metolazone has been researched along with Electrolytes in 3 studies
Metolazone: A quinazoline-sulfonamide derived DIURETIC that functions by inhibiting SODIUM CHLORIDE SYMPORTERS.
metolazone : A quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 mg/day of metolazone or 25 mg/day of chlorthalidone are effective antihypertensive agents but that blood pressure lowering may be inconsistent at these dosage levels." | 2.66 | Low-dose diuretic therapy for hypertension. ( Moser, M, 1986) |
| "Metolazone action was studied 1) in vitro on isolated operculum of Fundulus heteroclitus (active chloride transport) using an Ussing chamber (metolazone conc 500 microM) and in vivo 2) using the modified Sperber technique in the hen (metolazone infusion rate 0." | 1.27 | Some effects of metolazone on electrolyte transport. ( Beermann, B; Eriksson, O; Lindström, B; Odlind, B, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reams, GP | 1 |
| Bauer, JH | 1 |
| Odlind, B | 1 |
| Beermann, B | 1 |
| Lindström, B | 1 |
| Eriksson, O | 1 |
| Moser, M | 1 |
1 trial available for metolazone and Electrolytes
| Article | Year |
|---|---|
Low-dose diuretic therapy for hypertension.
Topics: Chlorthalidone; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Electrolytes; Fema | 1986 |
2 other studies available for metolazone and Electrolytes
| Article | Year |
|---|---|
The effect of triple drug therapy on renal function in patients with essential hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Aldosterone; Antihypertensive Agents; Atenolol; Betaxolol; Blood | 1989 |
Some effects of metolazone on electrolyte transport.
Topics: Adult; Animals; Biological Transport, Active; Bufonidae; Chickens; Diuresis; Diuretics; Electrolytes | 1987 |