: Adult; Angina Pectoris; Delayed-Action Preparations; Humans; Hypertension; Kinetics; Metoprolol; Mid | 1981 |
[Long duration of action of metoprolol in the prolonged treatment of angina of effort].
Topics: Aged; Angina Pectoris; Drug Evaluation; Exercise Test; Female; Hemodynamics; Humans; Male; Metoprolo | 1981 |
[Disparate efficacy of isosorbide dinitrate, in sustained-release form, during acute and chronic administration (author's transl)].
Topics: Angina Pectoris; Blood Pressure; Delayed-Action Preparations; Dose-Response Relationship, Drug; Doub | 1980 |
[Drug therapy of angina pectoris. Are the possibilities exploited well enough?].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Angina, Unstable; Female; Humans; Isosorb | 1995 |
Interaction of metoprolol and fluoxetine.
Topics: Angina Pectoris; Depressive Disorder; Drug Interactions; Fluoxetine; Humans; Male; Metoprolol; Middl | 1993 |
Doppler sonographic examination of the internal mammary artery graft: influence of exercise.
Topics: Adult; Aged; Angina Pectoris; Blood Flow Velocity; Coronary Disease; Echocardiography, Doppler; Exer | 1993 |
Ten year mortality in relation to original size of myocardial infarct: results from the Gothenburg metoprolol study.
Topics: Adult; Aged; Angina Pectoris; Diabetes Complications; Female; Follow-Up Studies; Humans; Hypertensio | 1994 |
Primary prevention in patients with coronary heart disease: the APSIS study.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Female; Hu | 1995 |
Relation between dynamic midventricular obstruction and unexplained chest pain in patients with normal echocardiograms at rest.
Topics: Acebutolol; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angina P | 1996 |
[Stable angina pectoris: what is the role of calcium antagonists?].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel Blockers; Clinical Trials as | 1997 |
[Time-dependent effect of metoprolol in middle-aged and old patients with angina].
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Angina Pectoris; Circadian Rhythm; Humans; Metoprol | 1997 |
[Ticlopidine-induced cholestasis].
Topics: Aged; Aged, 80 and over; Angina Pectoris; Aspirin; Chemical and Drug Induced Liver Injury; Cholestas | 1999 |
[Anti-angina treatment and impotence].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Erectile Dysfunction; Humans; Male; Metoprolol; Middle | 2000 |
Beta-blocker withdrawal syndrome?
Topics: Angina Pectoris; Humans; Male; Metoprolol; Middle Aged; Myocardial Infarction; Propanolamines; Recur | 1979 |
Beta-blocker withdrawal syndrome?
Topics: Angina Pectoris; Humans; Metoprolol; Nifedipine; Propanolamines; Substance Withdrawal Syndrome | 1979 |
[The effect of nitroglycerin and of a new beta-blocking agent (metroprlolo) on exercise tolerance in ischemic patients].
Topics: Adult; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; Female; Hemodynamics; | 1978 |
Drugs in current use: metoprolol.
Topics: Adult; Aged; Angina Pectoris; Child; Female; Humans; Hypertension; Metoprolol; Pregnancy; Propanolam | 1979 |
Some observations of the long-term clinical response to selective beta-blockade (metoprolol) in angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Female; Follow-Up Studies; Humans; Male; Metoprolol; Middle Aged; Prop | 1977 |
[Therapy of coronary disease].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Aspirin; Calcium Channel Blockers; Clinical Trials as | 1992 |
Epanolol as a model for assessing patient preference in anti-anginal drug therapy.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzeneacetamides; Choice Behavior; Female; Humans; Ma | 1992 |
Paradoxical effect of long-term treatment of nifedipine on total ischemic load in patients with stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Diltiazem; Electrocardiography, Ambulatory; Exercise Test; Female; Hea | 1992 |
Effects of diltiazem and long-term beta 1-adrenergic blockade on hemodynamics and blood flow during exercise in patients with stable angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Cardiac Output; Diltiazem; Exercise; Hemodyn | 1990 |
[Acute changes of coronary and global hemodynamics in patients with angina pectoris and arterial hypertension caused by celiprolol and metoprolol].
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Celiprolol; Hemodynamics; Humans; Hypertension; | 1990 |
Is there a role for angiotensin-converting enzyme inhibitors in the treatment of chronic myocardial ischemia?
Topics: Angina Pectoris; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Coronary Disease; Delayed-A | 1990 |
Application of time series analysis to circadian rhythms: effect of beta-adrenergic blockade upon heart rate and transient myocardial ischemia.
Topics: Angina Pectoris; Circadian Rhythm; Electrocardiography, Ambulatory; Fourier Analysis; Heart Rate; Hu | 1990 |
Left ventricular function during treatment with either metoprolol or epanolol.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Benzeneacetamides; Blood Pressure; Heart Rate; Humans; | 1989 |
Quality of life five years after myocardial infarction.
Topics: Angina Pectoris; Anxiety Disorders; Dyspnea; Female; Follow-Up Studies; Humans; Male; Metoprolol; My | 1989 |
Tolerability of combined treatment with verapamil and beta-blockers in angina resistant to monotherapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Atenolol; Drug Therapy, Combination; Drug | 1985 |
[Drug combinations in the treatment of exertion angina. II].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Calcium Channel Blockers; Double-Blind Method; Drug Th | 1986 |
Effect of beta-blockers on the relation between QT-interval and heart rate in exercise ECG.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Coronary Disease; Electrocardiography; Exercise Test; | 1987 |
Differential effects of timolol and metoprolol on platelet function at rest and during exercise.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Blood Platelets; Double-Blind Method; Epi | 1988 |
Altered hemodynamic response to dobutamine in relation to the degree of preoperative beta-adrenoceptor blockade.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Atenolol; Bupranolol; Dobutamine; Hemodyn | 1988 |
[Effects of a new positive inotropic agent, OPC-8212 in patients with effort angina--comparison with beta-blocker, metoprolol].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Cardiotonic Agents; Electrocardiography; | 1988 |
Bradycardia induced by an interaction between phenelzine and beta blockers.
Topics: Aged; Angina Pectoris; Bradycardia; Depressive Disorder; Drug Interactions; Drug Therapy, Combinatio | 1989 |
Serum potassium values in relation to the use of diuretics in patients with unstable angina pectoris.
Topics: Angina Pectoris; Angina, Unstable; Coronary Disease; Diuretics; Female; Humans; Hypokalemia; Male; M | 1988 |
Severe complications of antianginal drug therapy in a patient identified as a poor metabolizer of metoprolol, propafenone, diltiazem, and sparteine.
Topics: Angina Pectoris; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Heart Block | 1987 |
Improvement by oral metoprolol of exercise-induced ischemic dysfunction in patients with coronary heart disease.
Topics: Administration, Oral; Adult; Angina Pectoris; Blood Pressure; Coronary Disease; Heart Rate; Humans; | 1986 |
Addition of nifedipine to maximal beta-blocker-nitrate therapy: effects on exercise capacity and global left ventricular performance at rest and during exercise.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Electrocar | 1985 |
Improvement in exercise capacity and associated changes in hemodynamics and left ventricular function after the addition of metoprolol to nifedipine in patients with stable exertional angina.
Topics: Administration, Oral; Adult; Angina Pectoris; Cardiac Output; Drug Therapy, Combination; Electrocard | 1985 |
Clearance-based oral drug interaction between verapamil and metoprolol and comparison with atenolol.
Topics: Administration, Oral; Angina Pectoris; Atenolol; Drug Interactions; Drug Therapy, Combination; Femal | 1985 |
Induction of delayed repolarization during chronic beta-receptor blockade.
Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Electrocardiography; Heart Conduction System; Heart Rat | 1985 |