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metoprolol and Angina at Rest

metoprolol has been researched along with Angina at Rest in 24 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Research Excerpts

ExcerptRelevanceReference
"We explored whether vascular protection by carvedilol could contribute to its superior effects in the treatment of heart failure (HF) compared with metoprolol tartrate in the COMET (Carvedilol Or Metoprolol European Trial) study."9.12Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET. ( Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Metra, M; Moullet, C; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C, 2007)
"We explored whether vascular protection by carvedilol could contribute to its superior effects in the treatment of heart failure (HF) compared with metoprolol tartrate in the COMET (Carvedilol Or Metoprolol European Trial) study."5.12Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET. ( Cleland, JG; Di Lenarda, A; Komajda, M; Lukas, MA; Metra, M; Moullet, C; Poole-Wilson, PA; Remme, WJ; Scherhag, A; Spark, P; Swedberg, K; Torp-Pedersen, C, 2007)
"26 patients with unstable angina pectoris were enrolled in the study."2.68[Analysis of heart rhythm variability in evaluation of treatment for unstable angina pectoris]. ( Petelenz, T; Skrzypek-Wańha, J; Sosnowski, M; Słomińska-Petelenz, T, 1995)
" Metoprolol showed a considerable rectal bioavailability (AUC, C max) and was absorbed quickly from the rectum (T max)."1.30The relative bioavailability of metoprolol following oral and rectal administration to volunteers and patients. ( Beysens, AJ; de Stoppelaar, FM; Gorgels, AP; Stappers, JL; Stolk, LM, 1999)
"Metoprolol was added in seven patients and led to a decrease in double product (-2."1.28Myocardial metabolic and hemodynamic effects of a sustained intravenous infusion of nifedipine with and without metoprolol in patients with unstable angina. ( Bargossi, A; Branzi, A; Degli Esposti, D; Fallani, F; Magnani, B; Melandri, G; Motta, R; Piazzi, S; Tartagni, F, 1991)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199016 (66.67)18.7374
1990's7 (29.17)18.2507
2000's1 (4.17)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Remme, WJ1
Torp-Pedersen, C1
Cleland, JG1
Poole-Wilson, PA1
Metra, M1
Komajda, M1
Swedberg, K1
Di Lenarda, A1
Spark, P1
Scherhag, A1
Moullet, C1
Lukas, MA1
Hugenholtz, PG2
Michels, R1
Serruys, PW1
Simoons, ML4
Forfang, K1
Gullestad, L1
Petelenz, T1
Sosnowski, M1
Skrzypek-Wańha, J1
Słomińska-Petelenz, T1
Singh, N1
Mironov, D1
Goodman, S1
Morgan, CD1
Langer, A1
Nozawa, T1
Inoue, H1
de Stoppelaar, FM1
Stolk, LM1
Beysens, AJ1
Stappers, JL1
Gorgels, AP1
Morelli, S1
Gurgo, AM1
Martocchia, A1
Falaschi, P1
Melandri, G1
Branzi, A1
Tartagni, F1
Degli Esposti, D1
Piazzi, S1
Motta, R1
Bargossi, A1
Fallani, F1
Magnani, B1
Tijssen, JG7
Lubsen, J8
Eber, B1
Klein, W1
Fluch, N1
Dusleag, J1
Weinrauch, V1
Rotman, B1
Gasser, R1
Kronberger-Schaffer, E1
de Feijter, PJ2
van Gilst, WH1
van Es, GA1
Weihrauch, T1
Baumann, J1
Ebner, F1
Kerkkamp, HJ4
Lie, KI3
Viersma, JW1
de Beijer, JM1
van der Wall, EE2
van Rijk, PP2
Reiber, JH2
Bom, N2
Lubsen, JC1
Roos, JP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Trial of Influenza Vaccine to Prevent Adverse Vascular Events: A Pilot Study[NCT01945268]Phase 4107 participants (Actual)Interventional2015-04-30Completed
A Randomized Controlled Trial of Influenza Vaccine to Prevent Adverse Vascular Events[NCT02762851]Phase 45,000 participants (Anticipated)Interventional2016-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for metoprolol and Angina at Rest

ArticleYear
[Treatment with beta-blockers in patients with acute coronary syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:10

    Topics: Acute Disease; Adrenergic beta-Antagonists; Angina, Unstable; Atenolol; Clinical Trials as Topic; Co

1998
Thyrotoxicosis, unstable angina and normal coronary angiogram.
    Giornale italiano di cardiologia, 1999, Volume: 29, Issue:11

    Topics: Angina, Unstable; Anti-Arrhythmia Agents; Chest Pain; Combined Modality Therapy; Coronary Angiograph

1999
Nifedipine and metoprolol in suspected unstable angina. Unstable angina pectoris.
    European heart journal, 1987, Volume: 8 Suppl H

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Clinical T

1987

Trials

17 trials available for metoprolol and Angina at Rest

ArticleYear
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
    Journal of the American College of Cardiology, 2007, Mar-06, Volume: 49, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl

2007
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
    Journal of the American College of Cardiology, 2007, Mar-06, Volume: 49, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl

2007
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
    Journal of the American College of Cardiology, 2007, Mar-06, Volume: 49, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl

2007
Carvedilol protects better against vascular events than metoprolol in heart failure: results from COMET.
    Journal of the American College of Cardiology, 2007, Mar-06, Volume: 49, Issue:9

    Topics: Adrenergic beta-Antagonists; Angina, Unstable; Carbazoles; Carvedilol; Death, Sudden, Cardiac; Doubl

2007
[Analysis of heart rhythm variability in evaluation of treatment for unstable angina pectoris].
    Polskie Archiwum Medycyny Wewnetrznej, 1995, Volume: 94, Issue:1

    Topics: Adult; Aged; Angina, Unstable; Anti-Arrhythmia Agents; Coronary Angiography; Exercise Test; Female;

1995
Treatment of silent ischemia in unstable angina: a randomized comparison of sustained-release verapamil versus metoprolol.
    Clinical cardiology, 1995, Volume: 18, Issue:11

    Topics: Adrenergic beta-Antagonists; Aged; Angina, Unstable; Calcium Channel Blockers; Delayed-Action Prepar

1995
Nifedipine and metoprolol in unstable angina: findings from the Holland Interuniversity Nifedipine/Metoprolol Trial (HINT).
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 2

    Topics: Aged; Angina Pectoris; Angina, Unstable; Double-Blind Method; Drug Therapy, Combination; Electrocard

1987
[Do thrombocyte aggregation inhibitors modify silent episodes of unstable angina pectoris in combined anti-angina therapy?].
    Zeitschrift fur Kardiologie, 1989, Volume: 78 Suppl 2

    Topics: Aged; Angina Pectoris; Angina, Unstable; Aspirin; Coronary Circulation; Diltiazem; Drug Therapy, Com

1989
Early treatment of unstable angina in the coronary care unit: a randomised, double blind, placebo controlled comparison of recurrent ischaemia in patients treated with nifedipine or metoprolol or both. Report of The Holland Interuniversity Nifedipine/Meto
    British heart journal, 1986, Volume: 56, Issue:5

    Topics: Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Care Units; Double-Blind

1986
Efficacy of nifedipine and metoprolol in the early treatment of unstable angina in the coronary care unit: findings from the Holland Interuniversity Nifedipine/metoprolol Trial (HINT).
    The American journal of cardiology, 1987, Jul-15, Volume: 60, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coro

1987
Nifedipine and metoprolol in suspected unstable angina. Unstable angina pectoris.
    European heart journal, 1987, Volume: 8 Suppl H

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina, Unstable; Calcium Channel Blockers; Clinical T

1987
Early treatment of unstable angina in the coronary care unit: a randomised, double blind, placebo controlled comparison of recurrent ischaemia in patients treated with nifedipine or metoprolol or both.
    British heart journal, 1988, Volume: 59, Issue:2

    Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Comb

1988
Nifedipine and metoprolol in suspected unstable angina. The Holland Interuniversity Nifedipine/Metoprolol Trial.
    European heart journal, 1987, Volume: 8 Suppl H

    Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Comb

1987
Nifedipine and metoprolol in suspected unstable angina. Principles of intervention research.
    European heart journal, 1987, Volume: 8 Suppl H

    Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Ethics, Medical; Humans; Metoprolol; Ne

1987
Nifedipine and metoprolol in suspected unstable angina. Formation of the HINT cohort.
    European heart journal, 1987, Volume: 8 Suppl H

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Electrocardiography; Femal

1987
Nifedipine and metoprolol in suspected unstable angina. Data analysis.
    European heart journal, 1987, Volume: 8 Suppl H

    Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Data Interpretation, Statistical; Doubl

1987
Nifedipine and metoprolol in suspected unstable angina. Planning and conduct.
    European heart journal, 1987, Volume: 8 Suppl H

    Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Comb

1987
Nifedipine and metoprolol in suspected unstable angina. Treatment, observations, and outcome events.
    European heart journal, 1987, Volume: 8 Suppl H

    Topics: Adult; Aged; Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Double-Blind Method; Drug

1987
Influence of nifedipine on left ventricular perfusion and function in patients with unstable angina: evaluation with radionuclide techniques.
    European journal of nuclear medicine, 1986, Volume: 11, Issue:11

    Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Circulation; Double-Blind Meth

1986
Left ventricular performance in unstable angina: assessment with radionuclide techniques.
    International journal of cardiology, 1985, Volume: 8, Issue:3

    Topics: Angina Pectoris; Angina, Unstable; Clinical Trials as Topic; Coronary Angiography; Coronary Disease;

1985

Other Studies

5 other studies available for metoprolol and Angina at Rest

ArticleYear
Treatment of unstable angina with emphasis on calcium antagonists.
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:11

    Topics: Angina Pectoris; Angina, Unstable; Anticoagulants; Coronary Circulation; Coronary Disease; Electroca

1984
[Drug therapy of angina pectoris. Are the possibilities exploited well enough?].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1995, Aug-10, Volume: 115, Issue:18

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Angina, Unstable; Female; Humans; Isosorb

1995
The relative bioavailability of metoprolol following oral and rectal administration to volunteers and patients.
    Pharmacy world & science : PWS, 1999, Volume: 21, Issue:5

    Topics: Administration, Oral; Administration, Rectal; Adrenergic beta-Antagonists; Adult; Angina, Unstable;

1999
Myocardial metabolic and hemodynamic effects of a sustained intravenous infusion of nifedipine with and without metoprolol in patients with unstable angina.
    American heart journal, 1991, Volume: 121, Issue:1 Pt 1

    Topics: Adult; Aged; Angina, Unstable; Coronary Circulation; Drug Therapy, Combination; Fatty Acids, Noneste

1991
Serum potassium values in relation to the use of diuretics in patients with unstable angina pectoris.
    European heart journal, 1988, Volume: 9, Issue:7

    Topics: Angina Pectoris; Angina, Unstable; Coronary Disease; Diuretics; Female; Humans; Hypokalemia; Male; M

1988