metoprine has been researched along with Neoplasms in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alberto, P; Brugarolas, A; Cavalli, F; Hansen, HH; Klepp, O; Renard, J | 1 |
| de Jager, R; Dorlet, C; Dupont, D; Lagrange, G; Rodzynek, JJ | 1 |
| Brugarolas, A; de Jager, R; Hansen, M | 1 |
| Hill, BT; Price, LA | 1 |
| Bustamante, A; Henderson, GB; Patel, R; Rideout, DC | 1 |
| Goldie, JH; Hill, BT; Price, LA | 2 |
| Alberto, P; Beretta-Piccoli, M; Medenica, R; Peytremann, R | 1 |
| Friedlander, ML; Slowiaczek, P; Tattersall, MH; Taylor, IW | 1 |
1 trial(s) available for metoprine and Neoplasms
| Article | Year |
|---|---|
Initial clinical experience with a simultaneous combination of 2,4-diamino-5(3',4'-dichlorophenyl)-6-methylpyrimidine (DDMP) with folinic acid.
Topics: Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Middle Aged; Neoplasms; Pyrimethamine | 1978 |
8 other study(ies) available for metoprine and Neoplasms
| Article | Year |
|---|---|
Phase II study of diamino-dichlorophenyl-methylpyrimidine (DDMP) with folinic acid (CF) protection and rescue.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Child; Drug Evaluation; Drug Therapy, Combination; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leucovorin; Leukocyte Count; Melanoma; Neoplasms; Platelet Count; Pyrimethamine; Sarcoma | 1980 |
Phase I clinical trial and pharmacology of 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine (metoprine) (DDMP) and folinic acid (CF).
Topics: Antineoplastic Agents; Drug Evaluation; Humans; Kinetics; Leucovorin; Neoplasms; Protein Binding; Pyrimethamine | 1981 |
Phase II clinical trial of DDMP (2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine) and folinic acid (CF) in solid tumors.
Topics: Antineoplastic Agents; Bone Marrow Diseases; Drug Evaluation; Humans; Leucovorin; Neoplasms; Pyrimethamine | 1981 |
An experimentally designed high dose simultaneous combination of a diaminopyrimidine and folinic acid for the treatment of human malignancies.
Topics: Antineoplastic Agents; Bone Marrow Diseases; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leucovorin; Neoplasms; Pyrimethamine | 1981 |
Suramin sodium: pronounced effects on methotrexate transport and anti-folate activity in cultured tumor cells.
Topics: Antineoplastic Agents; Biological Transport; Carrier Proteins; Cell Division; Drug Synergism; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms; Pyrimethamine; Receptors, Cell Surface; Suramin; Tumor Cells, Cultured | 1995 |
Methodichlorophen as anti-tumor drug.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Bone Marrow Diseases; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chlorobenzenes; Drug Therapy, Combination; Erythema; Headache; Humans; Kidney Neoplasms; Leucovorin; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Middle Aged; Neoplasms; Pyrimethamine; Pyrimidines; Teratoma; Testicular Neoplasms | 1975 |
DDMP and selective folinic acid protection in the treatment of malignant disease: a further report.
Topics: Bone Marrow; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Neoplasms; Pyrimethamine; Remission, Spontaneous | 1977 |
Selective toxicity of a new lipophilic antifolate, BW301U, for methotrexate-resistant cells with reduced drug uptake.
Topics: Antineoplastic Agents; Cell Line; Drug Resistance; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms; Pyrimethamine; Pyrimidines | 1985 |