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metoclopramide and Tourette Syndrome

metoclopramide has been researched along with Tourette Syndrome in 6 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Tourette Syndrome: A neuropsychological disorder related to alterations in DOPAMINE metabolism and neurotransmission involving frontal-subcortical neuronal circuits. Both multiple motor and one or more vocal tics need to be present with TICS occurring many times a day, nearly daily, over a period of more than one year. The onset is before age 18 and the disturbance is not due to direct physiological effects of a substance or another medical condition. The disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning. (From DSM-IV, 1994; Neurol Clin 1997 May;15(2):357-79)

Research Excerpts

ExcerptRelevanceReference
"To investigate the effects of metoclopramide on the intelligence and memory in patients with Tourette syndrome."9.10[Effects of metoclopramide on intelligence and memory in patients with Tourette syndrome]. ( Xie, XL; Ye, HC; You, Y, 2003)
"To investigate the effects of metoclopramide on the intelligence and memory in patients with Tourette syndrome."5.10[Effects of metoclopramide on intelligence and memory in patients with Tourette syndrome]. ( Xie, XL; Ye, HC; You, Y, 2003)
"Metoclopramide was started at 5 mg daily and titrated as needed to a maximum dose of 40 mg daily."2.71A randomized, double-blind, placebo-controlled trial of metoclopramide for the treatment of Tourette's disorder. ( Castellanos, FX; Craven-Thuss, B; McKinlay, BD; Nicolson, R; Smith, J, 2005)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ye, HC1
Xie, XL1
You, Y1
Acosta, MT1
Castellanos, FX2
Nicolson, R1
Craven-Thuss, B1
Smith, J1
McKinlay, BD1
Berlin, CM1
Desai, AB1
Doongaji, DR1
Satoskar, RS1
Smirnov, AIu1

Reviews

1 review available for metoclopramide and Tourette Syndrome

ArticleYear
Advances in pediatric pharmacology and toxicology.
    Advances in pediatrics, 1983, Volume: 30

    Topics: Animals; Anti-Bacterial Agents; Aspirin; Attention Deficit Disorder with Hyperactivity; Biological A

1983

Trials

3 trials available for metoclopramide and Tourette Syndrome

ArticleYear
[Effects of metoclopramide on intelligence and memory in patients with Tourette syndrome].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2003, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Intelligence; Male; Memory; Metocloprami

2003
A randomized, double-blind, placebo-controlled trial of metoclopramide for the treatment of Tourette's disorder.
    Journal of the American Academy of Child and Adolescent Psychiatry, 2005, Volume: 44, Issue:7

    Topics: Adolescent; Child; Chronic Disease; Diagnostic and Statistical Manual of Mental Disorders; Dopamine

2005
[Use of metoclopramide (cerucal) in Tourette syndrome].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1989, Volume: 89, Issue:8

    Topics: Adolescent; Antipsychotic Agents; Child; Clinical Trials as Topic; Female; Humans; Male; Metoclopram

1989

Other Studies

2 other studies available for metoclopramide and Tourette Syndrome

ArticleYear
Use of the "inverse neuroleptic" metoclopramide in Tourette syndrome: an open case series.
    Journal of child and adolescent psychopharmacology, 2004,Spring, Volume: 14, Issue:1

    Topics: Adolescent; Antipsychotic Agents; Child; Humans; Male; Metoclopramide; Middle Aged; Tourette Syndrom

2004
metoclopramide in Gilles de la Tourette's syndrome (a case report).
    Journal of postgraduate medicine, 1983, Volume: 29, Issue:3

    Topics: Adult; Humans; Male; Metoclopramide; Tourette Syndrome

1983