metoprine has been researched along with Leukemia L 1210 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hansch, C; Khwaja, TA; Selassie, CD | 1 |
| Browman, GP; Calvert, AH; Harrap, KR; Hart, LI; Taylor, GA | 1 |
| Goutas, LJ; Kelleher, LE; Moccio, DM; Montgomery, JA; Sirotnak, FM | 1 |
| Abelson, HT; Browman, GP; Gorka, C; Lazarus, H; Mehta, C | 1 |
| Mitsugi, K; Roy, K; Shane, B; Sirlin, S; Sirotnak, FM | 1 |
| Scheulen, ME | 1 |
| Mines, LS; Sirotnak, FM; Yang, CH | 1 |
1 review(s) available for metoprine and Leukemia L 1210
| Article | Year |
|---|---|
Development of drug derivatives without cross-resistance to parent compounds.
Topics: Animals; Antineoplastic Agents; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Glutathione; Humans; Leukemia L1210; Methotrexate; Pyrimethamine; Tumor Cells, Cultured | 1990 |
6 other study(ies) available for metoprine and Leukemia L 1210
| Article | Year |
|---|---|
Structure-activity relationships of antineoplastic agents in multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured | 1990 |
The intracellular mechanism of action of metoprine (DDMP).
Topics: Animals; Cell Survival; Cells, Cultured; Deoxyuridine; Dose-Response Relationship, Drug; Drug Resistance; Folic Acid Antagonists; Leucovorin; Leukemia L1210; Methotrexate; Mice; Purines; Pyrimethamine; Pyrimidines; Thymidine | 1980 |
Biochemical correlates of responsiveness and collateral sensitivity of some methotrexate-resistant murine tumors to the lipophilic antifolate, metoprine.
Topics: Animals; Biological Transport; Cell Line; Drug Resistance; Formyltetrahydrofolates; Kinetics; Leukemia L1210; Methotrexate; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Pyrimethamine; Tetrahydrofolate Dehydrogenase | 1982 |
Studies with a 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine (DDMP)-resistant L1210 leukemia cell line without cross-resistance to methotrexate.
Topics: Animals; Antineoplastic Agents; Cell Line; Drug Resistance; Folic Acid Antagonists; Kinetics; Leukemia L1210; Male; Methotrexate; Mice; Pyrimethamine | 1980 |
Different antifolate-resistant L1210 cell variants with either increased or decreased folylpolyglutamate synthetase gene expression at the level of mRNA transcription.
Topics: Amino Acid Sequence; Animals; Drug Resistance; Folic Acid Antagonists; Gene Amplification; Gene Expression; Genetic Variation; Humans; Leukemia L1210; Mice; Molecular Sequence Data; Peptide Synthases; Pyrimethamine; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Further studies on a novel class of genetic variants of the L1210 cell with increased folate analogue transport inward. Transport properties of a new variant, evidence for increased levels of a specific transport protein, and its partial characterization
Topics: Affinity Labels; Aminopterin; Animals; Biological Transport; Carrier Proteins; Cell Division; Cell Membrane; Cholic Acids; Chromatography; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Folate Receptors, GPI-Anchored; Folic Acid; Genetic Variation; Kinetics; Leukemia L1210; Methotrexate; Molecular Weight; Pyrimethamine; Receptors, Cell Surface; Succinimides | 1988 |