metolazone has been researched along with Symptom Cluster in 4 studies
Metolazone: A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
metolazone : A quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gitelman's syndrome is an autosomal recessive renal tubular disorder characterized by hypokalemic metabolic alkalosis, hypomagnesemia, and hypocalciuria." | 1.31 | Functional expression of mutations in the human NaCl cotransporter: evidence for impaired routing mechanisms in Gitelman's syndrome. ( Bindels, RJ; De Jong, JC; Knoers, NV; Van Den Heuvel, LP; Van Der Vliet, WA; Willems, PH, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Srivastava, S | 1 |
| Kemnic, T | 1 |
| Hildebrandt, KR | 1 |
| Sabath, E | 1 |
| Meade, P | 1 |
| Berkman, J | 1 |
| de los Heros, P | 1 |
| Moreno, E | 1 |
| Bobadilla, NA | 1 |
| Vázquez, N | 1 |
| Ellison, DH | 1 |
| Gamba, G | 1 |
| Arosio, E | 1 |
| Pancera, P | 1 |
| Apolloni, E | 1 |
| Covi, G | 1 |
| Lechi, A | 1 |
| De Jong, JC | 1 |
| Van Der Vliet, WA | 1 |
| Van Den Heuvel, LP | 1 |
| Willems, PH | 1 |
| Knoers, NV | 1 |
| Bindels, RJ | 1 |
4 other studies available for metolazone and Symptom Cluster
| Article | Year |
|---|---|
BRASH syndrome.
Topics: Antihypertensive Agents; Atrioventricular Block; Bradycardia; Bumetanide; Carvedilol; Female; Humans | 2020 |
Pathophysiology of functional mutations of the thiazide-sensitive Na-Cl cotransporter in Gitelman disease.
Topics: Alkalosis; Animals; Carrier Proteins; Diuretics; Dose-Response Relationship, Drug; Female; Humans; H | 2004 |
[Clinical evaluation of metolazone in edematogenic syndromes].
Topics: Adult; Aged; Coronary Disease; Diuretics; Edema; Female; Heart Failure; Heart Valve Diseases; Humans | 1984 |
Functional expression of mutations in the human NaCl cotransporter: evidence for impaired routing mechanisms in Gitelman's syndrome.
Topics: Alkalosis; Animals; Calcium; Carrier Proteins; Female; Glycosylation; Humans; Hypokalemia; Immunohis | 2002 |