metoclopramide has been researched along with Migraine without Aura in 3 studies
Metoclopramide: A dopamine D2 antagonist that is used as an antiemetic.
metoclopramide : A member of the class of benzamides resulting from the formal condensation of 4-amino-5-chloro-2-methoxybenzoic acid with the primary amino group of N,N-diethylethane-1,2-diamine.
Migraine without Aura: Recurrent unilateral pulsatile headaches, not preceded or accompanied by an aura, in attacks lasting 4-72 hours. It is characterized by PAIN of moderate to severe intensity; aggravated by physical activity; and associated with NAUSEA and / or PHOTOPHOBIA and PHONOPHOBIA. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients presenting with moderate to severe intensity migraine without aura were randomized to receive either 400 mg of iVPA or 10 mg intramuscular metoclopramide + 6 mg SQ sumatriptan (30 patients in each study arm)." | 5.17 | A randomized open-label study of sodium valproate vs sumatriptan and metoclopramide for prolonged migraine headache. ( Bakhshayesh, B; Hatamian, H; Hossieninezhad, M; Rezania, K; Seyed Saadat, SM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balbin, JE | 1 |
| Nerenberg, R | 1 |
| Baratloo, A | 1 |
| Friedman, BW | 2 |
| Mulvey, L | 1 |
| Esses, D | 1 |
| Solorzano, C | 1 |
| Paternoster, J | 1 |
| Lipton, RB | 1 |
| Gallagher, EJ | 1 |
| Bakhshayesh, B | 1 |
| Seyed Saadat, SM | 1 |
| Rezania, K | 1 |
| Hatamian, H | 1 |
| Hossieninezhad, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intravenous Fluids in Benign Headaches Trail: A Randomized Single Blind Clinical Trial[NCT03185130] | Phase 4 | 58 participants (Actual) | Interventional | 2017-05-16 | Completed | ||
| Oral v. Parenteral Medications for the Emergency Management of Acute Migraine: a Pilot Randomized Control Trial[NCT05983354] | 55 participants (Anticipated) | Interventional | 2024-01-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for metoclopramide and Migraine without Aura
| Article | Year |
|---|---|
Intravenous fluids for migraine: a post hoc analysis of clinical trial data.
Topics: Adult; Dopamine D2 Receptor Antagonists; Emergency Service, Hospital; Female; Fluid Therapy; Humans; | 2016 |
Metoclopramide for acute migraine: a dose-finding randomized clinical trial.
Topics: Acute Disease; Adult; Akathisia, Drug-Induced; Analgesics; Dose-Response Relationship, Drug; Double- | 2011 |
A randomized open-label study of sodium valproate vs sumatriptan and metoclopramide for prolonged migraine headache.
Topics: Acute Disease; Adult; Analgesics; Dopamine Antagonists; Drug Therapy, Combination; Female; GABA Agen | 2013 |