metoclopramide has been researched along with Pregnancy in 269 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The EMPOWER (EMesis in Pregnancy – Ondansetron With mEtoClopRamide) trial aimed to compare the clinical effectiveness and cost-effectiveness of two anti-sickness drugs [metoclopramide (metoclopramide hydrochloride, Actavis UK Ltd, Barnstable, UK; IV Ratiopharm GmbH, Ulm, Germany) and ondansetron (ondansetron hydrochloride dehydrate, Wockhardt UK Ltd, Wrexham, UK; IV Hameln Pharma plus GmbH, Hameln)] for the treatment of nausea and vomiting in pregnancy." | 9.41 | Ondansetron and metoclopramide as second-line antiemetics in women with nausea and vomiting in pregnancy: the EMPOWER pilot factorial RCT. ( Campbell, I; Fernandez-Garcia, C; Goudie, N; Graham, R; Howel, D; Lie, M; McColl, E; McParlin, C; Mossop, H; Nadeem, A; Nelson-Piercy, C; O'Hara, ME; Phillipson, J; Robson, S; Shehmar, M; Simpson, N; Steel, A; Ternent, L; Tuffnell, D; Williams, R, 2021) |
| "We investigated whether metoclopramide administered with diphenhydramine (MAD) relieves headache in pregnant women when acetaminophen alone is ineffective, using codeine for comparison." | 9.27 | Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). ( Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ, 2018) |
| "Our study proved the functionality of metoclopramide in preventing ileus." | 9.20 | Metoclopramide role in preventing ileus after cesarean, a clinical trial. ( Agah, J; Baghani, R; Rad, A; Rakhshani, MH, 2015) |
| "To compare ondansetron with metoclopramide in the treatment of hyperemesis gravidarum." | 9.19 | Ondansetron compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. ( Abas, MN; Azmi, N; Omar, SZ; Tan, PC, 2014) |
| "This study assesses the effects of ginger on nausea and vomiting caused by pregnancy and compares it with metoclopramide medicine." | 9.15 | Comparing the effects of ginger and metoclopramide on the treatment of pregnancy nausea. ( Farhadifar, F; Mohammadbeigi, R; Rezaiie, M; Shahgeibi, S; Soufizadeh, N, 2011) |
| "To evaluate oral pyridoxine in conjunction with standard therapy in women hospitalized for hyperemesis gravidarum (HG)." | 9.14 | A placebo-controlled trial of oral pyridoxine in hyperemesis gravidarum. ( Omar, SZ; Tan, PC; Yow, CM, 2009) |
| "To compare the effects of promethazine with those of metoclopramide for hyperemesis gravidarum." | 9.14 | Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. ( Khine, PP; Omar, SZ; Tan, PC; Vallikkannu, N, 2010) |
| "We previously determined that a single dose of metoclopramide could significantly reduce the patient-controlled analgesia (PCA) morphine requirements of women undergoing prostaglandin-induced termination of pregnancy." | 9.07 | Metoclopramide-enhanced analgesia for prostaglandin-induced termination of pregnancy. ( Cioffi, AM; Rosenblatt, WH; Silverman, DG; Sinatra, R, 1992) |
| "To examine the medical evidence regarding the clinical efficacy and cost-effectiveness of the application of continuous subcutaneous metoclopramide and ondansetron to treat nausea and vomiting during pregnancy." | 8.88 | Reviewing the evidence for using continuous subcutaneous metoclopramide and ondansetron to treat nausea & vomiting during pregnancy. ( Kirkbride, MS; Reichmann, JP, 2012) |
| " The EMA-warning on metoclopramide in 2013 temporarily limited pre-hospital antiemetic provision associated with hospitalization at lower gestational length and indication of an increase in termination of pregnancy." | 8.12 | Antiemetic treatment of hyperemesis gravidarum in 1,064 Norwegian women and the impact of European warning on metoclopramide: a retrospective cohort study 2002-2019. ( Erdal, H; Heitmann, K; Holst, L; Trovik, J, 2022) |
| "Ondansetron is commonly used to treat nausea and vomiting in pregnancy despite inconclusive evidence of its safety." | 8.02 | Ondansetron use in early pregnancy and the risk of miscarriage. ( Boggess, K; Engel, SM; Jonsson Funk, M; Lund, JL; Stürmer, T; Suarez, EA, 2021) |
| "The objective of the study was to evaluate the rate of major congenital anomalies after first trimester exposure to ondansetron for nausea and vomiting of pregnancy (NVP)." | 8.02 | Pregnancy outcome following in-utero exposure to ondansetron: A prospective comparative observational study. ( Arnon, J; Diav-Citrin, O; Sakran, R; Shechtman, S, 2021) |
| "We report a 33-year-old woman, gravida 2 para 1, with previous mild hypertension, was admitted to the emergency room, at 28 2/7 weeks of gestation due to headache, tachycardia and severe arterial hypertension (220/120 mm Hg) triggered by the antiemetic metoclopramide used for a week because of nausea." | 8.02 | Unrecognised pheochromocytoma in pregnancy discovered through metoclopramide-triggered hypertensive emergency. ( Cabassi, A; Calvi, A; Coghi, P; Cunzi, D; Giunta, A; Negro, A; Palladini, B; Santi, R; Tedeschi, S; Verzicco, I; Volpi, R, 2021) |
| "OBJECTIVE To investigate effects of metoclopramide orally administered to healthy bitches on serum prolactin and milk lactose concentrations, gross energy, and dry matter content and on puppy weight gain during early lactation." | 7.88 | Effect of metoclopramide treatment of bitches during the first week of lactation on serum prolactin concentration, milk composition, and milk yield and on weight gain of their puppies. ( Abonyi-Tóth, Z; Austin, SC; Balogh, O; Keller, SR; Liesegang, A; Oei, CHY; Reichler, IM; Sprenger, N; Wichert, BAC, 2018) |
| "Metoclopramide exposure, especially in high doses may alter endometrial receptivity by effecting integrin expression on decidual tissue which can decrease pregnancy rates." | 7.83 | Does metoclopramide exposure alter endometrial receptivity and decrease pregnancy rates? ( Akpak, YK; Çakır, A; Çekmez, Y; Ergün, Y; Göçmen, A; Gülşen, S; Korkmaz, V, 2016) |
| "Metoclopramide use in pregnancy was not associated with increased risk of major congenital malformations overall, any of the 20 individual malformation categories assessed, spontaneous abortion, or stillbirth." | 7.79 | Metoclopramide in pregnancy and risk of major congenital malformations and fetal death. ( Hviid, A; Melbye, M; Mølgaard-Nielsen, D; Pasternak, B; Svanström, H, 2013) |
| "The new protocol consisting of the combination of metoclopramide and diphenhydramine appears to be a good option in the management of hyperemesis gravidarum." | 7.75 | Metoclopramide and diphenhydramine in the treatment of hyperemesis gravidarum: effectiveness and predictors of rehospitalisation. ( Bérard, A; Ferreira, E; Lacasse, A; Lagoutte, A, 2009) |
| "In various countries, metoclopramide is the antiemetic drug of choice in pregnant women, but insufficient information exists regarding its safety in pregnancy." | 7.75 | The safety of metoclopramide use in the first trimester of pregnancy. ( Gorodischer, R; Koren, G; Levy, A; Matok, I; Sheiner, E; Wiznitzer, A, 2009) |
| ") metoclopramide in the outpatient treatment of hyperemesis gravidarum." | 7.70 | Home subcutaneous metoclopramide therapy for hyperemesis gravidarum. ( Bergauer, NK; Buttino, L; Coleman, SK; Gambon, C; Stanziano, GJ, 2000) |
| "To investigate if an association exists in parous women between metoclopramide-induced prolactin (PRL) release and chronological age at first full-term pregnancy and to compare their response to a group of non-parous women, we studied 139 healthy, non-lactating women, aged 15." | 7.69 | Differences in the metoclopramide-induced prolactin release related to age at first full-term pregnancy or nulliparity. ( Barrón, J; Coria, I; Espinosa de los Monteros, A; Parra, A; Sinibaldi, J, 1997) |
| "Prolactin (PRL) response to an intravenous administration of metoclopramide (10 mg) was examined during normal pregnancy and puerperium." | 7.67 | Prolactin secretion during pregnancy and puerperium: response to metoclopramide and interactions with placental hormones. ( Bohnet, HG; Kato, K, 1985) |
| " We have compared the TSH and PRL responses to metoclopramide (MCP) in normal and postpartum lactating women with those in 28 patients with hyperprolactinemia of different origin." | 7.67 | Evaluation of dopaminergic tone in hyperprolactinemia. III. Thyroid-stimulating hormone response to metoclopramide in differential diagnosis and postoperative follow-up of prolactinoma patients. ( Anile, C; Barbarino, A; De Marinis, L; Maira, G; Mancini, A; Masala, R; Minnielli, S, 1985) |
| "This study was designed to ascertain whether gastric volume in early pregnancy is unduly large, and to determine whether preanesthetic administration of metoclopramide decreases this volume." | 7.66 | Gastric volume in early pregnancy: effect of metoclopramide. ( Cohen, SE; Wyner, J, 1982) |
| "The effect of metoclopramide on plasma prolactin levels was studied in 10 women in the second half of pregnancy." | 7.66 | The acute effect of metoclopramide on plasma prolactin during pregnancy. ( Barzilai, D; Brandes, JM; Fisher, M; Itskovitz, J; Shen-Orr, Z, 1981) |
| "The degree of autonomy in prolactin secreting pituitary adenomas and also prolactin secretory reserve in cases with suspected functional galactorrhea syndrome was evaluated with the use of metoclopramide, TRH and L-DOPA." | 7.66 | The effect of metoclopramide, TRH and L-dopa on prolactin secretion in pituitary adenoma and in "functional" galactorrhoea syndrome. ( Jeske, W, 1979) |
| "The clinical courses of galactorrhea and menstrual disorders were studied in 18 women with galactorrhea induced by sulpiride (SLP) or metoclopramide (MCP) given for the treatment of gastrointestinal diseases." | 7.66 | Clinical and endocrinological analyses of patients with galactorrhea and menstrual disorders due to sulpiride or metoclopramide. ( Aono, T; Kinugasa, T; Kurachi, K; Onishi, T; Shioji, T, 1978) |
| "The effects of intravenous metoclopramide (Maxolon) on the lower oesophageal sphincter (LOS) were studied in three groups of patients, one group being normal control and the other two being pregnant females, one without heartburn and the other with." | 7.66 | The effect of metoclopramide on the lower oesophageal sphincter in late pregnancy. ( Brock-Utne, JG; Dimopoulos, GE; Dow, TG; Moshal, MG; Welman, S, 1978) |
| "Pain is often cited as one of the worst features of medical abortion." | 6.82 | Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days' gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial. ( Dragoman, MV; Dung, DL; Grossman, D; Habib, N; Huong, NM; Kapp, N; Tamang, A, 2016) |
| "Metoclopramide is a prokinetic agent reported to be safe in parturients." | 6.48 | Metoclopramide for nausea and vomiting prophylaxis during and after Caesarean delivery: a systematic review and meta-analysis. ( Habib, AS; Mishriky, BM, 2012) |
| "Metoclopramide, 4-amino-5-chloro-2-methoxy-N-(2-diethyl-aminoethyl) benzamide, is advocated for use in gastro-intestinal diagnostics, and in treating various types of vomiting and a variety of functional and organic gastro-intestinal disorders." | 6.14 | Metoclopramide: a review of its pharmacological properties and clinical use. ( Avery, GS; Brogden, RN; Pinder, RM; Sawyer, PR; Speight, TM, 1976) |
| "Metoclopramide decreases gastric volume, reduces postoperative nausea and vomiting, and may lower the risk of aspiration when used as premedication before obstetric surgery." | 5.69 | Ultrasonographic assessment of metoclopramide effect on gastric volume in parturients females undergoing Caesarean section: a randomized double blind study. ( Farghaly, TA; Hamed, E; Hamed, R; Hamza, WS, 2023) |
| " The EMPOWER (EMesis in Pregnancy – Ondansetron With mEtoClopRamide) trial aimed to compare the clinical effectiveness and cost-effectiveness of two anti-sickness drugs [metoclopramide (metoclopramide hydrochloride, Actavis UK Ltd, Barnstable, UK; IV Ratiopharm GmbH, Ulm, Germany) and ondansetron (ondansetron hydrochloride dehydrate, Wockhardt UK Ltd, Wrexham, UK; IV Hameln Pharma plus GmbH, Hameln)] for the treatment of nausea and vomiting in pregnancy." | 5.41 | Ondansetron and metoclopramide as second-line antiemetics in women with nausea and vomiting in pregnancy: the EMPOWER pilot factorial RCT. ( Campbell, I; Fernandez-Garcia, C; Goudie, N; Graham, R; Howel, D; Lie, M; McColl, E; McParlin, C; Mossop, H; Nadeem, A; Nelson-Piercy, C; O'Hara, ME; Phillipson, J; Robson, S; Shehmar, M; Simpson, N; Steel, A; Ternent, L; Tuffnell, D; Williams, R, 2021) |
| "The impact of hyperprolactinaemia on endometrial function, along with embryo implantation, has been the subject of discussion." | 5.33 | Metoclopramide-induced hyperprolactinaemia caused marked decline in pinopodes and pregnancy rates in mice. ( Baptista, HA; Baracat, EC; da Motta, EL; de Jesus Simões, M; Haapalainen, EF; Haidar, MA; Júnior, JM; Panzan, MQ, 2006) |
| "Metoclopramide is a dopamine receptor blocking drug that is commonly used to treat nausea and vomiting." | 5.31 | Metoclopramide for nausea and vomiting of pregnancy: a prospective multicenter international study. ( Addis, A; Arnon, J; Berkovitch, M; Elbirt, D; Greenberg, R; Magee, L; Mazzota, P; Merlob, P; Moretti, M; Ornoy, A; Schuler-Faccini, L; Stahl, B, 2002) |
| "Pheochromocytoma is a rare disease that may occur during pregnancy." | 5.30 | Pheochromocytoma in pregnancy manifesting hypertensive crisis induced by metoclopramide. ( Kinoshita, K; Seki, H; Takai, Y, 1997) |
| "The aldosterone levels were significantly greater in umbilical veins and artery than in maternal peripheral veins." | 5.28 | [Dopaminergic control of aldosterone and prolactin secretion during normal pregnancy and toxemia of pregnancy]. ( Niibe, T, 1989) |
| "We investigated whether metoclopramide administered with diphenhydramine (MAD) relieves headache in pregnant women when acetaminophen alone is ineffective, using codeine for comparison." | 5.27 | Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). ( Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ, 2018) |
| "Our study proved the functionality of metoclopramide in preventing ileus." | 5.20 | Metoclopramide role in preventing ileus after cesarean, a clinical trial. ( Agah, J; Baghani, R; Rad, A; Rakhshani, MH, 2015) |
| "To compare ondansetron with metoclopramide in the treatment of hyperemesis gravidarum." | 5.19 | Ondansetron compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. ( Abas, MN; Azmi, N; Omar, SZ; Tan, PC, 2014) |
| "To estimate whether the addition of metoclopramide or its combination with ondansetron to a prophylactic phenylephrine infusion provides improved intraoperative nausea and vomiting prophylaxis compared with phenylephrine infusion alone." | 5.17 | Antiemetics added to phenylephrine infusion during cesarean delivery: a randomized controlled trial. ( Allen, TK; George, RB; Habib, AS; Ituk, US; McKeen, DM; Megalla, SA; White, WD, 2013) |
| "Analysis by time yielded no statistically significant difference in VAS scores between the groups at any point except 16-20 hours after induction of labor, when pain was lower in the tramadol group (11." | 5.16 | Tramadol-metoclopramide or remifentanil for patient-controlled analgesia during second trimester abortion: a double-blinded, randomized controlled trial. ( Chinchuck, A; Eidelman, LA; Nichinson, E; Nitke, S; Orbach-Zinger, S; Paul-Keslin, L, 2012) |
| " Women who delivered at ≤34 weeks of gestation, with no prior breastfeeding experience, singleton pregnancy, and no contraindications to using metoclopramide were eligible for entry." | 5.15 | Metoclopramide to augment lactation, does it work? A randomized trial. ( Angello, C; Boswell, S; Fife, S; Gill, P; Hopkins, M; Nelson, KM, 2011) |
| "This study assesses the effects of ginger on nausea and vomiting caused by pregnancy and compares it with metoclopramide medicine." | 5.15 | Comparing the effects of ginger and metoclopramide on the treatment of pregnancy nausea. ( Farhadifar, F; Mohammadbeigi, R; Rezaiie, M; Shahgeibi, S; Soufizadeh, N, 2011) |
| "To evaluate oral pyridoxine in conjunction with standard therapy in women hospitalized for hyperemesis gravidarum (HG)." | 5.14 | A placebo-controlled trial of oral pyridoxine in hyperemesis gravidarum. ( Omar, SZ; Tan, PC; Yow, CM, 2009) |
| "Phenylephrine 100 mug and ephedrine 6 mg had similar efficacy in the treatment of maternal hypotension during spinal anaesthesia for elective caesarean delivery." | 5.14 | Maternal and neonatal effects of bolus administration of ephedrine and phenylephrine during spinal anaesthesia for caesarean delivery: a randomised study. ( Chellani, H; Gogia, AR; Prakash, S; Pramanik, V; Salhan, S, 2010) |
| "To compare the effects of promethazine with those of metoclopramide for hyperemesis gravidarum." | 5.14 | Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial. ( Khine, PP; Omar, SZ; Tan, PC; Vallikkannu, N, 2010) |
| "Metoclopramide use during first trimester of pregnancy was not associated with the risk of major congenital malformations." | 5.12 | Use of metoclopramide in the first trimester and risk of major congenital malformations: A systematic review and meta-analysis. ( Sun, L; Wen, X; Xi, Y; Zou, W, 2021) |
| " In addition postoperative morphine requirement, anxiety, and vomiting were not affected by the music during general anesthesia." | 5.12 | The impact of music on postoperative pain and anxiety following cesarean section. ( Abul-Qasim, A; Ali, SM; Reza, N; Reza, TH; Saeed, K, 2007) |
| "This study compares pyridoxine-metoclopramide combination therapy to prochlorperazine and promethazine monotherapies in the outpatient treatment of nausea and vomiting in pregnancy." | 5.10 | Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy. ( Bsat, FA; Hoffman, DE; Seubert, DE, 2003) |
| "We have studied the antiemetic efficacy of droperidol alone, and in combination with metoclopramide in first trimester termination of pregnancy in day surgery." | 5.08 | A comparison of antiemetic efficacy of droperidol alone and in combination with metoclopramide in day surgery anaesthesia. ( Loo, CC; Sia, TH; Tan, HM; Thomas, E, 1997) |
| "Tiapride (Tiapridal, Delagrange), a dopaminergic D2 receptor blocking agent having anxiolytic, sedative, antiemetic and analgesic properties was compared with metoclopramide and placebo in a randomized double-blind trial to determine its effects on post-operative nausea, vomiting, and sedation." | 5.07 | Tiapride versus metoclopramide: comparison after minor gynaecological surgery. ( Joshi, R; Sivaganesanathan, A, 1993) |
| "We previously determined that a single dose of metoclopramide could significantly reduce the patient-controlled analgesia (PCA) morphine requirements of women undergoing prostaglandin-induced termination of pregnancy." | 5.07 | Metoclopramide-enhanced analgesia for prostaglandin-induced termination of pregnancy. ( Cioffi, AM; Rosenblatt, WH; Silverman, DG; Sinatra, R, 1992) |
| " Women in the bromocriptine group (except manifestly hyperprolactinaemic patients) had significantly higher pregnancy rates than those not treated with bromocriptine." | 5.07 | [Value of the metoclopramide test in diagnosis of hormonal causes of female sterility]. ( Gerhard, I; Matt, O; Runnebaum, B, 1992) |
| "This randomized, double-blind trial evaluated the effect of metoclopramide on the pain and analgesic requirements associated with prostaglandin-induced labor for second-trimester termination of pregnancy." | 5.07 | Metoclopramide: an analgesic adjunct to patient-controlled analgesia. ( Cioffi, AM; Rosenblatt, WH; Saberski, LR; Silverman, DG; Sinatra, R, 1991) |
| "Twenty-seven healthy females referred for legal abortion between the sixth and ninth week of pregnancy were treated for 1 week with either bromocriptine, metoclopramide or placebo." | 5.05 | Ovarian and placental hormones during prolactin suppression and stimulation in early human pregnancy. ( Andersen, AN; Arends, J; Eskildsen, PC; Hertz, J; Kjer, JJ; Larsen, PS; Nielsen, J; Svenstrup, B, 1980) |
| "To examine the medical evidence regarding the clinical efficacy and cost-effectiveness of the application of continuous subcutaneous metoclopramide and ondansetron to treat nausea and vomiting during pregnancy." | 4.88 | Reviewing the evidence for using continuous subcutaneous metoclopramide and ondansetron to treat nausea & vomiting during pregnancy. ( Kirkbride, MS; Reichmann, JP, 2012) |
| " The EMA-warning on metoclopramide in 2013 temporarily limited pre-hospital antiemetic provision associated with hospitalization at lower gestational length and indication of an increase in termination of pregnancy." | 4.12 | Antiemetic treatment of hyperemesis gravidarum in 1,064 Norwegian women and the impact of European warning on metoclopramide: a retrospective cohort study 2002-2019. ( Erdal, H; Heitmann, K; Holst, L; Trovik, J, 2022) |
| "Ondansetron is commonly used to treat nausea and vomiting in pregnancy despite inconclusive evidence of its safety." | 4.02 | Ondansetron use in early pregnancy and the risk of miscarriage. ( Boggess, K; Engel, SM; Jonsson Funk, M; Lund, JL; Stürmer, T; Suarez, EA, 2021) |
| "The objective of the study was to evaluate the rate of major congenital anomalies after first trimester exposure to ondansetron for nausea and vomiting of pregnancy (NVP)." | 4.02 | Pregnancy outcome following in-utero exposure to ondansetron: A prospective comparative observational study. ( Arnon, J; Diav-Citrin, O; Sakran, R; Shechtman, S, 2021) |
| "We report a 33-year-old woman, gravida 2 para 1, with previous mild hypertension, was admitted to the emergency room, at 28 2/7 weeks of gestation due to headache, tachycardia and severe arterial hypertension (220/120 mm Hg) triggered by the antiemetic metoclopramide used for a week because of nausea." | 4.02 | Unrecognised pheochromocytoma in pregnancy discovered through metoclopramide-triggered hypertensive emergency. ( Cabassi, A; Calvi, A; Coghi, P; Cunzi, D; Giunta, A; Negro, A; Palladini, B; Santi, R; Tedeschi, S; Verzicco, I; Volpi, R, 2021) |
| "Using the Quebec Pregnancy Cohort (1998-2015), first-trimester doxylamine-pyridoxine, metoclopramide, and ondansetron exposures were assessed for their association with MCM." | 3.91 | New evidence for concern over the risk of birth defects from medications for nausea and vomitting of pregnancy. ( Bérard, A; Bernatsky, S; Gorgui, J; Sheehy, O; Soares de Moura, C; Zhao, JP, 2019) |
| "OBJECTIVE To investigate effects of metoclopramide orally administered to healthy bitches on serum prolactin and milk lactose concentrations, gross energy, and dry matter content and on puppy weight gain during early lactation." | 3.88 | Effect of metoclopramide treatment of bitches during the first week of lactation on serum prolactin concentration, milk composition, and milk yield and on weight gain of their puppies. ( Abonyi-Tóth, Z; Austin, SC; Balogh, O; Keller, SR; Liesegang, A; Oei, CHY; Reichler, IM; Sprenger, N; Wichert, BAC, 2018) |
| "The use of ondansetron in the ED for nausea and vomiting of pregnancy was associated with similar mean time from administration to disposition as other antiemetics." | 3.81 | Comparison of antiemetics for nausea and vomiting of pregnancy in an emergency department setting. ( Gray, R; Lopes, V; Matteson, KA; Mayhall, EA, 2015) |
| "Metoclopramide use in pregnancy was not associated with increased risk of major congenital malformations overall, any of the 20 individual malformation categories assessed, spontaneous abortion, or stillbirth." | 3.79 | Metoclopramide in pregnancy and risk of major congenital malformations and fetal death. ( Hviid, A; Melbye, M; Mølgaard-Nielsen, D; Pasternak, B; Svanström, H, 2013) |
| " For morning sickness, 89% of those replying give dietary advice frequently or always, and 70% prescribe metoclopramide frequently or always, whereas 59% advise pyridoxine and 10% prescribe doxylamine." | 3.79 | A survey of prescribing for the management of nausea and vomiting in pregnancy in Australasia. ( Raymond, SH, 2013) |
| "We examined treatment outcomes in women with severe nausea and vomiting of pregnancy (NVP) receiving outpatient nursing support and either subcutaneous metoclopramide or subcutaneous ondansetron via a microinfusion pump." | 3.77 | Treatment of severe nausea and vomiting of pregnancy with subcutaneous medications. ( Desch, C; Fox, NS; Istwan, N; Klauser, CK; Palmer, B; Rebarber, A; Rhea, D; Saltzman, D, 2011) |
| "The new protocol consisting of the combination of metoclopramide and diphenhydramine appears to be a good option in the management of hyperemesis gravidarum." | 3.75 | Metoclopramide and diphenhydramine in the treatment of hyperemesis gravidarum: effectiveness and predictors of rehospitalisation. ( Bérard, A; Ferreira, E; Lacasse, A; Lagoutte, A, 2009) |
| "In various countries, metoclopramide is the antiemetic drug of choice in pregnant women, but insufficient information exists regarding its safety in pregnancy." | 3.75 | The safety of metoclopramide use in the first trimester of pregnancy. ( Gorodischer, R; Koren, G; Levy, A; Matok, I; Sheiner, E; Wiznitzer, A, 2009) |
| "Metoclopramide is an antiemetic drug used widely during pregnancy for nausea and vomiting." | 3.70 | Birth outcome following maternal use of metoclopramide. The Euromap study group. ( Baron, J; Christensen, K; Ekbom, A; Nielsen, GL; Sørensen, HT; Tage-Jensen, U, 2000) |
| ") metoclopramide in the outpatient treatment of hyperemesis gravidarum." | 3.70 | Home subcutaneous metoclopramide therapy for hyperemesis gravidarum. ( Bergauer, NK; Buttino, L; Coleman, SK; Gambon, C; Stanziano, GJ, 2000) |
| "The purpose of this study was to investigate hypothalamic dopaminergic activity in pregnant women after the administration of metoclopramide (MCP), a dopamine receptor blocker, and to investigate the effects of MCP on the placental steroid and peptide hormones, and to clarify the prolactin (PRL) releasing mechanism in the hypothalamo-pituitary axis during pregnancy using dopaminergic agents and TRH." | 3.67 | [Study on the hypothalamic dopaminergic activity in different stages of pregnancy and non-pregnancy]. ( Kubota, T, 1984) |
| "A 27-year-old, previously healthy normotensive woman was admitted for hyperemesis gravidarum and treated with intravenous fluids and metoclopramide." | 3.67 | Acute intermittent porphyria in pregnancy. ( Arlazoroff, A; Caspi, E; Klein, C; Milo, R; Neuman, M, 1989) |
| "The effect of metoclopramide premedication on the incidence of gastric regurgitation and postoperative nausea and vomiting was studied in 101 women during gynaecological procedures performed under mask anaesthesia." | 3.67 | Silent regurgitation in day case gynaecological patients. ( Anderson, WG; Miller, CD, 1988) |
| " Vomiting was a frequent side effect (about 20 per cent of cases) and was treated successfully with metoclopramide at a dosage of 0." | 3.67 | Treatment of pseudopregnancy with bromocriptin, an ergot alkaloid. ( Janssens, LA, 1986) |
| "Metoclopramide treatment has been shown to augment milk production by stimulating prolactin secretion in women in whom lactational insufficiency develops after a full-term pregnancy." | 3.67 | Metoclopramide effect on faltering milk production by mothers of premature infants. ( Ackerman, BA; Ehrenkranz, RA, 1986) |
| " week of pregnancy the serum prolactin concentration excessively increased by bolus injection of 10 mg metoclopramide." | 3.67 | [Relation between corpus luteum function and serum prolactin concentration early in pregnancy]. ( Hälbig, R; Stubert, B; Zimmermann, G, 1986) |
| "Prolactin (PRL) response to an intravenous administration of metoclopramide (10 mg) was examined during normal pregnancy and puerperium." | 3.67 | Prolactin secretion during pregnancy and puerperium: response to metoclopramide and interactions with placental hormones. ( Bohnet, HG; Kato, K, 1985) |
| " We have compared the TSH and PRL responses to metoclopramide (MCP) in normal and postpartum lactating women with those in 28 patients with hyperprolactinemia of different origin." | 3.67 | Evaluation of dopaminergic tone in hyperprolactinemia. III. Thyroid-stimulating hormone response to metoclopramide in differential diagnosis and postoperative follow-up of prolactinoma patients. ( Anile, C; Barbarino, A; De Marinis, L; Maira, G; Mancini, A; Masala, R; Minnielli, S, 1985) |
| "TRH, metoclopramide (MCP), chlorpromazine (CPZ), and insulin (ITT) stimulation tests of PRL secretion were carried out in age-matched controls and before and after successful removal of pituitary prolactinomas in women with the galactorrhea-amenorrhea syndrome." | 3.66 | Persistent defect in regulation of prolactin secretion after successful pituitary tumor removal in women with the galactorrhea-amenorrhea syndrome. ( Blackard, WG; Gardner, DF; Lankford, HV; Tucker, HS, 1980) |
| " Her pregnancy was induced by pituitary gonadotrophins and the deficient prolactin pituitary reserve was shown by means of pituitary stimulation test with metoclopramide of pituitary stimulation test with metoclopramide and TRH." | 3.66 | Serum prolactin during pregnancy induced by pituitary gonadotrophins in a patient with post partum hypopituitarism (Sheehan syndrome). ( Lee, D; León, C; Milanés, BA, 1981) |
| "Metoclopramide and bromocriptine, drugs which are respectively antagonistic and agonistic to dopamine receptor activity, were used to investigate the control of prolactin secretion in the ewe during pregnancy." | 3.66 | Effects of metoclopramide and bromocriptine on prolactin secretion in the pregnant ewe. ( Cunningham, FJ; Fitzgerald, BP, 1982) |
| "The effect of acute and chronic maternal administration of metoclopramide on prolactin levels in serum of umbilical vein and artery was investigated in 30 women with normal term pregnancy during labor." | 3.66 | Effect of metoclopramide on maternal and fetal prolactin secretion during labor. ( Dalkalitsis, N; Kanaris, C; Lolis, DE; Messinis, IE; Souvatzoglou, A, 1982) |
| "The degree of autonomy in prolactin secreting pituitary adenomas and also prolactin secretory reserve in cases with suspected functional galactorrhea syndrome was evaluated with the use of metoclopramide, TRH and L-DOPA." | 3.66 | The effect of metoclopramide, TRH and L-dopa on prolactin secretion in pituitary adenoma and in "functional" galactorrhoea syndrome. ( Jeske, W, 1979) |
| "The clinical courses of galactorrhea and menstrual disorders were studied in 18 women with galactorrhea induced by sulpiride (SLP) or metoclopramide (MCP) given for the treatment of gastrointestinal diseases." | 3.66 | Clinical and endocrinological analyses of patients with galactorrhea and menstrual disorders due to sulpiride or metoclopramide. ( Aono, T; Kinugasa, T; Kurachi, K; Onishi, T; Shioji, T, 1978) |
| "The effects of intravenous metoclopramide (Maxolon) on the lower oesophageal sphincter (LOS) were studied in three groups of patients, one group being normal control and the other two being pregnant females, one without heartburn and the other with." | 3.66 | The effect of metoclopramide on the lower oesophageal sphincter in late pregnancy. ( Brock-Utne, JG; Dimopoulos, GE; Dow, TG; Moshal, MG; Welman, S, 1978) |
| " Should a parenteral form of amoxycillin become available, a similar study of blood and liquor levels may indicate that, like ampicillin, intramuscular administration is required for adequate therapeutic use at this stage of pregnancy." | 3.65 | Gastro-intestinal absorption and transplacental transfer of amoxycillin during labour and the influence of metoclopramide. ( Buckingham, M; Elstein, M; Miller, JF; Welply, G, 1975) |
| "Gastroparesis is a functional gastrointestinal disorder that more commonly affects women, with most cases being diagnosed during childbearing age." | 3.01 | Gastroparesis in pregnancy. ( Min, YW; Moosavi, S; Rezaie, A; Wong, M, 2023) |
| "Pain is often cited as one of the worst features of medical abortion." | 2.82 | Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days' gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial. ( Dragoman, MV; Dung, DL; Grossman, D; Habib, N; Huong, NM; Kapp, N; Tamang, A, 2016) |
| "Yet data are limited addressing treatment of headache in pregnancy." | 2.72 | Randomized Controlled Trials of Headache Treatments in Pregnancy: A Systematic Review. ( Bushman, ET; Cozzi, G; Digre, K; Sinkey, RG; Smith, CH; Varner, MW, 2021) |
| "The frequency of intraoperative and postoperative vomiting were similar between Group O and Group M, but significantly higher in Group P (p < 0." | 2.70 | Comparing the efficacy of prophylactic metoclopramide, ondansetron, and placebo in cesarean section patients given epidural anesthesia. ( Moore, CH; Pan, PH, 2001) |
| "As metoclopramide is a potent inhibitor of PCHE, interactions might be expected to occur between metoclopramide and drugs that require PCHE for biotransformation, such as suxamethonium and ester local anaesthetics." | 2.67 | Dose-dependent effect of metoclopramide on cholinesterases and suxamethonium metabolism. ( Kao, YJ; Tellez, J; Turner, DR, 1990) |
| "Hyperemesis gravidarum is a severe form of nausea and vomiting in pregnancy affecting 0." | 2.53 | Interventions for treating hyperemesis gravidarum. ( Barton, SJ; Berghella, V; Boelig, RC; Edwards, SJ; Kelly, AJ; Saccone, G, 2016) |
| "Of note, co-existing gastroesophageal reflux disease (GERD), Helicobacter pylori infection, and psychosocial factors may have a negative impact on the management of NVP." | 2.50 | The outpatient management and special considerations of nausea and vomiting in pregnancy. ( Clark, SM; Dutta, E; Hankins, GD, 2014) |
| "Metoclopramide is a prokinetic agent reported to be safe in parturients." | 2.48 | Metoclopramide for nausea and vomiting prophylaxis during and after Caesarean delivery: a systematic review and meta-analysis. ( Habib, AS; Mishriky, BM, 2012) |
| "Heartburn is a normal consequence of pregnancy." | 2.43 | Review article: the management of heartburn in pregnancy. ( Richter, JE, 2005) |
| "Early pregnancy is characterized by nausea and vomiting which are the most frequent symptoms and the main reason for consulting the physician." | 2.41 | [Evaluation and treatment of hyperemesis gravidarum]. ( Accorsi, P; Aguzzoli, L; Carossino, E; Crotti, M; Gargano, G; Masellis, G, 2001) |
| " Pyridoxine is considered safe for use during pregnancy, but its efficacy in treating nausea and vomiting has not been determined." | 2.37 | Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy. ( Leathem, AM, 1986) |
| "Metoclopramide also has an important place in the investigation of the role of dopamine in physiological and pathological processes." | 2.37 | Metoclopramide--a review. ( Desmond, PV; Watson, KJ, 1986) |
| "Metoclopramide was the most frequently given as a prophylaxis for pulmonary aspiration." | 1.62 | The current practice of aspiration prophylaxis in obstetric anesthesia: a survey among non-physician anesthetic providers working in hospitals in Ethiopia. ( Fenta, E; Hunie, M; Kibret, S; Teshome, D, 2021) |
| "Acetaminophen was the most frequent medicine administered first (53%, 38/72)." | 1.51 | Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study. ( Hamilton, KT; Robbins, MS, 2019) |
| "Selfheal extract treated hyperprolactinemia through dopamine D2 receptor with significant effect." | 1.46 | The mechanism of selfheal extract in treating hyperprolactinemia. ( Luan, S; Mu, M; Sun, L, 2017) |
| "The majority reported use of antimigraine medications during pregnancy (73." | 1.43 | Use of antimigraine medications and information needs during pregnancy and breastfeeding: a cross-sectional study among 401 Norwegian women. ( Amble, NM; Amundsen, S; Nordeng, H; Poole, AC; Øvrebø, TG, 2016) |
| "Magnesium sulfate was more potent for prolonging myometrial contractile interval than reducing contractile force." | 1.40 | Relaxant effects of metoclopramide and magnesium sulfate on isolated pregnant myometrium: an in vitro study. ( Du, Y; Lin, XM; Ma, YS; Ni, J; Tang, YY; Zhou, J, 2014) |
| "Metoclopramide was associated with impaired taste and smell and hot flushes." | 1.38 | Combined use of metoclopramide and dexamethasone as a prophylactic antiemetic in elective cesarean section under spinal anesthesia. ( Abdelhamid, K; Firas, D; Lasaad, S; Mohamed, F; Riadh, B; Walid, D, 2012) |
| "The impact of hyperprolactinaemia on endometrial function, along with embryo implantation, has been the subject of discussion." | 1.33 | Metoclopramide-induced hyperprolactinaemia caused marked decline in pinopodes and pregnancy rates in mice. ( Baptista, HA; Baracat, EC; da Motta, EL; de Jesus Simões, M; Haapalainen, EF; Haidar, MA; Júnior, JM; Panzan, MQ, 2006) |
| "Drug-induced dystonia may occur within minutes or hours of exposure to an inciting drug; it is seen with familial pattern and cannot be correlated with blood level of the drug." | 1.32 | Maternal medication causing drug dystonia in a newborn: placental transfer of drugs. ( Gokhale, SG; Panchakshari, MB, 2004) |
| "Metoclopramide is a dopamine receptor blocking drug that is commonly used to treat nausea and vomiting." | 1.31 | Metoclopramide for nausea and vomiting of pregnancy: a prospective multicenter international study. ( Addis, A; Arnon, J; Berkovitch, M; Elbirt, D; Greenberg, R; Magee, L; Mazzota, P; Merlob, P; Moretti, M; Ornoy, A; Schuler-Faccini, L; Stahl, B, 2002) |
| "Metoclopramide is an antiemetic drug used frequently both in general practice and hospitals." | 1.31 | [Acute dystonia caused by metoclopramide (Afipran) therapy]. ( Bindoff, L; Farbu, E; Hagen, EM, 2001) |
| "Pheochromocytoma is a rare disease that may occur during pregnancy." | 1.30 | Pheochromocytoma in pregnancy manifesting hypertensive crisis induced by metoclopramide. ( Kinoshita, K; Seki, H; Takai, Y, 1997) |
| "Metoclopramide was administered to the ewe and fetus on separate occasions as an initial iv bolus loading dose followed by a constant-rate infusion, with steady-state maternal and fetal plasma concentrations being obtained by 45 min." | 1.28 | Fetal and maternal placental and nonplacental clearances of metoclopramide in chronically instrumented pregnant sheep. ( Axelson, JE; McErlane, BA; McMorland, GH; Riggs, KW; Rurak, DW; Taylor, SM, 1990) |
| "The aldosterone levels were significantly greater in umbilical veins and artery than in maternal peripheral veins." | 1.28 | [Dopaminergic control of aldosterone and prolactin secretion during normal pregnancy and toxemia of pregnancy]. ( Niibe, T, 1989) |
| "Metoclopramide was detectable in all the umbilical arterial and venous and amniotic fluid samples, in mean concentrations of 50, 63 and 75 ng/ml, respectively." | 1.27 | Placental transfer and hormonal effects of metoclopramide. ( Arvela, P; Jouppila, R; Kauppila, A; Pakarinen, A; Pelkonen, O; Tuimala, R, 1983) |
| "Metoclopramide was detected in all the milk samples studied, generally at a higher concentration than in maternal plasma." | 1.27 | Metoclopramide and breast feeding: transfer into milk and the newborn. ( Arvela, P; Kauppila, A; Kivinen, S; Koivisto, M; Pelkonen, O; Ylikorkala, O, 1983) |
| "Metoclopramide, 10 mg, was administered intravenously to facilitate gastric emptying and as an anti-emetic." | 1.27 | Supraventricular tachycardia associated with postpartum metoclopramide administration. ( Bevacqua, BK, 1988) |
| "Metoclopramide was administered to the ewe by intravenous bolus injections (on a crossover basis) of 10, 20, and 40 mg, with an additional 80-mg dose to the nonpregnant animals." | 1.27 | Metoclopramide pharmacokinetics in pregnant and nonpregnant sheep. ( Axelson, JE; Gruber, NC; McErlane, BA; McMorland, GH; Riggs, KW; Rurak, DW, 1988) |
| "Women with spontaneous primary hypothyroidism had a longer duration of illness (72 +/- 12 vs." | 1.26 | Hyperprolactinemia and galactorrhea: spontaneous versus iatrogenic hypothyroidism. ( Campino, C; Contreras, P; Generini, G; Michelsen, H; Pumarino, H, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 138 (51.30) | 18.7374 |
| 1990's | 38 (14.13) | 18.2507 |
| 2000's | 28 (10.41) | 29.6817 |
| 2010's | 51 (18.96) | 24.3611 |
| 2020's | 14 (5.20) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, L | 2 |
| Xi, Y | 1 |
| Wen, X | 1 |
| Zou, W | 1 |
| Hunie, M | 1 |
| Fenta, E | 1 |
| Kibret, S | 1 |
| Teshome, D | 1 |
| Robson, S | 1 |
| McParlin, C | 1 |
| Mossop, H | 1 |
| Lie, M | 1 |
| Fernandez-Garcia, C | 1 |
| Howel, D | 1 |
| Graham, R | 1 |
| Ternent, L | 1 |
| Steel, A | 1 |
| Goudie, N | 1 |
| Nadeem, A | 1 |
| Phillipson, J | 1 |
| Shehmar, M | 1 |
| Simpson, N | 1 |
| Tuffnell, D | 1 |
| Campbell, I | 1 |
| Williams, R | 1 |
| O'Hara, ME | 1 |
| McColl, E | 1 |
| Nelson-Piercy, C | 1 |
| Erdal, H | 1 |
| Holst, L | 2 |
| Heitmann, K | 2 |
| Trovik, J | 1 |
| Moosavi, S | 1 |
| Min, YW | 1 |
| Wong, M | 1 |
| Rezaie, A | 1 |
| Hamed, E | 1 |
| Hamza, WS | 1 |
| Farghaly, TA | 1 |
| Hamed, R | 1 |
| Tandon, M | 1 |
| Coudriet, GM | 1 |
| Criscimanna, A | 1 |
| Socorro, M | 1 |
| Eliliwi, M | 1 |
| Singhi, AD | 1 |
| Cruz-Monserrate, Z | 1 |
| Bailey, P | 1 |
| Lotze, MT | 1 |
| Zeh, H | 1 |
| Hu, J | 1 |
| Goffin, V | 1 |
| Gittes, GK | 1 |
| Biankin, AV | 1 |
| Esni, F | 1 |
| Kampo, S | 1 |
| Afful, AP | 1 |
| Mohammed, S | 1 |
| Ntim, M | 1 |
| Buunaaim, ADB | 1 |
| Anabah, TW | 1 |
| Ellaithy, M | 1 |
| Rasheed, S | 1 |
| Shafik, A | 1 |
| Abees, S | 1 |
| Bushman, ET | 1 |
| Cozzi, G | 1 |
| Sinkey, RG | 1 |
| Smith, CH | 1 |
| Varner, MW | 1 |
| Digre, K | 1 |
| Mathews, AT | 1 |
| Banks, CM | 1 |
| Trott, JF | 1 |
| Sainz, RD | 1 |
| Farmer, C | 1 |
| Pendergast, II | 1 |
| Hovey, RC | 1 |
| Cazorla-Ortiz, G | 1 |
| Obregón-Guitérrez, N | 1 |
| Rozas-Garcia, MR | 1 |
| Goberna-Tricas, J | 1 |
| Suarez, EA | 1 |
| Boggess, K | 1 |
| Engel, SM | 1 |
| Stürmer, T | 1 |
| Lund, JL | 1 |
| Jonsson Funk, M | 1 |
| Sakran, R | 1 |
| Shechtman, S | 1 |
| Arnon, J | 2 |
| Diav-Citrin, O | 1 |
| Hishinuma, K | 1 |
| Yamane, R | 1 |
| Yokoo, I | 1 |
| Arimoto, T | 1 |
| Takahashi, K | 1 |
| Goto, M | 1 |
| Saito, Y | 1 |
| Nakajima, K | 1 |
| Murashima, A | 1 |
| Hayashi, M | 1 |
| Negro, A | 1 |
| Verzicco, I | 1 |
| Tedeschi, S | 1 |
| Santi, R | 1 |
| Palladini, B | 1 |
| Calvi, A | 1 |
| Giunta, A | 1 |
| Cunzi, D | 1 |
| Coghi, P | 1 |
| Volpi, R | 1 |
| Cabassi, A | 1 |
| Luan, S | 1 |
| Mu, M | 1 |
| Tan, A | 1 |
| Lowe, S | 1 |
| Henry, A | 1 |
| Keller, SR | 1 |
| Abonyi-Tóth, Z | 1 |
| Sprenger, N | 1 |
| Austin, SC | 1 |
| Wichert, BAC | 1 |
| Liesegang, A | 1 |
| Oei, CHY | 1 |
| Balogh, O | 1 |
| Reichler, IM | 1 |
| Childress, KMS | 1 |
| Dothager, C | 1 |
| Gavard, JA | 1 |
| Lebovitz, S | 1 |
| Laska, C | 1 |
| Mostello, DJ | 1 |
| Hamilton, KT | 1 |
| Robbins, MS | 1 |
| Tabrizi, SO | 1 |
| Mirghafourvand, M | 1 |
| Dost, AJ | 1 |
| Mohammad-Alizadeh-Charandabi, S | 1 |
| Javadzadeh, Y | 1 |
| Seyedi, R | 1 |
| Havnen, GC | 1 |
| Truong, MB | 1 |
| Do, MH | 1 |
| Nordeng, H | 2 |
| Pessoa, TL | 1 |
| Clemente Junior, WS | 1 |
| Costa, TXD | 1 |
| Bezerra, PKDV | 1 |
| Martins, RR | 1 |
| Bérard, A | 2 |
| Sheehy, O | 1 |
| Gorgui, J | 1 |
| Zhao, JP | 1 |
| Soares de Moura, C | 1 |
| Bernatsky, S | 1 |
| Mohamed, F | 1 |
| Firas, D | 1 |
| Riadh, B | 1 |
| Walid, D | 1 |
| Lasaad, S | 1 |
| Abdelhamid, K | 1 |
| Habib, AS | 3 |
| George, RB | 1 |
| McKeen, DM | 1 |
| White, WD | 1 |
| Ituk, US | 1 |
| Megalla, SA | 1 |
| Allen, TK | 1 |
| Kashifard, M | 2 |
| Basirat, Z | 1 |
| Golsorkhtabar-Amiri, M | 1 |
| Moghaddamnia, A | 1 |
| Lehmann, AS | 1 |
| Renbarger, JL | 1 |
| McCormick, CL | 1 |
| Topletz, AR | 1 |
| Rouse, C | 1 |
| Haas, DM | 1 |
| Pasternak, B | 2 |
| Svanström, H | 2 |
| Mølgaard-Nielsen, D | 1 |
| Melbye, M | 1 |
| Hviid, A | 2 |
| Matok, I | 2 |
| Perlman, A | 1 |
| Hastoy, A | 1 |
| Lien Tran, P | 1 |
| Lakestani, O | 1 |
| Barau, G | 1 |
| Gérardin, P | 1 |
| Boukerrou, M | 1 |
| Paranjothy, S | 2 |
| Griffiths, JD | 2 |
| Broughton, HK | 2 |
| Gyte, GM | 2 |
| Brown, HC | 2 |
| Thomas, J | 2 |
| Vrachnis, N | 1 |
| Zygouris, D | 1 |
| Iliodromiti, Z | 1 |
| Tan, PC | 4 |
| Tang, YY | 1 |
| Du, Y | 1 |
| Ni, J | 1 |
| Ma, YS | 1 |
| Lin, XM | 1 |
| Zhou, J | 1 |
| Abas, MN | 1 |
| Azmi, N | 1 |
| Omar, SZ | 3 |
| Furyk, JS | 1 |
| Meek, R | 1 |
| McKenzie, S | 1 |
| Clark, SM | 1 |
| Dutta, E | 1 |
| Hankins, GD | 1 |
| Axelsson, PB | 1 |
| Bjerrum, F | 1 |
| Løkkegaard, EC | 1 |
| Agah, J | 1 |
| Baghani, R | 1 |
| Rakhshani, MH | 1 |
| Rad, A | 1 |
| Mayhall, EA | 1 |
| Gray, R | 1 |
| Lopes, V | 1 |
| Matteson, KA | 1 |
| Jarraya, A | 1 |
| Elleuch, S | 1 |
| Zouari, J | 1 |
| Trigui, K | 1 |
| Sofiene, A | 1 |
| Smaoui, M | 1 |
| Kolsi, K | 1 |
| Festin, M | 2 |
| Araujo, AS | 1 |
| Simões, Mde J | 1 |
| Verna, C | 1 |
| Simões, RS | 1 |
| Soares Júnior, JM | 1 |
| Baracat, EC | 2 |
| Gomes, RC | 1 |
| Çekmez, Y | 1 |
| Korkmaz, V | 1 |
| Çakır, A | 1 |
| Göçmen, A | 1 |
| Ergün, Y | 1 |
| Gülşen, S | 1 |
| Akpak, YK | 1 |
| Boelig, RC | 1 |
| Barton, SJ | 1 |
| Saccone, G | 1 |
| Kelly, AJ | 1 |
| Edwards, SJ | 1 |
| Berghella, V | 1 |
| Amundsen, S | 1 |
| Øvrebø, TG | 1 |
| Amble, NM | 1 |
| Poole, AC | 1 |
| Dragoman, MV | 1 |
| Grossman, D | 1 |
| Kapp, N | 1 |
| Huong, NM | 1 |
| Habib, N | 1 |
| Dung, DL | 1 |
| Tamang, A | 1 |
| Yow, CM | 1 |
| Lacasse, A | 1 |
| Lagoutte, A | 1 |
| Ferreira, E | 1 |
| Gorodischer, R | 1 |
| Koren, G | 1 |
| Sheiner, E | 1 |
| Wiznitzer, A | 1 |
| Levy, A | 1 |
| Prakash, S | 1 |
| Pramanik, V | 1 |
| Chellani, H | 1 |
| Salhan, S | 1 |
| Gogia, AR | 1 |
| Michel, ME | 1 |
| Alanio, E | 1 |
| Bois, E | 1 |
| Gavillon, N | 1 |
| Graesslin, O | 1 |
| Selbst, SM | 1 |
| Shahriari, A | 1 |
| Khooshideh, M | 1 |
| Heidari, MH | 1 |
| Khine, PP | 1 |
| Vallikkannu, N | 1 |
| Fujii, Y | 4 |
| Fife, S | 1 |
| Gill, P | 1 |
| Hopkins, M | 1 |
| Angello, C | 1 |
| Boswell, S | 1 |
| Nelson, KM | 1 |
| Klauser, CK | 1 |
| Fox, NS | 1 |
| Istwan, N | 1 |
| Rhea, D | 1 |
| Rebarber, A | 1 |
| Desch, C | 1 |
| Palmer, B | 1 |
| Saltzman, D | 1 |
| Kimura, M | 1 |
| Okamoto, T | 1 |
| Tsukagoshi, H | 1 |
| Sato, J | 1 |
| Saito, S | 1 |
| Orbach-Zinger, S | 1 |
| Paul-Keslin, L | 1 |
| Nichinson, E | 1 |
| Chinchuck, A | 1 |
| Nitke, S | 1 |
| Eidelman, LA | 1 |
| Mishriky, BM | 2 |
| Mohammadbeigi, R | 1 |
| Shahgeibi, S | 1 |
| Soufizadeh, N | 1 |
| Rezaiie, M | 1 |
| Farhadifar, F | 1 |
| Reichmann, JP | 1 |
| Kirkbride, MS | 1 |
| Raymond, SH | 1 |
| Abkowitz, JL | 1 |
| Schaison, G | 1 |
| Boulad, F | 1 |
| Brown, DL | 1 |
| Buchanan, GR | 1 |
| Johnson, CA | 1 |
| Murray, JC | 1 |
| Sabo, KM | 1 |
| Berkovitch, M | 2 |
| Mazzota, P | 1 |
| Greenberg, R | 1 |
| Elbirt, D | 2 |
| Addis, A | 2 |
| Schuler-Faccini, L | 2 |
| Merlob, P | 1 |
| Stahl, B | 1 |
| Magee, L | 1 |
| Moretti, M | 1 |
| Ornoy, A | 2 |
| Bsat, FA | 1 |
| Hoffman, DE | 1 |
| Seubert, DE | 1 |
| Numazaki, M | 2 |
| Lahlou, S | 1 |
| Interaminense, Lde F | 1 |
| Figueiredo, AF | 1 |
| Duarte, GP | 1 |
| Gokhale, SG | 1 |
| Panchakshari, MB | 1 |
| Lombardi, DG | 1 |
| Istwan, NB | 1 |
| Rhea, DJ | 1 |
| O'Brien, JM | 1 |
| Barton, JR | 1 |
| Hansen, WF | 1 |
| McAndrew, S | 1 |
| Harris, K | 1 |
| Zimmerman, MB | 1 |
| Imarengiaye, CO | 1 |
| Ekwere, IT | 1 |
| Neri, I | 1 |
| Allais, G | 1 |
| Schiapparelli, P | 1 |
| Blasi, I | 1 |
| Benedetto, C | 1 |
| Facchinetti, F | 1 |
| Richter, JE | 1 |
| Buscaglia, J | 1 |
| Faris, J | 1 |
| Panzan, MQ | 1 |
| Júnior, JM | 1 |
| da Motta, EL | 1 |
| Haapalainen, EF | 1 |
| de Jesus Simões, M | 1 |
| Baptista, HA | 1 |
| Haidar, MA | 1 |
| Bondok, RS | 1 |
| El Sharnouby, NM | 1 |
| Eid, HE | 1 |
| Abd Elmaksoud, AM | 1 |
| Reza, N | 1 |
| Ali, SM | 1 |
| Saeed, K | 1 |
| Abul-Qasim, A | 1 |
| Reza, TH | 1 |
| Nimmo, WS | 3 |
| Kauppila, A | 7 |
| Kivinen, S | 6 |
| Ylikorkala, O | 3 |
| Morgan, M | 1 |
| Guldager, H | 1 |
| Jensen, FM | 1 |
| Andersen, KH | 1 |
| Arnfred, I | 1 |
| de Gezelle, H | 1 |
| Ooghe, W | 1 |
| Thiery, M | 1 |
| Dhont, M | 1 |
| Bylsma-Howell, M | 2 |
| Riggs, KW | 6 |
| McMorland, GH | 5 |
| Rurak, DW | 6 |
| Ongley, R | 2 |
| McErlane, B | 2 |
| Price, JD | 2 |
| Axelson, JE | 6 |
| Levin, G | 1 |
| Fisher, RS | 1 |
| Arvela, P | 2 |
| Jouppila, R | 1 |
| Pakarinen, A | 1 |
| Pelkonen, O | 2 |
| Tuimala, R | 1 |
| Messinis, IE | 2 |
| Souvatzoglou, A | 2 |
| Vrontakis, M | 1 |
| Stefos, T | 2 |
| Charitopoulou, R | 1 |
| Lolis, DE | 2 |
| Berlin, CM | 1 |
| Kubota, T | 7 |
| Yaoi, Y | 4 |
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| Murphy, DF | 1 |
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| Robuschi, G | 3 |
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| Gnudi, A | 3 |
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| Pawlikowski, M | 1 |
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| Wyner, J | 2 |
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| Tucker, HS | 2 |
| Lankford, HV | 2 |
| Gardner, DF | 1 |
| Blackard, WG | 2 |
| de Rosa, G | 1 |
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| de Rosa, E | 1 |
| Satta, MA | 1 |
| Aiello, A | 1 |
| Makhoul, O | 1 |
| Pasargiklian, E | 1 |
| Grubb, SR | 1 |
| Wigand, JP | 1 |
| Taylon, A | 1 |
| Becker, DP | 1 |
| Lee, D | 1 |
| León, C | 1 |
| Milanés, BA | 1 |
| Tolino, A | 1 |
| Tedeschi, A | 1 |
| Farace, R | 1 |
| Granata, P | 1 |
| Pineda, G | 1 |
| Olmos, P | 1 |
| Fatone, M | 2 |
| Benassi, L | 1 |
| Foscolo, MS | 1 |
| Gualerzi, C | 1 |
| Braverman, LE | 1 |
| Dall'Aglio, E | 1 |
| Gardini, E | 1 |
| Foscolo, S | 1 |
| Shanmugasundaram, K | 1 |
| Jason, DA | 1 |
| Rao, PV | 1 |
| Elanchezhian, C | 1 |
| Lewis, PJ | 1 |
| Devenish, C | 1 |
| Kahn, C | 1 |
| Jadot, G | 1 |
| Bruguerolle, B | 1 |
| Bouyard, L | 1 |
| Fabregou-Bergier, P | 1 |
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| Fitzgerald, BP | 1 |
| Cunningham, FJ | 2 |
| Rodriguez-Arnao, MD | 1 |
| Weightman, DR | 1 |
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| Nielsen, GL | 1 |
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| Lazarus, L | 2 |
| Compton, P | 1 |
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| Tee, CS | 1 |
| Vengadasalam, D | 1 |
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| Xie, QW | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Propofol on Postoperative Nausea and Vomiting in Patients Undergoing Elective Cesarean Section Under Spinal Anesthesia.[NCT05071794] | Phase 4 | 60 participants (Actual) | Interventional | 2021-05-01 | Completed | ||
| Use of an Antiemetic to Shorten the Length of Labor in Nulliparous Women, Exploring a Potential Role of an Old Drug[NCT01937234] | Phase 4 | 250 participants (Actual) | Interventional | 2013-07-31 | Completed | ||
| Prevalence and Burden of Nausea and Vomiting in Pregnant Women in Switzerland: Survey Purity 2022[NCT06055192] | 200 participants (Anticipated) | Observational | 2023-09-30 | Not yet recruiting | |||
| Enhanced Recovery at Cesarean Birth to Improve Postoperative Outcomes and Reduce Postoperative Length of Stay[NCT02956616] | Phase 2 | 118 participants (Actual) | Interventional | 2017-09-01 | Completed | ||
| The Effect of Adding Metoclopramide and Ondansetron to a Prophylactic Phenylephrine Infusion for the Management of Nausea and Vomiting Associated With Spinal Anesthesia for Cesarean Section[NCT01216410] | 306 participants (Actual) | Interventional | 2008-12-31 | Completed | |||
| Is the Application of Scopolamine Patch With or Without Intra-operative Acupressure Point P6 Stimulation More Effective Than Intra-operative Acupressure Point P6 Stimulation Alone?[NCT02960113] | Phase 4 | 240 participants (Actual) | Interventional | 2016-05-31 | Completed | ||
| Comparison of Gastric Volumes by Gastric Ultrasound in Term Parturients Undergoing Scheduled Elective Cesarean Delivery With and Without Metoclopramide[NCT05033041] | Phase 4 | 72 participants (Anticipated) | Interventional | 2021-10-20 | Recruiting | ||
| A Pilot, Randomized, Double-blind, Placebo-controlled Trial of Promethazine for Treatment of Diabetic Gastroparesis.[NCT02130622] | Phase 2 | 3 participants (Actual) | Interventional | 2014-07-31 | Terminated (stopped due to Lack of recruitment) | ||
| Phase I/II, Open-Label Study to Determine Safety and Efficacy of Sotatercept (ACE-011) in Adults With Red Blood Cell Transfusion- Dependent Diamond Blackfan Anemia[NCT01464164] | Phase 1/Phase 2 | 19 participants (Actual) | Interventional | 2012-01-31 | Terminated (stopped due to Supporter terminated the study due to no active patients (secondary to travel restrictions due to COVID).) | ||
| The Use of Novel Therapies to Reconstitute Blood Cell Production and Promote Organ Performance Using Bone Marrow Failure as a Model: a Pilot, Phase I/II Study of the Amino Acid Leucine in the Treatment of Patients With Transfusion-Dependent Diamond Blackf[NCT01362595] | Phase 1/Phase 2 | 55 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| Metoclopramide to Improve Lactogenesis II in Diabetic Women: a Randomized Controlled Trial[NCT00477776] | Phase 3 | 160 participants (Anticipated) | Interventional | 2006-04-30 | Completed | ||
| Comparison of the Efficacy of Alginate-based Reflux Suppressant and Magnesium-aluminium Antacid Gel for Treatment of Heartburn in Pregnancy : A Randomized Double-Blind Controlled Trial[NCT02470117] | Phase 4 | 100 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| The Effect of Turkish Classical Music on Postpartum Pain and Anxiety in Women Who Delivered Via Cesarean Section[NCT04111575] | 126 participants (Actual) | Interventional | 2018-02-05 | Completed | |||
| Is Intra-operative Acupuncture Point P6 Stimulation as Effective as Traditional Pharmacotherapy in Reducing Nausea and Vomiting During Cesarean Section With Regional Anesthesia?[NCT02959840] | Phase 4 | 180 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of patients discharged on postoperative Day #2 (NCT02956616)
Timeframe: Until patient's day of hospital discharge or a maximum of one month from cesarean delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Enhanced Recovery | 5 |
| Routine Perioperative Care | 2 |
Postoperative Length of Hospital Stay in Hours from time of surgery (NCT02956616)
Timeframe: Until patient's day of hospital discharge or a maximum of one month from cesarean delivery
| Intervention | Hours (Median) |
|---|---|
| Enhanced Recovery | 73.58 |
| Routine Perioperative Care | 75.50 |
The amount of postoperative pain medication required for each patient in Morphine Milligram Equivalents (NCT02956616)
Timeframe: Until patient's day of hospital discharge or a maximum of one month from cesarean delivery
| Intervention | Morphine Milligram Equivalents (Mean) |
|---|---|
| Enhanced Recovery | 117.16 |
| Routine Perioperative Care | 119.38 |
All patients will be queried regarding whether breastfeeding was initiated after cesarean birth and how soon after birth (NCT02956616)
Timeframe: Until patient's day of hospital discharge or a maximum of one month from cesarean delivery
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Breastfeeding | Bottlefeeding | Both Breastfeeding and Bottlefeeding | |
| Enhanced Recovery | 39 | 4 | 15 |
| Routine Perioperative Care | 29 | 2 | 29 |
Comparison of intraoperative nausea and vomiting between the 3 groups. (NCT01216410)
Timeframe: Intraoperatively
| Intervention | participants (Number) |
|---|---|
| Combination Group | 23 |
| Metoclopramide | 31 |
| Phenylephrine Infusion | 49 |
The number of patients with systolic blood pressure decrease to less than 20 % of baseline intraoperatively (NCT01216410)
Timeframe: Intraoperatively
| Intervention | participants with SBP< 20 % baseline (Number) |
|---|---|
| Combination Group | 16 |
| Metoclopramide | 19 |
| Phenylephrine Infusion | 16 |
(NCT01216410)
Timeframe: 0-24 hrs
| Intervention | participants (Number) |
|---|---|
| Combination Group | 95 |
| Metoclopramide | 93 |
| Phenylephrine Infusion | 97 |
1=very satisfied, 2=somewhat satisfied, 3= neither satisfied nor dissatisfied, 4=somewhat dissatisfied, 5= very dissatisfied. Number of very satisfied subjects posted. (NCT01216410)
Timeframe: 24 h
| Intervention | participants (Number) |
|---|---|
| Combination Group | 94 |
| Metoclopramide | 85 |
| Phenylephrine Infusion | 87 |
(NCT01216410)
Timeframe: 0-2h, 2-6h, 6-24h
| Intervention | participants (Number) | ||
|---|---|---|---|
| 0-2 hrs PONV | 2-6 hrs PONV | 6-24 hrs PONV | |
| Combination Group | 20 | 28 | 22 |
| Metoclopramide | 33 | 35 | 26 |
| Phenylephrine Infusion | 39 | 41 | 22 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after eversion of the uterus. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: After eversion of the uterus until replacement of the uterus
| Intervention | units on a scale (Mean) |
|---|---|
| Scopolamine Patch | 1.28 |
| Acupressure Point P6 | 1.09 |
| Scopolamine Patch + Acupressure Point P6 | 1.40 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after replacement of the uterus. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: After replacement of the uterus and to the next 15 minutes
| Intervention | units on a scale (Mean) |
|---|---|
| Scopolamine Patch | 2.19 |
| Acupressure Point P6 | 2.19 |
| Scopolamine Patch + Acupressure Point P6 | 2.51 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) after the administration of the regional anesthesia medications. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: From administration of anaesthesia until eversion of uterus
| Intervention | units on a scale (Mean) |
|---|---|
| Scopolamine Patch | 2.71 |
| Acupressure Point P6 | 2.57 |
| Scopolamine Patch + Acupressure Point P6 | 2.84 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) upon arrival to the post-operative recovery room. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02960113)
Timeframe: 15 minutes after replacement of the uterus to arrival at post-anaesthesia care unit
| Intervention | units on a scale (Mean) |
|---|---|
| Scopolamine Patch | 0.18 |
| Acupressure Point P6 | 0.25 |
| Scopolamine Patch + Acupressure Point P6 | 0.23 |
The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea at any point during the surgical procedure in each group. (NCT02960113)
Timeframe: Throughout the entire surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 40 |
| Acupressure Point P6 | 39 |
| Scopolamine Patch + Acupressure Point P6 | 46 |
The investigators will perform objective assessments of whether or not the patients have vomited during the procedure. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: Throughout the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 24 |
| Acupressure Point P6 | 25 |
| Scopolamine Patch + Acupressure Point P6 | 31 |
Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: After eversion of to replacement of the uterus
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 8 |
| Acupressure Point P6 | 6 |
| Scopolamine Patch + Acupressure Point P6 | 9 |
Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: After replacement of the uterus and for next 15 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 10 |
| Acupressure Point P6 | 15 |
| Scopolamine Patch + Acupressure Point P6 | 12 |
Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: After the administration of the regional anesthesia medications until eversion of the uterus
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 20 |
| Acupressure Point P6 | 15 |
| Scopolamine Patch + Acupressure Point P6 | 20 |
Objective assessments of whether or not the patients have vomited at this point in the surgical procedure will be done. The investigators will analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02960113)
Timeframe: From 15 minutes after replacement of the uterus until arrival at the post-anaesthesia care unit
| Intervention | Participants (Count of Participants) |
|---|---|
| Scopolamine Patch | 1 |
| Acupressure Point P6 | 1 |
| Scopolamine Patch + Acupressure Point P6 | 4 |
Patients are asked their nausea and vomiting treatment satisfaction (0 = Not Satisfied, 10 = Extremely Satisfied). Patients are also asked their overall satisfaction with the procedure (0 = Not Satisfied, 10 = Extremely Satisfied). (NCT02960113)
Timeframe: Throughout the surgical procedure
| Intervention | units on a scale (Mean) |
|---|---|
| Scopolamine Patch | 9.29 |
| Acupressure Point P6 | 8.96 |
| Scopolamine Patch + Acupressure Point P6 | 9.59 |
Complete response is transfusion independence with hemoglobin >9 gm/dl; partial response is transfusion dependence with hemoglobin < 9gm/dl with an increase in reticulocyte count over baseline (NCT01464164)
Timeframe: 9 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Sotatercept Cohort 1 | 0 |
| Sotatercept Cohort 2 | 0 |
| Sotatercept Cohort 3 | 0 |
| Sotatercept With Prednisone Boost Cohort 4a | 0 |
| Sotatercept Cohort 4b | 0 |
| Sotatercept With Prednisone Boost Cohort 5a | 0 |
| Sotatercept Cohort 5b | 0 |
Assess severity of adverse events and relationship to sotatercept according to the currently active minor version of the NCI Common Terminology for Adverse Events version 4.0 (NCT01464164)
Timeframe: 9 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Sotatercept Cohort 1 | 0 |
| Sotatercept Cohort 2 | 0 |
| Sotatercept Cohort 3 | 0 |
| Sotatercept With Prednisone Boost Cohort 4a | 0 |
| Sotatercept Cohort 4b | 0 |
| Sotatercept With Prednisone Boost Cohort 5a | 0 |
| Sotatercept Cohort 5b | 0 |
"The primary outcome is the type of response observed at 9 months. Response to treatment can be one of the following:~Complete response (CR): Hb > 9 gm/dL and transfusion-independence as defined in DBA~Partial response (PR): Hb < 9 gm/dL and increased reticulocyte count to greater than baseline.~No response (NR): no change in transfusion requirements and no significant change reticulocyte count from baseline~Progression: worsening of disease as defined by the need for more frequent transfusions" (NCT01362595)
Timeframe: 9 Months
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Complete Hematologic Response | Partial hematologic response | No hematologic response | Progression | |
| Leucine | 2 | 5 | 36 | 0 |
The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea at any point during the surgical procedure in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 44 |
| Metoclopramide, Ondansetron | 14 |
| Acupressure Point P6 Stimulator | 22 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) during stage I. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 33 |
| Metoclopramide, Ondansetron | 7 |
| Acupressure Point P6 Stimulator | 14 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) during stage II. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 12 |
| Metoclopramide, Ondansetron | 6 |
| Acupressure Point P6 Stimulator | 5 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) during stage III. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 16 |
| Metoclopramide, Ondansetron | 8 |
| Acupressure Point P6 Stimulator | 14 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) during stage IV. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 3 |
| Metoclopramide, Ondansetron | 4 |
| Acupressure Point P6 Stimulator | 0 |
Patients are asked their overall anesthetic care satisfaction (0 = Not Satisfied, 10 = Extremely Satisfied). Data are expressed as number of parturients who gave a score of 8 or higher. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 53 |
| Metoclopramide, Ondansetron | 58 |
| Acupressure Point P6 Stimulator | 56 |
Patients are asked their anti-emetic treatment satisfaction (0 = Not Satisfied, 10 = Extremely Satisfied). Data are expressed as number of parturients who gave a score of 8 or higher. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 49 |
| Metoclopramide, Ondansetron | 58 |
| Acupressure Point P6 Stimulator | 55 |
The investigators will perform objective assessments of whether or not the patients have vomited during the procedure. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 27 |
| Metoclopramide, Ondansetron | 10 |
| Acupressure Point P6 Stimulator | 8 |
The investigators will perform objective assessments of whether or not the patients have vomited during stage I. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 20 |
| Metoclopramide, Ondansetron | 5 |
| Acupressure Point P6 Stimulator | 4 |
The investigators will perform objective assessments of whether or not the patients have vomited during stage II. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 10 |
| Metoclopramide, Ondansetron | 1 |
| Acupressure Point P6 Stimulator | 3 |
The investigators will perform objective assessments of whether or not the patients have vomited during stage III. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 9 |
| Metoclopramide, Ondansetron | 4 |
| Acupressure Point P6 Stimulator | 6 |
The investigators will perform objective assessments of whether or not the patients have vomited during stage IV. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 0 |
| Metoclopramide, Ondansetron | 2 |
| Acupressure Point P6 Stimulator | 0 |
24 reviews available for metoclopramide and Pregnancy
| Article | Year |
|---|---|
Use of metoclopramide in the first trimester and risk of major congenital malformations: A systematic review and meta-analysis.
Topics: Antiemetics; Congenital Abnormalities; Female; Humans; Metoclopramide; Nausea; Odds Ratio; Pregnancy | 2021 |
Gastroparesis in pregnancy.
Topics: Female; Gastrointestinal Agents; Gastroparesis; Humans; Metoclopramide; Pregnancy | 2023 |
Randomized Controlled Trials of Headache Treatments in Pregnancy: A Systematic Review.
Topics: Acupuncture Analgesia; Analgesics; Biofeedback, Psychology; Codeine; Complementary Therapies; Diphen | 2021 |
Methods and Success Factors of Induced Lactation: A Scoping Review.
Topics: Adult; Breast Feeding; Dopamine D2 Receptor Antagonists; Female; Galactorrhea; Humans; Lactation; Me | 2020 |
Interventions at caesarean section for reducing the risk of aspiration pneumonitis.
Topics: Anesthesia, General; Anesthesia, Obstetrical; Antacids; Antiemetics; Cesarean Section; Drug Therapy, | 2014 |
The outpatient management and special considerations of nausea and vomiting in pregnancy.
Topics: Ambulatory Care; Antiemetics; Diet Therapy; Doxylamine; Female; Fluid Therapy; Gastroesophageal Refl | 2014 |
[Pharmaceutical treatment of lactation deficiency lacks evidence].
Topics: Breast Feeding; Domperidone; Dopamine Antagonists; Evidence-Based Medicine; Female; Humans; Lactatio | 2014 |
Interventions for treating hyperemesis gravidarum.
Topics: Acupuncture Therapy; Adrenal Cortex Hormones; Antiemetics; Female; Humans; Hydrocortisone; Hyperemes | 2016 |
Interventions at caesarean section for reducing the risk of aspiration pneumonitis.
Topics: Anesthesia, General; Anesthesia, Obstetrical; Antacids; Antiemetics; Cesarean Section; Drug Therapy, | 2010 |
Prevention of nausea and vomiting during termination of pregnancy.
Topics: Abortion, Therapeutic; Antiemetics; Benzimidazoles; Dexamethasone; Dilatation and Curettage; Droperi | 2010 |
Nausea and vomiting in early pregnancy.
Topics: Acupressure; Administration, Oral; Domperidone; Female; Humans; Metoclopramide; Nausea; Phytotherapy | 2009 |
Metoclopramide for nausea and vomiting prophylaxis during and after Caesarean delivery: a systematic review and meta-analysis.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Antiemetics; Cesarean Section; Female; Humans; Intr | 2012 |
Reviewing the evidence for using continuous subcutaneous metoclopramide and ondansetron to treat nausea & vomiting during pregnancy.
Topics: Antiemetics; Evidence-Based Medicine; Female; Humans; Infusions, Subcutaneous; Metoclopramide; Nause | 2012 |
Review article: the management of heartburn in pregnancy.
Topics: Antacids; Anti-Ulcer Agents; Cisapride; Female; Gastroesophageal Reflux; Gastrointestinal Motility; | 2005 |
Control of intragastric pH and volume.
Topics: Anesthesia, General; Animals; Antacids; Apomorphine; Benzimidazoles; Child; Female; Gastric Acid; Ga | 1984 |
Gastroesophageal reflux disease: an update.
Topics: Antacids; Anti-Ulcer Agents; Bethanechol Compounds; Domperidone; Female; Gastroesophageal Reflux; Hu | 1983 |
Advances in pediatric pharmacology and toxicology.
Topics: Animals; Anti-Bacterial Agents; Aspirin; Attention Deficit Disorder with Hyperactivity; Biological A | 1983 |
New approaches for drug and kinetic analysis in the maternal-fetal unit.
Topics: Animals; Diphenhydramine; Female; Fetus; Labetalol; Metoclopramide; Pregnancy; Pregnancy, Animal; Sh | 1995 |
[Evaluation and treatment of hyperemesis gravidarum].
Topics: Administration, Oral; Adult; Antiemetics; Birth Weight; Chlorpromazine; Diagnosis, Differential; Fem | 2001 |
The diagnosis and management of gastroesophageal reflux.
Topics: Bethanechol Compounds; Clinical Trials as Topic; Esophagogastric Junction; Female; Gastroesophageal | 1976 |
Metoclopramide: a review of its pharmacological properties and clinical use.
Topics: Animals; Basal Ganglia Diseases; Cardiovascular System; Central Nervous System; Clinical Trials as T | 1976 |
The use of gastrointestinal drugs during pregnancy and lactation.
Topics: Adrenal Cortex Hormones; Animals; Antidiarrheals; Antiemetics; Cathartics; Diuretics; Female; Gastro | 1985 |
Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy.
Topics: Antiemetics; Antipsychotic Agents; Dicyclomine; Diphenhydramine; Doxylamine; Drug Combinations; Fema | 1986 |
Metoclopramide--a review.
Topics: Anxiety; Digestive System; Dopamine Antagonists; Drug Interactions; Female; Gastric Emptying; Gastro | 1986 |
68 trials available for metoclopramide and Pregnancy
| Article | Year |
|---|---|
Ondansetron and metoclopramide as second-line antiemetics in women with nausea and vomiting in pregnancy: the EMPOWER pilot factorial RCT.
Topics: Antiemetics; Cost-Benefit Analysis; Female; Humans; Metoclopramide; Nausea; Ondansetron; Pregnancy; | 2021 |
Ultrasonographic assessment of metoclopramide effect on gastric volume in parturients females undergoing Caesarean section: a randomized double blind study.
Topics: Cesarean Section; Double-Blind Method; Female; Humans; Metoclopramide; Postoperative Nausea and Vomi | 2023 |
Sub-hypnotic dose of propofol as antiemetic prophylaxis attenuates intrathecal morphine-induced postoperative nausea and vomiting, and pruritus in parturient undergoing cesarean section - a randomized control trial.
Topics: Adult; Analgesics, Opioid; Antiemetics; Cesarean Section; Dose-Response Relationship, Drug; Double-B | 2019 |
Use of an antiemetic to shorten the length of labor in nulliparous women, exploring a potential role of an old drug: A randomized controlled trial.
Topics: Administration, Intravenous; Adult; Antiemetics; Double-Blind Method; Female; Humans; Labor Stage, F | 2020 |
Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study).
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Codeine; Diphenhydramine; Double-Blind Method; Drug A | 2018 |
Effect of metoclopramide administration to mothers on neonatal bilirubin and maternal prolactin: a randomized, controlled, clinical trial.
Topics: Blood Chemical Analysis; Breast Feeding; Chi-Square Distribution; Double-Blind Method; Female; Follo | 2019 |
Antiemetics added to phenylephrine infusion during cesarean delivery: a randomized controlled trial.
Topics: Adult; Anesthesia, Spinal; Antiemetics; Cardiotonic Agents; Cesarean Section; Drug Therapy, Combinat | 2013 |
Antiemetics added to phenylephrine infusion during cesarean delivery: a randomized controlled trial.
Topics: Adult; Anesthesia, Spinal; Antiemetics; Cardiotonic Agents; Cesarean Section; Drug Therapy, Combinat | 2013 |
Antiemetics added to phenylephrine infusion during cesarean delivery: a randomized controlled trial.
Topics: Adult; Anesthesia, Spinal; Antiemetics; Cardiotonic Agents; Cesarean Section; Drug Therapy, Combinat | 2013 |
Antiemetics added to phenylephrine infusion during cesarean delivery: a randomized controlled trial.
Topics: Adult; Anesthesia, Spinal; Antiemetics; Cardiotonic Agents; Cesarean Section; Drug Therapy, Combinat | 2013 |
Ondansetrone or metoclopromide? Which is more effective in severe nausea and vomiting of pregnancy? A randomized trial double-blind study.
Topics: Adult; Antiemetics; Double-Blind Method; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Ond | 2013 |
Ondansetron compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial.
Topics: Adult; Antiemetics; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Ondansetron; Pregnancy; | 2014 |
Metoclopramide role in preventing ileus after cesarean, a clinical trial.
Topics: Adult; Cesarean Section; Female; Humans; Ileus; Metoclopramide; Pregnancy | 2015 |
Two prophylactic medication approaches in addition to a pain control regimen for early medical abortion < 63 days' gestation with mifepristone and misoprostol: study protocol for a randomized, controlled trial.
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Adolescent; | 2016 |
A placebo-controlled trial of oral pyridoxine in hyperemesis gravidarum.
Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramid | 2009 |
Maternal and neonatal effects of bolus administration of ephedrine and phenylephrine during spinal anaesthesia for caesarean delivery: a randomised study.
Topics: Acid-Base Equilibrium; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anti-Ulcer Agents; Antiem | 2010 |
Prevention of nausea and vomiting in caesarean section under spinal anaesthesia with midazolam or metoclopramide?
Topics: Adolescent; Adult; Anesthesia, Spinal; Antiemetics; Cesarean Section; Chi-Square Distribution; Doubl | 2009 |
Promethazine compared with metoclopramide for hyperemesis gravidarum: a randomized controlled trial.
Topics: Adult; Antiemetics; Double-Blind Method; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Pre | 2010 |
Metoclopramide to augment lactation, does it work? A randomized trial.
Topics: Adult; Double-Blind Method; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Lac | 2011 |
Effect of flurbiprofen, metoclopramide and droperidol for nausea and emesis during cesarean section under spinal anesthesia.
Topics: Adjuvants, Anesthesia; Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Anesthesia, Spinal; Ant | 2011 |
Tramadol-metoclopramide or remifentanil for patient-controlled analgesia during second trimester abortion: a double-blinded, randomized controlled trial.
Topics: Abortion, Induced; Academic Medical Centers; Adult; Analgesia, Patient-Controlled; Analgesics, Opioi | 2012 |
Comparing the effects of ginger and metoclopramide on the treatment of pregnancy nausea.
Topics: Adult; Antiemetics; Double-Blind Method; Female; Humans; Metoclopramide; Nausea; Placebos; Pregnancy | 2011 |
Response of Diamond-Blackfan anemia to metoclopramide: evidence for a role for prolactin in erythropoiesis.
Topics: Anemia, Diamond-Blackfan; Erythropoiesis; Female; Humans; Metoclopramide; Middle Aged; Pilot Project | 2002 |
Response of Diamond-Blackfan anemia to metoclopramide: evidence for a role for prolactin in erythropoiesis.
Topics: Anemia, Diamond-Blackfan; Erythropoiesis; Female; Humans; Metoclopramide; Middle Aged; Pilot Project | 2002 |
Response of Diamond-Blackfan anemia to metoclopramide: evidence for a role for prolactin in erythropoiesis.
Topics: Anemia, Diamond-Blackfan; Erythropoiesis; Female; Humans; Metoclopramide; Middle Aged; Pilot Project | 2002 |
Response of Diamond-Blackfan anemia to metoclopramide: evidence for a role for prolactin in erythropoiesis.
Topics: Anemia, Diamond-Blackfan; Erythropoiesis; Female; Humans; Metoclopramide; Middle Aged; Pilot Project | 2002 |
Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy.
Topics: Adult; Antiemetics; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramid | 2003 |
Reduction of emetic symptoms during cesarean delivery with antiemetics: propofol at subhypnotic dose versus traditional antiemetics.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Double-Blind Meth | 2003 |
Metoclopramide effect on breastfeeding the preterm infant: a randomized trial.
Topics: Adult; Breast Feeding; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Sc | 2005 |
Acupuncture versus pharmacological approach to reduce Hyperemesis gravidarum discomfort.
Topics: Acupressure; Administration, Oral; Adult; Antiemetics; Chi-Square Distribution; Drug Therapy, Combin | 2005 |
Pulsed steroid therapy is an effective treatment for intractable hyperemesis gravidarum.
Topics: Adult; Anti-Inflammatory Agents; Antiemetics; Double-Blind Method; Female; Humans; Hydrocortisone; H | 2006 |
The impact of music on postoperative pain and anxiety following cesarean section.
Topics: Adult; Analgesics, Opioid; Anesthesia, General; Anti-Anxiety Agents; Antiemetics; Anxiety; Cesarean | 2007 |
A dose response relation between improved lactation and metoclopramide.
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Lac | 1981 |
[Domperidone and metoclopramide in the prevention of postoperative nausea and vomiting].
Topics: Abortion, Induced; Adolescent; Adult; Clinical Trials as Topic; Domperidone; Double-Blind Method; Fe | 1983 |
Metoclopramide and breast milk.
Topics: Amino Acids; Clinical Trials as Topic; Double-Blind Method; Fatty Acids; Female; Humans; Lactation; | 1983 |
Placental transport of metoclopramide: assessment of maternal and neonatal effects.
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Apgar Score; Cesarean Section; Clinical Trials | 1983 |
Relationships between serum prolactin levels and follicle stimulating hormone response to luteinizing hormone-releasing hormone during early puerperium.
Topics: Adult; Bromocriptine; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; | 1983 |
Effect of metoclopramide on gastric emptying before elective and emergency caesarean section.
Topics: Acetaminophen; Adult; Cesarean Section; Emergencies; Female; Gastric Emptying; Humans; Labor, Obstet | 1984 |
Vomiting after anaesthesia for termination of pregnancy in Chinese.
Topics: Abortion, Induced; Anesthesia, Obstetrical; China; Ethnicity; Female; Humans; Metoclopramide; Preane | 1983 |
Controlled trial of metoclopramide in the initiation of breast feeding.
Topics: Breast Feeding; Clinical Trials as Topic; Female; Humans; Lactation; Metoclopramide; Milk, Human; Pl | 1980 |
Ovarian and placental hormones during prolactin suppression and stimulation in early human pregnancy.
Topics: Adult; Bromocriptine; Estradiol; Female; Humans; Metoclopramide; Placental Hormones; Pregnancy; Preg | 1980 |
Evaluation of two antiemetic agents during outpatient gynaecological surgery.
Topics: Abortion, Induced; Adult; Ambulatory Surgical Procedures; Analysis of Variance; Anesthesia, General; | 1994 |
[Drug induced prevention of the acid aspiration syndrome in non-elective cesarean section].
Topics: Cesarean Section; Citrates; Citric Acid; Famotidine; Female; Humans; Metoclopramide; Pneumonia, Aspi | 1994 |
Intrathecal meperidine for elective caesarean section: a comparison with lidocaine.
Topics: Adult; Analgesia, Obstetrical; Anesthesia, Epidural; Apgar Score; Cesarean Section; Female; Humans; | 1993 |
Effects of omeprazole, with and without metoclopramide, in elective obstetric anaesthesia.
Topics: Administration, Oral; Adult; Anesthesia, Obstetrical; Cesarean Section; Double-Blind Method; Drug Th | 1993 |
Tiapride versus metoclopramide: comparison after minor gynaecological surgery.
Topics: Abortion, Incomplete; Abortion, Missed; Adolescent; Adult; Dilatation and Curettage; Double-Blind Me | 1993 |
Bolus metoclopramide does not enhance morphine analgesia after cesarean section.
Topics: Acetylcholine; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Obstetrical; Anesthesi | 1996 |
Acid aspiration prophylaxis for emergency Caesarean section.
Topics: Adult; Antacids; Anti-Ulcer Agents; Cesarean Section; Citrates; Citric Acid; Drug Therapy, Combinati | 1996 |
Acupressure versus intravenous metoclopramide to prevent nausea and vomiting during spinal anesthesia for cesarean section.
Topics: Acupressure; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Doub | 1997 |
Ondansetron is not superior to moderate dose metoclopramide in the prevention of post-operative nausea and vomiting after minor gynaecological surgery.
Topics: Adult; Antiemetics; Dilatation and Curettage; Double-Blind Method; Female; Gynecologic Surgical Proc | 1997 |
Prevention of nausea and vomiting with granisetron, droperidol and metoclopramide during and after spinal anaesthesia for caesarean section: a randomized, double-blind, placebo-controlled trial.
Topics: Adult; Anesthesia, Spinal; Antiemetics; Cesarean Section; Double-Blind Method; Droperidol; Female; G | 1998 |
Subhypnotic dose of propofol for the prevention of nausea and vomiting during spinal anaesthesia for caesarean section.
Topics: Adult; Analysis of Variance; Anesthesia, Obstetrical; Anesthesia, Spinal; Anesthetics, Intravenous; | 2000 |
A comparison of antiemetic efficacy of droperidol alone and in combination with metoclopramide in day surgery anaesthesia.
Topics: Adult; Ambulatory Surgical Procedures; Antiemetics; Droperidol; Drug Therapy, Combination; Female; H | 1997 |
Comparing the efficacy of prophylactic metoclopramide, ondansetron, and placebo in cesarean section patients given epidural anesthesia.
Topics: Adult; Anesthesia, Epidural; Anesthesia, Obstetrical; Antiemetics; Cesarean Section; Double-Blind Me | 2001 |
Metoclopramide and the gastro-oesophageal sphincter. A study in pregnant women with heartburn.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Esophagogastric Junction; Female; | 1978 |
Improvement of defective lactation by using oral metoclopramide.
Topics: Administration, Oral; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Lactation Disorders | 1979 |
The diagnosis and management of gastroesophageal reflux.
Topics: Bethanechol Compounds; Clinical Trials as Topic; Esophagogastric Junction; Female; Gastroesophageal | 1976 |
Metoclopramide: a review of its pharmacological properties and clinical use.
Topics: Animals; Basal Ganglia Diseases; Cardiovascular System; Central Nervous System; Clinical Trials as T | 1976 |
Ondansetron in the treatment of postoperative vomiting: a randomized, double-blind comparison with droperidol and metoclopramide.
Topics: Adult; Anesthesia, General; Anesthesia, Obstetrical; Antiemetics; Dilatation and Curettage; Double-B | 1992 |
Metoclopramide-enhanced analgesia for prostaglandin-induced termination of pregnancy.
Topics: Abortion, Induced; Adult; Analgesia, Obstetrical; Female; Humans; Labor, Induced; Metoclopramide; Mo | 1992 |
[Value of the metoclopramide test in diagnosis of hormonal causes of female sterility].
Topics: Adult; Bromocriptine; Female; Gonadal Steroid Hormones; Humans; Hyperprolactinemia; Infertility, Fem | 1992 |
[Pharmacologic prevention of Mendelson syndrome. A controlled clinical trial].
Topics: Adult; Anesthesia, Obstetrical; Cesarean Section; Drug Therapy, Combination; Female; Gastric Acidity | 1992 |
Nausea and vomiting after termination of pregnancy as day surgery cases: comparison of 3 different doses of droperidol and metoclopramide as anti-emetic prophylaxis.
Topics: Abortion, Induced; Adult; Ambulatory Surgical Procedures; Dose-Response Relationship, Drug; Droperid | 1991 |
Metoclopramide: an analgesic adjunct to patient-controlled analgesia.
Topics: Abortion, Induced; Adult; Analgesia, Patient-Controlled; Double-Blind Method; Female; Humans; Labor, | 1991 |
Dose-dependent effect of metoclopramide on cholinesterases and suxamethonium metabolism.
Topics: Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Erythrocytes; Female | 1990 |
Neuromuscular block by suxamethonium following treatment with histamine type 2 antagonists or metoclopramide.
Topics: Clinical Trials as Topic; Drug Synergism; Female; Histamine H2 Antagonists; Humans; Metoclopramide; | 1989 |
The effect of magnesium trisilicate mixture, metoclopramide and ranitidine on gastric pH, volume and serum gastrin.
Topics: Adult; Antacids; Drug Therapy, Combination; Female; Gastrins; Humans; Hydrogen-Ion Concentration; Ma | 1985 |
[The effect of metoclopramide on postoperative nausea and vomiting].
Topics: Abortion, Therapeutic; Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hum | 1988 |
[Management of lactation deficiency in the immediate postpartum period].
Topics: Antidepressive Agents; Clinical Trials as Topic; Female; Humans; Lactation; Lactation Disorders; Met | 1986 |
Metoclopramide and breast feeding: efficacy and anterior pituitary responses of the mother and the child.
Topics: Adult; Breast Feeding; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infant; Lactat | 1985 |
The evaluation of domperidone and metoclopramide as antiemetics in day care abortion patients.
Topics: Abortion, Therapeutic; Adolescent; Adult; Anesthesia, General; Anesthesia, Obstetrical; Clinical Tri | 1985 |
Comparison of the antiemetics metoclopramide and promethazine in labour.
Topics: Clinical Trials as Topic; Consciousness; Double-Blind Method; Female; Humans; Meperidine; Metoclopra | 1985 |
The effect of intra-muscular metoclopramide on gastric emptying during labour.
Topics: Anesthesia, Obstetrical; Clinical Trials as Topic; Female; Gastrointestinal Motility; Humans; Inject | 1973 |
The anti-emetic effect of metoclopramide with an account of some experiments to assess the effect of the drug on gastric emptying in early labour.
Topics: Anesthesia, Obstetrical; Female; Gastrointestinal Motility; Humans; Inhalation; Labor, Obstetric; Me | 1973 |
179 other studies available for metoclopramide and Pregnancy
| Article | Year |
|---|---|
The current practice of aspiration prophylaxis in obstetric anesthesia: a survey among non-physician anesthetic providers working in hospitals in Ethiopia.
Topics: Adult; Anesthesia, Conduction; Anesthesia, Obstetrical; Antiemetics; Cesarean Section; Ethiopia; Fem | 2021 |
Antiemetic treatment of hyperemesis gravidarum in 1,064 Norwegian women and the impact of European warning on metoclopramide: a retrospective cohort study 2002-2019.
Topics: Antiemetics; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Pregnancy; Quality of Life; Ret | 2022 |
Prolactin Promotes Fibrosis and Pancreatic Cancer Progression.
Topics: Animals; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Collagen; Disease Progression; Epithelium; | 2019 |
Metoclopramide induces preparturient, low-level hyperprolactinemia to increase milk production in primiparous sows.
Topics: Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Body Weight; Dopamine D2 Rece | 2021 |
Ondansetron use in early pregnancy and the risk of miscarriage.
Topics: Abortion, Spontaneous; Antiemetics; Female; Humans; Metoclopramide; Ondansetron; Pregnancy; Vomiting | 2021 |
Pregnancy outcome following in-utero exposure to ondansetron: A prospective comparative observational study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Antiemetics; Child; Child, Preschool; Female; Heart | 2021 |
Pregnancy outcome after first trimester exposure to domperidone-An observational cohort study.
Topics: Cohort Studies; Domperidone; Female; Humans; Metoclopramide; Pregnancy; Pregnancy Outcome; Pregnancy | 2021 |
Unrecognised pheochromocytoma in pregnancy discovered through metoclopramide-triggered hypertensive emergency.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cesarean Section; Female; Humans; Hypertension; Infan | 2021 |
The mechanism of selfheal extract in treating hyperprolactinemia.
Topics: Animals; Cell Line; Dopamine Plasma Membrane Transport Proteins; Drugs, Chinese Herbal; Female; Horm | 2017 |
Nausea and vomiting of pregnancy: Effects on quality of life and day-to-day function.
Topics: Activities of Daily Living; Antiemetics; Cohort Studies; Female; Humans; Hyperemesis Gravidarum; Met | 2018 |
Effect of metoclopramide treatment of bitches during the first week of lactation on serum prolactin concentration, milk composition, and milk yield and on weight gain of their puppies.
Topics: Animals; Animals, Newborn; Dogs; Female; Lactation; Lactose; Metoclopramide; Milk; Parturition; Preg | 2018 |
Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study.
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Diphenhydramine; Drug Therapy, Combination; Female; H | 2019 |
Women's perspectives on the management and consequences of hyperemesis gravidarum - a descriptive interview study.
Topics: Abortion, Induced; Activities of Daily Living; Adult; Antiemetics; Attitude; Cross-Sectional Studies | 2019 |
Drug interactions in maternal intensive care: prevalence, risk factors, and potential risk medications.
Topics: Adolescent; Adult; Brazil; Cross-Sectional Studies; Diazepam; Drug Interactions; Drug-Related Side E | 2019 |
New evidence for concern over the risk of birth defects from medications for nausea and vomitting of pregnancy.
Topics: Abnormalities, Drug-Induced; Adult; Antiemetics; Cohort Studies; Dicyclomine; Doxylamine; Drug Combi | 2019 |
Combined use of metoclopramide and dexamethasone as a prophylactic antiemetic in elective cesarean section under spinal anesthesia.
Topics: Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Dexamethasone; Drug Therapy, Combin | 2012 |
Pharmacogenetic predictors of nausea and vomiting of pregnancy severity and response to antiemetic therapy: a pilot study.
Topics: Adult; Antiemetics; Female; Humans; Metoclopramide; Morning Sickness; Ondansetron; Pilot Projects; P | 2013 |
Metoclopramide in pregnancy and risk of major congenital malformations and fetal death.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Antiemetics; Case-Control Studies; Denmar | 2013 |
Metoclopramide in pregnancy: no association with adverse fetal and neonatal outcomes.
Topics: Abnormalities, Drug-Induced; Antiemetics; Female; Fetal Death; Humans; Metoclopramide; Pregnancy | 2014 |
[Hyperemesis gravidarum and pregnancy outcomes].
Topics: Adult; Antiemetics; Female; Hospitalization; Humans; Hyperemesis Gravidarum; Infant, Newborn; Metocl | 2015 |
Fetal outcomes associated with metoclopramide use in pregnancy.
Topics: Abnormalities, Drug-Induced; Antiemetics; Female; Fetal Death; Humans; Metoclopramide; Pregnancy | 2014 |
Fetal outcomes associated with metoclopramide use in pregnancy--reply.
Topics: Abnormalities, Drug-Induced; Antiemetics; Female; Fetal Death; Humans; Metoclopramide; Pregnancy | 2014 |
ACP Journal Club. Metoclopramide during pregnancy did not increase risk for major congenital malformations or fetal death.
Topics: Abnormalities, Drug-Induced; Antiemetics; Female; Fetal Death; Humans; Metoclopramide; Pregnancy | 2014 |
Relaxant effects of metoclopramide and magnesium sulfate on isolated pregnant myometrium: an in vitro study.
Topics: Adult; Cabergoline; Dopamine Agonists; Dopamine Antagonists; Ergolines; Female; Humans; In Vitro Tec | 2014 |
Drug treatment of adults with nausea and vomiting in primary care.
Topics: Adult; Antiemetics; Domperidone; Droperidol; Female; Histamine Antagonists; Humans; Male; Metoclopra | 2014 |
Comparison of antiemetics for nausea and vomiting of pregnancy in an emergency department setting.
Topics: Adult; Antiemetics; Cohort Studies; Emergency Service, Hospital; Female; Humans; Hypotension, Orthos | 2015 |
[Hyperemesis gravidarum with severe electrolyte disorders: report of a case].
Topics: Acute Kidney Injury; Antiemetics; Female; Fluid Therapy; Hepatomegaly; Humans; Hyperemesis Gravidaru | 2015 |
Nausea and Vomiting in Early Pregnancy.
Topics: Acupuncture; Antiemetics; Female; Humans; Hydrocortisone; Hyperemesis Gravidarum; Metoclopramide; Mo | 2015 |
Influence of hyperprolactinemia on collagen fibers in the lacrimal gland of female mice.
Topics: Animals; Collagen; Estradiol; Female; Hyperprolactinemia; Lacrimal Apparatus; Metoclopramide; Mice; | 2015 |
Does metoclopramide exposure alter endometrial receptivity and decrease pregnancy rates?
Topics: Animals; Embryo Implantation; Endometrium; Female; Immunohistochemistry; Integrin beta3; Metoclopram | 2016 |
Use of antimigraine medications and information needs during pregnancy and breastfeeding: a cross-sectional study among 401 Norwegian women.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Breast Feeding; Cross-Sectio | 2016 |
Metoclopramide and diphenhydramine in the treatment of hyperemesis gravidarum: effectiveness and predictors of rehospitalisation.
Topics: Adolescent; Adult; Antiemetics; Cohort Studies; Diphenhydramine; Drug Therapy, Combination; Female; | 2009 |
The safety of metoclopramide use in the first trimester of pregnancy.
Topics: Abnormalities, Drug-Induced; Antiemetics; Cohort Studies; Female; Fetus; Humans; Infant, Low Birth W | 2009 |
Wernicke encephalopathy complicating hyperemesis gravidarum: a case report.
Topics: Adult; Drug Therapy, Combination; Female; Humans; Hyperemesis Gravidarum; Metoclopramide; Niacinamid | 2010 |
Pediatric emergency medicine: legal briefs.
Topics: Accidental Falls; Adolescent; Adult; Antiemetics; Apnea; Bacteremia; Baseball; Brain Injuries; Cardi | 2010 |
Treatment of severe nausea and vomiting of pregnancy with subcutaneous medications.
Topics: Adolescent; Adult; Antiemetics; Female; Home Infusion Therapy; Humans; Infusions, Subcutaneous; Meto | 2011 |
Impact of data by Fujii and colleagues on the meta-analysis of metoclopramide for antiemetic prophylaxis in women undergoing Caesarean delivery under neuraxial anaesthesia.
Topics: Anesthesia, Obstetrical; Anesthesia, Spinal; Antiemetics; Cesarean Section; Female; Humans; Intraope | 2012 |
A survey of prescribing for the management of nausea and vomiting in pregnancy in Australasia.
Topics: Antiemetics; Australia; Dopamine Antagonists; Female; Histamine Antagonists; Humans; Hyperemesis Gra | 2013 |
Metoclopramide for nausea and vomiting of pregnancy: a prospective multicenter international study.
Topics: Adolescent; Adult; Antiemetics; Brazil; Canada; Case-Control Studies; Congenital Abnormalities; Dopa | 2002 |
Pressor responsiveness to intravenous quinpirole is blunted in malnourished, conscious rats: central vs. peripheral and spinal mechanisms.
Topics: Animals; Blood Pressure; Diet; Dopamine Agonists; Dopamine Antagonists; Drug Interactions; Female; H | 2004 |
Maternal medication causing drug dystonia in a newborn: placental transfer of drugs.
Topics: Cesarean Section; Dystonia; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Injections, | 2004 |
Measuring outpatient outcomes of emesis and nausea management in pregnant women.
Topics: Adult; Ambulatory Care; Antiemetics; Cost Control; Female; Humans; Metoclopramide; Morning Sickness; | 2004 |
Acid aspiration prophylaxis and caesarean delivery: time for another close look.
Topics: Anesthesia; Antacids; Cesarean Section; Female; Humans; Metoclopramide; Pneumonia, Aspiration; Pregn | 2005 |
Unsteady, unfocused, and unable to hear.
Topics: Adolescent; Cognition Disorders; Combined Modality Therapy; Female; Fluid Therapy; Gait Disorders, N | 2005 |
Metoclopramide-induced hyperprolactinaemia caused marked decline in pinopodes and pregnancy rates in mice.
Topics: Animals; Disease Models, Animal; Endometrium; Female; Hyperprolactinemia; Metoclopramide; Mice; Preg | 2006 |
Gastric emptying in labor.
Topics: Analgesics, Opioid; Female; Gastric Emptying; Humans; Labor, Obstetric; Metoclopramide; Pregnancy | 1980 |
Placental transfer and hormonal effects of metoclopramide.
Topics: Anesthesia, Obstetrical; Cesarean Section; Estradiol; Female; Follicle Stimulating Hormone; Humans; | 1983 |
[Study on the hypothalamic dopaminergic activity in different stages of pregnancy and non-pregnancy].
Topics: Abortion, Spontaneous; Bromocriptine; Female; Humans; Hypothalamus; Metoclopramide; Pregnancy; Pregn | 1984 |
The prolactin-releasing mechanism of the hypothalamo-pituitary axis in pregnancy.
Topics: Adult; Bromocriptine; Female; Humans; Hypothalamo-Hypophyseal System; Metoclopramide; Pituitary Glan | 1984 |
Does metoclopramide decrease the volume of gastric contents in patients undergoing cesarean section?
Topics: Adult; Anesthesia; Cesarean Section; Female; Gastric Acidity Determination; Gastrointestinal Content | 1984 |
Metoclopramide stimulation of prolactin secretion in women during puerperal lactation.
Topics: Adult; Female; Humans; Lactation; Metoclopramide; Postpartum Period; Pregnancy; Prolactin; Stimulati | 1984 |
[Diagnostic value of the prolactin stimulation test in infertile women with galactorrhea].
Topics: Female; Galactorrhea; Humans; Infertility, Female; Lactation Disorders; Metoclopramide; Pregnancy; P | 1984 |
Failure to thrive in the contented breast-fed baby.
Topics: Body Height; Body Weight; Breast Feeding; Chlorpromazine; Failure to Thrive; Female; Humans; Infant; | 1984 |
Acupuncture therapy does not change metoclopramide-induced prolactin secretion in normoprolactinaemic galactorrhea syndrome.
Topics: Acupuncture Therapy; Adult; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Pregn | 1984 |
Compensatory adrenal growth and conditioned avoidance response in relation to oestrous cycle and metoclopramide induced constant dioestrus.
Topics: Adrenal Glands; Animals; Avoidance Learning; Conditioning, Psychological; Estrus; Female; Metoclopra | 1984 |
Electron-capture determination of metoclopramide in biological fluids using fused silica capillary columns. Application to placental transport studies in sheep and humans.
Topics: Adult; Animals; Animals, Newborn; Chromatography, Gas; Female; Fetal Blood; Fetus; Half-Life; Humans | 1983 |
Metoclopramide challenge: a measure of human lactotroph activity.
Topics: Adult; Breast Feeding; Diagnosis, Differential; Female; Humans; Lactation; Menopause; Menstruation; | 1983 |
Failure of metoclopramide to release GH in pregnant women.
Topics: Dopamine; Female; Growth Hormone; Humans; Metoclopramide; Pregnancy | 1983 |
Metoclopramide and breast feeding: transfer into milk and the newborn.
Topics: Female; Fetal Blood; Humans; Infant, Newborn; Kinetics; Maternal-Fetal Exchange; Metoclopramide; Mil | 1983 |
[Galactorrhea induced by metoclopramid].
Topics: Adult; Bromocriptine; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Pregnancy; | 1983 |
Metoclopramide in lactational failure.
Topics: Adult; Drug Evaluation; Female; Humans; Lactation Disorders; Metoclopramide; Pregnancy | 1983 |
[Serum prolactin level in basal conditions and after metoclopramide stimulation in women with galactorrhea and in patients with pituitary tumors].
Topics: Adult; Female; Galactorrhea; Humans; Lactation Disorders; Male; Metoclopramide; Pituitary Neoplasms; | 1983 |
Antiemetic efficacy of droperidol and metoclopramide.
Topics: Abortion, Therapeutic; Adolescent; Adult; Anesthesia, General; Antiemetics; Droperidol; Female; Huma | 1984 |
[Metoclopramide in the complex treatment of chronic cholecystitis in pregnant women].
Topics: Adolescent; Adult; Cholecystitis; Chronic Disease; Female; Humans; Metoclopramide; Pregnancy; Pregna | 1984 |
Persistent defect in regulation of prolactin secretion after successful pituitary tumor removal in women with the galactorrhea-amenorrhea syndrome.
Topics: Amenorrhea; Chlorpromazine; Female; Galactorrhea; Humans; Insulin; Lactation Disorders; Metocloprami | 1980 |
[Effects of citicholine on pituitary gland function in normal subjects and in cases of idiopathic galactorrhea].
Topics: Adolescent; Adult; Choline; Cimetidine; Cytidine Diphosphate Choline; Female; Galactorrhea; Growth H | 1980 |
Metoclopramide increases prolactin release and milk secretion in puerperium without stimulating the secretion of thyrotropin and thyroid hormones.
Topics: Adult; Female; Humans; Lactation; Lactation Disorders; Metoclopramide; Milk, Human; Postpartum Perio | 1981 |
Galactorrhea-amenorrhea syndrome: follow-up of forty-five patients after pituitary tumor removal.
Topics: Adenoma; Adult; Amenorrhea; Chlorpromazine; Female; Follow-Up Studies; Galactorrhea; Humans; Lactati | 1981 |
Serum prolactin during pregnancy induced by pituitary gonadotrophins in a patient with post partum hypopituitarism (Sheehan syndrome).
Topics: Adult; Female; Fetal Blood; Gonadotropins, Pituitary; Humans; Hypopituitarism; Infertility, Female; | 1981 |
The relationship between metoclopramide and milk secretion in puerperium.
Topics: Adult; Female; Humans; Lactation; Metoclopramide; Postpartum Period; Pregnancy; Prolactin; Thyrotrop | 1981 |
[Lack of diagnostic value of pharmacodynamic tests in the differential diagnosis of hyperprolactinemia (author's transl)].
Topics: Adolescent; Adult; Diagnosis, Differential; Female; Humans; Metoclopramide; Pregnancy; Prolactin; Th | 1981 |
Failure of metoclopramide to affect thyrotropin concentration in the term human fetus.
Topics: Female; Fetal Blood; Fetus; Humans; Labor, Obstetric; Maternal-Fetal Exchange; Metoclopramide; Pregn | 1983 |
Effect of metoclopramide on maternal and fetal hyperprolactinemia.
Topics: Female; Fetal Blood; Humans; Labor, Obstetric; Maternal-Fetal Exchange; Metoclopramide; Pregnancy; P | 1983 |
Galactorrhoea.
Topics: Adult; Female; Galactorrhea; Humans; Hypothalamo-Hypophyseal System; Lactation Disorders; Metoclopra | 1982 |
[Comparative statistical study of two antiemetics, metoclopramide and metopimazine, effects on the oestrus cycle in the female rat (author's transl)].
Topics: Animals; Antiemetics; Diestrus; Estrus; Female; Isonipecotic Acids; Metoclopramide; Phenothiazines; | 1980 |
Effects of metoclopramide and bromocriptine on prolactin secretion in the pregnant ewe.
Topics: Animals; Bromocriptine; Female; Metoclopramide; Pituitary Gland; Pregnancy; Pregnancy, Animal; Prola | 1982 |
Gastric volume in early pregnancy: effect of metoclopramide.
Topics: Abortion, Therapeutic; Double-Blind Method; Female; Gastric Acidity Determination; Humans; Metoclopr | 1982 |
Reduced dopaminergic inhibition of thyrotrophin release in states of physiological hyperprolactinaemia.
Topics: Adult; Female; Humans; Hypothalamus; Metoclopramide; Postpartum Period; Pregnancy; Prolactin; Thyroi | 1982 |
Bioactivity of prolactin in a woman with an excess of large molecular size prolactin, persistent hyperprolactinemia and spontaneous conception.
Topics: Abortion, Spontaneous; Adult; Anovulation; Biological Assay; Female; Humans; Metoclopramide; Molecul | 1982 |
Effect of metoclopramide on maternal and fetal prolactin secretion during labor.
Topics: Administration, Oral; Female; Fetal Blood; Humans; Infant, Newborn; Injections, Intravenous; Labor, | 1982 |
[The effects of metoclopramide on maternal, umbilical and amniotic fluid prolactin at delivery].
Topics: Amniotic Fluid; Delivery, Obstetric; Female; Fetal Blood; Humans; Labor, Obstetric; Metoclopramide; | 1982 |
Hyperprolactinemia and galactorrhea: spontaneous versus iatrogenic hypothyroidism.
Topics: Adolescent; Adult; Aged; Female; Galactorrhea; Humans; Hypothyroidism; Iatrogenic Disease; Lactation | 1981 |
[Menstrual migraine].
Topics: Adult; Bromocriptine; Chiari-Frommel Syndrome; Estrogens; Female; Galactorrhea; Gout; Humans; Menstr | 1982 |
Galactorrhoea, hyperprolactinaemia, and pituitary adenoma presenting during metoclopramide therapy.
Topics: Adenoma; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Middle Aged; Pituitary N | 1982 |
Prl, TSH, GH and LH responses to metoclopramide and breast-feeding in normal and hyperprolactinaemic women.
Topics: Adenoma; Adult; Breast Feeding; Female; Growth Hormone; Humans; Lactation; Luteinizing Hormone; Meto | 1982 |
[Experience with metoclopramide therapy in early pregnancy toxicosis].
Topics: Adult; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Metoclopramide; Pre-Eclampsia; Pr | 1981 |
The acute effect of metoclopramide on plasma prolactin during pregnancy.
Topics: Female; Humans; Metoclopramide; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; | 1981 |
Central nervous system-mediated stimulation of prolactin secretion by cimetidine, a histamine H2-receptor antagonist: impaired responsiveness in patients with prolactin-secreting tumors and idiopathic hyperprolactinemia.
Topics: Adenoma; Adolescent; Adult; Animals; Carbidopa; Cimetidine; Female; Guanidines; Humans; Levodopa; Ma | 1980 |
Behavioural retardation in the neuropathology of mental retardation.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Dihydroxyphenylalanine; Dopamine Agents; Female; Ha | 1993 |
Effects of ovarian surgery on the dopaminergic and opioidergic control of gonadotropin and prolactin secretion in women with polycystic ovarian disease.
Topics: Adult; Dopamine; Endorphins; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Humans; | 1993 |
Metoclopramide exaggerates stress-induced tachycardia in pregnant sheep.
Topics: Animals; Antiemetics; Blood Pressure; Carbon Dioxide; Dopamine Antagonists; Female; Fetal Distress; | 1996 |
Use of dipyrone during pregnancy and risk of Wilms' tumor. Brazilian Wilms' Tumor Study Group.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Dipyrone; Female; Humans; Income; Kidney Neopl | 1996 |
Differences in the metoclopramide-induced prolactin release related to age at first full-term pregnancy or nulliparity.
Topics: Age Factors; Dopamine Antagonists; Female; Humans; Metoclopramide; Parity; Pregnancy; Prolactin | 1997 |
Acute intermittent porphyria precipitated by hyperemesis and metoclopramide treatment in pregnancy.
Topics: Adult; Antiemetics; Female; Glucose Solution, Hypertonic; Hemin; Humans; Hyperemesis Gravidarum; Met | 1997 |
Pheochromocytoma in pregnancy manifesting hypertensive crisis induced by metoclopramide.
Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Antiemetics; Female; Humans; Hypertens | 1997 |
Birth outcome following maternal use of metoclopramide. The Euromap study group.
Topics: Adolescent; Adult; Antiemetics; Databases, Factual; Female; Humans; Metoclopramide; Pregnancy; Pregn | 2000 |
Fetal effects of metoclopramide therapy for nausea and vomiting of pregnancy.
Topics: Abortion, Spontaneous; Antiemetics; Case-Control Studies; Congenital Abnormalities; Female; Fetus; H | 2000 |
Home subcutaneous metoclopramide therapy for hyperemesis gravidarum.
Topics: Adult; Antiemetics; Female; Home Care Services; Humans; Hyperemesis Gravidarum; Infusion Pumps; Inje | 2000 |
Maternal prolactin secretion during labor. The role of dopamine.
Topics: Administration, Oral; Adult; Bromocriptine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Femal | 2001 |
[Acute dystonia caused by metoclopramide (Afipran) therapy].
Topics: Acute Disease; Adult; Antiemetics; Dyskinesia, Drug-Induced; Female; Humans; Male; Metoclopramide; P | 2001 |
Diseases of the alimentary system; Nausea and vomiting.
Topics: Antiemetics; Female; Histamine H1 Antagonists; Humans; Metoclopramide; Motion Sickness; Nausea; Phen | 1976 |
Anti-nauseant drugs.
Topics: Antiemetics; Antipsychotic Agents; Female; Gastrointestinal Diseases; Histamine H1 Antagonists; Huma | 1979 |
Narcotic analgesics and delayed gastric emptying during labour.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Anesthesia, Obstetrical; | 1975 |
Letter: Narcotic analgesics and delayed gastric emptying during labour.
Topics: Anesthesia, Obstetrical; Diazepam; Female; Humans; Labor, Obstetric; Metoclopramide; Pregnancy; Stom | 1975 |
Antacids and cricoid pressure in prevention of fatal aspiration syndrome.
Topics: Anesthesia, Obstetrical; Female; Gastric Emptying; Humans; Metoclopramide; Middle Aged; Pneumonia, A | 1979 |
Dynamic evaluation of prolactin secretion in patients with oligospermia: effects of treatment with metergoline.
Topics: Adult; Ergolines; Female; Humans; Levodopa; Male; Metergoline; Metoclopramide; Oligospermia; Pregnan | 1979 |
The effect of metoclopramide, TRH and L-dopa on prolactin secretion in pituitary adenoma and in "functional" galactorrhoea syndrome.
Topics: Acromegaly; Adenoma; Adult; Amenorrhea; Female; Galactorrhea; Humans; Lactation Disorders; Levodopa; | 1979 |
Prolactin-secreting pituitary adenomas: prolactin dynamics before and after transsphenoidal surgery.
Topics: Adenoma; Adolescent; Adult; Bromocriptine; Female; Humans; Hypothalamus; Metergoline; Metoclopramide | 1979 |
Clinical and endocrinological analyses of patients with galactorrhea and menstrual disorders due to sulpiride or metoclopramide.
Topics: Adult; Female; Follicle Stimulating Hormone; Galactorrhea; Gastrointestinal Diseases; Gonadotropin-R | 1978 |
Serum prolactin response to thyrotropin-releasing hormone and metoclopramide in patients with prolactin-secreting tumors before and after transsphenoidal surgery.
Topics: Adenoma; Adolescent; Adult; Female; Humans; Lactation; Metoclopramide; Pituitary Neoplasms; Pregnanc | 1978 |
Pituitary autonomy in hyperprolactinemic secondary amenorrhea: results of hypothalamic-pituitary testing.
Topics: Adult; Amenorrhea; Bromocriptine; Clomiphene; Female; Galactorrhea; Humans; Hypothalamo-Hypophyseal | 1977 |
Metoclopramide and the gastro-oesophageal sphincter.
Topics: Anesthesia, Obstetrical; Esophagogastric Junction; Female; Humans; Metoclopramide; Preanesthetic Med | 1979 |
Relactation: an overview.
Topics: Breast Feeding; Chlorpromazine; Developing Countries; Female; Humans; Lactation; Metoclopramide; Pre | 1977 |
[Blood prolactin study in four cases of galactorrhea (author's transl)].
Topics: Administration, Oral; Adult; Female; Galactorrhea; Humans; Lactation Disorders; Male; Metoclopramide | 1977 |
Clinical use of metoclopramide test in the diagnosis of women with hyperprolactinemia.
Topics: Adult; Amenorrhea; Female; Galactorrhea; Humans; Male; Metoclopramide; Pituitary Neoplasms; Pregnanc | 1979 |
Effect of chronic metoclopramide therapy on serum pituitary hormone concentrations.
Topics: Adult; Aged; Erectile Dysfunction; Female; Galactorrhea; Humans; Male; Metoclopramide; Middle Aged; | 1979 |
[Hyperprolactinemia and galactorrhea induced by metoclopramide (Primperan)].
Topics: Adolescent; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Pregnancy; Prolactin | 1979 |
[Therapeutic experience in the treatment of some gastrointestinal disorders during pregnancy].
Topics: Adult; Antacids; Drug Combinations; Drug Evaluation; Female; Gastrointestinal Diseases; Humans; Meto | 1977 |
Relactation with reference to application in developing countries.
Topics: Breast Feeding; Chlorpromazine; Developing Countries; Estrogens; Female; Humans; India; Lactation; M | 1978 |
The synaptic significance of metoclopramide induced dyskinetic-dystonic head and neck movements in pregnancy.
Topics: Adolescent; Adult; Dyskinesia, Drug-Induced; Female; Head; Humans; Hyperemesis Gravidarum; Metoclopr | 1978 |
The effect of metoclopramide on the lower oesophageal sphincter in late pregnancy.
Topics: Adolescent; Adult; Esophagogastric Junction; Female; Gastroesophageal Reflux; Heartburn; Humans; Met | 1978 |
Anaesthesia for caesarean section.
Topics: Anesthesia, Intravenous; Anesthesia, Obstetrical; Atropine; Cesarean Section; Female; Humans; Metocl | 1978 |
Gastro-oesophageal reflux in pregnancy: a review article.
Topics: Esophagogastric Junction; Female; Gastrins; Gastroesophageal Reflux; Hernia, Hiatal; Humans; Metoclo | 1978 |
Gastric emptying in labour: some recent findings and their clinical significance.
Topics: Anesthesia, Obstetrical; Digestion; Female; Gastric Emptying; Heroin; Humans; Labor, Obstetric; Mepe | 1978 |
Hyperprolactinaemia: its physiology and investigation.
Topics: Adenoma, Chromophobe; Amenorrhea; Bromocriptine; Female; Galactorrhea; Humans; Male; Metabolic Disea | 1976 |
Metoclopramide hydrochloride and galactorrhea.
Topics: Adult; Female; Galactorrhea; Humans; Lactation Disorders; Metoclopramide; Pregnancy | 1976 |
Breast feeding in Brazil.
Topics: Bibliographies as Topic; Brazil; Breast Feeding; Female; Humans; Lactation; Metoclopramide; Pregnanc | 1975 |
Proceedings: Narcotic analgesics and delayed gastric emptying in labour.
Topics: Anesthesia, Obstetrical; Female; Gastrointestinal Motility; Heroin; Humans; Labor, Obstetric; Meperi | 1975 |
Letter: Metoclopramide and breast-feeding.
Topics: Animals; Breast Feeding; Female; Humans; Lactation; Metoclopramide; Milk; Pregnancy | 1975 |
Gastro-intestinal absorption and transplacental transfer of amoxycillin during labour and the influence of metoclopramide.
Topics: Amniotic Fluid; Amoxicillin; Ampicillin; Female; Gastric Mucosa; Humans; Intestinal Absorption; Labo | 1975 |
Proceedings: Visualization of retino-hypothalamic projections in the rat.
Topics: Animals; Dopamine; Female; Haloperidol; Lactation; Metoclopramide; Milk Ejection; Pregnancy; Rats | 1975 |
Immunoradiometric analysis of circulating human glycosylated and nonglycosylated prolactin forms: spontaneous and stimulated secretions.
Topics: Adult; Aged; Antibodies, Monoclonal; Circadian Rhythm; Electrophoresis, Polyacrylamide Gel; Female; | 1992 |
Thyrotropin-releasing hormone (TRH) and metoclopramide testing in infertile women.
Topics: Dehydroepiandrosterone; Dopamine Agents; Estradiol; Female; Fertilization; Follicle Stimulating Horm | 1991 |
[An experimental study of inhibition on lactation in fluorosis rats].
Topics: Animals; Female; Fluoride Poisoning; Lactation; Metoclopramide; Pituitary Gland; Pregnancy; Prolacti | 1991 |
[Studies on metoclopramide (MCP) loading test during pregnancy and puerperium for the evaluation of lactating capacity].
Topics: Female; Humans; Lactation; Metoclopramide; Postpartum Period; Pregnancy; Pregnancy Trimester, Third; | 1991 |
Fetal and maternal placental and nonplacental clearances of metoclopramide in chronically instrumented pregnant sheep.
Topics: Animals; Blood Gas Monitoring, Transcutaneous; Catheterization; Female; Fetus; Infusions, Intravenou | 1990 |
Avoidance behavior, prolactin, HVA and DOPAC in offspring of bromopride-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Avoidance Learning; Corpus Striatum; Dopamine; Female; Homo | 1990 |
Hypothalamic amenorrhea: clinical perspectives, pathophysiology, and management.
Topics: Amenorrhea; Anovulation; Dopamine; Endorphins; Estradiol; Female; Follicle Stimulating Hormone; Gona | 1990 |
The metoclopramid-provocation test for prediction of transient hyperprolactinemia during cycle stimulation.
Topics: Embryo Transfer; Estradiol; Female; Fertilization in Vitro; Humans; Hyperprolactinemia; Menstrual Cy | 1990 |
Metoclopramide--a safe anti-emetic?
Topics: Anesthesia, Obstetrical; Cesarean Section; Female; Humans; Metoclopramide; Preanesthetic Medication; | 1990 |
Role of prolactin in lactation-induced changes in brown adipose tissue.
Topics: Adipose Tissue, Brown; Animals; Body Temperature Regulation; Bromocriptine; Female; Lactation; Metoc | 1990 |
Clinical, haematological and biochemical findings and the results of treatment in cattle with acute functional pyloric stenosis.
Topics: Acute Disease; Alkalosis; Animals; Bile Acids and Salts; Cattle; Cattle Diseases; Chlorides; Female; | 1990 |
Anesthetic management of a pregnant patient with the hyperimmunoglobulin E (Job's) syndrome.
Topics: Abscess; Adult; Anesthesia, Epidural; Drainage; Female; Hip Joint; Humans; Isoflurane; Job Syndrome; | 1990 |
Effects of altered photoperiod or maternal melatonin administration on plasma prolactin concentrations in fetal lambs.
Topics: Animals; Female; Fetus; Light; Maternal-Fetal Exchange; Melatonin; Metoclopramide; Pregnancy; Pregna | 1989 |
[Hypogalactia: therapeutic possibilities].
Topics: Administration, Oral; Adult; Domperidone; Female; Humans; Lactation; Lactation Disorders; Metoclopra | 1989 |
BRL 24924: a potent agonist at a non-classical 5-HT receptor positively coupled with adenylate cyclase in colliculi neurons.
Topics: Adenylyl Cyclases; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Hetero | 1989 |
A simple rapid method for prolactin assay by reversed passive hemagglutination: evaluation of its clinical application.
Topics: Amenorrhea; Antibodies, Monoclonal; Bromocriptine; Female; Hemagglutination Tests; Humans; Metoclopr | 1989 |
[Dopaminergic control of aldosterone and prolactin secretion during normal pregnancy and toxemia of pregnancy].
Topics: Aldosterone; Chorionic Gonadotropin; Dopamine; Dopamine Antagonists; Estradiol; Female; Fetal Blood; | 1989 |
[Dystonic-dyskinetic syndrome following metoclopramide (Cerucal) administration to promote lactation].
Topics: Administration, Oral; Adult; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Dystonia; F | 1989 |
Perinatal bromopride treatment: effects on sexual behavior of male and female rats.
Topics: Animals; Animals, Newborn; Copulation; Dose-Response Relationship, Drug; Estradiol; Female; Male; Me | 1989 |
Perinatal bromopride treatment: effects on motor activity and stereotyped behavior of offspring.
Topics: Animals; Apomorphine; Dose-Response Relationship, Drug; Female; Lactation; Male; Metoclopramide; Mot | 1989 |
Treatment of common minor ailments.
Topics: Acetaminophen; Antacids; Antiemetics; Aspirin; Dyspepsia; Female; Heartburn; Histamine H1 Antagonist | 1986 |
Acute intermittent porphyria in pregnancy.
Topics: Acute Disease; Adult; Diagnosis, Differential; Female; Fluid Therapy; Genes, Dominant; Humans; Hyper | 1989 |
[Study of the correlation between gonadotropin- and prolactin-releasing systems in women in the luteal phase and early pregnancy].
Topics: Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Gonadotropins; Huma | 1986 |
Evidence that opioid peptides and dopamine participate in the suckling-induced release of prolactin in the ewe.
Topics: Animals; Apomorphine; Dopamine; Endorphins; Female; Lactation; Metoclopramide; Naloxone; Pituitary G | 1986 |
Isolated prolactin deficiency in a woman with puerperal alactogenesis.
Topics: Adult; Biological Assay; Female; Gonadotropin-Releasing Hormone; Humans; Lactation Disorders; Menstr | 1987 |
[Study on the neuroendocrinological control of prolactin release in early puerperium].
Topics: Bromocriptine; Cimetidine; Dopamine; Endorphins; Female; Histamine; Humans; Hypothalamo-Hypophyseal | 1987 |
[Promoting lactation with the aid of drugs].
Topics: Chlorpromazine; Cimetidine; Domperidone; Female; Humans; Lactation; Medroxyprogesterone; Metoclopram | 1987 |
Prolactin levels in male and female rats perinatally treated with bromopride.
Topics: Animals; Behavior, Animal; Dopamine Antagonists; Female; Male; Metoclopramide; Pregnancy; Prolactin; | 1988 |
Prolactin stimulation tests: different response patterns after bromocriptine, lisuride, and metergoline treatment of puerperal women.
Topics: Adult; Bromocriptine; Ergolines; Female; Humans; Lisuride; Metergoline; Metoclopramide; Postpartum P | 1988 |
Supraventricular tachycardia associated with postpartum metoclopramide administration.
Topics: Adult; Female; Humans; Metoclopramide; Postpartum Period; Pregnancy; Sterilization, Tubal; Tachycard | 1988 |
Silent regurgitation in day case gynaecological patients.
Topics: Adult; Ambulatory Surgical Procedures; Female; Gastroesophageal Reflux; Genital Diseases, Female; Hu | 1988 |
Metoclopramide pharmacokinetics in pregnant and nonpregnant sheep.
Topics: Animals; Blood Gas Analysis; Female; Fetus; Gestational Age; Hydrogen-Ion Concentration; Injections, | 1988 |
Treatment of pseudopregnancy with bromocriptin, an ergot alkaloid.
Topics: Animals; Bromocriptine; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Lactation; Metoclopra | 1986 |
Administration of metoclopramide for prevention of nausea and vomiting during epidural anesthesia for elective cesarean section.
Topics: Anesthesia, Epidural; Cesarean Section; Female; Fentanyl; Gestational Age; Humans; Metoclopramide; M | 1987 |
Drug accumulation in lung fluid of the fetal lamb after maternal or fetal administration.
Topics: Animals; Body Fluids; Diphenhydramine; Female; Lung; Maternal-Fetal Exchange; Metoclopramide; Pregna | 1987 |
[Evaluation of the dopaminergic neuroendocrine control of prolactin release during labor in humans].
Topics: Adult; Dopamine; Dopamine Antagonists; Female; Growth Hormone; Humans; Hydrocortisone; Labor, Obstet | 1986 |
Induced hypotension for clipping of a cerebral aneurysm during pregnancy: a case report and brief review.
Topics: Adult; Anesthesia, Inhalation; Blood Pressure; Cimetidine; Female; Fetal Monitoring; Humans; Hypoten | 1986 |
Prolactin-releasing system in maternal, fetal, and amniotic compartments during labor.
Topics: Adult; Amniotic Fluid; Female; Fetal Blood; Humans; Hypothalamo-Hypophyseal System; Labor, Obstetric | 1986 |
Metoclopramide effect on faltering milk production by mothers of premature infants.
Topics: Adult; Breast Feeding; Drug Evaluation; Female; Humans; Infant, Newborn; Infant, Premature; Lactatio | 1986 |
[Relation between corpus luteum function and serum prolactin concentration early in pregnancy].
Topics: Corpus Luteum; Estradiol; Female; Humans; Metoclopramide; Pregnancy; Pregnancy Trimester, First; Pro | 1986 |
Prolactin secretion during pregnancy and puerperium: response to metoclopramide and interactions with placental hormones.
Topics: Animals; Breast Feeding; Estradiol; Estriol; Female; Humans; Lactation; Metoclopramide; Milk; Placen | 1985 |
Long-term bromocriptine therapy may restore the inhibitory control of prolactin release in some patients with pathological hyperprolactinemia.
Topics: Adenoma; Adolescent; Adult; Bromocriptine; Female; Humans; Male; Metoclopramide; Middle Aged; Pituit | 1985 |
[Drug control of milk excretion].
Topics: Breast Feeding; Female; Humans; Lactation; Metoclopramide; Pregnancy; Prolactin; Sulpiride; Thyrotro | 1985 |
Metoclopramide as a lactogogue.
Topics: Adult; Body Weight; Breast Feeding; Drug Evaluation; Female; Humans; Lactation Disorders; Metoclopra | 1985 |
[Effect of dopaminergic agents on the endocrine profile in labor and early puerperium].
Topics: Bromocriptine; Estradiol; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Labor, Obs | 1985 |
[Primperan during pregnancy].
Topics: Female; Heartburn; Humans; Metoclopramide; Pneumonia, Aspiration; Pregnancy; Pregnancy Complications | 1985 |
Evaluation of dopaminergic tone in hyperprolactinemia. III. Thyroid-stimulating hormone response to metoclopramide in differential diagnosis and postoperative follow-up of prolactinoma patients.
Topics: Adenoma; Adolescent; Adult; Diagnosis, Differential; Empty Sella Syndrome; Female; Humans; Hyperprol | 1985 |
[Oesophageal stenosis in hereditary epidermolysis bullosa (author's transl)].
Topics: Child; Child, Preschool; Deglutition Disorders; Epidermolysis Bullosa; Esophageal Stenosis; Esophago | 1974 |