Page last updated: 2024-08-22

metoprine and Neoplasms

metoprine has been researched along with Neoplasms in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alberto, P; Brugarolas, A; Cavalli, F; Hansen, HH; Klepp, O; Renard, J1
de Jager, R; Dorlet, C; Dupont, D; Lagrange, G; Rodzynek, JJ1
Brugarolas, A; de Jager, R; Hansen, M1
Hill, BT; Price, LA1
Bustamante, A; Henderson, GB; Patel, R; Rideout, DC1
Goldie, JH; Hill, BT; Price, LA2
Alberto, P; Beretta-Piccoli, M; Medenica, R; Peytremann, R1
Friedlander, ML; Slowiaczek, P; Tattersall, MH; Taylor, IW1

Trials

1 trial(s) available for metoprine and Neoplasms

ArticleYear
Initial clinical experience with a simultaneous combination of 2,4-diamino-5(3',4'-dichlorophenyl)-6-methylpyrimidine (DDMP) with folinic acid.
    Cancer chemotherapy and pharmacology, 1978, Volume: 1, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Middle Aged; Neoplasms; Pyrimethamine

1978

Other Studies

8 other study(ies) available for metoprine and Neoplasms

ArticleYear
Phase II study of diamino-dichlorophenyl-methylpyrimidine (DDMP) with folinic acid (CF) protection and rescue.
    European journal of cancer, 1980, Volume: 16, Issue:9

    Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Child; Drug Evaluation; Drug Therapy, Combination; Folic Acid Antagonists; Head and Neck Neoplasms; Humans; Leucovorin; Leukocyte Count; Melanoma; Neoplasms; Platelet Count; Pyrimethamine; Sarcoma

1980
Phase I clinical trial and pharmacology of 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine (metoprine) (DDMP) and folinic acid (CF).
    Cancer chemotherapy and pharmacology, 1981, Volume: 6, Issue:1

    Topics: Antineoplastic Agents; Drug Evaluation; Humans; Kinetics; Leucovorin; Neoplasms; Protein Binding; Pyrimethamine

1981
Phase II clinical trial of DDMP (2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine) and folinic acid (CF) in solid tumors.
    Cancer chemotherapy and pharmacology, 1981, Volume: 6, Issue:1

    Topics: Antineoplastic Agents; Bone Marrow Diseases; Drug Evaluation; Humans; Leucovorin; Neoplasms; Pyrimethamine

1981
An experimentally designed high dose simultaneous combination of a diaminopyrimidine and folinic acid for the treatment of human malignancies.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:8

    Topics: Antineoplastic Agents; Bone Marrow Diseases; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leucovorin; Neoplasms; Pyrimethamine

1981
Suramin sodium: pronounced effects on methotrexate transport and anti-folate activity in cultured tumor cells.
    International journal of cancer, 1995, Jun-09, Volume: 61, Issue:6

    Topics: Antineoplastic Agents; Biological Transport; Carrier Proteins; Cell Division; Drug Synergism; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms; Pyrimethamine; Receptors, Cell Surface; Suramin; Tumor Cells, Cultured

1995
Methodichlorophen as anti-tumor drug.
    British medical journal, 1975, Apr-05, Volume: 2, Issue:5961

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Bone Marrow Diseases; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chlorobenzenes; Drug Therapy, Combination; Erythema; Headache; Humans; Kidney Neoplasms; Leucovorin; Leukemia, Myeloid, Acute; Lung Neoplasms; Male; Middle Aged; Neoplasms; Pyrimethamine; Pyrimidines; Teratoma; Testicular Neoplasms

1975
DDMP and selective folinic acid protection in the treatment of malignant disease: a further report.
    Clinical oncology, 1977, Volume: 3, Issue:3

    Topics: Bone Marrow; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Neoplasms; Pyrimethamine; Remission, Spontaneous

1977
Selective toxicity of a new lipophilic antifolate, BW301U, for methotrexate-resistant cells with reduced drug uptake.
    Cancer research, 1985, Volume: 45, Issue:3

    Topics: Antineoplastic Agents; Cell Line; Drug Resistance; Folic Acid Antagonists; Humans; Methotrexate; Neoplasms; Pyrimethamine; Pyrimidines

1985