metoclopramide has been researched along with Polycystic Ovarian Syndrome in 16 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to investigate the DA activity in polycystic ovary syndrome (PCOS) we studied the response of LH, FSH and PRL to a dopamine receptor antagonist metoclopramide (MCP-10 mg iv) in 12 PCO subjects (7 with normal and 5 with elevated levels of prolactin)." | 7.67 | Metoclopramide effect on serum prolactin LH and FSH in patients with polycystic ovary syndrome. ( Perić, LA; Prelević, GM; Würzburger, MI, 1988) |
| "In order to investigate the DA activity in polycystic ovary syndrome (PCOS) we studied the response of LH, FSH and PRL to a dopamine receptor antagonist metoclopramide (MCP-10 mg iv) in 12 PCO subjects (7 with normal and 5 with elevated levels of prolactin)." | 3.67 | Metoclopramide effect on serum prolactin LH and FSH in patients with polycystic ovary syndrome. ( Perić, LA; Prelević, GM; Würzburger, MI, 1988) |
| "To further investigate prolactin (PRL) secretion in polycystic ovary syndrome (PCO), the authors evaluated immunoreactive (immuno) and bioactive (bio) PRL levels in the basal state and in response to provocative testing with intravenous dopamine (DA), metoclopramide (MCP), and gonadotropin-releasing hormone (GnRH), before and after disulfiram." | 3.67 | Secretory dynamics of bioactive and immunoreactive prolactin in polycystic ovary syndrome. ( Anderson, RE; Barnes, RB; Ben-Rafael, Z; Flickinger, GL; Lobo, RA; Meloni, F; Rosen, GF, 1988) |
| "Group C- 70 patients with FAI<5 and irregular menstruation, group D - 65 patients with FAI<5 and regular menstruation." | 1.51 | Basal and metoclopramide induced prolactin secretion in lean PCOS women. ( Dabrowski, FA; Doroszewska, K; Gałuszka-Bednarczyk, A; Guzik, J; Janeczko, M; Kiałka, M; Marianowski, P; Milewicz, T; Mrozinska, S; Przywara-Sikora, A, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (62.50) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Rodier, C | 1 |
| Courbière, B | 1 |
| Fernandes, S | 1 |
| Vermalle, M | 1 |
| Florence, B | 1 |
| Resseguier, N | 1 |
| Brue, T | 1 |
| Cuny, T | 1 |
| Mrozinska, S | 1 |
| Przywara-Sikora, A | 1 |
| Doroszewska, K | 1 |
| Gałuszka-Bednarczyk, A | 1 |
| Kiałka, M | 1 |
| Guzik, J | 1 |
| Janeczko, M | 1 |
| Marianowski, P | 1 |
| Dabrowski, FA | 1 |
| Milewicz, T | 1 |
| Noczyńska, A | 1 |
| Wasikowa, R | 1 |
| Cumming, DC | 1 |
| Reid, RL | 1 |
| Quigley, ME | 1 |
| Rebar, RW | 1 |
| Yen, SS | 1 |
| Baranowska, B | 1 |
| Jeske, W | 1 |
| Stopińska-Głuszak, U | 1 |
| Alger, M | 1 |
| Vazquez-Matute, L | 1 |
| Mason, M | 1 |
| Canales, ES | 1 |
| Zárate, A | 1 |
| Szilágyi, A | 1 |
| Hole, R | 1 |
| Keckstein, J | 1 |
| Rossmanith, WG | 1 |
| Vĕtr, M | 1 |
| Talas, M | 1 |
| Sobek, A | 1 |
| Charamza, J | 1 |
| Lissak, A | 1 |
| Dirnfeld, M | 1 |
| Sorokin, Y | 1 |
| Kahana, L | 1 |
| Abramovici, H | 1 |
| Koch, Y | 1 |
| Ferriani, RA | 1 |
| Silva de Sá, MF | 1 |
| Moura, MD | 1 |
| Moreira, AC | 1 |
| Gomes, UA | 1 |
| Nappi, C | 1 |
| Petraglia, F | 1 |
| Di Carlo, C | 1 |
| De Rosa, R | 1 |
| Zaccardo, A | 1 |
| Genazzani, AR | 1 |
| Montemagno, U | 1 |
| Prelević, GM | 1 |
| Würzburger, MI | 1 |
| Perić, LA | 1 |
| Minakami, H | 2 |
| Abe, N | 1 |
| Oka, N | 1 |
| Kimura, K | 2 |
| Tamura, T | 1 |
| Tamada, T | 2 |
| Anderson, RE | 1 |
| Ben-Rafael, Z | 1 |
| Flickinger, GL | 1 |
| Meloni, F | 1 |
| Barnes, RB | 2 |
| Rosen, GF | 1 |
| Lobo, RA | 2 |
| Mileikowsky, GN | 1 |
| Cha, KY | 1 |
| Spencer, CA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Metoclopramide in Poor Ovarian Response IVF Patients: a Randomised, Double-blind, Placebo-controlled Trial[NCT03560583] | 60 participants (Anticipated) | Interventional | 2021-07-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for metoclopramide and Polycystic Ovarian Syndrome
| Article | Year |
|---|---|
[Serum prolactin concentration after metoclopramide stimulation in patients with polycystic ovary syndrome].
Topics: Adolescent; Adult; Female; Humans; Metoclopramide; Pituitary Function Tests; Pituitary Gland, Anteri | 1983 |
2 trials available for metoclopramide and Polycystic Ovarian Syndrome
| Article | Year |
|---|---|
The effect of metoclopramide on ovarian responsiveness to gonadotropin administration in patients with severe polycystic ovarian syndrome.
Topics: Drug Therapy, Combination; Estradiol; Female; Gonadotropins; Humans; Menstrual Cycle; Metoclopramide | 1990 |
Dopamine might not be involved in the pathogenesis of polycystic ovary syndrome.
Topics: Adolescent; Adult; Androgens; Bromocriptine; Dopamine; Estradiol; Female; Follicle Stimulating Hormo | 1989 |
13 other studies available for metoclopramide and Polycystic Ovarian Syndrome
| Article | Year |
|---|---|
Metoclopramide Test in Hyperprolactinemic Women With Polycystic Ovarian Syndrome: Old Wine Into New Bottles?
Topics: Female; Humans; Male; Metoclopramide; Pituitary Neoplasms; Polycystic Ovary Syndrome; Prolactinoma; | 2022 |
Basal and metoclopramide induced prolactin secretion in lean PCOS women.
Topics: Administration, Oral; Adult; Diagnostic Techniques, Endocrine; Female; Humans; Hyperprolactinemia; M | 2019 |
Hyperprolactinemia in children during the peripubertal period--personal observations.
Topics: Adolescent; Age Factors; Amenorrhea; Biomarkers; Female; Galactorrhea; Gynecomastia; Humans; Hyperpr | 2004 |
Evidence for decreased endogenous dopamine and opioid inhibitory influences on LH secretion in polycystic ovary syndrome.
Topics: beta-Endorphin; Depression, Chemical; Endorphins; Female; Humans; Hypothalamus; Luteinizing Hormone; | 1984 |
Polycystic ovarian disease associated with hyperprolactinemia and defective metoclopramide response.
Topics: Adult; Bromocriptine; Female; Humans; Hypothalamo-Hypophyseal System; Metoclopramide; Polycystic Ova | 1980 |
Effects of ovarian surgery on the dopaminergic and opioidergic control of gonadotropin and prolactin secretion in women with polycystic ovarian disease.
Topics: Adult; Dopamine; Endorphins; Female; Follicle Stimulating Hormone; Gonadotropins, Pituitary; Humans; | 1993 |
Metoclopramide test in women with PCO syndrome after ovarian wedge resection.
Topics: Adult; Female; Humans; Metoclopramide; Ovariectomy; Polycystic Ovary Syndrome; Prolactin | 1991 |
Impairment of dopaminergic and opioidergic activity in patients with polycystic ovarian disease is restored by treatment for the induction of ovulation.
Topics: Adult; Dopamine; Endorphins; Female; Humans; Luteinizing Hormone; Metoclopramide; Naloxone; Ovulatio | 1989 |
Metoclopramide effect on serum prolactin LH and FSH in patients with polycystic ovary syndrome.
Topics: Adolescent; Adult; Dopamine; Female; Follicle Stimulating Hormone; Humans; Injections, Intravenous; | 1988 |
Prolactin release in polycystic ovarian syndrome.
Topics: Adolescent; Adult; Androstenedione; Animals; Estrus; Female; Follicle Stimulating Hormone; Humans; L | 1988 |
[A longitudinal study on the prognosis of ovulatory disturbance in teenage patients with high LH and normal FSH serum levels].
Topics: Adolescent; Androstenedione; Dopamine Antagonists; Female; Follicle Stimulating Hormone; Humans; Jap | 1988 |
Secretory dynamics of bioactive and immunoreactive prolactin in polycystic ovary syndrome.
Topics: Adult; Disulfiram; Dopamine; Female; Humans; Metoclopramide; Pituitary Hormone-Releasing Hormones; P | 1988 |
Effects of dopamine and metoclopramide in polycystic ovary syndrome.
Topics: Adult; Dopamine; Female; Humans; Luteinizing Hormone; Metoclopramide; Polycystic Ovary Syndrome; Pro | 1986 |