metolazone has been researched along with Liver Cirrhosis in 4 studies
Metolazone: A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
metolazone : A quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighteen patients with hepatic cirrhosis or nephrotic syndrome and having edema and/or ascites were treated during successive periods with metolazone 5 to 40 mg/day, spironolactone 100 mg/day, and with both diuretics concurrently." | 9.04 | Metolazone and spironolactone in cirrhosis and the nephrotic syndrome. ( Arruda, JA; Dhupelia, VB; Kane, RE; Lang, GR; Nascimento, L; Westenfelder, C, 1977) |
| "Eighteen patients with hepatic cirrhosis or nephrotic syndrome and having edema and/or ascites were treated during successive periods with metolazone 5 to 40 mg/day, spironolactone 100 mg/day, and with both diuretics concurrently." | 5.04 | Metolazone and spironolactone in cirrhosis and the nephrotic syndrome. ( Arruda, JA; Dhupelia, VB; Kane, RE; Lang, GR; Nascimento, L; Westenfelder, C, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arosio, E | 1 |
| Pancera, P | 1 |
| Apolloni, E | 1 |
| Covi, G | 1 |
| Lechi, A | 1 |
| Lang, GR | 1 |
| Westenfelder, C | 1 |
| Nascimento, L | 1 |
| Dhupelia, VB | 1 |
| Arruda, JA | 1 |
| Kane, RE | 1 |
| Sheth, UK | 2 |
| Mehta, JM | 2 |
| Paul, T | 2 |
| Nair, S | 1 |
| Sanghvi, B | 2 |
| Kshirsagar, NA | 1 |
| Gupta, KC | 1 |
| Shah, BP | 1 |
| Vora, KK | 1 |
| Acharya, VN | 1 |
1 trial available for metolazone and Liver Cirrhosis
| Article | Year |
|---|---|
Metolazone and spironolactone in cirrhosis and the nephrotic syndrome.
Topics: Adult; Aged; Blood Cell Count; Blood Glucose; Blood Pressure; Body Weight; Chlorides; Clinical Trial | 1977 |
3 other studies available for metolazone and Liver Cirrhosis
| Article | Year |
|---|---|
[Clinical evaluation of metolazone in edematogenic syndromes].
Topics: Adult; Aged; Coronary Disease; Diuretics; Edema; Female; Heart Failure; Heart Valve Diseases; Humans | 1984 |
Clinical experience with metolazone--a new diuretic--in cases of edema and ascites due to hepatic cirrhosis, C.C.F., and malnutrition.
Topics: Adult; Diuretics; Edema; Heart Failure; Humans; Liver Cirrhosis; Male; Metolazone; Nutrition Disorde | 1977 |
Effect of metolazone addition on furosemide resistant cases of edema.
Topics: Adolescent; Adult; Diuretics; Drug Resistance; Drug Therapy, Combination; Edema; Female; Furosemide; | 1978 |