metoprine has been researched along with Experimental Leukemia in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Griffin, RJ; Meek, MA; Schwalbe, CH; Stevens, MF | 1 |
| Dias, CB; Hansch, C; Khwaja, TA; Pentecost, S; Selassie, CD | 1 |
| Iland, HJ; Laszlo, J; Sedwick, WD | 1 |
| Goldie, JH; Hill, BT; Price, LA | 1 |
1 review(s) available for metoprine and Experimental Leukemia
| Article | Year |
|---|---|
Overcoming methotrexate resistance by a lipophilic antifolate (BW 301U): from theory to models to practice.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Cell Division; Cell Line; DNA; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia, Experimental; Methotrexate; Mice; Models, Biological; Phenotype; Pyrimethamine; Pyrimidines | 1985 |
3 other study(ies) available for metoprine and Experimental Leukemia
| Article | Year |
|---|---|
Structural studies on bioactive compounds. 8. Synthesis, crystal structure, and biological properties of a new series of 2,4-diamino-5-aryl-6-ethylpyrimidine dihydrofolate reductase inhibitors with in vivo activity against a methotrexate-resistant tumor c
Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Crystallization; Folic Acid Antagonists; Leukemia, Experimental; Liver; Methotrexate; Mice; Molecular Structure; Pyrimidines; Rats; Structure-Activity Relationship; Tumor Cells, Cultured | 1989 |
Comparative structure-activity relationships of antifolate triazines inhibiting murine tumor cells sensitive and resistant to methotrexate.
Topics: Animals; Chemical Phenomena; Chemistry, Physical; Chickens; Drug Resistance; Folic Acid Antagonists; Humans; Leukemia L5178; Leukemia, Experimental; Mathematics; Methotrexate; Mice; Structure-Activity Relationship; Triazines | 1984 |
Studies concerned with overcoming resistance to methotrexate: a comparison of the effects of methotrexate and 2,4-diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine (BW50197) on the colony forming ability of L5178Y cells.
Topics: Animals; Cell Line; Chlorobenzenes; Diamines; Folic Acid; Folic Acid Antagonists; Leukemia, Experimental; Methotrexate; Mice; Pyrimethamine; Pyrimidines | 1973 |