Page last updated: 2024-10-31

metoclopramide and Migraine without Aura

metoclopramide has been researched along with Migraine without Aura in 3 studies

Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.

Migraine without Aura: Recurrent unilateral pulsatile headaches, not preceded or accompanied by an aura, in attacks lasting 4-72 hours. It is characterized by PAIN of moderate to severe intensity; aggravated by physical activity; and associated with NAUSEA and / or PHOTOPHOBIA and PHONOPHOBIA. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"Patients presenting with moderate to severe intensity migraine without aura were randomized to receive either 400 mg of iVPA or 10 mg intramuscular metoclopramide + 6 mg SQ sumatriptan (30 patients in each study arm)."5.17A randomized open-label study of sodium valproate vs sumatriptan and metoclopramide for prolonged migraine headache. ( Bakhshayesh, B; Hatamian, H; Hossieninezhad, M; Rezania, K; Seyed Saadat, SM, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balbin, JE1
Nerenberg, R1
Baratloo, A1
Friedman, BW2
Mulvey, L1
Esses, D1
Solorzano, C1
Paternoster, J1
Lipton, RB1
Gallagher, EJ1
Bakhshayesh, B1
Seyed Saadat, SM1
Rezania, K1
Hatamian, H1
Hossieninezhad, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Intravenous Fluids in Benign Headaches Trail: A Randomized Single Blind Clinical Trial[NCT03185130]Phase 458 participants (Actual)Interventional2017-05-16Completed
Oral v. Parenteral Medications for the Emergency Management of Acute Migraine: a Pilot Randomized Control Trial[NCT05983354]55 participants (Anticipated)Interventional2024-01-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for metoclopramide and Migraine without Aura

ArticleYear
Intravenous fluids for migraine: a post hoc analysis of clinical trial data.
    The American journal of emergency medicine, 2016, Volume: 34, Issue:4

    Topics: Adult; Dopamine D2 Receptor Antagonists; Emergency Service, Hospital; Female; Fluid Therapy; Humans;

2016
Metoclopramide for acute migraine: a dose-finding randomized clinical trial.
    Annals of emergency medicine, 2011, Volume: 57, Issue:5

    Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Analgesics; Dose-Response Relationship, Drug; Double-

2011
A randomized open-label study of sodium valproate vs sumatriptan and metoclopramide for prolonged migraine headache.
    The American journal of emergency medicine, 2013, Volume: 31, Issue:3

    Topics: Acute Disease; Adult; Analgesics; Dopamine Antagonists; Drug Therapy, Combination; Female; GABA Agen

2013