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metolazone and Liver Cirrhosis

metolazone has been researched along with Liver Cirrhosis in 4 studies

Metolazone: A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
metolazone : A quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"Eighteen patients with hepatic cirrhosis or nephrotic syndrome and having edema and/or ascites were treated during successive periods with metolazone 5 to 40 mg/day, spironolactone 100 mg/day, and with both diuretics concurrently."9.04Metolazone and spironolactone in cirrhosis and the nephrotic syndrome. ( Arruda, JA; Dhupelia, VB; Kane, RE; Lang, GR; Nascimento, L; Westenfelder, C, 1977)
"Eighteen patients with hepatic cirrhosis or nephrotic syndrome and having edema and/or ascites were treated during successive periods with metolazone 5 to 40 mg/day, spironolactone 100 mg/day, and with both diuretics concurrently."5.04Metolazone and spironolactone in cirrhosis and the nephrotic syndrome. ( Arruda, JA; Dhupelia, VB; Kane, RE; Lang, GR; Nascimento, L; Westenfelder, C, 1977)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arosio, E1
Pancera, P1
Apolloni, E1
Covi, G1
Lechi, A1
Lang, GR1
Westenfelder, C1
Nascimento, L1
Dhupelia, VB1
Arruda, JA1
Kane, RE1
Sheth, UK2
Mehta, JM2
Paul, T2
Nair, S1
Sanghvi, B2
Kshirsagar, NA1
Gupta, KC1
Shah, BP1
Vora, KK1
Acharya, VN1

Trials

1 trial available for metolazone and Liver Cirrhosis

ArticleYear
Metolazone and spironolactone in cirrhosis and the nephrotic syndrome.
    Clinical pharmacology and therapeutics, 1977, Volume: 21, Issue:2

    Topics: Adult; Aged; Blood Cell Count; Blood Glucose; Blood Pressure; Body Weight; Chlorides; Clinical Trial

1977

Other Studies

3 other studies available for metolazone and Liver Cirrhosis

ArticleYear
[Clinical evaluation of metolazone in edematogenic syndromes].
    La Clinica terapeutica, 1984, Dec-15, Volume: 111, Issue:5

    Topics: Adult; Aged; Coronary Disease; Diuretics; Edema; Female; Heart Failure; Heart Valve Diseases; Humans

1984
Clinical experience with metolazone--a new diuretic--in cases of edema and ascites due to hepatic cirrhosis, C.C.F., and malnutrition.
    Journal of postgraduate medicine, 1977, Volume: 23, Issue:4

    Topics: Adult; Diuretics; Edema; Heart Failure; Humans; Liver Cirrhosis; Male; Metolazone; Nutrition Disorde

1977
Effect of metolazone addition on furosemide resistant cases of edema.
    The Journal of the Association of Physicians of India, 1978, Volume: 26, Issue:10

    Topics: Adolescent; Adult; Diuretics; Drug Resistance; Drug Therapy, Combination; Edema; Female; Furosemide;

1978