metoclopramide has been researched along with Scleroderma, Systemic in 9 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Scleroderma, Systemic: A chronic multi-system disorder of CONNECTIVE TISSUE. It is characterized by SCLEROSIS in the SKIN, the LUNGS, the HEART, the GASTROINTESTINAL TRACT, the KIDNEYS, and the MUSCULOSKELETAL SYSTEM. Other important features include diseased small BLOOD VESSELS and AUTOANTIBODIES. The disorder is named for its most prominent feature (hard skin), and classified into subsets by the extent of skin thickening: LIMITED SCLERODERMA and DIFFUSE SCLERODERMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We report a case of cardiac arrest after uncomplicated regional anesthesia in a patient with scleroderma who received labetalol and metoclopramide after surgery." | 1.31 | Cardiac arrest after labetalol and metoclopramide administration in a patient with scleroderma. ( Cutter, T; Sweitzer, B; Tung, A, 2002) |
| "Metoclopramide improved lower esophageal sphincter pressure and reduced the gastric emptying delay and gastroesophageal reflux in most patients but had a less consistent effect improving esophageal transit or esophageal body pressures." | 1.27 | Metoclopramide response in patients with progressive systemic sclerosis. Effect on esophageal and gastric motility abnormalities. ( Benjamin, SB; Cattau, EL; Chobanian, SJ; Curran, J; Drane, WE; Johnson, DA; Karvelis, K, 1987) |
| "Progressive systemic sclerosis alters smooth muscle function throughout the gastrointestinal tract." | 1.26 | Abnormal colonic motility in progressive systemic sclerosis. ( Battle, WM; Cohen, S; Meyers, A; Snape, WJ; Sullivan, MA; Tuthill, R; Wright, S, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tung, A | 1 |
| Sweitzer, B | 1 |
| Cutter, T | 1 |
| Wollheim, FA | 1 |
| Akesson, A | 1 |
| Rees, WD | 1 |
| Leigh, RJ | 1 |
| Christofides, ND | 1 |
| Bloom, SR | 1 |
| Turnberg, LA | 1 |
| Minami, H | 1 |
| McCallum, RW | 2 |
| Burns, TW | 1 |
| Battle, WM | 1 |
| Snape, WJ | 1 |
| Wright, S | 1 |
| Sullivan, MA | 1 |
| Cohen, S | 1 |
| Meyers, A | 1 |
| Tuthill, R | 1 |
| Sridhar, KR | 1 |
| Lange, RC | 1 |
| Magyar, L | 1 |
| Soykan, I | 1 |
| Drane, WE | 2 |
| Karvelis, K | 2 |
| Johnson, DA | 2 |
| Curran, JJ | 1 |
| Silverman, ED | 1 |
| Curran, J | 1 |
| Benjamin, SB | 1 |
| Chobanian, SJ | 1 |
| Cattau, EL | 1 |
1 review available for metoclopramide and Scleroderma, Systemic
| Article | Year |
|---|---|
The physiology and pathophysiology of gastric emptying in humans.
Topics: Achlorhydria; Anemia, Pernicious; Anorexia Nervosa; Gastric Emptying; Gastritis, Atrophic; Gastroeso | 1984 |
1 trial available for metoclopramide and Scleroderma, Systemic
| Article | Year |
|---|---|
Prevalence of impaired gastric emptying of solids in systemic sclerosis: diagnostic and therapeutic implications.
Topics: Adult; Aged; Antiemetics; Esophagus; Female; Gastric Emptying; Gastroesophageal Reflux; Humans; Inje | 1998 |
7 other studies available for metoclopramide and Scleroderma, Systemic
| Article | Year |
|---|---|
Cardiac arrest after labetalol and metoclopramide administration in a patient with scleroderma.
Topics: Adult; Antiemetics; Antihypertensive Agents; Female; Heart Arrest; Humans; Labetalol; Metoclopramide | 2002 |
Management of intestinal involvement in systemic sclerosis.
Topics: Domperidone; Dopamine Antagonists; Gastrointestinal Agents; Gastroparesis; Humans; Indoles; Metoclop | 2007 |
Interdigestive motor activity in patients with systemic sclerosis.
Topics: Adult; Bethanechol; Bethanechol Compounds; Duodenum; Fasting; Female; Gastrointestinal Motility; Hum | 1982 |
Motor disorders of the esophagus: diagnosis and treatment.
Topics: Bethanechol Compounds; Calcium Channel Blockers; Esophageal Achalasia; Esophageal Diseases; Esophagi | 1984 |
Abnormal colonic motility in progressive systemic sclerosis.
Topics: Adult; Aged; Colon; Female; Gastrointestinal Motility; Humans; Male; Metoclopramide; Middle Aged; Ne | 1981 |
Scintigraphic detection of metoclopramide esophageal stimulation in progressive systemic sclerosis.
Topics: Adult; Aged; Esophagus; Female; Humans; Male; Manometry; Metoclopramide; Middle Aged; Peristalsis; R | 1987 |
Metoclopramide response in patients with progressive systemic sclerosis. Effect on esophageal and gastric motility abnormalities.
Topics: Adult; Aged; Esophagus; Female; Gastric Emptying; Gastrointestinal Motility; Humans; Hydrogen-Ion Co | 1987 |