metoprolol has been researched along with Acute Coronary Syndrome in 17 studies
Metoprolol: A selective adrenergic beta-1 blocking agent that is commonly used to treat ANGINA PECTORIS; HYPERTENSION; and CARDIAC ARRHYTHMIAS.
metoprolol : A propanolamine that is 1-(propan-2-ylamino)propan-2-ol substituted by a 4-(2-methoxyethyl)phenoxy group at position 1.
Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum gamma-glutamyltransferase (GGT) and uric acid levels measured in patients with acute coronary syndrome without ST segment elevation (NSTEMI) are important in diagnosis and in predicting the prognosis of the disease." | 9.22 | Comparison of the effects of metoprolol or carvedilol on serum gamma-glutamyltransferase and uric acid levels among patients with acute coronary syndrome without ST segment elevation. ( Aşkın, L; Değirmenci, H; Demirelli, S; Karakelleoğlu, Ş; Lazoğlu, Z; Şimşek, Z; Taş, MH; Topçu, S, 2016) |
| "This study aims to investigate the different clinically relevant allele variants (allele frequencies) of CYP2D6 gene and to determine whether a specific genotype of CYP2D6 gene (based on genetic polymorphism "allelic types" and combination) have impact on metoprolol effectiveness (clinical outcome) in patients who have acute coronary syndrome (ACS)." | 7.91 | Correlation of CYP2D6 allelic polymorphism to outcome of acute coronary syndrome in mid-Euphrates Iraqi patients on metoprolol therapy. ( Al-Aubaidy, HA; Hadi, NR; Mohammad, BI; Swadi, AA, 2019) |
| "Patients with acute coronary syndrome and elevated ST segment in the pre-hospital phase were treated with metoprolol succinate (MS) and thrombolytic therapy." | 7.79 | [Experience in the pre-hospital treatment of acute coronary syndrome with metoprolol succinate]. ( Fedorov, AI; Morozov, SN; Vertkin, AL, 2013) |
| " Based on the Chinese and International guidelines and the Chinese clinical practice, we are conducting this study (NCT03413410) to test the feasibility and tolerability of the metoprolol optimal dosing pathway by observing the percentage of patients achieving target dose in Chinese acute coronary syndrome (ACS) patients during hospitalisation." | 6.90 | Impact of metoprolol standard dosing pathway in Chinese patients with acute coronary syndrome: protocol for a multicentre prospective study. ( Chen, Y; Dong, W; Li, D; Liu, Y; Mu, Y; Wang, J; Zhou, H; Zhou, S, 2019) |
| "Metabolic, hemodynamic, and electrophysiological parameters were studied in all the patients on hospital stay days I and S." | 5.36 | [Efficacy of ivabradine in combination therapy for complicated acute coronary syndrome in patients with type 2 diabetes mellitus]. ( Dolgikh, VT; Kondrat'ev, AI; Stotskiĭ, AO, 2010) |
| " Based on the Chinese and International guidelines and the Chinese clinical practice, we are conducting this study (NCT03413410) to test the feasibility and tolerability of the metoprolol optimal dosing pathway by observing the percentage of patients achieving target dose in Chinese acute coronary syndrome (ACS) patients during hospitalisation." | 2.90 | Impact of metoprolol standard dosing pathway in Chinese patients with acute coronary syndrome: protocol for a multicentre prospective study. ( Chen, Y; Dong, W; Li, D; Liu, Y; Mu, Y; Wang, J; Zhou, H; Zhou, S, 2019) |
| "Metabolic, hemodynamic, and electrophysiological parameters were studied in all the patients on hospital stay days I and S." | 1.36 | [Efficacy of ivabradine in combination therapy for complicated acute coronary syndrome in patients with type 2 diabetes mellitus]. ( Dolgikh, VT; Kondrat'ev, AI; Stotskiĭ, AO, 2010) |
| " Admission daily doses of metoprolol averaged 58 mg compared to discharge daily doses of 88 mg; only 52% of patients had dosage increases." | 1.35 | Use of beta-blockers and effects on heart rate and blood pressure post-acute coronary syndromes: are we on target? ( Donovan, J; Goldberg, RJ; Gore, JM; Herman, M; McKenna, B; Tighe, DA; Tran, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 13 (76.47) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Almengló, C | 1 |
| Couselo-Seijas, M | 1 |
| Agra, RM | 1 |
| Varela-Román, A | 1 |
| García-Acuña, JM | 1 |
| González-Peteiro, M | 1 |
| González-Juanatey, JR | 1 |
| Eiras, S | 1 |
| Álvarez, E | 1 |
| Li, D | 1 |
| Dong, W | 1 |
| Liu, Y | 1 |
| Wang, J | 2 |
| Mu, Y | 1 |
| Zhou, H | 1 |
| Zhou, S | 1 |
| Chen, Y | 1 |
| Ilardi, F | 1 |
| Gargiulo, G | 1 |
| Schiattarella, GG | 1 |
| Giugliano, G | 1 |
| Paolillo, R | 1 |
| Menafra, G | 1 |
| De Angelis, E | 1 |
| Scudiero, L | 1 |
| Franzone, A | 1 |
| Stabile, E | 1 |
| Perrino, C | 1 |
| Cirillo, P | 1 |
| Morisco, C | 1 |
| Izzo, R | 1 |
| Trimarco, V | 1 |
| Esposito, G | 1 |
| Pham, D | 1 |
| Addison, D | 1 |
| Kayani, W | 1 |
| Misra, A | 1 |
| Jneid, H | 1 |
| Resar, J | 1 |
| Lakkis, N | 1 |
| Alam, M | 1 |
| Swadi, AA | 1 |
| Mohammad, BI | 1 |
| Hadi, NR | 1 |
| Al-Aubaidy, HA | 1 |
| Vertkin, AL | 1 |
| Morozov, SN | 1 |
| Fedorov, AI | 1 |
| Maggioni, AP | 1 |
| Aşkın, L | 1 |
| Karakelleoğlu, Ş | 1 |
| Değirmenci, H | 1 |
| Demirelli, S | 1 |
| Şimşek, Z | 1 |
| Taş, MH | 1 |
| Topçu, S | 1 |
| Lazoğlu, Z | 1 |
| Wonnacott, D | 1 |
| Berringer, R | 1 |
| Akay, S | 1 |
| Ozdemir, M | 1 |
| Herman, M | 1 |
| Donovan, J | 1 |
| Tran, M | 1 |
| McKenna, B | 1 |
| Gore, JM | 1 |
| Goldberg, RJ | 1 |
| Tighe, DA | 1 |
| Zedigh, C | 1 |
| Alho, A | 1 |
| Hammar, E | 1 |
| Karlsson, T | 1 |
| Kellerth, T | 1 |
| Svensson, L | 1 |
| Grimbrandt, E | 1 |
| Herlitz, J | 1 |
| Kondrat'ev, AI | 1 |
| Dolgikh, VT | 1 |
| Stotskiĭ, AO | 1 |
| Edwards, J | 1 |
| Goodman, SG | 1 |
| Yan, RT | 1 |
| Welsh, RC | 1 |
| Kornder, JM | 1 |
| Deyoung, JP | 1 |
| Chauret, D | 1 |
| Picard, JP | 1 |
| Eagle, KA | 1 |
| Yan, AT | 1 |
| Irani, F | 1 |
| Herial, N | 1 |
| Colyer, WR | 1 |
| Sisakian, AS | 1 |
| Davtian, AR | 1 |
| Pepoian, SK | 1 |
| Oganesian, AS | 1 |
| Simões, MV | 1 |
| Marin-Neto, JA | 1 |
| Romano, MM | 1 |
| O'Connell, JL | 1 |
| de Santi, GL | 1 |
| Maciel, BC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Center Study on the Metoprolol Optimal Dosing Pathway of Metoprolol Application in Chinese Patients With Acute Coronary Syndrome[NCT03413410] | 1,000 participants (Anticipated) | Interventional | 2018-02-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for metoprolol and Acute Coronary Syndrome
| Article | Year |
|---|---|
Outcomes of beta blocker use in cocaine-associated chest pain: a meta-analysis.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Carvedilol; Cocaine; Hum | 2018 |
Spontaneous coronary artery dissection: Case report and review of the literature.
Topics: Acute Coronary Syndrome; Adrenergic beta-1 Receptor Antagonists; Adult; Aspirin; Atorvastatin; Clopi | 2016 |
4 trials available for metoprolol and Acute Coronary Syndrome
| Article | Year |
|---|---|
Impact of metoprolol standard dosing pathway in Chinese patients with acute coronary syndrome: protocol for a multicentre prospective study.
Topics: Acute Coronary Syndrome; Adrenergic beta-1 Receptor Antagonists; Blood Pressure; China; Dose-Respons | 2019 |
Comparison of the effects of metoprolol or carvedilol on serum gamma-glutamyltransferase and uric acid levels among patients with acute coronary syndrome without ST segment elevation.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Carbazoles; Carvedilol; Female; gamma-Gl | 2016 |
Aspects on the intensity and the relief of pain in the prehospital phase of acute coronary syndrome: experiences from a randomized clinical trial.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Analgesia; Analgesics | 2010 |
[The influence of beta-adrenoblocking therapy on the markers of systemic inflammation in patients with acute coronary syndrome].
Topics: Acute Coronary Syndrome; Adrenergic beta-1 Receptor Antagonists; Aged; Biomarkers; C-Reactive Protei | 2011 |
11 other studies available for metoprolol and Acute Coronary Syndrome
| Article | Year |
|---|---|
Soluble angiotensin-converting enzyme levels in heart failure or acute coronary syndrome: revisiting its modulation and prognosis value.
Topics: Acute Coronary Syndrome; ADAM17 Protein; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angio | 2021 |
Effects of Carvedilol Versus Metoprolol on Platelet Aggregation in Patients With Acute Coronary Syndrome: The PLATE-BLOCK Study.
Topics: Acute Coronary Syndrome; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-1 Receptor Antagon | 2018 |
Correlation of CYP2D6 allelic polymorphism to outcome of acute coronary syndrome in mid-Euphrates Iraqi patients on metoprolol therapy.
Topics: Acute Coronary Syndrome; Adult; Anti-Arrhythmia Agents; Case-Control Studies; Chromatography, High P | 2019 |
[Experience in the pre-hospital treatment of acute coronary syndrome with metoprolol succinate].
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Drug Therapy, Combination; Emergency Med | 2013 |
[Multination clinical trials: what is the relevance and what are the lessons from across-country differences?].
Topics: Acute Coronary Syndrome; Adenosine; Americas; Benzazepines; Cardiovascular Agents; Cardiovascular Di | 2014 |
Acute coronary syndrome presenting after pseudoephedrine use and regression with beta-blocker therapy.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Chest Pain; Coronary Angiography; Electrocardi | 2008 |
Use of beta-blockers and effects on heart rate and blood pressure post-acute coronary syndromes: are we on target?
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Blood Pressure; Dose-Response Relationsh | 2009 |
[Efficacy of ivabradine in combination therapy for complicated acute coronary syndrome in patients with type 2 diabetes mellitus].
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Adult; Benzazepines; Diabetes Mellitus, Type 2 | 2010 |
Has the ClOpidogrel and Metoprolol in Myocardial Infarction Trial (COMMIT) of early β-blocker use in acute coronary syndromes impacted on clinical practice in Canada? Insights from the Global Registry of Acute Coronary Events (GRACE).
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Canada; Clopidogrel; | 2011 |
Impact of an acute coronary syndrome pathway in achieving target heart rate and utilization of evidence-based doses of beta-blockers.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; American Heart | 2012 |
Transient left ventricular dysfunction due to stress-induced cardiomyopathy.
Topics: Acute Coronary Syndrome; Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; | 2007 |