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metoprolol and Anesthesia

metoprolol has been researched along with Anesthesia in 22 studies

Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.

Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.

Research Excerpts

ExcerptRelevanceReference
"In the present study, we evaluated the antiarrhythmic interaction (s) of metoprolol and lidocaine in 16 dogs using the ventricular fibrillation threshold (VFT) method."7.67Interaction of metoprolol and lidocaine on the ventricular fibrillation threshold in the anesthetized dog. ( Balke, CW; de Langen, CD; Levine, JH; Moore, EN; Spear, JF, 1988)
" In the present study, we investigated the effect of a single bolus administration of L-NAME on blood pressure and heart rate monitored for one hour in anesthetized rats and the influence of vagotomy and beta1-receptor blocker metoprolol on the L-NAME induced bradycardia."3.71Inhibition of beta-1 receptor but not vagotomy can abolish the L-NAME evoked bradycardia in anesthetized rat. ( Bartha, J; Hably, C; Vág, J, 2002)
" Chloralose anesthesia was used to induce sympathetic activation and the presence of intracellular IgG as a criterion of endothelial cell injury."3.68Experimental sympathetic activation causes endothelial injury in the rabbit thoracic aorta via beta 1-adrenoceptor activation. ( Bejne, B; Björk, H; Bondjers, G; Pettersson, K; Strawn, WB, 1990)
"In the present study, we evaluated the antiarrhythmic interaction (s) of metoprolol and lidocaine in 16 dogs using the ventricular fibrillation threshold (VFT) method."3.67Interaction of metoprolol and lidocaine on the ventricular fibrillation threshold in the anesthetized dog. ( Balke, CW; de Langen, CD; Levine, JH; Moore, EN; Spear, JF, 1988)
"35%) anesthesia, the arrhythmogenic dose of epinephrine (ADE) was repeatedly determined before and after prazosin (alpha 1 antagonist; 0."3.67Alterations in the arrhythmogenic dose of epinephrine after adrenergic receptor blockade with prazosin, metoprolol, or yohimbine in halothane-xylazine-anesthetized dogs. ( Benson, GJ; Thurmon, JC; Tranquilli, WJ, 1986)
" Also, the absolute bioavailability from the anaesthetised buccal tablet pH 8."1.40Conscious and anaesthetised Göttingen mini-pigs as an in-vivo model for buccal absorption - pH-dependent absorption of metoprolol from bioadhesive tablets. ( Andersen, MB; Garmer, M; Holm, R; Jacobsen, J; Jespersen, ML; Jørgensen, EB; Karlsson, JJ; Meng-Lund, E, 2014)
"Clevidipine is an ultrashort-acting, intravenous calcium channel antagonist."1.37Clevidipine for controlled hypotension during spinal surgery in adolescents. ( Hoernschemeyer, DG; Tobias, JD, 2011)
"Pheochromocytomas are functionally active, catecholamine-secreting tumours of chromaffin tissue."1.30[Intraoperative diagnosis of a multilocal pheochromocytoma]. ( Egelhof, J; Engelhardt, D; Fürst, H; Welte, M, 1997)
" What remains to be solved is the dosage level."1.26Clinical experiences with prenalterol as an antidote to Beta-adrenoceptor blockade. ( Kulling, P, 1982)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199010 (45.45)18.7374
1990's4 (18.18)18.2507
2000's3 (13.64)29.6817
2010's5 (22.73)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erbas, O1
Yilmaz, M1
Furuichi, Y1
Sakamoto, A1
Meng-Lund, E1
Jacobsen, J1
Andersen, MB1
Jespersen, ML1
Karlsson, JJ1
Garmer, M1
Jørgensen, EB1
Holm, R1
Oksanen, T1
Hynynen, M1
Mizogami, M1
Takakura, K1
Tsuchiya, H1
Tobias, JD1
Hoernschemeyer, DG1
Vág, J1
Hably, C1
Bartha, J1
Ghosh, I1
Bithal, PK1
Dash, HH1
Chaturvedi, A1
Prabhakar, H1
Boucher, M1
Dubray, C1
Duchene-Marullaz, P1
Kopp, U1
Aurell, M1
Svensson, L1
Ablad, B1
Kulling, P1
Maze, M1
Smith, CM1
Welter, J1
Fuchs, HJ1
Herden, HN1
Egelhof, J1
Fürst, H1
Engelhardt, D1
Welte, M1
Lundgren, B1
Carlsson, E1
Herrmann, I1
McFalls, EO1
Duncker, DJ1
Sassen, LM1
Gho, BC1
Verdouw, PD1
Wahlund, G1
Nerme, V1
Abrahamsson, T1
Sjöquist, PO1
Pettersson, K1
Bejne, B1
Björk, H1
Strawn, WB1
Bondjers, G1
de Langen, CD1
Balke, CW1
Spear, JF1
Levine, JH1
Moore, EN1
Tranquilli, WJ2
Thurmon, JC2
Benson, GJ2
Gerritse, R1
Reuwer, PJ1
Pinas, IM1
Beijer, HJ1
Charbon, GA1
Haspels, AA1

Reviews

1 review available for metoprolol and Anesthesia

ArticleYear
[Perioperative cardiovascular evaluation and management for noncardiac surgery].
    Masui. The Japanese journal of anesthesiology, 2014, Volume: 63, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Atenolol; Bisoprolol; Fatty Acids, Monounsaturated; Fluvast

2014

Trials

1 trial available for metoprolol and Anesthesia

ArticleYear
Both clonidine and metoprolol modify anesthetic depth indicators and reduce intraoperative propofol requirement.
    Journal of anesthesia, 2008, Volume: 22, Issue:2

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Anesthesia; Anesthesia, Intravenous;

2008

Other Studies

20 other studies available for metoprolol and Anesthesia

ArticleYear
Metoprolol and diltiazem ameliorate ziprasidone-induced prolonged corrected QT interval in rats.
    Toxicology and industrial health, 2015, Volume: 31, Issue:12

    Topics: Adrenergic beta-1 Receptor Antagonists; Anesthesia; Animals; Anti-Arrhythmia Agents; Antipsychotic A

2015
Conscious and anaesthetised Göttingen mini-pigs as an in-vivo model for buccal absorption - pH-dependent absorption of metoprolol from bioadhesive tablets.
    Drug development and industrial pharmacy, 2014, Volume: 40, Issue:5

    Topics: Adhesives; Anesthesia; Animals; Biological Availability; Chemistry, Pharmaceutical; Consciousness; C

2014
Perioperative beta-blockade: time to change the paradigm?
    Acta anaesthesiologica Scandinavica, 2009, Volume: 53, Issue:5

    Topics: Adrenergic beta-Antagonists; American Hospital Association; Anesthesia; Clinical Protocols; Guidelin

2009
The interactivities with lipid membranes differentially characterize selective and nonselective beta1-blockers.
    European journal of anaesthesiology, 2010, Volume: 27, Issue:9

    Topics: Adrenergic beta-Antagonists; Alprenolol; Anesthesia; Anesthetics; Atenolol; Biomimetics; Lipid Bilay

2010
Clevidipine for controlled hypotension during spinal surgery in adolescents.
    Journal of neurosurgical anesthesiology, 2011, Volume: 23, Issue:4

    Topics: Adolescent; Anesthesia; Anti-Arrhythmia Agents; Antihypertensive Agents; Blood Pressure; Calcium Cha

2011
Inhibition of beta-1 receptor but not vagotomy can abolish the L-NAME evoked bradycardia in anesthetized rat.
    Physiological research, 2002, Volume: 51, Issue:3

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pres

2002
Pharmacological evidence for differences in the beta-adrenoreceptor populations mediating atrial and ventricular chronotropic responses in the unanaesthetized dog.
    Journal of autonomic pharmacology, 1984, Volume: 4, Issue:4

    Topics: Alprenolol; Anesthesia; Animals; Dogs; Electrocardiography; Female; Heart Rate; Isoproterenol; Male;

1984
Effect of prenalterol, a beta-1-adrenoceptor agonist, on renin secretion rate in the anaesthetized dog.
    Acta pharmacologica et toxicologica, 1981, Volume: 49, Issue:3

    Topics: Adrenergic beta-Agonists; Anesthesia; Animals; Denervation; Dogs; Female; Kidney; Male; Metoprolol;

1981
Clinical experiences with prenalterol as an antidote to Beta-adrenoceptor blockade.
    Acta medica Scandinavica. Supplementum, 1982, Volume: 659

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Anesthesia; Cardiac Catheterizat

1982
Identification of receptor mechanism mediating epinephrine-induced arrhythmias during halothane anesthesia in the dog.
    Anesthesiology, 1983, Volume: 59, Issue:4

    Topics: Adrenergic alpha-Antagonists; Anesthesia; Animals; Arrhythmias, Cardiac; Dogs; Epinephrine; Halothan

1983
[Controlled hypotension with metoprolol and sodium nitroprusside].
    Der Anaesthesist, 1983, Volume: 32, Issue:1

    Topics: Adult; Aged; Anesthesia; Blood Pressure; Cardiac Output; Ferricyanides; Heart Rate; Humans; Hypotens

1983
[Intraoperative diagnosis of a multilocal pheochromocytoma].
    Der Anaesthesist, 1997, Volume: 46, Issue:9

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Anesthesia

1997
Beta-adrenoceptor blockade by atenolol, metoprolol and propranolol in the anaesthetized cat.
    European journal of pharmacology, 1979, May-01, Volume: 55, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Atenolol; Cats; Female; Heart Rate; Hemodynamics;

1979
Effect of antiischemic therapy on coronary flow reserve and the pressure-maximal coronary flow relationship in anesthetized swine.
    Journal of cardiovascular pharmacology, 1991, Volume: 18, Issue:6

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Benzeneacetamides; Blood Pressure; Coronary Circul

1991
The beta 1- and beta 2-adrenoceptor affinity and beta 1-blocking potency of S- and R-metoprolol.
    British journal of pharmacology, 1990, Volume: 99, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Cats; Depression, Chemical; Guinea Pigs; Heart; In

1990
Experimental sympathetic activation causes endothelial injury in the rabbit thoracic aorta via beta 1-adrenoceptor activation.
    Circulation research, 1990, Volume: 67, Issue:4

    Topics: Anesthesia; Animals; Aorta, Thoracic; Arteriosclerosis; Blood Pressure; Cell Survival; Chloralose; E

1990
Interaction of metoprolol and lidocaine on the ventricular fibrillation threshold in the anesthetized dog.
    Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:6

    Topics: Anesthesia; Animals; Dogs; Drug Synergism; Electrocardiography; Half-Life; Lidocaine; Metoprolol; Ti

1988
Halothane-catecholamine arrhythmias in swine (Sus scrofa).
    American journal of veterinary research, 1986, Volume: 47, Issue:10

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Blood Pressure; Epinephrine; Female; Halothane; Heart Rat

1986
Alterations in the arrhythmogenic dose of epinephrine after adrenergic receptor blockade with prazosin, metoprolol, or yohimbine in halothane-xylazine-anesthetized dogs.
    American journal of veterinary research, 1986, Volume: 47, Issue:1

    Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Dogs; Dose-Response Relationship, Drug; Epinephrine; Fema

1986
Cardiovascular effects of ritodrine are blocked by metoprolol in the anesthetized dog.
    Archives internationales de pharmacodynamie et de therapie, 1985, Volume: 278, Issue:1

    Topics: Anesthesia; Animals; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Fe

1985