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metoclopramide and Ocular Hypotension

metoclopramide has been researched along with Ocular Hypotension in 2 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Ocular Hypotension: Abnormally low intraocular pressure often related to chronic inflammation (uveitis).

Research Excerpts

ExcerptRelevanceReference
"Topically unilaterally applied lisuride caused dose-related lowering of intraocular pressure in ipsilateral (treated) but not in contralateral eyes of normal rabbits."7.70Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. ( Chu, TC; Ogidigben, MJ; Potter, DE, 1998)
"Topically unilaterally applied lisuride caused dose-related lowering of intraocular pressure in ipsilateral (treated) but not in contralateral eyes of normal rabbits."3.70Lisuride acts at multiple sites to induce ocular hypotension and mydriasis. ( Chu, TC; Ogidigben, MJ; Potter, DE, 1998)
"The dopamine (DA2) receptor agonist 2,10,11-trihydroxy-N-n-propylnoraporphine (TNPA) was tested for effects on 1) intraocular pressure (IOP), 2) aqueous humor flow rate, 3) electrically induced contractions of the cat nictitating membrane, 4) 3H-NE release from isolated rabbit iris-ciliary bodies and 5) cAMP accumulation in the isolated rabbit iris-ciliary body."3.68Ocular hypotensive action of a dopaminergic (DA2) agonist, 2,10,11-trihydroxy-N-n-propylnoraporphine. ( Chu, TC; Ogidigben, M; Potter, DE, 1993)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ogidigben, M1
Chu, TC2
Potter, DE2
Ogidigben, MJ1

Other Studies

2 other studies available for metoclopramide and Ocular Hypotension

ArticleYear
Ocular hypotensive action of a dopaminergic (DA2) agonist, 2,10,11-trihydroxy-N-n-propylnoraporphine.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:2

    Topics: Animals; Aporphines; Aqueous Humor; Cats; Ciliary Body; Cyclic AMP; Dopamine Agents; Drug Interactio

1993
Lisuride acts at multiple sites to induce ocular hypotension and mydriasis.
    Pharmacology, 1998, Volume: 57, Issue:5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1998