Page last updated: 2024-10-31

metoclopramide and Tardive Dyskinesia

metoclopramide has been researched along with Tardive Dyskinesia in 6 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Tardive Dyskinesia: Drug-related movement disorder characterized by uncontrollable movements in certain muscles. It is associated with a long-term exposure to certain neuroleptic medications (e.g., METOCLOPRAMIDE).

Research Excerpts

ExcerptRelevanceReference
"A PubMed, Google Scholar, and Cross Reference search was done using the key words and combined searches: drug-drug interaction, gastroparesis, metoclopramide, natural history, pharmacokinetics, pharmacodynamics, drug-drug interaction, outcome, risk factors, tardive dyskinesia."9.01Gastroparesis, metoclopramide, and tardive dyskinesia: Risk revisited. ( Al-Saffar, A; Hellström, PM; Lennernäs, H, 2019)
" Food and Drug Administration (FDA) placed a black box warning on metoclopramide (MCP) due to the increased risks and prevalence of tardive dyskinesia (TD)."7.85MSBIS: A Multi-Step Biomedical Informatics Screening Approach for Identifying Medications that Mitigate the Risks of Metoclopramide-Induced Tardive Dyskinesia. ( Caylor, ML; Culbertson, VL; Dang, HK; Economen, PJ; Flynn, ST; Ham, AG; Johnson, RW; Tao, A; Tivis, RD; Xu, D, 2017)
"A PubMed, Google Scholar, and Cross Reference search was done using the key words and combined searches: drug-drug interaction, gastroparesis, metoclopramide, natural history, pharmacokinetics, pharmacodynamics, drug-drug interaction, outcome, risk factors, tardive dyskinesia."5.01Gastroparesis, metoclopramide, and tardive dyskinesia: Risk revisited. ( Al-Saffar, A; Hellström, PM; Lennernäs, H, 2019)
" Submissions related to metoclopramide by far exceeded reports about other agents and mostly described tardive dyskinesia or other neurological concerns."3.85From Harmful Treatment to Secondary Gain: Adverse Event Reporting in Dyspepsia and Gastroparesis. ( Bielefeldt, K, 2017)
" Food and Drug Administration (FDA) placed a black box warning on metoclopramide (MCP) due to the increased risks and prevalence of tardive dyskinesia (TD)."3.85MSBIS: A Multi-Step Biomedical Informatics Screening Approach for Identifying Medications that Mitigate the Risks of Metoclopramide-Induced Tardive Dyskinesia. ( Caylor, ML; Culbertson, VL; Dang, HK; Economen, PJ; Flynn, ST; Ham, AG; Johnson, RW; Tao, A; Tivis, RD; Xu, D, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Lacy, BE1
Cangemi, DJ1
Bielefeldt, K1
Xu, D1
Ham, AG1
Tivis, RD1
Caylor, ML1
Tao, A1
Flynn, ST1
Economen, PJ1
Dang, HK1
Johnson, RW1
Culbertson, VL1
Al-Saffar, A1
Lennernäs, H1
Hellström, PM1
Thomson, AM1
Wallace, J1
Kobylecki, C1
Kass, JS1
Rose, RV1

Reviews

2 reviews available for metoclopramide and Tardive Dyskinesia

ArticleYear
Gastroparesis, metoclopramide, and tardive dyskinesia: Risk revisited.
    Neurogastroenterology and motility, 2019, Volume: 31, Issue:11

    Topics: Antiemetics; Dopamine D2 Receptor Antagonists; Gastroparesis; Humans; Metoclopramide; Risk Factors;

2019
Liability and Failure to Warn a Patient.
    Continuum (Minneapolis, Minn.), 2019, Volume: 25, Issue:4

    Topics: Dopamine D2 Receptor Antagonists; Drug-Related Side Effects and Adverse Reactions; Humans; Liability

2019

Other Studies

4 other studies available for metoclopramide and Tardive Dyskinesia

ArticleYear
Controversies in Gastroparesis: Discussing the Sticky Points.
    The American journal of gastroenterology, 2021, 08-01, Volume: 116, Issue:8

    Topics: Abdominal Pain; Antiemetics; Chronic Disease; Diabetes Complications; Diagnosis, Differential; Diagn

2021
From Harmful Treatment to Secondary Gain: Adverse Event Reporting in Dyspepsia and Gastroparesis.
    Digestive diseases and sciences, 2017, Volume: 62, Issue:11

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Antiemetics; Databases, Factual; Deglutition D

2017
MSBIS: A Multi-Step Biomedical Informatics Screening Approach for Identifying Medications that Mitigate the Risks of Metoclopramide-Induced Tardive Dyskinesia.
    EBioMedicine, 2017, Volume: 26

    Topics: Antipsychotic Agents; Databases, Factual; Drug Interactions; Drug-Related Side Effects and Adverse R

2017
Tardive dyskinesia after drug withdrawal in two older adults: Clinical features, complications and management.
    Geriatrics & gerontology international, 2019, Volume: 19, Issue:6

    Topics: Aged; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Administration Schedule; Female;

2019