Page last updated: 2024-10-31

metoclopramide and Syndrome

metoclopramide has been researched along with Syndrome in 26 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Syndrome: A characteristic symptom complex.

Research Excerpts

ExcerptRelevanceReference
"Patients with cancer frequently report gastrointestinal symptoms such as anorexia, early satiety, nausea, vomiting, and bloating."7.80Long-term safety and clinical effectiveness of controlled-release metoclopramide in cancer-associated dyspepsia syndrome: a multicentre evaluation. ( Chow, W; Darke, A; Harsanyi, Z; Marshall, D; Pearen, S; Plourde, JY; Wilson, J; Yoshida, S, 2002)
"A 4-year-old female blue and gold macaw (Ara ararauna) with a history of chronic vomiting was treated with metoclopramide hydrochloride."7.68Adverse drug reaction to metoclopramide hydrochloride in a macaw with proventricular dilatation syndrome. ( Massey, JG, 1993)
"We have reported the case of a 58-year-old woman with cerebral palsy who experienced a persistent, generalized syndrome of dystonia and rigidity (tardive dystonia-parkinsonism) while being treated for vomiting with metoclopramide in combination with prochlorperazine."7.68Persistent extrapyramidal syndrome with dystonia and rigidity caused by combined metoclopramide and prochlorperazine therapy. ( Factor, SA; Matthews, MK, 1991)
"Patients with cancer frequently report gastrointestinal symptoms such as anorexia, early satiety, nausea, vomiting, and bloating."3.80Long-term safety and clinical effectiveness of controlled-release metoclopramide in cancer-associated dyspepsia syndrome: a multicentre evaluation. ( Chow, W; Darke, A; Harsanyi, Z; Marshall, D; Pearen, S; Plourde, JY; Wilson, J; Yoshida, S, 2002)
"Extrapyramidal syndromes (EPS) are clinically relevant side effects of metoclopramide which are often not anticipated."3.73Acute dystonic reaction to metoclopramide in patients carrying homozygous cytochrome P450 2D6 genetic polymorphisms. ( Sonneveld, P; van der Padt, A; van Schaik, RH, 2006)
" Management of the infant with gastroesophageal reflux disease, in addition to nonpharmacological interventions pharmacologic therapy, including metoclopramide HCl and Fe (6 mg/kg per day, oral) was useful for the patients, and their paroxysmal attacks decreased dramatically (0-2 attacks/day)."3.73Sandifer Syndrome: a continuing problem of misdiagnosis. ( Kabakuş, N; Kurt, A, 2006)
"A 4-year-old female blue and gold macaw (Ara ararauna) with a history of chronic vomiting was treated with metoclopramide hydrochloride."3.68Adverse drug reaction to metoclopramide hydrochloride in a macaw with proventricular dilatation syndrome. ( Massey, JG, 1993)
"We have reported the case of a 58-year-old woman with cerebral palsy who experienced a persistent, generalized syndrome of dystonia and rigidity (tardive dystonia-parkinsonism) while being treated for vomiting with metoclopramide in combination with prochlorperazine."3.68Persistent extrapyramidal syndrome with dystonia and rigidity caused by combined metoclopramide and prochlorperazine therapy. ( Factor, SA; Matthews, MK, 1991)
"Plasma levels of beta-endorphin (beta-EP) and prolactin (PRL) were measured in 5 girls with Rett syndrome and in a control group before and after giving 10 mg metoclopramide i."3.67Plasma endorphins in Rett syndrome: preliminary data. ( Bernasconi, S; Facchinetti, F; Genazzani, AR; Nalin, A; Petraglia, F; Zappella, M, 1986)
"We present extrapyramidal syndrome in 22 children (5 en 1984 and 17 during 1985) who received clebopride (15), metoclopramide (6) and haloperidol (1), almost all at the level of therapeutic doses, which fact seems to indicated a idiosyncratic factor."3.67[Drug-induced extrapyramidal syndrome. Apropos of 22 cases]. ( Calvo Fernández, J; Castro-Gago, M; Couce Pico, M; López Rois, F; Novo, I, 1987)
"Metoclopramide is an effective agent in treating the symptom complex of delayed gastric emptying."2.65Metoclopramide therapy in patients with delayed gastric emptying: a randomized, double-blind study. ( Davidson, ED; Hersh, T; Moore, C; Perkel, MS, 1979)
"Treatment with metoclopramide hydrochloride and bethanechol chloride resulted in improved attitude, appetite, Schirmer tear test response, and decrease in frequency of vomiting within 24 hours."1.28A syndrome resembling feline dysautonomia (Key-Gaskell syndrome) in a dog. ( Lappin, MR; Wise, LA, 1991)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19909 (34.62)18.7374
1990's9 (34.62)18.2507
2000's5 (19.23)29.6817
2010's1 (3.85)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Na, S1
Jung, DE1
Hwang, E1
Kim, T1
Holland, EL1
Saneto, RP1
Knipper, EK1
Bajgoric, S1
Samra, K1
Chandrapalan, S1
Gautam, N1
Wilson, J1
Plourde, JY1
Marshall, D1
Yoshida, S1
Chow, W1
Harsanyi, Z1
Pearen, S1
Darke, A1
van der Padt, A1
van Schaik, RH1
Sonneveld, P1
Stein, MH1
Sorscher, M1
Caroff, SN1
Kabakuş, N1
Kurt, A1
Komorowski, JM1
Reterski, Z1
Owczarczyk, I1
McBeath, JG1
Nanda, A1
Nelson, KA1
Walsh, TD1
Massey, JG1
Nowicki, MJ1
Peterson, RB1
Kropp, S1
Hauser, U1
Emrich, HM1
Grohmann, R1
Perkel, MS1
Moore, C1
Hersh, T1
Davidson, ED1
Corsini, P1
Lepore, R1
Mordini, M1
Quaranta, S1
Bifarini, G2
Favetta, P2
Ciammiti, B1
Cirulli, P1
Del Sindaco, F1
Pasqualucci, A1
Wise, LA1
Lappin, MR1
Factor, SA1
Matthews, MK1
Trabalza, N1
Falconi, S1
Malà, L1
Wood, CD1
Stewart, JJ1
Wood, MJ1
Manno, JE1
Manno, BR1
Mims, ME1
Sato, T1
Igarashi, N1
Minami, S1
Okabe, T1
Hashimoto, H1
Hasui, M1
Kato, E1
Rogers, AI1
Facchinetti, F1
Zappella, M1
Nalin, A1
Petraglia, F1
Bernasconi, S1
Genazzani, AR1
Porias Cuéllas, HL1
Hernández Bueno, JA1
Villanueva, C1
Benavides, S1
Cortés-Gallegos, V1
López Rois, F1
Couce Pico, M1
Calvo Fernández, J1
Novo, I1
Castro-Gago, M1
Haidvogl, M1
Wendler, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622]Phase 23 participants (Actual)Interventional2014-07-31Terminated (stopped due to Lack of recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for metoclopramide and Syndrome

ArticleYear
Cannabinoid hyperemesis syndrome: a guide for the practising clinician.
    BMJ case reports, 2015, Dec-23, Volume: 2015

    Topics: Adult; Antiemetics; Cannabinoids; Cannabis; Disease Management; Dronabinol; Humans; Male; Marijuana

2015
Long-term safety and clinical effectiveness of controlled-release metoclopramide in cancer-associated dyspepsia syndrome: a multicentre evaluation.
    Journal of palliative care, 2002,Summer, Volume: 18, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anorexia; Antiemetics; Delayed-Action Preparat

2002
Dubowitz syndrome and achalasia: two rare conditions in a child.
    Clinical pediatrics, 1998, Volume: 37, Issue:3

    Topics: Adolescent; Anti-Ulcer Agents; Antiemetics; Gastroesophageal Reflux; Humans; Infant, Low Birth Weigh

1998

Trials

6 trials available for metoclopramide and Syndrome

ArticleYear
Long-term safety and clinical effectiveness of controlled-release metoclopramide in cancer-associated dyspepsia syndrome: a multicentre evaluation.
    Journal of palliative care, 2002,Summer, Volume: 18, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anorexia; Antiemetics; Delayed-Action Preparat

2002
Metoclopramide in anorexia caused by cancer-associated dyspepsia syndrome (CADS).
    Journal of palliative care, 1993,Summer, Volume: 9, Issue:2

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anorexia; Dyspepsia; Female; Gastrointestinal

1993
Metoclopramide therapy in patients with delayed gastric emptying: a randomized, double-blind study.
    Digestive diseases and sciences, 1979, Volume: 24, Issue:9

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Gastric Emptying; Humans; Male;

1979
[Pharmacologic prevention of Mendelson syndrome. A controlled clinical trial].
    Minerva anestesiologica, 1992, Volume: 58, Issue:3

    Topics: Adult; Anesthesia, Obstetrical; Cesarean Section; Drug Therapy, Combination; Female; Gastric Acidity

1992
[Possible effects of pharmacologic prophylaxis for Mendelson's syndrome on newborns].
    Minerva anestesiologica, 1990, Volume: 56, Issue:12

    Topics: Analysis of Variance; Blood Gas Analysis; Cesarean Section; Humans; Infant, Newborn; Metoclopramide;

1990
Therapeutic effects of antimotion sickness medications on the secondary symptoms of motion sickness.
    Aviation, space, and environmental medicine, 1990, Volume: 61, Issue:2

    Topics: Adolescent; Adult; Arousal; Caffeine; Dose-Response Relationship, Drug; Drug Therapy, Combination; E

1990

Other Studies

18 other studies available for metoclopramide and Syndrome

ArticleYear
Area postrema syndrome caused by medullary infarction.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2022, Volume: 31, Issue:9

    Topics: Area Postrema; Female; Humans; Infarction; Metoclopramide; Nausea; Ondansetron; Syndrome; Vomiting

2022
Hypermetabolic Syndrome and Dyskinesia After Neurologic Surgery for Labrune Syndrome: A Case Report.
    A&A practice, 2020, Volume: 14, Issue:7

    Topics: Acidosis, Lactic; Adult; Antiemetics; Calcinosis; Central Nervous System Cysts; Dopamine D2 Receptor

2020
Acute dystonic reaction to metoclopramide in patients carrying homozygous cytochrome P450 2D6 genetic polymorphisms.
    The Netherlands journal of medicine, 2006, Volume: 64, Issue:5

    Topics: Acute Disease; Adult; Cytochrome P-450 CYP2D6; Dopamine Antagonists; Dystonia; Female; Humans; Leuke

2006
Neuroleptic malignant syndrome induced by metoclopramide in an infant with Freeman-Sheldon syndrome.
    Anesthesia and analgesia, 2006, Volume: 103, Issue:3

    Topics: Abnormalities, Multiple; Dopamine Antagonists; Female; Humans; Infant; Metoclopramide; Neuroleptic M

2006
Sandifer Syndrome: a continuing problem of misdiagnosis.
    Pediatrics international : official journal of the Japan Pediatric Society, 2006, Volume: 48, Issue:6

    Topics: Anemia, Iron-Deficiency; Bronchial Spasm; Diagnosis, Differential; Diagnostic Errors; Dopamine Antag

2006
Acupuncture therapy does not change metoclopramide-induced prolactin secretion in normoprolactinaemic galactorrhea syndrome.
    Endokrynologia Polska, 1984, Volume: 35, Issue:4

    Topics: Acupuncture Therapy; Adult; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Pregn

1984
Use of dihydroergotamine in patients with postconcussion syndrome.
    Headache, 1994, Volume: 34, Issue:3

    Topics: Adult; Brain Concussion; Dihydroergotamine; Drug Therapy, Combination; Female; Headache; Humans; Mal

1994
Adverse drug reaction to metoclopramide hydrochloride in a macaw with proventricular dilatation syndrome.
    Journal of the American Veterinary Medical Association, 1993, Aug-15, Volume: 203, Issue:4

    Topics: Animals; Bird Diseases; Dilatation, Pathologic; Diphenhydramine; Female; Metoclopramide; Nervous Sys

1993
Metoclopramide-related pisa syndrome in clozapine treatment.
    The Journal of neuropsychiatry and clinical neurosciences, 2001,Summer, Volume: 13, Issue:3

    Topics: Clozapine; Dopamine Antagonists; Dyskinesia, Drug-Induced; Female; Humans; Metoclopramide; Middle Ag

2001
[Studies on the therapy of dyspeptic syndromes using a new pharmacologic combination].
    La Clinica terapeutica, 1976, Aug-15, Volume: 78, Issue:3

    Topics: Adolescent; Adult; Aged; Drug Combinations; Drug Evaluation; Dyspepsia; Ethers; Female; Humans; Male

1976
A syndrome resembling feline dysautonomia (Key-Gaskell syndrome) in a dog.
    Journal of the American Veterinary Medical Association, 1991, Jun-15, Volume: 198, Issue:12

    Topics: Animals; Autonomic Nervous System Diseases; Bethanechol; Bethanechol Compounds; Dog Diseases; Dogs;

1991
Persistent extrapyramidal syndrome with dystonia and rigidity caused by combined metoclopramide and prochlorperazine therapy.
    Southern medical journal, 1991, Volume: 84, Issue:5

    Topics: Basal Ganglia Diseases; Cerebral Palsy; Dystonia; Female; Humans; Intellectual Disability; Metoclopr

1991
Recurrent attacks of vomiting, hypertension and psychotic depression: a syndrome of periodic catecholamine and prostaglandin discharge.
    Acta endocrinologica, 1988, Volume: 117, Issue:2

    Topics: Adolescent; Adrenocorticotropic Hormone; Arginine Vasopressin; Child, Preschool; Clonidine; Dinopros

1988
Gastric emptying disorders.
    Comprehensive therapy, 1985, Volume: 11, Issue:12

    Topics: Bethanechol; Bethanechol Compounds; Domperidone; Food; Gastric Emptying; Gastric Fundus; Humans; Met

1985
Plasma endorphins in Rett syndrome: preliminary data.
    American journal of medical genetics. Supplement, 1986, Volume: 1

    Topics: Adolescent; beta-Endorphin; beta-Lipotropin; Child; Child, Preschool; Endorphins; Female; Humans; In

1986
[The physiopathological aspects of the normoprolactinemic amenorrhea-galactorrhea syndrome].
    Ginecologia y obstetricia de Mexico, 1987, Volume: 55

    Topics: Amenorrhea; Bromocriptine; Female; Galactorrhea; Humans; Hyperprolactinemia; Metoclopramide; Prolact

1987
[Drug-induced extrapyramidal syndrome. Apropos of 22 cases].
    Anales espanoles de pediatria, 1987, Volume: 26, Issue:2

    Topics: Adolescent; Antiemetics; Basal Ganglia Diseases; Benzamides; Child; Child, Preschool; Female; Halope

1987
[The dystonic-hyperkinetic syndrome. A case report on the knowledge of drug side-effects in children].
    Wiener medizinische Wochenschrift (1946), 1974, Apr-27, Volume: 124, Issue:17

    Topics: Adolescent; Child; Diazepam; Drug Hypersensitivity; Female; Humans; Hyperkinesis; Male; Metocloprami

1974