Page last updated: 2024-10-31

metoclopramide and Serotonin Syndrome

metoclopramide has been researched along with Serotonin Syndrome in 5 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.

Research Excerpts

ExcerptRelevanceReference
"A 40-year-old woman with bipolar disorder who was taking mirtazapine presented with mydriasis, abnormal diaphoresis, myoclonus and muscle rigidity after taking metocloplamide."7.85Metoclopramide-induced Serotonin Syndrome. ( Harada, T; Hirosawa, T; Morinaga, K; Shimizu, T, 2017)
"To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine."7.71Serotonin syndrome caused by selective serotonin reuptake-inhibitors-metoclopramide interaction. ( Davis, MW; Fisher, AA, 2002)
"The authors report the case of a patient who developed a serotonin syndrome after taking sertraline and metoclopramide."7.70[Serotonin syndrome secondary to the use of sertraline and metoclopramide]. ( Beukinga, I; Nève, P; Vandemergel, X, 2000)
"A 40-year-old woman with bipolar disorder who was taking mirtazapine presented with mydriasis, abnormal diaphoresis, myoclonus and muscle rigidity after taking metocloplamide."3.85Metoclopramide-induced Serotonin Syndrome. ( Harada, T; Hirosawa, T; Morinaga, K; Shimizu, T, 2017)
"To report 2 cases of serotonin syndrome with serious extrapyramidal movement disorders occurring when metoclopramide was coadministered with sertraline or venlafaxine."3.71Serotonin syndrome caused by selective serotonin reuptake-inhibitors-metoclopramide interaction. ( Davis, MW; Fisher, AA, 2002)
"The authors report the case of a patient who developed a serotonin syndrome after taking sertraline and metoclopramide."3.70[Serotonin syndrome secondary to the use of sertraline and metoclopramide]. ( Beukinga, I; Nève, P; Vandemergel, X, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harada, T1
Hirosawa, T1
Morinaga, K1
Shimizu, T1
Lalondriz Bueno, YM1
Monereo Muñoz, MB1
Ripper, CJ1
Santolaria, F1
Colomar Ferrá, A1
Ventayol Bosch, P1
Raurich, JM1
Vandemergel, X1
Beukinga, I1
Nève, P1
Fisher, AA1
Davis, MW1

Other Studies

5 other studies available for metoclopramide and Serotonin Syndrome

ArticleYear
Metoclopramide-induced Serotonin Syndrome.
    Internal medicine (Tokyo, Japan), 2017, Volume: 56, Issue:6

    Topics: Adult; Antiemetics; Bipolar Disorder; Drug Interactions; Female; Humans; Metoclopramide; Mianserin;

2017
[Serotoninergic syndrome due to linezolid and metoclopramide].
    Enfermedades infecciosas y microbiologia clinica, 2014, Volume: 32, Issue:10

    Topics: Aged; Anti-Bacterial Agents; Antiemetics; Female; Humans; Linezolid; Metoclopramide; Serotonin Syndr

2014
[Serotonin syndrome due to interaction between linezolid, tryptophan, and metoclopramide].
    Medicina intensiva, 2009, Volume: 33, Issue:7

    Topics: Acetamides; Drug Interactions; Female; Humans; Linezolid; Metoclopramide; Middle Aged; Oxazolidinone

2009
[Serotonin syndrome secondary to the use of sertraline and metoclopramide].
    Revue medicale de Bruxelles, 2000, Volume: 21, Issue:3

    Topics: Adult; Antiemetics; Cyproheptadine; Drug Combinations; Humans; Male; Metoclopramide; Selective Serot

2000
Serotonin syndrome caused by selective serotonin reuptake-inhibitors-metoclopramide interaction.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:1

    Topics: Accidental Falls; Adult; Aged; Basal Ganglia Diseases; Cyclohexanols; Depressive Disorder; Dopamine

2002