metoclopramide has been researched along with Peptic Ulcer in 27 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors studied the effect of single intakes of metoclopramide on the acid and pepsin secretion in patients with chronic gastritis and duodenal ulcer." | 7.67 | [The effect of metoclopramide on the acid and pepsin secretion of patients with chronic gastritis and peptic ulcer]. ( Makara, VZ; Skliarov, EIa, 1989) |
| " A third drug, lactulose (useful in treating hepatic encephalopathy), will soon be available." | 4.75 | Some aspects of medical management of gastrointestinal disease. I. ( Badley, BW, 1975) |
| "The authors studied the effect of single intakes of metoclopramide on the acid and pepsin secretion in patients with chronic gastritis and duodenal ulcer." | 3.67 | [The effect of metoclopramide on the acid and pepsin secretion of patients with chronic gastritis and peptic ulcer]. ( Makara, VZ; Skliarov, EIa, 1989) |
| " Cimetidine, a histamine HI-receptor antagonist, is an effective suppressant of acid secretion and therefore promotes healing of duodenal ulcers." | 3.66 | Symposium on peptic ulcer disease. 1. Medical treatment of peptic ulcer. ( Jeejeebhoy, KN, 1978) |
| "Seventeen patients with acute, persistent postvagotomy atony after vagotomy with antrectomy or pyrloroplasty for peptic ulcer underwent a doubleblind study of the relief of postvagotomy atony by metoclopramide." | 3.66 | Relief of acute, persistent postvagotomy atony by metoclopramide. ( Horton, JW; McClelland, RN, 1978) |
| "Dyspepsia affects one in four Australians; of those who present in general practice, the majority will have functional or non-ulcer dyspepsia, with no structural explanation for their symptoms." | 2.39 | Modern management of dyspepsia. ( Talley, NJ, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (85.19) | 18.7374 |
| 1990's | 4 (14.81) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muraoka, T | 1 |
| Prusiński, A | 1 |
| Neumayr, A | 1 |
| Weiss, W | 1 |
| Tolva, D | 1 |
| Testaguzza, F | 2 |
| Conti, F | 1 |
| Pomelov, VS | 1 |
| Baramidze, GG | 1 |
| Talley, NJ | 1 |
| Witzel, L | 1 |
| Halter, F | 1 |
| Geller, LI | 1 |
| Petrenko, VF | 1 |
| Badley, BW | 1 |
| Lux, G | 2 |
| Jeejeebhoy, KN | 1 |
| Laudano, OM | 1 |
| Heinkelein, J | 1 |
| Shchedrunov, VV | 1 |
| Onikienko, BA | 1 |
| Nikolaev, NA | 1 |
| McClelland, RN | 1 |
| Horton, JW | 1 |
| Shearman, DJ | 1 |
| Kocián, J | 1 |
| Kociánová, J | 1 |
| Noll, AM | 1 |
| Pinsky, D | 1 |
| Arora, A | 1 |
| Nijhawan, S | 1 |
| Skliarov, EIa | 1 |
| Makara, VZ | 1 |
| Tsimmerman, IaS | 1 |
| Ivanova, VS | 1 |
| Modestova, EV | 1 |
| Rotenberg, GB | 1 |
| Lewis, JH | 1 |
| Weingold, AB | 1 |
| Lederer, PC | 1 |
| Fisher, AA | 1 |
| Borisov, IuIu | 1 |
| Stadler, H | 1 |
| Giebler, A | 1 |
| Tscheliessnigg, KH | 1 |
| Berger, A | 1 |
| Mischinger, HJ | 1 |
| Ottenjann, R | 1 |
4 reviews available for metoclopramide and Peptic Ulcer
| Article | Year |
|---|---|
Modern management of dyspepsia.
Topics: Adult; Aged; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Bismuth; Child; C | 1996 |
Some aspects of medical management of gastrointestinal disease. I.
Topics: Diarrhea; Disaccharides; Endoscopy; Esophagitis; Gastric Juice; Gastric Mucosa; Gastrointestinal Dis | 1975 |
[Current status of peptic ulcer therapy].
Topics: Antacids; Carbenoxolone; Cholestyramine Resin; Humans; Metoclopramide; Parasympatholytics; Peptic Ul | 1978 |
The use of gastrointestinal drugs during pregnancy and lactation.
Topics: Adrenal Cortex Hormones; Animals; Antidiarrheals; Antiemetics; Cathartics; Diuretics; Female; Gastro | 1985 |
5 trials available for metoclopramide and Peptic Ulcer
| Article | Year |
|---|---|
[Long-term therapy of gastrointestinal diseases with gastronerton].
Topics: Adult; Aged; Antiemetics; Drug Evaluation; Female; Gastrointestinal Diseases; Gastrointestinal Motil | 1980 |
[Evaluation of the action of drug agents on the tonus of the lower esophageal sphincter].
Topics: Atropine; Bicarbonates; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Duodenal Disease | 1978 |
[The therapy of gastroduodenal diseases. Results of a randomized double-blind study of gastroduodenal diseases with the new mono-substance viaben].
Topics: Adult; Aged; Double-Blind Method; Drug Evaluation; Female; Gastroenteritis; Humans; Male; Metoclopra | 1978 |
[Clinical experience with Paspertin in gastroenterology].
Topics: Biliary Dyskinesia; Clinical Trials as Topic; Gastrointestinal Diseases; Gastrointestinal Motility; | 1975 |
[Conservative therapy of upper gastrointestinal hemorrhage (prospective, randomized, controlled)].
Topics: Aluminum; Benzodiazepinones; Calcium; Cimetidine; Drug Therapy, Combination; Estrogens; Gastrointest | 1985 |
18 other studies available for metoclopramide and Peptic Ulcer
| Article | Year |
|---|---|
[A study on the effects of clinical drugs on lower esophageal sphincter pressure. Particularly on the relation with clinical drugs].
Topics: Alkalies; Calcium Channel Blockers; Domperidone; Esophagitis; Esophagogastric Junction; Histamine H2 | 1983 |
[Oculogyric crises as a side effect of metoclopramide].
Topics: Eye Movements; Female; Humans; Metoclopramide; Middle Aged; Parkinson Disease, Secondary; Peptic Ulc | 1984 |
[Conservative therapy of peptic ulcer].
Topics: Antacids; Benzodiazepinones; Cimetidine; Diazepam; Gastrointestinal Hormones; Humans; Hypnosis; Meto | 1980 |
[Gastronerton (metoclopramide) in gastrointestinal diseases. Clinical effect and tolerance].
Topics: Adult; Aged; Drug Evaluation; Drug Tolerance; Female; Gastrointestinal Diseases; Humans; Male; Metoc | 1980 |
[Diagnosis, prevention and treatment of postoperative reflux gastritis].
Topics: Aluminum Hydroxide; Anastomosis, Roux-en-Y; Antacids; Balneology; Benzocaine; Combined Modality Ther | 1994 |
[Conservative treatment of peptic ulcer disease (author's transl)].
Topics: Bismuth; Glycyrrhiza; Histamine H2 Antagonists; Humans; Metoclopramide; Peptic Ulcer; Plants, Medici | 1977 |
Symposium on peptic ulcer disease. 1. Medical treatment of peptic ulcer.
Topics: Animals; Antacids; Carbenoxolone; Cimetidine; Duodenal Ulcer; Guanidines; Humans; Metoclopramide; Mi | 1978 |
[Study of total gastric emptying using barium pearls].
Topics: Adolescent; Adult; Barium Sulfate; Gastric Emptying; Humans; Methods; Metoclopramide; Middle Aged; P | 1977 |
[Treatment of peptic ulcer with reglanom].
Topics: Humans; Metoclopramide; Peptic Ulcer | 1978 |
Relief of acute, persistent postvagotomy atony by metoclopramide.
Topics: Administration, Oral; Adult; Aged; Drug Evaluation; Female; Follow-Up Studies; Gastric Emptying; Hum | 1978 |
The treatment of dyspepsia.
Topics: Antacids; Bismuth; Carbenoxolone; Cimetidine; Dyspepsia; Esophagitis; Humans; Metoclopramide; Parasy | 1977 |
Withdrawal effects of metoclopramide.
Topics: Adult; Amenorrhea; Drug Therapy, Combination; Female; Humans; Metoclopramide; Peptic Ulcer; Substanc | 1991 |
Non-surgical treatment of acute upper gastrointestinal haemorrhage.
Topics: Acute Disease; Esophageal and Gastric Varices; Gastrointestinal Hemorrhage; Humans; Metoclopramide; | 1990 |
[The effect of metoclopramide on the acid and pepsin secretion of patients with chronic gastritis and peptic ulcer].
Topics: Adult; Chronic Disease; Drug Evaluation; Female; Gastric Acid; Gastric Juice; Gastritis; Histamine; | 1989 |
[Gastric evacuatory function in peptic ulcer studied using radionuclide research data].
Topics: Adolescent; Adult; Atropine; Female; Gastric Emptying; Gastrointestinal Transit; Humans; Iodine Radi | 1989 |
[Drugs modifying motility in ulcer therapy].
Topics: Cisapride; Gastrointestinal Motility; Humans; Metoclopramide; Peptic Ulcer; Piperidines; Pirenzepine | 1987 |
[Effect of metoclopramide, papaverine and gastrozepin on the myoelectrical activity of the stomach and small intestine].
Topics: Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzodiazepinones; Drug Evaluation; Electromyography; Fe | 1985 |
[New views on the physiopathology of peptic ulcer].
Topics: Duodenal Ulcer; Gastrins; Gastritis; Histamine H1 Antagonists; Humans; Metoclopramide; Peptic Ulcer; | 1974 |