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metoclopramide and Muscle Contraction

metoclopramide has been researched along with Muscle Contraction in 75 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
" Erythromycin administration is associated with gastrointestinal problems, disturbed gastrointestinal motility and emesis."7.68Effects of cholinoceptor and 5-hydroxytryptamine3 receptor antagonism on erythromycin-induced canine intestinal motility disruption and emesis. ( Pilot, MA; Qin, XY; Scott, M; Thompson, H, 1993)
" Erythromycin administration is associated with gastrointestinal problems, disturbed gastrointestinal motility and emesis."3.68Effects of cholinoceptor and 5-hydroxytryptamine3 receptor antagonism on erythromycin-induced canine intestinal motility disruption and emesis. ( Pilot, MA; Qin, XY; Scott, M; Thompson, H, 1993)
"The effects of metoclopramide on smooth muscle contraction and on release of acetylcholine were studied in the guinea-pig myenteric plexus longitudinal muscle preparation."3.66The effects of metoclopramide on acetylcholine release and on smooth muscle response in the isolated guinea-pig ileum. ( Kilbinger, H; Kruel, R; Pfeuffer-Friederich, I; Wessler, I, 1982)
"Ethosuximide is a drug used for the treatment of absence seizures."1.33Neostigmine, but not metoclopramide, abolishes ethosuximide-induced functional gastrointestinal disturbances. ( Kostadinova, I; Krastev, A; Sirakov, V; Turiiski, V, 2005)
"Renzapride (5f) was identified for further evaluation for which both enantiomers had an identical pharmacological profile, as did an azatricyclic 9b, which contained a combination of the steric bulk of the two separate enantiomers."1.29Substituted benzamides with conformationally restricted side chains. 5. Azabicyclo[x.y.z] derivatives as 5-HT4 receptor agonists and gastric motility stimulants. ( Hadley, MS; Joiner, KT; King, FD; Martin, RT; Sanger, GJ; Smith, DM; Smith, GE; Smith, P; Turner, DH; Watts, EA, 1993)
"Metoclopramide has been reported to sensitize postjunctional muscarinic receptors, however, ML-1035 did not enhance acetylcholine-induced contractions."1.29Analysis of neurogenic contractions induced by ML-1035 and other benzamides in the guinea-pig non-stimulated isolated ileum. ( Ahmed, NK; Butler, BT; Elsea, SH; Linnik, MD, 1994)
"Quinpirole did not enhance contractile responses to acetylcholine and carbachol, but in high concentrations induced contractions in unstimulated preparations."1.28Influence of the DA2-receptor agonist quinpirole on the guinea pig ileum. ( Guenaneche, F; Lefebvre, RA, 1990)
"Metoclopramide was compared with bethanechol chloride and a control substance in a random double blind study."1.27Effects of metoclopramide on detrusor function. ( Mitchell, WC; Venable, DD, 1985)
"Metoclopramide has a dual effect on intestinal smooth muscle."1.26The effects of metoclopramide in modifying the response of isolated guinea-pig ileum to various agonists. ( Bury, RW; Mashford, ML, 1976)
"Pretreatment with metoclopramide or with pimozide shifted the volume-pressure diagram of the stomach to the left; that is, at any given volume the pressure was greater after than before these drugs."1.26Dopamine as a possible neurotransmitter in gastric relaxation. ( Valenzuela, JE, 1976)
"Gallstone dyspepsia is essentially a functional disease--a disorder of gastroduodenal motility."1.25Cholecystectomy and gallstone dyspepsia. Clinical and physiological study of a symptom complex. ( Johnson, AG, 1975)

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-199052 (69.33)18.7374
1990's16 (21.33)18.2507
2000's6 (8.00)29.6817
2010's1 (1.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Youssefyeh, RD1
Campbell, HF1
Airey, JE1
Klein, S1
Schnapper, M1
Powers, M1
Woodward, R1
Rodriguez, W1
Golec, S1
Studt, W1
King, FD2
Hadley, MS1
Joiner, KT1
Martin, RT1
Sanger, GJ5
Smith, DM1
Smith, GE1
Smith, P1
Turner, DH1
Watts, EA1
Sasho, S1
Obase, H1
Ichikawa, S1
Kitazawa, T1
Nonaka, H1
Yoshizaki, R1
Ishii, A1
Shuto, K1
Kasirer, MY1
Welsh, C1
Pan, J1
Shifrin, Y1
Belik, J1
Yau, KI2
Hwang, TL1
Saito, M1
Shibata, O1
Yamaguchi, M1
Yoshimura, M1
Makita, T1
Harada, N1
Niwa, M1
Sumikawa, K1
Sirakov, V1
Krastev, A1
Kostadinova, I1
Turiiski, V1
Bassil, AK1
Dass, NB1
Murray, CD1
Muir, A1
Yamada, K2
Iizuka, M2
Takaiti, O1
Lefebvre, RA2
Willems, JL1
Bogaert, MG1
Spedding, M1
Costall, B5
Naylor, RJ6
Tan, CC2
Ishizawa, M1
Mangel, AW1
Stavorski, JR1
Pendleton, RG1
Lukanov, Y1
Milieva, E1
Stefanova, M1
Sveshtarova, M1
Baldi, F1
Ferrarini, F1
Milazzo, G1
Miglioli, M1
Zar, MA1
Ebong, O1
Bateman, DN1
Kilbinger, H2
Kruel, R1
Pfeuffer-Friederich, I2
Wessler, I1
Meshkinpour, H1
Hoehler, F1
Bernick, D1
Buerger, AA1
Fosbraey, P2
Hird, MF1
Johnson, ES2
Maroy, B1
Chermet, J1
Tubiana, JM1
Chalut, J1
Odinot, JM1
Buchheit, KH2
Buhl, T1
Linnik, MD1
Butler, BT2
Elsea, SH1
Ahmed, NK1
Desai, KM1
Warner, TD1
Vane, JR1
Qin, XY1
Pilot, MA1
Thompson, H1
Scott, M1
Eglen, RM1
Bley, K1
Bonhaus, DW1
Clark, RD1
Hegde, SS1
Johnson, LG1
Leung, E1
Wong, EH1
Gaster, LM1
Jennings, AJ1
Joiner, GF1
Mulholland, KR1
Rahman, SK1
Starr, S1
Wyman, PA1
Wardle, KA1
Ellis, ES1
Chaudhuri, L1
Ganguly, DK1
Langer, JC1
Bramlett, G1
Ko, FN1
Chien, CH1
Nieto, JE2
Rakestraw, PC1
Snyder, JR2
Vatistas, NJ2
Van Hoogmoed, LM1
Spier, SJ1
Timmerman, BL1
Bury, RW1
Mashford, ML1
Valenzuela, JE1
Anderson, JD1
Day, MD1
Watson, JK1
Fontaine, J6
Famaey, JP2
Reuse, J4
Seaman, I1
Johnson, AG2
Hay, AM2
Man, WK1
Ormsbee, HS2
Bass, P1
Silvey, G1
Houston, DM1
Borcherding, DR1
Vaughn, VL1
McPhail, AT1
Radzik, DM1
Wynberg, H1
ten Hoeve, W1
van Echten, E1
Uma, S1
Sahin-Erdemli, I1
Elswood, CJ1
Bunce, KT1
Humphrey, PP1
Guenaneche, F1
Gunning, SJ5
Mitchell, WC1
Venable, DD1
Engel, G1
Richardson, BP1
Bradbury, AJ1
Lombardi, DM1
Grous, M1
Fine, CF1
Barone, FC1
Fowler, PJ1
Phyall, WB1
Rush, JA1
Tattersall, FD1
McKirdy, HC1
Marshall, RW1
Griffin, P1
Lafi, MA1
Leake, LD1
Domeney, AM1
Kelly, ME1
Nohria, V1
Owera-Atepo, JB1
Simpson, KM1
Tattersall, D1
Mori, M1
Hoshino, Y1
Obara, H1
Iwai, S1
Vogelberg, KH1
Dalügge, A1
Bou, J2
Fernández, AG1
Jauregui, JM1
Massingham, R2
Gidda, JS1
Buyniski, JP1
Schuurkes, JA2
Van Nueten, JM2
Van Daele, PG1
Reyntjens, AJ1
Janssen, PA1
Lobbezoo, MW1
Janszen, FH1
Tulp, MT1
Zwagemakers, JM1
Roberts, DJ1
Helsen, LF1
Hradsky, M1
Stockbrügger, R1
Birtley, RD1
Baines, MW1
Reuse, JJ2

Trials

1 trial available for metoclopramide and Muscle Contraction

ArticleYear
[Comparative radiologic study of 2 agents modifying digestive behavior].
    Medecine & chirurgie digestives, 1980, Volume: 9, Issue:2

    Topics: Adult; Aged; Benzimidazoles; Digestive System; Domperidone; Duodenum; Female; Humans; Male; Metoclop

1980

Other Studies

74 other studies available for metoclopramide and Muscle Contraction

ArticleYear
Development of high-affinity 5-HT3 receptor antagonists. 2. Two novel tricyclic benzamides.
    Journal of medicinal chemistry, 1992, Mar-06, Volume: 35, Issue:5

    Topics: Amides; Animals; Antiemetics; Benzamides; Benzofurans; Bridged Bicyclo Compounds; Bridged Bicyclo Co

1992
Substituted benzamides with conformationally restricted side chains. 5. Azabicyclo[x.y.z] derivatives as 5-HT4 receptor agonists and gastric motility stimulants.
    Journal of medicinal chemistry, 1993, Mar-19, Volume: 36, Issue:6

    Topics: Animals; Aza Compounds; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocycl

1993
Synthesis of 2-imidazolidinylidenepropanedinitrile derivatives as stimulators of gastrointestinal motility.
    Journal of medicinal chemistry, 1993, Mar-05, Volume: 36, Issue:5

    Topics: Animals; Cholinesterase Inhibitors; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Il

1993
Metoclopramide does not increase gastric muscle contractility in newborn rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Mar-01, Volume: 306, Issue:5

    Topics: Animals; Animals, Newborn; Dopamine Antagonists; Electrophysiological Phenomena; Gastrointestinal Tr

2014
The nonadrenergic noncholinergic system can modulate the effect of prokinetic agents on contractile response of isolated guinea-pig trachea segments to electrical field stimulation.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2002, Volume: 101, Issue:10

    Topics: Animals; Autonomic Nervous System; Chymotrypsin; Cisapride; Dopamine Antagonists; Electric Stimulati

2002
Metoclopramide causes airway smooth muscle relaxation through inhibition of muscarinic M3 receptor in the rat trachea.
    Anesthesia and analgesia, 2004, Volume: 98, Issue:5

    Topics: Animals; Antiemetics; Carbachol; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Metoclopra

2004
Neostigmine, but not metoclopramide, abolishes ethosuximide-induced functional gastrointestinal disturbances.
    Pharmacology, 2005, Volume: 75, Issue:4

    Topics: Animals; Anticonvulsants; Cholinesterase Inhibitors; Dopamine Antagonists; Dose-Response Relationshi

2005
Prokineticin-2, motilin, ghrelin and metoclopramide: prokinetic utility in mouse stomach and colon.
    European journal of pharmacology, 2005, Nov-07, Volume: 524, Issue:1-3

    Topics: Animals; Colon; Dose-Response Relationship, Drug; Electric Stimulation; Gastrointestinal Hormones; G

2005
Effect of trimebutine maleate on bethanechol-induced contractions of gastrointestinal tract in conscious and anaesthetized dogs.
    Japanese journal of pharmacology, 1983, Volume: 33, Issue:2

    Topics: Animals; Atropine; Benzoates; Bethanechol; Bethanechol Compounds; Digestive System Physiological Phe

1983
Inhibitory effect of dopamine on canine gastric fundus.
    Naunyn-Schmiedeberg's archives of pharmacology, 1984, Volume: 326, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Cocaine; Dogs; Dopamine; Electric Stimulation; Female; Gastri

1984
Effects of metoclopramide and isoprenaline in the rat vas deferens; interactions with alpha-adrenoceptors.
    British journal of pharmacology, 1980, Volume: 71, Issue:1

    Topics: Animals; Benzamides; Clonidine; Electric Stimulation; In Vitro Techniques; Isoproterenol; Male; Meto

1980
Neuronally mediated contraction responses of guinea-pig stomach smooth muscle preparations: modification by benzamide derivatives does not reflect a dopamine antagonist action.
    European journal of pharmacology, 1984, Jun-15, Volume: 102, Issue:1

    Topics: Animals; Benzamides; Domperidone; Electric Stimulation; Guinea Pigs; Haloperidol; In Vitro Technique

1984
[Effects of trimebutine and metoclopramide on colonic motility in the guinea pig].
    Nihon Heikatsukin Gakkai zasshi, 1984, Volume: 20, Issue:5

    Topics: Animals; Benzoates; Colon; Dose-Response Relationship, Drug; Drug Interactions; Gastrointestinal Mot

1984
Effects of bethanechol, metoclopramide, and domperidone on antral contractions in cats and dogs.
    Digestion, 1983, Volume: 28, Issue:4

    Topics: Animals; Bethanechol Compounds; Cats; Dogs; Domperidone; Metoclopramide; Models, Biological; Muscle

1983
Rimetin effect on gastrointestinal tract smooth muscles in normal conditions and following exposure to X-rays.
    Folia medica, 1982, Volume: 24, Issue:1

    Topics: Animals; Antiemetics; Female; Guinea Pigs; In Vitro Techniques; Male; Metoclopramide; Muscle Contrac

1982
[Preliminary findings on the effects of a new antispastic drug (N-diethyl-methyl-ammonium ethyl bromide P-[2-(N-octyloxy)-benzoyl]-aminobenzoate) on the motor activity of the human gastric antrum].
    La Clinica terapeutica, 1980, Jul-31, Volume: 94, Issue:2

    Topics: 4-Aminobenzoic Acid; Adult; Aminobenzoates; Drug Evaluation; Female; Gastrointestinal Motility; Huma

1980
Effect of metoclopramide in guinea-pig ileum longitudinal muscle: evidence against dopamine-mediation.
    Gut, 1982, Volume: 23, Issue:1

    Topics: Animals; Cholinergic Fibers; Dopamine; Dopamine Antagonists; Guinea Pigs; Ileum; Male; Metoclopramid

1982
The effects of metoclopramide on acetylcholine release and on smooth muscle response in the isolated guinea-pig ileum.
    Naunyn-Schmiedeberg's archives of pharmacology, 1982, Volume: 319, Issue:3

    Topics: Acetylcholine; Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Metoclopramid

1982
Electrical control activity in the sigmoid colon: effect of metoclopramide.
    American journal of proctology, gastroenterology & colon & rectal surgery, 1981, Volume: 32, Issue:10

    Topics: Aged; Colon, Sigmoid; Electric Stimulation; Electrodes, Implanted; Female; History, 16th Century; Hu

1981
The effects of some dopamine antagonists on cholinergic mechanisms in the guinea-pig ileum.
    Journal of autonomic pharmacology, 1980, Volume: 1, Issue:1

    Topics: Acetylcholine; Animals; Dopamine Antagonists; Guinea Pigs; Ileum; Imidazoles; In Vitro Techniques; M

1980
Modulatory action on the twitch responses of the guinea-pig ileum of endogenous substances released by high frequency electrical stimulation.
    European journal of pharmacology, 1980, Oct-31, Volume: 67, Issue:4

    Topics: Acetylcholine; Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Metoclo

1980
Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: 4-Aminobenzoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Benzamides; Binding

1994
Analysis of neurogenic contractions induced by ML-1035 and other benzamides in the guinea-pig non-stimulated isolated ileum.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:6

    Topics: Acetylcholine; Animals; Benzamides; Dose-Response Relationship, Drug; Drug Interactions; Female; Gui

1994
5-HT3 receptors do not mediate vagally-induced relaxation or contraction of the isolated stomach of the guinea-pig.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: Animals; Dimethylphenylpiperazinium Iodide; Electric Stimulation; In Vitro Techniques; Male; Metoclo

1994
Effects of cholinoceptor and 5-hydroxytryptamine3 receptor antagonism on erythromycin-induced canine intestinal motility disruption and emesis.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: Animals; Atropine; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; C

1993
RS 23597-190: a potent and selective 5-HT4 receptor antagonist.
    British journal of pharmacology, 1993, Volume: 110, Issue:1

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Animals; Blood Pressure; Electrophysiology; Female; Guinea Pigs

1993
(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide.
    Journal of medicinal chemistry, 1993, Dec-10, Volume: 36, Issue:25

    Topics: Animals; Dioxanes; Guinea Pigs; Metoclopramide; Muscle Contraction; Piperidines; Receptors, Serotoni

1993
Involvement of gamma-aminobutyric acid in the stimulatory effect of metoclopramide on gastrointestinal motility.
    Life sciences, 1994, Volume: 54, Issue:4

    Topics: Aminobutyrates; Animals; Arecoline; Bicuculline; Drug Interactions; Ethylenediamines; gamma-Aminobut

1994
Effect of prokinetic agents on ileal contractility in a rabbit model of gastroschisis.
    Journal of pediatric surgery, 1997, Volume: 32, Issue:4

    Topics: Abdominal Muscles; Animals; Animals, Newborn; Bethanechol; Cisapride; Congenital Abnormalities; Eryt

1997
Effects of prokinetic agents on contractile responses to electrical field stimulation of isolated guinea pig trachea.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1999, Volume: 98, Issue:8

    Topics: Animals; Cisapride; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Metoclopramide; Mu

1999
In vitro effects of erythromycin, lidocaine, and metoclopramide on smooth muscle from the pyloric antrum, proximal portion of the duodenum, and middle portion of the jejunum of horses.
    American journal of veterinary research, 2000, Volume: 61, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Dopamine Antagonists; Duodenum; Erythromycin; Gastrointestinal Agen

2000
Use of an extracorporeal circuit to evaluate effects of intraluminal distention and decompression on the equine jejunum.
    American journal of veterinary research, 2002, Volume: 63, Issue:2

    Topics: Albumins; Animals; Cisapride; Erythromycin; Extracorporeal Circulation; Horses; Intestinal Mucosa; J

2002
The effects of metoclopramide in modifying the response of isolated guinea-pig ileum to various agonists.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 197, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Barium; Female; Guanethidine; Guinea Pigs; Histamine; Hydrogen-Ion

1976
Dopamine as a possible neurotransmitter in gastric relaxation.
    Gastroenterology, 1976, Volume: 71, Issue:6

    Topics: Animals; Dogs; Dopamine; Dopamine Antagonists; Gastrointestinal Motility; Metoclopramide; Muscle Con

1976
Potentiation by metoclopramide of responses to cholinergic nerve stimulation in the isolated gastric fundus preparation of the rat [proceedings].
    The Journal of pharmacy and pharmacology, 1977, Volume: 29 Suppl

    Topics: Animals; Electric Stimulation; In Vitro Techniques; Metoclopramide; Muscle Contraction; Muscle, Smoo

1977
Metoclopramide reverses inhibitions of electrically-induced contractions of guinea-pig isolated ileum by anti-inflammatory drugs.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Metoclopr

1979
The inhibitory effects of sex steroid hormones on electrically-induced contractions of the guinea-pig isolated ileum.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:3

    Topics: Animals; Ceruletide; Electric Stimulation; Ethinyl Estradiol; Guinea Pigs; Ileum; In Vitro Technique

1979
Cholecystectomy and gallstone dyspepsia. Clinical and physiological study of a symptom complex.
    Annals of the Royal College of Surgeons of England, 1975, Volume: 56, Issue:2

    Topics: Adult; Bilirubin; Cholecystectomy; Cholelithiasis; Digestive System; Duodenal Diseases; Dyspepsia; F

1975
Effect of metoclopramide on guinea pig stomach: critical dependence on intrinsic stores of acetylcholine.
    Gastroenterology, 1979, Volume: 76, Issue:3

    Topics: Acetylcholine; Animals; Electric Stimulation; Gastric Mucosa; Gastrointestinal Motility; Guinea Pigs

1979
Pharmacological analysis of the effects of metoclopramide on the transmurally stimulated guinea-pig ileum.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 242, Issue:1

    Topics: Animals; Calcium; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Metoc

1979
Pharmacological analysis of the effects of substituted benzamides on the isolated guinea-pig ileum. Study of metoclopramide, sulpiride, bromopride, tiapride and sultopride.
    Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 235, Issue:1

    Topics: Acetylcholine; Animals; Benzamides; Drug Interactions; Female; Guinea Pigs; Histamine; Ileum; In Vit

1978
Pharmacological analysis of the effects of metoclopramide on the guinea pig isolated stomach.
    Gastroenterology, 1977, Volume: 72, Issue:5 Pt 1

    Topics: Acetylcholine; Animals; Cholinergic Fibers; Guinea Pigs; Hexamethonium Compounds; Male; Metocloprami

1977
Gastroduodenal motor gradients in the dog after pyloroplasty.
    The American journal of physiology, 1976, Volume: 230, Issue:2

    Topics: Animals; Citrates; Dogs; Duodenum; Fats; Female; Food; Gastrointestinal Motility; Male; Methacholine

1976
The resolution, isolation, and pharmacological characterization of the enantiomers of a benzamide containing a chiral sulfoxide.
    Chirality, 1992, Volume: 4, Issue:3

    Topics: Animals; Benzamides; Guinea Pigs; Ileum; In Vitro Techniques; Male; Metoclopramide; Muscle Contracti

1992
The effects of serotonin (5-HT) on twitch contractions induced by electrical stimulation of guinea-pig common bile duct.
    Archives internationales de physiologie, de biochimie et de biophysique, 1991, Volume: 99, Issue:6

    Topics: Acetylcholine; Animals; Bile Ducts; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques;

1991
Identification of putative 5-HT4 receptors in guinea-pig ascending colon.
    European journal of pharmacology, 1991, Apr-17, Volume: 196, Issue:2

    Topics: Animals; Colon; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Methysergide; Metoclo

1991
Influence of the DA2-receptor agonist quinpirole on the guinea pig ileum.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2

    Topics: Acetylcholine; Animals; Carbachol; Dopamine; Dopamine Agents; Drug Interactions; Electric Stimulatio

1990
The effects of various pharmacological agents on the metoclopramide-induced increase in cholinergic-mediated contractions of rat isolated forestomach.
    European journal of pharmacology, 1985, Aug-15, Volume: 114, Issue:2

    Topics: Acetylcholine; Animals; Electric Stimulation; In Vitro Techniques; Male; Metoclopramide; Muscle Cont

1985
5-Hydroxytryptamine can antagonize the ability of metoclopramide and SCH 23390 to enhance electrical field stimulation-evoked contractions of guinea-pig isolated stomach muscle.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:1

    Topics: Animals; Antipsychotic Agents; Benzazepines; Electric Stimulation; Guinea Pigs; In Vitro Techniques;

1985
Effects of metoclopramide on detrusor function.
    The Journal of urology, 1985, Volume: 134, Issue:4

    Topics: Animals; Bethanechol; Bethanechol Compounds; Dogs; Double-Blind Method; Female; Metoclopramide; Musc

1985
Effects of metoclopramide and domperidone on cholinergically mediated contractions of human isolated stomach muscle.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:9

    Topics: Acetylcholine; Atropine; Carbachol; Domperidone; Electric Stimulation; Humans; In Vitro Techniques;

1985
5-Hydroxytryptamine receptor antagonism by metoclopramide and ICS 205-930 in the guinea-pig leads to enhancement of contractions of stomach muscle strips induced by electrical field stimulation and facilitation of gastric emptying in-vivo.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:9

    Topics: Animals; Electric Stimulation; Gastric Emptying; Guinea Pigs; In Vitro Techniques; Indoles; Male; Me

1985
Evidence that 5-hydroxytryptamine may exert both facilitatory and inhibitory control of electrical field stimulation-evoked contractions in longitudinal muscle taken from the body of guinea-pig stomach.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Electric Stimulation; Fenclonine; Guinea Pigs; In Vitro Techniques; Ma

1986
DA1 receptor mediates dopamine-induced relaxation of opossum lower esophageal sphincter in vitro.
    Gastroenterology, 1986, Volume: 91, Issue:3

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Apomorphine; Aporphines; Benzaz

1986
Modification of electrical field stimulation-induced contractions in the guinea-pig ileum by metoclopramide and ICS 205-930 depends on the integrity of the mucosa.
    The Journal of pharmacy and pharmacology, 1986, Volume: 38, Issue:11

    Topics: Animals; Drug Interactions; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Indoles;

1986
Effect of drugs, hormones and electrical field stimulation on isolated muscle strips from human choledochoduodenal junction.
    Quarterly journal of experimental physiology (Cambridge, England), 1987, Volume: 72, Issue:2

    Topics: Acetylcholine; Ampulla of Vater; Atropine; Bile Ducts; Duodenum; Electric Stimulation; Gastrointesti

1987
Activation of a myenteric 5-hydroxytryptamine-like receptor by metoclopramide.
    The Journal of pharmacy and pharmacology, 1987, Volume: 39, Issue:6

    Topics: Acetylcholine; Animals; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Indoles; Male; Metoc

1987
Actions of dopamine and related amines on reserpinized and chronically denervated vasa deferentia of the rat.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1988, Volume: 89, Issue:2

    Topics: Amines; Animals; Denervation; Dopamine; Guanethidine; In Vitro Techniques; Male; Metoclopramide; Mus

1988
The action of dazopride to enhance gastric emptying and block emesis.
    Neuropharmacology, 1987, Volume: 26, Issue:7A

    Topics: Animals; Benzamides; Callitrichinae; Dopamine Antagonists; Electric Stimulation; Ferrets; Gastric Em

1987
Two types of receptors for 5-hydroxytryptamine on the cholinergic nerves of the guinea-pig myenteric plexus.
    British journal of pharmacology, 1985, Volume: 85, Issue:2

    Topics: Acetylcholine; Animals; Binding, Competitive; Cocaine; Electric Stimulation; Female; Guinea Pigs; Ke

1985
Maturation-related changes in dopamine-induced relaxation of isolated rabbit pulmonary artery.
    Pediatric research, 1988, Volume: 24, Issue:2

    Topics: Aging; Animals; Dopamine; Dose-Response Relationship, Drug; Female; Flupenthixol; Male; Metocloprami

1988
[Sonographic studies during drug treatment of diabetic gastroparesis].
    Deutsche medizinische Wochenschrift (1946), 1988, Jun-16, Volume: 113, Issue:24

    Topics: Adult; Cisapride; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; Gastric Emptying; Gastro

1988
Involvement of enteric neurones in the response of guinea-pig ileum preparations to metoclopramide.
    British journal of pharmacology, 1986, Volume: 88, Issue:1

    Topics: Acetylcholine; Animals; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Guinea Pigs; Ileum;

1986
Swallow-evoked peristalsis in opossum esophagus: role of cholinergic mechanisms.
    The American journal of physiology, 1986, Volume: 251, Issue:6 Pt 1

    Topics: Animals; Atropine; Deglutition; Esophagus; Evoked Potentials; Female; Gastrointestinal Motility; Mal

1986
Motor-stimulating properties of cisapride on isolated gastrointestinal preparations of the guinea pig.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Cisapride; Dose-Response Relationship, Drug; Electric Stimulation;

1985
Differential effects of metoclopramide and zetidoline on gastrointestinal motility.
    European journal of pharmacology, 1985, Jan-22, Volume: 108, Issue:2

    Topics: Animals; Cholinesterase Inhibitors; Gastric Emptying; Gastrointestinal Motility; Guinea Pigs; Ileum;

1985
A comparison of the stimulatory effects of metoclopramide and cinitapride in the guinea-pig isolated ileum.
    Journal of autonomic pharmacology, 1985, Volume: 5, Issue:1

    Topics: Acetylcholine; Animals; Benzamides; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Guinea

1985
Contractions of the stomach and duodenum induced by trimebutine in conscious fasted dogs.
    Nihon Heikatsukin Gakkai zasshi, 1985, Volume: 21, Issue:1

    Topics: Action Potentials; Animals; Benzoates; Dogs; Duodenum; Gastrointestinal Motility; Male; Metocloprami

1985
A comparative study on the effects of domperidone, metoclopramide, clebopride and trimebutine on the gastro-duodenal preparation of the guinea pig.
    Japanese journal of pharmacology, 1985, Volume: 39, Issue:2

    Topics: Animals; Benzamides; Benzoates; Domperidone; Drug Antagonism; Duodenum; Female; Gastrointestinal Mot

1985
The effect of metoclopramide (Primperan) during gastroscopic observation of the antrum and the pylorus.
    Gastrointestinal endoscopy, 1974, Volume: 21, Issue:2

    Topics: Duodenum; Gastroscopy; Humans; Male; Metoclopramide; Middle Aged; Muscle Contraction; Pyloric Antrum

1974
The effects of metoclopramide on some isolated intestinal preparations.
    Postgraduate medical journal, 1973, Volume: 49 Suppl 4

    Topics: 5-Hydroxytryptophan; Acetylcholine; Anesthesia, Local; Animals; Dose-Response Relationship, Drug; Fe

1973
[Effects of metoclopramide and procaine on isolated rat stomach strip].
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 204, Issue:1

    Topics: Acetylcholine; Animals; Calcium; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techn

1973
Pharmacological analysis of the effects of metoclopramide on the guinea-pig ileum in vitro.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 204, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pig

1973
Gastroduodenal motility and synchronization.
    Postgraduate medical journal, 1973, Volume: 49 Suppl 4

    Topics: Animals; Dogs; Duodenum; Gastrointestinal Motility; Humans; Metoclopramide; Muscle Contraction; Musc

1973