metoclopramide has been researched along with Neuroleptic Malignant Syndrome in 21 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case of metoclopramide-induced neuroleptic malignant syndrome with cerebrospinal fluid (CSF) lactic acidosis was reported." | 8.78 | [A case of metoclopramide-induced neuroleptic malignant syndrome with cerebrospinal fluid lactic acidosis]. ( Fujishima, M; Nagashima, A; Okada, Y; Sadoshima, S; Takada, Y; Yao, H, 1991) |
| "A patient with myeloma nephropathy and acute, probably diclofenac-induced renal failure developed a neuroleptic malignant syndrome (NMS) during treatment with metoclopramide and neuroleptics." | 7.68 | [Malignant neuroleptic syndrome under metoclopramide and neuroleptics in anuria]. ( Herren, T; Krähenbühl, S; Raisin, J, 1993) |
| " The syndrome was associated with metoclopramide antiemetic therapy given for post-operative nausea and vomiting." | 7.68 | Neuroleptic malignant syndrome associated with metoclopramide antiemetic therapy. ( Bakri, YN; Kawi, Z; Khan, R; Subhi, J, 1992) |
| "We report a case of fulminant neuroleptic malignant syndrome in a man aged 70 developing within 12 hours of starting six-hourly intravenous metoclopramide." | 7.68 | Fulminant metoclopramide induced neuroleptic malignant syndrome rapidly responsive to intravenous dantrolene. ( Henderson, A; Longdon, P, 1991) |
| "Neuroleptic malignant syndrome (NMS) associated with metoclopramide is rare." | 7.68 | Neuroleptic malignant syndrome induced by metoclopramide. ( Alif Cherif, A; Donnet, A; Dumont, JC; Harle, JR, 1991) |
| "The case of neuroleptic malignant syndrome presented was associated with the use of metoclopramide, a dopamine-blocking agent, which is normally used in nonpsychiatric patients." | 7.67 | Neuroleptic malignant syndrome associated with metoclopramide. ( Patterson, JF, 1988) |
| "A case of metoclopramide-induced neuroleptic malignant syndrome with cerebrospinal fluid (CSF) lactic acidosis was reported." | 4.78 | [A case of metoclopramide-induced neuroleptic malignant syndrome with cerebrospinal fluid lactic acidosis]. ( Fujishima, M; Nagashima, A; Okada, Y; Sadoshima, S; Takada, Y; Yao, H, 1991) |
| "A patient with myeloma nephropathy and acute, probably diclofenac-induced renal failure developed a neuroleptic malignant syndrome (NMS) during treatment with metoclopramide and neuroleptics." | 3.68 | [Malignant neuroleptic syndrome under metoclopramide and neuroleptics in anuria]. ( Herren, T; Krähenbühl, S; Raisin, J, 1993) |
| " The syndrome was associated with metoclopramide antiemetic therapy given for post-operative nausea and vomiting." | 3.68 | Neuroleptic malignant syndrome associated with metoclopramide antiemetic therapy. ( Bakri, YN; Kawi, Z; Khan, R; Subhi, J, 1992) |
| "Treatment with dantrolene sodium combined with a forced alkaline diuresis resulted in a full recovery." | 1.29 | Postoperative neuroleptic malignant syndrome. ( Matthews, EE; Shaw, A, 1995) |
| "The neuroleptic malignant syndrome is a serious and potentially fatal complication of neuroleptic and other dopamine antagonist drugs that are commonly used in symptom control in advanced cancer." | 1.28 | The neuroleptic malignant syndrome. ( O'Neill, WM, 1990) |
| " An increased index of suspicion for early diagnosis of this condition and adjustment of metoclopramide dosing in patients with renal failure are emphasized." | 1.27 | Neuroleptic malignant-like syndrome induced by metoclopramide. ( Samie, MR, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (28.57) | 18.7374 |
| 1990's | 12 (57.14) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 2 (9.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kocyigit, SE | 1 |
| Soysal, P | 1 |
| Isik, AT | 1 |
| Supariwala, A | 1 |
| Kant, G | 1 |
| Jean, RE | 1 |
| Stein, MH | 1 |
| Sorscher, M | 1 |
| Caroff, SN | 2 |
| Le Couteur, DG | 1 |
| Kay, T | 1 |
| Shaw, A | 1 |
| Matthews, EE | 1 |
| Shintani, S | 1 |
| Shiigai, T | 1 |
| Tsuchiya, K | 1 |
| Kikuchi, M | 1 |
| Mann, SC | 1 |
| Krähenbühl, S | 1 |
| Raisin, J | 1 |
| Herren, T | 1 |
| Fujita, Y | 1 |
| Yasukawa, T | 1 |
| Mihira, M | 1 |
| Sasaki, T | 1 |
| Yokoya, S | 1 |
| Nonino, F | 1 |
| Campomori, A | 1 |
| Bakri, YN | 1 |
| Khan, R | 1 |
| Subhi, J | 1 |
| Kawi, Z | 1 |
| Henderson, A | 1 |
| Longdon, P | 1 |
| Donnet, A | 1 |
| Harle, JR | 1 |
| Dumont, JC | 1 |
| Alif Cherif, A | 1 |
| Nagashima, A | 1 |
| Yao, H | 1 |
| Okada, Y | 1 |
| Sadoshima, S | 1 |
| Takada, Y | 1 |
| Fujishima, M | 1 |
| O'Neill, WM | 1 |
| Brower, RD | 1 |
| Dreyer, CF | 1 |
| Kent, TA | 1 |
| Cassidy, T | 1 |
| Bansal, SK | 1 |
| Patterson, JF | 1 |
| Samie, MR | 1 |
| Friedman, LS | 1 |
| Weinrauch, LA | 1 |
| D'Elia, JA | 1 |
| Robinson, MB | 1 |
| Kennett, RP | 1 |
| Harding, AE | 1 |
| Legg, NJ | 1 |
| Clarke, B | 1 |
2 reviews available for metoclopramide and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Metoclopramide in a patient with renal failure may be an increased risk of neuroleptic malignant syndrome.
Topics: Female; Humans; Kidney Failure, Chronic; Metoclopramide; Middle Aged; Neuroleptic Malignant Syndrome | 1996 |
[A case of metoclopramide-induced neuroleptic malignant syndrome with cerebrospinal fluid lactic acidosis].
Topics: Acidosis, Lactic; Adult; Brain; Female; Humans; Lactates; Metoclopramide; Neuroleptic Malignant Synd | 1991 |
19 other studies available for metoclopramide and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Neuroleptic malignant syndrome associated with only one dose of metoclopramide in an older adult.
Topics: Age Factors; Aged; Antipsychotic Agents; Humans; Male; Metoclopramide; Neuroleptic Malignant Syndrom | 2017 |
Neuroleptic malignant syndrome with metoclopramide overdose coexisting with Clostridium difficile diarrhea.
Topics: Diarrhea; Dopamine Antagonists; Enterocolitis, Pseudomembranous; Humans; Male; Metoclopramide; Middl | 2011 |
Neuroleptic malignant syndrome induced by metoclopramide in an infant with Freeman-Sheldon syndrome.
Topics: Abnormalities, Multiple; Dopamine Antagonists; Female; Humans; Infant; Metoclopramide; Neuroleptic M | 2006 |
Delayed neuroleptic malignant syndrome following cessation of prolonged therapy with metoclopramide.
Topics: Humans; Male; Metoclopramide; Middle Aged; Neuroleptic Malignant Syndrome; Time Factors | 1995 |
Postoperative neuroleptic malignant syndrome.
Topics: Child; Dantrolene; Diuresis; Droperidol; Female; Humans; Hyponatremia; Metoclopramide; Neuroleptic M | 1995 |
Hyperventilation alternating with apnea in neuroleptic malignant syndrome associated with metoclopramide and cisapride.
Topics: Aged; Apnea; Brain; Cisapride; Fatal Outcome; Humans; Hyperventilation; Male; Metoclopramide; Neurol | 1995 |
Neuroleptic malignant syndrome and malignant hyperthermia.
Topics: Adolescent; Disease Susceptibility; Humans; Male; Malignant Hyperthermia; Metoclopramide; Neurolepti | 1993 |
[Malignant neuroleptic syndrome under metoclopramide and neuroleptics in anuria].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Anuria; Chlorpromazine; Female; Humans; Kidney | 1993 |
Neuroleptic malignant syndrome associated with metoclopramide.
Topics: Aged; Dopamine Antagonists; Female; Humans; Metoclopramide; Neuroleptic Malignant Syndrome | 1999 |
Neuroleptic malignant syndrome associated with metoclopramide antiemetic therapy.
Topics: Adenocarcinoma; Antiemetics; Female; Humans; Metoclopramide; Middle Aged; Nausea; Neuroleptic Malign | 1992 |
Fulminant metoclopramide induced neuroleptic malignant syndrome rapidly responsive to intravenous dantrolene.
Topics: Aged; Dantrolene; Humans; Infusions, Intravenous; Male; Metoclopramide; Neuroleptic Malignant Syndro | 1991 |
Neuroleptic malignant syndrome induced by metoclopramide.
Topics: Aged; Humans; Male; Metoclopramide; Neuroleptic Malignant Syndrome | 1991 |
The neuroleptic malignant syndrome.
Topics: Adult; Female; Haloperidol; Humans; Metoclopramide; Neuroleptic Malignant Syndrome; Postoperative Co | 1990 |
Neuroleptic malignant syndrome in a child treated with metoclopramide for chemotherapy-related nausea.
Topics: Child, Preschool; Humans; Male; Metoclopramide; Nausea; Neuroleptic Malignant Syndrome | 1989 |
Neuroleptic malignant syndrome associated with metoclopramide.
Topics: Aged; Humans; Male; Metoclopramide; Neuroleptic Malignant Syndrome | 1988 |
Neuroleptic malignant syndrome associated with metoclopramide.
Topics: Humans; Male; Metoclopramide; Middle Aged; Neuroleptic Malignant Syndrome | 1988 |
Neuroleptic malignant-like syndrome induced by metoclopramide.
Topics: Aged; Creatine Kinase; Drug Administration Schedule; Humans; Male; Metoclopramide; Neuroleptic Malig | 1987 |
Metoclopramide-induced neuroleptic malignant syndrome.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Humans; Metoclopramide; Nausea; Neuroleptic Malignant Synd | 1987 |
Neuroleptic malignant syndrome associated with metoclopramide.
Topics: Humans; Male; Metoclopramide; Middle Aged; Nausea; Neuroleptic Malignant Syndrome | 1985 |